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Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation. Commun Biol. 2021 Jun 03; 4(1):685.
Mohammadi MR, Rodriguez SM, Luong JC, Li S, Cao R, Alshetaiwi H, Lau H, Davtyan H, Jones MB, Jafari M, Kessenbrock K, Villalta SA, de Vos P, Zhao W, Lakey JRT. PMID: 34083739.
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Let-7f miRNA regulates SDF-1a- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release. Cell Death Dis. 2021 May 20; 12(6):516.
Egea V, Kessenbrock K, Lawson D, Bartelt A, Weber C, Ries C. PMID: 34016957.
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PubMed Mentions: Fields:
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Microfluidic platform accelerates tissue processing into single cells for molecular analysis and primary culture models. Nat Commun. 2021 05 17; 12(1):2858.
Lombardo JA, Aliaghaei M, Nguyen QH, Kessenbrock K, Haun JB. PMID: 34001902.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy. Lab Chip. 2021 04 07; 21(7):1333-1351.
Hachey SJ, Movsesyan S, Nguyen QH, Burton-Sojo G, Tankazyan A, Wu J, Hoang T, Zhao D, Wang S, Hatch MM, Celaya E, Gomez S, Chen GT, Davis RT, Nee K, Pervolarakis N, Lawson DA, Kessenbrock K, Lee AP, Lowengrub J, Waterman ML, Hughes CCW. PMID: 33605955.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Single-Cell Transcriptome Analysis Workflow for Splenic Myeloid-Derived Suppressor Cells from Murine Breast Cancer Models. Methods Mol Biol. 2021; 2236:177-187.
Alshetaiwi H, Pervolarakis N, Nguyen QH, Kessenbrock K. PMID: 33237548.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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OVOL1 Regulates Psoriasis-Like Skin Inflammation and Epidermal Hyperplasia. J Invest Dermatol. 2021 Jun; 141(6):1542-1552.
Sun P, Vu R, Dragan M, Haensel D, Gutierrez G, Nguyen Q, Greenberg E, Chen Z, Wu J, Atwood S, Pearlman E, Shi Y, Han W, Kessenbrock K, Dai X. PMID: 33333123.
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Integrated Single-Cell Transcriptomics and Chromatin Accessibility Analysis Reveals Regulators of Mammary Epithelial Cell Identity. Cell Rep. 2020 10 20; 33(3):108273.
Pervolarakis N, Nguyen QH, Williams J, Gong Y, Gutierrez G, Sun P, Jhutty D, Zheng GXY, Nemec CM, Dai X, Watanabe K, Kessenbrock K. PMID: 33086071.
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PubMed Mentions:
6 Fields:
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Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics. Cell Rep. 2020 03 17; 30(11):3932-3947.e6.
Haensel D, Jin S, Sun P, Cinco R, Dragan M, Nguyen Q, Cang Z, Gong Y, Vu R, MacLean AL, Kessenbrock K, Gratton E, Nie Q, Dai X. PMID: 32187560.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics. Sci Immunol. 2020 02 21; 5(44).
Alshetaiwi H, Pervolarakis N, McIntyre LL, Ma D, Nguyen Q, Rath JA, Nee K, Hernandez G, Evans K, Torosian L, Silva A, Walsh C, Kessenbrock K. PMID: 32086381.
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PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
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Unraveling Heterogeneity in Epithelial Cell Fates of the Mammary Gland and Breast Cancer. Cancers (Basel). 2019 Sep 24; 11(10).
Samocha A, Doh H, Kessenbrock K, Roose JP. PMID: 31554261.
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Single-cell landscape in mammary epithelium reveals bipotent-like cells associated with breast cancer risk and outcome. Commun Biol. 2019; 2:306.
Chen W, Morabito SJ, Kessenbrock K, Enver T, Meyer KB, Teschendorff AE. PMID: 31428694.
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Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds. Nat Commun. 2019 02 08; 10(1):650.
Guerrero-Juarez CF, Dedhia PH, Jin S, Ruiz-Vega R, Ma D, Liu Y, Yamaga K, Shestova O, Gay DL, Yang Z, Kessenbrock K, Nie Q, Pear WS, Cotsarelis G, Plikus MV. PMID: 30737373.
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PubMed Mentions:
62 Fields:
Translation:
AnimalsCells
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Tumour heterogeneity and metastasis at single-cell resolution. Nat Cell Biol. 2018 12; 20(12):1349-1360.
Lawson DA, Kessenbrock K, Davis RT, Pervolarakis N, Werb Z. PMID: 30482943.
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PubMed Mentions:
82 Fields:
Translation:
HumansCells
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Microfluidic filter device with nylon mesh membranes efficiently dissociates cell aggregates and digested tissue into single cells. Lab Chip. 2018 09 11; 18(18):2776-2786.
Qiu X, Lombardo JA, Westerhof TM, Pennell M, Ng A, Alshetaiwi H, Luna BM, Nelson EL, Kessenbrock K, Hui EE, Haun JB. PMID: 30090895.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Experimental Considerations for Single-Cell RNA Sequencing Approaches. Front Cell Dev Biol. 2018; 6:108.
Nguyen QH, Pervolarakis N, Nee K, Kessenbrock K. PMID: 30234113.
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PubMed Mentions:
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Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity. Nat Commun. 2018 05 23; 9(1):2028.
Nguyen QH, Pervolarakis N, Blake K, Ma D, Davis RT, James N, Phung AT, Willey E, Kumar R, Jabart E, Driver I, Rock J, Goga A, Khan SA, Lawson DA, Werb Z, Kessenbrock K. PMID: 29795293.
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PubMed Mentions:
66 Fields:
Translation:
HumansCells
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Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers. Genes Dev. 2018 02 01; 32(3-4):244-257.
Takai K, Drain AP, Lawson DA, Littlepage LE, Karpuj M, Kessenbrock K, Le A, Inoue K, Weaver VM, Werb Z. PMID: 29483153.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Diverse regulation of mammary epithelial growth and branching morphogenesis through noncanonical Wnt signaling. Proc Natl Acad Sci U S A. 2017 03 21; 114(12):3121-3126.
Kessenbrock K, Smith P, Steenbeek SC, Pervolarakis N, Kumar R, Minami Y, Goga A, Hinck L, Werb Z. PMID: 28270600.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression. Nat Med. 2016 11; 22(11):1321-1329.
Horiuchi D, Camarda R, Zhou AY, Yau C, Momcilovic O, Balakrishnan S, Corella AN, Eyob H, Kessenbrock K, Lawson DA, Marsh LA, Anderton BN, Rohrberg J, Kunder R, Bazarov AV, Yaswen P, McManus MT, Rugo HS, Werb Z, Goga A. PMID: 27775705.
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PubMed Mentions:
63 Fields:
Translation:
HumansAnimalsCells
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Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps. Sci Transl Med. 2016 10 19; 8(361):361ra138.
Park J, Wysocki RW, Amoozgar Z, Maiorino L, Fein MR, Jorns J, Schott AF, Kinugasa-Katayama Y, Lee Y, Won NH, Nakasone ES, Hearn SA, Küttner V, Qiu J, Almeida AS, Perurena N, Kessenbrock K, Goldberg MS, Egeblad M. PMID: 27798263.
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PubMed Mentions:
172 Fields:
Translation:
HumansAnimalsCells
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Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells. Nature. 2015 Oct 01; 526(7571):131-5.
Lawson DA, Bhakta NR, Kessenbrock K, Prummel KD, Yu Y, Takai K, Zhou A, Eyob H, Balakrishnan S, Wang CY, Yaswen P, Goga A, Werb Z. PMID: 26416748.
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PubMed Mentions:
283 Fields:
Translation:
HumansAnimalsCells
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Matrix metalloproteinases in stem cell regulation and cancer. Matrix Biol. 2015 May-Jul; 44-46:184-90.
Kessenbrock K, Wang CY, Werb Z. PMID: 25661772.
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PubMed Mentions:
61 Fields:
Translation:
HumansCells
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A role for matrix metalloproteinases in regulating mammary stem cell function via the Wnt signaling pathway. Cell Stem Cell. 2013 Sep 05; 13(3):300-13.
Kessenbrock K, Dijkgraaf GJ, Lawson DA, Littlepage LE, Shahi P, Pieper U, Werb Z. PMID: 23871604.
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PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury. J Clin Invest. 2012 Jul; 122(7):2661-71.
Caudrillier A, Kessenbrock K, Gilliss BM, Nguyen JX, Marques MB, Monestier M, Toy P, Werb Z, Looney MR. PMID: 22684106.
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PubMed Mentions:
325 Fields:
Translation:
HumansAnimalsCells
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Measuring matrix metalloproteinase activity in macrophages and polymorphonuclear leukocytes. Curr Protoc Immunol. 2011 Apr; Chapter 14:Unit14.24.
Kessenbrock K, Brown M, Werb Z. PMID: 21462166.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Tailor-made inflammation: how neutrophil serine proteases modulate the inflammatory response. J Mol Med (Berl). 2011 Jan; 89(1):23-8.
Kessenbrock K, Dau T, Jenne DE. PMID: 20809089.
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PubMed Mentions:
31 Fields:
Translation:
Cells
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Matrix metalloproteinases: regulators of the tumor microenvironment. Cell. 2010 Apr 02; 141(1):52-67.
Kessenbrock K, Plaks V, Werb Z. PMID: 20371345.
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PubMed Mentions:
1503 Fields:
Translation:
HumansAnimals
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Netting neutrophils in autoimmune small-vessel vasculitis. Nat Med. 2009 Jun; 15(6):623-5.
Kessenbrock K, Krumbholz M, Schönermarck U, Back W, Gross WL, Werb Z, Gröne HJ, Brinkmann V, Jenne DE. PMID: 19448636.
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PubMed Mentions:
514 Fields:
Translation:
Cells
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Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin. J Clin Invest. 2008 Jul; 118(7):2438-47.
Kessenbrock K, Fröhlich L, Sixt M, Lämmermann T, Pfister H, Bateman A, Belaaouaj A, Ring J, Ollert M, Fässler R, Jenne DE. PMID: 18568075.
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PubMed Mentions:
158 Fields:
Translation:
AnimalsCells
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Lifeact: a versatile marker to visualize F-actin. Nat Methods. 2008 Jul; 5(7):605-7.
Riedl J, Crevenna AH, Kessenbrock K, Yu JH, Neukirchen D, Bista M, Bradke F, Jenne D, Holak TA, Werb Z, Sixt M, Wedlich-Soldner R. PMID: 18536722.
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PubMed Mentions:
899 Fields:
Translation:
HumansAnimalsCells
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Synthetic peptides: the future of patient management in systemic rheumatic diseases? Curr Med Chem. 2007; 14(26):2831-8.
Kessenbrock K, Raijmakers R, Fritzler MJ, Mahler M. PMID: 18045129.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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International multicenter evaluation of autoantibodies to ribosomal P proteins. Clin Vaccine Immunol. 2006 Jan; 13(1):77-83.
Mahler M, Kessenbrock K, Szmyrka M, Takasaki Y, Garcia-De La Torre I, Shoenfeld Y, Hiepe F, Shun-le C, von Mühlen CA, Locht H, Höpfl P, Wiik A, Reeves W, Fritzler MJ. PMID: 16426003.
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PubMed Mentions:
20 Fields:
Translation:
Humans