Jered Haun

Title(s)	Assistant Professor, Biomedical Engineering
School	Samueli School of Engineering
Address	3107 Natural Sciences II Zot 2715 Irvine CA 92697
Phone	(949) 824-1243
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Research

research activities and funding

Microfluidic tumor tissue processing platform for single cell diagnostics
NIH R33CA251006May 1, 2021 - Apr 30, 2024
Role: Principal Investigator

Harnessing the biophysics of multivalent nanoparticle adhesion to control cell targeting and internalization
NIH R21EB027883Jul 1, 2020 - Jun 30, 2021
Role: Principal Investigator

Transforming fluorescence lifetime imaging microscopy into a fast and simple platform for high-content molecular analysis
NIH R21CA206953Aug 1, 2016 - Jul 31, 2020
Role: Principal Investigator

Molecular Detection and Profiling of Circulating Tumor Cells
NIH F32CA144139Jul 1, 2010 - May 7, 2011
Role: Principal Investigator

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Mechanical Processing of Lipoaspirate With a Fluidic Device Platform Promotes Wound Healing Transcriptional Programs and Angiogenesis In Vitro. Aesthet Surg J. 2025 Apr 10. Lombardo JA, Banyard DA, Zalazar D, Ziegler M, Sorensen AM, Phummirat P, Widgerow AD, Haun JB. PMID: 40205801.

View in: PubMed Mentions: Fields:
Gen General Surgery
Multiplexed Immunoassay Using Quantum Dots to Monitor Proteins Secreted from Single Cells at Near-Single Molecule Resolution. Methods Mol Biol. 2023; 2660:187-206. Naveen VY, Deng T, Herrera V, Haun JB. PMID: 37191798.

View in: PubMed Mentions: Fields:
Mol Molecular Biology
Fluidic Device System for Mechanical Processing and Filtering of Human Lipoaspirate Enhances Recovery of Mesenchymal Stem Cells. Plast Reconstr Surg. 2023 01 01; 151(1):72e-84e. Lombardo JA, Banyard DA, Widgerow AD, Haun JB. PMID: 36205654; PMCID: PMC10156086.

View in: PubMed Mentions: 2 Fields:
Gen General Surgery
Translation:Humans Cells
Phasor Analysis of Fluorescence Lifetime Enables Quantitative Multiplexed Molecular Imaging of Three Probes. Anal Chem. 2022 10 18; 94(41):14185-14194. Rahim MK, Zhao J, Patel HV, Lagouros HA, Kota R, Fernandez I, Gratton E, Haun JB. PMID: 36190014; PMCID: PMC10681155.

View in: PubMed Mentions: 9 Fields:
Che Chemistry Techniques
Optimization of Mechanical Tissue Dissociation Using an Integrated Microfluidic Device for Improved Generation of Single Cells Following Digestion. Front Bioeng Biotechnol. 2022; 10:841046. Aliaghaei M, Haun JB. PMID: 35211466; PMCID: PMC8861371.

View in: PubMed Mentions: 4
Microfluidic Device Technologies for Digestion, Disaggregation, and Filtration of Tissue Samples for Single Cell Applications. Methods Mol Biol. 2022; 2394:81-92. Lombardo JA, Haun JB. PMID: 35094323.

View in: PubMed Mentions: Fields:
Mol Molecular Biology
Translation:Cells
Multiplexed Detection of Secreted Cytokines at near-Molecular Resolution Elucidates Macrophage Polarization Heterogeneity. Anal Chem. 2022 01 18; 94(2):658-668. Herrera V, Hsu SJ, Naveen VY, Liu WF, Haun JB. PMID: 34936345.

View in: PubMed Mentions: 1 Fields:
Che Chemistry Techniques
Translation:Cells
Quantifying and controlling bond multivalency for advanced nanoparticle targeting to cells. Nano Converg. 2021 Nov 30; 8(1):38. Makhani EY, Zhang A, Haun JB. PMID: 34846580; PMCID: PMC8633263.

View in: PubMed Mentions: 10
Microfluidic platform accelerates tissue processing into single cells for molecular analysis and primary culture models. Nat Commun. 2021 05 17; 12(1):2858. Lombardo JA, Aliaghaei M, Nguyen QH, Kessenbrock K, Haun JB. PMID: 34001902; PMCID: PMC8128882.

View in: PubMed Mentions: 13 Fields:
Bio Biology Sci Science
Translation:Humans Animals Cells
Pushing the limits of detection for proteins secreted from single cells using quantum dots. Analyst. 2019 Jan 28; 144(3):980-989. Herrera V, Hsu SJ, Rahim MK, Chen C, Nguyen L, Liu WF, Haun JB. PMID: 30270391; PMCID: PMC6349524.

View in: PubMed Mentions: 10 Fields:
Che Chemistry Techniques
Translation:Humans Cells
Microfluidic filter device with nylon mesh membranes efficiently dissociates cell aggregates and digested tissue into single cells. Lab Chip. 2018 09 11; 18(18):2776-2786. Qiu X, Lombardo JA, Westerhof TM, Pennell M, Ng A, Alshetaiwi H, Luna BM, Nelson EL, Kessenbrock K, Hui EE, Haun JB. PMID: 30090895; PMCID: PMC6171522.

View in: PubMed Mentions: 9 Fields:
Bio Biotechnology Che Chemistry
Translation:Humans Animals Cells
Extracting multivalent detachment rates from heterogeneous nanoparticle populations. Phys Chem Chem Phys. 2018 Aug 22; 20(33):21430-21440. Wang M, Allard J, Haun JB. PMID: 30087954.

View in: PubMed Mentions: 1 Fields:
Bio Biophysics Che Chemistry Phy Physics
Microfluidic channel optimization to improve hydrodynamic dissociation of cell aggregates and tissue. Sci Rep. 2018 02 09; 8(1):2774. Qiu X, Huang JH, Westerhof TM, Lombardo JA, Henrikson KM, Pennell M, Pourfard PP, Nelson EL, Nath P, Haun JB. PMID: 29426941; PMCID: PMC5807353.

View in: PubMed Mentions: 11 Fields:
Sci Science
Translation:Humans Animals Cells
Microfluidic device for rapid digestion of tissues into cellular suspensions. Lab Chip. 2017 09 26; 17(19):3300-3309. Qiu X, Westerhof TM, Karunaratne AA, Werner EM, Pourfard PP, Nelson EL, Hui EE, Haun JB. PMID: 28850139; PMCID: PMC5614870.

View in: PubMed Mentions: 5 Fields:
Bio Biotechnology Che Chemistry
Translation:Animals Cells
Fluctuation Spectroscopy Analysis of Glucose Capped Gold Nanoparticles. Langmuir. 2016 12 20; 32(50):13409-13417. Porcaro F, Miao Y, Kota R, Haun JB, Polzonetti G, Battocchio C, Gratton E. PMID: 27935716; PMCID: PMC5470844.

View in: PubMed Mentions: 1 Fields:
Che Chemistry
Translation:Humans Cells
Evolution of Multivalent Nanoparticle Adhesion via Specific Molecular Interactions. Langmuir. 2016 12 13; 32(49):13124-13136. Wang M, Ravindranath SR, Rahim MK, Botvinick EL, Haun JB. PMID: 27797529; PMCID: PMC5321555.

View in: PubMed Mentions: 2 Fields:
Che Chemistry
Phenotypic Analysis of Stromal Vascular Fraction after Mechanical Shear Reveals Stress-Induced Progenitor Populations. Plast Reconstr Surg. 2016 Aug; 138(2):237e-247e. Banyard DA, Sarantopoulos CN, Borovikova AA, Qiu X, Wirth GA, Paydar KZ, Haun JB, Evans GRD, Widgerow AD. PMID: 27465185; PMCID: PMC5845841.

View in: PubMed Mentions: 27 Fields:
Gen General Surgery
Translation:Humans Cells
Macrophage secretion heterogeneity in engineered microenvironments revealed using a microwell platform. Integr Biol (Camb). 2016 07 11; 8(7):751-60. McWhorter FY, Smith TD, Luu TU, Rahim MK, Haun JB, Liu WF. PMID: 27291691.

View in: PubMed Mentions: 10 Fields:
Bio Biology
Translation:Animals Cells
Enhancing reactivity for bioorthogonal pretargeting by unmasking antibody-conjugated trans-cyclooctenes. Bioconjug Chem. 2015 Feb 18; 26(2):352-60. Rahim MK, Kota R, Haun JB. PMID: 25584926; PMCID: PMC5022565.

View in: PubMed Mentions: 24 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Microfluidic device for mechanical dissociation of cancer cell aggregates into single cells. Lab Chip. 2015 Jan 07; 15(1):339-350. Qiu X, De Jesus J, Pennell M, Troiani M, Haun JB. PMID: 25377468; PMCID: PMC4301619.

View in: PubMed Mentions: 16 Fields:
Bio Biotechnology Che Chemistry
Translation:Humans Cells
Using engineered single-chain antibodies to correlate molecular binding properties and nanoparticle adhesion dynamics. Langmuir. 2011 Nov 15; 27(22):13701-12. Haun JB, Pepper LR, Boder ET, Hammer DA. PMID: 21942413; PMCID: PMC3257898.

View in: PubMed Mentions: 4 Fields:
Che Chemistry
Translation:Cells
Probing intracellular biomarkers and mediators of cell activation using nanosensors and bioorthogonal chemistry. ACS Nano. 2011 Apr 26; 5(4):3204-13. Haun JB, Devaraj NK, Marinelli BS, Lee H, Weissleder R. PMID: 21351804; PMCID: PMC3088084.

View in: PubMed Mentions: 27 Fields:
Nan Nanotechnology
Translation:Humans Cells
Micro-NMR for rapid molecular analysis of human tumor samples. Sci Transl Med. 2011 Feb 23; 3(71):71ra16. Haun JB, Castro CM, Wang R, Peterson VM, Marinelli BS, Lee H, Weissleder R. PMID: 21346169; PMCID: PMC3086073.

View in: PubMed Mentions: 98 Fields:
Med Medicine (General)Sci Science
Translation:Humans
Molecular detection of biomarkers and cells using magnetic nanoparticles and diagnostic magnetic resonance. Methods Mol Biol. 2011; 726:33-49. Haun JB, Yoon TJ, Lee H, Weissleder R. PMID: 21424441.

View in: PubMed Mentions: 12 Fields:
Mol Molecular Biology
Translation:Cells
Carboxymethylated polyvinyl alcohol stabilizes doped ferrofluids for biological applications. Adv Mater. 2010 Dec 01; 22(45):5168-72. Liong M, Shao H, Haun JB, Lee H, Weissleder R. PMID: 20859943; PMCID: PMC2993874.

View in: PubMed Mentions: 16 Fields:
Bio Biophysics Che Chemistry
Tunable leuko-polymersomes that adhere specifically to inflammatory markers. Langmuir. 2010 Sep 07; 26(17):14089-96. Robbins GP, Saunders RL, Haun JB, Rawson J, Therien MJ, Hammer DA. PMID: 20704280; PMCID: PMC3413312.

View in: PubMed Mentions: 26 Fields:
Che Chemistry
Translation:Humans Cells
Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection. Nat Nanotechnol. 2010 Sep; 5(9):660-5. Haun JB, Devaraj NK, Hilderbrand SA, Lee H, Weissleder R. PMID: 20676091; PMCID: PMC2934903.

View in: PubMed Mentions: 119 Fields:
Nan Nanotechnology
Magnetic nanoparticle biosensors. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010 May-Jun; 2(3):291-304. Haun JB, Yoon TJ, Lee H, Weissleder R. PMID: 20336708.

View in: PubMed Mentions: 101 Fields:
Bio Biotechnology Nan Nanotechnology
Translation:Humans Animals Cells
Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition. Angew Chem Int Ed Engl. 2009; 48(38):7013-6. Devaraj NK, Upadhyay R, Haun JB, Hilderbrand SA, Weissleder R. PMID: 19697389; PMCID: PMC2790075.

View in: PubMed Mentions: 135 Fields:
Che Chemistry
Quantifying nanoparticle adhesion mediated by specific molecular interactions. Langmuir. 2008 Aug 19; 24(16):8821-32. Haun JB, Hammer DA. PMID: 18630976.

View in: PubMed Mentions: 41 Fields:
Che Chemistry
Translation:Humans
Leuko-polymersomes. Faraday Discuss. 2008; 139:129-41; discussion 213-28, 419-20. Hammer DA, Robbins GP, Haun JB, Lin JJ, Qi W, Smith LA, Ghoroghchian PP, Therien MJ, Bates FS. PMID: 19048993; PMCID: PMC2714229.

View in: PubMed Mentions: 19 Fields:
Che Chemistry
Neutrophil traction stresses are concentrated in the uropod during migration. Biophys J. 2007 Apr 01; 92(7):L58-60. Smith LA, Aranda-Espinoza H, Haun JB, Dembo M, Hammer DA. PMID: 17218464; PMCID: PMC1864841.

View in: PubMed Mentions: 55 Fields:
Bio Biophysics
Translation:Humans Cells
Interplay between shear stress and adhesion on neutrophil locomotion. Biophys J. 2007 Jan 15; 92(2):632-40. Smith LA, Aranda-Espinoza H, Haun JB, Hammer DA. PMID: 17071667; PMCID: PMC1751380.

View in: PubMed Mentions: 13 Fields:
Bio Biophysics
Translation:Humans Cells
Clearance of complement by human vascular endothelial cells: effects of hypoxia/reoxygenation and IL-1beta activation. Transpl Int. 2005 Apr; 18(4):475-82. Haun JB, Baldwin WM, Alevriadou BR. PMID: 15773971.

View in: PubMed Mentions: 1 Fields:
Tra Transplantation
Translation:Humans Cells