Jered Haun

Title(s)	Assistant Professor, Biomedical Engineering
Address	3107 Natural Sciences II Zot 2715 Irvine CA 92697
Phone	(949) 824-1243
vCard	Download vCard

Research

Research Activities and Funding

Microfluidic tumor tissue processing platform for single cell diagnostics
NIH R33CA251006May 1, 2021 - Apr 30, 2024
Role: Principal Investigator

Harnessing the biophysics of multivalent nanoparticle adhesion to control cell targeting and internalization
NIH R21EB027883Jul 1, 2020 - Jun 30, 2021
Role: Principal Investigator

Transforming fluorescence lifetime imaging microscopy into a fast and simple platform for high-content molecular analysis
NIH R21CA206953Aug 1, 2016 - Jul 31, 2020
Role: Principal Investigator

Molecular Detection and Profiling of Circulating Tumor Cells
NIH F32CA144139Jul 1, 2010 - May 7, 2011
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Microfluidic platform accelerates tissue processing into single cells for molecular analysis and primary culture models. Nat Commun. 2021 05 17; 12(1):2858. Lombardo JA, Aliaghaei M, Nguyen QH, Kessenbrock K, Haun JB. PMID: 34001902.

View in: PubMed Mentions: 1 Fields:
Bio Biology Sci Science
Translation:Humans Animals Cells
Pushing the limits of detection for proteins secreted from single cells using quantum dots. Analyst. 2019 Jan 28; 144(3):980-989. Herrera V, Hsu SJ, Rahim MK, Chen C, Nguyen L, Liu WF, Haun JB. PMID: 30270391.

View in: PubMed Mentions: 8 Fields:
Che Chemistry Techniques
Translation:Humans Cells
Microfluidic filter device with nylon mesh membranes efficiently dissociates cell aggregates and digested tissue into single cells. Lab Chip. 2018 09 11; 18(18):2776-2786. Qiu X, Lombardo JA, Westerhof TM, Pennell M, Ng A, Alshetaiwi H, Luna BM, Nelson EL, Kessenbrock K, Hui EE, Haun JB. PMID: 30090895.

View in: PubMed Mentions: 5 Fields:
Bio Biotechnology Che Chemistry
Translation:Humans Animals Cells
Extracting multivalent detachment rates from heterogeneous nanoparticle populations. Phys Chem Chem Phys. 2018 Aug 22; 20(33):21430-21440. Wang M, Allard J, Haun JB. PMID: 30087954.

View in: PubMed Mentions: Fields:
Bio Biophysics Che Chemistry Phy Physics
Microfluidic channel optimization to improve hydrodynamic dissociation of cell aggregates and tissue. Sci Rep. 2018 02 09; 8(1):2774. Qiu X, Huang JH, Westerhof TM, Lombardo JA, Henrikson KM, Pennell M, Pourfard PP, Nelson EL, Nath P, Haun JB. PMID: 29426941.

View in: PubMed Mentions: 8 Fields:
Sci Science
Translation:Humans Animals Cells
Microfluidic device for rapid digestion of tissues into cellular suspensions. Lab Chip. 2017 09 26; 17(19):3300-3309. Qiu X, Westerhof TM, Karunaratne AA, Werner EM, Pourfard PP, Nelson EL, Hui EE, Haun JB. PMID: 28850139.

View in: PubMed Mentions: 4 Fields:
Bio Biotechnology Che Chemistry
Translation:Animals Cells
Fluctuation Spectroscopy Analysis of Glucose Capped Gold Nanoparticles. Langmuir. 2016 12 20; 32(50):13409-13417. Porcaro F, Miao Y, Kota R, Haun JB, Polzonetti G, Battocchio C, Gratton E. PMID: 27935716.

View in: PubMed Mentions: 1 Fields:
Che Chemistry
Translation:Humans Cells
Evolution of Multivalent Nanoparticle Adhesion via Specific Molecular Interactions. Langmuir. 2016 12 13; 32(49):13124-13136. Wang M, Ravindranath SR, Rahim MK, Botvinick EL, Haun JB. PMID: 27797529.

View in: PubMed Mentions: Fields:
Che Chemistry
Phenotypic Analysis of Stromal Vascular Fraction after Mechanical Shear Reveals Stress-Induced Progenitor Populations. Plast Reconstr Surg. 2016 Aug; 138(2):237e-247e. Banyard DA, Sarantopoulos CN, Borovikova AA, Qiu X, Wirth GA, Paydar KZ, Haun JB, Evans GRD, Widgerow AD. PMID: 27465185.

View in: PubMed Mentions: 12 Fields:
Gen General Surgery
Translation:Humans Cells
Macrophage secretion heterogeneity in engineered microenvironments revealed using a microwell platform. Integr Biol (Camb). 2016 07 11; 8(7):751-60. McWhorter FY, Smith TD, Luu TU, Rahim MK, Haun JB, Liu WF. PMID: 27291691.

View in: PubMed Mentions: 3 Fields:
Bio Biology
Translation:Animals Cells
Enhancing reactivity for bioorthogonal pretargeting by unmasking antibody-conjugated trans-cyclooctenes. Bioconjug Chem. 2015 Feb 18; 26(2):352-60. Rahim MK, Kota R, Haun JB. PMID: 25584926.

View in: PubMed Mentions: 16 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Microfluidic device for mechanical dissociation of cancer cell aggregates into single cells. Lab Chip. 2015 Jan 07; 15(1):339-350. Qiu X, De Jesus J, Pennell M, Troiani M, Haun JB. PMID: 25377468.

View in: PubMed Mentions: 14 Fields:
Bio Biotechnology Che Chemistry
Translation:Humans Cells
Using engineered single-chain antibodies to correlate molecular binding properties and nanoparticle adhesion dynamics. Langmuir. 2011 Nov 15; 27(22):13701-12. Haun JB, Pepper LR, Boder ET, Hammer DA. PMID: 21942413.

View in: PubMed Mentions: 3 Fields:
Che Chemistry
Translation:Cells
Probing intracellular biomarkers and mediators of cell activation using nanosensors and bioorthogonal chemistry. ACS Nano. 2011 Apr 26; 5(4):3204-13. Haun JB, Devaraj NK, Marinelli BS, Lee H, Weissleder R. PMID: 21351804.

View in: PubMed Mentions: 22 Fields:
Nan Nanotechnology
Translation:Humans Cells
Micro-NMR for rapid molecular analysis of human tumor samples. Sci Transl Med. 2011 Feb 23; 3(71):71ra16. Haun JB, Castro CM, Wang R, Peterson VM, Marinelli BS, Lee H, Weissleder R. PMID: 21346169.

View in: PubMed Mentions: 78 Fields:
Med Medicine (General)Sci Science
Translation:Humans
Molecular detection of biomarkers and cells using magnetic nanoparticles and diagnostic magnetic resonance. Methods Mol Biol. 2011; 726:33-49. Haun JB, Yoon TJ, Lee H, Weissleder R. PMID: 21424441.

View in: PubMed Mentions: 10 Fields:
Mol Molecular Biology
Translation:Cells
Carboxymethylated polyvinyl alcohol stabilizes doped ferrofluids for biological applications. . 2010 Dec 01; 22(45):5168-72. Liong M, Shao H, Haun JB, Lee H, Weissleder R. PMID: 20859943.

View in: PubMed Mentions: 15 Fields:
Bio Biophysics Che Chemistry
Translation:Humans Cells
Tunable leuko-polymersomes that adhere specifically to inflammatory markers. Langmuir. 2010 Sep 07; 26(17):14089-96. Robbins GP, Saunders RL, Haun JB, Rawson J, Therien MJ, Hammer DA. PMID: 20704280.

View in: PubMed Mentions: 21 Fields:
Che Chemistry
Translation:Humans Cells
Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection. Nat Nanotechnol. 2010 Sep; 5(9):660-5. Haun JB, Devaraj NK, Hilderbrand SA, Lee H, Weissleder R. PMID: 20676091.

View in: PubMed Mentions: 101 Fields:
Nan Nanotechnology
Translation:Humans Animals Cells
Magnetic nanoparticle biosensors. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010 May-Jun; 2(3):291-304. Haun JB, Yoon TJ, Lee H, Weissleder R. PMID: 20336708.

View in: PubMed Mentions: 75 Fields:
Bio Biotechnology Nan Nanotechnology
Translation:Humans Animals Cells
Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition. Angew Chem Int Ed Engl. 2009; 48(38):7013-6. Devaraj NK, Upadhyay R, Haun JB, Hilderbrand SA, Weissleder R. PMID: 19697389.

View in: PubMed Mentions: 120 Fields:
Che Chemistry
Translation:Humans Cells
Quantifying nanoparticle adhesion mediated by specific molecular interactions. Langmuir. 2008 Aug 19; 24(16):8821-32. Haun JB, Hammer DA. PMID: 18630976.

View in: PubMed Mentions: 44 Fields:
Che Chemistry
Translation:Humans
Leuko-polymersomes. Faraday Discuss. 2008; 139:129-41; discussion 213-28, 419-20. Hammer DA, Robbins GP, Haun JB, Lin JJ, Qi W, Smith LA, Ghoroghchian PP, Therien MJ, Bates FS. PMID: 19048993.

View in: PubMed Mentions: 23 Fields:
Che Chemistry
Translation:Cells
Neutrophil traction stresses are concentrated in the uropod during migration. Biophys J. 2007 Apr 01; 92(7):L58-60. Smith LA, Aranda-Espinoza H, Haun JB, Dembo M, Hammer DA. PMID: 17218464.

View in: PubMed Mentions: 47 Fields:
Bio Biophysics
Translation:Humans Cells
Interplay between shear stress and adhesion on neutrophil locomotion. Biophys J. 2007 Jan 15; 92(2):632-40. Smith LA, Aranda-Espinoza H, Haun JB, Hammer DA. PMID: 17071667.

View in: PubMed Mentions: 19 Fields:
Bio Biophysics
Translation:Humans Cells
Clearance of complement by human vascular endothelial cells: effects of hypoxia/reoxygenation and IL-1beta activation. Transpl Int. 2005 Apr; 18(4):475-82. Haun JB, Baldwin WM, Alevriadou BR. PMID: 15773971.

View in: PubMed Mentions: 1 Fields:
Tra Transplantation
Translation:Humans Cells