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Interruption of the intratumor CD8+ T cell:Treg crosstalk improves the efficacy of PD-1 immunotherapy. Cancer Cell. 2024 Jun 10; 42(6):1051-1066.e7.
Geels SN, Moshensky A, Sousa RS, Murat C, Bustos MA, Walker BL, Singh R, Harbour SN, Gutierrez G, Hwang M, Mempel TR, Weaver CT, Nie Q, Hoon DSB, Ganesan AK, Othy S, Marangoni F. PMID: 38861924; PMCID: PMC11285091.
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HumansAnimalsCells
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Circadian control of tumor immunosuppression affects efficacy of immune checkpoint blockade. Nat Immunol. 2024 Jul; 25(7):1257-1269.
Fortin BM, Pfeiffer SM, Insua-Rodríguez J, Alshetaiwi H, Moshensky A, Song WA, Mahieu AL, Chun SK, Lewis AN, Hsu A, Adam I, Eng OS, Pannunzio NR, Seldin MM, Marazzi I, Marangoni F, Lawson DA, Kessenbrock K, Masri S. PMID: 38806707.
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1 Fields:
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HumansAnimalsCells
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Interruption of the Intratumor CD8:Treg Crosstalk Improves the Efficacy of PD-1 Immunotherapy. bioRxiv. 2023 May 18.
Geels SN, Moshensky A, Sousa RS, Walker BL, Singh R, Gutierrez G, Hwang M, Mempel TR, Nie Q, Othy S, Marangoni F. PMID: 37292782; PMCID: PMC10245792.
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Cyclodextrin metal-organic framework-based protein biocomposites. Biomater Sci. 2022 Nov 22; 10(23):6749-6754.
Di Palma G, Geels S, Carpenter BP, Talosig RA, Chen C, Marangoni F, Patterson JP. PMID: 36286095; PMCID: PMC9717710.
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CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment. Cell. 2021 08 19; 184(17):4512-4530.e22.
Di Pilato M, Kfuri-Rubens R, Pruessmann JN, Ozga AJ, Messemaker M, Cadilha BL, Sivakumar R, Cianciaruso C, Warner RD, Marangoni F, Carrizosa E, Lesch S, Billingsley J, Perez-Ramos D, Zavala F, Rheinbay E, Luster AD, Gerner MY, Kobold S, Pittet MJ, Mempel TR. PMID: 34343496; PMCID: PMC8719451.
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126 Fields:
Translation:
AnimalsCells
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Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4+ T cell responses. Sci Adv. 2021 07; 7(28).
Jairaman A, Othy S, Dynes JL, Yeromin AV, Zavala A, Greenberg ML, Nourse JL, Holt JR, Cahalan SM, Marangoni F, Parker I, Pathak MM, Cahalan MD. PMID: 34233878; PMCID: PMC8262815.
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32 Fields:
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AnimalsCells
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Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop. Cell. 2021 07 22; 184(15):3998-4015.e19.
Marangoni F, Zhakyp A, Corsini M, Geels SN, Carrizosa E, Thelen M, Mani V, Prüßmann JN, Warner RD, Ozga AJ, Di Pilato M, Othy S, Mempel TR. PMID: 34157302; PMCID: PMC8664158.
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PubMed Mentions:
57 Fields:
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HumansAnimalsCells
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Inhibition of CDK4/6 Promotes CD8 T-cell Memory Formation. Cancer Discov. 2021 10; 11(10):2564-2581.
Heckler M, Ali LR, Clancy-Thompson E, Qiang L, Ventre KS, Lenehan P, Roehle K, Luoma A, Boelaars K, Peters V, McCreary J, Boschert T, Wang ES, Suo S, Marangoni F, Mempel TR, Long HW, Wucherpfennig KW, Dougan M, Gray NS, Yuan GC, Goel S, Tolaney SM, Dougan SK. PMID: 33941591; PMCID: PMC8487897.
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41 Fields:
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HumansAnimalsCells
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Gene therapy for Wiskott-Aldrich syndrome: History, new vectors, future directions. J Allergy Clin Immunol. 2020 08; 146(2):262-265.
Ferrua F, Marangoni F, Aiuti A, Roncarolo MG. PMID: 32623069; PMCID: PMC7453879.
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PubMed Mentions:
14 Fields:
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HumansCells
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Cutaneous laser surgery for secondary burn reconstruction: Cost benefit analysis. Burns. 2020 05; 46(3):561-566.
Azzopardi EA, Duncan RT, Kearns M, Marangoni F, Ibrahim N, Azzopardi EAF, Boyce D, Tretti M, Mursion MSC. PMID: 31955979.
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PubMed Mentions:
2 Fields:
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Humans
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Early experience with the ATTUNE Total Knee Replacement System. Acta Biomed. 2019 10 29; 90(12-S):98-103.
Giaretta S, Berti M, Micheloni GM, Ceccato A, Marangoni F, Momoli A. PMID: 31821292; PMCID: PMC7233713.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Migratory DCs activate TGF-β to precondition naïve CD8+ T cells for tissue-resident memory fate. Science. 2019 10 11; 366(6462).
Mani V, Bromley SK, Äijö T, Mora-Buch R, Carrizosa E, Warner RD, Hamze M, Sen DR, Chasse AY, Lorant A, Griffith JW, Rahimi RA, McEntee CP, Jeffrey KL, Marangoni F, Travis MA, Lacy-Hulbert A, Luster AD, Mempel TR. PMID: 31601741; PMCID: PMC6939608.
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PubMed Mentions:
86 Fields:
Translation:
AnimalsCells
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Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer. Cell. 2019 06 27; 178(1):160-175.e27.
Ligorio M, Sil S, Malagon-Lopez J, Nieman LT, Misale S, Di Pilato M, Ebright RY, Karabacak MN, Kulkarni AS, Liu A, Vincent Jordan N, Franses JW, Philipp J, Kreuzer J, Desai N, Arora KS, Rajurkar M, Horwitz E, Neyaz A, Tai E, Magnus NKC, Vo KD, Yashaswini CN, Marangoni F, Boukhali M, Fatherree JP, Damon LJ, Xega K, Desai R, Choz M, Bersani F, Langenbucher A, Thapar V, Morris R, Wellner UF, Schilling O, Lawrence MS, Liss AS, Rivera MN, Deshpande V, Benes CH, Maheswaran S, Haber DA, Fernandez-Del-Castillo C, Ferrone CR, Haas W, Aryee MJ, Ting DT. PMID: 31155233; PMCID: PMC6697165.
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PubMed Mentions:
230 Fields:
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HumansAnimalsCells
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Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy. Nature. 2019 06; 570(7759):112-116.
Di Pilato M, Kim EY, Cadilha BL, Prüßmann JN, Nasrallah MN, Seruggia D, Usmani SM, Misale S, Zappulli V, Carrizosa E, Mani V, Ligorio M, Warner RD, Medoff BD, Marangoni F, Villani AC, Mempel TR. PMID: 31092922; PMCID: PMC6656391.
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94 Fields:
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AnimalsCells
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Guidance factors orchestrating regulatory T cell positioning in tissues during development, homeostasis, and response. Immunol Rev. 2019 05; 289(1):129-141.
Mempel TR, Marangoni F. PMID: 30977195; PMCID: PMC6499397.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Leukocyte Tracking Database, a collection of immune cell tracks from intravital 2-photon microscopy videos. Sci Data. 2018 07 17; 5:180129.
Pizzagalli DU, Farsakoglu Y, Palomino-Segura M, Palladino E, Sintes J, Marangoni F, Mempel TR, Koh WH, Murooka TT, Thelen F, Stein JV, Pozzi G, Thelen M, Krause R, Gonzalez SF. PMID: 30015806; PMCID: PMC6049032.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Tumor Tolerance-Promoting Function of Regulatory T Cells Is Optimized by CD28, but Strictly Dependent on Calcineurin. J Immunol. 2018 05 15; 200(10):3647-3661.
Marangoni F, Zhang R, Mani V, Thelen M, Ali Akbar NJ, Warner RD, Äijö T, Zappulli V, Martinez GJ, Turka LA, Mempel TR. PMID: 29661826; PMCID: PMC5940497.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Correction: B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells. J Immunol. 2018 04 01; 200(7):2505-2506.
Zhang R, Sage PT, Finn K, Huynh A, Blazar BR, Marangoni F, Mempel TR, Sharpe AH, Turka LA. PMID: 29475985.
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Autonomous role of Wiskott-Aldrich syndrome platelet deficiency in inducing autoimmunity and inflammation. J Allergy Clin Immunol. 2018 10; 142(4):1272-1284.
Sereni L, Castiello MC, Marangoni F, Anselmo A, di Silvestre D, Motta S, Draghici E, Mantero S, Thrasher AJ, Giliani S, Aiuti A, Mauri P, Notarangelo LD, Bosticardo M, Villa A. PMID: 29421274; PMCID: PMC6078823.
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16 Fields:
Translation:
HumansAnimalsCells
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B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells. J Immunol. 2017 12 15; 199(12):3972-3980.
Zhang R, Sage PT, Finn K, Huynh A, Blazar BR, Marangoni F, Mempel TR, Sharpe AH, Turka LA. PMID: 29093061; PMCID: PMC5716898.
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12 Fields:
Translation:
AnimalsCells
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Corrigendum to "Evidence for Long-term Efficacy and Safety of Gene Therapy for Wiskott-Aldrich Syndrome in Preclinical Models". Mol Ther. 2009 Jul; 17(7):1300.
Marangoni F, Bosticardo M, Charrier S, Draghici E, Locci M, Scaramuzza S, Panaroni C, Ponzoni M, Sanvito F, Doglioni C, Liabeuf M, Gjata B, Montus M, Siminovitch K, Aiuti A, Naldini L, Dupré L, Roncarolo MG, Galy A, Villa A. PMID: 28178476; PMCID: PMC2835200.
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1 Fields:
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The cell division control protein 42-Src family kinase-neural Wiskott-Aldrich syndrome protein pathway regulates human proplatelet formation. J Thromb Haemost. 2016 12; 14(12):2524-2535.
Palazzo A, Bluteau O, Messaoudi K, Marangoni F, Chang Y, Souquere S, Pierron G, Lapierre V, Zheng Y, Vainchenker W, Raslova H, Debili N. PMID: 27685868.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells. Immunity. 2015 Feb 17; 42(2):265-278.
Martinez GJ, Pereira RM, Äijö T, Kim EY, Marangoni F, Pipkin ME, Togher S, Heissmeyer V, Zhang YC, Crotty S, Lamperti ED, Ansel KM, Mempel TR, Lähdesmäki H, Hogan PG, Rao A. PMID: 25680272; PMCID: PMC4346317.
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PubMed Mentions:
380 Fields:
Translation:
AnimalsCells
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Dynamic Treg interactions with intratumoral APCs promote local CTL dysfunction. J Clin Invest. 2014 Jun; 124(6):2425-40.
Bauer CA, Kim EY, Marangoni F, Carrizosa E, Claudio NM, Mempel TR. PMID: 24812664; PMCID: PMC4089459.
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PubMed Mentions:
120 Fields:
Translation:
AnimalsCells
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The transcription factor NFAT exhibits signal memory during serial T cell interactions with antigen-presenting cells. Immunity. 2013 Feb 21; 38(2):237-49.
Marangoni F, Murooka TT, Manzo T, Kim EY, Carrizosa E, Elpek NM, Mempel TR. PMID: 23313588; PMCID: PMC3582823.
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PubMed Mentions:
87 Fields:
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HumansAnimalsCells
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HIV-infected T cells are migratory vehicles for viral dissemination. Nature. 2012 Oct 11; 490(7419):283-7.
Murooka TT, Deruaz M, Marangoni F, Vrbanac VD, Seung E, von Andrian UH, Tager AM, Luster AD, Mempel TR. PMID: 22854780; PMCID: PMC3470742.
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PubMed Mentions:
204 Fields:
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HumansAnimalsCells
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Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: analysis of function and distribution in lymphoid organs. J Allergy Clin Immunol. 2010 Feb; 125(2):439-448.e8.
Trifari S, Scaramuzza S, Catucci M, Ponzoni M, Mollica L, Chiesa R, Cattaneo F, Lafouresse F, Calvez R, Vermi W, Medicina D, Castiello MC, Marangoni F, Bosticardo M, Doglioni C, Caniglia M, Aiuti A, Villa A, Roncarolo MG, Dupré L. PMID: 20159256.
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18 Fields:
Translation:
HumansCells
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Recent advances in understanding the pathophysiology of Wiskott-Aldrich syndrome. Blood. 2009 Jun 18; 113(25):6288-95.
Bosticardo M, Marangoni F, Aiuti A, Villa A, Grazia Roncarolo M. PMID: 19351959.
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91 Fields:
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HumansAnimalsCells
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The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function. J Exp Med. 2009 Apr 13; 206(4):735-42.
Locci M, Draghici E, Marangoni F, Bosticardo M, Catucci M, Aiuti A, Cancrini C, Marodi L, Espanol T, Bredius RG, Thrasher AJ, Schulz A, Litzman J, Roncarolo MG, Casorati G, Dellabona P, Villa A. PMID: 19307326; PMCID: PMC2715111.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models. Mol Ther. 2009 06; 17(6):1073-82.
Marangoni F, Bosticardo M, Charrier S, Draghici E, Locci M, Scaramuzza S, Panaroni C, Ponzoni M, Sanvito F, Doglioni C, Liabeuf M, Gjata B, Montus M, Siminovitch K, Aiuti A, Naldini L, Dupré L, Roncarolo MG, Galy A, Villa A. PMID: 19259069; PMCID: PMC2835187.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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CD44 keeps tumor killers polarized. Immunity. 2008 Dec 19; 29(6):843-5.
Mempel TR, Marangoni F. PMID: 19100697.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Maternal smoking habits are associated with differences in infants' long-chain polyunsaturated fatty acids in whole blood: a case-control study. Arch Dis Child. 2008 May; 93(5):414-8.
Agostoni C, Riva E, Giovannini M, Pinto F, Colombo C, Risé P, Galli C, Marangoni F. PMID: 18426936.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Current understanding of the Wiskott-Aldrich syndrome and prospects for gene therapy. Expert Rev Clin Immunol. 2007 Mar; 3(2):205-15.
Trifari S, Marangoni F, Scaramuzza S, Aiuti A, Roncarolo MG, Dupré L. PMID: 20477109.
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WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells. J Exp Med. 2007 Feb 19; 204(2):369-80.
Marangoni F, Trifari S, Scaramuzza S, Panaroni C, Martino S, Notarangelo LD, Baz Z, Metin A, Cattaneo F, Villa A, Aiuti A, Battaglia M, Roncarolo MG, Dupré L. PMID: 17296785; PMCID: PMC2118740.
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PubMed Mentions:
78 Fields:
Translation:
HumansAnimalsCells
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Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients. J Immunol. 2006 Nov 15; 177(10):7451-61.
Trifari S, Sitia G, Aiuti A, Scaramuzza S, Marangoni F, Guidotti LG, Martino S, Saracco P, Notarangelo LD, Roncarolo MG, Dupré L. PMID: 17082665.
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PubMed Mentions:
53 Fields:
Translation:
HumansCells
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Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation. Hum Gene Ther. 2006 Mar; 17(3):303-13.
Dupré L, Marangoni F, Scaramuzza S, Trifari S, Hernández RJ, Aiuti A, Naldini L, Roncarolo MG. PMID: 16544979.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Lentiviral vector-mediated gene transfer in T cells from Wiskott-Aldrich syndrome patients leads to functional correction. Mol Ther. 2004 Nov; 10(5):903-15.
Dupré L, Trifari S, Follenzi A, Marangoni F, Lain de Lera T, Bernad A, Martino S, Tsuchiya S, Bordignon C, Naldini L, Aiuti A, Roncarolo MG. PMID: 15509508.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Prevention of HER-2/neu transgenic mammary carcinoma by tamoxifen plus interleukin 12. Int J Cancer. 2003 Jun 20; 105(3):384-9.
Nanni P, Nicoletti G, De Giovanni C, Landuzzi L, Di Carlo E, Iezzi M, Ricci C, Astolfi A, Croci S, Marangoni F, Musiani P, Forni G, Lollini PL. PMID: 12704673.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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Plasma arachidonic acid and serum thromboxane B2 concentrations in phenylketonuric children are correlated with dietary compliance. Z Ernahrungswiss. 1998; 37 Suppl 1:122-4.
Agostoni C, Riva E, Galli C, Marangoni F, Luotti D, Giovannini M. PMID: 9558743.
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Humans
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Plasma arachidonic acid and serum thromboxane B2 concentrations in phenylketonuric children negatively correlate with dietary compliance. Prostaglandins Leukot Essent Fatty Acids. 1997 Mar; 56(3):219-22.
Agostoni C, Marangoni F, Riva E, Giovannini M, Galli C. PMID: 9089802.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells