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Cholsoon Jang

Title(s)Assistant Professor, Biological Chemistry
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-6052
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. mTORC1 promotes cell growth via m6A-dependent mRNA degradation. Mol Cell. 2021 Mar 19. Cho S, Lee G, Pickering BF, Jang C, Park JH, He L, Mathur L, Kim SS, Jung S, Tang HW, Monette S, Rabinowitz JD, Perrimon N, Jaffrey SR, Blenis J. PMID: 33756105.
      View in: PubMed   Mentions:    Fields:    
    2. Comprehensive quantification of fuel use by the failing and nonfailing human heart. Science. 2020 10 16; 370(6514):364-368. Murashige D, Jang C, Neinast M, Edwards JJ, Cowan A, Hyman MC, Rabinowitz JD, Frankel DS, Arany Z. PMID: 33060364.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Quantitative Fluxomics of Circulating Metabolites. Cell Metab. 2020 Oct 06; 32(4):676-688.e4. Hui S, Cowan AJ, Zeng X, Yang L, TeSlaa T, Li X, Bartman C, Zhang Z, Jang C, Wang L, Lu W, Rojas J, Baur J, Rabinowitz JD. PMID: 32791100.
      View in: PubMed   Mentions: 1     Fields:    
    4. The hepatocyte clock and feeding control chronophysiology of multiple liver cell types. Science. 2020 09 11; 369(6509):1388-1394. Guan D, Xiong Y, Trinh TM, Xiao Y, Hu W, Jiang C, Dierickx P, Jang C, Rabinowitz JD, Lazar MA. PMID: 32732282.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. The small intestine shields the liver from fructose-induced steatosis. Nat Metab. 2020 07; 2(7):586-593. Jang C, Wada S, Yang S, Gosis B, Zeng X, Zhang Z, Shen Y, Lee G, Arany Z, Rabinowitz JD. PMID: 32694791.
      View in: PubMed   Mentions:
    6. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 2020 03; 579(7800):586-591. Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller KD, Schug ZT, Snyder NW, Gade TP, Titchenell PM, Rabinowitz JD, Wellen KE. PMID: 32214246.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    7. Serine Catabolism Feeds NADH when Respiration Is Impaired. Cell Metab. 2020 Apr 07; 31(4):809-821.e6. Yang L, Garcia Canaveras JC, Chen Z, Wang L, Liang L, Jang C, Mayr JA, Zhang Z, Ghergurovich JM, Zhan L, Joshi S, Hu Z, McReynolds MR, Su X, White E, Morscher RJ, Rabinowitz JD. PMID: 32187526.
      View in: PubMed   Mentions: 7     Fields:    
    8. Effect of Interleukin-15 Receptor Alpha Ablation on the Metabolic Responses to Moderate Exercise Simulated by in vivo Isometric Muscle Contractions. Front Physiol. 2019; 10:1439. Loro E, Jang C, Quinn WJ, Baur JA, Arany ZP, Khurana TS. PMID: 31849697.
      View in: PubMed   Mentions:
    9. Metabolite Exchange between Mammalian Organs Quantified in Pigs. Cell Metab. 2019 09 03; 30(3):594-606.e3. Jang C, Hui S, Zeng X, Cowan AJ, Wang L, Chen L, Morscher RJ, Reyes J, Frezza C, Hwang HY, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, Zsido GA, Gorman JH, Gorman RC, Rabinowitz JD. PMID: 31257152.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    10. Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. Cell Metab. 2019 02 05; 29(2):417-429.e4. Neinast MD, Jang C, Hui S, Murashige DS, Chu Q, Morscher RJ, Li X, Zhan L, White E, Anthony TG, Rabinowitz JD, Arany Z. PMID: 30449684.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    11. Endothelial pyruvate kinase M2 maintains vascular integrity. J Clin Invest. 2018 10 01; 128(10):4543-4556. Kim B, Jang C, Dharaneeswaran H, Li J, Bhide M, Yang S, Li K, Arany Z. PMID: 30222136.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    12. Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes. Cell. 2018 08 09; 174(4):831-842.e12. Guan D, Xiong Y, Borck PC, Jang C, Doulias PT, Papazyan R, Fang B, Jiang C, Zhang Y, Briggs ER, Hu W, Steger D, Ischiropoulos H, Rabinowitz JD, Lazar MA. PMID: 30057115.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    13. Fructose metabolism, cardiometabolic risk, and the epidemic of coronary artery disease. Eur Heart J. 2018 07 07; 39(26):2497-2505. Mirtschink P, Jang C, Arany Z, Krek W. PMID: 29020416.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    14. Metabolomics and Isotope Tracing. Cell. 2018 05 03; 173(4):822-837. Jang C, Chen L, Rabinowitz JD. PMID: 29727671.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    15. Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice. J Clin Invest. 2018 06 01; 128(6):2226-2238. Lanaspa MA, Andres-Hernando A, Orlicky DJ, Cicerchi C, Jang C, Li N, Milagres T, Kuwabara M, Wempe MF, Rabinowitz JD, Johnson RJ, Tolan DR. PMID: 29533924.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    16. The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids. Cell Metab. 2018 02 06; 27(2):351-361.e3. Jang C, Hui S, Lu W, Cowan AJ, Morscher RJ, Lee G, Liu W, Tesz GJ, Birnbaum MJ, Rabinowitz JD. PMID: 29414685.
      View in: PubMed   Mentions: 59     Fields:    Translation:Animals
    17. Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling. Cell. 2017 Dec 14; 171(7):1545-1558.e18. Lee G, Zheng Y, Cho S, Jang C, England C, Dempsey JM, Yu Y, Liu X, He L, Cavaliere PM, Chavez A, Zhang E, Isik M, Couvillon A, Dephoure NE, Blackwell TK, Yu JJ, Rabinowitz JD, Cantley LC, Blenis J. PMID: 29153836.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    18. Glucose feeds the TCA cycle via circulating lactate. Nature. 2017 11 02; 551(7678):115-118. Hui S, Ghergurovich JM, Morscher RJ, Jang C, Teng X, Lu W, Esparza LA, Reya T, Le Zhan , Yanxiang Guo J, White E, Rabinowitz JD. PMID: 29045397.
      View in: PubMed   Mentions: 164     Fields:    Translation:AnimalsCells
    19. PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy. Circ Res. 2017 Dec 08; 121(12):1370-1378. Liu LX, Rowe GC, Yang S, Li J, Damilano F, Chan MC, Lu W, Jang C, Wada S, Morley M, Hesse M, Fleischmann BK, Rabinowitz JD, Das S, Rosenzweig A, Arany Z. PMID: 28928113.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    20. Glutamine fuels proliferation but not migration of endothelial cells. EMBO J. 2017 08 15; 36(16):2321-2333. Kim B, Li J, Jang C, Arany Z. PMID: 28659379.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    21. The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue. Genes Dev. 2016 11 15; 30(22):2551-2564. Wada S, Neinast M, Jang C, Ibrahim YH, Lee G, Babu A, Li J, Hoshino A, Rowe GC, Rhee J, Martina JA, Puertollano R, Blenis J, Morley M, Baur JA, Seale P, Arany Z. PMID: 27913603.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    22. A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. Nat Med. 2016 Apr; 22(4):421-6. Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z. PMID: 26950361.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimals
    23. Mitochondria Cripple without Krüppel. Trends Endocrinol Metab. 2015 Nov; 26(11):587-589. Jang C, Arany Z. PMID: 26404663.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    24. PGC-1a induces SPP1 to activate macrophages and orchestrate functional angiogenesis in skeletal muscle. Circ Res. 2014 Aug 15; 115(5):504-17. Rowe GC, Raghuram S, Jang C, Nagy JA, Patten IS, Goyal A, Chan MC, Liu LX, Jiang A, Spokes KC, Beeler D, Dvorak H, Aird WC, Arany Z. PMID: 25009290.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    25. Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by truncated peroxisome proliferator-activated receptor ? coactivator (PGC)-1a. J Biol Chem. 2014 Mar 28; 289(13):8810-7. Thom R, Rowe GC, Jang C, Safdar A, Arany Z. PMID: 24505137.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    26. WITHDRAWN: Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by N-Terminus Peroxisome Proliferator-Activated Receptor Gamma Coactivator (NT-PGC)-1alpha. J Biol Chem. 2014 Jan 15. Thom R, Rowe GC, Jang C, Safdar A, White JP, Arany Z. PMID: 24398674.
      View in: PubMed   Mentions:    Fields:    
    27. Metabolism: Sweet enticements to move. Nature. 2013 Aug 22; 500(7463):409-11. Jang C, Arany Z. PMID: 23945589.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    28. Cardiac angiogenic imbalance leads to peripartum cardiomyopathy. Nature. 2012 May 09; 485(7398):333-8. Patten IS, Rana S, Shahul S, Rowe GC, Jang C, Liu L, Hacker MR, Rhee JS, Mitchell J, Mahmood F, Hess P, Farrell C, Koulisis N, Khankin EV, Burke SD, Tudorache I, Bauersachs J, del Monte F, Hilfiker-Kleiner D, Karumanchi SA, Arany Z. PMID: 22596155.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimalsCells
    29. UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila. Dev Biol. 2011 Aug 15; 356(2):588-97. Lee G, Liang C, Park G, Jang C, Jung JU, Chung J. PMID: 21729695.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    30. PGC-1ß regulates angiogenesis in skeletal muscle. Am J Physiol Endocrinol Metab. 2011 Jul; 301(1):E155-63. Rowe GC, Jang C, Patten IS, Arany Z. PMID: 21364124.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    31. Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice. Diabetes. 2009 Apr; 58(4):965-74. Hwang JH, Kim DW, Jo EJ, Kim YK, Jo YS, Park JH, Yoo SK, Park MK, Kwak TH, Kho YL, Han J, Choi HS, Lee SH, Kim JM, Lee I, Kyung T, Jang C, Chung J, Kweon GR, Shong M. PMID: 19136651.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    32. LKB1 induces apical trafficking of Silnoon, a monocarboxylate transporter, in Drosophila melanogaster. J Cell Biol. 2008 Oct 06; 183(1):11-7. Jang C, Lee G, Chung J. PMID: 18838551.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
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