Cholsoon Jang

Title(s)Assistant Professor, Biological Chemistry
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-6052
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Global Microbiota-Dependent Histone Acetylation Patterns are Irreversible and Independent of Short Chain Fatty Acids. Hepatology. 2021 Jul 07. Saiman Y, Shen TD, Lund PJ, Gershuni VM, Jang C, Patel S, Jung S, Furth EE, Friedman ES, Chau L, Garcia BA, Wu GD. PMID: 34233020.
      View in: PubMed   Mentions:    Fields:    
    2. Glucagon regulates the stability of REV-ERBa to modulate hepatic glucose production in a model of lung cancer-associated cachexia. Sci Adv. 2021 Jun; 7(26). Verlande A, Chun SK, Goodson MO, Fortin BM, Bae H, Jang C, Masri S. PMID: 34172439.
      View in: PubMed   Mentions:    Fields:    
    3. Disparate Metabolomic Responses to Fructose Consumption between Different Mouse Strains and the Role of Gut Microbiota. Metabolites. 2021 May 26; 11(6). Ahn IS, Yoon J, Diamante G, Cohn P, Jang C, Yang X. PMID: 34073358.
      View in: PubMed   Mentions:
    4. The interaction between the gut microbiota and dietary carbohydrates in nonalcoholic fatty liver disease. Exp Mol Med. 2021 May 20. Park G, Jung S, Wellen KE, Jang C. PMID: 34017059.
      View in: PubMed   Mentions:    Fields:    
    5. The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine. Cell Metab. 2021 Apr 16. Yu D, Richardson NE, Green CL, Spicer AB, Murphy ME, Flores V, Jang C, Kasza I, Nikodemova M, Wakai MH, Tomasiewicz JL, Yang SE, Miller BR, Pak HH, Brinkman JA, Rojas JM, Quinn WJ, Cheng EP, Konon EN, Haider LR, Finke M, Sonsalla M, Alexander CM, Rabinowitz JD, Baur JA, Malecki KC, Lamming DW. PMID: 33887198.
      View in: PubMed   Mentions: 2     Fields:    
    6. 13C Metabolic Flux Analysis Indicates Endothelial Cells Attenuate Metabolic Perturbations by Modulating TCA Activity. Metabolites. 2021 Apr 07; 11(4). Moiz B, Garcia J, Basehore S, Sun A, Li A, Padmanabhan S, Albus K, Jang C, Sriram G, Clyne AM. PMID: 33917224.
      View in: PubMed   Mentions:
    7. mTORC1 promotes cell growth via m6A-dependent mRNA degradation. Mol Cell. 2021 05 20; 81(10):2064-2075.e8. Cho S, Lee G, Pickering BF, Jang C, Park JH, He L, Mathur L, Kim SS, Jung S, Tang HW, Monette S, Rabinowitz JD, Perrimon N, Jaffrey SR, Blenis J. PMID: 33756105.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    8. Organismal Fructose Metabolism in Health and Non-Alcoholic Fatty Liver Disease. Biology (Basel). 2020 Nov 18; 9(11). Skenderian S, Park G, Jang C. PMID: 33218081.
      View in: PubMed   Mentions:
    9. Comprehensive quantification of fuel use by the failing and nonfailing human heart. Science. 2020 10 16; 370(6514):364-368. Murashige D, Jang C, Neinast M, Edwards JJ, Cowan A, Hyman MC, Rabinowitz JD, Frankel DS, Arany Z. PMID: 33060364.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    10. Quantitative Fluxomics of Circulating Metabolites. Cell Metab. 2020 10 06; 32(4):676-688.e4. Hui S, Cowan AJ, Zeng X, Yang L, TeSlaa T, Li X, Bartman C, Zhang Z, Jang C, Wang L, Lu W, Rojas J, Baur J, Rabinowitz JD. PMID: 32791100.
      View in: PubMed   Mentions: 15     Fields:    
    11. The hepatocyte clock and feeding control chronophysiology of multiple liver cell types. Science. 2020 09 11; 369(6509):1388-1394. Guan D, Xiong Y, Trinh TM, Xiao Y, Hu W, Jiang C, Dierickx P, Jang C, Rabinowitz JD, Lazar MA. PMID: 32732282.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    12. The small intestine shields the liver from fructose-induced steatosis. Nat Metab. 2020 07; 2(7):586-593. Jang C, Wada S, Yang S, Gosis B, Zeng X, Zhang Z, Shen Y, Lee G, Arany Z, Rabinowitz JD. PMID: 32694791.
      View in: PubMed   Mentions:
    13. Angiopoietin-2-integrin a5ß1 signaling enhances vascular fatty acid transport and prevents ectopic lipid-induced insulin resistance. Nat Commun. 2020 06 12; 11(1):2980. Bae H, Hong KY, Lee CK, Jang C, Lee SJ, Choe K, Offermanns S, He Y, Lee HJ, Koh GY. PMID: 32532986.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    14. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 2020 03; 579(7800):586-591. Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller KD, Schug ZT, Snyder NW, Gade TP, Titchenell PM, Rabinowitz JD, Wellen KE. PMID: 32214246.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    15. Serine Catabolism Feeds NADH when Respiration Is Impaired. Cell Metab. 2020 04 07; 31(4):809-821.e6. Yang L, Garcia Canaveras JC, Chen Z, Wang L, Liang L, Jang C, Mayr JA, Zhang Z, Ghergurovich JM, Zhan L, Joshi S, Hu Z, McReynolds MR, Su X, White E, Morscher RJ, Rabinowitz JD. PMID: 32187526.
      View in: PubMed   Mentions: 21     Fields:    
    16. Effect of Interleukin-15 Receptor Alpha Ablation on the Metabolic Responses to Moderate Exercise Simulated by in vivo Isometric Muscle Contractions. Front Physiol. 2019; 10:1439. Loro E, Jang C, Quinn WJ, Baur JA, Arany ZP, Khurana TS. PMID: 31849697.
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    17. Metabolite Exchange between Mammalian Organs Quantified in Pigs. Cell Metab. 2019 09 03; 30(3):594-606.e3. Jang C, Hui S, Zeng X, Cowan AJ, Wang L, Chen L, Morscher RJ, Reyes J, Frezza C, Hwang HY, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, Zsido GA, Gorman JH, Gorman RC, Rabinowitz JD. PMID: 31257152.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    18. Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation. Science. 2019 02 08; 363(6427):644-649. Lee CK, Jeong SH, Jang C, Bae H, Kim YH, Park I, Kim SK, Koh GY. PMID: 30733421.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    19. Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. Cell Metab. 2019 02 05; 29(2):417-429.e4. Neinast MD, Jang C, Hui S, Murashige DS, Chu Q, Morscher RJ, Li X, Zhan L, White E, Anthony TG, Rabinowitz JD, Arany Z. PMID: 30449684.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    20. Endothelial pyruvate kinase M2 maintains vascular integrity. J Clin Invest. 2018 10 01; 128(10):4543-4556. Kim B, Jang C, Dharaneeswaran H, Li J, Bhide M, Yang S, Li K, Arany Z. PMID: 30222136.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    21. Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes. Cell. 2018 08 09; 174(4):831-842.e12. Guan D, Xiong Y, Borck PC, Jang C, Doulias PT, Papazyan R, Fang B, Jiang C, Zhang Y, Briggs ER, Hu W, Steger D, Ischiropoulos H, Rabinowitz JD, Lazar MA. PMID: 30057115.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    22. Fructose metabolism, cardiometabolic risk, and the epidemic of coronary artery disease. Eur Heart J. 2018 07 07; 39(26):2497-2505. Mirtschink P, Jang C, Arany Z, Krek W. PMID: 29020416.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansPHPublic Health
    23. Metabolomics and Isotope Tracing. Cell. 2018 05 03; 173(4):822-837. Jang C, Chen L, Rabinowitz JD. PMID: 29727671.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCells
    24. Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice. J Clin Invest. 2018 06 01; 128(6):2226-2238. Lanaspa MA, Andres-Hernando A, Orlicky DJ, Cicerchi C, Jang C, Li N, Milagres T, Kuwabara M, Wempe MF, Rabinowitz JD, Johnson RJ, Tolan DR. PMID: 29533924.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    25. The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids. Cell Metab. 2018 02 06; 27(2):351-361.e3. Jang C, Hui S, Lu W, Cowan AJ, Morscher RJ, Lee G, Liu W, Tesz GJ, Birnbaum MJ, Rabinowitz JD. PMID: 29414685.
      View in: PubMed   Mentions: 108     Fields:    Translation:Animals
    26. Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling. Cell. 2017 Dec 14; 171(7):1545-1558.e18. Lee G, Zheng Y, Cho S, Jang C, England C, Dempsey JM, Yu Y, Liu X, He L, Cavaliere PM, Chavez A, Zhang E, Isik M, Couvillon A, Dephoure NE, Blackwell TK, Yu JJ, Rabinowitz JD, Cantley LC, Blenis J. PMID: 29153836.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    27. Glucose feeds the TCA cycle via circulating lactate. Nature. 2017 11 02; 551(7678):115-118. Hui S, Ghergurovich JM, Morscher RJ, Jang C, Teng X, Lu W, Esparza LA, Reya T, Le Zhan , Yanxiang Guo J, White E, Rabinowitz JD. PMID: 29045397.
      View in: PubMed   Mentions: 268     Fields:    Translation:AnimalsCells
    28. PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy. Circ Res. 2017 Dec 08; 121(12):1370-1378. Liu LX, Rowe GC, Yang S, Li J, Damilano F, Chan MC, Lu W, Jang C, Wada S, Morley M, Hesse M, Fleischmann BK, Rabinowitz JD, Das S, Rosenzweig A, Arany Z. PMID: 28928113.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    29. Glutamine fuels proliferation but not migration of endothelial cells. EMBO J. 2017 08 15; 36(16):2321-2333. Kim B, Li J, Jang C, Arany Z. PMID: 28659379.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    30. The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue. Genes Dev. 2016 11 15; 30(22):2551-2564. Wada S, Neinast M, Jang C, Ibrahim YH, Lee G, Babu A, Li J, Hoshino A, Rowe GC, Rhee J, Martina JA, Puertollano R, Blenis J, Morley M, Baur JA, Seale P, Arany Z. PMID: 27913603.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    31. A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. Nat Med. 2016 Apr; 22(4):421-6. Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z. PMID: 26950361.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansAnimals
    32. Mitochondria Cripple without Krüppel. Trends Endocrinol Metab. 2015 Nov; 26(11):587-589. Jang C, Arany Z. PMID: 26404663.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    33. PGC-1a induces SPP1 to activate macrophages and orchestrate functional angiogenesis in skeletal muscle. Circ Res. 2014 Aug 15; 115(5):504-17. Rowe GC, Raghuram S, Jang C, Nagy JA, Patten IS, Goyal A, Chan MC, Liu LX, Jiang A, Spokes KC, Beeler D, Dvorak H, Aird WC, Arany Z. PMID: 25009290.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    34. Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by truncated peroxisome proliferator-activated receptor ? coactivator (PGC)-1a. J Biol Chem. 2014 Mar 28; 289(13):8810-7. Thom R, Rowe GC, Jang C, Safdar A, Arany Z. PMID: 24505137.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    35. WITHDRAWN: Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by N-Terminus Peroxisome Proliferator-Activated Receptor Gamma Coactivator (NT-PGC)-1alpha. J Biol Chem. 2014 Jan 15. Thom R, Rowe GC, Jang C, Safdar A, White JP, Arany Z. PMID: 24398674.
      View in: PubMed   Mentions:    Fields:    
    36. Metabolism: Sweet enticements to move. Nature. 2013 Aug 22; 500(7463):409-11. Jang C, Arany Z. PMID: 23945589.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    37. Cardiac angiogenic imbalance leads to peripartum cardiomyopathy. Nature. 2012 May 09; 485(7398):333-8. Patten IS, Rana S, Shahul S, Rowe GC, Jang C, Liu L, Hacker MR, Rhee JS, Mitchell J, Mahmood F, Hess P, Farrell C, Koulisis N, Khankin EV, Burke SD, Tudorache I, Bauersachs J, del Monte F, Hilfiker-Kleiner D, Karumanchi SA, Arany Z. PMID: 22596155.
      View in: PubMed   Mentions: 141     Fields:    Translation:HumansAnimalsCells
    38. UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila. Dev Biol. 2011 Aug 15; 356(2):588-97. Lee G, Liang C, Park G, Jang C, Jung JU, Chung J. PMID: 21729695.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    39. PGC-1ß regulates angiogenesis in skeletal muscle. Am J Physiol Endocrinol Metab. 2011 Jul; 301(1):E155-63. Rowe GC, Jang C, Patten IS, Arany Z. PMID: 21364124.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    40. Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice. Diabetes. 2009 Apr; 58(4):965-74. Hwang JH, Kim DW, Jo EJ, Kim YK, Jo YS, Park JH, Yoo SK, Park MK, Kwak TH, Kho YL, Han J, Choi HS, Lee SH, Kim JM, Lee I, Kyung T, Jang C, Chung J, Kweon GR, Shong M. PMID: 19136651.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    41. LKB1 induces apical trafficking of Silnoon, a monocarboxylate transporter, in Drosophila melanogaster. J Cell Biol. 2008 Oct 06; 183(1):11-7. Jang C, Lee G, Chung J. PMID: 18838551.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
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