Edward L Nelson

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-5153
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    Neoadjuvant photodynamic immunomodulation for colon cancer
    NIH R21CA153594Aug 1, 2010 - Jul 31, 2013
    Role: Principal Investigator
    Application of a Novel Nanotechnology for Molecular Profiling of Tumor Cellular E
    NIH R21CA132039Jun 20, 2008 - Apr 30, 2011
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A Therapeutic Vaccine Targeting Rat BORIS (CTCFL) for the Treatment of Rat Breast Cancer Tumors. Int J Mol Sci. 2023 Mar 22; 24(6). Loukinov D, Anderson AL, Mkrtichyan M, Ghochikyan A, Rivero-Hinojosa S, Tucker J, Lobanenkov V, Agadjanyan MG, Nelson EL. PMID: 36983050; PMCID: PMC10058450.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    2. Nanoparticle vaccines can be designed to induce pDC support of mDCs for increased antigen display. Biomater Sci. 2023 Jan 17; 11(2):596-610. Butkovich N, Tucker JA, Ramirez A, Li E, Meli VS, Nelson EL, Wang SW. PMID: 36476811; PMCID: PMC10775882.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. Evaluating Anti-tumor Immune Responses of Protein Nanoparticle-Based Cancer Vaccines. Methods Mol Biol. 2023; 2671:321-333. Li E, Butkovich N, Tucker JA, Nelson EL, Wang SW. PMID: 37308653; PMCID: PMC10560535.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    4. Macromolecular assembly of bioluminescent protein nanoparticles for enhanced imaging. Mater Today Bio. 2022 Dec 15; 17:100455. Li E, Brennan CK, Ramirez A, Tucker JA, Butkovich N, Meli VS, Ionkina AA, Nelson EL, Prescher JA, Wang SW. PMID: 36304975; PMCID: PMC9593766.
      View in: PubMed   Mentions: 1  
    5. Adoptive T-Cell Therapy in Advanced Colorectal Cancer: A Systematic Review. Oncologist. 2022 03 11; 27(3):210-219. Juat DJ, Hachey SJ, Billimek J, Del Rosario MP, Nelson EL, Hughes CCW, Zell JA. PMID: 35274719; PMCID: PMC8914488.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    6. Immunological and psychosocial functioning in parents of children with cancer. Support Care Cancer. 2022 Apr; 30(4):3379-3388. Agbayani CJ, Tucker JA, Nelson EL, Martinez F, Cortes H, Khoury D, Kain ZN, Lin C, Torno L, Fortier MA. PMID: 34994860.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Longitudinal Changes in Sleep: Associations with Shifts in Circulating Cytokines and Emotional Distress in a Cancer Survivor Population. Int J Behav Med. 2021 Feb; 28(1):140-150. Tucker JA, Osann K, Hsieh S, Wahi A, Monk BJ, Wenzel L, Nelson EL. PMID: 33598780; PMCID: PMC7925505.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. An Antigen-Delivery Protein Nanoparticle Combined with Anti-PD-1 Checkpoint Inhibitor Has Curative Efficacy in an Aggressive Melanoma Model. Adv Ther (Weinh). 2020 Dec; 3(12). Neek M, Tucker JA, Butkovich N, Nelson EL, Wang SW. PMID: 34141865; PMCID: PMC8205422.
      View in: PubMed   Mentions: 7  
    9. Metabolite Responsive Nanoparticle-Protein Complex. Biomacromolecules. 2019 07 08; 20(7):2703-2712. Fruehauf KR, Kim TI, Nelson EL, Patterson JP, Wang SW, Shea KJ. PMID: 31117354; PMCID: PMC7819679.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    10. Relationship between social support, quality of life, and Th2 cytokines in a biobehavioral cancer survivorship trial. Support Care Cancer. 2019 Sep; 27(9):3301-3310. Osann K, Wilford J, Wenzel L, Hsieh S, Tucker JA, Wahi A, Monk BJ, Nelson EL. PMID: 30612237; PMCID: PMC6612537.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Microfluidic filter device with nylon mesh membranes efficiently dissociates cell aggregates and digested tissue into single cells. Lab Chip. 2018 09 11; 18(18):2776-2786. Qiu X, Lombardo JA, Westerhof TM, Pennell M, Ng A, Alshetaiwi H, Luna BM, Nelson EL, Kessenbrock K, Hui EE, Haun JB. PMID: 30090895; PMCID: PMC6171522.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    12. Anticancer Mechanisms in Two Murine Bone Marrow-Derived Dendritic Cell Subsets Activated with TLR4 Agonists. J Immunol. 2018 04 15; 200(8):2656-2669. Bagaev A, Pichugin A, Nelson EL, Agadjanyan MG, Ghochikyan A, Ataullakhanov RI. PMID: 29500244; PMCID: PMC5962282.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    13. Microfluidic channel optimization to improve hydrodynamic dissociation of cell aggregates and tissue. Sci Rep. 2018 02 09; 8(1):2774. Qiu X, Huang JH, Westerhof TM, Lombardo JA, Henrikson KM, Pennell M, Pourfard PP, Nelson EL, Nath P, Haun JB. PMID: 29426941; PMCID: PMC5807353.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    14. Co-delivery of human cancer-testis antigens with adjuvant in protein nanoparticles induces higher cell-mediated immune responses. Biomaterials. 2018 02; 156:194-203. Neek M, Tucker JA, Kim TI, Molino NM, Nelson EL, Wang SW. PMID: 29202325; PMCID: PMC5783197.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    15. Highly efficient cellular cloning using Ferro-core Micropallet Arrays. Sci Rep. 2017 10 12; 7(1):13081. Westerhof TM, Cox-Muranami WA, Li GP, Bachman M, Fan H, Nelson EL. PMID: 29026113; PMCID: PMC5638909.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    16. Microfluidic device for rapid digestion of tissues into cellular suspensions. Lab Chip. 2017 09 26; 17(19):3300-3309. Qiu X, Westerhof TM, Karunaratne AA, Werner EM, Pourfard PP, Nelson EL, Hui EE, Haun JB. PMID: 28850139; PMCID: PMC5614870.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    17. A hybrid resistive pulse-optical detection platform for microfluidic experiments. Sci Rep. 2017 08 31; 7(1):10173. Hinkle P, Westerhof TM, Qiu Y, Mallin DJ, Wallace ML, Nelson EL, Taborek P, Siwy ZS. PMID: 28860641; PMCID: PMC5579027.
      View in: PubMed   Mentions: 1     Fields:    
    18. Display of DNA on Nanoparticles for Targeting Antigen Presenting Cells. ACS Biomater Sci Eng. 2017 Apr 10; 3(4):496-501. Molino NM, Neek M, Tucker JA, Nelson EL, Wang SW. PMID: 28989957; PMCID: PMC5630166.
      View in: PubMed   Mentions: 21     Fields:    
    19. Multicolor Immunofluorescent Imaging of Complex Cellular Mixtures on Micropallet Arrays Enables the Identification of Single Cells of Defined Phenotype. Adv Healthc Mater. 2016 Apr 06; 5(7):767-71. Westerhof TM, Li GP, Bachman M, Nelson EL. PMID: 26924570; PMCID: PMC5629097.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    20. Health Behaviors in Cervical Cancer Survivors and Associations with Quality of Life. Clin Ther. 2016 Mar; 38(3):467-75. Iyer NS, Osann K, Hsieh S, Tucker JA, Monk BJ, Nelson EL, Wenzel L. PMID: 26926320; PMCID: PMC4799758.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    21. Viral-mimicking protein nanoparticle vaccine for eliciting anti-tumor responses. Biomaterials. 2016 Apr; 86:83-91. Molino NM, Neek M, Tucker JA, Nelson EL, Wang SW. PMID: 26894870; PMCID: PMC4775383.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    22. Large area magnetic micropallet arrays for cell colony sorting. Lab Chip. 2016 Jan 07; 16(1):172-81. Cox-Muranami WA, Nelson EL, Li GP, Bachman M. PMID: 26606460; PMCID: PMC6201277.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    23. Psychosocial telephone counseling for survivors of cervical cancer: results of a randomized biobehavioral trial. J Clin Oncol. 2015 Apr 01; 33(10):1171-9. Wenzel L, Osann K, Hsieh S, Tucker JA, Monk BJ, Nelson EL. PMID: 25713429; PMCID: PMC4372853.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    24. Targeting TLR-4 with a novel pharmaceutical grade plant derived agonist, Immunomax®, as a therapeutic strategy for metastatic breast cancer. J Transl Med. 2014 Nov 29; 12:322. Ghochikyan A, Pichugin A, Bagaev A, Davtyan A, Hovakimyan A, Tukhvatulin A, Davtyan H, Shcheblyakov D, Logunov D, Chulkina M, Savilova A, Trofimov D, Nelson EL, Agadjanyan MG, Ataullakhanov RI. PMID: 25432242; PMCID: PMC4261251.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    25. Factors associated with poor quality of life among cervical cancer survivors: implications for clinical care and clinical trials. Gynecol Oncol. 2014 Nov; 135(2):266-72. Osann K, Hsieh S, Nelson EL, Monk BJ, Chase D, Cella D, Wenzel L. PMID: 25192629; PMCID: PMC4479396.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    26. Microfluidic dielectrophoretic sorter using gel vertical electrodes. Biomicrofluidics. 2014 May; 8(3):034105. Luo J, Nelson EL, Li GP, Bachman M. PMID: 24926390; PMCID: PMC4032422.
      View in: PubMed   Mentions: 2  
    27. Biomimetic protein nanoparticles facilitate enhanced dendritic cell activation and cross-presentation. ACS Nano. 2013 Nov 26; 7(11):9743-52. Molino NM, Anderson AK, Nelson EL, Wang SW. PMID: 24090491; PMCID: PMC3893022.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    28. Primary 4T1 tumor resection provides critical "window of opportunity" for immunotherapy. Clin Exp Metastasis. 2014 Feb; 31(2):185-98. Ghochikyan A, Davtyan A, Hovakimyan A, Davtyan H, Poghosyan A, Bagaev A, Ataullakhanov RI, Nelson EL, Agadjanyan MG. PMID: 24096737; PMCID: PMC3946940.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    29. Correction: Granulocyte-macrophage stimulating factor (GM-CSF) increases circulating dendritic cells but does not abrogate suppression of adaptive cellular immunity in patients with metastatic colorectal cancer receiving chemotherapy. Cancer Cell Int. 2013 Aug 15; 13(1):80. Martinez M, Ono N, Planutiene M, Planutis K, Nelson EL, Holcombe RF. PMID: 23945146; PMCID: PMC3751084.
      View in: PubMed   Mentions: 1  
    30. Biopsychological stress factors in BRCA mutation carriers. Psychosomatics. 2012 Nov-Dec; 53(6):582-90. Wenzel L, Osann K, Lester J, Kurz R, Hsieh S, Nelson EL, Karlan B. PMID: 23157996; PMCID: PMC4572843.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    31. Longitudinal change in telomere length and the chronic stress response in a randomized pilot biobehavioral clinical study: implications for cancer prevention. Cancer Prev Res (Phila). 2012 Oct; 5(10):1173-82. Biegler KA, Anderson AK, Wenzel LB, Osann K, Nelson EL. PMID: 22827974; PMCID: PMC4479406.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    32. Granulocyte-macrophage stimulating factor (GM-CSF) increases circulating dendritic cells but does not abrogate suppression of adaptive cellular immunity in patients with metastatic colorectal cancer receiving chemotherapy. Cancer Cell Int. 2012 01 23; 12(1):2. Martinez M, Ono N, Planutiene M, Planutis K, Nelson EL, Holcombe RF. PMID: 22270330; PMCID: PMC3283445.
      View in: PubMed   Mentions: 8  
    33. Cancer-testis antigen, BORIS based vaccine delivered by dendritic cells is extremely effective against a very aggressive and highly metastatic mouse mammary carcinoma. Cell Immunol. 2011; 270(2):188-97. Mkrtichyan M, Ghochikyan A, Davtyan H, Movsesyan N, Loukinov D, Lobanenkov V, Cribbs DH, Laust AK, Nelson EL, Agadjanyan MG. PMID: 21641588; PMCID: PMC3156877.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCellsPHPublic Health
    34. B-1 cell lymphoma in mice lacking the steroid and xenobiotic receptor, SXR. Mol Endocrinol. 2011 Jun; 25(6):933-43. Casey SC, Nelson EL, Turco GM, Janes MR, Fruman DA, Blumberg B. PMID: 21436254; PMCID: PMC3100607.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    35. Recruitment and retention results for a population-based cervical cancer biobehavioral clinical trial. Gynecol Oncol. 2011 Jun 01; 121(3):558-64. Osann K, Wenzel L, Dogan A, Hsieh S, Chase DM, Sappington S, Monk BJ, Nelson EL. PMID: 21402400; PMCID: PMC4572839.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    36. Longitudinal modulation of immune system cytokine profile during pregnancy. Cytokine. 2011 Feb; 53(2):170-7. Denney JM, Nelson EL, Wadhwa PD, Waters TP, Mathew L, Chung EK, Goldenberg RL, Culhane JF. PMID: 21123081; PMCID: PMC4610033.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCells
    37. Fabrication and biological evaluation of uniform extracellular matrix coatings on discontinuous photolithography generated micropallet arrays. J Biomed Mater Res A. 2010 Nov; 95(2):401-12. Gunn NM, Bachman M, Li GP, Nelson EL. PMID: 20648537; PMCID: PMC2981065.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    38. Ferromagnetic micropallets for magnetic capture of single adherent cells. Langmuir. 2010 Nov 16; 26(22):17703-11. Gunn NM, Chang R, Westerhof T, Li GP, Bachman M, Nelson EL. PMID: 20968293; PMCID: PMC2981060.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    39. C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells. J Immunol. 2009 Nov 15; 183(10):6175-85. Fraser DA, Laust AK, Nelson EL, Tenner AJ. PMID: 19864605; PMCID: PMC2843563.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    40. A human dendritic cell subset receptive to the Venezuelan equine encephalitis virus-derived replicon particle constitutively expresses IL-32. J Immunol. 2008 Sep 15; 181(6):4010-8. Nishimoto KP, Laust AK, Nelson EL. PMID: 18768856; PMCID: PMC5629096.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    41. Influence of prenatal psychosocial stress on cytokine production in adult women. Dev Psychobiol. 2008 Sep; 50(6):579-87. Entringer S, Kumsta R, Nelson EL, Hellhammer DH, Wadhwa PD, Wüst S. PMID: 18683180; PMCID: PMC2838479.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    42. Immunophototherapy using PDT combined with rapid intratumoral dendritic cell injection. Photochem Photobiol. 2008 Sep-Oct; 84(5):1257-64. Sur BW, Nguyen P, Sun CH, Tromberg BJ, Nelson EL. PMID: 18435703; PMCID: PMC3940280.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    43. Stress, immunity, and cervical cancer: biobehavioral outcomes of a randomized clinical trial [corrected]. Clin Cancer Res. 2008 Apr 01; 14(7):2111-8. Nelson EL, Wenzel LB, Osann K, Dogan-Ates A, Chantana N, Reina-Patton A, Laust AK, Nishimoto KP, Chicz-DeMet A, du Pont N, Monk BJ. PMID: 18381952; PMCID: PMC4572837.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    44. Concomitant sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease) and diffuse large B-cell lymphoma: a case report. J Med Case Rep. 2008 Mar 05; 2:70. Moore JC, Zhao X, Nelson EL. PMID: 18321383; PMCID: PMC2270859.
      View in: PubMed   Mentions: 8     Fields:    
    45. Fluorescence activated cell sorting (FACS) using RNAlater to minimize RNA degradation and perturbation of mRNA expression from cells involved in initial host microbe interactions. J Microbiol Methods. 2007 Jul; 70(1):205-8. Nishimoto KP, Newkirk D, Hou S, Fruehauf J, Nelson EL. PMID: 17512621.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    46. VRP immunotherapy targeting neu: treatment efficacy and evidence for immunoediting in a stringent rat mammary tumor model. Breast Cancer Res Treat. 2007 Dec; 106(3):371-82. Laust AK, Sur BW, Wang K, Hubby B, Smith JF, Nelson EL. PMID: 17351745.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCellsPHPublic Health
    47. Restricted and selective tropism of a Venezuelan equine encephalitis virus-derived replicon vector for human dendritic cells. Viral Immunol. 2007; 20(1):88-104. Nishimoto KP, Laust AK, Wang K, Kamrud KI, Hubby B, Smith JF, Nelson EL. PMID: 17425424.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    48. Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation. J Clin Invest. 2006 Aug; 116(8):2280-2289. Zhou C, Tabb MM, Nelson EL, Grün F, Verma S, Sadatrafiei A, Lin M, Mallick S, Forman BM, Thummel KE, Blumberg B. PMID: 16841097; PMCID: PMC1501109.
      View in: PubMed   Mentions: 169     Fields:    Translation:HumansCells
    49. An alternative flow cytometry strategy for peripheral blood dendritic cell enumeration in the setting of repetitive GM-CSF dosing. J Transl Med. 2006 Apr 24; 4:18. Wang K, Nishimoto KP, Mehta RS, Nelson EL. PMID: 16635268; PMCID: PMC1463012.
      View in: PubMed   Mentions: 4     Fields:    
    50. Validation and comparison of luminex multiplex cytokine analysis kits with ELISA: determinations of a panel of nine cytokines in clinical sample culture supernatants. J Reprod Immunol. 2005 Aug; 66(2):175-91. dupont NC, Wang K, Wadhwa PD, Culhane JF, Nelson EL. PMID: 16029895; PMCID: PMC5738327.
      View in: PubMed   Mentions: 127     Fields:    Translation:Humans
    51. Venezuelan equine encephalitis replicon immunization overcomes intrinsic tolerance and elicits effective anti-tumor immunity to the 'self' tumor-associated antigen, neu in a rat mammary tumor model. Breast Cancer Res Treat. 2003 Dec; 82(3):169-83. Nelson EL, Prieto D, Alexander TG, Pushko P, Lofts LA, Rayner JO, Kamrud KI, Fralish B, Smith JF. PMID: 14703064.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCellsPHPublic Health
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