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Enrico Gratton

Title(s)Professor, Biomedical Engineering
Phone(949) 824-2674
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    Collapse Research 
    Collapse Research Activities and Funding
    Imaging of Brain Function Using Near-Infrared Methods
    NIH/NIBIB R01EB000559Sep 1, 2002 - Jul 31, 2006
    Role: Principal Investigator
    Laboratory for Fluorescence Dynamics
    NIH/NIGMS P41GM103540Aug 1, 1997 - Jun 30, 2021
    Role: Principal Investigator
    Vascular Insufficiency in Brain Circulation
    NIH/NICHD R01HD041342Sep 1, 1995 - Aug 31, 2005
    Role: Principal Investigator
    VASCULAR INSUFFICIENCY IN PERIPHERAL TISSUE
    NIH/NCRR R01RR010966Sep 1, 1995 - Aug 31, 2001
    Role: Principal Investigator
    CATALYTIC ANTIBODIES--CHARGE TRANSFER REACTIONS
    NIH/FIC R03TW000427Mar 1, 1994 - Feb 28, 1998
    Role: Principal Investigator
    OPTICAL IMAGING OF THICK TISSUES
    NIH/NCI R01CA057032Apr 1, 1992 - Nov 30, 2001
    Role: Principal Investigator
    Laboratory for Fluorescence Dynamics
    NIH/NCRR P41RR003155Aug 1, 1986 - Jun 30, 2016
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Ranjit S, Datta R, Dvornikov AS, Gratton E. Multicomponent Analysis of Phasor Plot in a Single Pixel to Calculate Changes of Metabolic Trajectory in Biological Systems. J Phys Chem A. 2019 Oct 22. PMID: 31638388.
      View in: PubMed
    2. Trivedi P, Palomba F, Niedzialkowska E, Digman MA, Gratton E, Stukenberg PT. The inner centromere is a biomolecular condensate scaffolded by the chromosomal passenger complex. Nat Cell Biol. 2019 Sep; 21(9):1127-1137. PMID: 31481798.
      View in: PubMed
    3. Levi M, Gratton E, Forster IC, Hernando N, Wagner CA, Biber J, Sorribas V, Murer H. Mechanisms of phosphate transport. Nat Rev Nephrol. 2019 Aug; 15(8):482-500. PMID: 31168066.
      View in: PubMed
    4. Gabriel M, Anzalone A, Gratton E, Estrada LC. A tracking-based nanoimaging method for fast detection of surfaces' inhomogeneities using gold nanoparticles. Microsc Res Tech. 2019 Nov; 82(11):1835-1842. PMID: 31318476.
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    5. Dvornikov A, Malacrida L, Gratton E. The DIVER Microscope for Imaging in Scattering Media. Methods Protoc. 2019 Jun 21; 2(2). PMID: 31234383.
      View in: PubMed
    6. Ranjit S, Malacrida L, Stakic M, Gratton E. Determination of the metabolic index using the fluorescence lifetime of free and bound nicotinamide adenine dinucleotide using the phasor approach. J Biophotonics. 2019 Jun 13; e201900156. PMID: 31194290.
      View in: PubMed
    7. Rodriguez-Agudo D, Malacrida L, Kakiyama G, Sparrer T, Fortes C, Maceyka M, Subler MA, Windle JJ, Gratton E, Pandak WM, Gil G. StarD5: an ER stress protein regulates plasma membrane and intracellular cholesterol homeostasis. J Lipid Res. 2019 Jun; 60(6):1087-1098. PMID: 31015253.
      View in: PubMed
    8. Polyzos AA, Lee DY, Datta R, Hauser M, Budworth H, Holt A, Mihalik S, Goldschmidt P, Frankel K, Trego K, Bennett MJ, Vockley J, Xu K, Gratton E, McMurray CT. Metabolic Reprogramming in Astrocytes Distinguishes Region-Specific Neuronal Susceptibility in Huntington Mice. Cell Metab. 2019 Jun 04; 29(6):1258-1273.e11. PMID: 30930170.
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    9. Lou J, Scipioni L, Wright BK, Bartolec TK, Zhang J, Masamsetti VP, Gaus K, Gratton E, Cesare AJ, Hinde E. Phasor histone FLIM-FRET microscopy quantifies spatiotemporal rearrangement of chromatin architecture during the DNA damage response. Proc Natl Acad Sci U S A. 2019 04 09; 116(15):7323-7332. PMID: 30918123.
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    10. Ou CY, Vu T, Grunwald JT, Toledano M, Zimak J, Toosky M, Shen B, Zell JA, Gratton E, Abram TJ, Zhao W. An ultrasensitive test for profiling circulating tumor DNA using integrated comprehensive droplet digital detection. Lab Chip. 2019 03 13; 19(6):993-1005. PMID: 30735225.
      View in: PubMed
    11. Planes N, Digman MA, Vanderheyden PPML, Gratton E, Caballero-George C. Number and brightness analysis to study spatio-temporal distribution of the angiotensin II AT1 and the endothelin-1 ETA receptors: Influence of ligand binding. Biochim Biophys Acta Gen Subj. 2019 May; 1863(5):917-924. PMID: 30851407.
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    12. Chen H, Ma N, Kagawa K, Kawahito S, Digman M, Gratton E. Widefield multifrequency fluorescence lifetime imaging using a two-tap complementary metal-oxide semiconductor camera with lateral electric field charge modulators. J Biophotonics. 2019 May; 12(5):e201800223. PMID: 30421535.
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    13. Hedde PN, Abram T, Vu T, Zhao W, Gratton E. Fluorescence lifetime detection with particle counting devices. Biomed Opt Express. 2019 Mar 01; 10(3):1223-1233. PMID: 30891341.
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    14. Begarani F, D'Autilia F, Signore G, Del Grosso A, Cecchini M, Gratton E, Beltram F, Cardarelli F. Capturing Metabolism-Dependent Solvent Dynamics in the Lumen of a Trafficking Lysosome. ACS Nano. 2019 Feb 26; 13(2):1670-1682. PMID: 30649861.
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    15. Levi M, Gratton E. Visualizing the regulation of SLC34 proteins at the apical membrane. Pflugers Arch. 2019 Apr; 471(4):533-542. PMID: 30613865.
      View in: PubMed
    16. Scipioni L, Lanzanó L, Diaspro A, Gratton E. Comprehensive correlation analysis for super-resolution dynamic fingerprinting of cellular compartments using the Zeiss Airyscan detector. Nat Commun. 2018 11 30; 9(1):5120. PMID: 30504919.
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    17. Hellenkamp B, Schmid S, Doroshenko O, Opanasyuk O, Kühnemuth R, Adariani SR, Ambrose B, Aznauryan M, Barth A, Birkedal V, Bowen ME, Chen H, Cordes T, Eilert T, Fijen C, Gebhardt C, Götz M, Gouridis G, Gratton E, Ha T, Hao P, Hanke CA, Hartmann A, Hendrix J, Hildebrandt LL, Hirschfeld V, Hohlbein J, Hua B, Hübner CG, Kallis E, Kapanidis AN, Kim JY, Krainer G, Lamb DC, Lee NK, Lemke EA, Levesque B, Levitus M, McCann JJ, Naredi-Rainer N, Nettels D, Ngo T, Qiu R, Robb NC, Röcker C, Sanabria H, Schlierf M, Schröder T, Schuler B, Seidel H, Streit L, Thurn J, Tinnefeld P, Tyagi S, Vandenberk N, Vera AM, Weninger KR, Wünsch B, Yanez-Orozco IS, Michaelis J, Seidel CAM, Craggs TD, Hugel T. Publisher Correction: Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study. Nat Methods. 2018 Nov; 15(11):984. PMID: 30327572.
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    18. Ranjit S, Malacrida L, Gratton E. Differences between FLIM phasor analyses for data collected with the Becker and Hickl SPC830 card and with the FLIMbox card. Microsc Res Tech. 2018 Sep; 81(9):980-989. PMID: 30295346.
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    19. Ranjit S, Malacrida L, Jameson DM, Gratton E. Fit-free analysis of fluorescence lifetime imaging data using the phasor approach. Nat Protoc. 2018 09; 13(9):1979-2004. PMID: 30190551.
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    20. Hellenkamp B, Schmid S, Doroshenko O, Opanasyuk O, Kühnemuth R, Rezaei Adariani S, Ambrose B, Aznauryan M, Barth A, Birkedal V, Bowen ME, Chen H, Cordes T, Eilert T, Fijen C, Gebhardt C, Götz M, Gouridis G, Gratton E, Ha T, Hao P, Hanke CA, Hartmann A, Hendrix J, Hildebrandt LL, Hirschfeld V, Hohlbein J, Hua B, Hübner CG, Kallis E, Kapanidis AN, Kim JY, Krainer G, Lamb DC, Lee NK, Lemke EA, Levesque B, Levitus M, McCann JJ, Naredi-Rainer N, Nettels D, Ngo T, Qiu R, Robb NC, Röcker C, Sanabria H, Schlierf M, Schröder T, Schuler B, Seidel H, Streit L, Thurn J, Tinnefeld P, Tyagi S, Vandenberk N, Vera AM, Weninger KR, Wünsch B, Yanez-Orozco IS, Michaelis J, Seidel CAM, Craggs TD, Hugel T. Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study. Nat Methods. 2018 09; 15(9):669-676. PMID: 30171252.
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    21. Dvornikov A, Gratton E. Hyperspectral imaging in highly scattering media by the spectral phasor approach using two filters. Biomed Opt Express. 2018 Aug 01; 9(8):3503-3511. PMID: 30338135.
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    22. Malacrida L, Gratton E. LAURDAN fluorescence and phasor plots reveal the effects of a H2O2 bolus in NIH-3T3 fibroblast membranes dynamics and hydration. Free Radic Biol Med. 2018 11 20; 128:144-156. PMID: 29885356.
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    23. Pedrote MM, de Oliveira GAP, Felix AL, Mota MF, Marques MA, Soares IN, Iqbal A, Norberto DR, Gomes AMO, Gratton E, Cino EA, Silva JL. Aggregation-primed molten globule conformers of the p53 core domain provide potential tools for studying p53C aggregation in cancer. J Biol Chem. 2018 07 20; 293(29):11374-11387. PMID: 29853637.
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    24. Malacrida L, Rao E, Gratton E. Comparison between iMSD and 2D-pCF analysis for molecular motion studies on in vivo cells: The case of the epidermal growth factor receptor. Methods. 2018 05 01; 140-141:74-84. PMID: 29501424.
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    25. Staaf E, Hedde PN, Bagawath Singh S, Piguet J, Gratton E, Johansson S. Educated natural killer cells show dynamic movement of the activating receptor NKp46 and confinement of the inhibitory receptor Ly49A. Sci Signal. 2018 02 13; 11(517). PMID: 29440510.
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    26. Mäntylä E, Chacko JV, Aho V, Parrish CR, Shahin V, Kann M, Digman MA, Gratton E, Vihinen-Ranta M. Viral highway to nucleus exposed by image correlation analyses. Sci Rep. 2018 01 18; 8(1):1152. PMID: 29348472.
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    27. Gach JS, Bouzin M, Wong MP, Chromikova V, Gorlani A, Yu KT, Sharma B, Gratton E, Forthal DN. Human immunodeficiency virus type-1 (HIV-1) evades antibody-dependent phagocytosis. PLoS Pathog. 2017 12; 13(12):e1006793. PMID: 29281723.
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    28. Malacrida L, Hedde PN, Ranjit S, Cardarelli F, Gratton E. Visualization of barriers and obstacles to molecular diffusion in live cells by spatial pair-cross-correlation in two dimensions. Biomed Opt Express. 2018 01 01; 9(1):303-321. PMID: 29359105.
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    29. Davey RJ, Digman MA, Gratton E, Moens PDJ. Quantitative image mean squared displacement (iMSD) analysis of the dynamics of profilin 1 at the membrane of live cells. Methods. 2018 05 01; 140-141:119-125. PMID: 29242135.
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    30. Digiacomo L, Cardarelli F, Pozzi D, Palchetti S, Digman MA, Gratton E, Capriotti AL, Mahmoudi M, Caracciolo G. An apolipoprotein-enriched biomolecular corona switches the cellular uptake mechanism and trafficking pathway of lipid nanoparticles. Nanoscale. 2017 Nov 16; 9(44):17254-17262. PMID: 29115333.
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    31. Wang XX, Wang D, Luo Y, Myakala K, Dobrinskikh E, Rosenberg AZ, Levi J, Kopp JB, Field A, Hill A, Lucia S, Qiu L, Jiang T, Peng Y, Orlicky D, Garcia G, Herman-Edelstein M, D'Agati V, Henriksen K, Adorini L, Pruzanski M, Xie C, Krausz KW, Gonzalez FJ, Ranjit S, Dvornikov A, Gratton E, Levi M. FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity. J Am Soc Nephrol. 2018 01; 29(1):118-137. PMID: 29089371.
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    32. Bohórquez-Hernández A, Gratton E, Pacheco J, Asanov A, Vaca L. Cholesterol modulates the cellular localization of Orai1 channels and its disposition among membrane domains. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Dec; 1862(12):1481-1490. PMID: 28919480.
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    33. Malacrida L, Jameson DM, Gratton E. A multidimensional phasor approach reveals LAURDAN photophysics in NIH-3T3 cell membranes. Sci Rep. 2017 08 23; 7(1):9215. PMID: 28835608.
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    34. Hedde PN, Malacrida L, Ahrar S, Siryaporn A, Gratton E. sideSPIM - selective plane illumination based on a conventional inverted microscope. Biomed Opt Express. 2017 Sep 01; 8(9):3918-3937. PMID: 29026679.
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    35. Stortz M, Presman DM, Bruno L, Annibale P, Dansey MV, Burton G, Gratton E, Pecci A, Levi V. Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape. Sci Rep. 2017 07 24; 7(1):6219. PMID: 28740156.
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    36. Ranjit S, Dvornikov A, Dobrinskikh E, Wang X, Luo Y, Levi M, Gratton E. Erratum: Measuring the effect of Western diet on liver tissue architecture by FLIM autofluorescence and harmonic generation microscopy: erratum. Biomed Opt Express. 2017 07 01; 8(7):3501. PMID: 28717585.
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    37. Bhattacharjee A, Datta R, Gratton E, Hochbaum AI. Metabolic fingerprinting of bacteria by fluorescence lifetime imaging microscopy. Sci Rep. 2017 06 16; 7(1):3743. PMID: 28623341.
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    38. Ranjit S, Dvornikov A, Dobrinskikh E, Wang X, Luo Y, Levi M, Gratton E. Measuring the effect of a Western diet on liver tissue architecture by FLIM autofluorescence and harmonic generation microscopy. Biomed Opt Express. 2017 Jul 01; 8(7):3143-3154. PMID: 28717559.
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    39. Herrington KA, Trinh AL, Dang C, O'Shaughnessy E, Hahn KM, Gratton E, Digman MA, Sütterlin C. Spatial analysis of Cdc42 activity reveals a role for plasma membrane-associated Cdc42 in centrosome regulation. Mol Biol Cell. 2017 Jul 15; 28(15):2135-2145. PMID: 28539409.
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    40. Ceccarelli A, Di Venere A, Nicolai E, De Luca A, Rosato N, Gratton E, Mei G, Caccuri AM. New insight into the interaction of TRAF2 C-terminal domain with lipid raft microdomains. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Sep; 1862(9):813-822. PMID: 28499815.
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    41. Porcaro F, Miao Y, Kota R, Haun JB, Polzonetti G, Battocchio C, Gratton E. Fluctuation Spectroscopy Analysis of Glucose Capped Gold Nanoparticles. Langmuir. 2016 12 20; 32(50):13409-13417. PMID: 27935716.
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    42. Aguilar-Arnal L, Ranjit S, Stringari C, Orozco-Solis R, Gratton E, Sassone-Corsi P. Spatial dynamics of SIRT1 and the subnuclear distribution of NADH species. Proc Natl Acad Sci U S A. 2016 Nov 08; 113(45):12715-12720. PMID: 27791113.
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    43. Cinco R, Digman MA, Gratton E, Luderer U. Spatial Characterization of Bioenergetics and Metabolism of Primordial to Preovulatory Follicles in Whole Ex Vivo Murine Ovary. Biol Reprod. 2016 12; 95(6):129. PMID: 27683265.
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    44. Chen H, Gratton E, Digman MA. Self-assisted optothermal trapping of gold nanorods under two-photon excitation. Methods Appl Fluoresc. 2016 09 06; 4(3):035003. PMID: 28355163.
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    45. Dvornikov A, Gratton E. Imaging in turbid media: a transmission detector gives 2-3 order of magnitude enhanced sensitivity compared to epi-detection schemes. Biomed Opt Express. 2016 Sep 01; 7(9):3747-3755. PMID: 27699135.
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    46. Di Rienzo C, Gratton E, Beltram F, Cardarelli F. Spatiotemporal Fluctuation Analysis: A Powerful Tool for the Future Nanoscopy of Molecular Processes. Biophys J. 2016 Aug 23; 111(4):679-685. PMID: 27558712.
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    47. Sobrino A, Phan DT, Datta R, Wang X, Hachey SJ, Romero-López M, Gratton E, Lee AP, George SC, Hughes CC. 3D microtumors in vitro supported by perfused vascular networks. Sci Rep. 2016 08 23; 6:31589. PMID: 27549930.
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    48. Di Rienzo C, Cardarelli F, Di Luca M, Beltram F, Gratton E. Diffusion Tensor Analysis by Two-Dimensional Pair Correlation of Fluorescence Fluctuations in Cells. Biophys J. 2016 Aug 23; 111(4):841-851. PMID: 27558727.
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    49. Ranjit S, Dobrinskikh E, Montford J, Dvornikov A, Lehman A, Orlicky DJ, Nemenoff R, Gratton E, Levi M, Furgeson S. Label-free fluorescence lifetime and second harmonic generation imaging microscopy improves quantification of experimental renal fibrosis. Kidney Int. 2016 11; 90(5):1123-1128. PMID: 27555119.
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    50. Ranjit S, Dvornikov A, Levi M, Furgeson S, Gratton E. Characterizing fibrosis in UUO mice model using multiparametric analysis of phasor distribution from FLIM images. Biomed Opt Express. 2016 Sep 01; 7(9):3519-3530. PMID: 27699117.
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    51. Scipioni L, Gratton E, Diaspro A, Lanzanò L. Phasor Analysis of Local ICS Detects Heterogeneity in Size and Number of Intracellular Vesicles. Biophys J. 2016 Aug 09; 111(3):619-629. PMID: 27508445.
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    52. Serebryannyy LA, Parilla M, Annibale P, Cruz CM, Laster K, Gratton E, Kudryashov D, Kosak ST, Gottardi CJ, de Lanerolle P. Persistent nuclear actin filaments inhibit transcription by RNA polymerase II. J Cell Sci. 2016 09 15; 129(18):3412-25. PMID: 27505898.
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    53. Malacrida L, Astrada S, Briva A, Bollati-Fogolín M, Gratton E, Bagatolli LA. Spectral phasor analysis of LAURDAN fluorescence in live A549 lung cells to study the hydration and time evolution of intracellular lamellar body-like structures. Biochim Biophys Acta. 2016 11; 1858(11):2625-2635. PMID: 27480804.
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    54. Digiacomo L, Digman MA, Gratton E, Caracciolo G. Development of an image Mean Square Displacement (iMSD)-based method as a novel approach to study the intracellular trafficking of nanoparticles. Acta Biomater. 2016 09 15; 42:189-198. PMID: 27449340.
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    55. Noutsi P, Gratton E, Chaieb S. Assessment of Membrane Fluidity Fluctuations during Cellular Development Reveals Time and Cell Type Specificity. PLoS One. 2016; 11(6):e0158313. PMID: 27362860.
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    56. Hedde PN, Gratton E. Selective plane illumination microscopy with a light sheet of uniform thickness formed by an electrically tunable lens. Microsc Res Tech. 2018 Sep; 81(9):924-928. PMID: 27338568.
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    57. Lin S, Hedde PN, Venugopalan V, Gratton E, Khine M. Multi-scale silica structures for improved HIV-1 Capsid (p24) antigen detection. Analyst. 2016 Jun 20; 141(13):4181-8. PMID: 27163263.
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    58. Clark NM, Hinde E, Winter CM, Fisher AP, Crosti G, Blilou I, Gratton E, Benfey PN, Sozzani R. Tracking transcription factor mobility and interaction in Arabidopsis roots with fluorescence correlation spectroscopy. Elife. 2016 06 11; 5. PMID: 27288545.
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    59. Ma N, Digman MA, Malacrida L, Gratton E. Measurements of absolute concentrations of NADH in cells using the phasor FLIM method. Biomed Opt Express. 2016 Jul 01; 7(7):2441-52. PMID: 27446681.
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    60. Szymanska AF, Heylman C, Datta R, Gratton E, Nenadic Z. Automated detection and analysis of depolarization events in human cardiomyocytes using MaDEC. Comput Biol Med. 2016 08 01; 75:109-17. PMID: 27281718.
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    61. Cardarelli F, Digiacomo L, Marchini C, Amici A, Salomone F, Fiume G, Rossetta A, Gratton E, Pozzi D, Caracciolo G. The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implication for gene delivery. Sci Rep. 2016 05 11; 6:25879. PMID: 27165510.
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    62. Borrego SL, Fahrmann J, Datta R, Stringari C, Grapov D, Zeller M, Chen Y, Wang P, Baldi P, Gratton E, Fiehn O, Kaiser P. Metabolic changes associated with methionine stress sensitivity in MDA-MB-468 breast cancer cells. Cancer Metab. 2016; 4:9. PMID: 27141305.
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    63. Alfonso-García A, Smith TD, Datta R, Luu TU, Gratton E, Potma EO, Liu WF. Label-free identification of macrophage phenotype by fluorescence lifetime imaging microscopy. J Biomed Opt. 2016 Apr 30; 21(4):46005. PMID: 27086689.
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    64. Sosnik J, Zheng L, Rackauckas CV, Digman M, Gratton E, Nie Q, Schilling TF. Noise modulation in retinoic acid signaling sharpens segmental boundaries of gene expression in the embryonic zebrafish hindbrain. Elife. 2016 Apr 12; 5:e14034. PMID: 27067377.
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    65. Datta R, Heylman C, George SC, Gratton E. Label-free imaging of metabolism and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes. Biomed Opt Express. 2016 May 01; 7(5):1690-701. PMID: 27231614.
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    66. Hinde E, Pandžic E, Yang Z, Ng IH, Jans DA, Bogoyevitch MA, Gratton E, Gaus K. Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness. Nat Commun. 2016 Mar 24; 7:11047. PMID: 27009358.
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    67. Brenner MD, Zhou R, Conway DE, Lanzano L, Gratton E, Schwartz MA, Ha T. Spider Silk Peptide Is a Compact, Linear Nanospring Ideal for Intracellular Tension Sensing. Nano Lett. 2016 Mar 09; 16(3):2096-102. PMID: 26824190.
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    68. Wang B, Rong X, Duerr MA, Hermanson DJ, Hedde PN, Wong JS, Vallim TQ, Cravatt BF, Gratton E, Ford DA, Tontonoz P. Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet. Cell Metab. 2016 Mar 08; 23(3):492-504. PMID: 26833026.
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    69. Annibale P, Dvornikov A, Gratton E. Optical measurement of focal offset in tunable lenses. Opt Express. 2016 Jan 25; 24(2):1031-6. PMID: 26832485.
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    70. Heylman C, Datta R, Sobrino A, George S, Gratton E. Supervised Machine Learning for Classification of the Electrophysiological Effects of Chronotropic Drugs on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. PLoS One. 2015; 10(12):e0144572. PMID: 26695765.
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    71. Lakhani VV, Hinde E, Gratton E, Elston TC. Spatio-Temporal Regulation of Rac1 Mobility by Actin Islands. PLoS One. 2015; 10(11):e0143753. PMID: 26606145.
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    72. Malacrida L, Gratton E, Jameson DM. Model-free methods to study membrane environmental probes: a comparison of the spectral phasor and generalized polarization approaches. Methods Appl Fluoresc. 2015 Nov 12; 3(4):047001. PMID: 29148515.
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    73. Malacrida L, Gratton E, Jameson DM. Model-free methods to study membrane environmental probes: a comparison of the spectral phasor and generalized polarization approaches. Methods Appl Fluoresc. 2015 Dec; 3(4). PMID: 27182438.
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    74. Moore JS, Xantheas SS, Grate JW, Wietsma TW, Gratton E, Vasdekis AE. Modular Polymer Biosensors by Solvent Immersion Imprint Lithography. J Polym Sci B Polym Phys. 2016 Jan 01; 54(1):98-103. PMID: 27867256.
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    75. Chen H, Holst G, Gratton E. Modulated CMOS camera for fluorescence lifetime microscopy. Microsc Res Tech. 2015 Dec; 78(12):1075-81. PMID: 26500051.
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    76. Zhang K, Kang DK, Ali MM, Liu L, Labanieh L, Lu M, Riazifar H, Nguyen TN, Zell JA, Digman MA, Gratton E, Li J, Zhao W. Digital quantification of miRNA directly in plasma using integrated comprehensive droplet digital detection. Lab Chip. 2015 Nov 07; 15(21):4217-26. PMID: 26387763.
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    77. Mieruszynski S, Digman MA, Gratton E, Jones MR. Characterization of exogenous DNA mobility in live cells through fluctuation correlation spectroscopy. Sci Rep. 2015 Sep 10; 5:13848. PMID: 26354725.
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    78. Hedde PN, Ranjit S, Gratton E. 3D fluorescence anisotropy imaging using selective plane illumination microscopy. Opt Express. 2015 Aug 24; 23(17):22308-17. PMID: 26368202.
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    79. Ranjit S, Dvornikov A, Stakic M, Hong SH, Levi M, Evans RM, Gratton E. Imaging Fibrosis and Separating Collagens using Second Harmonic Generation and Phasor Approach to Fluorescence Lifetime Imaging. Sci Rep. 2015 Aug 21; 5:13378. PMID: 26293987.
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    80. Hendrix J, Baumgärtel V, Schrimpf W, Ivanchenko S, Digman MA, Gratton E, Kräusslich HG, Müller B, Lamb DC. Live-cell observation of cytosolic HIV-1 assembly onset reveals RNA-interacting Gag oligomers. J Cell Biol. 2015 Aug 17; 210(4):629-46. PMID: 26283800.
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    81. Hinde E, Cardarelli F, Gratton E. Spatiotemporal regulation of Heterochromatin Protein 1-alpha oligomerization and dynamics in live cells. Sci Rep. 2015 Aug 04; 5:12001. PMID: 26238434.
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    82. Ito A, Hong C, Rong X, Zhu X, Tarling EJ, Hedde PN, Gratton E, Parks J, Tontonoz P. LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling. Elife. 2015 Jul 14; 4:e08009. PMID: 26173179.
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    83. Adu-Gyamfi E, Johnson KA, Fraser ME, Scott JL, Soni SP, Jones KR, Digman MA, Gratton E, Tessier CR, Stahelin RV. Host Cell Plasma Membrane Phosphatidylserine Regulates the Assembly and Budding of Ebola Virus. J Virol. 2015 Sep; 89(18):9440-53. PMID: 26136573.
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    84. Hedde PN, Gratton E. Active focus stabilization for upright selective plane illumination microscopy. Opt Express. 2015 Jun 01; 23(11):14707-14. PMID: 26072829.
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    85. Mieruszynski S, Briggs C, Digman MA, Gratton E, Jones MR. Live Cell Characterization of DNA Aggregation Delivered through Lipofection. Sci Rep. 2015 May 27; 5:10528. PMID: 26013547.
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    86. Annibale P, Dvornikov A, Gratton E. Electrically tunable lens speeds up 3D orbital tracking. Biomed Opt Express. 2015 Jun 01; 6(6):2181-90. PMID: 26114037.
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    87. Datta R, Alfonso-García A, Cinco R, Gratton E. Fluorescence lifetime imaging of endogenous biomarker of oxidative stress. Sci Rep. 2015 May 20; 5:9848. PMID: 25993434.
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    88. Anzalone A, Gabriel M, Estrada LC, Gratton E. Spectral properties of single gold nanoparticles in close proximity to biological fluorophores excited by 2-photon excitation. PLoS One. 2015; 10(4):e0124975. PMID: 25909648.
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    89. Sanchez SA, Gratton E, Zanocco AL, Lemp E, Gunther G. Correction: Sucrose monoester micelles size determined by fluorescence correlation spectroscopy (FCS). PLoS One. 2015; 10(4):e0125123. PMID: 25885966.
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    90. Olivera-Couto A, Salzman V, Mailhos M, Digman MA, Gratton E, Aguilar PS. Eisosomes are dynamic plasma membrane domains showing pil1-lsp1 heteroligomer binding equilibrium. Biophys J. 2015 Apr 07; 108(7):1633-1644. PMID: 25863055.
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    91. Lanzanò L, Coto Hernández I, Castello M, Gratton E, Diaspro A, Vicidomini G. Encoding and decoding spatio-temporal information for super-resolution microscopy. Nat Commun. 2015 Apr 02; 6:6701. PMID: 25833391.
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    92. Rong X, Wang B, Dunham MM, Hedde PN, Wong JS, Gratton E, Young SG, Ford DA, Tontonoz P. Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion. Elife. 2015 Mar 25; 4. PMID: 25806685.
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    93. Moens PDJ, Digman MA, Gratton E. Modes of diffusion of cholera toxin bound to GM1 on live cell membrane by image mean square displacement analysis. Biophys J. 2015 Mar 24; 108(6):1448-1458. PMID: 25809257.
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    94. Perumal V, Krishnan K, Gratton E, Dharmarajan AM, Fox SA. Number and brightness analysis of sFRP4 domains in live cells demonstrates vesicle association signal of the NLD domain and dynamic intracellular responses to Wnt3a. Int J Biochem Cell Biol. 2015 Jul; 64:91-6. PMID: 25805505.
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    95. Annibale P, Gratton E. Single cell visualization of transcription kinetics variance of highly mobile identical genes using 3D nanoimaging. Sci Rep. 2015 Mar 19; 5:9258. PMID: 25788248.
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    96. Plotegher N, Stringari C, Jahid S, Veronesi M, Girotto S, Gratton E, Bubacco L. NADH fluorescence lifetime is an endogenous reporter of a-synuclein aggregation in live cells. FASEB J. 2015 Jun; 29(6):2484-94. PMID: 25713058.
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    97. Chen H, Gratton E, Digman MA. Spectral properties and dynamics of gold nanorods revealed by EMCCD-based spectral phasor method. Microsc Res Tech. 2015 Apr; 78(4):283-93. PMID: 25684346.
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    98. Golfetto O, Hinde E, Gratton E. The Laurdan spectral phasor method to explore membrane micro-heterogeneity and lipid domains in live cells. Methods Mol Biol. 2015; 1232:273-90. PMID: 25331141.
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    99. Stringari C, Wang H, Geyfman M, Crosignani V, Kumar V, Takahashi JS, Andersen B, Gratton E. In vivo single-cell detection of metabolic oscillations in stem cells. Cell Rep. 2015 Jan 06; 10(1):1-7. PMID: 25543138.
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    100. Di Rienzo C, Piazza V, Gratton E, Beltram F, Cardarelli F. Probing short-range protein Brownian motion in the cytoplasm of living cells. Nat Commun. 2014 Dec 23; 5:5891. PMID: 25532887.
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    101. Ranjit S, Lanzano L, Gratton E. Mapping diffusion in a living cell via the phasor approach. Biophys J. 2014 Dec 16; 107(12):2775-2785. PMID: 25517145.
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    102. Ranjit S, Dvornikov A, Holland DA, Reinhart GD, Jameson DM, Gratton E. Application of three-photon excitation FCS to the study of protein oligomerization. J Phys Chem B. 2014 Dec 18; 118(50):14627-31. PMID: 25438088.
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    103. Hedde PN, Stakic M, Gratton E. Rapid measurement of molecular transport and interaction inside living cells using single plane illumination. Sci Rep. 2014 Nov 14; 4:7048. PMID: 25394360.
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    104. Kang DK, Ali MM, Zhang K, Huang SS, Peterson E, Digman MA, Gratton E, Zhao W. Rapid detection of single bacteria in unprocessed blood using Integrated Comprehensive Droplet Digital Detection. Nat Commun. 2014 Nov 13; 5:5427. PMID: 25391809.
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    105. Bonaventura G, Barcellona ML, Golfetto O, Nourse JL, Flanagan LA, Gratton E. Laurdan monitors different lipids content in eukaryotic membrane during embryonic neural development. Cell Biochem Biophys. 2014 Nov; 70(2):785-94. PMID: 24839062.
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    106. Adu-Gyamfi E, Soni SP, Jee CS, Digman MA, Gratton E, Stahelin RV. A loop region in the N-terminal domain of Ebola virus VP40 is important in viral assembly, budding, and egress. Viruses. 2014 Oct 17; 6(10):3837-54. PMID: 25330123.
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    107. Di Rienzo C, Gratton E, Beltram F, Cardarelli F. From fast fluorescence imaging to molecular diffusion law on live cell membranes in a commercial microscope. J Vis Exp. 2014 Oct 09; (92):e51994. PMID: 25350683.
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    108. Anzalone A, Annibale P, Gratton E. 3D orbital tracking in a modified two-photon microscope: an application to the tracking of intracellular vesicles. J Vis Exp. 2014 Oct 01; (92):e51794. PMID: 25350070.
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    109. Nicolai E, Garau S, Favalli C, D'Agostini C, Gratton E, Motolese G, Rosato N. Evaluation of BiesseBioscreen as a new methodology for bacteriuria screening. New Microbiol. 2014 Oct; 37(4):495-501. PMID: 25387286.
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    110. Bachir AI, Zareno J, Moissoglu K, Plow EF, Gratton E, Horwitz AR. Integrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesions. Curr Biol. 2014 Aug 18; 24(16):1845-53. PMID: 25088556.
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    111. Subashchandrabose SR, Krishnan K, Gratton E, Megharaj M, Naidu R. Potential of fluorescence imaging techniques to monitor mutagenic PAH uptake by microalga. Environ Sci Technol. 2014 Aug 19; 48(16):9152-60. PMID: 25020149.
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    112. Hinde E, Kong X, Yokomori K, Gratton E. Chromatin dynamics during DNA repair revealed by pair correlation analysis of molecular flow in the nucleus. Biophys J. 2014 Jul 01; 107(1):55-65. PMID: 24988341.
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    113. Chiu CL, Aguilar JS, Tsai CY, Wu G, Gratton E, Digman MA. Nanoimaging of focal adhesion dynamics in 3D. PLoS One. 2014; 9(6):e99896. PMID: 24959851.
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    114. Lanzanò L, Gratton E. Orbital Single Particle Tracking on a commercial confocal microscope using piezoelectric stage feedback. Methods Appl Fluoresc. 2014 Jun 01; 2(2). PMID: 25419461.
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    115. Pate KT, Stringari C, Sprowl-Tanio S, Wang K, TeSlaa T, Hoverter NP, McQuade MM, Garner C, Digman MA, Teitell MA, Edwards RA, Gratton E, Waterman ML. Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer. EMBO J. 2014 Jul 01; 33(13):1454-73. PMID: 24825347.
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    116. Paladino S, Lebreton S, Tivodar S, Formiggini F, Ossato G, Gratton E, Tramier M, Coppey-Moisan M, Zurzolo C. Golgi sorting regulates organization and activity of GPI proteins at apical membranes. Nat Chem Biol. 2014 May; 10(5):350-357. PMID: 24681536.
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    117. Crosignani V, Jahid S, Dvornikov AS, Gratton E. A deep tissue fluorescence imaging system with enhanced SHG detection capabilities. Microsc Res Tech. 2014 May; 77(5):368-73. PMID: 24610799.
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    118. Hinde E, Yokomori K, Gaus K, Hahn KM, Gratton E. Fluctuation-based imaging of nuclear Rac1 activation by protein oligomerisation. Sci Rep. 2014 Feb 27; 4:4219. PMID: 24573109.
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    119. Plotegher N, Gratton E, Bubacco L. Number and Brightness analysis of alpha-synuclein oligomerization and the associated mitochondrial morphology alterations in live cells. Biochim Biophys Acta. 2014 Jun; 1840(6):2014-24. PMID: 24561157.
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    120. Annibale P, Gratton E. Advanced fluorescence microscopy methods for the real-time study of transcription and chromatin dynamics. Transcription. 2014; 5(2):e28425. PMID: 25764219.
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    121. Sharma H, Digman MA, Felsinger N, Gratton E, Khine M. Enhanced emission of fluorophores on shrink-induced wrinkled composite structures. Opt Mater Express. 2014; 4(4):753-763. PMID: 25383253.
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    122. Pozzi D, Marchini C, Cardarelli F, Salomone F, Coppola S, Montani M, Zabaleta ME, Digman MA, Gratton E, Colapicchioni V, Caracciolo G. Mechanistic evaluation of the transfection barriers involved in lipid-mediated gene delivery: interplay between nanostructure and composition. Biochim Biophys Acta. 2014 Mar; 1838(3):957-67. PMID: 24296066.
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    123. Chiu CL, Digman MA, Gratton E. Measuring actin flow in 3D cell protrusions. Biophys J. 2013 Oct 15; 105(8):1746-55. PMID: 24138850.
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    124. Gehricke JG, Polzonetti C, Caburian C, Gratton E. Prefrontal hemodynamic changes during cigarette smoking in young adult smokers with and without ADHD. Pharmacol Biochem Behav. 2013 Nov; 112:78-81. PMID: 24125785.
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    125. James NG, Digman MA, Ross JA, Barylko B, Wang L, Li J, Chen Y, Mueller JD, Gratton E, Albanesi JP, Jameson DM. A mutation associated with centronuclear myopathy enhances the size and stability of dynamin 2 complexes in cells. Biochim Biophys Acta. 2014 Jan; 1840(1):315-21. PMID: 24016602.
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    126. Chiu CL, Gratton E. Axial super resolution topography of focal adhesion by confocal microscopy. Microsc Res Tech. 2013 Oct; 76(10):1070-8. PMID: 23897846.
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    127. Chiu CL, Digman MA, Gratton E. Cell matrix remodeling ability shown by image spatial correlation. J Biophys. 2013; 2013:532030. PMID: 23935614.
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    128. Di Rienzo C, Gratton E, Beltram F, Cardarelli F. Fast spatiotemporal correlation spectroscopy to determine protein lateral diffusion laws in live cell membranes. Proc Natl Acad Sci U S A. 2013 Jul 23; 110(30):12307-12. PMID: 23836651.
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    129. Skinner JP, Swift KM, Ruan Q, Perfetto S, Gratton E, Tetin SY. Simplified confocal microscope for counting particles at low concentrations. Rev Sci Instrum. 2013 Jul; 84(7):074301. PMID: 23902088.
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    130. Cutrale F, Salih A, Gratton E. Spectral phasor approach for fingerprinting of photo-activatable fluorescent proteins Dronpa, Kaede and KikGR. Methods Appl Fluoresc. 2013 Jun 04; 1(3):035001. PMID: 29148446.
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    131. Altamore I, Lanzano L, Gratton E. Dual channel detection of ultra low concentration of bacteria in real time by scanning FCS. Meas Sci Technol. 2013 Jun 01; 24(6):65702. PMID: 24039347.
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    132. Conway DE, Breckenridge MT, Hinde E, Gratton E, Chen CS, Schwartz MA. Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Curr Biol. 2013 Jun 03; 23(11):1024-30. PMID: 23684974.
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    133. Golfetto O, Hinde E, Gratton E. Laurdan fluorescence lifetime discriminates cholesterol content from changes in fluidity in living cell membranes. Biophys J. 2013 Mar 19; 104(6):1238-47. PMID: 23528083.
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    134. Andrews LM, Jones MR, Digman MA, Gratton E. Detecting Pyronin Y labeled RNA transcripts in live cell microenvironments by phasor-FLIM analysis. Methods Appl Fluoresc. 2013 Mar 01; 1(1):015001. PMID: 24563776.
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    135. Krasieva TB, Stringari C, Liu F, Sun CH, Kong Y, Balu M, Meyskens FL, Gratton E, Tromberg BJ. Two-photon excited fluorescence lifetime imaging and spectroscopy of melanins in vitro and in vivo. J Biomed Opt. 2013 Mar; 18(3):31107. PMID: 23235925.
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    136. Coppola S, Cardarelli F, Pozzi D, Estrada LC, Digman MA, Gratton E, Bifone A, Marianecci C, Caracciolo G. The role of cytoskeleton networks on lipid-mediated delivery of DNA. Ther Deliv. 2013 Feb; 4(2):191-202. PMID: 23343159.
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    137. Li K, Markosyan RM, Zheng YM, Golfetto O, Bungart B, Li M, Ding S, He Y, Liang C, Lee JC, Gratton E, Cohen FS, Liu SL. IFITM proteins restrict viral membrane hemifusion. PLoS Pathog. 2013 Jan; 9(1):e1003124. PMID: 23358889.
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    138. Dobrinskikh E, Lanzano L, Rachelson J, Cranston D, Moldovan R, Lei T, Gratton E, Doctor RB. Shank2 contributes to the apical retention and intracellular redistribution of NaPiIIa in OK cells. Am J Physiol Cell Physiol. 2013 Mar; 304(6):C561-73. PMID: 23325414.
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    139. Chen H, Gratton E. A practical implementation of multifrequency widefield frequency-domain fluorescence lifetime imaging microscopy. Microsc Res Tech. 2013 Mar; 76(3):282-9. PMID: 23296945.
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    140. Adu-Gyamfi E, Soni SP, Xue Y, Digman MA, Gratton E, Stahelin RV. The Ebola virus matrix protein penetrates into the plasma membrane: a key step in viral protein 40 (VP40) oligomerization and viral egress. J Biol Chem. 2013 Feb 22; 288(8):5779-89. PMID: 23297401.
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    141. Digman MA, Stakic M, Gratton E. Raster image correlation spectroscopy and number and brightness analysis. Methods Enzymol. 2013; 518:121-44. PMID: 23276538.
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    142. Leproux A, Durkin A, Compton M, Cerussi AE, Gratton E, Tromberg BJ. Assessing tumor contrast in radiographically dense breast tissue using Diffuse Optical Spectroscopic Imaging (DOSI). Breast Cancer Res. 2013; 15(5):R89. PMID: 24066941.
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    143. Cutrale F, Salih A, Gratton E. Spectral Phasor approach for fingerprinting of photo-activatable fluorescent proteins Dronpa, Kaede and KikGR. Methods Appl Fluoresc. 2013; 1(3):35001. PMID: 24040513.
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    144. Coppola S, Pozzi D, De Sanctis SC, Digman MA, Gratton E, Caracciolo G. Quantitative measurement of intracellular transport of nanocarriers by spatio-temporal image correlation spectroscopy. Methods Appl Fluoresc. 2013; 1(1). PMID: 24376913.
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    145. Hinde E, Cardarelli F, Chen A, Khine M, Gratton E. Tracking the mechanical dynamics of human embryonic stem cell chromatin. Epigenetics Chromatin. 2012 Dec 21; 5(1):20. PMID: 23259580.
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    146. Andrews LM, Jones MR, Digman MA, Gratton E. Spectral phasor analysis of Pyronin Y labeled RNA microenvironments in living cells. Biomed Opt Express. 2013 Jan 01; 4(1):171-7. PMID: 23304656.
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    147. Hinde E, Digman MA, Hahn KM, Gratton E. Millisecond spatiotemporal dynamics of FRET biosensors by the pair correlation function and the phasor approach to FLIM. Proc Natl Acad Sci U S A. 2013 Jan 02; 110(1):135-40. PMID: 23248275.
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    148. Torno K, Wright BK, Jones MR, Digman MA, Gratton E, Phillips M. Real-time analysis of metabolic activity within Lactobacillus acidophilus by phasor fluorescence lifetime imaging microscopy of NADH. Curr Microbiol. 2013 Apr; 66(4):365-7. PMID: 23233088.
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    149. Wigal SB, Polzonetti CM, Stehli A, Gratton E. Phase synchronization of oxygenation waves in the frontal areas of children with attention-deficit hyperactivity disorder detected by optical diffusion spectroscopy correlates with medication. J Biomed Opt. 2012 Dec; 17(12):127002. PMID: 23232795.
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    150. Whiteside MD, Digman MA, Gratton E, Treseder KK. Organic nitrogen uptake by arbuscular mycorrhizal fungi in a boreal forest. Soil Biol Biochem. 2012 Dec; 55. PMID: 24371363.
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    151. Adu-Gyamfi E, Digman MA, Gratton E, Stahelin RV. Single-particle tracking demonstrates that actin coordinates the movement of the Ebola virus matrix protein. Biophys J. 2012 Nov 07; 103(9):L41-3. PMID: 23199932.
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    152. Stringari C, Nourse JL, Flanagan LA, Gratton E. Phasor fluorescence lifetime microscopy of free and protein-bound NADH reveals neural stem cell differentiation potential. PLoS One. 2012; 7(11):e48014. PMID: 23144844.
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    153. Crosignani V, Dvornikov A, Aguilar JS, Stringari C, Edwards R, Mantulin WW, Gratton E. Deep tissue fluorescence imaging and in vivo biological applications. J Biomed Opt. 2012 Nov; 17(11):116023. PMID: 23214184.
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    154. Wright BK, Andrews LM, Jones MR, Stringari C, Digman MA, Gratton E. Phasor-FLIM analysis of NADH distribution and localization in the nucleus of live progenitor myoblast cells. Microsc Res Tech. 2012 Dec; 75(12):1717-22. PMID: 23019116.
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    155. Arnesano C, Santoro Y, Gratton E. Digital parallel frequency-domain spectroscopy for tissue imaging. J Biomed Opt. 2012 Sep; 17(9):96014-1. PMID: 23085915.
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    156. Giral H, Cranston D, Lanzano L, Caldas Y, Sutherland E, Rachelson J, Dobrinskikh E, Weinman EJ, Doctor RB, Gratton E, Levi M. NHE3 regulatory factor 1 (NHERF1) modulates intestinal sodium-dependent phosphate transporter (NaPi-2b) expression in apical microvilli. J Biol Chem. 2012 Oct 12; 287(42):35047-56. PMID: 22904329.
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    157. Coppola S, Estrada LC, Digman MA, Pozzi D, Cardarelli F, Gratton E, Caracciolo G. Intracellular trafficking of cationic liposome-DNA complexes in living cells. Soft Matter. 2012 Aug 14; 8(30):7919-7927. PMID: 25152766.
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    158. Stringari C, Edwards RA, Pate KT, Waterman ML, Donovan PJ, Gratton E. Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH. Sci Rep. 2012; 2:568. PMID: 22891156.
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    159. Wright BK, Andrews LM, Markham J, Jones MR, Stringari C, Digman MA, Gratton E. NADH distribution in live progenitor stem cells by phasor-fluorescence lifetime image microscopy. Biophys J. 2012 Jul 03; 103(1):L7-9. PMID: 22828352.
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    160. Cutrale F, Gratton E. Inclined selective plane illumination microscopy adaptor for conventional microscopes. Microsc Res Tech. 2012 Nov; 75(11):1461-6. PMID: 22736488.
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    161. Adu-Gyamfi E, Digman MA, Gratton E, Stahelin RV. Investigation of Ebola VP40 assembly and oligomerization in live cells using number and brightness analysis. Biophys J. 2012 Jun 06; 102(11):2517-25. PMID: 22713567.
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    162. James NG, Digman MA, Gratton E, Barylko B, Ding X, Albanesi JP, Goldberg MS, Jameson DM. Number and brightness analysis of LRRK2 oligomerization in live cells. Biophys J. 2012 Jun 06; 102(11):L41-3. PMID: 22713584.
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    163. Cardarelli F, Lanzano L, Gratton E. Capturing directed molecular motion in the nuclear pore complex of live cells. Proc Natl Acad Sci U S A. 2012 Jun 19; 109(25):9863-8. PMID: 22665783.
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    164. Sanchez SA, Tricerri MA, Gratton E. Laurdan generalized polarization fluctuations measures membrane packing micro-heterogeneity in vivo. Proc Natl Acad Sci U S A. 2012 May 08; 109(19):7314-9. PMID: 22529342.
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    165. Battisti A, Digman MA, Gratton E, Storti B, Beltram F, Bizzarri R. Intracellular pH measurements made simple by fluorescent protein probes and the phasor approach to fluorescence lifetime imaging. Chem Commun (Camb). 2012 May 25; 48(42):5127-9. PMID: 22517076.
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    166. Lanzano L, Gratton E. Measurement of distance with the nanoscale precise imaging by rapid beam oscillation method. Microsc Res Tech. 2012 Sep; 75(9):1253-64. PMID: 22514034.
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    167. Stringari C, Sierra R, Donovan PJ, Gratton E. Label-free separation of human embryonic stem cells and their differentiating progenies by phasor fluorescence lifetime microscopy. J Biomed Opt. 2012 Apr; 17(4):046012. PMID: 22559690.
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    168. Zhou S, Lo WC, Suhalim JL, Digman MA, Gratton E, Nie Q, Lander AD. Free extracellular diffusion creates the Dpp morphogen gradient of the Drosophila wing disc. Curr Biol. 2012 Apr 24; 22(8):668-75. PMID: 22445299.
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    169. Digman MA, Gratton E. Scanning image correlation spectroscopy. Bioessays. 2012 May; 34(5):377-85. PMID: 22415853.
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    170. Hinde E, Cardarelli F, Digman MA, Gratton E. Changes in chromatin compaction during the cell cycle revealed by micrometer-scale measurement of molecular flow in the nucleus. Biophys J. 2012 Feb 08; 102(3):691-7. PMID: 22325293.
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    171. Estrada LC, Gratton E. Spectroscopic properties of gold nanoparticles at the single-particle level in biological environments. Chemphyschem. 2012 Mar; 13(4):1087-92. PMID: 22298327.
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    172. Kniazeva E, Weidling JW, Singh R, Botvinick EL, Digman MA, Gratton E, Putnam AJ. Quantification of local matrix deformations and mechanical properties during capillary morphogenesis in 3D. Integr Biol (Camb). 2012 Apr; 4(4):431-9. PMID: 22281872.
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    173. Sanchez SA, Gratton E, Zanocco AL, Lemp E, Gunther G. Sucrose monoester micelles size determined by Fluorescence Correlation Spectroscopy (FCS). PLoS One. 2011; 6(12):e29278. PMID: 22216230.
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    174. Stafford RL, Hinde E, Knight MJ, Pennella MA, Ear J, Digman MA, Gratton E, Bowie JU. Tandem SAM domain structure of human Caskin1: a presynaptic, self-assembling scaffold for CASK. Structure. 2011 Dec 07; 19(12):1826-36. PMID: 22153505.
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    175. Leproux A, Cerussi AE, Tanamai W, Durkin AF, Compton M, Gratton E, Tromberg BJ. Impact of contralateral and ipsilateral reference tissue selection on self-referencing differential spectroscopy for breast cancer detection. J Biomed Opt. 2011 Nov; 16(11):116019. PMID: 22112124.
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    176. Estrada LC, Gratton E. 3D nanometer images of biological fibers by directed motion of gold nanoparticles. Nano Lett. 2011 Nov 09; 11(11):4656-60. PMID: 21919444.
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    177. Santoro Y, Leproux A, Cerussi A, Tromberg B, Gratton E. Breast cancer spatial heterogeneity in near-infrared spectra and the prediction of neoadjuvant chemotherapy response. J Biomed Opt. 2011 Sep; 16(9):097007. PMID: 21950942.
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    178. Hinde E, Digman MA, Welch C, Hahn KM, Gratton E. Biosensor Förster resonance energy transfer detection by the phasor approach to fluorescence lifetime imaging microscopy. Microsc Res Tech. 2012 Mar; 75(3):271-81. PMID: 21858900.
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    179. Cardarelli F, Lanzano L, Gratton E. Fluorescence correlation spectroscopy of intact nuclear pore complexes. Biophys J. 2011 Aug 17; 101(4):L27-9. PMID: 21843462.
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    180. Wolf U, Toronov V, Choi JH, Gupta R, Michalos A, Gratton E, Wolf M. Correlation of functional and resting state connectivity of cerebral oxy-, deoxy-, and total hemoglobin concentration changes measured by near-infrared spectrophotometry. J Biomed Opt. 2011 Aug; 16(8):087013. PMID: 21895340.
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    181. Stringari C, Cinquin A, Cinquin O, Digman MA, Donovan PJ, Gratton E. Phasor approach to fluorescence lifetime microscopy distinguishes different metabolic states of germ cells in a live tissue. Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33):13582-7. PMID: 21808026.
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    182. Sanchez S, Bakás L, Gratton E, Herlax V. Alpha hemolysin induces an increase of erythrocytes calcium: a FLIM 2-photon phasor analysis approach. PLoS One. 2011; 6(6):e21127. PMID: 21698153.
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    183. Itano MS, Neumann AK, Liu P, Zhang F, Gratton E, Parak WJ, Thompson NL, Jacobson K. DC-SIGN and influenza hemagglutinin dynamics in plasma membrane microdomains are markedly different. Biophys J. 2011 Jun 08; 100(11):2662-70. PMID: 21641311.
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    184. Caracciolo G, Pozzi D, Capriotti AL, Marianecci C, Carafa M, Marchini C, Montani M, Amici A, Amenitsch H, Digman MA, Gratton E, Sanchez SS, Laganà A. Factors determining the superior performance of lipid/DNA/protammine nanoparticles over lipoplexes. J Med Chem. 2011 Jun 23; 54(12):4160-71. PMID: 21615134.
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    185. Kotlarchyk MA, Shreim SG, Alvarez-Elizondo MB, Estrada LC, Singh R, Valdevit L, Kniazeva E, Gratton E, Putnam AJ, Botvinick EL. Concentration independent modulation of local micromechanics in a fibrin gel. PLoS One. 2011; 6(5):e20201. PMID: 21629793.
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    186. Lanzano L, Lei T, Okamura K, Giral H, Caldas Y, Masihzadeh O, Gratton E, Levi M, Blaine J. Differential modulation of the molecular dynamics of the type IIa and IIc sodium phosphate cotransporters by parathyroid hormone. Am J Physiol Cell Physiol. 2011 Oct; 301(4):C850-61. PMID: 21593452.
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    187. Sanchez SA, Gunther G, Tricerri MA, Gratton E. Methyl-ß-cyclodextrins preferentially remove cholesterol from the liquid disordered phase in giant unilamellar vesicles. J Membr Biol. 2011 May; 241(1):1-10. PMID: 21468650.
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    188. Hinde E, Cardarelli F, Digman MA, Kershner A, Kimble J, Gratton E. The impact of mitotic versus interphase chromatin architecture on the molecular flow of EGFP by pair correlation analysis. Biophys J. 2011 Apr 06; 100(7):1829-36. PMID: 21463597.
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    189. Lanzano L, Digman MA, Fwu P, Giral H, Levi M, Gratton E. Nanometer-scale imaging by the modulation tracking method. J Biophotonics. 2011 Jun; 4(6):415-24. PMID: 21462350.
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    190. Azartash K, Kwan J, Paugh JR, Nguyen AL, Jester JV, Gratton E. Pre-corneal tear film thickness in humans measured with a novel technique. Mol Vis. 2011 Mar 22; 17:756-67. PMID: 21527997.
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    191. Crosignani V, Dvornikov AS, Gratton E. Enhancement of imaging depth in turbid media using a wide area detector. J Biophotonics. 2011 Sep; 4(9):592-9. PMID: 21425242.
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    192. Marchini C, Pozzi D, Montani M, Alfonsi C, Amici A, Candeloro De Sanctis S, Digman MA, Sanchez S, Gratton E, Amenitsch H, Fabbretti A, Gualerzi CO, Caracciolo G. Role of temperature-independent lipoplex-cell membrane interactions in the efficiency boost of multicomponent lipoplexes. Cancer Gene Ther. 2011 Aug; 18(8):543-52. PMID: 21394110.
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    193. Giral H, Lanzano L, Caldas Y, Blaine J, Verlander JW, Lei T, Gratton E, Levi M. Role of PDZK1 protein in apical membrane expression of renal sodium-coupled phosphate transporters. J Biol Chem. 2011 Apr 29; 286(17):15032-42. PMID: 21388960.
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    194. Blaine J, Lanzano L, Giral H, Caldas Y, Levi M, Gratton E, Moldovan R, Lei T. Dynamic imaging of the sodium phosphate cotransporters. Adv Chronic Kidney Dis. 2011 Mar; 18(2):145-50. PMID: 21406299.
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    195. Gratton E. Applied physics. Deeper tissue imaging with total detection. Science. 2011 Feb 25; 331(6020):1016-7. PMID: 21350154.
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    196. Chen B, Estrada LC, Hellriegel C, Gratton E. Nanometer-scale optical imaging of collagen fibers using gold nanoparticles. Biomed Opt Express. 2011 Feb 07; 2(3):511-9. PMID: 21412457.
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    197. Choi CK, Zareno J, Digman MA, Gratton E, Horwitz AR. Cross-correlated fluctuation analysis reveals phosphorylation-regulated paxillin-FAK complexes in nascent adhesions. Biophys J. 2011 Feb 02; 100(3):583-592. PMID: 21281572.
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    198. Ross JA, Digman MA, Wang L, Gratton E, Albanesi JP, Jameson DM. Oligomerization state of dynamin 2 in cell membranes using TIRF and number and brightness analysis. Biophys J. 2011 Feb 02; 100(3):L15-L17. PMID: 21281565.
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    199. Vetri V, Ossato G, Militello V, Digman MA, Leone M, Gratton E. Fluctuation methods to study protein aggregation in live cells: concanavalin A oligomers formation. Biophys J. 2011 Feb 02; 100(3):774-783. PMID: 21281593.
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    200. Digman MA, Gratton E. Lessons in fluctuation correlation spectroscopy. Annu Rev Phys Chem. 2011; 62:645-68. PMID: 21219151.
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    201. Behne MJ, Sanchez S, Barry NP, Kirschner N, Meyer W, Mauro TM, Moll I, Gratton E. Major translocation of calcium upon epidermal barrier insult: imaging and quantification via FLIM/Fourier vector analysis. Arch Dermatol Res. 2011 Mar; 303(2):103-15. PMID: 21193994.
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    202. Kim SA, Sanabria H, Digman MA, Gratton E, Schwille P, Zipfel WR, Waxham MN. Quantifying translational mobility in neurons: comparison between current optical techniques. J Neurosci. 2010 Dec 08; 30(49):16409-16. PMID: 21147979.
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    203. Rossow MJ, Sasaki JM, Digman MA, Gratton E. Raster image correlation spectroscopy in live cells. Nat Protoc. 2010 Nov; 5(11):1761-74. PMID: 21030952.
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    204. Azartash K, Shy CJ, Flynn K, Jester JV, Gratton E. Non-invasive in vivo measurement of the tear film using spatial autocorrelation in a live mammal model. Biomed Opt Express. 2010 Oct 08; 1(4):1127-1137. PMID: 21258535.
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    205. Hinde E, Cardarelli F, Digman MA, Gratton E. In vivo pair correlation analysis of EGFP intranuclear diffusion reveals DNA-dependent molecular flow. Proc Natl Acad Sci U S A. 2010 Sep 21; 107(38):16560-5. PMID: 20823232.
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    206. Moens PD, Gratton E, Salvemini IL. Fluorescence correlation spectroscopy, raster image correlation spectroscopy, and number and brightness on a commercial confocal laser scanning microscope with analog detectors (Nikon C1). Microsc Res Tech. 2011 Apr; 74(4):377-88. PMID: 20734406.
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    207. Ossato G, Digman MA, Aiken C, Lukacsovich T, Marsh JL, Gratton E. A two-step path to inclusion formation of huntingtin peptides revealed by number and brightness analysis. Biophys J. 2010 Jun 16; 98(12):3078-85. PMID: 20550921.
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    208. Cardarelli F, Gratton E. In vivo imaging of single-molecule translocation through nuclear pore complexes by pair correlation functions. PLoS One. 2010 May 03; 5(5):e10475. PMID: 20454622.
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    209. Sánchez SA, Tricerri MA, Ossato G, Gratton E. Lipid packing determines protein-membrane interactions: challenges for apolipoprotein A-I and high density lipoproteins. Biochim Biophys Acta. 2010 Jul; 1798(7):1399-408. PMID: 20347719.
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    210. Celli A, Sanchez S, Behne M, Hazlett T, Gratton E, Mauro T. The epidermal Ca(2+) gradient: Measurement using the phasor representation of fluorescent lifetime imaging. Biophys J. 2010 Mar 03; 98(5):911-21. PMID: 20197045.
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    211. Rossow MJ, Mantulin WW, Gratton E. Scanning laser image correlation for measurement of flow. J Biomed Opt. 2010 Mar-Apr; 15(2):026003. PMID: 20459248.
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    212. Kukreti S, Cerussi AE, Tanamai W, Hsiang D, Tromberg BJ, Gratton E. Characterization of metabolic differences between benign and malignant tumors: high-spectral-resolution diffuse optical spectroscopy. Radiology. 2010 Jan; 254(1):277-84. PMID: 20032159.
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    213. Celli A, Gratton E. Dynamics of lipid domain formation: fluctuation analysis. Biochim Biophys Acta. 2010 Jul; 1798(7):1368-76. PMID: 20025848.
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    214. Yoon Y, Tong J, Lee PJ, Albanese A, Bhardwaj N, Källberg M, Digman MA, Lu H, Gratton E, Shin YK, Cho W. Molecular basis of the potent membrane-remodeling activity of the epsin 1 N-terminal homology domain. J Biol Chem. 2010 Jan 01; 285(1):531-40. PMID: 19880963.
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    215. Tanner K, Ferris DR, Lanzano L, Mandefro B, Mantulin WW, Gardiner DM, Rugg EL, Gratton E. Coherent movement of cell layers during wound healing by image correlation spectroscopy. Biophys J. 2009 Oct 07; 97(7):2098-106. PMID: 19804742.
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    216. Katayama Y, Burkacky O, Meyer M, Bräuchle C, Gratton E, Lamb DC. Real-time nanomicroscopy via three-dimensional single-particle tracking. Chemphyschem. 2009 Oct 05; 10(14):2458-64. PMID: 19760694.
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    217. Digman MA, Gratton E. Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy. Wiley Interdiscip Rev Syst Biol Med. 2009 Sep-Oct; 1(2):273-282. PMID: 20835996.
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    218. Digman MA, Gratton E. Imaging barriers to diffusion by pair correlation functions. Biophys J. 2009 Jul 22; 97(2):665-73. PMID: 19619481.
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    219. Krishnan K, Holub O, Gratton E, Clayton AH, Cody S, Moens PD. Profilin interaction with phosphatidylinositol (4,5)-bisphosphate destabilizes the membrane of giant unilamellar vesicles. Biophys J. 2009 Jun 17; 96(12):5112-21. PMID: 19527671.
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    220. Gielen E, Smisdom N, vandeVen M, De Clercq B, Gratton E, Digman M, Rigo JM, Hofkens J, Engelborghs Y, Ameloot M. Measuring diffusion of lipid-like probes in artificial and natural membranes by raster image correlation spectroscopy (RICS): use of a commercial laser-scanning microscope with analog detection. Langmuir. 2009 May 05; 25(9):5209-18. PMID: 19260653.
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    221. Caracciolo G, Caminiti R, Digman MA, Gratton E, Sanchez S. Efficient escape from endosomes determines the superior efficiency of multicomponent lipoplexes. J Phys Chem B. 2009 Apr 16; 113(15):4995-7. PMID: 19301832.
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    222. Digman MA, Gratton E. Analysis of diffusion and binding in cells using the RICS approach. Microsc Res Tech. 2009 Apr; 72(4):323-32. PMID: 19067357.
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    223. Rossow M, Mantulin WW, Gratton E. Spatiotemporal image correlation spectroscopy measurements of flow demonstrated in microfluidic channels. J Biomed Opt. 2009 Mar-Apr; 14(2):024014. PMID: 19405744.
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    224. Hellriegel C, Gratton E. Real-time multi-parameter spectroscopy and localization in three-dimensional single-particle tracking. J R Soc Interface. 2009 Feb 06; 6 Suppl 1:S3-14. PMID: 18753123.
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    225. Gratton E, Digman M. One photon up, one photon down. Nat Biotechnol. 2009 Feb; 27(2):147-8. PMID: 19204693.
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    226. Digman MA, Wiseman PW, Choi C, Horwitz AR, Gratton E. Stoichiometry of molecular complexes at adhesions in living cells. Proc Natl Acad Sci U S A. 2009 Feb 17; 106(7):2170-5. PMID: 19168634.
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    227. Digman MA, Wiseman PW, Horwitz AR, Gratton E. Detecting protein complexes in living cells from laser scanning confocal image sequences by the cross correlation raster image spectroscopy method. Biophys J. 2009 Jan; 96(2):707-16. PMID: 19167315.
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    228. Toro C, Sanchez SA, Zanocco A, Lemp E, Gratton E, Gunther G. Solubilization of lipid bilayers by myristyl sucrose ester: effect of cholesterol and phospholipid head group size. Chem Phys Lipids. 2009 Feb; 157(2):104-12. PMID: 19071100.
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    229. Barreiro O, Zamai M, Yáñez-Mó M, Tejera E, López-Romero P, Monk PN, Gratton E, Caiolfa VR, Sánchez-Madrid F. Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms. J Cell Biol. 2008 Nov 03; 183(3):527-42. PMID: 18955551.
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    230. Sanabria H, Digman MA, Gratton E, Waxham MN. Spatial diffusivity and availability of intracellular calmodulin. Biophys J. 2008 Dec 15; 95(12):6002-15. PMID: 18820232.
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    231. Unruh JR, Gratton E. Analysis of molecular concentration and brightness from fluorescence fluctuation data with an electron multiplied CCD camera. Biophys J. 2008 Dec; 95(11):5385-98. PMID: 18805922.
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    232. Malengo G, Andolfo A, Sidenius N, Gratton E, Zamai M, Caiolfa VR. Fluorescence correlation spectroscopy and photon counting histogram on membrane proteins: functional dynamics of the glycosylphosphatidylinositol-anchored urokinase plasminogen activator receptor. J Biomed Opt. 2008 May-Jun; 13(3):031215. PMID: 18601539.
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    233. Colyer RA, Lee C, Gratton E. A novel fluorescence lifetime imaging system that optimizes photon efficiency. Microsc Res Tech. 2008 Mar; 71(3):201-13. PMID: 18008362.
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    234. Kwok S, Lee C, Sánchez SA, Hazlett TL, Gratton E, Hayashi Y. Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity. Biochem Biophys Res Commun. 2008 May 02; 369(2):519-25. PMID: 18302935.
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    235. Kukreti S, Cerussi A, Tromberg B, Gratton E. Intrinsic near-infrared spectroscopic markers of breast tumors. Dis Markers. 2008; 25(6):281-90. PMID: 19208946.
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    236. Dalal RB, Digman MA, Horwitz AF, Vetri V, Gratton E. Determination of particle number and brightness using a laser scanning confocal microscope operating in the analog mode. Microsc Res Tech. 2008 Jan; 71(1):69-81. PMID: 17937391.
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    237. Levi V, Gratton E. Chromatin dynamics during interphase explored by single-particle tracking. Chromosome Res. 2008; 16(3):439-49. PMID: 18461483.
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    238. Fiorini R, Ragni L, Ambrosi S, Littarru GP, Gratton E, Hazlett T. Fluorescence studies of the interactions of ubiquinol-10 with liposomes. Photochem Photobiol. 2008 Jan-Feb; 84(1):209-14. PMID: 18173722.
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    239. Brown CM, Dalal RB, Hebert B, Digman MA, Horwitz AR, Gratton E. Raster image correlation spectroscopy (RICS) for measuring fast protein dynamics and concentrations with a commercial laser scanning confocal microscope. J Microsc. 2008 Jan; 229(Pt 1):78-91. PMID: 18173647.
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    240. Digman MA, Dalal R, Horwitz AF, Gratton E. Mapping the number of molecules and brightness in the laser scanning microscope. Biophys J. 2008 Mar 15; 94(6):2320-32. PMID: 18096627.
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    241. García-Marcos A, Sánchez SA, Parada P, Eid J, Jameson DM, Remacha M, Gratton E, Ballesta JP. Yeast ribosomal stalk heterogeneity in vivo shown by two-photon FCS and molecular brightness analysis. Biophys J. 2008 Apr 01; 94(7):2884-90. PMID: 18096629.
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    242. Raub CB, Unruh J, Suresh V, Krasieva T, Lindmo T, Gratton E, Tromberg BJ, George SC. Image correlation spectroscopy of multiphoton images correlates with collagen mechanical properties. Biophys J. 2008 Mar 15; 94(6):2361-73. PMID: 18065452.
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    243. Caiolfa VR, Zamai M, Malengo G, Andolfo A, Madsen CD, Sutin J, Digman MA, Gratton E, Blasi F, Sidenius N. Monomer dimer dynamics and distribution of GPI-anchored uPAR are determined by cell surface protein assemblies. J Cell Biol. 2007 Dec 03; 179(5):1067-82. PMID: 18056417.
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    244. Olopade CO, Mensah E, Gupta R, Huo D, Picchietti DL, Gratton E, Michalos A. Noninvasive determination of brain tissue oxygenation during sleep in obstructive sleep apnea: a near-infrared spectroscopic approach. Sleep. 2007 Dec; 30(12):1747-55. PMID: 18246984.
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    245. Digman MA, Brown CM, Horwitz AR, Mantulin WW, Gratton E. Paxillin dynamics measured during adhesion assembly and disassembly by correlation spectroscopy. Biophys J. 2008 Apr 01; 94(7):2819-31. PMID: 17993500.
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    246. Digman MA, Caiolfa VR, Zamai M, Gratton E. The phasor approach to fluorescence lifetime imaging analysis. Biophys J. 2008 Jan 15; 94(2):L14-6. PMID: 17981902.
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    247. Wolf U, Wolf M, Choi JH, Paunescu LA, Michalos A, Gratton E. Regional differences of hemodynamics and oxygenation in the human calf muscle detected with near-infrared spectrophotometry. J Vasc Interv Radiol. 2007 Sep; 18(9):1094-101. PMID: 17804770.
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    248. Celli A, Beretta S, Gratton E. Phase fluctuations on the micron-submicron scale in GUVs composed of a binary lipid mixture. Biophys J. 2008 Jan 01; 94(1):104-16. PMID: 17766332.
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    249. Sanchez SA, Tricerri MA, Gratton E. Interaction of high density lipoprotein particles with membranes containing cholesterol. J Lipid Res. 2007 Aug; 48(8):1689-700. PMID: 17485728.
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    250. Gatto R, Hoffman W, Paisansathan C, Mantulin W, Gratton E, Charbel FT. Effect of age on brain oxygenation regulation during changes in position. J Neurosci Methods. 2007 Aug 30; 164(2):308-11. PMID: 17561266.
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    251. Kukreti S, Cerussi A, Tromberg B, Gratton E. Intrinsic tumor biomarkers revealed by novel double-differential spectroscopic analysis of near-infrared spectra. J Biomed Opt. 2007 Mar-Apr; 12(2):020509. PMID: 17477706.
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    252. Boens N, Qin W, Basaric N, Hofkens J, Ameloot M, Pouget J, Lefèvre JP, Valeur B, Gratton E, vandeVen M, Silva ND, Engelborghs Y, Willaert K, Sillen A, Rumbles G, Phillips D, Visser AJ, van Hoek A, Lakowicz JR, Malak H, Gryczynski I, Szabo AG, Krajcarski DT, Tamai N, Miura A. Fluorescence lifetime standards for time and frequency domain fluorescence spectroscopy. Anal Chem. 2007 Mar 01; 79(5):2137-49. PMID: 17269654.
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    253. Calderon-Arnulphi M, Alaraj A, Amin-Hanjani S, Mantulin WW, Polzonetti CM, Gratton E, Charbel FT. Detection of cerebral ischemia in neurovascular surgery using quantitative frequency-domain near-infrared spectroscopy. J Neurosurg. 2007 Feb; 106(2):283-90. PMID: 17410713.
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    254. Celli A, Lee CY, Gratton E. Fluorescence microscopy to study pressure between lipids in giant unilamellar vesicles. Methods Mol Biol. 2007; 400:333-9. PMID: 17951744.
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    255. Levi V, Gratton E. Exploring dynamics in living cells by tracking single particles. Cell Biochem Biophys. 2007; 48(1):1-15. PMID: 17703064.
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    256. Tanner K, Beitel E, D'Amico E, Mantulin WW, Gratton E. Effects of vasodilation on intrinsic optical signals in the mammalian brain: a phantom study. J Biomed Opt. 2006 Nov-Dec; 11(6):064020. PMID: 17212543.
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    257. Eckhoff DA, Stuart JN, Sutin JD, Sweedler JV, Gratton E. Capillary electrophoresis of ultrasmall carboxylate functionalized silicon nanoparticles. J Chem Phys. 2006 Aug 28; 125(8):081103. PMID: 16964993.
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    258. Nicolini C, Celli A, Gratton E, Winter R. Pressure tuning of the morphology of heterogeneous lipid vesicles: a two-photon-excitation fluorescence microscopy study. Biophys J. 2006 Oct 15; 91(8):2936-42. PMID: 16877511.
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    259. Hanson KM, Gratton E, Bardeen CJ. Sunscreen enhancement of UV-induced reactive oxygen species in the skin. Free Radic Biol Med. 2006 Oct 15; 41(8):1205-12. PMID: 17015167.
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    260. Ragan T, Huang H, So P, Gratton E. 3D particle tracking on a two-photon microscope. J Fluoresc. 2006 May; 16(3):325-36. PMID: 16544202.
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    261. Nicolini C, Baranski J, Schlummer S, Palomo J, Lumbierres-Burgues M, Kahms M, Kuhlmann J, Sanchez S, Gratton E, Waldmann H, Winter R. Visualizing association of N-ras in lipid microdomains: influence of domain structure and interfacial adsorption. J Am Chem Soc. 2006 Jan 11; 128(1):192-201. PMID: 16390147.
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    262. Simonson P, D'Amico E, Gratton E. Modulation of an optical needle's reflectivity alters the average photon path through scattering media. J Biomed Opt. 2006 Jan-Feb; 11(1):014023. PMID: 16526900.
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    263. Levi V, Gelfand VI, Serpinskaya AS, Gratton E. Melanosomes transported by myosin-V in Xenopus melanophores perform slow 35 nm steps. Biophys J. 2006 Jan 01; 90(1):L07-9. PMID: 16284273.
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    264. Tanner K, D'Amico E, Kaczmarowski A, Kukreti S, Malpeli J, Mantulin WW, Gratton E. Spectrally resolved neurophotonics: a case report of hemodynamics and vascular components in the mammalian brain. J Biomed Opt. 2005 Nov-Dec; 10(6):064009. PMID: 16409074.
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    265. Eckhoff DA, Sutin JD, Clegg RM, Gratton E, Rogozhina EV, Braun PV. Optical characterization of ultrasmall Si nanoparticles prepared through electrochemical dispersion of bulk Si. J Phys Chem B. 2005 Oct 27; 109(42):19786-97. PMID: 16853559.
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    266. Gokhale NA, Abraham A, Digman MA, Gratton E, Cho W. Phosphoinositide specificity of and mechanism of lipid domain formation by annexin A2-p11 heterotetramer. J Biol Chem. 2005 Dec 30; 280(52):42831-40. PMID: 16230353.
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    267. Levi V, Serpinskaya AS, Gratton E, Gelfand V. Organelle transport along microtubules in Xenopus melanophores: evidence for cooperation between multiple motors. Biophys J. 2006 Jan 01; 90(1):318-27. PMID: 16214870.
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    268. Levi V, Ruan Q, Plutz M, Belmont AS, Gratton E. Chromatin dynamics in interphase cells revealed by tracking in a two-photon excitation microscope. Biophys J. 2005 Dec; 89(6):4275-85. PMID: 16150965.
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    269. Sánchez SA, Gratton E. Lipid--protein interactions revealed by two-photon microscopy and fluorescence correlation spectroscopy. Acc Chem Res. 2005 Jun; 38(6):469-77. PMID: 15966713.
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    270. Digman MA, Brown CM, Sengupta P, Wiseman PW, Horwitz AR, Gratton E. Measuring fast dynamics in solutions and cells with a laser scanning microscope. Biophys J. 2005 Aug; 89(2):1317-27. PMID: 15908582.
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    271. Arnulphi C, Sánchez SA, Tricerri MA, Gratton E, Jonas A. Interaction of human apolipoprotein A-I with model membranes exhibiting lipid domains. Biophys J. 2005 Jul; 89(1):285-95. PMID: 15849246.
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    272. Digman MA, Sengupta P, Wiseman PW, Brown CM, Horwitz AR, Gratton E. Fluctuation correlation spectroscopy with a laser-scanning microscope: exploiting the hidden time structure. Biophys J. 2005 May; 88(5):L33-6. PMID: 15792971.
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    273. Tricerri MA, Toledo JD, Sanchez SA, Hazlett TL, Gratton E, Jonas A, Garda HA. Visualization and analysis of apolipoprotein A-I interaction with binary phospholipid bilayers. J Lipid Res. 2005 Apr; 46(4):669-78. PMID: 15654128.
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    274. Levi V, Ruan Q, Gratton E. 3-D particle tracking in a two-photon microscope: application to the study of molecular dynamics in cells. Biophys J. 2005 Apr; 88(4):2919-28. PMID: 15653748.
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    275. Gratton E, Toronov V, Wolf U, Wolf M, Webb A. Measurement of brain activity by near-infrared light. J Biomed Opt. 2005 Jan-Feb; 10(1):11008. PMID: 15847574.
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    276. Safonova LP, Michalos A, Wolf U, Wolf M, Hueber DM, Choi JH, Gupta R, Polzonetti C, Mantulin WW, Gratton E. Age-correlated changes in cerebral hemodynamics assessed by near-infrared spectroscopy. Arch Gerontol Geriatr. 2004 Nov-Dec; 39(3):207-25. PMID: 15381340.
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    277. Barcellona ML, Gammon S, Hazlett T, Digman MA, Gratton E. Polarized fluorescence correlation spectroscopy of DNA-DAPI complexes. Microsc Res Tech. 2004 Nov; 65(4-5):205-17. PMID: 15630690.
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    278. Masters BR, So PT, Buehler C, Barry N, Sutin JD, Mantulin WW, Gratton E. Mitigating thermal mechanical damage potential during two-photon dermal imaging. J Biomed Opt. 2004 Nov-Dec; 9(6):1265-70. PMID: 15568947.
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    279. Inoue M, Digman MA, Cheng M, Breusegem SY, Halaihel N, Sorribas V, Mantulin WW, Gratton E, Barry NP, Levi M. Partitioning of NaPi cotransporter in cholesterol-, sphingomyelin-, and glycosphingolipid-enriched membrane domains modulates NaPi protein diffusion, clustering, and activity. J Biol Chem. 2004 Nov 19; 279(47):49160-71. PMID: 15355967.
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    280. Ruan Q, Cheng MA, Levi M, Gratton E, Mantulin WW. Spatial-temporal studies of membrane dynamics: scanning fluorescence correlation spectroscopy (SFCS). Biophys J. 2004 Aug; 87(2):1260-7. PMID: 15298928.
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    281. Janosch S, Nicolini C, Ludolph B, Peters C, Völkert M, Hazlet TL, Gratton E, Waldmann H, Winter R. Partitioning of dual-lipidated peptides into membrane microdomains: lipid sorting vs peptide aggregation. J Am Chem Soc. 2004 Jun 23; 126(24):7496-503. PMID: 15198596.
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    282. Czeslik C, Jansen R, Ballauff M, Wittemann A, Royer CA, Gratton E, Hazlett T. Mechanism of protein binding to spherical polyelectrolyte brushes studied in situ using two-photon excitation fluorescence fluctuation spectroscopy. Phys Rev E Stat Nonlin Soft Matter Phys. 2004 Feb; 69(2 Pt 1):021401. PMID: 14995438.
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    283. Morren G, Wolf U, Lemmerling P, Wolf M, Choi JH, Gratton E, De Lathauwer L, Van Huffel S. Detection of fast neuronal signals in the motor cortex from functional near infrared spectroscopy measurements using independent component analysis. Med Biol Eng Comput. 2004 Jan; 42(1):92-9. PMID: 14977228.
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    284. Kis-Petikova K, Gratton E. Distance measurement by circular scanning of the excitation beam in the two-photon microscope. Microsc Res Tech. 2004 Jan 01; 63(1):34-49. PMID: 14677132.
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    285. Choi J, Wolf M, Toronov V, Wolf U, Polzonetti C, Hueber D, Safonova LP, Gupta R, Michalos A, Mantulin W, Gratton E. Noninvasive determination of the optical properties of adult brain: near-infrared spectroscopy approach. J Biomed Opt. 2004 Jan-Feb; 9(1):221-9. PMID: 14715077.
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    286. Gaus K, Gratton E, Kable EP, Jones AS, Gelissen I, Kritharides L, Jessup W. Visualizing lipid structure and raft domains in living cells with two-photon microscopy. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15554-9. PMID: 14673117.
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    287. Toronov V, D'Amico E, Hueber D, Gratton E, Barbieri B, Webb A. Optimization of the signal-to-noise ratio of frequency-domain instrumentation for near-infrared spectro-imaging of the human brain. Opt Express. 2003 Oct 20; 11(21):2717-29. PMID: 19471386.
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    288. Müller JD, Gratton E. High-pressure fluorescence correlation spectroscopy. Biophys J. 2003 Oct; 85(4):2711-9. PMID: 14507734.
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    289. Levi V, Ruan Q, Kis-Petikova K, Gratton E. Scanning FCS, a novel method for three-dimensional particle tracking. Biochem Soc Trans. 2003 Oct; 31(Pt 5):997-1000. PMID: 14505467.
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    290. Toronov V, Walker S, Gupta R, Choi JH, Gratton E, Hueber D, Webb A. The roles of changes in deoxyhemoglobin concentration and regional cerebral blood volume in the fMRI BOLD signal. Neuroimage. 2003 Aug; 19(4):1521-31. PMID: 12948708.
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    291. Gratton E, Breusegem S, Sutin J, Ruan Q, Barry N. Fluorescence lifetime imaging for the two-photon microscope: time-domain and frequency-domain methods. J Biomed Opt. 2003 Jul; 8(3):381-90. PMID: 12880343.
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    292. Wolf M, Wolf U, Choi JH, Toronov V, Paunescu LA, Michalos A, Gratton E. Fast cerebral functional signal in the 100-ms range detected in the visual cortex by frequency-domain near-infrared spectrophotometry. Psychophysiology. 2003 Jul; 40(4):521-8. PMID: 14570160.
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    293. Behne MJ, Barry NP, Hanson KM, Aronchik I, Clegg RW, Gratton E, Feingold K, Holleran WM, Elias PM, Mauro TM. Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function. J Invest Dermatol. 2003 Jun; 120(6):998-1006. PMID: 12787127.
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    294. Wolf U, Wolf M, Choi JH, Levi M, Choudhury D, Hull S, Coussirat D, Paunescu LA, Safonova LP, Michalos A, Mantulin WW, Gratton E. Localized irregularities in hemoglobin flow and oxygenation in calf muscle in patients with peripheral vascular disease detected with near-infrared spectrophotometry. J Vasc Surg. 2003 May; 37(5):1017-26. PMID: 12756348.
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    295. Bagatolli LA, Sanchez SA, Hazlett T, Gratton E. Giant vesicles, Laurdan, and two-photon fluorescence microscopy: evidence of lipid lateral separation in bilayers. Methods Enzymol. 2003; 360:481-500. PMID: 12622164.
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    296. Zamai M, VandeVen M, Farao M, Gratton E, Ghiglieri A, Castelli MG, Fontana E, D'Argy R, Fiorino A, Pesenti E, Suarato A, Caiolfa VR. Camptothecin poly[n-(2-hydroxypropyl) methacrylamide] copolymers in antitopoisomerase-I tumor therapy: intratumor release and antitumor efficacy. Mol Cancer Ther. 2003 Jan; 2(1):29-40. PMID: 12533670.
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    297. Wolf M, Franceschini MA, Paunescu LA, Toronov V, Michalos A, Wolf U, Gratton E, Fantini S. Absolute frequency-domain pulse oximetry of the brain: methodology and measurements. Adv Exp Med Biol. 2003; 530:61-73. PMID: 14562705.
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    298. Wolf M, Wolf U, Choi JH, Gupta R, Safonova LP, Paunescu LA, Michalos A, Gratton E. Detection of the fast neuronal signal on the motor cortex using functional frequency domain near infrared spectroscopy. Adv Exp Med Biol. 2003; 510:193-7. PMID: 12580427.
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    299. Dong CY, French T, So PT, Buehler C, Berland KM, Gratton E. Fluorescence-lifetime imaging techniques for microscopy. Methods Cell Biol. 2003; 72:431-64. PMID: 14719344.
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    300. Wolf U, Wolf M, Choi JH, Paunescu LA, Safonova LP, Michalos A, Gratton E. Mapping of hemodynamics on the human calf with near infrared spectroscopy and the influence of the adipose tissue thickness. Adv Exp Med Biol. 2003; 510:225-30. PMID: 12580432.
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    301. Müller JD, Chen Y, Gratton E. Fluorescence correlation spectroscopy. Methods Enzymol. 2003; 361:69-92. PMID: 12624907.
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    302. Wolf M, Wolf U, Choi JH, Gupta R, Safonova LP, Paunescu LA, Michalos A, Gratton E. Functional frequency-domain near-infrared spectroscopy detects fast neuronal signal in the motor cortex. Neuroimage. 2002 Dec; 17(4):1868-75. PMID: 12498761.
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    303. Ruan Q, Chen Y, Gratton E, Glaser M, Mantulin WW. Cellular characterization of adenylate kinase and its isoform: two-photon excitation fluorescence imaging and fluorescence correlation spectroscopy. Biophys J. 2002 Dec; 83(6):3177-87. PMID: 12496087.
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    304. Best KB, Ohran AJ, Hawes AC, Hazlett TL, Gratton E, Judd AM, Bell JD. Relationship between erythrocyte membrane phase properties and susceptibility to secretory phospholipase A2. Biochemistry. 2002 Nov 26; 41(47):13982-8. PMID: 12437355.
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    305. Behne MJ, Meyer JW, Hanson KM, Barry NP, Murata S, Crumrine D, Clegg RW, Gratton E, Holleran WM, Elias PM, Mauro TM. NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging. J Biol Chem. 2002 Dec 06; 277(49):47399-406. PMID: 12221084.
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    306. Hanson KM, Behne MJ, Barry NP, Mauro TM, Gratton E, Clegg RM. Two-photon fluorescence lifetime imaging of the skin stratum corneum pH gradient. Biophys J. 2002 Sep; 83(3):1682-90. PMID: 12202391.
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    307. Wolf M, Wolf U, Toronov V, Michalos A, Paunescu LA, Choi JH, Gratton E. Different time evolution of oxyhemoglobin and deoxyhemoglobin concentration changes in the visual and motor cortices during functional stimulation: a near-infrared spectroscopy study. Neuroimage. 2002 Jul; 16(3 Pt 1):704-12. PMID: 12169254.
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    308. Fahsel S, Pospiech EM, Zein M, Hazlet TL, Gratton E, Winter R. Modulation of concentration fluctuations in phase-separated lipid membranes by polypeptide insertion. Biophys J. 2002 Jul; 83(1):334-44. PMID: 12080124.
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    309. Bettati S, Campanini B, Vaccari S, Mozzarelli A, Schianchi G, Hazlett TL, Gratton E, Benci S. Unfolding of pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase probed by time-resolved tryptophan fluorescence. Biochim Biophys Acta. 2002 Apr 01; 1596(1):47-54. PMID: 11983420.
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    310. Sanchez SA, Bagatolli LA, Gratton E, Hazlett TL. A two-photon view of an enzyme at work: Crotalus atrox venom PLA2 interaction with single-lipid and mixed-lipid giant unilamellar vesicles. Biophys J. 2002 Apr; 82(4):2232-43. PMID: 11916878.
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    311. Patel RC, Kumar U, Lamb DC, Eid JS, Rocheville M, Grant M, Rani A, Hazlett T, Patel SC, Gratton E, Patel YC. Ligand binding to somatostatin receptors induces receptor-specific oligomer formation in live cells. Proc Natl Acad Sci U S A. 2002 Mar 05; 99(5):3294-9. PMID: 11880655.
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    312. Tricerri MA, Sanchez SA, Arnulphi C, Durbin DM, Gratton E, Jonas A. Interaction of apolipoprotein A-I in three different conformations with palmitoyl oleoyl phosphatidylcholine vesicles. J Lipid Res. 2002 Feb; 43(2):187-97. PMID: 11861660.
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    313. Chen Y, Müller JD, Ruan Q, Gratton E. Molecular brightness characterization of EGFP in vivo by fluorescence fluctuation spectroscopy. Biophys J. 2002 Jan; 82(1 Pt 1):133-44. PMID: 11751302.
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    314. Bismuto E, Gratton E, Lamb DC. Dynamics of ANS binding to tuna apomyoglobin measured with fluorescence correlation spectroscopy. Biophys J. 2001 Dec; 81(6):3510-21. PMID: 11721012.
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    315. Toronov V, Webb A, Choi JH, Wolf M, Safonova L, Wolf U, Gratton E. Study of local cerebral hemodynamics by frequency-domain near-infrared spectroscopy and correlation with simultaneously acquired functional magnetic resonance imaging. Opt Express. 2001 Oct 08; 9(8):417-27. PMID: 19424359.
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    316. Gratton E, Barry NP, Beretta S, Celli A. Multiphoton fluorescence microscopy. Methods. 2001 Sep; 25(1):103-10. PMID: 11559001.
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    317. Sanchez SA, Chen Y, Müller JD, Gratton E, Hazlett TL. Solution and interface aggregation states of Crotalus atrox venom phospholipase A2 by two-photon excitation fluorescence correlation spectroscopy. Biochemistry. 2001 Jun 12; 40(23):6903-11. PMID: 11389605.
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    318. Krasnowska EK, Bagatolli LA, Gratton E, Parasassi T. Surface properties of cholesterol-containing membranes detected by Prodan fluorescence. Biochim Biophys Acta. 2001 Apr 02; 1511(2):330-40. PMID: 11286976.
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    319. Toronov V, Webb A, Choi JH, Wolf M, Michalos A, Gratton E, Hueber D. Investigation of human brain hemodynamics by simultaneous near-infrared spectroscopy and functional magnetic resonance imaging. Med Phys. 2001 Apr; 28(4):521-7. PMID: 11339749.
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    320. Chirico G, Bettati S, Mozzarelli A, Chen Y, Müller JD, Gratton E. Molecular heterogeneity of O-acetylserine sulfhydrylase by two-photon excited fluorescence fluctuation spectroscopy. Biophys J. 2001 Apr; 80(4):1973-85. PMID: 11259310.
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    321. Dong CY, Buehler C, So PT, French T, Gratton E. Implementation of intensity-modulated laser diodes in time-resolved, pump-probe fluorescence microscopy. Appl Opt. 2001 Mar 01; 40(7):1109-15. PMID: 18357095.
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    322. Van Rompaey E, Chen Y, Müller JD, Gratton E, Van Craenenbroeck E, Engelborghs Y, De Smedt S, Demeester J. Fluorescence fluctuation analysis for the study of interactions between oligonucleotides and polycationic polymers. Biol Chem. 2001 Mar; 382(3):379-86. PMID: 11347884.
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    323. Dietrich C, Bagatolli LA, Volovyk ZN, Thompson NL, Levi M, Jacobson K, Gratton E. Lipid rafts reconstituted in model membranes. Biophys J. 2001 Mar; 80(3):1417-28. PMID: 11222302.
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    324. Margeat E, Poujol N, Boulahtouf A, Chen Y, Müller JD, Gratton E, Cavailles V, Royer CA. The human estrogen receptor alpha dimer binds a single SRC-1 coactivator molecule with an affinity dictated by agonist structure. J Mol Biol. 2001 Feb 23; 306(3):433-42. PMID: 11178903.
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    325. Barcellona ML, Chen Y, Müller JD, Gratton E. 4',6-diamidino-2-phenylindole (DAPI) interacts with rare structures of GC polymers. Eur Biophys J. 2001; 30(2):98-109. PMID: 11409469.
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    326. Bettati S, Benci S, Campanini B, Raboni S, Chirico G, Beretta S, Schnackerz KD, Hazlett TL, Gratton E, Mozzarelli A. Role of pyridoxal 5'-phosphate in the structural stabilization of O-acetylserine sulfhydrylase. J Biol Chem. 2000 Dec 22; 275(51):40244-51. PMID: 10995767.
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    327. Chen Y, Müller JD, Tetin SY, Tyner JD, Gratton E. Probing ligand protein binding equilibria with fluorescence fluctuation spectroscopy. Biophys J. 2000 Aug; 79(2):1074-84. PMID: 10920037.
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    328. Bagatolli LA, Gratton E. A correlation between lipid domain shape and binary phospholipid mixture composition in free standing bilayers: A two-photon fluorescence microscopy study. Biophys J. 2000 Jul; 79(1):434-47. PMID: 10866969.
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    329. Buehler C, Dong CY, So PT, French T, Gratton E. Time-resolved polarization imaging by pump-probe (stimulated emission) fluorescence microscopy. Biophys J. 2000 Jul; 79(1):536-49. PMID: 10866979.
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    330. Zolese G, Falcioni G, Bertoli E, Galeazzi R, Wozniak M, Wypych Z, Gratton E, Ambrosini A. Steady-state and time resolved fluorescence of albumins interacting with N-oleylethanolamine, a component of the endogenous N-acylethanolamines. Proteins. 2000 Jul 01; 40(1):39-48. PMID: 10813829.
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    331. Bagatolli L, Gratton E, Khan TK, Chong PL. Two-photon fluorescence microscopy studies of bipolar tetraether giant liposomes from thermoacidophilic archaebacteria Sulfolobus acidocaldarius. Biophys J. 2000 Jul; 79(1):416-25. PMID: 10866967.
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    332. Casavola C, Paunescu LA, Fantini S, Gratton E. Blood flow and oxygen consumption with near-infrared spectroscopy and venous occlusion: spatial maps and the effect of time and pressure of inflation. J Biomed Opt. 2000 Jul; 5(3):269-76. PMID: 10958611.
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    333. Parasassi T, Yu W, Durbin D, Kuriashkina L, Gratton E, Maeda N, Ursini F. Two-photon microscopy of aorta fibers shows proteolysis induced by LDL hydroperoxides. Free Radic Biol Med. 2000 Jun 01; 28(11):1589-97. PMID: 10938454.
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    334. Frolov A, Petrescu A, Atshaves BP, So PT, Gratton E, Serrero G, Schroeder F. High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single- and multiphoton fluorescence approach. J Biol Chem. 2000 Apr 28; 275(17):12769-80. PMID: 10777574.
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    335. Bagatolli LA, Parasassi T, Gratton E. Giant phospholipid vesicles: comparison among the whole lipid sample characteristics using different preparation methods: a two photon fluorescence microscopy study. Chem Phys Lipids. 2000 Apr; 105(2):135-47. PMID: 10823462.
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    336. Toronov V, Franceschini MA, Filiaci M, Fantini S, Wolf M, Michalos A, Gratton E. Near-infrared study of fluctuations in cerebral hemodynamics during rest and motor stimulation: temporal analysis and spatial mapping. Med Phys. 2000 Apr; 27(4):801-15. PMID: 10798703.
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    337. Stankovic MR, Maulik D, Rosenfeld W, Stubblefield PG, Kofinas AD, Gratton E, Franceschini MA, Fantini S, Hueber DM. Role of frequency domain optical spectroscopy in the detection of neonatal brain hemorrhage--a newborn piglet study. J Matern Fetal Med. 2000 Mar-Apr; 9(2):142-9. PMID: 10902831.
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    338. Franceschini MA, Toronov V, Filiaci M, Gratton E, Fantini S. On-line optical imaging of the human brain with 160-ms temporal resolution. Opt Express. 2000 Jan 31; 6(3):49-57. PMID: 19401744.
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    339. Arcangeli C, Yu W, Cannistraro S, Gratton E. Two-photon autofluorescence microscopy and spectroscopy of Antarctic fungus: new approach for studying effects of UV-B irradiation. Biopolymers. 2000; 57(4):218-25. PMID: 10861386.
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    340. Müller JD, Chen Y, Gratton E. Resolving heterogeneity on the single molecular level with the photon-counting histogram. Biophys J. 2000 Jan; 78(1):474-86. PMID: 10620311.
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    341. Bagatolli LA, Gratton E. Two photon fluorescence microscopy of coexisting lipid domains in giant unilamellar vesicles of binary phospholipid mixtures. Biophys J. 2000 Jan; 78(1):290-305. PMID: 10620293.
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    342. Bagatolli LA, Gratton E. Two-photon fluorescence microscopy observation of shape changes at the phase transition in phospholipid giant unilamellar vesicles. Biophys J. 1999 Oct; 77(4):2090-101. PMID: 10512829.
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    343. Bagatolli LA, Parasassi T, Fidelio GD, Gratton E. A model for the interaction of 6-lauroyl-2-(N,N-dimethylamino)naphthalene with lipid environments: implications for spectral properties. Photochem Photobiol. 1999 Oct; 70(4):557-64. PMID: 10546552.
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    344. Chen Y, Müller JD, Berland KM, Gratton E. Fluorescence fluctuation spectroscopy. Methods. 1999 Oct; 19(2):234-52. PMID: 10527729.
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    345. Parasassi T, Gratton E, Zajicek H, Levi M, Yu W. Detecting membrane lipid microdomains by two-photon fluorescence microscopy. IEEE Eng Med Biol Mag. 1999 Sep-Oct; 18(5):92-9. PMID: 10497742.
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    346. Chen Y, Müller JD, So PT, Gratton E. The photon counting histogram in fluorescence fluctuation spectroscopy. Biophys J. 1999 Jul; 77(1):553-67. PMID: 10388780.
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    347. Franceschini MA, Gratton E, Fantini S. Noninvasive optical method of measuring tissue and arterial saturation: an application to absolute pulse oximetry of the brain. Opt Lett. 1999 Jun 15; 24(12):829-31. PMID: 18073868.
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    348. Fantini S, Hueber D, Franceschini MA, Gratton E, Rosenfeld W, Stubblefield PG, Maulik D, Stankovic MR. Non-invasive optical monitoring of the newborn piglet brain using continuous-wave and frequency-domain spectroscopy. Phys Med Biol. 1999 Jun; 44(6):1543-63. PMID: 10498522.
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    349. Fantini S, Franceschini M, Gratton E, Hueber D, Rosenfeld W, Maulik D, Stubblefield P, Stankovic M. Non-invasive optical mapping of the piglet brain in real time. Opt Express. 1999 Apr 12; 4(8):308-14. PMID: 19396287.
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    350. Stankovic MR, Maulik D, Rosenfeld W, Stubblefield PG, Kofinas AD, Drexler S, Nair R, Franceschini MA, Hueber D, Gratton E, Fantini S. Real-time optical imaging of experimental brain ischemia and hemorrhage in neonatal piglets. J Perinat Med. 1999; 27(4):279-86. PMID: 10560079.
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    351. Masters BR, So PT, Kim KH, Buehler C, Gratton E. Multiphoton excitation microscopy, confocal microscopy, and spectroscopy of living cells and tissues; functional metabolic imaging of human skin in vivo. Methods Enzymol. 1999; 307:513-36. PMID: 10506992.
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    352. Casavola C, Paunescu LA, Fantini S, Franceschini MA, Lugarà PM, Gratton E. Application of near-infrared tissue oxymetry to the diagnosis of peripheral vascular disease. Clin Hemorheol Microcirc. 1999; 21(3-4):389-93. PMID: 10711775.
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    353. Lasagna M, Gratton E, Jameson DM, Brunet JE. Apohorseradish peroxidase unfolding and refolding: intrinsic tryptophan fluorescence studies. Biophys J. 1999 Jan; 76(1 Pt 1):443-50. PMID: 9876156.
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    354. Franceschini MA, Fantini S, Paunescu LA, Maier JS, Gratton E. Influence of a superficial layer in the quantitative spectroscopic study of strongly scattering media. Appl Opt. 1998 Nov 01; 37(31):7447-58. PMID: 18301579.
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    355. Di Venere A, Mei G, Gilardi G, Rosato N, De Matteis F, McKay R, Gratton E, Finazzi Agrò A. Resolution of the heterogeneous fluorescence in multi-tryptophan proteins: ascorbate oxidase. Eur J Biochem. 1998 Oct 15; 257(2):337-43. PMID: 9826178.
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    356. Bagatolli LA, Gratton E, Fidelio GD. Water dynamics in glycosphingolipid aggregates studied by LAURDAN fluorescence. Biophys J. 1998 Jul; 75(1):331-41. PMID: 9649390.
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    357. So PT, König K, Berland K, Dong CY, French T, Bühler C, Ragan T, Gratton E. New time-resolved techniques in two-photon microscopy. Cell Mol Biol (Noisy-le-grand). 1998 Jul; 44(5):771-93. PMID: 9764747.
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    358. Krasnowska EK, Gratton E, Parasassi T. Prodan as a membrane surface fluorescence probe: partitioning between water and phospholipid phases. Biophys J. 1998 Apr; 74(4):1984-93. PMID: 9545057.
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    359. Walker SA, Boas DA, Gratton E. Photon density waves scattered from cylindrical inhomogeneities: theory and experiments. Appl Opt. 1998 Apr 01; 37(10):1935-44. PMID: 18273113.
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    360. Masters BR, So PT, Gratton E. Multiphoton excitation microscopy of in vivo human skin. Functional and morphological optical biopsy based on three-dimensional imaging, lifetime measurements and fluorescence spectroscopy. Ann N Y Acad Sci. 1998 Feb 09; 838:58-67. PMID: 9511795.
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    361. French T, So PT, Dong CY, Berland KM, Gratton E. Fluorescence lifetime imaging techniques for microscopy. Methods Cell Biol. 1998; 56:277-304. PMID: 9500143.
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    362. Gratton G, Fabiani M, Corballis PM, Hood DC, Goodman-Wood MR, Hirsch J, Kim K, Friedman D, Gratton E. Fast and localized event-related optical signals (EROS) in the human occipital cortex: comparisons with the visual evoked potential and fMRI. Neuroimage. 1997 Oct; 6(3):168-80. PMID: 9344821.
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    363. Gratton E, Fantini S, Franceschini MA, Gratton G, Fabiani M. Measurements of scattering and absorption changes in muscle and brain. Philos Trans R Soc Lond B Biol Sci. 1997 Jun 29; 352(1354):727-35. PMID: 9232861.
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    364. Franceschini MA, Moesta KT, Fantini S, Gaida G, Gratton E, Jess H, Mantulin WW, Seeber M, Schlag PM, Kaschke M. Frequency-domain techniques enhance optical mammography: initial clinical results. Proc Natl Acad Sci U S A. 1997 Jun 10; 94(12):6468-73. PMID: 9177241.
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    365. Masters BR, So PT, Gratton E. Multiphoton excitation fluorescence microscopy and spectroscopy of in vivo human skin. Biophys J. 1997 Jun; 72(6):2405-12. PMID: 9168018.
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    366. Parasassi T, Gratton E, Yu WM, Wilson P, Levi M. Two-photon fluorescence microscopy of laurdan generalized polarization domains in model and natural membranes. Biophys J. 1997 Jun; 72(6):2413-29. PMID: 9168019.
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    367. Gratton G, Fabiani M, Corballis PM, Gratton E. Noninvasive detection of fast signals from the cortex using frequency-domain optical methods. Ann N Y Acad Sci. 1997 May 30; 820:286-98; discussion 298-9. PMID: 9237461.
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    368. Franceschini MA, Fantini S, Cerussi AE, Barbieri BB, Chance B, Gratton E. Quantitative spectroscopic determination of hemoglobin concentration and saturation in a turbid medium: analysis of the effect of water absorption. J Biomed Opt. 1997 Apr; 2(2):147-53. PMID: 23014867.
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    369. French T, So PT, Weaver DJ, Coelho-Sampaio T, Gratton E, Voss EW, Carrero J. Two-photon fluorescence lifetime imaging microscopy of macrophage-mediated antigen processing. J Microsc. 1997 Mar; 185(Pt 3):339-53. PMID: 9134740.
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    370. Bernsdorff C, Wolf A, Winter R, Gratton E. Effect of hydrostatic pressure on water penetration and rotational dynamics in phospholipid-cholesterol bilayers. Biophys J. 1997 Mar; 72(3):1264-77. PMID: 9138572.
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    371. König K, So PT, Mantulin WW, Gratton E. Cellular response to near-infrared femtosecond laser pulses in two-photon microscopes. Opt Lett. 1997 Jan 15; 22(2):135-6. PMID: 18183127.
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    372. Fantini S, Franceschini MA, Gratton E. Effective source term in the diffusion equation for photon transport in turbid media. Appl Opt. 1997 Jan 01; 36(1):156-63. PMID: 18250657.
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    373. Walker SA, Fantini S, Gratton E. Image reconstruction by backprojection from frequency-domain optical measurements in highly scattering media. Appl Opt. 1997 Jan 01; 36(1):170-4. PMID: 18250659.
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    374. Cerussi AE, Maier JS, Fantini S, Franceschini MA, Mantulin WW, Gratton E. Experimental verification of a theory for the time-resolved fluorescence spectroscopy of thick tissues. Appl Opt. 1997 Jan 01; 36(1):116-24. PMID: 18250652.
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    375. Barshtein G, Bergelson L, Dagan A, Gratton E, Yedgar S. Membrane lipid order of human red blood cells is altered by physiological levels of hydrostatic pressure. Am J Physiol. 1997 Jan; 272(1 Pt 2):H538-43. PMID: 9038976.
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    376. Zolese G, Giambanco I, Curatola G, Staffolani R, Gratton E, Donato R. Time-resolved fluorescence of S-100a protein: effect of Ca2+, Mg2+ and unilamellar vesicles of egg phosphatidylcholine. Cell Calcium. 1996 Dec; 20(6):465-74. PMID: 8985591.
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    377. König K, So PT, Mantulin WW, Tromberg BJ, Gratton E. Two-photon excited lifetime imaging of autofluorescence in cells during UVA and NIR photostress. J Microsc. 1996 Sep; 183(Pt 3):197-204. PMID: 8858857.
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    378. Berland KM, So PT, Chen Y, Mantulin WW, Gratton E. Scanning two-photon fluctuation correlation spectroscopy: particle counting measurements for detection of molecular aggregation. Biophys J. 1996 Jul; 71(1):410-20. PMID: 8804624.
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    379. Barcellona ML, Gratton E. Fluorescence anisotropy of DNA/DAPI complex: torsional dynamics and geometry of the complex. Biophys J. 1996 May; 70(5):2341-51. PMID: 9172758.
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    380. Parasassi T, Gratton E. Comments on 1,6-diphenyl-1,3,5-hexatriene fluorescence decrease at critical cholesterol concentration in phospholipid membranes. Biophys J. 1996 Mar; 70(3):1560-2. PMID: 8785314.
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    381. Yu W, So PT, French T, Gratton E. Fluorescence generalized polarization of cell membranes: a two-photon scanning microscopy approach. Biophys J. 1996 Feb; 70(2):626-36. PMID: 8789081.
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    382. Bismuto E, Sirangelo I, Irace G, Gratton E. Pressure-induced perturbation of apomyoglobin structure: fluorescence studies on native and acidic compact forms. Biochemistry. 1996 Jan 30; 35(4):1173-8. PMID: 8573571.
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    383. Barcellona ML, Gratton E. Torsional dynamics and orientation of DNA--DAPI complexes. Biochemistry. 1996 Jan 09; 35(1):321-33. PMID: 8555192.
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    384. Fantini S, Franceschini MA, Gaida G, Gratton E, Jess H, Mantulin WW, Moesta KT, Schlag PM, Kaschke M. Frequency-domain optical mammography: edge effect corrections. Med Phys. 1996 Jan; 23(1):149-57. PMID: 8700026.
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    385. Barshtein G, Bergelson L, Gratton E, Yedgar S. Human red blood cell shape and volume are changed by physiological levels of hydrostatic pressure. J Basic Clin Physiol Pharmacol. 1996; 7(4):321-9. PMID: 9080306.
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    386. Bismuto E, Irace G, Sirangelo I, Gratton E. Pressure-induced perturbation of ANS-apomyoglobin complex: frequency domain fluorescence studies on native and acidic compact states. Protein Sci. 1996 Jan; 5(1):121-6. PMID: 8771204.
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    387. Dong CY, So PT, French T, Gratton E. Fluorescence lifetime imaging by asynchronous pump-probe microscopy. Biophys J. 1995 Dec; 69(6):2234-42. PMID: 8599631.
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    388. Parasassi T, Giusti AM, Raimondi M, Ravagnan G, Sapora O, Gratton E. Cholesterol protects the phospholipid bilayer from oxidative damage. Free Radic Biol Med. 1995 Oct; 19(4):511-6. PMID: 7590402.
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    389. Parasassi T, Giusti AM, Raimondi M, Gratton E. Abrupt modifications of phospholipid bilayer properties at critical cholesterol concentrations. Biophys J. 1995 May; 68(5):1895-902. PMID: 7612832.
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    390. Carrero J, Jameson DM, Gratton E. Oxygen penetration and diffusion into myoglobin revealed by quenching of zincprotoporphyrin IX fluorescence. Biophys Chem. 1995 Apr; 54(2):143-54. PMID: 7756566.
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    391. De Blasi RA, Fantini S, Franceschini MA, Ferrari M, Gratton E. Cerebral and muscle oxygen saturation measurement by frequency-domain near-infra-red spectrometer. Med Biol Eng Comput. 1995 Mar; 33(2):228-30. PMID: 7643667.
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    392. Fishkin JB, So PT, Cerussi AE, Fantini S, Franceschini MA, Gratton E. Frequency-domain method for measuring spectral properties in multiple-scattering media: methemoglobin absorption spectrum in a tissuelike phantom. Appl Opt. 1995 Mar 01; 34(7):1143-55. PMID: 21037643.
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    393. Parasassi T, Gratton E. Membrane lipid domains and dynamics as detected by Laurdan fluorescence. J Fluoresc. 1995 Mar; 5(1):59-69. PMID: 24226612.
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    394. Gratton E, Parasassi T. Fluorescence lifetime distributions in membrane systems. J Fluoresc. 1995 Mar; 5(1):51-7. PMID: 24226611.
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    395. Berland KM, So PT, Gratton E. Two-photon fluorescence correlation spectroscopy: method and application to the intracellular environment. Biophys J. 1995 Feb; 68(2):694-701. PMID: 7696520.
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    396. Gratton G, Fabiani M, Friedman D, Franceschini MA, Fantini S, Corballis P, Gratton E. Rapid changes of optical parameters in the human brain during a tapping task. J Cogn Neurosci. 1995; 7(4):446-56. PMID: 23961904.
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    397. Maier JS, Walker SA, Fantini S, Franceschini MA, Gratton E. Possible correlation between blood glucose concentration and the reduced scattering coefficient of tissues in the near infrared. Opt Lett. 1994 Dec 15; 19(24):2062-4. PMID: 19855740.
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    398. Fantini S, Franceschini MA, Fishkin JB, Barbieri B, Gratton E. Quantitative determination of the absorption spectra of chromophores in strongly scattering media: a light-emitting-diode based technique. Appl Opt. 1994 Aug 01; 33(22):5204-13. PMID: 20935909.
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    399. Ferreira ST, Stella L, Gratton E. Conformational dynamics of bovine Cu, Zn superoxide dismutase revealed by time-resolved fluorescence spectroscopy of the single tyrosine residue. Biophys J. 1994 Apr; 66(4):1185-96. PMID: 8038390.
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    400. Parasassi T, Giusti AM, Gratton E, Monaco E, Raimondi M, Ravagnan G, Sapora O. Evidence for an increase in water concentration in bilayers after oxidative damage of phospholipids induced by ionizing radiation. Int J Radiat Biol. 1994 Mar; 65(3):329-34. PMID: 7908312.
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    401. Gratton G, Maier JS, Fabiani M, Mantulin WW, Gratton E. Feasibility of intracranial near-infrared optical scanning. Psychophysiology. 1994 Mar; 31(2):211-5. PMID: 8153259.
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    402. Parasassi T, Di Stefano M, Loiero M, Ravagnan G, Gratton E. Cholesterol modifies water concentration and dynamics in phospholipid bilayers: a fluorescence study using Laurdan probe. Biophys J. 1994 Mar; 66(3 Pt 1):763-8. PMID: 8011908.
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    403. Brunet JE, Vargas V, Gratton E, Jameson DM. Hydrodynamics of horseradish peroxidase revealed by global analysis of multiple fluorescence probes. Biophys J. 1994 Feb; 66(2 Pt 1):446-53. PMID: 8161698.
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    404. Kantar A, Giorgi PL, Gratton E, Fiorini R. Probing the Interaction of PAF with Human Platelet Membrane Using the Fluorescent Probe Laurdan. Platelets. 1994; 5(3):145-8. PMID: 21043628.
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    405. Parasassi T, Di Stefano M, Loiero M, Ravagnan G, Gratton E. Influence of cholesterol on phospholipid bilayers phase domains as detected by Laurdan fluorescence. Biophys J. 1994 Jan; 66(1):120-32. PMID: 8130331.
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    406. Parasassi T, Loiero M, Raimondi M, Ravagnan G, Gratton E. Absence of lipid gel-phase domains in seven mammalian cell lines and in four primary cell types. Biochim Biophys Acta. 1993 Dec 12; 1153(2):143-54. PMID: 8274484.
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    407. Silva N, Gratton E, Mei G, Rosato N, Rusch R, Finazzi-Agrò A. Molten globule monomers in human superoxide dismutase. Biophys Chem. 1993 Dec; 48(2):171-82. PMID: 8298055.
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    408. Bismuto E, Gratton E, Sirangelo I, Irace G. Structure and dynamics of the acidic compact state of apomyoglobin by frequency-domain fluorometry. Eur J Biochem. 1993 Nov 15; 218(1):213-9. PMID: 8243466.
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    409. Van de Ven M, Cao J, Royer C, Gratton E. Multifrequency cross-correlation phase fluorometry of chlorophyll a fluorescence in thylakoid and PSII-enriched membranes. Photochem Photobiol. 1993 Sep; 58(3):438-45. PMID: 8234479.
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    410. Zolese G, Staffolani R, Mazzanti L, Gratton E. Effect of divalent cations on Na+,K(+)-ATPase obtained from human placenta. FEBS Lett. 1993 May 24; 323(1-2):11-4. PMID: 8388334.
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    411. van der Meer BW, Raymer MA, Wagoner SL, Hackney RL, Beechem JM, Gratton E. Designing matrix models for fluorescence energy transfer between moving donors and acceptors. Biophys J. 1993 Apr; 64(4):1243-63. PMID: 8494980.
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    412. Parasassi T, Ravagnan G, Rusch RM, Gratton E. Modulation and dynamics of phase properties in phospholipid mixtures detected by Laurdan fluorescence. Photochem Photobiol. 1993 Mar; 57(3):403-10. PMID: 8475171.
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    413. Levi M, Wilson PV, Cooper OJ, Gratton E. Lipid phases in renal brush border membranes revealed by Laurdan fluorescence. Photochem Photobiol. 1993 Mar; 57(3):420-5. PMID: 8475174.
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    414. Fiorini R, Curatola G, Kantar A, Giorgi PL, Gratton E. Use of Laurdan fluorescence in studying plasma membrane organization of polymorphonuclear leukocytes during the respiratory burst. Photochem Photobiol. 1993 Mar; 57(3):438-41. PMID: 8475176.
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    415. Fishkin JB, Gratton E. Propagation of photon-density waves in strongly scattering media containing an absorbing semi-infinite plane bounded by a straight edge. J Opt Soc Am A. 1993 Jan; 10(1):127-40. PMID: 8478741.
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    416. Parasassi T, Di Stefano M, Ravagnan G, Sapora O, Gratton E. Membrane aging during cell growth ascertained by Laurdan generalized polarization. Exp Cell Res. 1992 Oct; 202(2):432-9. PMID: 1397095.
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    417. Parasassi T, Gratton E. Packing of phospholipid vesicles studied by oxygen quenching of Laurdan fluorescence. J Fluoresc. 1992 Sep; 2(3):167-74. PMID: 24241627.
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    418. Mei G, Rosato N, Silva N, Rusch R, Gratton E, Savini I, Finazzi-Agrò A. Denaturation of human Cu/Zn superoxide dismutase by guanidine hydrochloride: a dynamic fluorescence study. Biochemistry. 1992 Aug 18; 31(32):7224-30. PMID: 1510915.
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    419. Parasassi T, Ravagnan G, Sapora O, Gratton E. Membrane oxidative damage induced by ionizing radiation detected by diphenylhexatriene fluorescence lifetime distributions. Int J Radiat Biol. 1992 Jun; 61(6):791-6. PMID: 1351529.
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    420. Reinhart GD, Marzola P, Jameson DM, Gratton E. A method for on-line background subtraction in frequency domain fluorometry. J Fluoresc. 1991 Sep; 1(3):153-62. PMID: 24242993.
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    421. Parasassi T, De Stasio G, Ravagnan G, Rusch RM, Gratton E. Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence. Biophys J. 1991 Jul; 60(1):179-89. PMID: 1883937.
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    422. Barcellona ML, Gratton E. A molecular approach to 4',6-diamidine-2-phenylindole (DAPI) photophysical behaviour at different pH values. Biophys Chem. 1991 Jul; 40(3):223-9. PMID: 1655085.
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    423. Wang S, Beechem JM, Gratton E, Glaser M. Orientational distribution of 1,6-diphenyl-1,3,5-hexatriene in phospholipid vesicles as determined by global analysis of frequency domain fluorimetry data. Biochemistry. 1991 Jun 04; 30(22):5565-72. PMID: 2036426.
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    424. Arduini A, vande Ven MJ, Shohet SB, Mancinelli G, Gratton E. Measurement and analysis of triplet-state lifetimes by multifrequency cross-correlation phase and modulation phosphorimetry. Anal Biochem. 1991 Jun; 195(2):327-9. PMID: 1750688.
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    425. Di Iorio EE, Hiltpold UR, Filipovic D, Winterhalter KH, Gratton E, Vitrano E, Cupane A, Leone M, Cordone L. Protein dynamics. Comparative investigation on heme-proteins with different physiological roles. Biophys J. 1991 Mar; 59(3):742-54. PMID: 2049528.
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    426. Axelsen PH, Gratton E, Prendergast FG. Experimentally verifying molecular dynamics simulations through fluorescence anisotropy measurements. Biochemistry. 1991 Feb 05; 30(5):1173-9. PMID: 1991096.
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    427. Parasassi T, De Stasio G, Rusch RM, Gratton E. A photophysical model for diphenylhexatriene fluorescence decay in solvents and in phospholipid vesicles. Biophys J. 1991 Feb; 59(2):466-75. PMID: 2009361.
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    428. Pin S, Royer CA, Gratton E, Alpert B, Weber G. Subunit interactions in hemoglobin probed by fluorescence and high-pressure techniques. Biochemistry. 1990 Oct 02; 29(39):9194-202. PMID: 2271588.
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    429. Rosato N, Gratton E, Mei G, Finazzi-Agrò A. Fluorescence lifetime distributions in human superoxide dismutase. Effect of temperature and denaturation. Biophys J. 1990 Oct; 58(4):817-22. PMID: 2248991.
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    430. Barcellona ML, Cardiel G, Gratton E. Time-resolved fluorescence of DAPI in solution and bound to polydeoxynucleotides. Biochem Biophys Res Commun. 1990 Jul 16; 170(1):270-80. PMID: 2372293.
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    431. VanderMeulen DL, Nealon DG, Gratton E, Jameson DM. Excitation wavelength dependent fluorescence anisotropy of eosin-myosin adducts. Evidence for anisotropic rotations. Biophys Chem. 1990 Jul; 36(2):177-84. PMID: 1698474.
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    432. Zolese G, Gratton E, Curatola G. Phosphatidic acid affects structural organization of phosphatidylcholine liposomes. A study of 1,6-diphenyl-1,3,5-hexatriene (DPH) and 1-(4-trimethylammonium-phenyl)-6-phenyl-1,3,5-hexatriene (TMA-DPH) fluorescence decay using distributional analysis. Chem Phys Lipids. 1990 Jul; 55(1):29-39. PMID: 2208443.
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    433. Parasassi T, De Stasio G, d'Ubaldo A, Gratton E. Phase fluctuation in phospholipid membranes revealed by Laurdan fluorescence. Biophys J. 1990 Jun; 57(6):1179-86. PMID: 2393703.
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    434. Rosato N, Mei G, Gratton E, Bannister JV, Bannister WH, Finazzi-Agrò A. A time-resolved fluorescence study of human copper-zinc superoxide dismutase. Biophys Chem. 1990 May; 36(1):41-6. PMID: 2207272.
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    435. Barcellona ML, Cardiel G, Gratton E. DAPI fluorescence decay process: a global analytical approach proves a ground-state heterogeneity with interconversion. Ital J Biochem. 1990 May-Jun; 39(3):179A-181A. PMID: 2391226.
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    436. van de Ven M, Preston C, Seibert M, Gratton E. Chlorophyll a fluorescence lifetime distributions in open and closed photosystem II reaction center preparations. Biochim Biophys Acta. 1990 Feb 02; 1015(2):173-9. PMID: 2404517.
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    437. Parasassi T, De Stasio G, Miccheli A, Bruno F, Conti F, Gratton E. Abscisic acid-induced microheterogeneity in phospholipid vesicles. A fluorescence study. Biophys Chem. 1990 Jan; 35(1):65-73. PMID: 2139348.
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    438. Rosato N, Gratton E, Mei G, Savini I, Finazzi Agrò A. Dynamic fluorescence in copper proteins. Selected examples. Biol Met. 1990; 3(2):133-6. PMID: 2096899.
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    439. Barcellona ML, Gratton E. The fluorescence properties of a DNA probe. 4'-6-Diamidino-2-phenylindole (DAPI). Eur Biophys J. 1990; 17(6):315-23. PMID: 2307139.
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    440. Parasassi T, Stasio GD, Miccheli A, Bruno F, Conti F, Gratton E. Abscisic acid-induced microheterogeneity in phospholipid vesicle: a fluorescence study. Biophys Chem. 1990 Jan; 35(1):65-73. PMID: 17056422.
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    441. Barcellona ML, Gratton E. Fluorescence lifetime distributions of DNA-4',6-diamidino-2-phenylindole complex. Biochim Biophys Acta. 1989 Dec 08; 993(2-3):174-8. PMID: 2597690.
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    442. Piston DW, Gratton E. Orientational exchange approach to fluorescence anisotropy decay. Biophys J. 1989 Dec; 56(6):1083-91. PMID: 2611325.
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    443. Fiorini R, Gratton E, Curatola G. Effect of cholesterol on membrane microheterogeneity: a study using 1,6-diphenyl-1,3,5-hexatriene fluorescence lifetime distributions. Biochim Biophys Acta. 1989 Nov 28; 1006(2):198-202. PMID: 2597667.
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    444. Wratten ML, Gratton E, van de Ven M, Sevanian A. DPH lifetime distributions in vesicles containing phospholipid hydroperoxides. Biochem Biophys Res Commun. 1989 Oct 16; 164(1):169-75. PMID: 2803293.
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    445. Bismuto E, Irace G, Gratton E. Multiple conformational states in myoglobin revealed by frequency domain fluorometry. Biochemistry. 1989 Feb 21; 28(4):1508-12. PMID: 2719914.
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    446. Schroeder F, Nemecz G, Gratton E, Barenholz Y, Thompson TE. Fluorescence properties of cholestatrienol in phosphatidylcholine bilayer vesicles. Biophys Chem. 1988 Oct; 32(1):57-72. PMID: 3233314.
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    447. Valentino M, Governa M, Gratton E, Fiorini R, Curatola G, Bertoli E. Increased membrane heterogeneity in stimulated human granulocytes. FEBS Lett. 1988 Jul 18; 234(2):451-4. PMID: 3391284.
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    448. Fiorini RM, Valentino M, Glaser M, Gratton E, Curatola G. Fluorescence lifetime distributions of 1,6-diphenyl-1,3,5-hexatriene reveal the effect of cholesterol on the microheterogeneity of erythrocyte membrane. Biochim Biophys Acta. 1988 Apr 22; 939(3):485-92. PMID: 3355828.
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    449. Thompson RB, Gratton E. Phase fluorometric method for determination of standard lifetimes. Anal Chem. 1988 Apr 01; 60(7):670-4. PMID: 3382018.
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    450. Bismuto E, Gratton E, Irace G. Effect of unfolding on the tryptophanyl fluorescence lifetime distribution in apomyoglobin. Biochemistry. 1988 Mar 22; 27(6):2132-6. PMID: 3378049.
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    451. Rosato N, Finazzi-Agro A, Gratton E, Stefanini S, Chiancone E. Time-resolved fluorescence of apoferritin and its subunits. J Biol Chem. 1987 Oct 25; 262(30):14487-91. PMID: 3667586.
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    452. Fiorini RM, Valentino M, Gratton E, Bertoli E, Curatola G. Erythrocyte membrane heterogeneity studied using 1,6-diphenyl-1,3,5-hexatriene fluorescence lifetime distribution. Biochem Biophys Res Commun. 1987 Aug 31; 147(1):460-6. PMID: 3632679.
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    453. Fiorini R, Valentino M, Wang S, Glaser M, Gratton E. Fluorescence lifetime distributions of 1,6-diphenyl-1,3,5-hexatriene in phospholipid vesicles. Biochemistry. 1987 Jun 30; 26(13):3864-70. PMID: 3651418.
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    454. Jameson DM, Gratton E, Eccleston JF. Intrinsic fluorescence of elongation factor Tu in its complexes with GDP and elongation factor Ts. Biochemistry. 1987 Jun 30; 26(13):3894-901. PMID: 3651421.
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    455. Eccleston JF, Gratton E, Jameson DM. Interaction of a fluorescent analogue of GDP with elongation factor Tu: steady-state and time-resolved fluorescence studies. Biochemistry. 1987 Jun 30; 26(13):3902-7. PMID: 3651422.
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    456. Bismuto E, Irace G, Colonna G, Jameson DM, Gratton E. Dynamic aspects of the heme-binding site in phylogenetically distant myoglobins. Biochim Biophys Acta. 1987 Jun 17; 913(2):150-4. PMID: 3593736.
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    457. Alcala JR, Gratton E, Prendergast FG. Interpretation of fluorescence decays in proteins using continuous lifetime distributions. Biophys J. 1987 Jun; 51(6):925-36. PMID: 3607213.
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    458. Schroeder F, Barenholz Y, Gratton E, Thompson TE. A fluorescence study of dehydroergosterol in phosphatidylcholine bilayer vesicles. Biochemistry. 1987 May 05; 26(9):2441-8. PMID: 3607026.
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    459. Parasassi T, Conti F, Gratton E, Sapora O. Membranes modification of differentiating proerythroblasts. Variation of 1,6-diphenyl-1,3,5-hexatriene lifetime distributions by multifrequency phase and modulation fluorimetry. Biochim Biophys Acta. 1987 Apr 09; 898(2):196-201. PMID: 3828340.
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    460. Alcala JR, Gratton E, Prendergast FG. Fluorescence lifetime distributions in proteins. Biophys J. 1987 Apr; 51(4):597-604. PMID: 3580486.
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    461. Alcala JR, Gratton E, Prendergast FG. Resolvability of fluorescence lifetime distributions using phase fluorometry. Biophys J. 1987 Apr; 51(4):587-96. PMID: 3580485.
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    462. Gratton E, Alcala JR, Marriott G. Rotations of tryptophan residues in proteins. Biochem Soc Trans. 1986 Oct; 14(5):835-8. PMID: 3781081.
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    463. Parasassi T, Conti F, Gratton E. Fluorophores in a polar medium: time dependence of emission spectra detected by multifrequency phase and modulation fluorometry. Cell Mol Biol. 1986; 32(1):99-102. PMID: 3948209.
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    464. Parasassi T, Conti F, Gratton E. Time-resolved fluorescence emission spectra of Laurdan in phospholipid vesicles by multifrequency phase and modulation fluorometry. Cell Mol Biol. 1986; 32(1):103-8. PMID: 3753899.
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    465. Frauenfelder H, Gratton E. Protein dynamics and hydration. Methods Enzymol. 1986; 127:207-16. PMID: 3016460.
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    466. Parasassi T, Conti F, Glaser M, Gratton E. Detection of phospholipid phase separation. A multifrequency phase fluorimetry study of 1,6-diphenyl-1,3,5-hexatriene fluorescence. J Biol Chem. 1984 Nov 25; 259(22):14011-7. PMID: 6548746.
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    467. Marque J, Eisenstein L, Gratton E, Sturtevant JM, Hardy CJ. Thermodynamic properties of purple membrane. Biophys J. 1984 Nov; 46(5):567-72. PMID: 6498271.
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    468. Gratton E, Limkeman M, Lakowicz JR, Maliwal BP, Cherek H, Laczko G. Resolution of mixtures of fluorophores using variable-frequency phase and modulation data. Biophys J. 1984 Oct; 46(4):479-86. PMID: 6498265.
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    469. Lakowicz JR, Laczko G, Cherek H, Gratton E, Limkeman M. Analysis of fluorescence decay kinetics from variable-frequency phase shift and modulation data. Biophys J. 1984 Oct; 46(4):463-77. PMID: 6498264.
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    470. Conti F, Parasassi T, Rosato N, Sapora O, Gratton E. Fluorescence studies using synchrotron radiation on normal and differentiated cells labeled with parinaric acids. Biochim Biophys Acta. 1984 Sep 14; 805(1):117-22. PMID: 6591957.
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    471. Lakowicz JR, Gratton E, Cherek H, Maliwal BP, Laczko G. Determination of time-resolved fluorescence emission spectra and anisotropies of a fluorophore-protein complex using frequency-domain phase-modulation fluorometry. J Biol Chem. 1984 Sep 10; 259(17):10967-72. PMID: 6469993.
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    472. Gratton E, Jameson DM, Weber G, Alpert B. A model of dynamic quenching of fluorescence in globular proteins. Biophys J. 1984 Apr; 45(4):789-94. PMID: 6722266.
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    473. Jameson DM, Gratton E, Weber G, Alpert B. Oxygen distribution and migration within Mbdes Fe and Hbdes Fe. Multifrequency phase and modulation fluorometry study. Biophys J. 1984 Apr; 45(4):795-803. PMID: 6722267.
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    474. Gratton E, Jameson DM, Hall RD. Multifrequency phase and modulation fluorometry. Annu Rev Biophys Bioeng. 1984; 13:105-24. PMID: 6378065.
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    475. Gratton E, Limkeman M. A continuously variable frequency cross-correlation phase fluorometer with picosecond resolution. Biophys J. 1983 Dec; 44(3):315-24. PMID: 6661490.
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    476. Gavish B, Gratton E, Hardy CJ. Adiabatic compressibility of globular proteins. Proc Natl Acad Sci U S A. 1983 Feb; 80(3):750-4. PMID: 6572366.
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    477. Careri G, Gratton E, Yang PH, Rupley JA. Correlation of IR spectroscopic, heat capacity, diamagnetic susceptibility and enzymatic measurements on lysozyme powder. Nature. 1980 Apr 10; 284(5756):572-3. PMID: 7366728.
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    478. Frontali C, Dore E, Ferrauto A, Gratton E, Bettini A, Pozzan MR, Valdevit E. An absolute method for the determination of the persistence length of native DNA from electron micrographs. Biopolymers. 1979 Jun; 18(6):1353-73. PMID: 465647.
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    479. Gratton E, Delgado RL. Use of synchrotron radiation for the measurement of fluorescence lifetimes with subpicosecond resolution. Rev Sci Instrum. 1979 Jun; 50(6):789. PMID: 18699606.
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    480. Careri G, Giansanti A, Gratton E. Lysozyme film hydration events: an ir and gravimetric study. Biopolymers. 1979 May; 18(5):1187-203. PMID: 435612.
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    481. Careri G, Fasella P, Gratton E. Enzyme dynamics: the statistical physics approach. Annu Rev Biophys Bioeng. 1979; 8:69-97. PMID: 383008.
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    482. Ascoli F, Gratton E, Riva F, Fasella P, Brunori M. Infrared stretching frequencies of CO in carbomonoxyhemoglobin from trout. Biochim Biophys Acta. 1978 Apr 26; 533(2):534-7. PMID: 647025.
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    483. Careri G, Gratton E. Onsager coupling in enzymes. Biosystems. 1977 Apr; 8(4):185-6. PMID: 884214.
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    484. Careri G, Fasella P, Gratton E. Statistical time events in enzymes: a physical assessment. CRC Crit Rev Biochem. 1975 Aug; 3(2):141-64. PMID: 1100316.
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    485. Dore E, Frontali C, Gratton E. Physico-chemical description of a condensed form of DNA. Biopolymers. 1972 Feb; 11(2):443-59. PMID: 4552677.
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    486. Dore E, Frontali C, Gratton E. The role of ions in the acid melting of DNA. Biopolymers. 1972; 11(10):2033-41. PMID: 5078386.
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    487. Gratton E. Method for the automatic correction of scattering in absorption spectra by using the integrating sphere. Biopolymers. 1971; 10(12):2629-34. PMID: 5126535.
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