Craig Walsh

Title(s)Professor, Molecular Biology & Biochemistry
SchoolSchool of Biological Sciences
Address3215 McGaugh Hall
Zot 3900
Irvine CA 92697
Phone(949) 824-8487, 9343
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    Collapse Research 
    Collapse Research Activities and Funding
    Hyperion multi-parameter high-dimensional imaging mass cytometry platform
    NIH S10OD028645Apr 15, 2021 - Apr 14, 2022
    Role: Principal Investigator
    Regulation of T cell metabolism by DRAK2
    NIH R21AI144823Feb 1, 2019 - Jan 31, 2021
    Role: Principal Investigator
    Endogenous human antibodies in aging and Alzheimer's disease and the immune response to amyloid
    NIH RF1AG061857Sep 30, 2018 - Mar 31, 2023
    Role: Co-Principal Investigator
    Modulation of T Cell Activation and Tolerance by DRAK2
    NIH R01AI063419Jun 1, 2005 - Nov 28, 2011
    Role: Principal Investigator
    Growth Regulation of Activated T Cells by FADD
    NIH R01AI050606Dec 1, 2002 - Nov 30, 2008
    Role: Principal Investigator
    DEATH RECEPTOR SIGNALING PATHWAYS IN T CELL DEVELOPMENT
    NIH F32AI010454Apr 1, 2000
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Graft conditioning with fluticasone propionate reduces graft-versus-host disease upon allogeneic hematopoietic cell transplantation in mice. EMBO Mol Med. 2023 09 11; 15(9):e17748. Varady ES, Ayala LA, Nguyen PU, Scarfone VM, Karimzadeh A, Zhou C, Chen X, Greilach SA, Walsh CM, Inlay MA. PMID: 37538042; PMCID: PMC10493574.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    2. Ablation of microglia following infection of the central nervous system with a neurotropic murine coronavirus infection leads to increased demyelination and impaired remyelination. J Neuroimmunol. 2023 08 15; 381:578133. Cheng Y, Javonillo DI, Pachow C, Scarfone VM, Fernandez K, Walsh CM, Green KN, Lane TE. PMID: 37352687.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    3. Presentation of Human Neural Stem Cell Antigens Drives Regulatory T Cell Induction. J Immunol. 2023 06 01; 210(11):1677-1686. Greilach SA, McIntyre LL, Nguyen QH, Silva J, Kessenbrock K, Lane TE, Walsh CM. PMID: 37083696; PMCID: PMC10192095.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. Editorial: Editor's Pick 2021: Highlights in Cell Death and Survival. Front Cell Dev Biol. 2022; 10:887688. He YW, Walsh CM. PMID: 35615699; PMCID: PMC9125200.
      View in: PubMed   Mentions:
    5. Regulatory T cells promote remyelination in the murine experimental autoimmune encephalomyelitis model of multiple sclerosis following human neural stem cell transplant. Neurobiol Dis. 2020 07; 140:104868. McIntyre LL, Greilach SA, Othy S, Sears-Kraxberger I, Wi B, Ayala-Angulo J, Vu E, Pham Q, Silva J, Dang K, Rezk F, Steward O, Cahalan MD, Lane TE, Walsh CM. PMID: 32276110; PMCID: PMC7253332.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    6. Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics. Sci Immunol. 2020 02 21; 5(44). Alshetaiwi H, Pervolarakis N, McIntyre LL, Ma D, Nguyen Q, Rath JA, Nee K, Hernandez G, Evans K, Torosian L, Silva A, Walsh C, Kessenbrock K. PMID: 32086381; PMCID: PMC7219211.
      View in: PubMed   Mentions: 173     Fields:    Translation:HumansAnimalsCells
    7. Stem Cell-Derived Exosomes as Nanotherapeutics for Autoimmune and Neurodegenerative Disorders. ACS Nano. 2019 06 25; 13(6):6670-6688. Riazifar M, Mohammadi MR, Pone EJ, Yeri A, Lässer C, Segaliny AI, McIntyre LL, Shelke GV, Hutchins E, Hamamoto A, Calle EN, Crescitelli R, Liao W, Pham V, Yin Y, Jayaraman J, Lakey JRT, Walsh CM, Van Keuren-Jensen K, Lotvall J, Zhao W. PMID: 31117376; PMCID: PMC6880946.
      View in: PubMed   Mentions: 208     Fields:    Translation:HumansAnimalsCells
    8. CD11a expression distinguishes infiltrating myeloid cells from plaque-associated microglia in Alzheimer's disease. Glia. 2019 05; 67(5):844-856. Shukla AK, McIntyre LL, Marsh SE, Schneider CA, Hoover EM, Walsh CM, Lodoen MB, Blurton-Jones M, Inlay MA. PMID: 30588668; PMCID: PMC7375697.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    9. Promoting remyelination through cell transplantation therapies in a model of viral-induced neurodegenerative disease. Dev Dyn. 2019 01; 248(1):43-52. Mangale V, McIntyre LL, Walsh CM, Loring JF, Lane TE. PMID: 30067309; PMCID: PMC6420815.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    10. Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus. Virology. 2017 11; 511:49-55. Mangale V, Marro BS, Plaisted WC, Walsh CM, Lane TE. PMID: 28822268; PMCID: PMC5623645.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    11. Endothelial Wnt/β-catenin signaling reduces immune cell infiltration in multiple sclerosis. Proc Natl Acad Sci U S A. 2017 02 14; 114(7):E1168-E1177. Lengfeld JE, Lutz SE, Smith JR, Diaconu C, Scott C, Kofman SB, Choi C, Walsh CM, Raine CS, Agalliu I, Agalliu D. PMID: 28137846; PMCID: PMC5320985.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    12. Context-Specific Function of S6K2 in Th Cell Differentiation. J Immunol. 2016 10 15; 197(8):3049-3058. Pai C, Walsh CM, Fruman DA. PMID: 27613697; PMCID: PMC5101169.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    13. Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis. PLoS One. 2016; 11(6):e0157620. Plaisted WC, Zavala A, Hingco E, Tran H, Coleman R, Lane TE, Loring JF, Walsh CM. PMID: 27310015; PMCID: PMC4911106.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    14. Mesenchymal stem cells engineered to express selectin ligands and IL-10 exert enhanced therapeutic efficacy in murine experimental autoimmune encephalomyelitis. Biomaterials. 2016 Jan; 77:87-97. Liao W, Pham V, Liu L, Riazifar M, Pone EJ, Zhang SX, Ma F, Lu M, Walsh CM, Zhao W. PMID: 26584349; PMCID: PMC4684451.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    15. Editorial: Tweaking T cell receptor signaling thresholds through DAG: the role of diacylglycerol kinase ζ in T cell responses to TGF-β. J Leukoc Biol. 2015 Nov; 98(5):685-7. Walsh CM. PMID: 26525843.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    16. Two-photon imaging of cellular dynamics in the mouse spinal cord. J Vis Exp. 2015 Feb 22; (96). Weinger JG, Greenberg ML, Matheu MP, Parker I, Walsh CM, Lane TE, Cahalan MD. PMID: 25742043; PMCID: PMC4354666.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    17. Metabolic mysteries of the inflammatory response: T cell polarization and plasticity. Int Rev Immunol. 2015 Jan; 34(1):3-18. Fracchia KM, Walsh CM. PMID: 25398050.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    18. Complement protein C1q bound to apoptotic cells suppresses human macrophage and dendritic cell-mediated Th17 and Th1 T cell subset proliferation. J Leukoc Biol. 2015 Jan; 97(1):147-60. Clarke EV, Weist BM, Walsh CM, Tenner AJ. PMID: 25381385; PMCID: PMC4377823.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    19. Activating receptor NKG2D targets RAE-1-expressing allogeneic neural precursor cells in a viral model of multiple sclerosis. Stem Cells. 2014 Oct; 32(10):2690-701. Weinger JG, Plaisted WC, Maciejewski SM, Lanier LL, Walsh CM, Lane TE. PMID: 24898518; PMCID: PMC4165828.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    20. Too much of a good thing: immunodeficiency due to hyperactive PI3K signaling. J Clin Invest. 2014 Sep; 124(9):3688-90. Walsh CM, Fruman DA. PMID: 25133419; PMCID: PMC4151232.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    21. Necroptotic signaling in adaptive and innate immunity. Semin Cell Dev Biol. 2014 Nov; 35:33-9. Lu JV, Chen HC, Walsh CM. PMID: 25042848; PMCID: PMC4197103.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    22. Functions of caspase 8: the identified and the mysterious. Semin Immunol. 2014 Jun; 26(3):246-52. Salvesen GS, Walsh CM. PMID: 24856110; PMCID: PMC4099255.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    23. Human neural precursor cells promote neurologic recovery in a viral model of multiple sclerosis. Stem Cell Reports. 2014 Jun 03; 2(6):825-37. Chen L, Coleman R, Leang R, Tran H, Kopf A, Walsh CM, Sears-Kraxberger I, Steward O, Macklin WB, Loring JF, Lane TE. PMID: 24936469; PMCID: PMC4050357.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    24. Grand challenges in cell death and survival: apoptosis vs. necroptosis. Front Cell Dev Biol. 2014; 2:3. Walsh CM. PMID: 25364712; PMCID: PMC4206982.
      View in: PubMed   Mentions: 18  
    25. T cell mediated suppression of neurotropic coronavirus replication in neural precursor cells. Virology. 2014 Jan 20; 449:235-43. Plaisted WC, Weinger JG, Walsh CM, Lane TE. PMID: 24418558; PMCID: PMC3894587.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    26. Modulation of T Cell Metabolism and Function through Calcium Signaling. Front Immunol. 2013 Oct 11; 4:324. Fracchia KM, Pai CY, Walsh CM. PMID: 24133495; PMCID: PMC3795426.
      View in: PubMed   Mentions: 53     Fields:    
    27. DRAK2 participates in a negative feedback loop to control TGF-β/Smads signaling by binding to type I TGF-β receptor. Cell Rep. 2012 Nov 29; 2(5):1286-99. Yang KM, Kim W, Bae E, Gim J, Weist BM, Jung Y, Hyun JS, Hernandez JB, Leem SH, Park T, Jeong J, Walsh CM, Kim SJ. PMID: 23122956.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    28. MHC mismatch results in neural progenitor cell rejection following spinal cord transplantation in a model of viral-induced demyelination. Stem Cells. 2012 Nov; 30(11):2584-95. Weinger JG, Weist BM, Plaisted WC, Klaus SM, Walsh CM, Lane TE. PMID: 22969049; PMCID: PMC3479361.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    29. Programmed necrosis and autophagy in immune function. Immunol Rev. 2012 Sep; 249(1):205-17. Lu JV, Walsh CM. PMID: 22889224; PMCID: PMC4030387.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    30. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, et al. PMID: 22966490; PMCID: PMC3404883.
      View in: PubMed   Mentions: 1813     Fields:    Translation:HumansAnimals
    31. Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity. Proc Natl Acad Sci U S A. 2011 Sep 13; 108(37):15312-7. Lu JV, Weist BM, van Raam BJ, Marro BS, Nguyen LV, Srinivas P, Bell BD, Luhrs KA, Lane TE, Salvesen GS, Walsh CM. PMID: 21876153; PMCID: PMC3174674.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    32. Protein kinase D orchestrates the activation of DRAK2 in response to TCR-induced Ca2+ influx and mitochondrial reactive oxygen generation. J Immunol. 2011 Jan 15; 186(2):940-50. Newton RH, Leverrier S, Srikanth S, Gwack Y, Cahalan MD, Walsh CM. PMID: 21148796; PMCID: PMC3133617.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    33. Life and death in the thymus--cell death signaling during T cell development. Curr Opin Cell Biol. 2010 Dec; 22(6):865-71. Hernandez JB, Newton RH, Walsh CM. PMID: 20810263; PMCID: PMC2993787.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    34. The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis. Immunol Rev. 2010 Jul; 236:95-109. Walsh CM, Edinger AL. PMID: 20636811; PMCID: PMC2966323.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    35. T cell intrinsic roles of autophagy in promoting adaptive immunity. Curr Opin Immunol. 2010 Jun; 22(3):321-5. Walsh CM, Bell BD. PMID: 20392618; PMCID: PMC2891069.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    36. Altered thymic selection and increased autoimmunity caused by ectopic expression of DRAK2 during T cell development. J Immunol. 2009 Jul 01; 183(1):285-97. Gatzka M, Newton RH, Walsh CM. PMID: 19542440; PMCID: PMC2724075.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    37. Coordinate regulation of autophagy and apoptosis in T cells by death effectors: FADD or foundation. Autophagy. 2009 Feb; 5(2):238-40. Bell BD, Walsh CM. PMID: 19077534.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    38. Enhanced T cell apoptosis within Drak2-deficient mice promotes resistance to autoimmunity. J Immunol. 2008 Dec 01; 181(11):7606-16. Ramos SJ, Hernandez JB, Gatzka M, Walsh CM. PMID: 19017949; PMCID: PMC2709975.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    39. FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells. Proc Natl Acad Sci U S A. 2008 Oct 28; 105(43):16677-82. Bell BD, Leverrier S, Weist BM, Newton RH, Arechiga AF, Luhrs KA, Morrissette NS, Walsh CM. PMID: 18946037; PMCID: PMC2575479.
      View in: PubMed   Mentions: 163     Fields:    Translation:AnimalsCells
    40. A role for DRAK2 in the germinal center reaction and the antibody response. Autoimmunity. 2008 Aug; 41(5):341-52. Al-Qahtani A, Xu Z, Zan H, Walsh CM, Casali P. PMID: 18568639; PMCID: PMC3140869.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    41. DRAK2 regulates memory T cell responses following murine coronavirus infection. Autoimmunity. 2007 Nov; 40(7):483-8. Schaumburg CS, Gatzka M, Walsh CM, Lane TE. PMID: 17966037.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCellsPHPublic Health
    42. A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2. J Immunol. 2007 Oct 15; 179(8):5291-300. Arechiga AF, Bell BD, Leverrier S, Weist BM, Porter M, Wu Z, Kanno Y, Ramos SJ, Ong ST, Siegel R, Walsh CM. PMID: 17911615.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    43. Apoptotic signal transduction and T cell tolerance. Autoimmunity. 2007 Sep; 40(6):442-52. Gatzka M, Walsh CM. PMID: 17729038.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    44. Signal transduction and autoimmunity: introduction. Autoimmunity. 2007 Sep; 40(6):403-4. Fruman DA, Walsh CM. PMID: 17729032.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    45. Anti-viral effector T cell responses and trafficking are not dependent upon DRAK2 signaling following viral infection of the central nervous system. Autoimmunity. 2007 Feb; 40(1):54-65. Ramos SJ, Hardison JL, Stiles LN, Lane TE, Walsh CM. PMID: 17364498.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    46. Modulation of DRAK2 autophosphorylation by antigen receptor signaling in primary lymphocytes. J Biol Chem. 2007 Feb 16; 282(7):4573-4584. Friedrich ML, Cui M, Hernandez JB, Weist BM, Andersen HM, Zhang X, Huang L, Walsh CM. PMID: 17182616.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    47. GRA1 protein vaccine confers better immune response compared to codon-optimized GRA1 DNA vaccine. Vaccine. 2007 Feb 26; 25(10):1824-37. Döskaya M, Kalantari-Dehaghi M, Walsh CM, Hiszczynska-Sawicka E, Davies DH, Felgner PL, Larsen LS, Lathrop RH, Hatfield GW, Schulz JR, Gürüz Y, Jurnak F. PMID: 17234306.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    48. Emerging roles for the death adaptor FADD in death receptor avidity and cell cycle regulation. Cell Cycle. 2006 Oct; 5(20):2332-8. Werner MH, Wu C, Walsh CM. PMID: 17102623.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    49. CXCR4 tropic human immunodeficiency virus type 1 induces an apoptotic cascade in immature infected thymocytes that resembles thymocyte negative selection. Virology. 2006 Sep 01; 352(2):268-84. Choudhary SK, Walker RM, Powell DM, Planelles V, Walsh C, Camerini D. PMID: 16777169.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    50. Cutting edge: FADD is not required for antigen receptor-mediated NF-kappaB activation. J Immunol. 2005 Dec 15; 175(12):7800-4. Arechiga AF, Bell BD, Solomon JC, Chu IH, Dubois CL, Hall BE, George TC, Coder DM, Walsh CM. PMID: 16339514.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    51. DRAK2, a lymphoid-enriched DAP kinase, regulates the TCR activation threshold during thymocyte selection. Int Immunol. 2005 Nov; 17(11):1379-90. Friedrich ML, Wen BG, Bain G, Kee BL, Katayama C, Murre C, Hedrick SM, Walsh CM. PMID: 16172133.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    52. A deficiency in Drak2 results in a T cell hypersensitivity and an unexpected resistance to autoimmunity. Immunity. 2004 Dec; 21(6):781-91. McGargill MA, Wen BG, Walsh CM, Hedrick SM. PMID: 15589167; PMCID: PMC2792702.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    53. Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin. Cancer Res. 2003 Sep 15; 63(18):5716-22. Ly C, Arechiga AF, Melo JV, Walsh CM, Ong ST. PMID: 14522890.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    54. The "fuzzy logic" of the death-inducing signaling complex in lymphocytes. J Clin Immunol. 2003 Sep; 23(5):333-53. Walsh CM, Luhrs KA, Arechiga AF. PMID: 14601642.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    55. The requirements for Fas-associated death domain signaling in mature T cell activation and survival. J Immunol. 2003 Jul 01; 171(1):247-56. Beisner DR, Chu IH, Arechiga AF, Hedrick SM, Walsh CM. PMID: 12817005.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
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