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Vittorio Sebastiano

Title(s)Professor, Biological Chemistry
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Skin health and biological aging. Nat Aging. 2025 Jul; 5(7):1195-1206. Furman D, Auwerx J, Bulteau AL, Church G, Couturaud V, Crabbe L, Davies KJA, Decottignies A, Gladyshev VN, Kennedy BK, Neretti N, Nizard C, Pays K, Robinton D, Sebastiano V, Watson REB, Wang MC, Woltjen K. PMID: 40527938.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsPHPublic Health
    2. Digital biomarkers of ageing for monitoring physiological systems in community-dwelling adults. Lancet Healthy Longev. 2025 Jun; 6(6):100725. Lu JK, Wang W, Mahadzir MDA, Poganik JR, Moqri M, Herzog C, Verdin E, Sebastiano V, Gladyshev VN, Maier AB, Biomarkers of Aging Consortium. PMID: 40517785.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Improving gene isoform quantification with miniQuant. Nat Biotechnol. 2025 Jun 03. Li H, Wang D, Gao Q, Tan P, Wang Y, Cai X, Li A, Zhao Y, Thurman AL, Malekpour SA, Zhang Y, Sala R, Cipriano A, Wei CL, Sebastiano V, Song C, Zhang NR, Au KF. PMID: 40461779; PMCID: PMC12346831.
      View in: PubMed   Mentions: 1     Fields:    
    4. Distinct type I and II interferon responses direct cortical and medullary thymic epithelial cell development. Sci Immunol. 2025 05 02; 10(107):eado4720. Mohammed A, Wang W, Arreola M, Solomon BD, Slepicka PF, Hubka KM, Nguyen HD, Zheng Z, Chavez MG, Yeh CY, Kim DK, Ma MR, Martin E, Li L, Pasca AM, Winn VD, Gifford CA, Kedlian VR, Park JE, Khatri P, Hollander GA, Roncarolo MG, Sebastiano V, Teichmann SA, Gentles AJ, Weinacht KG. PMID: 40315299.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Transient Epigenetic Reprogramming: The Future of Skin Rejuvenation. Dermatol Surg. 2024 Nov 01; 50(11S):S145-S148. Menon S, Monteleon C, Rhodes ASJ, Sebastiano V, Hsia E. PMID: 39480037.
      View in: PubMed   Mentions:    Fields:    
    6. Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity. Aging (Albany NY). 2024 Oct 16; 16(20):12955-12976. Lyu YX, Fu Q, Wilczok D, Ying K, King A, Antebi A, Vojta A, Stolzing A, Moskalev A, Georgievskaya A, Maier AB, Olsen A, Groth A, Simon AK, Brunet A, Jamil A, Kulaga A, Bhatti A, Yaden B, Pedersen BK, Schumacher B, Djordjevic B, Kennedy B, Chen C, Huang CY, Correll CU, Murphy CT, Ewald CY, Chen D, Valenzano DR, Soldacki D, Erritzoe D, Meyer D, Sinclair DA, Chini EN, Teeling EC, Morgen E, Verdin E, Vernet E, Pinilla E, Fang EF, Bischof E, Mercken EM, Finger F, Kuipers F, Pun FW, Gyülveszi G, Civiletto G, Zmudze G, Blander G, Pincus HA, McClure J, Kirkland JL, Peyer J, Justice JN, Vijg J, Gruhn JR, McLaughlin J, Mannick J, Passos J, Baur JA, Betts-LaCroix J, Sedivy JM, Speakman JR, Shlain J, von Maltzahn J, Andreasson KI, Moody K, Palikaras K, Fortney K, Niedernhofer LJ, Rasmussen LJ, Veenhoff LM, Melton L, Ferrucci L, Quarta M, Koval M, Marinova M, Hamalainen M, Unfried M, Ringel MS, Filipovic M, Topors M, Mitin N, Roy N, Pintar N, Barzilai N, Binetti P, Singh P, Kohlhaas P, Robbins PD, Rubin P, Fedichev PO, Kamya P, Muñoz-Canoves P, de Cabo R, Faragher RGA, Konrad R, Ripa R, Mansukhani R, Büttner S, Wickström SA, Brunemeier S, Jakimov S, Luo S, Rosenzweig-Lipson S, Tsai SY, Dimmeler S, Rando TA, Peterson TR, Woods T, Wyss-Coray T, Finkel T, Strauss T, Gladyshev VN, Longo VD, Dwaraka VB, Gorbunova V, Acosta-Rodríguez VA, Sorrentino V, Sebastiano V, Li W, Suh Y, Zhavoronkov A, Scheibye-Knudsen M, Bakula D. PMID: 39418098; PMCID: PMC11552646.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    7. Challenges and recommendations for the translation of biomarkers of aging. Nat Aging. 2024 Oct; 4(10):1372-1383. Biomarkers of Aging Consortium, Herzog CMS, Goeminne LJE, Poganik JR, Barzilai N, Belsky DW, Betts-LaCroix J, Chen BH, Chen M, Cohen AA, Cummings SR, Fedichev PO, Ferrucci L, Fleming A, Fortney K, Furman D, Gorbunova V, Higgins-Chen A, Hood L, Horvath S, Justice JN, Kiel DP, Kuchel GA, Lasky-Su J, LeBrasseur NK, Maier AB, Schilling B, Sebastiano V, Slagboom PE, Snyder MP, Verdin E, Widschwendter M, Zhavoronkov A, Moqri M, Gladyshev VN. PMID: 39285015; PMCID: PMC12262637.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    8. Transcriptional and epigenetic characterization of a new in vitro platform to model the formation of human pharyngeal endoderm. Genome Biol. 2024 Aug 08; 25(1):211. Cipriano A, Colantoni A, Calicchio A, Fiorentino J, Gomes D, Moqri M, Parker A, Rasouli S, Caldwell M, Briganti F, Roncarolo MG, Baldini A, Weinacht KG, Tartaglia GG, Sebastiano V. PMID: 39118163; PMCID: PMC11312149.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. PRC2-AgeIndex as a universal biomarker of aging and rejuvenation. Nat Commun. 2024 Jul 16; 15(1):5956. Moqri M, Cipriano A, Simpson DJ, Rasouli S, Murty T, de Jong TA, Nachun D, de Sena Brandine G, Ying K, Tarkhov A, Aberg KA, van den Oord E, Zhou W, Smith A, Mackall C, Gladyshev VN, Horvath S, Snyder MP, Sebastiano V. PMID: 39009581; PMCID: PMC11250797.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    10. Validation of biomarkers of aging. Nat Med. 2024 02; 30(2):360-372. Moqri M, Herzog C, Poganik JR, Ying K, Justice JN, Belsky DW, Higgins-Chen AT, Chen BH, Cohen AA, Fuellen G, Hägg S, Marioni RE, Widschwendter M, Fortney K, Fedichev PO, Zhavoronkov A, Barzilai N, Lasky-Su J, Kiel DP, Kennedy BK, Cummings S, Slagboom PE, Verdin E, Maier AB, Sebastiano V, Snyder MP, Gladyshev VN, Horvath S, Ferrucci L. PMID: 38355974; PMCID: PMC11090477.
      View in: PubMed   Mentions: 114     Fields:    
    11. Publisher Correction: Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nat Aging. 2024 Feb; 4(2):275. Cipriano A, Moqri M, Maybury-Lewis SY, Rogers-Hammond R, de Jong TA, Parker A, Rasouli S, Schöler HR, Sinclair DA, Sebastiano V. PMID: 38177331.
      View in: PubMed   Mentions:    Fields:    
    12. Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nat Aging. 2024 Jan; 4(1):14-26. Cipriano A, Moqri M, Maybury-Lewis SY, Rogers-Hammond R, de Jong TA, Parker A, Rasouli S, Schöler HR, Sinclair DA, Sebastiano V. PMID: 38102454; PMCID: PMC11058000.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    13. Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation. Mol Cell. 2023 12 07; 83(23):4255-4271.e9. Torre D, Fstkchyan YS, Ho JSY, Cheon Y, Patel RS, Degrace EJ, Mzoughi S, Schwarz M, Mohammed K, Seo JS, Romero-Bueno R, Demircioglu D, Hasson D, Tang W, Mahajani SU, Campisi L, Zheng S, Song WS, Wang YC, Shah H, Francoeur N, Soto J, Salfati Z, Weirauch MT, Warburton P, Beaumont K, Smith ML, Mulder L, Villalta SA, Kessenbrock K, Jang C, Lee D, De Rubeis S, Cobos I, Tam O, Hammell MG, Seldin M, Shi Y, Basu U, Sebastiano V, Byun M, Sebra R, Rosenberg BR, Benner C, Guccione E, Marazzi I. PMID: 37995687; PMCID: PMC10842741.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    14. Monolayer platform to generate and purify primordial germ-like cells in vitro provides insights into human germline specification. Nat Commun. 2023 09 14; 14(1):5690. Vijayakumar S, Sala R, Kang G, Chen A, Pablo MA, Adebayo AI, Cipriano A, Fowler JL, Gomes DL, Ang LT, Loh KM, Sebastiano V. PMID: 37709760; PMCID: PMC10502105.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    15. Biomarkers of aging for the identification and evaluation of longevity interventions. Cell. 2023 08 31; 186(18):3758-3775. Moqri M, Herzog C, Poganik JR, Biomarkers of Aging Consortium, Justice J, Belsky DW, Higgins-Chen A, Moskalev A, Fuellen G, Cohen AA, Bautmans I, Widschwendter M, Ding J, Fleming A, Mannick J, Han JJ, Zhavoronkov A, Barzilai N, Kaeberlein M, Cummings S, Kennedy BK, Ferrucci L, Horvath S, Verdin E, Maier AB, Snyder MP, Sebastiano V, Gladyshev VN. PMID: 37657418; PMCID: PMC11088934.
      View in: PubMed   Mentions: 221     Fields:    Translation:Humans
    16. Editorial: Germ cell development and reproductive aging. Front Cell Dev Biol. 2022; 10:1051539. Brieño-Enriquez MA, Duncan FE, Ghazi A, Klutstein M, Sebastiano V, Tyler J. PMID: 36313559; PMCID: PMC9597615.
      View in: PubMed   Mentions: 2  
    17. We Shall See? N Engl J Med. 2021 May 06; 384(18):1766-1768. Sebastiano V, Zack DJ. PMID: 33951368.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    18. Author Correction: CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep. Sci Rep. 2020 May 05; 10(1):7500. Vilarino M, Rashid ST, Suchy FP, McNabb BR, van der Meulen T, Fine EJ, Ahsan SD, Mursaliyev N, Sebastiano V, Diab SS, Huising MO, Nakauchi H, Ross PJ. PMID: 32371904; PMCID: PMC7200707.
      View in: PubMed   Mentions: 1     Fields:    
    19. Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells. Nat Commun. 2020 03 24; 11(1):1545. Sarkar TJ, Quarta M, Mukherjee S, Colville A, Paine P, Doan L, Tran CM, Chu CR, Horvath S, Qi LS, Bhutani N, Rando TA, Sebastiano V. PMID: 32210226; PMCID: PMC7093390.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansAnimalsCells
    20. Platelet-Rich Plasma (PRP) From Older Males With Knee Osteoarthritis Depresses Chondrocyte Metabolism and Upregulates Inflammation. J Orthop Res. 2019 08; 37(8):1760-1770. O'Donnell C, Migliore E, Grandi FC, Koltsov J, Lingampalli N, Cisar C, Indelli PF, Sebastiano V, Robinson WH, Bhutani N, Chu CR. PMID: 31042308; PMCID: PMC6824920.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    21. Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. Cell Stem Cell. 2019 05 02; 24(5):821-828.e5. Martin RM, Ikeda K, Cromer MK, Uchida N, Nishimura T, Romano R, Tong AJ, Lemgart VT, Camarena J, Pavel-Dinu M, Sindhu C, Wiebking V, Vaidyanathan S, Dever DP, Bak RO, Laustsen A, Lesch BJ, Jakobsen MR, Sebastiano V, Nakauchi H, Porteus MH. PMID: 31051134.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansCells
    22. Replication study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Elife. 2018 12 11; 7. Kim J, Afshari A, Sengupta R, Sebastiano V, Gupta A, Kim YH, Reproducibility Project: Cancer Biology. PMID: 30526855; PMCID: PMC6289570.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    23. Honey bee Royalactin unlocks conserved pluripotency pathway in mammals. Nat Commun. 2018 12 04; 9(1):5078. Wan DC, Morgan SL, Spencley AL, Mariano N, Chang EY, Shankar G, Luo Y, Li TH, Huh D, Huynh SK, Garcia JM, Dovey CM, Lumb J, Liu L, Brown KV, Bermudez A, Luong R, Zeng H, Mascetti VL, Pitteri SJ, Wang J, Tu H, Quarta M, Sebastiano V, Nusse R, Rando TA, Carette JE, Bazan JF, Wang KC. PMID: 30510260; PMCID: PMC6277453.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    24. Efficient scarless genome editing in human pluripotent stem cells. Nat Methods. 2018 12; 15(12):1045-1047. Ikeda K, Uchida N, Nishimura T, White J, Martin RM, Nakauchi H, Sebastiano V, Weinberg KI, Porteus MH. PMID: 30504872.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    25. A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells. Nat Commun. 2018 10 22; 9(1):4384. Fang F, Xia N, Angulo B, Carey J, Cady Z, Durruthy-Durruthy J, Bennett T, Sebastiano V, Reijo Pera RA. PMID: 30349051; PMCID: PMC6197280.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    26. Influenza virus infection causes global RNAPII termination defects. Nat Struct Mol Biol. 2018 09; 25(9):885-893. Zhao N, Sebastiano V, Moshkina N, Mena N, Hultquist J, Jimenez-Morales D, Ma Y, Rialdi A, Albrecht R, Fenouil R, Sánchez-Aparicio MT, Ayllon J, Ravisankar S, Haddad B, Ho JSY, Low D, Jin J, Yurchenko V, Prinjha RK, Tarakhovsky A, Squatrito M, Pinto D, Allette K, Byun M, Smith ML, Sebra R, Guccione E, Tumpey T, Krogan N, Greenbaum B, van Bakel H, García-Sastre A, Marazzi I. PMID: 30177761; PMCID: PMC10754036.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    27. Do Induced Pluripotent Stem Cell Characteristics Correlate with Efficient In Vitro Smooth Muscle Cell Differentiation? A Comparison of Three Patient-Derived Induced Pluripotent Stem Cell Lines. Stem Cells Dev. 2018 10 15; 27(20):1438-1448. Zhou Y, Kang G, Wen Y, Briggs M, Sebastiano V, Pederson R, Chen B. PMID: 30153084.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    28. NKX3-1 is required for induced pluripotent stem cell reprogramming and can replace OCT4 in mouse and human iPSC induction. Nat Cell Biol. 2018 08; 20(8):900-908. Mai T, Markov GJ, Brady JJ, Palla A, Zeng H, Sebastiano V, Blau HM. PMID: 30013107; PMCID: PMC6101038.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    29. Single cell expression analysis of primate-specific retroviruses-derived HPAT lincRNAs in viable human blastocysts identifies embryonic cells co-expressing genetic markers of multiple lineages. Heliyon. 2018 Jun; 4(6):e00667. Glinsky G, Durruthy-Durruthy J, Wossidlo M, Grow EJ, Weirather JL, Au KF, Wysocka J, Sebastiano V. PMID: 30003161; PMCID: PMC6039856.
      View in: PubMed   Mentions: 12  
    30. Use of human-derived stem cells to create a novel, in vitro model designed to explore FMR1 CGG repeat instability amongst female premutation carriers. J Assist Reprod Genet. 2018 Aug; 35(8):1443-1455. Gustin SLF, Wang G, Baker VM, Latham G, Sebastiano V. PMID: 29926373; PMCID: PMC6086796.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    31. CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep. Sci Rep. 2017 Dec 12; 7(1):17472. Vilarino M, Rashid ST, Suchy FP, McNabb BR, van der Meulen T, Fine EJ, Ahsan SD, Mursaliyev N, Sebastiano V, Diab SS, Huising MO, Nakauchi H, Ross PJ. PMID: 29234093; PMCID: PMC5727233.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    32. A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases. Circ Res. 2017 May 12; 120(10):1561-1571. Karakikes I, Termglinchan V, Cepeda DA, Lee J, Diecke S, Hendel A, Itzhaki I, Ameen M, Shrestha R, Wu H, Ma N, Shao NY, Seeger T, Woo N, Wilson KD, Matsa E, Porteus MH, Sebastiano V, Wu JC. PMID: 28246128; PMCID: PMC5429194.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    33. Comprehensive comparison of Pacific Biosciences and Oxford Nanopore Technologies and their applications to transcriptome analysis. F1000Res. 2017; 6:100. Weirather JL, de Cesare M, Wang Y, Piazza P, Sebastiano V, Wang XJ, Buck D, Au KF. PMID: 28868132; PMCID: PMC5553090.
      View in: PubMed   Mentions: 248     Fields:    
    34. A semi-interpenetrating network of polyacrylamide and recombinant basement membrane allows pluripotent cell culture in a soft, ligand-rich microenvironment. Biomaterials. 2017 03; 121:179-192. Price AJ, Huang EY, Sebastiano V, Dunn AR. PMID: 28088685.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    35. Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency. Dev Cell. 2016 07 11; 38(1):100-15. Durruthy-Durruthy J, Wossidlo M, Pai S, Takahashi Y, Kang G, Omberg L, Chen B, Nakauchi H, Reijo Pera R, Sebastiano V. PMID: 27404362.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    36. YAP Induces Human Naive Pluripotency. Cell Rep. 2016 Mar 15; 14(10):2301-12. Qin H, Hejna M, Liu Y, Percharde M, Wossidlo M, Blouin L, Durruthy-Durruthy J, Wong P, Qi Z, Yu J, Qi LS, Sebastiano V, Song JS, Ramalho-Santos M. PMID: 26947063; PMCID: PMC4807727.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansCells
    37. Patenting parthenotes in the US and Europe. Nat Biotechnol. 2015 Dec 09; 33(12):1232-1234. Senatore V, Scott CT, Sebastiano V. PMID: 26650007.
      View in: PubMed   Mentions:    Fields:    
    38. The primate-specific noncoding RNA HPAT5 regulates pluripotency during human preimplantation development and nuclear reprogramming. Nat Genet. 2016 Jan; 48(1):44-52. Durruthy-Durruthy J, Sebastiano V, Wossidlo M, Cepeda D, Cui J, Grow EJ, Davila J, Mall M, Wong WH, Wysocka J, Au KF, Reijo Pera RA. PMID: 26595768; PMCID: PMC4827613.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    39. Lift NIH restrictions on chimera research. Science. 2015 Nov 06; 350(6261):640. Sharma A, Sebastiano V, Scott CT, Magnus D, Koyano-Nakagawa N, Garry DJ, Witte ON, Nakauchi H, Wu JC, Weissman IL, Wu SM. PMID: 26542560.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    40. Derivation of GMP-compliant integration-free hiPSCs using modified mRNAs. Methods Mol Biol. 2015; 1283:31-42. Durruthy JD, Sebastiano V. PMID: 25304205.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    41. Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa. Sci Transl Med. 2014 Nov 26; 6(264):264ra163. Sebastiano V, Zhen HH, Haddad B, Derafshi BH, Bashkirova E, Melo SP, Wang P, Leung TL, Siprashvili Z, Tichy A, Li J, Ameen M, Hawkins J, Lee S, Li L, Schwertschkow A, Bauer G, Lisowski L, Kay MA, Kim SK, Lane AT, Wernig M, Oro AE. PMID: 25429056; PMCID: PMC4428910.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimalsCells
    42. The transcriptome of human pluripotent stem cells. Curr Opin Genet Dev. 2014 Oct; 28:71-7. Au KF, Sebastiano V. PMID: 25461453.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    43. Germ cell nuclear factor regulates gametogenesis in developing gonads. PLoS One. 2014; 9(8):e103985. Sabour D, Xu X, Chung AC, Le Menuet D, Ko K, Tapia N, Araúzo-Bravo MJ, Gentile L, Greber B, Hübner K, Sebastiano V, Wu G, Schöler HR, Cooney AJ. PMID: 25140725; PMCID: PMC4139263.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    44. Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions. PLoS One. 2014; 9(4):e94231. Durruthy-Durruthy J, Briggs SF, Awe J, Ramathal CY, Karumbayaram S, Lee PC, Heidmann JD, Clark A, Karakikes I, Loh KM, Wu JC, Hoffman AR, Byrne J, Reijo Pera RA, Sebastiano V. PMID: 24718618; PMCID: PMC3981795.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    45. Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing. Cell Rep. 2014 Apr 10; 7(1):293-305. Hendel A, Kildebeck EJ, Fine EJ, Clark J, Punjya N, Sebastiano V, Bao G, Porteus MH. PMID: 24685129; PMCID: PMC4015468.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    46. Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations. Cell Stem Cell. 2014 Feb 06; 14(2):237-52. Loh KM, Ang LT, Zhang J, Kumar V, Ang J, Auyeong JQ, Lee KL, Choo SH, Lim CY, Nichane M, Tan J, Noghabi MS, Azzola L, Ng ES, Durruthy-Durruthy J, Sebastiano V, Poellinger L, Elefanty AG, Stanley EG, Chen Q, Prabhakar S, Weissman IL, Lim B. PMID: 24412311; PMCID: PMC4045507.
      View in: PubMed   Mentions: 212     Fields:    Translation:HumansAnimalsCells
    47. Characterization of the human ESC transcriptome by hybrid sequencing. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):E4821-30. Au KF, Sebastiano V, Afshar PT, Durruthy JD, Lee L, Williams BA, van Bakel H, Schadt EE, Reijo-Pera RA, Underwood JG, Wong WH. PMID: 24282307; PMCID: PMC3864310.
      View in: PubMed   Mentions: 180     Fields:    Translation:HumansCells
    48. SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients. Nature. 2013 Nov 14; 503(7475):267-71. Shcheglovitov A, Shcheglovitova O, Yazawa M, Portmann T, Shu R, Sebastiano V, Krawisz A, Froehlich W, Bernstein JA, Hallmayer JF, Dolmetsch RE. PMID: 24132240; PMCID: PMC5559273.
      View in: PubMed   Mentions: 262     Fields:    Translation:HumansCells
    49. Establishment of totipotency does not depend on Oct4A. Nat Cell Biol. 2013 Sep; 15(9):1089-97. Wu G, Han D, Gong Y, Sebastiano V, Gentile L, Singhal N, Adachi K, Fischedick G, Ortmeier C, Sinn M, Radstaak M, Tomilin A, Schöler HR. PMID: 23934214; PMCID: PMC3845671.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    50. Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. Stem Cell Res Ther. 2013 Jul 26; 4(4):87. Awe JP, Lee PC, Ramathal C, Vega-Crespo A, Durruthy-Durruthy J, Cooper A, Karumbayaram S, Lowry WE, Clark AT, Zack JA, Sebastiano V, Kohn DB, Pyle AD, Martin MG, Lipshutz GS, Phelps PE, Pera RA, Byrne JA. PMID: 23890092; PMCID: PMC3854769.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    51. Human amniotic mesenchymal stem cell-derived induced pluripotent stem cells may generate a universal source of cardiac cells. Stem Cells Dev. 2012 Oct 10; 21(15):2798-808. Ge X, Wang IN, Toma I, Sebastiano V, Liu J, Butte MJ, Reijo Pera RA, Yang PC. PMID: 22530853; PMCID: PMC3464077.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    52. In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases. Stem Cells. 2011 Nov; 29(11):1717-26. Sebastiano V, Maeder ML, Angstman JF, Haddad B, Khayter C, Yeo DT, Goodwin MJ, Hawkins JS, Ramirez CL, Batista LF, Artandi SE, Wernig M, Joung JK. PMID: 21898685; PMCID: PMC3285772.
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    53. Induction of human neuronal cells by defined transcription factors. Nature. 2011 May 26; 476(7359):220-3. Pang ZP, Yang N, Vierbuchen T, Ostermeier A, Fuentes DR, Yang TQ, Citri A, Sebastiano V, Marro S, Südhof TC, Wernig M. PMID: 21617644; PMCID: PMC3159048.
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    54. Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. Nature. 2011 May 22; 474(7351):399-402. Batista LF, Pech MF, Zhong FL, Nguyen HN, Xie KT, Zaug AJ, Crary SM, Choi J, Sebastiano V, Cherry A, Giri N, Wernig M, Alter BP, Cech TR, Savage SA, Reijo Pera RA, Artandi SE. PMID: 21602826; PMCID: PMC3155806.
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    55. Embryonic stem cells, derived either after in vitro fertilization or nuclear transfer, prolong survival of semiallogeneic heart transplants. J Immunol. 2011 Apr 01; 186(7):4164-74. Imberti B, Casiraghi F, Cugini D, Azzollini N, Cassis P, Todeschini M, Solini S, Sebastiano V, Zuccotti M, Garagna S, Redi CA, Noris M, Morigi M, Remuzzi G. PMID: 21389254.
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    56. Ultrastructural characterization of mouse embryonic stem cell-derived oocytes and granulosa cells. Stem Cells Dev. 2011 Dec; 20(12):2205-15. Psathaki OE, Hübner K, Sabour D, Sebastiano V, Wu G, Sugawa F, Wieacker P, Pennekamp P, Schöler HR. PMID: 21244227.
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    57. Oct1 regulates trophoblast development during early mouse embryogenesis. Development. 2010 Nov; 137(21):3551-60. Sebastiano V, Dalvai M, Gentile L, Schubart K, Sutter J, Wu GM, Tapia N, Esch D, Ju JY, Hübner K, Bravo MJ, Schöler HR, Cavaleri F, Matthias P. PMID: 20876643.
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    58. Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes. EMBO J. 2010 Jun 02; 29(11):1877-88. Wossidlo M, Arand J, Sebastiano V, Lepikhov K, Boiani M, Reinhardt R, Schöler H, Walter J. PMID: 20442707; PMCID: PMC2885932.
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    59. Induction of pluripotency in adult unipotent germline stem cells. Cell Stem Cell. 2009 Jul 02; 5(1):87-96. Ko K, Tapia N, Wu G, Kim JB, Bravo MJ, Sasse P, Glaser T, Ruau D, Han DW, Greber B, Hausdörfer K, Sebastiano V, Stehling M, Fleischmann BK, Brüstle O, Zenke M, Schöler HR. PMID: 19570517.
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    60. Oct4-induced pluripotency in adult neural stem cells. Cell. 2009 Feb 06; 136(3):411-9. Kim JB, Sebastiano V, Wu G, Araúzo-Bravo MJ, Sasse P, Gentile L, Ko K, Ruau D, Ehrich M, van den Boom D, Meyer J, Hübner K, Bernemann C, Ortmeier C, Zenke M, Fleischmann BK, Zaehres H, Schöler HR. PMID: 19203577.
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    61. Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature. 2008 Jul 31; 454(7204):646-50. Kim JB, Zaehres H, Wu G, Gentile L, Ko K, Sebastiano V, Araúzo-Bravo MJ, Ruau D, Han DW, Zenke M, Schöler HR. PMID: 18594515.
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    62. Experimental demonstration that mammalian oocytes are not selective towards X- or Y-bearing sperm. Mol Reprod Dev. 2005 Jun; 71(2):245-6. Zuccotti M, Sebastiano V, Garagna S, Redi CA. PMID: 15791593.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    63. Cloned pre-implantation mouse embryos show correct timing but altered levels of gene expression. Mol Reprod Dev. 2005 Feb; 70(2):146-54. Sebastiano V, Gentile L, Garagna S, Redi CA, Zuccotti M. PMID: 15570622.
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    64. Three-dimensional localization and dynamics of centromeres in mouse oocytes during folliculogenesis. J Mol Histol. 2004 Aug; 35(6):631-8. Garagna S, Merico V, Sebastiano V, Monti M, Orlandini G, Gatti R, Scandroglio R, Redi CA, Zuccotti M. PMID: 15614617.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    65. Single-cell quantitative RT-PCR analysis of Cpt1b and Cpt2 gene expression in mouse antral oocytes and in preimplantation embryos. Cytogenet Genome Res. 2004; 105(2-4):215-21. Gentile L, Monti M, Sebastiano V, Merico V, Nicolai R, Calvani M, Garagna S, Redi CA, Zuccotti M. PMID: 15237209.
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