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Skin health and biological aging. Nat Aging. 2025 Jul; 5(7):1195-1206.
Furman D, Auwerx J, Bulteau AL, Church G, Couturaud V, Crabbe L, Davies KJA, Decottignies A, Gladyshev VN, Kennedy BK, Neretti N, Nizard C, Pays K, Robinton D, Sebastiano V, Watson REB, Wang MC, Woltjen K. PMID: 40527938.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsPHPublic Health
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Digital biomarkers of ageing for monitoring physiological systems in community-dwelling adults. Lancet Healthy Longev. 2025 Jun; 6(6):100725.
Lu JK, Wang W, Mahadzir MDA, Poganik JR, Moqri M, Herzog C, Verdin E, Sebastiano V, Gladyshev VN, Maier AB, Biomarkers of Aging Consortium. PMID: 40517785.
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PubMed Mentions: Fields:
Translation:
Humans
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Improving gene isoform quantification with miniQuant. Nat Biotechnol. 2025 Jun 03.
Li H, Wang D, Gao Q, Tan P, Wang Y, Cai X, Li A, Zhao Y, Thurman AL, Malekpour SA, Zhang Y, Sala R, Cipriano A, Wei CL, Sebastiano V, Song C, Zhang NR, Au KF. PMID: 40461779; PMCID: PMC12346831.
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PubMed Mentions:
1 Fields:
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Distinct type I and II interferon responses direct cortical and medullary thymic epithelial cell development. Sci Immunol. 2025 05 02; 10(107):eado4720.
Mohammed A, Wang W, Arreola M, Solomon BD, Slepicka PF, Hubka KM, Nguyen HD, Zheng Z, Chavez MG, Yeh CY, Kim DK, Ma MR, Martin E, Li L, Pasca AM, Winn VD, Gifford CA, Kedlian VR, Park JE, Khatri P, Hollander GA, Roncarolo MG, Sebastiano V, Teichmann SA, Gentles AJ, Weinacht KG. PMID: 40315299.
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Translation:
HumansCells
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Transient Epigenetic Reprogramming: The Future of Skin Rejuvenation. Dermatol Surg. 2024 Nov 01; 50(11S):S145-S148.
Menon S, Monteleon C, Rhodes ASJ, Sebastiano V, Hsia E. PMID: 39480037.
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PubMed Mentions: Fields:
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Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity. Aging (Albany NY). 2024 Oct 16; 16(20):12955-12976.
Lyu YX, Fu Q, Wilczok D, Ying K, King A, Antebi A, Vojta A, Stolzing A, Moskalev A, Georgievskaya A, Maier AB, Olsen A, Groth A, Simon AK, Brunet A, Jamil A, Kulaga A, Bhatti A, Yaden B, Pedersen BK, Schumacher B, Djordjevic B, Kennedy B, Chen C, Huang CY, Correll CU, Murphy CT, Ewald CY, Chen D, Valenzano DR, Soldacki D, Erritzoe D, Meyer D, Sinclair DA, Chini EN, Teeling EC, Morgen E, Verdin E, Vernet E, Pinilla E, Fang EF, Bischof E, Mercken EM, Finger F, Kuipers F, Pun FW, Gyülveszi G, Civiletto G, Zmudze G, Blander G, Pincus HA, McClure J, Kirkland JL, Peyer J, Justice JN, Vijg J, Gruhn JR, McLaughlin J, Mannick J, Passos J, Baur JA, Betts-LaCroix J, Sedivy JM, Speakman JR, Shlain J, von Maltzahn J, Andreasson KI, Moody K, Palikaras K, Fortney K, Niedernhofer LJ, Rasmussen LJ, Veenhoff LM, Melton L, Ferrucci L, Quarta M, Koval M, Marinova M, Hamalainen M, Unfried M, Ringel MS, Filipovic M, Topors M, Mitin N, Roy N, Pintar N, Barzilai N, Binetti P, Singh P, Kohlhaas P, Robbins PD, Rubin P, Fedichev PO, Kamya P, Muñoz-Canoves P, de Cabo R, Faragher RGA, Konrad R, Ripa R, Mansukhani R, Büttner S, Wickström SA, Brunemeier S, Jakimov S, Luo S, Rosenzweig-Lipson S, Tsai SY, Dimmeler S, Rando TA, Peterson TR, Woods T, Wyss-Coray T, Finkel T, Strauss T, Gladyshev VN, Longo VD, Dwaraka VB, Gorbunova V, Acosta-Rodríguez VA, Sorrentino V, Sebastiano V, Li W, Suh Y, Zhavoronkov A, Scheibye-Knudsen M, Bakula D. PMID: 39418098; PMCID: PMC11552646.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Challenges and recommendations for the translation of biomarkers of aging. Nat Aging. 2024 Oct; 4(10):1372-1383.
Biomarkers of Aging Consortium, Herzog CMS, Goeminne LJE, Poganik JR, Barzilai N, Belsky DW, Betts-LaCroix J, Chen BH, Chen M, Cohen AA, Cummings SR, Fedichev PO, Ferrucci L, Fleming A, Fortney K, Furman D, Gorbunova V, Higgins-Chen A, Hood L, Horvath S, Justice JN, Kiel DP, Kuchel GA, Lasky-Su J, LeBrasseur NK, Maier AB, Schilling B, Sebastiano V, Slagboom PE, Snyder MP, Verdin E, Widschwendter M, Zhavoronkov A, Moqri M, Gladyshev VN. PMID: 39285015; PMCID: PMC12262637.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Transcriptional and epigenetic characterization of a new in vitro platform to model the formation of human pharyngeal endoderm. Genome Biol. 2024 Aug 08; 25(1):211.
Cipriano A, Colantoni A, Calicchio A, Fiorentino J, Gomes D, Moqri M, Parker A, Rasouli S, Caldwell M, Briganti F, Roncarolo MG, Baldini A, Weinacht KG, Tartaglia GG, Sebastiano V. PMID: 39118163; PMCID: PMC11312149.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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PRC2-AgeIndex as a universal biomarker of aging and rejuvenation. Nat Commun. 2024 Jul 16; 15(1):5956.
Moqri M, Cipriano A, Simpson DJ, Rasouli S, Murty T, de Jong TA, Nachun D, de Sena Brandine G, Ying K, Tarkhov A, Aberg KA, van den Oord E, Zhou W, Smith A, Mackall C, Gladyshev VN, Horvath S, Snyder MP, Sebastiano V. PMID: 39009581; PMCID: PMC11250797.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Validation of biomarkers of aging. Nat Med. 2024 02; 30(2):360-372.
Moqri M, Herzog C, Poganik JR, Ying K, Justice JN, Belsky DW, Higgins-Chen AT, Chen BH, Cohen AA, Fuellen G, Hägg S, Marioni RE, Widschwendter M, Fortney K, Fedichev PO, Zhavoronkov A, Barzilai N, Lasky-Su J, Kiel DP, Kennedy BK, Cummings S, Slagboom PE, Verdin E, Maier AB, Sebastiano V, Snyder MP, Gladyshev VN, Horvath S, Ferrucci L. PMID: 38355974; PMCID: PMC11090477.
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PubMed Mentions:
114 Fields:
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Publisher Correction: Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nat Aging. 2024 Feb; 4(2):275.
Cipriano A, Moqri M, Maybury-Lewis SY, Rogers-Hammond R, de Jong TA, Parker A, Rasouli S, Schöler HR, Sinclair DA, Sebastiano V. PMID: 38177331.
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PubMed Mentions: Fields:
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Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nat Aging. 2024 Jan; 4(1):14-26.
Cipriano A, Moqri M, Maybury-Lewis SY, Rogers-Hammond R, de Jong TA, Parker A, Rasouli S, Schöler HR, Sinclair DA, Sebastiano V. PMID: 38102454; PMCID: PMC11058000.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation. Mol Cell. 2023 12 07; 83(23):4255-4271.e9.
Torre D, Fstkchyan YS, Ho JSY, Cheon Y, Patel RS, Degrace EJ, Mzoughi S, Schwarz M, Mohammed K, Seo JS, Romero-Bueno R, Demircioglu D, Hasson D, Tang W, Mahajani SU, Campisi L, Zheng S, Song WS, Wang YC, Shah H, Francoeur N, Soto J, Salfati Z, Weirauch MT, Warburton P, Beaumont K, Smith ML, Mulder L, Villalta SA, Kessenbrock K, Jang C, Lee D, De Rubeis S, Cobos I, Tam O, Hammell MG, Seldin M, Shi Y, Basu U, Sebastiano V, Byun M, Sebra R, Rosenberg BR, Benner C, Guccione E, Marazzi I. PMID: 37995687; PMCID: PMC10842741.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Monolayer platform to generate and purify primordial germ-like cells in vitro provides insights into human germline specification. Nat Commun. 2023 09 14; 14(1):5690.
Vijayakumar S, Sala R, Kang G, Chen A, Pablo MA, Adebayo AI, Cipriano A, Fowler JL, Gomes DL, Ang LT, Loh KM, Sebastiano V. PMID: 37709760; PMCID: PMC10502105.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Biomarkers of aging for the identification and evaluation of longevity interventions. Cell. 2023 08 31; 186(18):3758-3775.
Moqri M, Herzog C, Poganik JR, Biomarkers of Aging Consortium, Justice J, Belsky DW, Higgins-Chen A, Moskalev A, Fuellen G, Cohen AA, Bautmans I, Widschwendter M, Ding J, Fleming A, Mannick J, Han JJ, Zhavoronkov A, Barzilai N, Kaeberlein M, Cummings S, Kennedy BK, Ferrucci L, Horvath S, Verdin E, Maier AB, Snyder MP, Sebastiano V, Gladyshev VN. PMID: 37657418; PMCID: PMC11088934.
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PubMed Mentions:
221 Fields:
Translation:
Humans
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Editorial: Germ cell development and reproductive aging. Front Cell Dev Biol. 2022; 10:1051539.
Brieño-Enriquez MA, Duncan FE, Ghazi A, Klutstein M, Sebastiano V, Tyler J. PMID: 36313559; PMCID: PMC9597615.
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PubMed Mentions:
2
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We Shall See? N Engl J Med. 2021 May 06; 384(18):1766-1768.
Sebastiano V, Zack DJ. PMID: 33951368.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Author Correction: CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep. Sci Rep. 2020 May 05; 10(1):7500.
Vilarino M, Rashid ST, Suchy FP, McNabb BR, van der Meulen T, Fine EJ, Ahsan SD, Mursaliyev N, Sebastiano V, Diab SS, Huising MO, Nakauchi H, Ross PJ. PMID: 32371904; PMCID: PMC7200707.
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1 Fields:
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Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells. Nat Commun. 2020 03 24; 11(1):1545.
Sarkar TJ, Quarta M, Mukherjee S, Colville A, Paine P, Doan L, Tran CM, Chu CR, Horvath S, Qi LS, Bhutani N, Rando TA, Sebastiano V. PMID: 32210226; PMCID: PMC7093390.
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PubMed Mentions:
139 Fields:
Translation:
HumansAnimalsCells
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Platelet-Rich Plasma (PRP) From Older Males With Knee Osteoarthritis Depresses Chondrocyte Metabolism and Upregulates Inflammation. J Orthop Res. 2019 08; 37(8):1760-1770.
O'Donnell C, Migliore E, Grandi FC, Koltsov J, Lingampalli N, Cisar C, Indelli PF, Sebastiano V, Robinson WH, Bhutani N, Chu CR. PMID: 31042308; PMCID: PMC6824920.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. Cell Stem Cell. 2019 05 02; 24(5):821-828.e5.
Martin RM, Ikeda K, Cromer MK, Uchida N, Nishimura T, Romano R, Tong AJ, Lemgart VT, Camarena J, Pavel-Dinu M, Sindhu C, Wiebking V, Vaidyanathan S, Dever DP, Bak RO, Laustsen A, Lesch BJ, Jakobsen MR, Sebastiano V, Nakauchi H, Porteus MH. PMID: 31051134.
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PubMed Mentions:
123 Fields:
Translation:
HumansCells
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Replication study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Elife. 2018 12 11; 7.
Kim J, Afshari A, Sengupta R, Sebastiano V, Gupta A, Kim YH, Reproducibility Project: Cancer Biology. PMID: 30526855; PMCID: PMC6289570.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Honey bee Royalactin unlocks conserved pluripotency pathway in mammals. Nat Commun. 2018 12 04; 9(1):5078.
Wan DC, Morgan SL, Spencley AL, Mariano N, Chang EY, Shankar G, Luo Y, Li TH, Huh D, Huynh SK, Garcia JM, Dovey CM, Lumb J, Liu L, Brown KV, Bermudez A, Luong R, Zeng H, Mascetti VL, Pitteri SJ, Wang J, Tu H, Quarta M, Sebastiano V, Nusse R, Rando TA, Carette JE, Bazan JF, Wang KC. PMID: 30510260; PMCID: PMC6277453.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Efficient scarless genome editing in human pluripotent stem cells. Nat Methods. 2018 12; 15(12):1045-1047.
Ikeda K, Uchida N, Nishimura T, White J, Martin RM, Nakauchi H, Sebastiano V, Weinberg KI, Porteus MH. PMID: 30504872.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells. Nat Commun. 2018 10 22; 9(1):4384.
Fang F, Xia N, Angulo B, Carey J, Cady Z, Durruthy-Durruthy J, Bennett T, Sebastiano V, Reijo Pera RA. PMID: 30349051; PMCID: PMC6197280.
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PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Influenza virus infection causes global RNAPII termination defects. Nat Struct Mol Biol. 2018 09; 25(9):885-893.
Zhao N, Sebastiano V, Moshkina N, Mena N, Hultquist J, Jimenez-Morales D, Ma Y, Rialdi A, Albrecht R, Fenouil R, Sánchez-Aparicio MT, Ayllon J, Ravisankar S, Haddad B, Ho JSY, Low D, Jin J, Yurchenko V, Prinjha RK, Tarakhovsky A, Squatrito M, Pinto D, Allette K, Byun M, Smith ML, Sebra R, Guccione E, Tumpey T, Krogan N, Greenbaum B, van Bakel H, García-Sastre A, Marazzi I. PMID: 30177761; PMCID: PMC10754036.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Do Induced Pluripotent Stem Cell Characteristics Correlate with Efficient In Vitro Smooth Muscle Cell Differentiation? A Comparison of Three Patient-Derived Induced Pluripotent Stem Cell Lines. Stem Cells Dev. 2018 10 15; 27(20):1438-1448.
Zhou Y, Kang G, Wen Y, Briggs M, Sebastiano V, Pederson R, Chen B. PMID: 30153084.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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NKX3-1 is required for induced pluripotent stem cell reprogramming and can replace OCT4 in mouse and human iPSC induction. Nat Cell Biol. 2018 08; 20(8):900-908.
Mai T, Markov GJ, Brady JJ, Palla A, Zeng H, Sebastiano V, Blau HM. PMID: 30013107; PMCID: PMC6101038.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Single cell expression analysis of primate-specific retroviruses-derived HPAT lincRNAs in viable human blastocysts identifies embryonic cells co-expressing genetic markers of multiple lineages. Heliyon. 2018 Jun; 4(6):e00667.
Glinsky G, Durruthy-Durruthy J, Wossidlo M, Grow EJ, Weirather JL, Au KF, Wysocka J, Sebastiano V. PMID: 30003161; PMCID: PMC6039856.
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PubMed Mentions:
12
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Use of human-derived stem cells to create a novel, in vitro model designed to explore FMR1 CGG repeat instability amongst female premutation carriers. J Assist Reprod Genet. 2018 Aug; 35(8):1443-1455.
Gustin SLF, Wang G, Baker VM, Latham G, Sebastiano V. PMID: 29926373; PMCID: PMC6086796.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep. Sci Rep. 2017 Dec 12; 7(1):17472.
Vilarino M, Rashid ST, Suchy FP, McNabb BR, van der Meulen T, Fine EJ, Ahsan SD, Mursaliyev N, Sebastiano V, Diab SS, Huising MO, Nakauchi H, Ross PJ. PMID: 29234093; PMCID: PMC5727233.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases. Circ Res. 2017 May 12; 120(10):1561-1571.
Karakikes I, Termglinchan V, Cepeda DA, Lee J, Diecke S, Hendel A, Itzhaki I, Ameen M, Shrestha R, Wu H, Ma N, Shao NY, Seeger T, Woo N, Wilson KD, Matsa E, Porteus MH, Sebastiano V, Wu JC. PMID: 28246128; PMCID: PMC5429194.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Comprehensive comparison of Pacific Biosciences and Oxford Nanopore Technologies and their applications to transcriptome analysis. F1000Res. 2017; 6:100.
Weirather JL, de Cesare M, Wang Y, Piazza P, Sebastiano V, Wang XJ, Buck D, Au KF. PMID: 28868132; PMCID: PMC5553090.
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PubMed Mentions:
248 Fields:
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A semi-interpenetrating network of polyacrylamide and recombinant basement membrane allows pluripotent cell culture in a soft, ligand-rich microenvironment. Biomaterials. 2017 03; 121:179-192.
Price AJ, Huang EY, Sebastiano V, Dunn AR. PMID: 28088685.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency. Dev Cell. 2016 07 11; 38(1):100-15.
Durruthy-Durruthy J, Wossidlo M, Pai S, Takahashi Y, Kang G, Omberg L, Chen B, Nakauchi H, Reijo Pera R, Sebastiano V. PMID: 27404362.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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YAP Induces Human Naive Pluripotency. Cell Rep. 2016 Mar 15; 14(10):2301-12.
Qin H, Hejna M, Liu Y, Percharde M, Wossidlo M, Blouin L, Durruthy-Durruthy J, Wong P, Qi Z, Yu J, Qi LS, Sebastiano V, Song JS, Ramalho-Santos M. PMID: 26947063; PMCID: PMC4807727.
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PubMed Mentions:
109 Fields:
Translation:
HumansCells
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Patenting parthenotes in the US and Europe. Nat Biotechnol. 2015 Dec 09; 33(12):1232-1234.
Senatore V, Scott CT, Sebastiano V. PMID: 26650007.
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PubMed Mentions: Fields:
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The primate-specific noncoding RNA HPAT5 regulates pluripotency during human preimplantation development and nuclear reprogramming. Nat Genet. 2016 Jan; 48(1):44-52.
Durruthy-Durruthy J, Sebastiano V, Wossidlo M, Cepeda D, Cui J, Grow EJ, Davila J, Mall M, Wong WH, Wysocka J, Au KF, Reijo Pera RA. PMID: 26595768; PMCID: PMC4827613.
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PubMed Mentions:
93 Fields:
Translation:
HumansAnimalsCells
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Lift NIH restrictions on chimera research. Science. 2015 Nov 06; 350(6261):640.
Sharma A, Sebastiano V, Scott CT, Magnus D, Koyano-Nakagawa N, Garry DJ, Witte ON, Nakauchi H, Wu JC, Weissman IL, Wu SM. PMID: 26542560.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Derivation of GMP-compliant integration-free hiPSCs using modified mRNAs. Methods Mol Biol. 2015; 1283:31-42.
Durruthy JD, Sebastiano V. PMID: 25304205.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa. Sci Transl Med. 2014 Nov 26; 6(264):264ra163.
Sebastiano V, Zhen HH, Haddad B, Derafshi BH, Bashkirova E, Melo SP, Wang P, Leung TL, Siprashvili Z, Tichy A, Li J, Ameen M, Hawkins J, Lee S, Li L, Schwertschkow A, Bauer G, Lisowski L, Kay MA, Kim SK, Lane AT, Wernig M, Oro AE. PMID: 25429056; PMCID: PMC4428910.
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PubMed Mentions:
100 Fields:
Translation:
HumansAnimalsCells
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The transcriptome of human pluripotent stem cells. Curr Opin Genet Dev. 2014 Oct; 28:71-7.
Au KF, Sebastiano V. PMID: 25461453.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Germ cell nuclear factor regulates gametogenesis in developing gonads. PLoS One. 2014; 9(8):e103985.
Sabour D, Xu X, Chung AC, Le Menuet D, Ko K, Tapia N, Araúzo-Bravo MJ, Gentile L, Greber B, Hübner K, Sebastiano V, Wu G, Schöler HR, Cooney AJ. PMID: 25140725; PMCID: PMC4139263.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions. PLoS One. 2014; 9(4):e94231.
Durruthy-Durruthy J, Briggs SF, Awe J, Ramathal CY, Karumbayaram S, Lee PC, Heidmann JD, Clark A, Karakikes I, Loh KM, Wu JC, Hoffman AR, Byrne J, Reijo Pera RA, Sebastiano V. PMID: 24718618; PMCID: PMC3981795.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing. Cell Rep. 2014 Apr 10; 7(1):293-305.
Hendel A, Kildebeck EJ, Fine EJ, Clark J, Punjya N, Sebastiano V, Bao G, Porteus MH. PMID: 24685129; PMCID: PMC4015468.
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PubMed Mentions:
77 Fields:
Translation:
HumansCells
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Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations. Cell Stem Cell. 2014 Feb 06; 14(2):237-52.
Loh KM, Ang LT, Zhang J, Kumar V, Ang J, Auyeong JQ, Lee KL, Choo SH, Lim CY, Nichane M, Tan J, Noghabi MS, Azzola L, Ng ES, Durruthy-Durruthy J, Sebastiano V, Poellinger L, Elefanty AG, Stanley EG, Chen Q, Prabhakar S, Weissman IL, Lim B. PMID: 24412311; PMCID: PMC4045507.
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PubMed Mentions:
212 Fields:
Translation:
HumansAnimalsCells
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Characterization of the human ESC transcriptome by hybrid sequencing. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):E4821-30.
Au KF, Sebastiano V, Afshar PT, Durruthy JD, Lee L, Williams BA, van Bakel H, Schadt EE, Reijo-Pera RA, Underwood JG, Wong WH. PMID: 24282307; PMCID: PMC3864310.
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PubMed Mentions:
180 Fields:
Translation:
HumansCells
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SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients. Nature. 2013 Nov 14; 503(7475):267-71.
Shcheglovitov A, Shcheglovitova O, Yazawa M, Portmann T, Shu R, Sebastiano V, Krawisz A, Froehlich W, Bernstein JA, Hallmayer JF, Dolmetsch RE. PMID: 24132240; PMCID: PMC5559273.
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PubMed Mentions:
262 Fields:
Translation:
HumansCells
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Establishment of totipotency does not depend on Oct4A. Nat Cell Biol. 2013 Sep; 15(9):1089-97.
Wu G, Han D, Gong Y, Sebastiano V, Gentile L, Singhal N, Adachi K, Fischedick G, Ortmeier C, Sinn M, Radstaak M, Tomilin A, Schöler HR. PMID: 23934214; PMCID: PMC3845671.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. Stem Cell Res Ther. 2013 Jul 26; 4(4):87.
Awe JP, Lee PC, Ramathal C, Vega-Crespo A, Durruthy-Durruthy J, Cooper A, Karumbayaram S, Lowry WE, Clark AT, Zack JA, Sebastiano V, Kohn DB, Pyle AD, Martin MG, Lipshutz GS, Phelps PE, Pera RA, Byrne JA. PMID: 23890092; PMCID: PMC3854769.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Human amniotic mesenchymal stem cell-derived induced pluripotent stem cells may generate a universal source of cardiac cells. Stem Cells Dev. 2012 Oct 10; 21(15):2798-808.
Ge X, Wang IN, Toma I, Sebastiano V, Liu J, Butte MJ, Reijo Pera RA, Yang PC. PMID: 22530853; PMCID: PMC3464077.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases. Stem Cells. 2011 Nov; 29(11):1717-26.
Sebastiano V, Maeder ML, Angstman JF, Haddad B, Khayter C, Yeo DT, Goodwin MJ, Hawkins JS, Ramirez CL, Batista LF, Artandi SE, Wernig M, Joung JK. PMID: 21898685; PMCID: PMC3285772.
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PubMed Mentions:
161 Fields:
Translation:
HumansCells
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Induction of human neuronal cells by defined transcription factors. Nature. 2011 May 26; 476(7359):220-3.
Pang ZP, Yang N, Vierbuchen T, Ostermeier A, Fuentes DR, Yang TQ, Citri A, Sebastiano V, Marro S, Südhof TC, Wernig M. PMID: 21617644; PMCID: PMC3159048.
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PubMed Mentions:
715 Fields:
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HumansAnimalsCells
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Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. Nature. 2011 May 22; 474(7351):399-402.
Batista LF, Pech MF, Zhong FL, Nguyen HN, Xie KT, Zaug AJ, Crary SM, Choi J, Sebastiano V, Cherry A, Giri N, Wernig M, Alter BP, Cech TR, Savage SA, Reijo Pera RA, Artandi SE. PMID: 21602826; PMCID: PMC3155806.
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PubMed Mentions:
152 Fields:
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HumansCells
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Embryonic stem cells, derived either after in vitro fertilization or nuclear transfer, prolong survival of semiallogeneic heart transplants. J Immunol. 2011 Apr 01; 186(7):4164-74.
Imberti B, Casiraghi F, Cugini D, Azzollini N, Cassis P, Todeschini M, Solini S, Sebastiano V, Zuccotti M, Garagna S, Redi CA, Noris M, Morigi M, Remuzzi G. PMID: 21389254.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Ultrastructural characterization of mouse embryonic stem cell-derived oocytes and granulosa cells. Stem Cells Dev. 2011 Dec; 20(12):2205-15.
Psathaki OE, Hübner K, Sabour D, Sebastiano V, Wu G, Sugawa F, Wieacker P, Pennekamp P, Schöler HR. PMID: 21244227.
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PubMed Mentions:
10 Fields:
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AnimalsCells
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Oct1 regulates trophoblast development during early mouse embryogenesis. Development. 2010 Nov; 137(21):3551-60.
Sebastiano V, Dalvai M, Gentile L, Schubart K, Sutter J, Wu GM, Tapia N, Esch D, Ju JY, Hübner K, Bravo MJ, Schöler HR, Cavaleri F, Matthias P. PMID: 20876643.
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PubMed Mentions:
34 Fields:
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AnimalsCells
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Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes. EMBO J. 2010 Jun 02; 29(11):1877-88.
Wossidlo M, Arand J, Sebastiano V, Lepikhov K, Boiani M, Reinhardt R, Schöler H, Walter J. PMID: 20442707; PMCID: PMC2885932.
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PubMed Mentions:
113 Fields:
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AnimalsCells
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Induction of pluripotency in adult unipotent germline stem cells. Cell Stem Cell. 2009 Jul 02; 5(1):87-96.
Ko K, Tapia N, Wu G, Kim JB, Bravo MJ, Sasse P, Glaser T, Ruau D, Han DW, Greber B, Hausdörfer K, Sebastiano V, Stehling M, Fleischmann BK, Brüstle O, Zenke M, Schöler HR. PMID: 19570517.
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PubMed Mentions:
103 Fields:
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AnimalsCells
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Oct4-induced pluripotency in adult neural stem cells. Cell. 2009 Feb 06; 136(3):411-9.
Kim JB, Sebastiano V, Wu G, Araúzo-Bravo MJ, Sasse P, Gentile L, Ko K, Ruau D, Ehrich M, van den Boom D, Meyer J, Hübner K, Bernemann C, Ortmeier C, Zenke M, Fleischmann BK, Zaehres H, Schöler HR. PMID: 19203577.
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PubMed Mentions:
416 Fields:
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AnimalsCells
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Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature. 2008 Jul 31; 454(7204):646-50.
Kim JB, Zaehres H, Wu G, Gentile L, Ko K, Sebastiano V, Araúzo-Bravo MJ, Ruau D, Han DW, Zenke M, Schöler HR. PMID: 18594515.
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PubMed Mentions:
386 Fields:
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AnimalsCells
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Experimental demonstration that mammalian oocytes are not selective towards X- or Y-bearing sperm. Mol Reprod Dev. 2005 Jun; 71(2):245-6.
Zuccotti M, Sebastiano V, Garagna S, Redi CA. PMID: 15791593.
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PubMed Mentions:
4 Fields:
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AnimalsCells
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Cloned pre-implantation mouse embryos show correct timing but altered levels of gene expression. Mol Reprod Dev. 2005 Feb; 70(2):146-54.
Sebastiano V, Gentile L, Garagna S, Redi CA, Zuccotti M. PMID: 15570622.
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PubMed Mentions:
7 Fields:
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AnimalsCells
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Three-dimensional localization and dynamics of centromeres in mouse oocytes during folliculogenesis. J Mol Histol. 2004 Aug; 35(6):631-8.
Garagna S, Merico V, Sebastiano V, Monti M, Orlandini G, Gatti R, Scandroglio R, Redi CA, Zuccotti M. PMID: 15614617.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Single-cell quantitative RT-PCR analysis of Cpt1b and Cpt2 gene expression in mouse antral oocytes and in preimplantation embryos. Cytogenet Genome Res. 2004; 105(2-4):215-21.
Gentile L, Monti M, Sebastiano V, Merico V, Nicolai R, Calvani M, Garagna S, Redi CA, Zuccotti M. PMID: 15237209.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells