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Zell, Jason Adam

TitleAssociate Professor
InstitutionUniversity of California, Irvine
DepartmentMedicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-5153
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    Collapse Research 
    Collapse Research Activities and Funding
    Risk reduction through polyamine inhibition among colorectal carcinoma patients
    NIH/NCI K23CA133142Aug 20, 2009 - Jul 31, 2013
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Tran PN, Taylor TH, Klempner SJ, Zell JA. The impact of gender, race, socioeconomic status, and treatment on outcomes in esophageal cancer: A population-based analysis. J Carcinog. 2017; 16:3. PMID: 28974922.
      View in: PubMed
    2. Moghadamyeghaneh Z, Alizadeh RF, Phelan M, Carmichael JC, Mills S, Pigazzi A, Zell JA, Stamos MJ. Trends in colorectal cancer admissions and stage at presentation: impact of screening. Surg Endosc. 2016 08; 30(8):3604-10. PMID: 26541735.
      View in: PubMed
    3. Zhang K, Kang DK, Ali MM, Liu L, Labanieh L, Lu M, Riazifar H, Nguyen TN, Zell JA, Digman MA, Gratton E, Li J, Zhao W. Digital quantification of miRNA directly in plasma using integrated comprehensive droplet digital detection. Lab Chip. 2015 Nov 07; 15(21):4217-26. PMID: 26387763; PMCID: PMC4631652 [Available on 11/07/16].
      View in: PubMed, PubMed Central
    4. Zell J, You YN, Boughey JC. PACES trial: Evaluating the effectiveness of eflornithine and sulindac in preventing colon adenomas. Bull Am Coll Surg. 2015 Aug; 100(8):70-1. PMID: 26419059.
      View in: PubMed
    5. Gillen DL, Meyskens FL, Morgan TR, Zell JA, Carroll R, Benya R, Chen WP, Mo A, Tucker C, Bhattacharya A, Huang Z, Arcilla M, Wong V, Chung J, Gonzalez R, Rodriguez LM, Szabo E, Rosenberg DW, Lipkin SM. A phase IIa randomized, double-blind trial of erlotinib in inhibiting epidermal growth factor receptor signaling in aberrant crypt foci of the colorectum. Cancer Prev Res (Phila). 2015 Mar; 8(3):222-30. PMID: 25604134; PMCID: PMC4355051.
      View in: PubMed, PubMed Central
    6. Singh KE, Taylor TH, Pan CG, Stamos MJ, Zell JA. Colorectal Cancer Incidence Among Young Adults in California. J Adolesc Young Adult Oncol. 2014 Dec 01; 3(4):176-184. PMID: 25538862.
      View in: PubMed
    7. Tsang WY, Ziogas A, Lin BS, Seery TE, Karnes W, Stamos MJ, Zell JA. Role of primary tumor resection among chemotherapy-treated patients with synchronous stage IV colorectal cancer: a survival analysis. J Gastrointest Surg. 2014 Mar; 18(3):592-8. PMID: 24297651; PMCID: PMC4035039.
      View in: PubMed, PubMed Central
    8. Subramaniam S, Zell JA, Kunz PL. Everolimus causing severe hypertriglyceridemia and acute pancreatitis. J Natl Compr Canc Netw. 2013 Jan 01; 11(1):5-9. PMID: 23307976.
      View in: PubMed
    9. Seery TE, Ziogas A, Lin BS, Pan CJ, Stamos MJ, Zell JA. Mortality risk after preoperative versus postoperative chemotherapy and radiotherapy in lymph node-positive rectal cancer. J Gastrointest Surg. 2013 Feb; 17(2):374-81. PMID: 23242847; PMCID: PMC3551443.
      View in: PubMed, PubMed Central
    10. Zell JA, Lin BS, Ziogas A, Anton-Culver H. Meat consumption, ornithine decarboxylase gene polymorphism, and outcomes after colorectal cancer diagnosis. J Carcinog. 2012; 11:17. PMID: 23233821; PMCID: PMC3516190.
      View in: PubMed, PubMed Central
    11. Zell JA, Lin BS, Madson N, McLaren CE, Gerner EW, Meyskens FL. Role of obesity in a randomized placebo-controlled trial of difluoromethylornithine (DFMO) + sulindac for the prevention of sporadic colorectal adenomas. Cancer Causes Control. 2012 Oct; 23(10):1739-44. PMID: 22907422; PMCID: PMC3443348.
      View in: PubMed, PubMed Central
    12. Rial NS, Zell JA, Cohen AM, Gerner EW. Clinical end points for developing pharmaceuticals to manage patients with a sporadic or genetic risk of colorectal cancer. Expert Rev Gastroenterol Hepatol. 2012 Aug; 6(4):507-17. PMID: 22928902; PMCID: PMC3587976.
      View in: PubMed, PubMed Central
    13. Masoomi H, Ziogas A, Lin BS, Barleben A, Mills S, Stamos MJ, Zell JA. Population-based evaluation of adenosquamous carcinoma of the colon and rectum. Dis Colon Rectum. 2012 May; 55(5):509-14. PMID: 22513428; PMCID: PMC3330249.
      View in: PubMed, PubMed Central
    14. Lee J, Bhatia NN, Hoang BH, Ziogas A, Zell JA. Analysis of prognostic factors for patients with chordoma with use of the California Cancer Registry. J Bone Joint Surg Am. 2012 Feb 15; 94(4):356-63. PMID: 22336975.
      View in: PubMed
    15. Pan CJ, Ziogas A, Buchberg B, Raj KP, Mills SD, Stamos MJ, Zell JA. Timing of radiation therapy, lymph node retrieval, and survival in rectal cancer. Dis Colon Rectum. 2011 May; 54(5):526-34. PMID: 21471752.
      View in: PubMed
    16. Lipkin S, Lee J, Imagawa D, Hewitt SM, Tucker C, Zell JA, Wong V, Garcia A, Gonzalez R, Della Zanna G, Richmond E, Rodriguez LM, Bigg M, Schnoll-Sussmans F, Meyskens F. Phase IIA trial testing erlotinib as an intervention against intraductal pancreatic mucinous neoplasms. Cancer Prev Res (Phila). 2011 Apr; 4(4):512-3. PMID: 21464031.
      View in: PubMed
    17. Zell JA. Clinical trials update: Tertiary prevention of colorectal cancer. J Carcinog. 2011 Mar 24; 10:8. PMID: 21483656; PMCID: PMC3072658.
      View in: PubMed, PubMed Central
    18. Raj KP, Taylor TH, Wray C, Stamos MJ, Zell JA. Risk of second primary colorectal cancer among colorectal cancer cases: a population-based analysis. J Carcinog. 2011 Mar 17; 10:6. PMID: 21483654; PMCID: PMC3072650.
      View in: PubMed, PubMed Central
    19. Bessonova L, Taylor TH, Mehta RS, Zell JA, Anton-Culver H. Risk of a second breast cancer associated with hormone-receptor and HER2/neu status of the first breast cancer. Cancer Epidemiol Biomarkers Prev. 2011 Feb; 20(2):389-96. PMID: 21217087; PMCID: PMC4110060.
      View in: PubMed, PubMed Central
    20. Katz MH, Taylor TH, Al-Refaie WB, Hanna MH, Imagawa DK, Anton-Culver H, Zell JA. Adenosquamous versus adenocarcinoma of the pancreas: a population-based outcomes analysis. J Gastrointest Surg. 2011 Jan; 15(1):165-74. PMID: 21082275; PMCID: PMC3023036.
      View in: PubMed, PubMed Central
    21. Zell JA, McLaren CE, Chen WP, Thompson PA, Gerner EW, Meyskens FL. Ornithine decarboxylase-1 polymorphism, chemoprevention with eflornithine and sulindac, and outcomes among colorectal adenoma patients. J Natl Cancer Inst. 2010 Oct 06; 102(19):1513-6. PMID: 20798393; PMCID: PMC2950167.
      View in: PubMed, PubMed Central
    22. Ahn MJ, Lee J, Park YH, Ahn JS, Ziogas A, Zell JA, Park K, Ou SH. Korean ethnicity as compared with white ethnicity is an independent favorable prognostic factor for overall survival in non-small cell lung cancer before and after the oral epidermal growth factor receptor tyrosine kinase inhibitor era. J Thorac Oncol. 2010 Aug; 5(8):1185-96. PMID: 20592628.
      View in: PubMed
    23. Kawaguchi T, Matsumura A, Fukai S, Tamura A, Saito R, Zell JA, Maruyama Y, Ziogas A, Kawahara M, Ignatius Ou SH. Japanese ethnicity compared with Caucasian ethnicity and never-smoking status are independent favorable prognostic factors for overall survival in non-small cell lung cancer: a collaborative epidemiologic study of the National Hospital Organization Study Group for Lung Cancer (NHSGLC) in Japan and a Southern California Regional Cancer Registry databases. J Thorac Oncol. 2010 Jul; 5(7):1001-10. PMID: 20526205.
      View in: PubMed
    24. Zell JA, Ziogas A, Bernstein L, Clarke CA, Deapen D, Largent JA, Neuhausen SL, Stram DO, Ursin G, Anton-Culver H. Meat consumption, nonsteroidal anti-inflammatory drug use, and mortality among colorectal cancer patients in the California Teachers Study. Cancer Prev Res (Phila). 2010 Jul; 3(7):865-75. PMID: 20551290; PMCID: PMC2931369.
      View in: PubMed, PubMed Central
    25. Thompson PA, Wertheim BC, Zell JA, Chen WP, McLaren CE, LaFleur BJ, Meyskens FL, Gerner EW. Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma. Gastroenterology. 2010 Sep; 139(3):797-805, 805.e1. PMID: 20538001.
      View in: PubMed
    26. Largent JA, Bernstein L, Horn-Ross PL, Marshall SF, Neuhausen S, Reynolds P, Ursin G, Zell JA, Ziogas A, Anton-Culver H. Hypertension, antihypertensive medication use, and breast cancer risk in the California Teachers Study cohort. Cancer Causes Control. 2010 Oct; 21(10):1615-24. PMID: 20526803; PMCID: PMC2941047.
      View in: PubMed, PubMed Central
    27. Lee J, Hoang BH, Ziogas A, Zell JA. Analysis of prognostic factors in Ewing sarcoma using a population-based cancer registry. Cancer. 2010 Apr 15; 116(8):1964-73. PMID: 20151425.
      View in: PubMed
    28. Ou SH, Ziogas A, Zell JA. Primary signet-ring carcinoma (SRC) of the lung: a population-based epidemiologic study of 262 cases with comparison to adenocarcinoma of the lung. J Thorac Oncol. 2010 Apr; 5(4):420-7. PMID: 20130484.
      View in: PubMed
    29. Ou SH, Ziogas A, Zell JA. A comparison study of clinicopathologic characteristics of Southern California Asian American Non-small Cell Lung Cancer (NSCLC) patients by smoking status. J Thorac Oncol. 2010 Feb; 5(2):158-68. PMID: 20040896.
      View in: PubMed
    30. Zell JA, Ziogas A, Bernstein L, Clarke CA, Deapen D, Largent JA, Neuhausen SL, Stram DO, Ursin G, Anton-Culver H. Nonsteroidal anti-inflammatory drugs: effects on mortality after colorectal cancer diagnosis. Cancer. 2009 Dec 15; 115(24):5662-71. PMID: 19827153; PMCID: PMC3008399.
      View in: PubMed, PubMed Central
    31. Timberlake DS, Zell JA. Review of epidemiologic data on the debate over smokeless tobacco's role in harm reduction. BMC Med. 2009 Oct 19; 7:61. PMID: 19840371; PMCID: PMC2771035.
      View in: PubMed, PubMed Central
    32. Ou SH, Zell JA. Carcinoma NOS is a common histologic diagnosis and is increasing in proportion among non-small cell lung cancer histologies. J Thorac Oncol. 2009 Oct; 4(10):1202-11. PMID: 19701111.
      View in: PubMed
    33. Zell JA, Ziogas A, Ignatenko N, Honda J, Qu N, Bobbs AS, Neuhausen SL, Gerner EW, Anton-Culver H. Associations of a polymorphism in the ornithine decarboxylase gene with colorectal cancer survival. Clin Cancer Res. 2009 Oct 01; 15(19):6208-16. PMID: 19789310; PMCID: PMC2769500.
      View in: PubMed, PubMed Central
    34. Ou SH, Ziogas A, Zell JA. Asian ethnicity is a favorable prognostic factor for overall survival in non-small cell lung cancer (NSCLC) and is independent of smoking status. J Thorac Oncol. 2009 Sep; 4(9):1083-93. PMID: 19652625.
      View in: PubMed
    35. Wray CM, Ziogas A, Hinojosa MW, Le H, Stamos MJ, Zell JA. Tumor subsite location within the colon is prognostic for survival after colon cancer diagnosis. Dis Colon Rectum. 2009 Aug; 52(8):1359-66. PMID: 19617745.
      View in: PubMed
    36. Zell JA, Ignatius Ou SH. Survival prognostication in non-small cell lung cancer. J Thorac Oncol. 2009 Jul; 4(7):785-6. PMID: 19550241.
      View in: PubMed
    37. Ou SI, Zell JA. The effect of tumor size on non-size-based descriptors in staging of stage I non-small cell lung cancer. Chest. 2009 Jun; 135(6):1695-1696. PMID: 19497911.
      View in: PubMed
    38. Raj KP, Sanati H, Mehta RS, Zell JA. Need for a new treatment strategy: leptomeningeal carcinomatosis from gastric cancer. Anticancer Drugs. 2009 Apr; 20(4):301-4. PMID: 19247177.
      View in: PubMed
    39. Zell JA, Pelot D, Chen WP, McLaren CE, Gerner EW, Meyskens FL. Risk of cardiovascular events in a randomized placebo-controlled, double-blind trial of difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas. Cancer Prev Res (Phila). 2009 Mar; 2(3):209-12. PMID: 19258540.
      View in: PubMed
    40. Ignatius Ou SH, Zell JA. The applicability of the proposed IASLC staging revisions to small cell lung cancer (SCLC) with comparison to the current UICC 6th TNM Edition. J Thorac Oncol. 2009 Mar; 4(3):300-10. PMID: 19156001.
      View in: PubMed
    41. Zell JA, Tsang WY, Taylor TH, Mehta RS, Anton-Culver H. Prognostic impact of human epidermal growth factor-like receptor 2 and hormone receptor status in inflammatory breast cancer (IBC): analysis of 2,014 IBC patient cases from the California Cancer Registry. Breast Cancer Res. 2009; 11(1):R9. PMID: 19228416; PMCID: PMC2687713.
      View in: PubMed, PubMed Central
    42. Le H, Ziogas A, Taylor TH, Lipkin SM, Zell JA. Survival of distinct Asian groups among colorectal cancer cases in California. Cancer. 2009 Jan 15; 115(2):259-70. PMID: 19109815; PMCID: PMC4042844.
      View in: PubMed, PubMed Central
    43. Ou SH, Ziogas A, Zell JA. Prognostic factors for survival in extensive stage small cell lung cancer (ED-SCLC): the importance of smoking history, socioeconomic and marital statuses, and ethnicity. J Thorac Oncol. 2009 Jan; 4(1):37-43. PMID: 19096304.
      View in: PubMed
    44. Zell JA, Honda J, Ziogas A, Anton-Culver H. Survival after colorectal cancer diagnosis is associated with colorectal cancer family history. Cancer Epidemiol Biomarkers Prev. 2008 Nov; 17(11):3134-40. PMID: 18990755; PMCID: PMC2739671.
      View in: PubMed, PubMed Central
    45. Le H, Ziogas A, Rhee JM, Lee JG, Lipkin SM, Zell JA. A population-based, descriptive analysis of malignant intraductal papillary mucinous neoplasms of the pancreas. Cancer Epidemiol Biomarkers Prev. 2008 Oct; 17(10):2737-41. PMID: 18843017.
      View in: PubMed
    46. Ou SH, Zell JA. Prognostic significance of the number of lymph nodes removed at lobectomy in stage IA non-small cell lung cancer. J Thorac Oncol. 2008 Aug; 3(8):880-6. PMID: 18670306.
      View in: PubMed
    47. Le H, Ziogas A, Lipkin SM, Zell JA. Effects of socioeconomic status and treatment disparities in colorectal cancer survival. Cancer Epidemiol Biomarkers Prev. 2008 Aug; 17(8):1950-62. PMID: 18708384.
      View in: PubMed
    48. Narasimhan M, Rose R, Ramakrishnan R, Zell JA, Rathinavelu A. Identification of HDM2 as a regulator of VEGF expression in cancer cells. Life Sci. 2008 Jun 20; 82(25-26):1231-41. PMID: 18504050.
      View in: PubMed
    49. Ou SH, Zell JA, Ziogas A, Anton-Culver H. Low socioeconomic status is a poor prognostic factor for survival in stage I nonsmall cell lung cancer and is independent of surgical treatment, race, and marital status. Cancer. 2008 May 01; 112(9):2011-20. PMID: 18361399.
      View in: PubMed
    50. Ou SH, Zell JA. Validation study of the proposed IASLC staging revisions of the T4 and M non-small cell lung cancer descriptors using data from 23,583 patients in the California Cancer Registry. J Thorac Oncol. 2008 Mar; 3(3):216-27. PMID: 18317063.
      View in: PubMed
    51. Zell JA, Ou SH, Ziogas A, Anton-Culver H. Survival improvements for advanced stage nonbronchioloalveolar carcinoma-type nonsmall cell lung cancer cases with ipsilateral intrapulmonary nodules. Cancer. 2008 Jan 01; 112(1):136-43. PMID: 17960795.
      View in: PubMed
    52. Zell JA, Cinar P, Mobasher M, Ziogas A, Meyskens FL, Anton-Culver H. Survival for patients with invasive cutaneous melanoma among ethnic groups: the effects of socioeconomic status and treatment. J Clin Oncol. 2008 Jan 01; 26(1):66-75. PMID: 18165642.
      View in: PubMed
    53. Zell JA, Ignatius Ou SH, Ziogas A, Anton-Culver H. Validation of the proposed International Association for the Study of Lung Cancer non-small cell lung cancer staging system revisions for advanced bronchioloalveolar carcinoma using data from the California Cancer Registry. J Thorac Oncol. 2007 Dec; 2(12):1078-85. PMID: 18090578.
      View in: PubMed
    54. Ou SH, Zell JA, Ziogas A, Anton-Culver H. Prognostic significance of the non-size-based AJCC T2 descriptors: visceral pleura invasion, hilar atelectasis, or obstructive pneumonitis in stage IB non-small cell lung cancer is dependent on tumor size. Chest. 2008 Mar; 133(3):662-9. PMID: 17925418.
      View in: PubMed
    55. Ou SH, Zell JA, Ziogas A, Anton-Culver H. Prognostic factors for survival of stage I nonsmall cell lung cancer patients : a population-based analysis of 19,702 stage I patients in the California Cancer Registry from 1989 to 2003. Cancer. 2007 Oct 01; 110(7):1532-41. PMID: 17702091.
      View in: PubMed
    56. Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM. Natural history of stage I non-small cell lung cancer: implications for early detection. Chest. 2007 Jul; 132(1):193-9. PMID: 17505036.
      View in: PubMed
    57. Zell JA, Rhee JM, Ziogas A, Lipkin SM, Anton-Culver H. Race, socioeconomic status, treatment, and survival time among pancreatic cancer cases in California. Cancer Epidemiol Biomarkers Prev. 2007 Mar; 16(3):546-52. PMID: 17372250.
      View in: PubMed
    58. Zell JA, Ignatenko NA, Yerushalmi HF, Ziogas A, Besselsen DG, Gerner EW, Anton-Culver H. Risk and risk reduction involving arginine intake and meat consumption in colorectal tumorigenesis and survival. Int J Cancer. 2007 Feb 01; 120(3):459-68. PMID: 17096347.
      View in: PubMed
    59. Zell JA, McEligot AJ, Ziogas A, Holcombe RF, Anton-Culver H. Differential effects of wine consumption on colorectal cancer outcomes based on family history of the disease. Nutr Cancer. 2007; 59(1):36-45. PMID: 17927500.
      View in: PubMed
    60. Raz DJ, Zell JA, Karnezis AN, Odisho A, Ignatius Ou SH, Anton-Culver H, Jablons DM. Misclassification of bronchioloalveolar carcinoma with cytologic diagnosis of lung cancer. J Thorac Oncol. 2006 Nov; 1(9):943-8. PMID: 17409976.
      View in: PubMed
    61. Zell JA, Iyer PR, Kukes GD, Beamon DB. An unusual case of renal carcinoma. Pathology. 2006 Aug; 38(4):370-1. PMID: 16916734.
      View in: PubMed
    62. Zell JA, Ou SH, Ziogas A, Anton-Culver H. Long-term survival differences for bronchiolo-alveolar carcinoma patients with ipsilateral intrapulmonary metastasis at diagnosis. Ann Oncol. 2006 Aug; 17(8):1255-62. PMID: 16766595.
      View in: PubMed
    63. Zell JA, Ou SH, Ziogas A, Anton-Culver H. Epidemiology of bronchioloalveolar carcinoma: improvement in survival after release of the 1999 WHO classification of lung tumors. J Clin Oncol. 2005 Nov 20; 23(33):8396-405. PMID: 16293870.
      View in: PubMed
    64. Bokhari SW, Bokhari ZW, Zell JA, Lee DW, Faxon DP. Plasma homocysteine levels and the left ventricular systolic function in coronary artery disease patients. Coron Artery Dis. 2005 May; 16(3):153-61. PMID: 15818084.
      View in: PubMed
    65. Zell JA, Chang JC. Neoplastic fever: a neglected paraneoplastic syndrome. Support Care Cancer. 2005 Nov; 13(11):870-7. PMID: 15864658.
      View in: PubMed
    66. Zell JA, Yoon EJ, Ignatius Ou SH, Hoefs JC, Chang JC. Precore mutant hepatitis B reactivation after treatment with CHOP-rituximab. Anticancer Drugs. 2005 Jan; 16(1):83-5. PMID: 15613909.
      View in: PubMed
    67. Canetti M, Akhter MW, Lerman A, Karaalp IS, Zell JA, Singh H, Mehra A, Elkayam U. Evaluation of myocardial blood flow reserve in patients with chronic congestive heart failure due to idiopathic dilated cardiomyopathy. Am J Cardiol. 2003 Nov 15; 92(10):1246-9. PMID: 14609613.
      View in: PubMed
    68. Zell JA, Ramakrishnan R, Rathinavelu A. Regulation of mdm2 mRNA expression in human breast tumor-derived GI-101A cells. Life Sci. 2002 Oct 04; 71(20):2331-9. PMID: 12231395.
      View in: PubMed
    69. O'Rourke A, Zell JA, Varkey-Zell TT, Barone JL, Bayona M. Laparoscopic diagnosis and repair of asymptomatic bilateral inguinal hernias. Am J Surg. 2002 Jan; 183(1):15-9. PMID: 11869696.
      View in: PubMed
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