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A Low-Cost Modular Imaging System for Rapid, Multiplexed Immunofluorescence Detection in Clinical Tissues. Int J Mol Sci. 2023 Apr 10; 24(8).
Gu J, Jian H, Wei C, Shiu J, Ganesan A, Zhao W, Hedde PN. PMID: 37108170; PMCID: PMC10138925.
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PubMed Mentions: Fields:
Translation:
Humans
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Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer. J Med Chem. 2023 Apr 07.
Brindani N, Vuong LM, Acquistapace IM, La Serra MA, Ortega JA, Veronesi M, Bertozzi SM, Summa M, Girotto S, Bertorelli R, Armirotti A, Ganesan AK, De Vivo M. PMID: 37026468.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Efficacy and safety of oral ritlecitinib for the treatment of active nonsegmental vitiligo: A randomized phase 2b clinical trial. J Am Acad Dermatol. 2023 02; 88(2):395-403.
Ezzedine K, Peeva E, Yamaguchi Y, Cox LA, Banerjee A, Han G, Hamzavi I, Ganesan AK, Picardo M, Thaçi D, Harris JE, Bae JM, Tsukamoto K, Sinclair R, Pandya AG, Sloan A, Yu D, Gandhi K, Vincent MS, King B. PMID: 36370907.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Association of vulvar lichen sclerosus with endometrial and ovarian cancer. JAAD Int. 2022 Dec; 9:26-27.
Ganesan AK, Taylor TH, Kraus CN. PMID: 36034745; PMCID: PMC9411685.
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PubMed Mentions:
2
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Multimodal analyses of vitiligo skin identify tissue characteristics of stable disease. JCI Insight. 2022 07 08; 7(13).
Shiu J, Zhang L, Lentsch G, Flesher JL, Jin S, Polleys C, Jo SJ, Mizzoni C, Mobasher P, Kwan J, Rius-Diaz F, Tromberg BJ, Georgakoudi I, Nie Q, Balu M, Ganesan AK. PMID: 35653192; PMCID: PMC9310536.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Alchemical Free Energy Calculations to Investigate Protein-Protein Interactions: the Case of the CDC42/PAK1 Complex. J Chem Inf Model. 2022 06 27; 62(12):3023-3033.
La Serra MA, Vidossich P, Acquistapace I, Ganesan AK, De Vivo M. PMID: 35679463; PMCID: PMC9241073.
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PubMed Mentions:
3 Fields:
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Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer. Cell Rep. 2022 Apr 26; 39(4):110760.
Jahid S, Ortega JA, Vuong LM, Acquistapace IM, Hachey SJ, Flesher JL, La Serra MA, Brindani N, La Sala G, Manigrasso J, Arencibia JM, Bertozzi SM, Summa M, Bertorelli R, Armirotti A, Jin R, Liu Z, Chen CF, Edwards R, Hughes CCW, De Vivo M, Ganesan AK. PMID: 35476990; PMCID: PMC9128537.
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PubMed Mentions: Fields:
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Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer. Cell Rep. 2022 04 05; 39(1):110641.
Jahid S, Ortega JA, Vuong LM, Acquistapace IM, Hachey SJ, Flesher JL, La Serra MA, Brindani N, La Sala G, Manigrasso J, Arencibia JM, Bertozzi SM, Summa M, Bertorelli R, Armirotti A, Jin R, Liu Z, Chen CF, Edwards R, Hughes CCW, De Vivo M, Ganesan AK. PMID: 35385746; PMCID: PMC9127750.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Spatial transcriptomics using combinatorial fluorescence spectral and lifetime encoding, imaging and analysis. Nat Commun. 2022 01 10; 13(1):169.
Vu T, Vallmitjana A, Gu J, La K, Xu Q, Flores J, Zimak J, Shiu J, Hosohama L, Wu J, Douglas C, Waterman ML, Ganesan A, Hedde PN, Gratton E, Zhao W. PMID: 35013281; PMCID: PMC8748653.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Comparing the Efficacy of 2 Different Harvesting Techniques for Melanocyte Keratinocyte Transplantation in Vitiligo. Dermatol Surg. 2021 05 01; 47(5):732-733.
Mobasher P, Shiu J, Lentsch G, Ganesan AK. PMID: 33905400.
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PubMed Mentions:
1 Fields:
Translation:
HumansCellsCTClinical Trials
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Fast, large area multiphoton exoscope (FLAME) for macroscopic imaging with microscopic resolution of human skin. Sci Rep. 2020 10 22; 10(1):18093.
Fast A, Lal A, Durkin AF, Lentsch G, Harris RM, Zachary CB, Ganesan AK, Balu M. PMID: 33093610; PMCID: PMC7582965.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes. Elife. 2020 10 13; 9.
Ruiz-Vega R, Chen CF, Razzak E, Vasudeva P, Krasieva TB, Shiu J, Caldwell MG, Yan H, Lowengrub J, Ganesan AK, Lander AD. PMID: 33047672; PMCID: PMC7553774.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Publisher Correction: Transcriptomic and proteomic signatures of stemness and differentiation in the colon crypt. Commun Biol. 2020 Sep 03; 3(1):495.
Habowski AN, Flesher JL, Bates JM, Tsai CF, Martin K, Zhao R, Ganesan AK, Edwards RA, Shi T, Wiley HS, Shi Y, Hertel KJ, Waterman ML. PMID: 32884070; PMCID: PMC7471919.
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Transcriptomic and proteomic signatures of stemness and differentiation in the colon crypt. Commun Biol. 2020 08 19; 3(1):453.
Habowski AN, Flesher JL, Bates JM, Tsai CF, Martin K, Zhao R, Ganesan AK, Edwards RA, Shi T, Wiley HS, Shi Y, Hertel KJ, Waterman ML. PMID: 32814826; PMCID: PMC7438495.
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PubMed Mentions:
15 Translation:
AnimalsCells
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Non-invasive optical biopsy by multiphoton microscopy identifies the live morphology of common melanocytic nevi. Pigment Cell Melanoma Res. 2020 11; 33(6):869-877.
Lentsch G, Valdebran M, Saknite I, Smith J, Linden KG, König K, Barr RJ, Harris RM, Tromberg BJ, Ganesan AK, Zachary CB, Kelly KM, Balu M. PMID: 32485062; PMCID: PMC7687135.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Gene mutations distinguishing gastric from colorectal and esophageal adenocarcinomas. J Gastrointest Oncol. 2020 Feb; 11(1):45-54.
Hoang T, Ganesan AK, Hiyama D, Dayyani F. PMID: 32175104; PMCID: PMC7052769.
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PubMed Mentions:
1
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Open-label pilot study of tofacitinib 2% for the treatment of refractory vitiligo. Br J Dermatol. 2020 04; 182(4):1047-1049.
Mobasher P, Guerra R, Li SJ, Frangos J, Ganesan AK, Huang V. PMID: 31605536; PMCID: PMC7124977.
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PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
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Delineating the role of MITF isoforms in pigmentation and tissue homeostasis. Pigment Cell Melanoma Res. 2020 03; 33(2):279-292.
Flesher JL, Paterson-Coleman EK, Vasudeva P, Ruiz-Vega R, Marshall M, Pearlman E, MacGregor GR, Neumann J, Ganesan AK. PMID: 31562697; PMCID: PMC7822220.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Real-world experience of dupilumab treatment for atopic dermatitis in adults: a retrospective analysis of patients' records. Int J Dermatol. 2020 Feb; 59(2):253-256.
Wang C, Kraus CN, Patel KG, Ganesan AK, Grando SA. PMID: 31286499.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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In vivo multiphoton microscopy of melasma. Pigment Cell Melanoma Res. 2019 05; 32(3):403-411.
Lentsch G, Balu M, Williams J, Lee S, Harris RM, König K, Ganesan A, Tromberg BJ, Nair N, Santhanam U, Misra M. PMID: 30506627; PMCID: PMC6483848.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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PIKfyve regulates melanosome biogenesis. PLoS Genet. 2018 03; 14(3):e1007290.
Liggins MC, Flesher JL, Jahid S, Vasudeva P, Eby V, Takasuga S, Sasaki J, Sasaki T, Boissy RE, Ganesan AK. PMID: 29584722; PMCID: PMC5889185.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Intramuscular Steroids in the Treatment of Dermatologic Disease: A Systematic Review. J Drugs Dermatol. 2018 03 01; 17(3):323-329.
Thomas LW, Elsensohn A, Bergheim T, Shiu J, Ganesan A. PMID: 29537450.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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The RhoJ-BAD signaling network: An Achilles' heel for BRAF mutant melanomas. PLoS Genet. 2017 Jul; 13(7):e1006913.
Ruiz R, Jahid S, Harris M, Marzese DM, Espitia F, Vasudeva P, Chen CF, de Feraudy S, Wu J, Gillen DL, Krasieva TB, Tromberg BJ, Pavan WJ, Hoon DS, Ganesan AK. PMID: 28753606; PMCID: PMC5549996.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Pharmacophore Identification and Scaffold Exploration to Discover Novel, Potent, and Chemically Stable Inhibitors of Acid Ceramidase in Melanoma Cells. J Med Chem. 2017 07 13; 60(13):5800-5815.
Ortega JA, Arencibia JM, La Sala G, Borgogno M, Bauer I, Bono L, Braccia C, Armirotti A, Girotto S, Ganesan A, De Vivo M. PMID: 28603987.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment. Cell Rep. 2017 03 07; 18(10):2331-2342.
Chen CF, Ruiz-Vega R, Vasudeva P, Espitia F, Krasieva TB, de Feraudy S, Tromberg BJ, Huang S, Garner CP, Wu J, Hoon DS, Ganesan AK. PMID: 28273450; PMCID: PMC5393360.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Pigment Production Analysis in Human Melanoma Cells. Methods Mol Biol. 2016 May 25.
Hopkin AS, Paterson EK, Ruiz R, Ganesan AK. PMID: 27221340.
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PubMed Mentions:
1 Fields:
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222.
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, et al. PMID: 26799652; PMCID: PMC4835977.
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PubMed Mentions:
2703 Fields:
Translation:
HumansAnimals
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Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle. PLoS One. 2015; 10(11):e0143702.
Paterson EK, Fielder TJ, MacGregor GR, Ito S, Wakamatsu K, Gillen DL, Eby V, Boissy RE, Ganesan AK. PMID: 26619124; PMCID: PMC4664286.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION. J Biol Chem. 2016 Jan 29; 291(5):2422-34.
Realini N, Palese F, Pizzirani D, Pontis S, Basit A, Bach A, Ganesan A, Piomelli D. PMID: 26553872; PMCID: PMC4732224.
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PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Treating hyperpigmentation in darker-skinned patients. J Drugs Dermatol. 2013 May; 12(5):563-7.
Saedi N, Ganesan AK. PMID: 23652952.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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9-cis retinoic acid is the ALDH1A1 product that stimulates melanogenesis. Exp Dermatol. 2013 Mar; 22(3):202-9.
Paterson EK, Ho H, Kapadia R, Ganesan AK. PMID: 23489423; PMCID: PMC3602921.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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RhoJ modulates melanoma invasion by altering actin cytoskeletal dynamics. Pigment Cell Melanoma Res. 2013 Mar; 26(2):218-25.
Ho H, Soto Hopkin A, Kapadia R, Vasudeva P, Schilling J, Ganesan AK. PMID: 23253891; PMCID: PMC4528913.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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RhoJ regulates melanoma chemoresistance by suppressing pathways that sense DNA damage. Cancer Res. 2012 Nov 01; 72(21):5516-28.
Ho H, Aruri J, Kapadia R, Mehr H, White MA, Ganesan AK. PMID: 22971344; PMCID: PMC3548429.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Chemical leukoderma after the application of a transdermal methylphenidate patch. J Am Acad Dermatol. 2012 Jun; 66(6):e237-8.
Ghasri P, Gattu S, Saedi N, Ganesan AK. PMID: 22583724; PMCID: PMC3354955.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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The pleiotropic roles of autophagy regulators in melanogenesis. Pigment Cell Melanoma Res. 2011 Aug; 24(4):595-604.
Ho H, Ganesan AK. PMID: 21777401.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition. J Biol Chem. 2011 Apr 08; 286(14):12509-23.
Ho H, Kapadia R, Al-Tahan S, Ahmad S, Ganesan AK. PMID: 21317285; PMCID: PMC3069453.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Protein interaction network topology uncovers melanogenesis regulatory network components within functional genomics datasets. BMC Syst Biol. 2010 Jun 15; 4:84.
Ho H, Milenkovic T, Memisevic V, Aruri J, Przulj N, Ganesan AK. PMID: 20550706; PMCID: PMC2904735.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Systems-level cancer gene identification from protein interaction network topology applied to melanogenesis-related functional genomics data. J R Soc Interface. 2010 Mar 06; 7(44):423-37.
Milenkovic T, Memisevic V, Ganesan AK, Przulj N. PMID: 19625303; PMCID: PMC2842789.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells. PLoS Genet. 2008 Dec; 4(12):e1000298.
Ganesan AK, Ho H, Bodemann B, Petersen S, Aruri J, Koshy S, Richardson Z, Le LQ, Krasieva T, Roth MG, Farmer P, White MA. PMID: 19057677; PMCID: PMC2585813.
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PubMed Mentions:
72 Fields:
Translation:
HumansAnimalsCells
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Broad spectrum identification of SUMO substrates in melanoma cells. Proteomics. 2007 Jun; 7(13):2216-21.
Ganesan AK, Kho Y, Kim SC, Chen Y, Zhao Y, White MA. PMID: 17549794.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Two modes of ligand binding in maltose-binding protein of Escherichia coli. Functional significance in active transport. J Biol Chem. 1997 Jul 11; 272(28):17615-22.
Hall JA, Ganesan AK, Chen J, Nikaido H. PMID: 9211910.
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PubMed Mentions:
21 Fields:
Translation:
Cells