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Wendy F. Liu

Title(s)Associate Professor, Biomedical Engineering
Phone(949) 824-1682
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    Collapse Research 
    Collapse Research Activities and Funding
    Epigenetic regulation of macrophage response to biomaterial implants
    NIH/NIBIB R21EB027840Apr 18, 2019 - Jan 31, 2021
    Role: Co-Principal Investigator
    Mechanochemical regulation of macrophages by the extracellular matrix during wound healing
    NIH/NIAID R21AI128519Jun 1, 2017 - May 31, 2019
    Role: Principal Investigator
    Engineering Biomaterials to Exert Molecular Control of Immune Cell Function
    NIH/NIDCR DP2DE023319Sep 30, 2012 - Aug 31, 2017
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hsieh JY, Keating MT, Smith TD, Meli VS, Botvinick EL, Liu WF. Matrix crosslinking enhances macrophage adhesion, migration, and inflammatory activation. APL Bioeng. 2019 Mar; 3(1):016103. PMID: 31069336.
      View in: PubMed
    2. Meli VS, Veerasubramanian PK, Atcha H, Reitz Z, Downing TL, Liu WF. Biophysical regulation of macrophages in health and disease. J Leukoc Biol. 2019 Mar 12. PMID: 30861205.
      View in: PubMed
    3. Rowley AT, Nagalla RR, Wang SW, Liu WF. Extracellular Matrix-Based Strategies for Immunomodulatory Biomaterials Engineering. Adv Healthc Mater. 2019 Feb 04; e1801578. PMID: 30714328.
      View in: PubMed
    4. Herrera V, Hsu SJ, Rahim MK, Chen C, Nguyen L, Liu WF, Haun JB. Pushing the limits of detection for proteins secreted from single cells using quantum dots. Analyst. 2019 Jan 28; 144(3):980-989. PMID: 30270391.
      View in: PubMed
    5. Liu WF. Control by cell size. Nat Mater. 2018 Dec; 17(12):1055-1056. PMID: 30470831.
      View in: PubMed
    6. Atcha H, Davis CT, Sullivan NR, Smith TD, Anis S, Dahbour WZ, Robinson ZR, Grosberg A, Liu WF. A Low-Cost Mechanical Stretching Device for Uniaxial Strain of Cells: A Platform for Pedagogy in Mechanobiology. J Biomech Eng. 2018 Aug 01; 140(8). PMID: 30003248.
      View in: PubMed
    7. Kim YK, Chu SH, Hsieh JY, Kamoku CM, Tenner AJ, Liu WF, Wang SW. Incorporation of a Ligand Peptide for Immune Inhibitory Receptor LAIR-1 on Biomaterial Surfaces Inhibits Macrophage Inflammatory Responses. Adv Healthc Mater. 2017 Dec; 6(24). PMID: 29083540.
      View in: PubMed
    8. Smith TD, Nagalla RR, Chen EY, Liu WF. Harnessing macrophage plasticity for tissue regeneration. Adv Drug Deliv Rev. 2017 05 15; 114:193-205. PMID: 28449872.
      View in: PubMed
    9. Hsieh JY, Smith TD, Meli VS, Tran TN, Botvinick EL, Liu WF. Differential regulation of macrophage inflammatory activation by fibrin and fibrinogen. Acta Biomater. 2017 01 01; 47:14-24. PMID: 27662809.
      View in: PubMed
    10. Smith TD, Tse MJ, Read EL, Liu WF. Regulation of macrophage polarization and plasticity by complex activation signals. Integr Biol (Camb). 2016 09 12; 8(9):946-55. PMID: 27492191.
      View in: PubMed
    11. McWhorter FY, Smith TD, Luu TU, Rahim MK, Haun JB, Liu WF. Macrophage secretion heterogeneity in engineered microenvironments revealed using a microwell platform. Integr Biol (Camb). 2016 07 11; 8(7):751-60. PMID: 27291691.
      View in: PubMed
    12. Alfonso-GarcĂ­a A, Smith TD, Datta R, Luu TU, Gratton E, Potma EO, Liu WF. Label-free identification of macrophage phenotype by fluorescence lifetime imaging microscopy. J Biomed Opt. 2016 Apr 30; 21(4):46005. PMID: 27086689.
      View in: PubMed
    13. Wang T, Luu TU, Chen A, Khine M, Liu WF. Topographical modulation of macrophage phenotype by shrink-film multi-scale wrinkles. Biomater Sci. 2016 Jun 24; 4(6):948-52. PMID: 27125253.
      View in: PubMed
    14. Luu TU, Gott SC, Woo BW, Rao MP, Liu WF. Micro- and Nanopatterned Topographical Cues for Regulating Macrophage Cell Shape and Phenotype. ACS Appl Mater Interfaces. 2015 Dec 30; 7(51):28665-72. PMID: 26605491.
      View in: PubMed
    15. McWhorter FY, Davis CT, Liu WF. Physical and mechanical regulation of macrophage phenotype and function. Cell Mol Life Sci. 2015 Apr; 72(7):1303-16. PMID: 25504084.
      View in: PubMed
    16. Kim YK, Que R, Wang SW, Liu WF. Modification of biomaterials with a self-protein inhibits the macrophage response. Adv Healthc Mater. 2014 Jul; 3(7):989-94. PMID: 24573988.
      View in: PubMed
    17. Ueno N, Harker KS, Clarke EV, McWhorter FY, Liu WF, Tenner AJ, Lodoen MB. Real-time imaging of Toxoplasma-infected human monocytes under fluidic shear stress reveals rapid translocation of intracellular parasites across endothelial barriers. Cell Microbiol. 2014 Apr; 16(4):580-95. PMID: 24245749; PMCID: PMC4141879.
    18. McWhorter FY, Wang T, Nguyen P, Chung T, Liu WF. Modulation of macrophage phenotype by cell shape. Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43):17253-8. PMID: 24101477.
      View in: PubMed
    19. Alavi SH, Liu WF, Kheradvar A. Inflammatory response assessment of a hybrid tissue-engineered heart valve leaflet. Ann Biomed Eng. 2013 Feb; 41(2):316-26. PMID: 23053298.
      View in: PubMed
    20. Liu WF. Mechanical regulation of cellular phenotype: implications for vascular tissue regeneration. Cardiovasc Res. 2012 Jul 15; 95(2):215-22. PMID: 22628449.
      View in: PubMed