Olivier Cinquin

Title(s)Associate Professor, Developmental & Cell Biology
SchoolSchool of Biological Sciences
Address4203 McGaugh Hall
Zot 2300
Irvine CA 92697
Phone(949) 257-2819
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    Collapse Research 
    Collapse Research Activities and Funding
    Control of cell cycling speed to delay the onset of senescence
    NIH R01GM102635Aug 20, 2012 - Jul 31, 2018
    Role: Principal Investigator
    Direct tests of the role of stem cells in minimizing mutation accumulation
    NIH R21AG042125Apr 1, 2012 - Mar 31, 2015
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. ChIP-GPT: a managed large language model for robust data extraction from biomedical database records. Brief Bioinform. 2024 Jan 22; 25(2). Cinquin O. PMID: 38314912; PMCID: PMC10840379.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Flexizyme-aminoacylated shortened tRNAs demonstrate that only the aminoacylated acceptor arms of the two tRNA substrates are required for cyclodipeptide synthase activity. Nucleic Acids Res. 2020 11 18; 48(20):11615-11625. Canu N, Tellier C, Babin M, Thai R, Ajel I, Seguin J, Cinquin O, Vinck R, Moutiez M, Belin P, Cintrat JC, Gondry M. PMID: 33095883; PMCID: PMC7672478.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    3. More than just a pool. Elife. 2020 09 11; 9. Cinquin A, Cinquin O. PMID: 32915135; PMCID: PMC7486116.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Gene Expression Noise Enhances Robust Organization of the Early Mammalian Blastocyst. PLoS Comput Biol. 2017 01; 13(1):e1005320. Holmes WR, Reyes de Mochel NS, Wang Q, Du H, Peng T, Chiang M, Cinquin O, Cho K, Nie Q. PMID: 28114387; PMCID: PMC5293272.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    5. Quantification of in vivo progenitor mutation accrual with ultra-low error rate and minimal input DNA using SIP-HAVA-seq. Genome Res. 2016 11; 26(11):1600-1611. Taylor PH, Cinquin A, Cinquin O. PMID: 27803194; PMCID: PMC5088601.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    6. Intermittent Stem Cell Cycling Balances Self-Renewal and Senescence of the C. elegans Germ Line. PLoS Genet. 2016 Apr; 12(4):e1005985. Cinquin A, Chiang M, Paz A, Hallman S, Yuan O, Vysniauskaite I, Fowlkes CC, Cinquin O. PMID: 27077385; PMCID: PMC4831802.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    7. Analysis of in vivo single cell behavior by high throughput, human-in-the-loop segmentation of three-dimensional images. BMC Bioinformatics. 2015 Nov 25; 16:397. Chiang M, Hallman S, Cinquin A, de Mochel NR, Paz A, Kawauchi S, Calof AL, Cho KW, Fowlkes CC, Cinquin O. PMID: 26607933; PMCID: PMC4659165.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    8. Semi-permeable Diffusion Barriers Enhance Patterning Robustness in the C. elegans Germline. Dev Cell. 2015 Nov 23; 35(4):405-17. Cinquin A, Zheng L, Taylor PH, Paz A, Zhang L, Chiang M, Snow JJ, Nie Q, Cinquin O. PMID: 26609956; PMCID: PMC4694723.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    9. POPE: post optimization posterior evaluation of likelihood free models. BMC Bioinformatics. 2015 Aug 20; 16:264. Meeds E, Chiang M, Lee M, Cinquin O, Lowengrub J, Welling M. PMID: 26289041; PMCID: PMC4545973.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Control of Caenorhabditis elegans germ-line stem-cell cycling speed meets requirements of design to minimize mutation accumulation. BMC Biol. 2015 Jul 18; 13:51. Chiang M, Cinquin A, Paz A, Meeds E, Price CA, Welling M, Cinquin O. PMID: 26187634; PMCID: PMC4538916.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    11. BMP signaling is required for cell cleavage in preimplantation-mouse embryos. Dev Biol. 2015 Jan 01; 397(1):45-55. Reyes de Mochel NS, Luong M, Chiang M, Javier AL, Luu E, Toshihiko F, MacGregor GR, Cinquin O, Cho KW. PMID: 25446538; PMCID: PMC4309750.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    12. Live imaging reveals active infiltration of mitotic zone by its stem cell niche. Integr Biol (Camb). 2013 Jul 24; 5(7):976-82. Wong BG, Paz A, Corrado MA, Ramos BR, Cinquin A, Cinquin O, Hui EE. PMID: 23695198; PMCID: PMC3708607.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    13. Phasor approach to fluorescence lifetime microscopy distinguishes different metabolic states of germ cells in a live tissue. Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33):13582-7. Stringari C, Cinquin A, Cinquin O, Digman MA, Donovan PJ, Gratton E. PMID: 21808026; PMCID: PMC3158156.
      View in: PubMed   Mentions: 193     Fields:    Translation:AnimalsCells
    14. Progression from a stem cell-like state to early differentiation in the C. elegans germ line. Proc Natl Acad Sci U S A. 2010 Feb 02; 107(5):2048-53. Cinquin O, Crittenden SL, Morgan DE, Kimble J. PMID: 20080700; PMCID: PMC2836686.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    15. Purpose and regulation of stem cells: a systems-biology view from the Caenorhabditis elegans germ line. J Pathol. 2009 Jan; 217(2):186-98. Cinquin O. PMID: 19065622; PMCID: PMC2929242.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    16. Understanding the somitogenesis clock: what's missing? Mech Dev. 2007 Aug; 124(7-8):501-17. Cinquin O. PMID: 17643270.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    17. A new method to transfect the hypoblast of the chick embryo reveals conservation of the regulation of an Otx2 enhancer between mouse and chick extraembryonic endoderm. BMC Dev Biol. 2007 Apr 02; 7:25. Albazerchi A, Cinquin O, Stern CD. PMID: 17407554; PMCID: PMC1852305.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    18. Repressor dimerization in the zebrafish somitogenesis clock. PLoS Comput Biol. 2007 Feb 16; 3(2):e32. Cinquin O. PMID: 17305423; PMCID: PMC1797823.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    19. Generalized, switch-like competitive heterodimerization networks. Bull Math Biol. 2007 Feb; 69(2):483-94. Cinquin O, Page KM. PMID: 17216403.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    20. Fast-tracking morphogen diffusion. J Theor Biol. 2006 Feb 07; 238(3):532-40. Cinquin O. PMID: 16095625.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    21. High-dimensional switches and the modelling of cellular differentiation. J Theor Biol. 2005 Apr 07; 233(3):391-411. Cinquin O, Demongeot J. PMID: 15652148.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    22. Cloning and expression of malarial pyrimidine enzymes. Nucleosides Nucleotides Nucleic Acids. 2004 Oct; 23(8-9):1459-65. Christopherson RI, Cinquin O, Shojaei M, Kuehn D, Menz RI. PMID: 15571277.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    23. Is the somitogenesis clock really cell-autonomous? A coupled-oscillator model of segmentation. J Theor Biol. 2003 Oct 21; 224(4):459-68. Cinquin O. PMID: 12957118.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    24. Roles of positive and negative feedback in biological systems. C R Biol. 2002 Nov; 325(11):1085-95. Cinquin O, Demongeot J. PMID: 12506722.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    25. Positive and negative feedback: striking a balance between necessary antagonists. J Theor Biol. 2002 May 21; 216(2):229-41. Cinquin O, Demongeot J. PMID: 12079373.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    26. A hybrid plasmid for expression of toxic malarial proteins in Escherichia coli. Mol Biochem Parasitol. 2001 Oct; 117(2):245-7. Cinquin O, Christopherson RI, Menz RI. PMID: 11606237.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
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