 Edwards, Robert A
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| Title | Associate Clinical Professor |
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| Institution | University of California, Irvine |
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| Department | Pathology |
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| Address | 1001 Health Sciences Road
CA 92697-3950
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| Phone | (949) 824-8576 |
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| vCard | Download vCard |
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 Research Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Lee M, Chen GT, Puttock E, Wang K, Edwards R, Waterman ML, Lowengrub J. Mathematical modeling links Wnt signaling to emergent patterns of metabolism in colon cancer. Mol Syst Biol. 2017 02 09; 13(2):912. PMID: 28183841.
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Sprowl-Tanio S, Habowski AN, Pate KT, McQuade MM, Wang K, Edwards R, Grun F, Lyou Y, Waterman ML. Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer. Cancer Metab. 2016; 4:20. PMID: 27729975.
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Pate KT, Stringari C, Sprowl-Tanio S, Wang K, TeSlaa T, Hoverter NP, McQuade MM, Garner C, Digman MA, Teitell MA, Edwards R, Gratton E, Waterman ML. Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer. EMBO J. 2014 Jul 01; 33(13):1454-73. PMID: 24825347; PMCID: PMC4194089.
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Welch-Reardon KM, Ehsan SM, Wang K, Wu N, Newman AC, Romero-Lopez M, Fong AH, George SC, Edwards R, Hughes CC. Angiogenic sprouting is regulated by endothelial cell expression of Slug. J Cell Sci. 2014 May 01; 127(Pt 9):2017-28. PMID: 24554431; PMCID: PMC4004976.
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Bellet MM, Deriu E, Liu JZ, Grimaldi B, Blaschitz C, Zeller M, Edwards R, Sahar S, Dandekar S, Baldi P, George MD, Raffatellu M, Sassone-Corsi P. Circadian clock regulates the host response to Salmonella. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9897-902. PMID: 23716692; PMCID: PMC3683799.
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Jahid S, Sun J, Edwards R, Dizon D, Panarelli NC, Milsom JW, Sikandar SS, Gümüs ZH, Lipkin SM. miR-23a promotes the transition from indolent to invasive colorectal cancer. Cancer Discov. 2012 Jun; 2(6):540-53. PMID: 22628407; PMCID: PMC3651884.
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Liu JZ, Jellbauer S, Poe AJ, Ton V, Pesciaroli M, Kehl-Fie TE, Restrepo NA, Hosking MP, Edwards R, Battistoni A, Pasquali P, Lane TE, Chazin WJ, Vogl T, Roth J, Skaar EP, Raffatellu M. Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut. Cell Host Microbe. 2012 Mar 15; 11(3):227-39. PMID: 22423963; PMCID: PMC3308348.
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Yoo J, Rodriguez Perez CE, Nie W, Edwards R, Sinnett-Smith J, Rozengurt E. TNF-a induces upregulation of EGFR expression and signaling in human colonic myofibroblasts. Am J Physiol Gastrointest Liver Physiol. 2012 Apr 15; 302(8):G805-14. PMID: 22301110; PMCID: PMC3355565.
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Galitovskiy V, Qian J, Chernyavsky AI, Marchenko S, Gindi V, Edwards R, Grando SA. Cytokine-induced alterations of a7 nicotinic receptor in colonic CD4 T cells mediate dichotomous response to nicotine in murine models of Th1/Th17- versus Th2-mediated colitis. J Immunol. 2011 Sep 01; 187(5):2677-87. PMID: 21784975; PMCID: PMC4260719.
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Im SS, Yousef L, Blaschitz C, Liu JZ, Edwards R, Young SG, Raffatellu M, Osborne TF. Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a. Cell Metab. 2011 May 04; 13(5):540-9. PMID: 21531336; PMCID: PMC3090630.
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Sikandar SS, Pate KT, Anderson S, Dizon D, Edwards R, Waterman ML, Lipkin SM. NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer. Cancer Res. 2010 Feb 15; 70(4):1469-78. PMID: 20145124; PMCID: PMC4010106.
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Edwards R, Witherspoon M, Wang K, Afrasiabi K, Pham T, Birnbaumer L, Lipkin SM. Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer. Cancer Res. 2009 Aug 15; 69(16):6423-9. PMID: 19638594; PMCID: PMC2748849.
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Edwards R, Wang K, Davis JS, Birnbaumer L. Role for epithelial dysregulation in early-onset colitis-associated colon cancer in Gi2-alpha-/- mice. Inflamm Bowel Dis. 2008 Jul; 14(7):898-907. PMID: 18340649.
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Edwards R. Laser capture microdissection of mammalian tissue. J Vis Exp. 2007; (8):309. PMID: 18989416; PMCID: PMC2562492.
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Hoang B, Trinh A, Birnbaumer L, Edwards R. Decreased MAPK- and PGE2-dependent IL-11 production in Gialpha2-/- colonic myofibroblasts. Am J Physiol Gastrointest Liver Physiol. 2007 Jun; 292(6):G1511-9. PMID: 17332478.
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Edwards R, Smock AZ. Defective arachidonate release and PGE2 production in Gi alpha2-deficient intestinal and colonic subepithelial myofibroblasts. Inflamm Bowel Dis. 2006 Mar; 12(3):153-65. PMID: 16534415.
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Wu JY, Jin Y, Edwards R, Zhang Y, Finegold MJ, Wu MX. Impaired TGF-beta responses in peripheral T cells of G alpha i2-/- mice. J Immunol. 2005 May 15; 174(10):6122-8. PMID: 15879107.
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