Krzysztof Palczewski

Title(s)Professor, Ophthalmology
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-6527
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    Collapse Research 
    Collapse Research Activities and Funding
    The complex role of phosphodiesterase 6 in rod photoreceptor health and function
    NIH R01EY030873Sep 1, 2020 - Jul 31, 2024
    Role: Principal Investigator
    Opsin signaling in mammalian rod photoreceptors
    NIH R01EY030912Jun 1, 2020 - May 31, 2024
    Role: Co-Principal Investigator
    Use of systems pharmacology to prevent rod and cone photoreceptor degeneration
    NIH R24EY027283Jul 1, 2017 - Mar 31, 2022
    Role: Principal Investigator
    A two-photon ophthalmoscope for human retinal imaging and functional testing
    NIH U01EY025451May 1, 2015 - Apr 30, 2021
    Role: Principal Investigator
    Regulation of Retinal Physiology by micro-RNAs
    NIH R01EY022326Mar 1, 2013 - Feb 28, 2018
    Role: Principal Investigator
    Carotenoids in Vision
    NIH R01EY020551Nov 1, 2009 - Apr 30, 2025
    Role: Co-Principal Investigator
    Visual Sciences Training Program
    NIH T32EY007157Sep 30, 2000 - May 31, 2022
    Role: Principal Investigator
    Retinoids in Vision
    NIH R01EY009339Jan 1, 1992 - Aug 31, 2025
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The impact of nanobodies on GPCR structural biology and their potential as therapeutic agents. Mol Pharmacol. 2024 Aug 06. Salom D, Wu A, Liu CC, Palczewski K. PMID: 39107078.
      View in: PubMed   Mentions:    Fields:    
    2. A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models. Nat Commun. 2024 Jul 15; 15(1):5943. Leinonen H, Zhang J, Occelli LM, Seemab U, Choi EH, L P Marinho LF, Querubin J, Kolesnikov AV, Galinska A, Kordecka K, Hoang T, Lewandowski D, Lee TT, Einstein EE, Einstein DE, Dong Z, Kiser PD, Blackshaw S, Kefalov VJ, Tabaka M, Foik A, Petersen-Jones SM, Palczewski K. PMID: 39009597; PMCID: PMC11251169.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Conditional deletion of miR-204 and miR-211 in murine retinal pigment epithelium results in retinal degeneration. J Biol Chem. 2024 Jun; 300(6):107344. Du SW, Komirisetty R, Lewandowski D, Choi EH, Panas D, Suh S, Tabaka M, Radu RA, Palczewski K. PMID: 38705389; PMCID: PMC11140208.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    4. Dominant role for pigment epithelial CRALBP in supplying visual chromophore to photoreceptors. Cell Rep. 2024 May 28; 43(5):114143. Bassetto M, Kolesnikov AV, Lewandowski D, Kiser JZ, Halabi M, Einstein DE, Choi EH, Palczewski K, Kefalov VJ, Kiser PD. PMID: 38676924; PMCID: PMC11211020.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Restoring retinal polyunsaturated fatty acid balance and retina function by targeting ceramide in AdipoR1-deficient mice. J Biol Chem. 2024 May; 300(5):107291. Lewandowski D, Gao F, Imanishi S, Tworak A, Bassetto M, Dong Z, Pinto AFM, Tabaka M, Kiser PD, Imanishi Y, Skowronska-Krawczyk D, Palczewski K. PMID: 38636661; PMCID: PMC11107370.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    6. In Memoriam: M. Cristina Kenney, MD, PhD (1949-2023). Exp Eye Res. 2024 Jan 31; 109805. Kuppermann BD, Palczewski K. PMID: 38302293.
      View in: PubMed   Mentions:    Fields:    
    7. Retinylidene chromophore hydrolysis from mammalian visual and non-visual opsins. J Biol Chem. 2024 Mar; 300(3):105678. Hong JD, Salom D, Choi EH, Du SW, Tworak A, Smidak R, Gao F, Solano YJ, Zhang J, Kiser PD, Palczewski K. PMID: 38272218; PMCID: PMC10877631.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    8. Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo. Nat Biotechnol. 2024 Jan 08. An M, Raguram A, Du SW, Banskota S, Davis JR, Newby GA, Chen PZ, Palczewski K, Liu DR. PMID: 38191664; PMCID: PMC11228131.
      View in: PubMed   Mentions: 10     Fields:    
    9. Sex-Specific Early Retinal Dysfunction in Mutant TDP-43 Transgenic Mice. J Alzheimers Dis. 2024; 97(2):927-937. Gao J, Leinonen H, Wang EJ, Ding M, Perry G, Palczewski K, Wang X. PMID: 38143367; PMCID: PMC11174142.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    10. Distinct mouse models of Stargardt disease display differences in pharmacological targeting of ceramides and inflammatory responses. Proc Natl Acad Sci U S A. 2023 Dec 12; 120(50):e2314698120. Engfer ZJ, Lewandowski D, Dong Z, Palczewska G, Zhang J, Kordecka K, Placzkiewicz J, Panas D, Foik AT, Tabaka M, Palczewski K. PMID: 38064509; PMCID: PMC10723050.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    11. Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nat Commun. 2023 08 25; 14(1):5209. Wu A, Salom D, Hong JD, Tworak A, Watanabe K, Pardon E, Steyaert J, Kandori H, Katayama K, Kiser PD, Palczewski K. PMID: 37626045; PMCID: PMC10457330.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    12. Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia. Cell Rep. 2023 08 29; 42(8):112982. Tworak A, Kolesnikov AV, Hong JD, Choi EH, Luu JC, Palczewska G, Dong Z, Lewandowski D, Brooks MJ, Campello L, Swaroop A, Kiser PD, Kefalov VJ, Palczewski K. PMID: 37585292; PMCID: PMC10530494.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    13. Genome editing in the treatment of ocular diseases. Exp Mol Med. 2023 08; 55(8):1678-1690. Choi EH, Suh S, Sears AE, Holubowicz R, Kedhar SR, Browne AW, Palczewski K. PMID: 37524870; PMCID: PMC10474087.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    14. A short story on how chromophore is hydrolyzed from rhodopsin for recycling. Bioessays. 2023 09; 45(9):e2300068. Hong JD, Palczewski K. PMID: 37454357; PMCID: PMC10614701.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Saving eyesight, one gene at a time. Trends Mol Med. 2023 Jul; 29(7):484-486. Holubowicz R, Palczewski K. PMID: 37169661; PMCID: PMC10521062.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    16. Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition. Proc Natl Acad Sci U S A. 2023 05 09; 120(19):e2221045120. Luu JC, Saadane A, Leinonen H, Choi EH, Gao F, Lewandowski D, Halabi M, Sander CL, Wu A, Wang JM, Singh R, Gao S, Lessieur EM, Dong Z, Palczewska G, Mullins RF, Peachey NS, Kiser PD, Tabaka M, Kern TS, Palczewski K. PMID: 37126699; PMCID: PMC10175720.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    17. In vivo imaging of the human retina using a two-photon excited fluorescence ophthalmoscope. STAR Protoc. 2023 Apr 13; 4(2):102225. Boguslawski J, Tomczewski S, Dabrowski M, Komar K, Milkiewicz J, Palczewska G, Palczewski K, Wojtkowski M. PMID: 37058404; PMCID: PMC10140148.
      View in: PubMed   Mentions: 3     Fields:    
    18. Eye on genome editing. J Exp Med. 2023 05 01; 220(5). Du SW, Palczewski K. PMID: 36930175; PMCID: PMC10035435.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    19. Investigating the Role of Rhodopsin F45L Mutation in Mouse Rod Photoreceptor Signaling and Survival. eNeuro. 2023 03; 10(3). Poria D, Kolesnikov AV, Lee TJ, Salom D, Palczewski K, Kefalov VJ. PMID: 36823167; PMCID: PMC9997694.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    20. Genome editing, a superior therapy for inherited retinal diseases. Vision Res. 2023 05; 206:108192. Yan AL, Du SW, Palczewski K. PMID: 36804635; PMCID: PMC10460145.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    21. From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation. Prog Retin Eye Res. 2023 03; 93:101170. Palczewska G, Wojtkowski M, Palczewski K. PMID: 36787681; PMCID: PMC10463242.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    22. Ultrafast spectra and kinetics of human green-cone visual pigment at room temperature. Proc Natl Acad Sci U S A. 2023 01 03; 120(1):e2214276120. Dhankhar D, Salom D, Palczewski K, Rentzepis PM. PMID: 36577071; PMCID: PMC9910472.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    23. Chromophore hydrolysis and release from photoactivated rhodopsin in native membranes. Proc Natl Acad Sci U S A. 2022 Nov 08; 119(45):e2213911119. Hong JD, Salom D, Kochman MA, Kubas A, Kiser PD, Palczewski K. PMID: 36322748; PMCID: PMC9659404.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    24. Structural view of G protein-coupled receptor signaling in the retinal rod outer segment. Trends Biochem Sci. 2023 02; 48(2):172-186. Gulati S, Palczewski K. PMID: 36163145; PMCID: PMC9868064.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    25. Retinoid therapy restores eye-specific cortical responses in adult mice with retinal degeneration. Curr Biol. 2022 10 24; 32(20):4538-4546.e5. Huh CYL, Leinonen H, Nakayama T, Tomasello JR, Zhang J, Zeitoun J, Peach JP, Halabi M, Kiser JZ, Palczewski K, Kiser PD, Gandhi SP. PMID: 36152631; PMCID: PMC10083103.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    26. Precision genome editing in the eye. Proc Natl Acad Sci U S A. 2022 09 27; 119(39):e2210104119. Suh S, Choi EH, Raguram A, Liu DR, Palczewski K. PMID: 36122230; PMCID: PMC9522375.
      View in: PubMed   Mentions: 14     Fields:    
    27. Effective gene therapy of Stargardt disease with PEG-ECO/pGRK1-ABCA4-S/MAR nanoparticles. Mol Ther Nucleic Acids. 2022 Sep 13; 29:823-835. Sun D, Sun W, Gao SQ, Lehrer J, Naderi A, Wei C, Lee S, Schilb AL, Scheidt J, Hall RC, Traboulsi EI, Palczewski K, Lu ZR. PMID: 36159595; PMCID: PMC9463552.
      View in: PubMed   Mentions: 13  
    28. Deletion of Protein Phosphatase 2A Accelerates Retinal Degeneration in GRK1- and Arr1-Deficient Mice. Invest Ophthalmol Vis Sci. 2022 07 08; 63(8):18. Kolesnikov AV, Luu J, Jin H, Palczewski K, Kefalov VJ. PMID: 35861670; PMCID: PMC9315073.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    29. Visual System Hyperexcitability and Compromised V1 Receptive Field Properties in Early-Stage Retinitis Pigmentosa in Mice. eNeuro. 2022 May-Jun; 9(3). Leinonen H, Lyon DC, Palczewski K, Foik AT. PMID: 35701168; PMCID: PMC9239850.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    30. A large animal model of RDH5-associated retinopathy recapitulates important features of the human phenotype. Hum Mol Genet. 2022 04 22; 31(8):1263-1277. Occelli LM, Daruwalla A, De Silva SR, Winkler PA, Sun K, Pasmanter N, Minella A, Querubin J, Lyons LA, 99 Lives Consortium, Robson AG, Heon E, Michaelides M, Webster AR, Palczewski K, Vincent A, Mahroo OA, Kiser PD, Petersen-Jones SM. PMID: 34726233; PMCID: PMC9029234.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    31. Regenerating Skeletal Muscle Compensates for the Impaired Macrophage Functions Leading to Normal Muscle Repair in Retinol Saturase Null Mice. Cells. 2022 04 13; 11(8). Tarban N, Halász H, Gogolák P, Garabuczi É, Moise AR, Palczewski K, Sarang Z, Szondy Z. PMID: 35456012; PMCID: PMC9028072.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    32. Capturing a rhodopsin receptor signalling cascade across a native membrane. Nature. 2022 04; 604(7905):384-390. Chen S, Getter T, Salom D, Wu D, Quetschlich D, Chorev DS, Palczewski K, Robinson CV. PMID: 35388214; PMCID: PMC9007743.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    33. In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration. Nat Commun. 2022 04 05; 13(1):1830. Choi EH, Suh S, Foik AT, Leinonen H, Newby GA, Gao XD, Banskota S, Hoang T, Du SW, Dong Z, Raguram A, Kohli S, Blackshaw S, Lyon DC, Liu DR, Palczewski K. PMID: 35383196; PMCID: PMC8983734.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    34. Inhibition of ceramide accumulation in AdipoR1-/- mice increases photoreceptor survival and improves vision. JCI Insight. 2022 02 22; 7(4). Lewandowski D, Foik AT, Smidak R, Choi EH, Zhang J, Hoang T, Tworak A, Suh S, Leinonen H, Dong Z, Pinto AF, Tom E, Luu J, Lee J, Ma X, Bieberich E, Blackshaw S, Saghatelian A, Lyon DC, Skowronska-Krawczyk D, Tabaka M, Palczewski K. PMID: 35015730; PMCID: PMC8876453.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    35. In vivo imaging of the human eye using a 2-photon-excited fluorescence scanning laser ophthalmoscope. J Clin Invest. 2022 01 18; 132(2). Boguslawski J, Palczewska G, Tomczewski S, Milkiewicz J, Kasprzycki P, Stachowiak D, Komar K, Marzejon MJ, Sikorski BL, Hudzikowski A, Gluszek A, Laszczych Z, Karnowski K, Sobon G, Palczewski K, Wojtkowski M. PMID: 34847075; PMCID: PMC8759795.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    36. Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins. Cell. 2022 01 20; 185(2):250-265.e16. Banskota S, Raguram A, Suh S, Du SW, Davis JR, Choi EH, Wang X, Nielsen SC, Newby GA, Randolph PB, Osborn MJ, Musunuru K, Palczewski K, Liu DR. PMID: 35021064; PMCID: PMC8809250.
      View in: PubMed   Mentions: 152     Fields:    Translation:HumansAnimalsCells
    37. VCP/p97 inhibitor CB-5083 modulates muscle pathology in a mouse model of VCP inclusion body myopathy. J Transl Med. 2022 01 08; 20(1):21. Cheng C, Weiss L, Leinonen H, Shmara A, Yin HZ, Ton T, Do A, Lee J, Ta L, Mohanty E, Vargas J, Weiss J, Palczewski K, Kimonis V. PMID: 34998409; PMCID: PMC8742393.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    38. Determinants shaping the nanoscale architecture of the mouse rod outer segment. Elife. 2021 12 21; 10. Pöge M, Mahamid J, Imanishi SS, Plitzko JM, Palczewski K, Baumeister W. PMID: 34931611; PMCID: PMC8758146.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    39. Identification of small-molecule allosteric modulators that act as enhancers/disrupters of rhodopsin oligomerization. J Biol Chem. 2021 12; 297(6):101401. Getter T, Kemp A, Vinberg F, Palczewski K. PMID: 34774799; PMCID: PMC8665362.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    40. MicroRNA regulation of critical retinal pigment epithelial functions. Trends Neurosci. 2022 01; 45(1):78-90. Du SW, Palczewski K. PMID: 34753606; PMCID: PMC9066699.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    41. Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure. 2022 02 03; 30(2):263-277.e5. Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD. PMID: 34678158; PMCID: PMC8818024.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    42. Theoretical Study of the Photoisomerization Mechanism of All-Trans-Retinyl Acetate. J Phys Chem A. 2021 Sep 30; 125(38):8358-8372. Kochman MA, Palczewski K, Kubas A. PMID: 34546761; PMCID: PMC8488936.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    43. Regulation of Adrenergic, Serotonin, and Dopamine Receptors to Inhibit Diabetic Retinopathy: Monotherapies versus Combination Therapies. Mol Pharmacol. 2021 11; 100(5):470-479. Kern TS, Du Y, Tang J, Lee CA, Liu H, Dreffs A, Leinonen H, Antonetti DA, Palczewski K. PMID: 34393108; PMCID: PMC9175131.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    44. Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition. J Cell Biol. 2021 08 02; 220(8). Sander CL, Sears AE, Pinto AFM, Choi EH, Kahremany S, Gao F, Salom D, Jin H, Pardon E, Suh S, Dong Z, Steyaert J, Saghatelian A, Skowronska-Krawczyk D, Kiser PD, Palczewski K. PMID: 34132745; PMCID: PMC8240855.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    45. Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy. J Med Chem. 2021 06 24; 64(12):8287-8302. Blum E, Zhang J, Zaluski J, Einstein DE, Korshin EE, Kubas A, Gruzman A, Tochtrop GP, Kiser PD, Palczewski K. PMID: 34081480; PMCID: PMC8381290.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    46. THE LOSS OF INFRARED LIGHT SENSITIVITY OF PHOTORECEPTOR CELLS MEASURED WITH TWO-PHOTON EXCITATION AS AN INDICATOR OF DIABETIC RETINOPATHY: A Pilot Study. Retina. 2021 Jun 01; 41(6):1302-1308. Labuz G, Rayamajhi A, Khoramnia R, Palczewska G, Palczewski K, Holschbach A, Auffarth GU. PMID: 33323904; PMCID: PMC8137510.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    47. An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease. JCI Insight. 2021 05 10; 6(9). Choi EH, Suh S, Einstein DE, Leinonen H, Dong Z, Rao SR, Fliesler SJ, Blackshaw S, Yu M, Peachey NS, Palczewski K, Kiser PD. PMID: 33784255; PMCID: PMC8262343.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    48. New focus on regulation of the rod photoreceptor phosphodiesterase. Curr Opin Struct Biol. 2021 08; 69:99-107. Gulati S, Palczewski K. PMID: 33945959; PMCID: PMC8405451.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    49. A p97/Valosin-Containing Protein Inhibitor Drug CB-5083 Has a Potent but Reversible Off-Target Effect on Phosphodiesterase-6. J Pharmacol Exp Ther. 2021 07; 378(1):31-41. Leinonen H, Cheng C, Pitkänen M, Sander CL, Zhang J, Saeid S, Turunen T, Shmara A, Weiss L, Ta L, Ton T, Koskelainen A, Vargas JD, Kimonis V, Palczewski K. PMID: 33931547; PMCID: PMC8456514.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    50. Peptide Derivatives of Retinylamine Prevent Retinal Degeneration with Minimal Side Effects on Vision in Mice. Bioconjug Chem. 2021 03 17; 32(3):572-583. Yu G, Gao SQ, Dong Z, Sheng L, Sun D, Zhang N, Zhang J, Margeivicus S, Fu P, Golczak M, Maeda A, Palczewski K, Lu ZR. PMID: 33677964; PMCID: PMC8087159.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    51. Retinoids in the visual cycle: role of the retinal G protein-coupled receptor. J Lipid Res. 2021; 62:100040. Choi EH, Daruwalla A, Suh S, Leinonen H, Palczewski K. PMID: 32493732; PMCID: PMC7910522.
      View in: PubMed   Mentions: 24     Fields:    
    52. Function of mammalian M-cones depends on the level of CRALBP in Müller cells. J Gen Physiol. 2021 01 04; 153(1). Kolesnikov AV, Kiser PD, Palczewski K, Kefalov VJ. PMID: 33216847; PMCID: PMC7685772.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    53. Formulation and efficacy of ECO/pRHO-ABCA4-SV40 nanoparticles for nonviral gene therapy of Stargardt disease in a mouse model. J Control Release. 2021 02 10; 330:329-340. Sun D, Sun W, Gao SQ, Wei C, Naderi A, Schilb AL, Scheidt J, Lee S, Kern TS, Palczewski K, Lu ZR. PMID: 33358976; PMCID: PMC9066847.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    54. Two-photon microperimetry with picosecond pulses. Biomed Opt Express. 2021 Jan 01; 12(1):462-479. Marzejon MJ, Kornaszewski L, Boguslawski J, Ciacka P, Martynow M, Palczewska G, Mackowski S, Palczewski K, Wojtkowski M, Komar K. PMID: 33659083; PMCID: PMC7899501.
      View in: PubMed   Mentions: 7  
    55. Pathways and disease-causing alterations in visual chromophore production for vertebrate vision. J Biol Chem. 2021 Jan-Jun; 296:100072. Kiser PD, Palczewski K. PMID: 33187985; PMCID: PMC7948990.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    56. PAR4 activation involves extracellular loop 3 and transmembrane residue Thr153. Blood. 2020 11 05; 136(19):2217-2228. Han X, Hofmann L, de la Fuente M, Alexander N, Palczewski K, INVENT Consortium, Nieman MT. PMID: 32575122; PMCID: PMC7645988.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    57. Publisher Correction: Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing. Nat Biomed Eng. 2020 Nov; 4(11):1119. Suh S, Choi EH, Leinonen H, Foik AT, Newby GA, Yeh WH, Dong Z, Kiser PD, Lyon DC, Liu DR, Palczewski K. PMID: 33122854.
      View in: PubMed   Mentions: 1     Fields:    
    58. Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing. Nat Biomed Eng. 2021 02; 5(2):169-178. Suh S, Choi EH, Leinonen H, Foik AT, Newby GA, Yeh WH, Dong Z, Kiser PD, Lyon DC, Liu DR, Palczewski K. PMID: 33077938; PMCID: PMC7885272.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    59. Homeostatic plasticity in the retina is associated with maintenance of night vision during retinal degenerative disease. Elife. 2020 09 22; 9. Leinonen H, Pham NC, Boyd T, Santoso J, Palczewski K, Vinberg F. PMID: 32960171; PMCID: PMC7529457.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    60. Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model. Hum Mol Genet. 2020 08 29; 29(15):2611-2624. Luu J, Kallestad L, Hoang T, Lewandowski D, Dong Z, Blackshaw S, Palczewski K. PMID: 32691052; PMCID: PMC7471509.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    61. Single particle cryo-EM of the complex between interphotoreceptor retinoid-binding protein and a monoclonal antibody. FASEB J. 2020 10; 34(10):13918-13934. Sears AE, Albiez S, Gulati S, Wang B, Kiser P, Kovacik L, Engel A, Stahlberg H, Palczewski K. PMID: 32860273; PMCID: PMC7589273.
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