Krzysztof Palczewski

Title(s)Professor, Ophthalmology
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-6527
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    The complex role of phosphodiesterase 6 in rod photoreceptor health and function
    NIH R01EY030873Sep 1, 2020 - Jul 31, 2024
    Role: Principal Investigator
    Opsin signaling in mammalian rod photoreceptors
    NIH R01EY030912Jun 1, 2020 - May 31, 2024
    Role: Co-Principal Investigator
    Use of systems pharmacology to prevent rod and cone photoreceptor degeneration
    NIH R24EY027283Jul 1, 2017 - Mar 31, 2022
    Role: Principal Investigator
    A two-photon ophthalmoscope for human retinal imaging and functional testing
    NIH U01EY025451May 1, 2015 - Apr 30, 2021
    Role: Principal Investigator
    Regulation of Retinal Physiology by micro-RNAs
    NIH R01EY022326Mar 1, 2013 - Feb 28, 2018
    Role: Principal Investigator
    Carotenoids in Vision
    NIH R01EY020551Nov 1, 2009 - Apr 30, 2025
    Role: Co-Principal Investigator
    Visual Sciences Training Program
    NIH T32EY007157Sep 30, 2000 - May 31, 2022
    Role: Principal Investigator
    Retinoids in Vision
    NIH R01EY009339Jan 1, 1992 - Aug 31, 2025
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. In Memoriam: M. Cristina Kenney, MD, PhD (1949-2023). Exp Eye Res. 2024 Jan 31; 109805. Kuppermann BD, Palczewski K. PMID: 38302293.
      View in: PubMed   Mentions:    Fields:    
    2. Retinylidene chromophore hydrolysis from mammalian visual and non-visual opsins. J Biol Chem. 2024 Mar; 300(3):105678. Hong JD, Salom D, Choi EH, Du SW, Tworak A, Smidak R, Gao F, Solano YJ, Zhang J, Kiser PD, Palczewski K. PMID: 38272218; PMCID: PMC10877631.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo. Nat Biotechnol. 2024 Jan 08. An M, Raguram A, Du SW, Banskota S, Davis JR, Newby GA, Chen PZ, Palczewski K, Liu DR. PMID: 38191664.
      View in: PubMed   Mentions:    Fields:    
    4. Sex-Specific Early Retinal Dysfunction in Mutant TDP-43 Transgenic Mice. J Alzheimers Dis. 2024; 97(2):927-937. Gao J, Leinonen H, Wang EJ, Ding M, Perry G, Palczewski K, Wang X. PMID: 38143367.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    5. Distinct mouse models of Stargardt disease display differences in pharmacological targeting of ceramides and inflammatory responses. Proc Natl Acad Sci U S A. 2023 Dec 12; 120(50):e2314698120. Engfer ZJ, Lewandowski D, Dong Z, Palczewska G, Zhang J, Kordecka K, Placzkiewicz J, Panas D, Foik AT, Tabaka M, Palczewski K. PMID: 38064509; PMCID: PMC10723050.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    6. Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nat Commun. 2023 08 25; 14(1):5209. Wu A, Salom D, Hong JD, Tworak A, Watanabe K, Pardon E, Steyaert J, Kandori H, Katayama K, Kiser PD, Palczewski K. PMID: 37626045; PMCID: PMC10457330.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    7. Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia. Cell Rep. 2023 08 29; 42(8):112982. Tworak A, Kolesnikov AV, Hong JD, Choi EH, Luu JC, Palczewska G, Dong Z, Lewandowski D, Brooks MJ, Campello L, Swaroop A, Kiser PD, Kefalov VJ, Palczewski K. PMID: 37585292; PMCID: PMC10530494.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    8. Genome editing in the treatment of ocular diseases. Exp Mol Med. 2023 08; 55(8):1678-1690. Choi EH, Suh S, Sears AE, Holubowicz R, Kedhar SR, Browne AW, Palczewski K. PMID: 37524870; PMCID: PMC10474087.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. A short story on how chromophore is hydrolyzed from rhodopsin for recycling. Bioessays. 2023 09; 45(9):e2300068. Hong JD, Palczewski K. PMID: 37454357; PMCID: PMC10614701.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Saving eyesight, one gene at a time. Trends Mol Med. 2023 Jul; 29(7):484-486. Holubowicz R, Palczewski K. PMID: 37169661; PMCID: PMC10521062.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    11. Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition. Proc Natl Acad Sci U S A. 2023 05 09; 120(19):e2221045120. Luu JC, Saadane A, Leinonen H, Choi EH, Gao F, Lewandowski D, Halabi M, Sander CL, Wu A, Wang JM, Singh R, Gao S, Lessieur EM, Dong Z, Palczewska G, Mullins RF, Peachey NS, Kiser PD, Tabaka M, Kern TS, Palczewski K. PMID: 37126699; PMCID: PMC10175720.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. In vivo imaging of the human retina using a two-photon excited fluorescence ophthalmoscope. STAR Protoc. 2023 Apr 13; 4(2):102225. Boguslawski J, Tomczewski S, Dabrowski M, Komar K, Milkiewicz J, Palczewska G, Palczewski K, Wojtkowski M. PMID: 37058404; PMCID: PMC10140148.
      View in: PubMed   Mentions: 2     Fields:    
    13. Eye on genome editing. J Exp Med. 2023 05 01; 220(5). Du SW, Palczewski K. PMID: 36930175; PMCID: PMC10035435.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    14. Investigating the Role of Rhodopsin F45L Mutation in Mouse Rod Photoreceptor Signaling and Survival. eNeuro. 2023 03; 10(3). Poria D, Kolesnikov AV, Lee TJ, Salom D, Palczewski K, Kefalov VJ. PMID: 36823167; PMCID: PMC9997694.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    15. Genome editing, a superior therapy for inherited retinal diseases. Vision Res. 2023 05; 206:108192. Yan AL, Du SW, Palczewski K. PMID: 36804635; PMCID: PMC10460145.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    16. From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation. Prog Retin Eye Res. 2023 03; 93:101170. Palczewska G, Wojtkowski M, Palczewski K. PMID: 36787681; PMCID: PMC10463242.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    17. Ultrafast spectra and kinetics of human green-cone visual pigment at room temperature. Proc Natl Acad Sci U S A. 2023 01 03; 120(1):e2214276120. Dhankhar D, Salom D, Palczewski K, Rentzepis PM. PMID: 36577071; PMCID: PMC9910472.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    18. Chromophore hydrolysis and release from photoactivated rhodopsin in native membranes. Proc Natl Acad Sci U S A. 2022 Nov 08; 119(45):e2213911119. Hong JD, Salom D, Kochman MA, Kubas A, Kiser PD, Palczewski K. PMID: 36322748; PMCID: PMC9659404.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    19. Structural view of G protein-coupled receptor signaling in the retinal rod outer segment. Trends Biochem Sci. 2023 02; 48(2):172-186. Gulati S, Palczewski K. PMID: 36163145; PMCID: PMC9868064.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    20. Retinoid therapy restores eye-specific cortical responses in adult mice with retinal degeneration. Curr Biol. 2022 10 24; 32(20):4538-4546.e5. Huh CYL, Leinonen H, Nakayama T, Tomasello JR, Zhang J, Zeitoun J, Peach JP, Halabi M, Kiser JZ, Palczewski K, Kiser PD, Gandhi SP. PMID: 36152631; PMCID: PMC10083103.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    21. Precision genome editing in the eye. Proc Natl Acad Sci U S A. 2022 09 27; 119(39):e2210104119. Suh S, Choi EH, Raguram A, Liu DR, Palczewski K. PMID: 36122230; PMCID: PMC9522375.
      View in: PubMed   Mentions: 12     Fields:    
    22. Effective gene therapy of Stargardt disease with PEG-ECO/pGRK1-ABCA4-S/MAR nanoparticles. Mol Ther Nucleic Acids. 2022 Sep 13; 29:823-835. Sun D, Sun W, Gao SQ, Lehrer J, Naderi A, Wei C, Lee S, Schilb AL, Scheidt J, Hall RC, Traboulsi EI, Palczewski K, Lu ZR. PMID: 36159595; PMCID: PMC9463552.
      View in: PubMed   Mentions: 9  
    23. Deletion of Protein Phosphatase 2A Accelerates Retinal Degeneration in GRK1- and Arr1-Deficient Mice. Invest Ophthalmol Vis Sci. 2022 07 08; 63(8):18. Kolesnikov AV, Luu J, Jin H, Palczewski K, Kefalov VJ. PMID: 35861670; PMCID: PMC9315073.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    24. Visual System Hyperexcitability and Compromised V1 Receptive Field Properties in Early-Stage Retinitis Pigmentosa in Mice. eNeuro. 2022 May-Jun; 9(3). Leinonen H, Lyon DC, Palczewski K, Foik AT. PMID: 35701168; PMCID: PMC9239850.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    25. A large animal model of RDH5-associated retinopathy recapitulates important features of the human phenotype. Hum Mol Genet. 2022 04 22; 31(8):1263-1277. Occelli LM, Daruwalla A, De Silva SR, Winkler PA, Sun K, Pasmanter N, Minella A, Querubin J, Lyons LA, 99 Lives Consortium, Robson AG, Heon E, Michaelides M, Webster AR, Palczewski K, Vincent A, Mahroo OA, Kiser PD, Petersen-Jones SM. PMID: 34726233; PMCID: PMC9029234.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    26. Regenerating Skeletal Muscle Compensates for the Impaired Macrophage Functions Leading to Normal Muscle Repair in Retinol Saturase Null Mice. Cells. 2022 04 13; 11(8). Tarban N, Halász H, Gogolák P, Garabuczi É, Moise AR, Palczewski K, Sarang Z, Szondy Z. PMID: 35456012; PMCID: PMC9028072.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    27. Capturing a rhodopsin receptor signalling cascade across a native membrane. Nature. 2022 04; 604(7905):384-390. Chen S, Getter T, Salom D, Wu D, Quetschlich D, Chorev DS, Palczewski K, Robinson CV. PMID: 35388214; PMCID: PMC9007743.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    28. In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration. Nat Commun. 2022 04 05; 13(1):1830. Choi EH, Suh S, Foik AT, Leinonen H, Newby GA, Gao XD, Banskota S, Hoang T, Du SW, Dong Z, Raguram A, Kohli S, Blackshaw S, Lyon DC, Liu DR, Palczewski K. PMID: 35383196; PMCID: PMC8983734.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    29. Inhibition of ceramide accumulation in AdipoR1-/- mice increases photoreceptor survival and improves vision. JCI Insight. 2022 02 22; 7(4). Lewandowski D, Foik AT, Smidak R, Choi EH, Zhang J, Hoang T, Tworak A, Suh S, Leinonen H, Dong Z, Pinto AF, Tom E, Luu J, Lee J, Ma X, Bieberich E, Blackshaw S, Saghatelian A, Lyon DC, Skowronska-Krawczyk D, Tabaka M, Palczewski K. PMID: 35015730; PMCID: PMC8876453.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    30. In vivo imaging of the human eye using a 2-photon-excited fluorescence scanning laser ophthalmoscope. J Clin Invest. 2022 01 18; 132(2). Boguslawski J, Palczewska G, Tomczewski S, Milkiewicz J, Kasprzycki P, Stachowiak D, Komar K, Marzejon MJ, Sikorski BL, Hudzikowski A, Gluszek A, Laszczych Z, Karnowski K, Sobon G, Palczewski K, Wojtkowski M. PMID: 34847075; PMCID: PMC8759795.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    31. Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins. Cell. 2022 01 20; 185(2):250-265.e16. Banskota S, Raguram A, Suh S, Du SW, Davis JR, Choi EH, Wang X, Nielsen SC, Newby GA, Randolph PB, Osborn MJ, Musunuru K, Palczewski K, Liu DR. PMID: 35021064; PMCID: PMC8809250.
      View in: PubMed   Mentions: 130     Fields:    
    32. VCP/p97 inhibitor CB-5083 modulates muscle pathology in a mouse model of VCP inclusion body myopathy. J Transl Med. 2022 01 08; 20(1):21. Cheng C, Weiss L, Leinonen H, Shmara A, Yin HZ, Ton T, Do A, Lee J, Ta L, Mohanty E, Vargas J, Weiss J, Palczewski K, Kimonis V. PMID: 34998409; PMCID: PMC8742393.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    33. Determinants shaping the nanoscale architecture of the mouse rod outer segment. Elife. 2021 12 21; 10. Pöge M, Mahamid J, Imanishi SS, Plitzko JM, Palczewski K, Baumeister W. PMID: 34931611; PMCID: PMC8758146.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    34. Identification of small-molecule allosteric modulators that act as enhancers/disrupters of rhodopsin oligomerization. J Biol Chem. 2021 12; 297(6):101401. Getter T, Kemp A, Vinberg F, Palczewski K. PMID: 34774799; PMCID: PMC8665362.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    35. MicroRNA regulation of critical retinal pigment epithelial functions. Trends Neurosci. 2022 01; 45(1):78-90. Du SW, Palczewski K. PMID: 34753606; PMCID: PMC9066699.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    36. Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure. 2022 02 03; 30(2):263-277.e5. Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD. PMID: 34678158; PMCID: PMC8818024.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    37. Theoretical Study of the Photoisomerization Mechanism of All-Trans-Retinyl Acetate. J Phys Chem A. 2021 Sep 30; 125(38):8358-8372. Kochman MA, Palczewski K, Kubas A. PMID: 34546761; PMCID: PMC8488936.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    38. Regulation of Adrenergic, Serotonin, and Dopamine Receptors to Inhibit Diabetic Retinopathy: Monotherapies versus Combination Therapies. Mol Pharmacol. 2021 11; 100(5):470-479. Kern TS, Du Y, Tang J, Lee CA, Liu H, Dreffs A, Leinonen H, Antonetti DA, Palczewski K. PMID: 34393108; PMCID: PMC9175131.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    39. Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition. J Cell Biol. 2021 08 02; 220(8). Sander CL, Sears AE, Pinto AFM, Choi EH, Kahremany S, Gao F, Salom D, Jin H, Pardon E, Suh S, Dong Z, Steyaert J, Saghatelian A, Skowronska-Krawczyk D, Kiser PD, Palczewski K. PMID: 34132745; PMCID: PMC8240855.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    40. Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy. J Med Chem. 2021 06 24; 64(12):8287-8302. Blum E, Zhang J, Zaluski J, Einstein DE, Korshin EE, Kubas A, Gruzman A, Tochtrop GP, Kiser PD, Palczewski K. PMID: 34081480; PMCID: PMC8381290.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    41. THE LOSS OF INFRARED LIGHT SENSITIVITY OF PHOTORECEPTOR CELLS MEASURED WITH TWO-PHOTON EXCITATION AS AN INDICATOR OF DIABETIC RETINOPATHY: A Pilot Study. Retina. 2021 Jun 01; 41(6):1302-1308. Labuz G, Rayamajhi A, Khoramnia R, Palczewska G, Palczewski K, Holschbach A, Auffarth GU. PMID: 33323904; PMCID: PMC8137510.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    42. An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease. JCI Insight. 2021 05 10; 6(9). Choi EH, Suh S, Einstein DE, Leinonen H, Dong Z, Rao SR, Fliesler SJ, Blackshaw S, Yu M, Peachey NS, Palczewski K, Kiser PD. PMID: 33784255; PMCID: PMC8262343.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    43. New focus on regulation of the rod photoreceptor phosphodiesterase. Curr Opin Struct Biol. 2021 08; 69:99-107. Gulati S, Palczewski K. PMID: 33945959; PMCID: PMC8405451.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    44. A p97/Valosin-Containing Protein Inhibitor Drug CB-5083 Has a Potent but Reversible Off-Target Effect on Phosphodiesterase-6. J Pharmacol Exp Ther. 2021 07; 378(1):31-41. Leinonen H, Cheng C, Pitkänen M, Sander CL, Zhang J, Saeid S, Turunen T, Shmara A, Weiss L, Ta L, Ton T, Koskelainen A, Vargas JD, Kimonis V, Palczewski K. PMID: 33931547; PMCID: PMC8456514.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    45. Peptide Derivatives of Retinylamine Prevent Retinal Degeneration with Minimal Side Effects on Vision in Mice. Bioconjug Chem. 2021 03 17; 32(3):572-583. Yu G, Gao SQ, Dong Z, Sheng L, Sun D, Zhang N, Zhang J, Margeivicus S, Fu P, Golczak M, Maeda A, Palczewski K, Lu ZR. PMID: 33677964; PMCID: PMC8087159.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    46. Retinoids in the visual cycle: role of the retinal G protein-coupled receptor. J Lipid Res. 2021; 62:100040. Choi EH, Daruwalla A, Suh S, Leinonen H, Palczewski K. PMID: 32493732; PMCID: PMC7910522.
      View in: PubMed   Mentions: 18     Fields:    
    47. Function of mammalian M-cones depends on the level of CRALBP in Müller cells. J Gen Physiol. 2021 01 04; 153(1). Kolesnikov AV, Kiser PD, Palczewski K, Kefalov VJ. PMID: 33216847; PMCID: PMC7685772.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    48. Formulation and efficacy of ECO/pRHO-ABCA4-SV40 nanoparticles for nonviral gene therapy of Stargardt disease in a mouse model. J Control Release. 2021 02 10; 330:329-340. Sun D, Sun W, Gao SQ, Wei C, Naderi A, Schilb AL, Scheidt J, Lee S, Kern TS, Palczewski K, Lu ZR. PMID: 33358976; PMCID: PMC9066847.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    49. Two-photon microperimetry with picosecond pulses. Biomed Opt Express. 2021 Jan 01; 12(1):462-479. Marzejon MJ, Kornaszewski L, Boguslawski J, Ciacka P, Martynow M, Palczewska G, Mackowski S, Palczewski K, Wojtkowski M, Komar K. PMID: 33659083; PMCID: PMC7899501.
      View in: PubMed   Mentions: 6  
    50. Pathways and disease-causing alterations in visual chromophore production for vertebrate vision. J Biol Chem. 2021 Jan-Jun; 296:100072. Kiser PD, Palczewski K. PMID: 33187985; PMCID: PMC7948990.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    51. PAR4 activation involves extracellular loop 3 and transmembrane residue Thr153. Blood. 2020 11 05; 136(19):2217-2228. Han X, Hofmann L, de la Fuente M, Alexander N, Palczewski K, INVENT Consortium, Nieman MT. PMID: 32575122; PMCID: PMC7645988.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    52. Publisher Correction: Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing. Nat Biomed Eng. 2020 Nov; 4(11):1119. Suh S, Choi EH, Leinonen H, Foik AT, Newby GA, Yeh WH, Dong Z, Kiser PD, Lyon DC, Liu DR, Palczewski K. PMID: 33122854.
      View in: PubMed   Mentions: 2     Fields:    
    53. Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing. Nat Biomed Eng. 2021 02; 5(2):169-178. Suh S, Choi EH, Leinonen H, Foik AT, Newby GA, Yeh WH, Dong Z, Kiser PD, Lyon DC, Liu DR, Palczewski K. PMID: 33077938; PMCID: PMC7885272.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    54. Homeostatic plasticity in the retina is associated with maintenance of night vision during retinal degenerative disease. Elife. 2020 09 22; 9. Leinonen H, Pham NC, Boyd T, Santoso J, Palczewski K, Vinberg F. PMID: 32960171; PMCID: PMC7529457.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    55. Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model. Hum Mol Genet. 2020 08 29; 29(15):2611-2624. Luu J, Kallestad L, Hoang T, Lewandowski D, Dong Z, Blackshaw S, Palczewski K. PMID: 32691052; PMCID: PMC7471509.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    56. Single particle cryo-EM of the complex between interphotoreceptor retinoid-binding protein and a monoclonal antibody. FASEB J. 2020 10; 34(10):13918-13934. Sears AE, Albiez S, Gulati S, Wang B, Kiser P, Kovacik L, Engel A, Stahlberg H, Palczewski K. PMID: 32860273; PMCID: PMC7589273.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    57. Noninvasive two-photon optical biopsy of retinal fluorophores. Proc Natl Acad Sci U S A. 2020 09 08; 117(36):22532-22543. Palczewska G, Boguslawski J, Stremplewski P, Kornaszewski L, Zhang J, Dong Z, Liang XX, Gratton E, Vogel A, Wojtkowski M, Palczewski K. PMID: 32848058; PMCID: PMC7486747.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    58. Shedding new light on the generation of the visual chromophore. Proc Natl Acad Sci U S A. 2020 08 18; 117(33):19629-19638. Palczewski K, Kiser PD. PMID: 32759209; PMCID: PMC7443880.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    59. Development of chiral fluorinated alkyl derivatives of emixustat as drug candidates for the treatment of retinal degenerative diseases. Bioorg Med Chem Lett. 2020 09 15; 30(18):127421. Blum E, Zhang J, Korshin E, Palczewski K, Gruzman A. PMID: 32717613; PMCID: PMC7494577.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    60. Clinical Application of Infrared-Light Microperimetry in the Assessment of Scotopic-Eye Sensitivity. Transl Vis Sci Technol. 2020 07; 9(8):7. Labuz G, Rayamajhi A, Usinger J, Komar K, Merz P, Khoramnia R, Palczewska G, Palczewski K, Auffarth GU. PMID: 32855854; PMCID: PMC7422764.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    61. PCARE and WASF3 regulate ciliary F-actin assembly that is required for the initiation of photoreceptor outer segment disk formation. Proc Natl Acad Sci U S A. 2020 05 05; 117(18):9922-9931. Corral-Serrano JC, Lamers IJC, van Reeuwijk J, Duijkers L, Hoogendoorn ADM, Yildirim A, Argyrou N, Ruigrok RAA, Letteboer SJF, Butcher R, van Essen MD, Sakami S, van Beersum SEC, Palczewski K, Cheetham ME, Liu Q, Boldt K, Wolfrum U, Ueffing M, Garanto A, Roepman R, Collin RWJ. PMID: 32312818; PMCID: PMC7211956.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    62. Stable Retinoid Analogue Targeted Dual pH-Sensitive Smart Lipid ECO/pDNA Nanoparticles for Specific Gene Delivery in the Retinal Pigment Epithelium. ACS Appl Bio Mater. 2020 May 18; 3(5):3078-3086. Sun D, Schur RM, Sears AE, Gao SQ, Sun W, Naderi A, Kern T, Palczewski K, Lu ZR. PMID: 34327311; PMCID: PMC8317636.
      View in: PubMed   Mentions: 10     Fields:    
    63. Melanopsin Carboxy-terminus phosphorylation plasticity and bulk negative charge, not strict site specificity, achieves phototransduction deactivation. PLoS One. 2020; 15(4):e0228121. Valdez-Lopez JC, Gulati S, Ortiz EA, Palczewski K, Robinson PR. PMID: 32236094; PMCID: PMC7112210.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    64. Retinol Saturase Knock-Out Mice are Characterized by Impaired Clearance of Apoptotic Cells and Develop Mild Autoimmunity. Biomolecules. 2019 11 13; 9(11). Sarang Z, Sághy T, Budai Z, Ujlaky-Nagy L, Bedekovics J, Beke L, Méhes G, Nagy G, Rühl R, Moise AR, Palczewski K, Szondy Z. PMID: 31766264; PMCID: PMC6920856.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    65. Photic generation of 11-cis-retinal in bovine retinal pigment epithelium. J Biol Chem. 2019 12 13; 294(50):19137-19154. Zhang J, Choi EH, Tworak A, Salom D, Leinonen H, Sander CL, Hoang TV, Handa JT, Blackshaw S, Palczewska G, Kiser PD, Palczewski K. PMID: 31694912; PMCID: PMC6916499.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    66. Tissue- and Species-Specific Patterns of RNA metabolism in Post-Mortem Mammalian Retina and Retinal Pigment Epithelium. Sci Rep. 2019 10 15; 9(1):14821. Kallestad L, Blackshaw S, Khalil AM, Palczewski K. PMID: 31616038; PMCID: PMC6794289.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    67. Non-viral Gene Therapy for Stargardt Disease with ECO/pRHO-ABCA4 Self-Assembled Nanoparticles. Mol Ther. 2020 01 08; 28(1):293-303. Sun D, Schur RM, Sears AE, Gao SQ, Vaidya A, Sun W, Maeda A, Kern T, Palczewski K, Lu ZR. PMID: 31611143; PMCID: PMC6952167.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    68. Z-isomerization of retinoids through combination of monochromatic photoisomerization and metal catalysis. Org Biomol Chem. 2019 09 21; 17(35):8125-8139. Kahremany S, Sander CL, Tochtrop GP, Kubas A, Palczewski K. PMID: 31455964; PMCID: PMC6739180.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    69. Two-photon microperimetry: sensitivity of human photoreceptors to infrared light. Biomed Opt Express. 2019 Sep 01; 10(9):4551-4567. Ruminski D, Palczewska G, Nowakowski M, Zielinska A, Kefalov VJ, Komar K, Palczewski K, Wojtkowski M. PMID: 31565509; PMCID: PMC6757456.
      View in: PubMed   Mentions: 15  
    70. Cryo-EM structure of the native rhodopsin dimer in nanodiscs. J Biol Chem. 2019 09 27; 294(39):14215-14230. Zhao DY, Pöge M, Morizumi T, Gulati S, Van Eps N, Zhang J, Miszta P, Filipek S, Mahamid J, Plitzko JM, Baumeister W, Ernst OP, Palczewski K. PMID: 31399513; PMCID: PMC6768649.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    71. Sensitivity of Mammalian Cone Photoreceptors to Infrared Light. Neuroscience. 2019 09 15; 416:100-108. Vinberg F, Palczewska G, Zhang J, Komar K, Wojtkowski M, Kefalov VJ, Palczewski K. PMID: 31400484; PMCID: PMC6815255.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    72. Catalytic synthesis of 9-cis-retinoids: mechanistic insights. Dalton Trans. 2019 Jul 16; 48(28):10581-10595. Kahremany S, Kubas A, Tochtrop GP, Palczewski K. PMID: 31218312; PMCID: PMC7004310.
      View in: PubMed   Mentions: 5     Fields:    
    73. Stereospecific modulation of dimeric rhodopsin. FASEB J. 2019 08; 33(8):9526-9539. Getter T, Gulati S, Zimmerman R, Chen Y, Vinberg F, Palczewski K. PMID: 31121099; PMCID: PMC6662988.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    74. Retinal Gene Distribution and Functionality Implicated in Inherited Retinal Degenerations Can Reveal Disease-Relevant Pathways for Pharmacologic Intervention. Pharmaceuticals (Basel). 2019 May 17; 12(2). Mustafi D, Arbabi A, Ameri H, Palczewski K. PMID: 31108889; PMCID: PMC6631933.
      View in: PubMed   Mentions: 4  
    75. The selective estrogen receptor modulator raloxifene mitigates the effect of all-trans-retinal toxicity in photoreceptor degeneration. J Biol Chem. 2019 06 14; 294(24):9461-9475. Getter T, Suh S, Hoang T, Handa JT, Dong Z, Ma X, Chen Y, Blackshaw S, Palczewski K. PMID: 31073029; PMCID: PMC6579480.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    76. Human red and green cone opsins are O-glycosylated at an N-terminal Ser/Thr-rich domain conserved in vertebrates. J Biol Chem. 2019 05 17; 294(20):8123-8133. Salom D, Jin H, Gerken TA, Yu C, Huang L, Palczewski K. PMID: 30948514; PMCID: PMC6527158.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    77. A Mixture of U.S. Food and Drug Administration-Approved Monoaminergic Drugs Protects the Retina From Light Damage in Diverse Models of Night Blindness. Invest Ophthalmol Vis Sci. 2019 04 01; 60(5):1442-1453. Leinonen H, Choi EH, Gardella A, Kefalov VJ, Palczewski K. PMID: 30947334; PMCID: PMC6736410.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    78. Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2019 04 01; 60(5):1538-1546. Liu H, Tang J, Du Y, Saadane A, Samuels I, Veenstra A, Kiser JZ, Palczewski K, Kern TS. PMID: 30994864; PMCID: PMC6736377.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    79. Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases. Sci Adv. 2019 02; 5(2):eaav4322. Gulati S, Palczewski K, Engel A, Stahlberg H, Kovacik L. PMID: 30820458; PMCID: PMC6392808.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    80. Specificity of the chromophore-binding site in human cone opsins. J Biol Chem. 2019 04 12; 294(15):6082-6093. Katayama K, Gulati S, Ortega JT, Alexander NS, Sun W, Shenouda MM, Palczewski K, Jastrzebska B. PMID: 30770468; PMCID: PMC6463688.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    81. Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones. FASEB J. 2019 04; 33(4):5782-5792. Kiser PD, Kolesnikov AV, Kiser JZ, Dong Z, Chaurasia B, Wang L, Summers SA, Hoang T, Blackshaw S, Peachey NS, Kefalov VJ, Palczewski K. PMID: 30645148; PMCID: PMC6436658.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    82. Immuno-TEM/STEM in Retinal Research. Methods Mol Biol. 2019; 1834:311-332. Sakami S, Palczewski K. PMID: 30324452; PMCID: PMC6991117.
      View in: PubMed   Mentions:    Fields:    
    83. Noninvasive Two-Photon Microscopy Imaging of Mouse Retina and Retinal Pigment Epithelium. Methods Mol Biol. 2019; 1834:333-343. Palczewska G, Kern TS, Palczewski K. PMID: 30324453; PMCID: PMC6991118.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    84. Müller glia phagocytose dead photoreceptor cells in a mouse model of retinal degenerative disease. FASEB J. 2019 03; 33(3):3680-3692. Sakami S, Imanishi Y, Palczewski K. PMID: 30462532; PMCID: PMC6404573.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    85. Apo-Opsin Exists in Equilibrium Between a Predominant Inactive and a Rare Highly Active State. J Neurosci. 2019 01 09; 39(2):212-223. Sato S, Jastrzebska B, Engel A, Palczewski K, Kefalov VJ. PMID: 30459230; PMCID: PMC6325258.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    86. Structural biology of 11-cis-retinaldehyde production in the classical visual cycle. Biochem J. 2018 10 22; 475(20):3171-3188. Daruwalla A, Choi EH, Palczewski K, Kiser PD. PMID: 30352831; PMCID: PMC6440480.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    87. Two-photon imaging of the mammalian retina with ultrafast pulsing laser. JCI Insight. 2018 09 06; 3(17). Palczewska G, Stremplewski P, Suh S, Alexander N, Salom D, Dong Z, Ruminski D, Choi EH, Sears AE, Kern TS, Wojtkowski M, Palczewski K. PMID: 30185665; PMCID: PMC6171813.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    88. Protective Effect of a Locked Retinal Chromophore Analog against Light-Induced Retinal Degeneration. Mol Pharmacol. 2018 10; 94(4):1132-1144. Gao S, Parmar T, Palczewska G, Dong Z, Golczak M, Palczewski K, Jastrzebska B. PMID: 30018116; PMCID: PMC6108575.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    89. Exploring a new ligand binding site of G protein-coupled receptors. Chem Sci. 2018 Aug 21; 9(31):6480-6489. Chan HCS, Wang J, Palczewski K, Filipek S, Vogel H, Liu ZJ, Yuan S. PMID: 30310578; PMCID: PMC6115637.
      View in: PubMed   Mentions: 19  
    90. Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65. Hum Mol Genet. 2018 07 01; 27(13):2225-2243. Choi EH, Suh S, Sander CL, Hernandez CJO, Bulman ER, Khadka N, Dong Z, Shi W, Palczewski K, Kiser PD. PMID: 29659842; PMCID: PMC6005012.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    91. Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor. Nat Commun. 2018 05 18; 9(1):1996. Gulati S, Jin H, Masuho I, Orban T, Cai Y, Pardon E, Martemyanov KA, Kiser PD, Stewart PL, Ford CP, Steyaert J, Palczewski K. PMID: 29777099; PMCID: PMC5959942.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    92. A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration. Nat Commun. 2018 05 17; 9(1):1976. Chen Y, Chen Y, Jastrzebska B, Golczak M, Gulati S, Tang H, Seibel W, Li X, Jin H, Han Y, Gao S, Zhang J, Liu X, Heidari-Torkabadi H, Stewart PL, Harte WE, Tochtrop GP, Palczewski K. PMID: 29773803; PMCID: PMC5958115.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    93. A Small Chaperone Improves Folding and Routing of Rhodopsin Mutants Linked to Inherited Blindness. iScience. 2018 Jun 29; 4:1-19. Behnen P, Felline A, Comitato A, Di Salvo MT, Raimondi F, Gulati S, Kahremany S, Palczewski K, Marigo V, Fanelli F. PMID: 30240733; PMCID: PMC6147235.
      View in: PubMed   Mentions: 26  
    94. Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function. J Gen Physiol. 2018 04 02; 150(4):571-590. Kiser PD, Zhang J, Sharma A, Angueyra JM, Kolesnikov AV, Badiee M, Tochtrop GP, Kinoshita J, Peachey NS, Li W, Kefalov VJ, Palczewski K. PMID: 29500274; PMCID: PMC5881442.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    95. Human aging and disease: Lessons from age-related macular degeneration. Proc Natl Acad Sci U S A. 2018 03 20; 115(12):2866-2872. Luu J, Palczewski K. PMID: 29483257; PMCID: PMC5866596.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    96. Retinal-chitosan Conjugates Effectively Deliver Active Chromophores to Retinal Photoreceptor Cells in Blind Mice and Dogs. Mol Pharmacol. 2018 05; 93(5):438-452. Gao S, Kahremany S, Zhang J, Jastrzebska B, Querubin J, Petersen-Jones SM, Palczewski K. PMID: 29453250; PMCID: PMC5878677.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    97. Increasing the Stability of Recombinant Human Green Cone Pigment. Biochemistry. 2018 02 13; 57(6):1022-1030. Owen TS, Salom D, Sun W, Palczewski K. PMID: 29320632; PMCID: PMC5853123.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    98. New GABA modulators protect photoreceptor cells from light-induced degeneration in mouse models. FASEB J. 2018 06; 32(6):3289-3300. Schur RM, Gao S, Yu G, Chen Y, Maeda A, Palczewski K, Lu ZR. PMID: 29401616; PMCID: PMC5956245.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    99. An Expedient Synthesis of CMF-019: (S)-5-Methyl-3-{1-(pentan-3-yl)-2- (thiophen-2-ylmethyl)-1H-benzo[d]imidazole-5-carboxamido}hexanoic Acid, a Potent Apelin Receptor (APJ) Agonist. Med Chem. 2018; 14(7):688-694. Trifonov L, Afri M, Palczewski K, Korshin EE, Gruzman A. PMID: 29651942; PMCID: PMC6993063.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    100. A Combination of G Protein-Coupled Receptor Modulators Protects Photoreceptors from Degeneration. J Pharmacol Exp Ther. 2018 02; 364(2):207-220. Orban T, Leinonen H, Getter T, Dong Z, Sun W, Gao S, Veenstra A, Heidari-Torkabadi H, Kern TS, Kiser PD, Palczewski K. PMID: 29162627; PMCID: PMC5771314.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    101. Context-dependent compensation among phosphatidylserine-recognition receptors. Sci Rep. 2017 11 07; 7(1):14623. Penberthy KK, Rival C, Shankman LS, Raymond MH, Zhang J, Perry JSA, Lee CS, Han CZ, Onengut-Gumuscu S, Palczewski K, Lysiak JJ, Ravichandran KS. PMID: 29116131; PMCID: PMC5676788.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    102. Multimodal nonlinear optical imaging of unstained retinas in the epi-direction with a sub-40 fs Yb-fiber laser. Biomed Opt Express. 2017 Nov 01; 8(11):5228-5242. Murashova GA, Mancuso CA, Canfield JL, Sakami S, Palczewski K, Palczewska G, Dantus M. PMID: 29188116; PMCID: PMC5695966.
      View in: PubMed   Mentions: 7  
    103. Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors. Proc Natl Acad Sci U S A. 2017 11 07; 114(45):E9675-E9684. Kolesnikov AV, Orban T, Jin H, Brooks C, Hofmann L, Dong Z, Sokolov M, Palczewski K, Kefalov VJ. PMID: 29078372; PMCID: PMC5692576.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    104. Quantitative phosphoproteomics reveals involvement of multiple signaling pathways in early phagocytosis by the retinal pigmented epithelium. J Biol Chem. 2017 12 01; 292(48):19826-19839. Chiang CK, Tworak A, Kevany BM, Xu B, Mayne J, Ning Z, Figeys D, Palczewski K. PMID: 28978645; PMCID: PMC5712622.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    105. Designing Safer Analgesics via μ-Opioid Receptor Pathways. Trends Pharmacol Sci. 2017 11; 38(11):1016-1037. Chan HCS, McCarthy D, Li J, Palczewski K, Yuan S. PMID: 28935293; PMCID: PMC5690544.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    106. Towards Treatment of Stargardt Disease: Workshop Organized and Sponsored by the Foundation Fighting Blindness. Transl Vis Sci Technol. 2017 09; 6(5):6. Sears AE, Bernstein PS, Cideciyan AV, Hoyng C, Charbel Issa P, Palczewski K, Rosenfeld PJ, Sadda S, Schraermeyer U, Sparrow JR, Washington I, Scholl HPN. PMID: 28920007; PMCID: PMC5599228.
      View in: PubMed   Mentions: 27     Fields:    
    107. Crowd sourcing difficult problems in protein science. Protein Sci. 2017 Nov; 26(11):2118-2125. Alexander NS, Palczewski K. PMID: 28762619; PMCID: PMC5654861.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    108. Photoreceptor cells produce inflammatory products that contribute to retinal vascular permeability in a mouse model of diabetes. Diabetologia. 2017 10; 60(10):2111-2120. Tonade D, Liu H, Palczewski K, Kern TS. PMID: 28755268; PMCID: PMC5660634.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    109. The role of retinol dehydrogenase 10 in the cone visual cycle. Sci Rep. 2017 05 24; 7(1):2390. Xue Y, Sato S, Razafsky D, Sahu B, Shen SQ, Potter C, Sandell LL, Corbo JC, Palczewski K, Maeda A, Hodzic D, Kefalov VJ. PMID: 28539612; PMCID: PMC5443843.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    110. Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center. Biochemistry. 2017 06 06; 56(22):2836-2852. Sui X, Weitz AC, Farquhar ER, Badiee M, Banerjee S, von Lintig J, Tochtrop GP, Palczewski K, Hendrich MP, Kiser PD. PMID: 28493664; PMCID: PMC5541372.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    111. Complex binding pathways determine the regeneration of mammalian green cone opsin with a locked retinal analogue. J Biol Chem. 2017 06 30; 292(26):10983-10997. Alexander NS, Katayama K, Sun W, Salom D, Gulati S, Zhang J, Mogi M, Palczewski K, Jastrzebska B. PMID: 28487362; PMCID: PMC5491782.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    112. Rational Tuning of Visual Cycle Modulator Pharmacodynamics. J Pharmacol Exp Ther. 2017 07; 362(1):131-145. Kiser PD, Zhang J, Badiee M, Kinoshita J, Peachey NS, Tochtrop GP, Palczewski K. PMID: 28476927; PMCID: PMC5490204.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    113. Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors. Biochemistry. 2017 05 02; 56(17):2338-2348. Hofmann L, Alexander NS, Sun W, Zhang J, Orban T, Palczewski K. PMID: 28402104; PMCID: PMC5501310.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    114. Skunkworks project for Big Pharma. Pharmacol Res. 2017 Oct; 124:167-168. Palczewski K. PMID: 28363722; PMCID: PMC5596451.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    115. Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism. Proc Natl Acad Sci U S A. 2017 03 28; 114(13):E2608-E2615. Gulati S, Jastrzebska B, Banerjee S, Placeres ÁL, Miszta P, Gao S, Gunderson K, Tochtrop GP, Filipek S, Katayama K, Kiser PD, Mogi M, Stewart PL, Palczewski K. PMID: 28289214; PMCID: PMC5380078.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    116. Epi-direction detected multimodal imaging of an unstained mouse retina with a Yb-fiber laser. Proc SPIE Int Soc Opt Eng. 2017 Mar; 10069. Murashova GA, Mancuso CA, Sakami S, Palczewski K, Palczewska G, Dantus M. PMID: 28989217; PMCID: PMC5627661.
      View in: PubMed   Mentions: 1  
    117. Targeted Multifunctional Lipid ECO Plasmid DNA Nanoparticles as Efficient Non-viral Gene Therapy for Leber's Congenital Amaurosis. Mol Ther Nucleic Acids. 2017 Jun 16; 7:42-52. Sun D, Sahu B, Gao S, Schur RM, Vaidya AM, Maeda A, Palczewski K, Lu ZR. PMID: 28624218; PMCID: PMC5363681.
      View in: PubMed   Mentions: 23  
    118. MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice. J Biol Chem. 2017 02 24; 292(8):3366-3378. Sundermeier TR, Sakami S, Sahu B, Howell SJ, Gao S, Dong Z, Golczak M, Maeda A, Palczewski K. PMID: 28104803; PMCID: PMC5336169.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    119. Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration. Hum Mol Genet. 2017 01 15; 26(2):305-319. Athanasiou D, Aguila M, Opefi CA, South K, Bellingham J, Bevilacqua D, Munro PM, Kanuga N, Mackenzie FE, Dubis AM, Georgiadis A, Graca AB, Pearson RA, Ali RR, Sakami S, Palczewski K, Sherman MY, Reeves PJ, Cheetham ME. PMID: 28065882; PMCID: PMC5351934.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    120. Formation and Clearance of All-Trans-Retinol in Rods Investigated in the Living Primate Eye With Two-Photon Ophthalmoscopy. Invest Ophthalmol Vis Sci. 2017 01 01; 58(1):604-613. Sharma R, Schwarz C, Hunter JJ, Palczewska G, Palczewski K, Williams DR. PMID: 28129424; PMCID: PMC5283085.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    121. A G Protein-Coupled Receptor Dimerization Interface in Human Cone Opsins. Biochemistry. 2017 Jan 10; 56(1):61-72. Jastrzebska B, Comar WD, Kaliszewski MJ, Skinner KC, Torcasio MH, Esway AS, Jin H, Palczewski K, Smith AW. PMID: 28045251; PMCID: PMC5274527.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    122. Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family. Biochemistry. 2016 Nov 29; 55(47):6545-6557. Hofmann L, Tsybovsky Y, Alexander NS, Babino D, Leung NY, Montell C, Banerjee S, von Lintig J, Palczewski K. PMID: 27809489; PMCID: PMC5154250.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    123. Safety assessment in macaques of light exposures for functional two-photon ophthalmoscopy in humans. Biomed Opt Express. 2016 Dec 01; 7(12):5148-5169. Schwarz C, Sharma R, Fischer WS, Chung M, Palczewska G, Palczewski K, Williams DR, Hunter JJ. PMID: 28018732; PMCID: PMC5175559.
      View in: PubMed   Mentions: 16  
    124. Receptor MER Tyrosine Kinase Proto-oncogene (MERTK) Is Not Required for Transfer of Bis-retinoids to the Retinal Pigmented Epithelium. J Biol Chem. 2016 Dec 23; 291(52):26937-26949. Palczewska G, Maeda A, Golczak M, Arai E, Dong Z, Perusek L, Kevany B, Palczewski K. PMID: 27875314; PMCID: PMC5207201.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    125. Transcriptome profiling of NIH3T3 cell lines expressing opsin and the P23H opsin mutant identifies candidate drugs for the treatment of retinitis pigmentosa. Pharmacol Res. 2017 01; 115:1-13. Chen Y, Brooks MJ, Gieser L, Swaroop A, Palczewski K. PMID: 27838510; PMCID: PMC5205556.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    126. Transcriptome analysis reveals rod/cone photoreceptor specific signatures across mammalian retinas. Hum Mol Genet. 2016 10 15; 25(20):4376-4388. Mustafi D, Kevany BM, Bai X, Golczak M, Adams MD, Wynshaw-Boris A, Palczewski K. PMID: 28172828; PMCID: PMC6078599.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    127. Eyes on systems pharmacology. Pharmacol Res. 2016 Dec; 114:39-41. Chen Y, Kern TS, Kiser PD, Palczewski K. PMID: 27720767; PMCID: PMC5154905.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    128. Dynamic peptides of human TPP1 fulfill diverse functions in telomere maintenance. Nucleic Acids Res. 2016 Dec 01; 44(21):10467-10479. Rajavel M, Orban T, Xu M, Hernandez-Sanchez W, de la Fuente M, Palczewski K, Taylor DJ. PMID: 27655633; PMCID: PMC5137443.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    129. Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes. Invest Ophthalmol Vis Sci. 2016 08 01; 57(10):4272-81. Liu H, Tang J, Du Y, Saadane A, Tonade D, Samuels I, Veenstra A, Palczewski K, Kern TS. PMID: 27548901; PMCID: PMC5015983.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    130. The Molecular Mechanism of P2Y1 Receptor Activation. Angew Chem Int Ed Engl. 2016 08 22; 55(35):10331-5. Yuan S, Chan HC, Vogel H, Filipek S, Stevens RC, Palczewski K. PMID: 27460867; PMCID: PMC4996126.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    131. Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration. Sci Signal. 2016 07 26; 9(438):ra74. Chen Y, Palczewska G, Masuho I, Gao S, Jin H, Dong Z, Gieser L, Brooks MJ, Kiser PD, Kern TS, Martemyanov KA, Swaroop A, Palczewski K. PMID: 27460988; PMCID: PMC4972460.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    132. Key Residues for Catalytic Function and Metal Coordination in a Carotenoid Cleavage Dioxygenase. J Biol Chem. 2016 09 09; 291(37):19401-12. Sui X, Zhang J, Golczak M, Palczewski K, Kiser PD. PMID: 27453555; PMCID: PMC5016679.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    133. Retinoids and Retinal Diseases. Annu Rev Vis Sci. 2016 10; 2:197-234. Kiser PD, Palczewski K. PMID: 27917399; PMCID: PMC5132409.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimals
    134. Image registration and averaging of low laser power two-photon fluorescence images of mouse retina. Biomed Opt Express. 2016 Jul 01; 7(7):2671-91. Alexander NS, Palczewska G, Stremplewski P, Wojtkowski M, Kern TS, Palczewski K. PMID: 27446697; PMCID: PMC4948621.
      View in: PubMed   Mentions: 13  
    135. Mechanistic Studies on the Stereoselectivity of the Serotonin 5-HT1A Receptor. Angew Chem Int Ed Engl. 2016 07 18; 55(30):8661-5. Yuan S, Peng Q, Palczewski K, Vogel H, Filipek S. PMID: 27244650; PMCID: PMC4957245.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    136. Lecithin:Retinol Acyltransferase: A Key Enzyme Involved in the Retinoid (visual) Cycle. Biochemistry. 2016 Jun 07; 55(22):3082-91. Sears AE, Palczewski K. PMID: 27183166; PMCID: PMC5555363.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    137. Dominant and recessive mutations in rhodopsin activate different cell death pathways. Hum Mol Genet. 2016 07 01; 25(13):2801-2812. Comitato A, Di Salvo MT, Turchiano G, Montanari M, Sakami S, Palczewski K, Marigo V. PMID: 27149983.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    138. A small molecule mitigates hearing loss in a mouse model of Usher syndrome III. Nat Chem Biol. 2016 06; 12(6):444-51. Alagramam KN, Gopal SR, Geng R, Chen DH, Nemet I, Lee R, Tian G, Miyagi M, Malagu KF, Lock CJ, Esmieu WR, Owens AP, Lindsay NA, Ouwehand K, Albertus F, Fischer DF, Bürli RW, MacLeod AM, Harte WE, Palczewski K, Imanishi Y. PMID: 27110679; PMCID: PMC4871731.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    139. Conformational Change of Human Checkpoint Kinase 1 (Chk1) Induced by DNA Damage. J Biol Chem. 2016 Jun 17; 291(25):12951-9. Han X, Tang J, Wang J, Ren F, Zheng J, Gragg M, Kiser P, Park PS, Palczewski K, Yao X, Zhang Y. PMID: 27129240; PMCID: PMC4933214.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    140. An effective thiol-reactive probe for differential scanning fluorimetry with a standard real-time polymerase chain reaction device. Anal Biochem. 2016 Apr 15; 499:63-65. Hofmann L, Gulati S, Sears A, Stewart PL, Palczewski K. PMID: 26851339; PMCID: PMC4788517.
      View in: PubMed   Mentions: 13     Fields:    
    141. The Biochemical Basis of Vitamin A3 Production in Arthropod Vision. ACS Chem Biol. 2016 Apr 15; 11(4):1049-57. Babino D, Golczak M, Kiser PD, Wyss A, Palczewski K, von Lintig J. PMID: 26811964; PMCID: PMC4841470.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    142. Two-Photon Autofluorescence Imaging Reveals Cellular Structures Throughout the Retina of the Living Primate Eye. Invest Ophthalmol Vis Sci. 2016 Feb; 57(2):632-46. Sharma R, Williams DR, Palczewska G, Palczewski K, Hunter JJ. PMID: 26903224; PMCID: PMC4771181.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    143. In Vivo Two-Photon Fluorescence Kinetics of Primate Rods and Cones. Invest Ophthalmol Vis Sci. 2016 Feb; 57(2):647-57. Sharma R, Schwarz C, Williams DR, Palczewska G, Palczewski K, Hunter JJ. PMID: 26903225; PMCID: PMC4771186.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    144. Utilization of Dioxygen by Carotenoid Cleavage Oxygenases. J Biol Chem. 2015 Dec 18; 290(51):30212-23. Sui X, Golczak M, Zhang J, Kleinberg KA, von Lintig J, Palczewski K, Kiser PD. PMID: 26499794; PMCID: PMC4683246.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    145. Retinol dehydrogenase 8 and ATP-binding cassette transporter 4 modulate dark adaptation of M-cones in mammalian retina. J Physiol. 2015 Nov 15; 593(22):4923-41. Kolesnikov AV, Maeda A, Tang PH, Imanishi Y, Palczewski K, Kefalov VJ. PMID: 26350353; PMCID: PMC4650407.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    146. Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium. J Biol Chem. 2015 Nov 27; 290(48):29035-44. Perusek L, Sahu B, Parmar T, Maeno H, Arai E, Le YZ, Subauste CS, Chen Y, Palczewski K, Maeda A. PMID: 26468292; PMCID: PMC4661415.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    147. The impact of microRNA gene regulation on the survival and function of mature cell types in the eye. FASEB J. 2016 Jan; 30(1):23-33. Sundermeier TR, Palczewski K. PMID: 26399786; PMCID: PMC4684546.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    148. Conditional Ablation of Retinol Dehydrogenase 10 in the Retinal Pigmented Epithelium Causes Delayed Dark Adaption in Mice. J Biol Chem. 2015 Nov 06; 290(45):27239-27247. Sahu B, Sun W, Perusek L, Parmar V, Le YZ, Griswold MD, Palczewski K, Maeda A. PMID: 26391396; PMCID: PMC4646373.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    149. Disruption of Rhodopsin Dimerization with Synthetic Peptides Targeting an Interaction Interface. J Biol Chem. 2015 Oct 16; 290(42):25728-44. Jastrzebska B, Chen Y, Orban T, Jin H, Hofmann L, Palczewski K. PMID: 26330551; PMCID: PMC4646215.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    150. Periscope for noninvasive two-photon imaging of murine retina in vivo. Biomed Opt Express. 2015 Sep 01; 6(9):3352-61. Stremplewski P, Komar K, Palczewski K, Wojtkowski M, Palczewska G. PMID: 26417507; PMCID: PMC4574663.
      View in: PubMed   Mentions: 16  
    151. Self-Assembly of a Multifunctional Lipid With Core-Shell Dendrimer DNA Nanoparticles Enhanced Efficient Gene Delivery at Low Charge Ratios into RPE Cells. Macromol Biosci. 2015 Dec; 15(12):1663-72. Sun D, Maeno H, Gujrati M, Schur R, Maeda A, Maeda T, Palczewski K, Lu ZR. PMID: 26271011; PMCID: PMC4770799.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    152. Semi-automated discrimination of retinal pigmented epithelial cells in two-photon fluorescence images of mouse retinas. Biomed Opt Express. 2015 Aug 01; 6(8):3032-52. Alexander NS, Palczewska G, Palczewski K. PMID: 26309765; PMCID: PMC4541529.
      View in: PubMed   Mentions:
    153. Serum levels of lipid metabolites in age-related macular degeneration. FASEB J. 2015 Nov; 29(11):4579-88. Orban T, Johnson WM, Dong Z, Maeda T, Maeda A, Sakai T, Tsuneoka H, Mieyal JJ, Palczewski K. PMID: 26187344; PMCID: PMC4608905.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCTClinical Trials
    154. Advances in understanding the molecular basis of the first steps in color vision. Prog Retin Eye Res. 2015 Nov; 49:46-66. Hofmann L, Palczewski K. PMID: 26187035; PMCID: PMC4651776.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    155. Retinylamine Benefits Early Diabetic Retinopathy in Mice. J Biol Chem. 2015 Aug 28; 290(35):21568-79. Liu H, Tang J, Du Y, Lee CA, Golczak M, Muthusamy A, Antonetti DA, Veenstra AA, Amengual J, von Lintig J, Palczewski K, Kern TS. PMID: 26139608; PMCID: PMC4571881.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    156. Manganese-Enhanced MRI for Preclinical Evaluation of Retinal Degeneration Treatments. Invest Ophthalmol Vis Sci. 2015 Jul; 56(8):4936-42. Schur RM, Sheng L, Sahu B, Yu G, Gao S, Yu X, Maeda A, Palczewski K, Lu ZR. PMID: 26225634; PMCID: PMC4525634.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    157. Molecular pharmacodynamics of emixustat in protection against retinal degeneration. J Clin Invest. 2015 Jul 01; 125(7):2781-94. Zhang J, Kiser PD, Badiee M, Palczewska G, Dong Z, Golczak M, Tochtrop GP, Palczewski K. PMID: 26075817; PMCID: PMC4563688.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    158. The mechanism of ligand-induced activation or inhibition of μ- and κ-opioid receptors. Angew Chem Int Ed Engl. 2015 Jun 22; 54(26):7560-3. Yuan S, Palczewski K, Peng Q, Kolinski M, Vogel H, Filipek S. PMID: 25968837.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    159. Improvement in vision: a new goal for treatment of hereditary retinal degenerations. Expert Opin Orphan Drugs. 2015 May 04; 3(5):563-575. Jacobson SG, Cideciyan AV, Aguirre GD, Roman AJ, Sumaroka A, Hauswirth WW, Palczewski K. PMID: 26246977; PMCID: PMC4487613.
      View in: PubMed   Mentions: 15  
    160. Catalytic mechanism of a retinoid isomerase essential for vertebrate vision. Nat Chem Biol. 2015 Jun; 11(6):409-15. Kiser PD, Zhang J, Badiee M, Li Q, Shi W, Sui X, Golczak M, Tochtrop GP, Palczewski K. PMID: 25894083; PMCID: PMC4433804.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    161. A High-Throughput Drug Screening Strategy for Detecting Rhodopsin P23H Mutant Rescue and Degradation. Invest Ophthalmol Vis Sci. 2015 Apr; 56(4):2553-67. Chen Y, Tang H, Seibel W, Papoian R, Li X, Lambert NA, Palczewski K. PMID: 25783607; PMCID: PMC4554260.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    162. Systems Pharmacology Links GPCRs with Retinal Degenerative Disorders. Annu Rev Pharmacol Toxicol. 2016; 56:273-98. Chen Y, Palczewski K. PMID: 25839098; PMCID: PMC4580525.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    163. Crystallization of proteins from crude bovine rod outer segments. Methods Enzymol. 2015; 557:439-58. Baker BY, Gulati S, Shi W, Wang B, Stewart PL, Palczewski K. PMID: 25950977; PMCID: PMC4486017.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    164. Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations. Hum Mol Genet. 2015 Jun 01; 24(11):3220-37. Zhang N, Tsybovsky Y, Kolesnikov AV, Rozanowska M, Swider M, Schwartz SB, Stone EM, Palczewska G, Maeda A, Kefalov VJ, Jacobson SG, Cideciyan AV, Palczewski K. PMID: 25712131; PMCID: PMC4424957.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    165. Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability. FASEB J. 2015 May; 29(5):2194-204. Du Y, Cramer M, Lee CA, Tang J, Muthusamy A, Antonetti DA, Jin H, Palczewski K, Kern TS. PMID: 25667222; PMCID: PMC4415023.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    166. Animals deficient in C2Orf71, an autosomal recessive retinitis pigmentosa-associated locus, develop severe early-onset retinal degeneration. Hum Mol Genet. 2015 May 01; 24(9):2627-40. Kevany BM, Zhang N, Jastrzebska B, Palczewski K. PMID: 25616964; PMCID: PMC4383867.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    167. Prolonged prevention of retinal degeneration with retinylamine loaded nanoparticles. Biomaterials. 2015 Mar; 44:103-10. Puntel A, Maeda A, Golczak M, Gao SQ, Yu G, Palczewski K, Lu ZR. PMID: 25617130; PMCID: PMC4393824.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    168. The G protein-coupled receptor rhodopsin: a historical perspective. Methods Mol Biol. 2015; 1271:3-18. Hofmann L, Palczewski K. PMID: 25697513; PMCID: PMC4593475.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    169. Expansion of first-in-class drug candidates that sequester toxic all-trans-retinal and prevent light-induced retinal degeneration. Mol Pharmacol. 2015; 87(3):477-91. Zhang J, Dong Z, Mundla SR, Hu XE, Seibel W, Papoian R, Palczewski K, Golczak M. PMID: 25538117; PMCID: PMC4352584.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    170. Serial block face-scanning electron microscopy: a method to study retinal degenerative phenotypes. Curr Protoc Mouse Biol. 2014 Dec 11; 4(4):197-204. Mustafi D, Kikano S, Palczewski K. PMID: 25621191; PMCID: PMC4303034.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    171. Human infrared vision is triggered by two-photon chromophore isomerization. Proc Natl Acad Sci U S A. 2014 Dec 16; 111(50):E5445-54. Palczewska G, Vinberg F, Stremplewski P, Bircher MP, Salom D, Komar K, Zhang J, Cascella M, Wojtkowski M, Kefalov VJ, Palczewski K. PMID: 25453064; PMCID: PMC4273384.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    172. Multifunctional PEG retinylamine conjugate provides prolonged protection against retinal degeneration in mice. Biomacromolecules. 2014 Dec 08; 15(12):4570-8. Yu G, Wu X, Ayat N, Maeda A, Gao SQ, Golczak M, Palczewski K, Lu ZR. PMID: 25390360; PMCID: PMC4261990.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    173. Isotopic labeling of mammalian G protein-coupled receptors heterologously expressed in Caenorhabditis elegans. Anal Biochem. 2015 Mar 01; 472:30-6. Salom D, Cao P, Yuan Y, Miyagi M, Feng Z, Palczewski K. PMID: 25461480; PMCID: PMC4322386.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    174. LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3. Nat Chem Biol. 2015 Jan; 11(1):26-32. Golczak M, Sears AE, Kiser PD, Palczewski K. PMID: 25383759; PMCID: PMC4270908.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    175. Chemistry and biology of the initial steps in vision: the Friedenwald lecture. Invest Ophthalmol Vis Sci. 2014 Oct 22; 55(10):6651-72. Palczewski K. PMID: 25338686; PMCID: PMC4207101.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    176. Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration. Mol Neurobiol. 2015 Aug; 52(1):679-95. Chiang WC, Kroeger H, Sakami S, Messah C, Yasumura D, Matthes MT, Coppinger JA, Palczewski K, LaVail MM, Lin JH. PMID: 25270370; PMCID: PMC4383737.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    177. High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules. Protein Sci. 2014 Nov; 23(11):1629-39. Baker BY, Shi W, Wang B, Palczewski K. PMID: 25176140; PMCID: PMC4241113.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    178. Structural insights into activation of the retinal L-type Ca²⁺ channel (Cav1.4) by Ca²⁺-binding protein 4 (CaBP4). J Biol Chem. 2014 Nov 07; 289(45):31262-73. Park S, Li C, Haeseleer F, Palczewski K, Ames JB. PMID: 25258313; PMCID: PMC4223327.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    179. Argonaute high-throughput sequencing of RNAs isolated by cross-linking immunoprecipitation reveals a snapshot of miRNA gene regulation in the mammalian retina. Biochemistry. 2014 Sep 23; 53(37):5831-3. Sundermeier TR, Jin H, Kleinjan ML, Mustafi D, Licatalosi DD, Palczewski K. PMID: 25204418; PMCID: PMC4172207.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    180. Activation of G-protein-coupled receptors correlates with the formation of a continuous internal water pathway. Nat Commun. 2014 Sep 09; 5:4733. Yuan S, Filipek S, Palczewski K, Vogel H. PMID: 25203160.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCells
    181. Endogenous fluorophores enable two-photon imaging of the primate eye. Invest Ophthalmol Vis Sci. 2014 Jun 26; 55(7):4438-47. Palczewska G, Golczak M, Williams DR, Hunter JJ, Palczewski K. PMID: 24970255; PMCID: PMC4106253.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    182. Noninvasive two-photon microscopy imaging of mouse retina and retinal pigment epithelium through the pupil of the eye. Nat Med. 2014 Jul; 20(7):785-9. Palczewska G, Dong Z, Golczak M, Hunter JJ, Williams DR, Alexander NS, Palczewski K. PMID: 24952647; PMCID: PMC4087080.
      View in: PubMed   Mentions: 55     Fields:    Translation:Animals
    183. Identification and characterization of novel inhibitors of Mammalian aspartyl aminopeptidase. Mol Pharmacol. 2014 Aug; 86(2):231-42. Chen Y, Tang H, Seibel W, Papoian R, Oh K, Li X, Zhang J, Golczak M, Palczewski K, Kiser PD. PMID: 24913940; PMCID: PMC4127928.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    184. Time-resolved fluorescence spectroscopy measures clustering and mobility of a G protein-coupled receptor opsin in live cell membranes. J Am Chem Soc. 2014 Jun 11; 136(23):8342-9. Comar WD, Schubert SM, Jastrzebska B, Palczewski K, Smith AW. PMID: 24831851; PMCID: PMC4063175.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    185. STRA6 is critical for cellular vitamin A uptake and homeostasis. Hum Mol Genet. 2014 Oct 15; 23(20):5402-17. Amengual J, Zhang N, Kemerer M, Maeda T, Palczewski K, Von Lintig J. PMID: 24852372; PMCID: PMC4168826.
      View in: PubMed   Mentions: 70     Fields:    Translation:Animals
    186. DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice. FASEB J. 2014 Aug; 28(8):3780-91. Sundermeier TR, Zhang N, Vinberg F, Mustafi D, Kohno H, Golczak M, Bai X, Maeda A, Kefalov VJ, Palczewski K. PMID: 24812086; PMCID: PMC4101655.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    187. Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice. Proc Natl Acad Sci U S A. 2014 Apr 08; 111(14):E1428-37. Maeda A, Palczewska G, Golczak M, Kohno H, Dong Z, Maeda T, Palczewski K. PMID: 24706832; PMCID: PMC3986171.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    188. Analysis of carotenoid isomerase activity in a prototypical carotenoid cleavage enzyme, apocarotenoid oxygenase (ACO). J Biol Chem. 2014 May 02; 289(18):12286-99. Sui X, Kiser PD, Che T, Carey PR, Golczak M, Shi W, von Lintig J, Palczewski K. PMID: 24648526; PMCID: PMC4007427.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    189. R9AP overexpression alters phototransduction kinetics in iCre75 mice. Invest Ophthalmol Vis Sci. 2014 Mar 06; 55(3):1339-47. Sundermeier TR, Vinberg F, Mustafi D, Bai X, Kefalov VJ, Palczewski K. PMID: 24526444; PMCID: PMC3945901.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    190. Expression, purification and structural properties of ABC transporter ABCA4 and its individual domains. Protein Expr Purif. 2014 May; 97:50-60. Tsybovsky Y, Palczewski K. PMID: 24583180; PMCID: PMC4033903.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    191. Reliable determination of site-specific in vivo protein N-glycosylation based on collision-induced MS/MS and chromatographic retention time. J Am Soc Mass Spectrom. 2014 May; 25(5):729-41. Wang B, Tsybovsky Y, Palczewski K, Chance MR. PMID: 24549892; PMCID: PMC3988243.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    192. The macular degeneration-linked C1QTNF5 (S163) mutation causes higher-order structural rearrangements. J Struct Biol. 2014 Apr; 186(1):86-94. Tu X, Palczewski K. PMID: 24531000; PMCID: PMC3993933.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    193. Inherent instability of the retinitis pigmentosa P23H mutant opsin. J Biol Chem. 2014 Mar 28; 289(13):9288-303. Chen Y, Jastrzebska B, Cao P, Zhang J, Wang B, Sun W, Yuan Y, Feng Z, Palczewski K. PMID: 24515108; PMCID: PMC3979360.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    194. Human cellular retinaldehyde-binding protein has secondary thermal 9-cis-retinal isomerase activity. J Am Chem Soc. 2014 Jan 08; 136(1):137-46. Bolze CS, Helbling RE, Owen RL, Pearson AR, Pompidor G, Dworkowski F, Fuchs MR, Furrer J, Golczak M, Palczewski K, Cascella M, Stocker A. PMID: 24328211; PMCID: PMC3936205.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    195. Synthesis and evaluation of a nanoglobular dendrimer 5-aminosalicylic Acid conjugate with a hydrolyzable schiff base spacer for treating retinal degeneration. ACS Nano. 2014 Jan 28; 8(1):153-61. Wu X, Yu G, Luo C, Maeda A, Zhang N, Sun D, Zhou Z, Puntel A, Palczewski K, Lu ZR. PMID: 24350906; PMCID: PMC4060971.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    196. Structural approaches to understanding retinal proteins needed for vision. Curr Opin Cell Biol. 2014 Apr; 27:32-43. Orban T, Jastrzebska B, Palczewski K. PMID: 24680428; PMCID: PMC3971393.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    197. Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration. J Clin Invest. 2013 Dec; 123(12):5119-34. Chen Y, Palczewska G, Mustafi D, Golczak M, Dong Z, Sawada O, Maeda T, Maeda A, Palczewski K. PMID: 24231350; PMCID: PMC3859412.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    198. P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis. Hum Mol Genet. 2014 Apr 01; 23(7):1723-41. Sakami S, Kolesnikov AV, Kefalov VJ, Palczewski K. PMID: 24214395; PMCID: PMC3943518.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    199. Structural and functional analysis of the native peripherin-ROM1 complex isolated from photoreceptor cells. J Biol Chem. 2013 Dec 20; 288(51):36272-84. Kevany BM, Tsybovsky Y, Campuzano ID, Schnier PD, Engel A, Palczewski K. PMID: 24196967; PMCID: PMC3868743.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    200. Retinal pigmented epithelial cells obtained from human induced pluripotent stem cells possess functional visual cycle enzymes in vitro and in vivo. J Biol Chem. 2013 Nov 29; 288(48):34484-93. Maeda T, Lee MJ, Palczewska G, Marsili S, Tesar PJ, Palczewski K, Takahashi M, Maeda A. PMID: 24129572; PMCID: PMC3843063.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    201. Two carotenoid oxygenases contribute to mammalian provitamin A metabolism. J Biol Chem. 2013 Nov 22; 288(47):34081-34096. Amengual J, Widjaja-Adhi MAK, Rodriguez-Santiago S, Hessel S, Golczak M, Palczewski K, von Lintig J. PMID: 24106281; PMCID: PMC3837149.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    202. Photoreceptor cells are major contributors to diabetes-induced oxidative stress and local inflammation in the retina. Proc Natl Acad Sci U S A. 2013 Oct 08; 110(41):16586-91. Du Y, Veenstra A, Palczewski K, Kern TS. PMID: 24067647; PMCID: PMC3799310.
      View in: PubMed   Mentions: 194     Fields:    Translation:AnimalsCells
    203. Cellular retinaldehyde binding protein-different binding modes and micro-solvation patterns for high-affinity 9-cis- and 11-cis-retinal substrates. J Phys Chem B. 2013 Sep 19; 117(37):10719-29. Helbling RE, Bolze CS, Golczak M, Palczewski K, Stocker A, Cascella M. PMID: 23964907.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    204. Photoreceptor phagocytosis is mediated by phosphoinositide signaling. FASEB J. 2013 Nov; 27(11):4585-95. Mustafi D, Kevany BM, Genoud C, Bai X, Palczewski K. PMID: 23913857; PMCID: PMC3804748.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    205. Chemistry of the retinoid (visual) cycle. Chem Rev. 2014 Jan 08; 114(1):194-232. Kiser PD, Golczak M, Palczewski K. PMID: 23905688; PMCID: PMC3858459.
      View in: PubMed   Mentions: 163     Fields:    Translation:HumansAnimalsCells
    206. In vivo two-photon imaging of the mouse retina. Biomed Opt Express. 2013; 4(8):1285-93. Sharma R, Yin L, Geng Y, Merigan WH, Palczewska G, Palczewski K, Williams DR, Hunter JJ. PMID: 24009992; PMCID: PMC3756587.
      View in: PubMed   Mentions: 38  
    207. Structural basis of carotenoid cleavage: from bacteria to mammals. Arch Biochem Biophys. 2013 Nov 15; 539(2):203-13. Sui X, Kiser PD, Lintig Jv, Palczewski K. PMID: 23827316; PMCID: PMC3818509.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    208. Characterization of human β,β-carotene-15,15'-monooxygenase (BCMO1) as a soluble monomeric enzyme. Arch Biochem Biophys. 2013 Nov 15; 539(2):214-22. Kowatz T, Babino D, Kiser P, Palczewski K, von Lintig J. PMID: 23727499; PMCID: PMC3795993.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    209. From atomic structures to neuronal functions of g protein-coupled receptors. Annu Rev Neurosci. 2013 Jul 08; 36:139-64. Palczewski K, Orban T. PMID: 23682660; PMCID: PMC4594856.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    210. Biochemistry. As good as chocolate. Science. 2013 May 03; 340(6132):562-3. Palczewski K, Kiser PD. PMID: 23641106; PMCID: PMC4596528.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    211. Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal. J Biol Chem. 2013 May 24; 288(21):15326-41. Kohno H, Chen Y, Kevany BM, Pearlman E, Miyagi M, Maeda T, Palczewski K, Maeda A. PMID: 23572532; PMCID: PMC3663552.
      View in: PubMed   Mentions: 101     Fields:    Translation:AnimalsCells
    212. Molecular organization and ATP-induced conformational changes of ABCA4, the photoreceptor-specific ABC transporter. Structure. 2013 May 07; 21(5):854-60. Tsybovsky Y, Orban T, Molday RS, Taylor D, Palczewski K. PMID: 23562398; PMCID: PMC3654078.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    213. Evolutionarily conserved long intergenic non-coding RNAs in the eye. Hum Mol Genet. 2013 Aug 01; 22(15):2992-3002. Mustafi D, Kevany BM, Bai X, Maeda T, Sears JE, Khalil AM, Palczewski K. PMID: 23562822; PMCID: PMC3699063.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    214. Light-induced translocation of RGS9-1 and Gβ5L in mouse rod photoreceptors. PLoS One. 2013; 8(3):e58832. Tian M, Zallocchi M, Wang W, Chen CK, Palczewski K, Delimont D, Cosgrove D, Peng YW. PMID: 23555598; PMCID: PMC3610756.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    215. The rhodopsin-transducin complex houses two distinct rhodopsin molecules. J Struct Biol. 2013 May; 182(2):164-72. Jastrzebska B, Ringler P, Palczewski K, Engel A. PMID: 23458690; PMCID: PMC3633645.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    216. Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection. J Biol Chem. 2013 Apr 12; 288(15):10406-17. Yan J, Kaur S, DeLucia M, Hao C, Mehrens J, Wang C, Golczak M, Palczewski K, Gronenborn AM, Ahn J, Skowronski J. PMID: 23426366; PMCID: PMC3624423.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    217. A hybrid structural approach to analyze ligand binding by the serotonin type 4 receptor (5-HT4). Mol Cell Proteomics. 2013 May; 12(5):1259-71. Padayatti PS, Wang L, Gupta S, Orban T, Sun W, Salom D, Jordan SR, Palczewski K, Chance MR. PMID: 23378516; PMCID: PMC3650337.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    218. QLT091001, a 9-cis-retinal analog, is well-tolerated by retinas of mice with impaired visual cycles. Invest Ophthalmol Vis Sci. 2013 Jan 17; 54(1):455-66. Maeda T, Dong Z, Jin H, Sawada O, Gao S, Utkhede D, Monk W, Palczewska G, Palczewski K. PMID: 23249702; PMCID: PMC4686220.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    219. Asymmetry of the rhodopsin dimer in complex with transducin. FASEB J. 2013 Apr; 27(4):1572-84. Jastrzebska B, Orban T, Golczak M, Engel A, Palczewski K. PMID: 23303210; PMCID: PMC3606538.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    220. Crystallization of G protein-coupled receptors. Methods Cell Biol. 2013; 117:451-68. Salom D, Padayatti PS, Palczewski K. PMID: 24143992; PMCID: PMC4605854.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    221. Expression of mammalian G protein-coupled receptors in Caenorhabditis elegans. Methods Enzymol. 2013; 520:239-56. Jastrzebska B, Salom D, Jin H, Cao P, Sun W, Palczewski K, Feng Z. PMID: 23332703; PMCID: PMC4112963.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    222. Retinal degeneration in animal models with a defective visual cycle. Drug Discov Today Dis Models. 2013; 10(4):e163-e172. Maeda A, Palczewski K. PMID: 25210527; PMCID: PMC4157753.
      View in: PubMed   Mentions: 12  
    223. 3D imaging and quantitative analysis of small solubilized membrane proteins and their complexes by transmission electron microscopy. Microscopy (Oxf). 2013 Feb; 62(1):95-107. Vahedi-Faridi A, Jastrzebska B, Palczewski K, Engel A. PMID: 23267047; PMCID: PMC3582345.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    224. G protein-coupled receptors--recent advances. Acta Biochim Pol. 2012; 59(4):515-29. Latek D, Modzelewska A, Trzaskowski B, Palczewski K, Filipek S. PMID: 23251911; PMCID: PMC4322417.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    225. Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization. J Clin Invest. 2013 Jan; 123(1):121-37. Zhang N, Kolesnikov AV, Jastrzebska B, Mustafi D, Sawada O, Maeda T, Genoud C, Engel A, Kefalov VJ, Palczewski K. PMID: 23221340; PMCID: PMC3533307.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    226. Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis. Proc Natl Acad Sci U S A. 2012 Oct 09; 109(41):E2747-56. Kiser PD, Farquhar ER, Shi W, Sui X, Chance MR, Palczewski K. PMID: 23012475; PMCID: PMC3478654.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    227. A microparticle/hydrogel combination drug-delivery system for sustained release of retinoids. Invest Ophthalmol Vis Sci. 2012 Sep 19; 53(10):6314-23. Gao SQ, Maeda T, Okano K, Palczewski K. PMID: 22918645; PMCID: PMC3465014.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    228. Crystal structure of the globular domain of C1QTNF5: Implications for late-onset retinal macular degeneration. J Struct Biol. 2012 Dec; 180(3):439-46. Tu X, Palczewski K. PMID: 22892318; PMCID: PMC3496058.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    229. Inflammatory priming predisposes mice to age-related retinal degeneration. J Clin Invest. 2012 Aug; 122(8):2989-3001. Mustafi D, Maeda T, Kohno H, Nadeau JH, Palczewski K. PMID: 22797304; PMCID: PMC3408755.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    230. HIV-1 reverse transcriptase (RT) polymorphism 172K suppresses the effect of clinically relevant drug resistance mutations to both nucleoside and non-nucleoside RT inhibitors. J Biol Chem. 2012 Aug 24; 287(35):29988-99. Hachiya A, Marchand B, Kirby KA, Michailidis E, Tu X, Palczewski K, Ong YT, Li Z, Griffin DT, Schuckmann MM, Tanuma J, Oka S, Singh K, Kodama EN, Sarafianos SG. PMID: 22761416; PMCID: PMC3436141.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    231. Lecithin:retinol acyltransferase is critical for cellular uptake of vitamin A from serum retinol-binding protein. J Biol Chem. 2012 Jul 13; 287(29):24216-27. Amengual J, Golczak M, Palczewski K, von Lintig J. PMID: 22637576; PMCID: PMC3397848.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    232. Structural basis for the acyltransferase activity of lecithin:retinol acyltransferase-like proteins. J Biol Chem. 2012 Jul 06; 287(28):23790-807. Golczak M, Kiser PD, Sears AE, Lodowski DT, Blaner WS, Palczewski K. PMID: 22605381; PMCID: PMC3390653.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    233. Conformational dynamics of activation for the pentameric complex of dimeric G protein-coupled receptor and heterotrimeric G protein. Structure. 2012 May 09; 20(5):826-40. Orban T, Jastrzebska B, Gupta S, Wang B, Miyagi M, Chance MR, Palczewski K. PMID: 22579250; PMCID: PMC3351692.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    234. Melanopsin is highly resistant to light and chemical bleaching in vivo. J Biol Chem. 2012 Jun 15; 287(25):20888-97. Sexton TJ, Golczak M, Palczewski K, Van Gelder RN. PMID: 22547062; PMCID: PMC3375512.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    235. Substrate-induced changes in the dynamics of rhodopsin kinase (G protein-coupled receptor kinase 1). Biochemistry. 2012 Apr 24; 51(16):3404-11. Orban T, Huang CC, Homan KT, Jastrzebska B, Tesmer JJ, Palczewski K. PMID: 22480180; PMCID: PMC3422436.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    236. The physiological impact of microRNA gene regulation in the retina. Cell Mol Life Sci. 2012 Aug; 69(16):2739-50. Sundermeier TR, Palczewski K. PMID: 22460583; PMCID: PMC3443797.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    237. Insights into substrate specificity and metal activation of mammalian tetrahedral aspartyl aminopeptidase. J Biol Chem. 2012 Apr 13; 287(16):13356-70. Chen Y, Farquhar ER, Chance MR, Palczewski K, Kiser PD. PMID: 22356908; PMCID: PMC3339940.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    238. Imaging of protein crystals with two-photon microscopy. Biochemistry. 2012 Feb 28; 51(8):1625-37. Padayatti P, Palczewska G, Sun W, Palczewski K, Salom D. PMID: 22324807; PMCID: PMC3293215.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    239. Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light-induced damage. J Neurochem. 2012 Apr; 121(1):146-56. Okano K, Maeda A, Chen Y, Chauhan V, Tang J, Palczewska G, Sakai T, Tsuneoka H, Palczewski K, Maeda T. PMID: 22220722; PMCID: PMC3303932.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    240. Primary amines protect against retinal degeneration in mouse models of retinopathies. Nat Chem Biol. 2011 Dec 25; 8(2):170-8. Maeda A, Golczak M, Chen Y, Okano K, Kohno H, Shiose S, Ishikawa K, Harte W, Palczewska G, Maeda T, Palczewski K. PMID: 22198730; PMCID: PMC3518042.
      View in: PubMed   Mentions: 93     Fields:    Translation:Animals
    241. Post-translational modifications of the serotonin type 4 receptor heterologously expressed in mouse rod cells. Biochemistry. 2012 Jan 10; 51(1):214-24. Salom D, Wang B, Dong Z, Sun W, Padayatti P, Jordan S, Salon JA, Palczewski K. PMID: 22145929; PMCID: PMC3268512.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    242. Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration. J Biol Chem. 2012 Feb 10; 287(7):5059-69. Chen Y, Okano K, Maeda T, Chauhan V, Golczak M, Maeda A, Palczewski K. PMID: 22184108; PMCID: PMC3281612.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansAnimalsCells
    243. The significance of G protein-coupled receptor crystallography for drug discovery. Pharmacol Rev. 2011 Dec; 63(4):901-37. Salon JA, Lodowski DT, Palczewski K. PMID: 21969326; PMCID: PMC3186081.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    244. Heterologous expression of functional G-protein-coupled receptors in Caenorhabditis elegans. FASEB J. 2012 Feb; 26(2):492-502. Salom D, Cao P, Sun W, Kramp K, Jastrzebska B, Jin H, Feng Z, Palczewski K. PMID: 22090314; PMCID: PMC3290431.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    245. Light-sensitive coupling of rhodopsin and melanopsin to G(i/o) and G(q) signal transduction in Caenorhabditis elegans. FASEB J. 2012 Feb; 26(2):480-91. Cao P, Sun W, Kramp K, Zheng M, Salom D, Jastrzebska B, Jin H, Palczewski K, Feng Z. PMID: 22090313; PMCID: PMC3290438.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    246. Thematic minireview series on focus on vision. J Biol Chem. 2012 Jan 13; 287(3):1610-1. Palczewski K. PMID: 22074916; PMCID: PMC3265840.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    247. Chemistry and biology of vision. J Biol Chem. 2012 Jan 13; 287(3):1612-9. Palczewski K. PMID: 22074921; PMCID: PMC3265841.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimalsCells
    248. Detergents stabilize the conformation of phosphodiesterase 6. Biochemistry. 2011 Nov 08; 50(44):9520-31. Baker BY, Palczewski K. PMID: 21978030; PMCID: PMC3215081.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    249. Rhodopsin-transducin heteropentamer: three-dimensional structure and biochemical characterization. J Struct Biol. 2011 Dec; 176(3):387-94. Jastrzebska B, Ringler P, Lodowski DT, Moiseenkova-Bell V, Golczak M, Müller SA, Palczewski K, Engel A. PMID: 21925606; PMCID: PMC3210324.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    250. Dietary 9-cis-β,β-carotene fails to rescue vision in mouse models of leber congenital amaurosis. Mol Pharmacol. 2011 Nov; 80(5):943-52. Maeda T, Perusek L, Amengual J, Babino D, Palczewski K, von Lintig J. PMID: 21862692; PMCID: PMC3198919.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    251. Sponge transgenic mouse model reveals important roles for the microRNA-183 (miR-183)/96/182 cluster in postmitotic photoreceptors of the retina. J Biol Chem. 2011 Sep 09; 286(36):31749-60. Zhu Q, Sun W, Okano K, Chen Y, Zhang N, Maeda T, Palczewski K. PMID: 21768104; PMCID: PMC3173082.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    252. Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4. Biochemistry. 2011 Aug 16; 50(32):6855-66. Tsybovsky Y, Wang B, Quazi F, Molday RS, Palczewski K. PMID: 21721517; PMCID: PMC3206228.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    253. Defective photoreceptor phagocytosis in a mouse model of enhanced S-cone syndrome causes progressive retinal degeneration. FASEB J. 2011 Sep; 25(9):3157-76. Mustafi D, Kevany BM, Genoud C, Okano K, Cideciyan AV, Sumaroka A, Roman AJ, Jacobson SG, Engel A, Adams MD, Palczewski K. PMID: 21659555; PMCID: PMC3157681.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    254. Enzymatic properties and regulation of the native isozymes of retinal membrane guanylyl cyclase (RetGC) from mouse photoreceptors. Biochemistry. 2011 Jun 28; 50(25):5590-600. Peshenko IV, Olshevskaya EV, Savchenko AB, Karan S, Palczewski K, Baehr W, Dizhoor AM. PMID: 21598940; PMCID: PMC3127287.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    255. Heterogeneous N-terminal acylation of retinal proteins results from the retina's unusual lipid metabolism. Biochemistry. 2011 May 10; 50(18):3764-76. Bereta G, Palczewski K. PMID: 21449552; PMCID: PMC3086940.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    256. Key enzymes of the retinoid (visual) cycle in vertebrate retina. Biochim Biophys Acta. 2012 Jan; 1821(1):137-51. Kiser PD, Golczak M, Maeda A, Palczewski K. PMID: 21447403; PMCID: PMC3158816.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    257. Role of bulk water in hydrolysis of the rhodopsin chromophore. J Biol Chem. 2011 May 27; 286(21):18930-7. Jastrzebska B, Palczewski K, Golczak M. PMID: 21460218; PMCID: PMC3099708.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    258. Retinyl ester storage particles (retinosomes) from the retinal pigmented epithelium resemble lipid droplets in other tissues. J Biol Chem. 2011 May 13; 286(19):17248-58. Orban T, Palczewska G, Palczewski K. PMID: 21454509; PMCID: PMC3089567.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    259. Serial sectioning for examination of photoreceptor cell architecture by focused ion beam technology. J Neurosci Methods. 2011 May 15; 198(1):70-6. Mustafi D, Avishai A, Avishai N, Engel A, Heuer A, Palczewski K. PMID: 21439323; PMCID: PMC3090522.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    260. Role of membrane integrity on G protein-coupled receptors: Rhodopsin stability and function. Prog Lipid Res. 2011 Jul; 50(3):267-77. Jastrzebska B, Debinski A, Filipek S, Palczewski K. PMID: 21435354; PMCID: PMC3114187.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    261. Toll-like receptor 3 is required for development of retinopathy caused by impaired all-trans-retinal clearance in mice. J Biol Chem. 2011 Apr 29; 286(17):15543-55. Shiose S, Chen Y, Okano K, Roy S, Kohno H, Tang J, Pearlman E, Maeda T, Palczewski K, Maeda A. PMID: 21383019; PMCID: PMC3083179.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    262. Activation of G protein-coupled receptor kinase 1 involves interactions between its N-terminal region and its kinase domain. Biochemistry. 2011 Mar 22; 50(11):1940-9. Huang CC, Orban T, Jastrzebska B, Palczewski K, Tesmer JJ. PMID: 21265573; PMCID: PMC3069497.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    263. Focus on vision: 3 decades of remarkable contributions to biology and medicine. FASEB J. 2011 Feb; 25(2):439-43. Palczewski K. PMID: 21282210; PMCID: PMC3228347.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    264. Probing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations. J Biol Chem. 2011 Mar 25; 286(12):10551-67. Sakami S, Maeda T, Bereta G, Okano K, Golczak M, Sumaroka A, Roman AJ, Cideciyan AV, Jacobson SG, Palczewski K. PMID: 21224384; PMCID: PMC3060508.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansAnimalsCells
    265. Images of photoreceptors in living primate eyes using adaptive optics two-photon ophthalmoscopy. Biomed Opt Express. 2010 Dec 17; 2(1):139-48. Hunter JJ, Masella B, Dubra A, Sharma R, Yin L, Merigan WH, Palczewska G, Palczewski K, Williams DR. PMID: 21326644; PMCID: PMC3028489.
      View in: PubMed   Mentions: 64  
    266. Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1. J Biol Chem. 2011 Feb 18; 286(7):5607-13. Mast N, Annalora AJ, Lodowski DT, Palczewski K, Stout CD, Pikuleva IA. PMID: 21159775; PMCID: PMC3037674.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    267. A mitochondrial enzyme degrades carotenoids and protects against oxidative stress. FASEB J. 2011 Mar; 25(3):948-59. Amengual J, Lobo GP, Golczak M, Li HN, Klimova T, Hoppel CL, Wyss A, Palczewski K, von Lintig J. PMID: 21106934; PMCID: PMC3042841.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    268. Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes. Nat Med. 2010 Dec; 16(12):1444-9. Palczewska G, Maeda T, Imanishi Y, Sun W, Chen Y, Williams DR, Piston DW, Maeda A, Palczewski K. PMID: 21076393; PMCID: PMC3057900.
      View in: PubMed   Mentions: 52     Fields:    Translation:Animals
    269. Blind dogs that can see: pharmacological treatment of Leber congenital amaurosis caused by a defective visual cycle. Arch Ophthalmol. 2010 Nov; 128(11):1483-5. Palczewski K. PMID: 21060052; PMCID: PMC4495581.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    270. Conformational changes in the g protein-coupled receptor rhodopsin revealed by histidine hydrogen-deuterium exchange. Biochemistry. 2010 Nov 09; 49(44):9425-7. Lodowski DT, Palczewski K, Miyagi M. PMID: 20939497; PMCID: PMC3075965.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    271. Vitamin A deficiency results in meiotic failure and accumulation of undifferentiated spermatogonia in prepubertal mouse testis. Biol Reprod. 2011 Feb; 84(2):336-41. Li H, Palczewski K, Baehr W, Clagett-Dame M. PMID: 20881313; PMCID: PMC3071267.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    272. Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology. 2010 Dec; 20(12):1643-53. Huang J, Xu Z, Wang D, Ogata CM, Palczewski K, Lee X, Young NM. PMID: 20826825; PMCID: PMC3003548.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    273. Electrostatic compensation restores trafficking of the autosomal recessive retinitis pigmentosa E150K opsin mutant to the plasma membrane. J Biol Chem. 2010 Sep 17; 285(38):29446-56. Pulagam LP, Palczewski K. PMID: 20628051; PMCID: PMC2937977.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    274. An acyl-covalent enzyme intermediate of lecithin:retinol acyltransferase. J Biol Chem. 2010 Sep 17; 285(38):29217-22. Golczak M, Palczewski K. PMID: 20628054; PMCID: PMC2937952.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    275. Structural characterization of the rod cGMP phosphodiesterase 6. J Mol Biol. 2010 Aug 20; 401(3):363-73. Goc A, Chami M, Lodowski DT, Bosshart P, Moiseenkova-Bell V, Baehr W, Engel A, Palczewski K. PMID: 20600113; PMCID: PMC2917047.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    276. Beta,beta-carotene decreases peroxisome proliferator receptor gamma activity and reduces lipid storage capacity of adipocytes in a beta,beta-carotene oxygenase 1-dependent manner. J Biol Chem. 2010 Sep 03; 285(36):27891-9. Lobo GP, Amengual J, Li HN, Golczak M, Bonet ML, Palczewski K, von Lintig J. PMID: 20573961; PMCID: PMC2934656.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    277. Oligomeric forms of G protein-coupled receptors (GPCRs). Trends Biochem Sci. 2010 Nov; 35(11):595-600. Palczewski K. PMID: 20538466; PMCID: PMC2937196.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    278. Retinoids for treatment of retinal diseases. Trends Pharmacol Sci. 2010 Jun; 31(6):284-95. Palczewski K. PMID: 20435355; PMCID: PMC2882531.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    279. GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base. Bioinformatics. 2010 Jul 15; 26(14):1804-5. Khelashvili G, Dorff K, Shan J, Camacho-Artacho M, Skrabanek L, Vroling B, Bouvier M, Devi LA, George SR, Javitch JA, Lohse MJ, Milligan G, Neubig RR, Palczewski K, Parmentier M, Pin JP, Vriend G, Campagne F, Filizola M. PMID: 20501551; PMCID: PMC2894509.
      View in: PubMed   Mentions: 31     Fields:    
    280. Complexes between photoactivated rhodopsin and transducin: progress and questions. Biochem J. 2010 Apr 28; 428(1):1-10. Jastrzebska B, Tsybovsky Y, Palczewski K. PMID: 20423327; PMCID: PMC2875673.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    281. Palmitoylation stabilizes unliganded rod opsin. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8428-33. Maeda A, Okano K, Park PS, Lem J, Crouch RK, Maeda T, Palczewski K. PMID: 20404157; PMCID: PMC2889565.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    282. Membrane-binding and enzymatic properties of RPE65. Prog Retin Eye Res. 2010 Sep; 29(5):428-42. Kiser PD, Palczewski K. PMID: 20304090; PMCID: PMC2903629.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    283. The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision. Trends Biochem Sci. 2010 Jul; 35(7):400-10. von Lintig J, Kiser PD, Golczak M, Palczewski K. PMID: 20188572; PMCID: PMC2891588.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    284. Alpha-synuclein disrupted dopamine homeostasis leads to dopaminergic neuron degeneration in Caenorhabditis elegans. PLoS One. 2010 Feb 19; 5(2):e9312. Cao P, Yuan Y, Pehek EA, Moise AR, Huang Y, Palczewski K, Feng Z. PMID: 20174477; PMCID: PMC2824852.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    285. Visualizing water molecules in transmembrane proteins using radiolytic labeling methods. Biochemistry. 2010 Feb 09; 49(5):827-34. Orban T, Gupta S, Palczewski K, Chance MR. PMID: 20047303; PMCID: PMC2819031.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    286. Phagocytosis of retinal rod and cone photoreceptors. Physiology (Bethesda). 2010 Feb; 25(1):8-15. Kevany BM, Palczewski K. PMID: 20134024; PMCID: PMC2839896.
      View in: PubMed   Mentions: 240     Fields:    Translation:HumansAnimalsCells
    287. Importance of membrane structural integrity for RPE65 retinoid isomerization activity. J Biol Chem. 2010 Mar 26; 285(13):9667-9682. Golczak M, Kiser PD, Lodowski DT, Maeda A, Palczewski K. PMID: 20100834; PMCID: PMC2843217.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    288. Conformational changes in guanylate cyclase-activating protein 1 induced by Ca2+ and N-terminal fatty acid acylation. Structure. 2010 Jan 13; 18(1):116-26. Orban T, Bereta G, Miyagi M, Wang B, Chance MR, Sousa MC, Palczewski K. PMID: 20152158; PMCID: PMC2822722.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    289. ISX is a retinoic acid-sensitive gatekeeper that controls intestinal beta,beta-carotene absorption and vitamin A production. FASEB J. 2010 Jun; 24(6):1656-66. Lobo GP, Hessel S, Eichinger A, Noy N, Moise AR, Wyss A, Palczewski K, von Lintig J. PMID: 20061533; PMCID: PMC2874479.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    290. Molecular biology and analytical chemistry methods used to probe the retinoid cycle. Methods Mol Biol. 2010; 652:229-45. Golczak M, Bereta G, Maeda A, Palczewski K. PMID: 20552432; PMCID: PMC4607022.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    291. Visualization of retinoid storage and trafficking by two-photon microscopy. Methods Mol Biol. 2010; 652:247-61. Imanishi Y, Palczewski K. PMID: 20552433; PMCID: PMC4607074.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    292. The ATP-binding cassette transporter ABCA4: structural and functional properties and role in retinal disease. Adv Exp Med Biol. 2010; 703:105-25. Tsybovsky Y, Molday RS, Palczewski K. PMID: 20711710; PMCID: PMC2930353.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    293. Multiple pathways ensure retinoid delivery to milk: studies in genetically modified mice. Am J Physiol Endocrinol Metab. 2010 Apr; 298(4):E862-70. O'Byrne SM, Kako Y, Deckelbaum RJ, Hansen IH, Palczewski K, Goldberg IJ, Blaner WS. PMID: 20040693; PMCID: PMC2853214.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    294. Increased adiposity in the retinol saturase-knockout mouse. FASEB J. 2010 Apr; 24(4):1261-70. Moise AR, Lobo GP, Erokwu B, Wilson DL, Peck D, Alvarez S, Domínguez M, Alvarez R, Flask CA, de Lera AR, von Lintig J, Palczewski K. PMID: 19940255; PMCID: PMC2845435.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    295. A functional kinase homology domain is essential for the activity of photoreceptor guanylate cyclase 1. J Biol Chem. 2010 Jan 15; 285(3):1899-908. Bereta G, Wang B, Kiser PD, Baehr W, Jang GF, Palczewski K. PMID: 19901021; PMCID: PMC2804348.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    296. Crystal structure of native RPE65, the retinoid isomerase of the visual cycle. Proc Natl Acad Sci U S A. 2009 Oct 13; 106(41):17325-30. Kiser PD, Golczak M, Lodowski DT, Chance MR, Palczewski K. PMID: 19805034; PMCID: PMC2765077.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    297. Activation of retinoic acid receptors by dihydroretinoids. Mol Pharmacol. 2009 Dec; 76(6):1228-37. Moise AR, Alvarez S, Domínguez M, Alvarez R, Golczak M, Lobo GP, von Lintig J, de Lera AR, Palczewski K. PMID: 19770350; PMCID: PMC2784734.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    298. Use of thallium to identify monovalent cation binding sites in GroEL. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Oct 01; 65(Pt 10):967-71. Kiser PD, Lorimer GH, Palczewski K. PMID: 19851000; PMCID: PMC2765879.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    299. Structural waters define a functional channel mediating activation of the GPCR, rhodopsin. Proc Natl Acad Sci U S A. 2009 Aug 25; 106(34):14367-72. Angel TE, Gupta S, Jastrzebska B, Palczewski K, Chance MR. PMID: 19706523; PMCID: PMC2732891.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    300. WITHDRAWN: Retinol dehydrogenase RDH11 protects the mouse retina from light-induced degeneration. Invest Ophthalmol Vis Sci. 2009 Aug 13. Maeda A, Shiose S, Okano K, Matosky M, Maeda T, Palczewski K. PMID: 19458342.
      View in: PubMed   Mentions: 1     Fields:    
    301. Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina. Invest Ophthalmol Vis Sci. 2009 Nov; 50(11):5435-43. Maeda A, Golczak M, Maeda T, Palczewski K. PMID: 19553623; PMCID: PMC2792889.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsPHPublic Health
    302. Phospholipids are needed for the proper formation, stability, and function of the photoactivated rhodopsin-transducin complex. Biochemistry. 2009 Jun 16; 48(23):5159-70. Jastrzebska B, Goc A, Golczak M, Palczewski K. PMID: 19413332; PMCID: PMC2753473.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    303. Structure of cone photoreceptors. Prog Retin Eye Res. 2009 Jul; 28(4):289-302. Mustafi D, Engel AH, Palczewski K. PMID: 19501669; PMCID: PMC2740621.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimalsCells
    304. Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearance. Invest Ophthalmol Vis Sci. 2009 Oct; 50(10):4917-25. Maeda T, Maeda A, Matosky M, Okano K, Roos S, Tang J, Palczewski K. PMID: 19494204; PMCID: PMC2782428.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsPHPublic Health
    305. Modulation of molecular interactions and function by rhodopsin palmitylation. Biochemistry. 2009 May 26; 48(20):4294-304. Park PS, Sapra KT, Jastrzebska B, Maeda T, Maeda A, Pulawski W, Kono M, Lem J, Crouch RK, Filipek S, Müller DJ, Palczewski K. PMID: 19348429; PMCID: PMC2710298.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    306. Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors. Proc Natl Acad Sci U S A. 2009 May 26; 106(21):8555-60. Angel TE, Chance MR, Palczewski K. PMID: 19433801; PMCID: PMC2688986.
      View in: PubMed   Mentions: 110     Fields:    Translation:AnimalsCells
    307. Clarin-1, encoded by the Usher Syndrome III causative gene, forms a membranous microdomain: possible role of clarin-1 in organizing the actin cytoskeleton. J Biol Chem. 2009 Jul 10; 284(28):18980-93. Tian G, Zhou Y, Hajkova D, Miyagi M, Dinculescu A, Hauswirth WW, Palczewski K, Geng R, Alagramam KN, Isosomppi J, Sankila EM, Flannery JG, Imanishi Y. PMID: 19423712; PMCID: PMC2707243.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    308. Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation. Hum Mol Genet. 2009 Aug 01; 18(15):2748-60. Geng R, Geller SF, Hayashi T, Ray CA, Reh TA, Bermingham-McDonogh O, Jones SM, Wright CG, Melki S, Imanishi Y, Palczewski K, Alagramam KN, Flannery JG. PMID: 19414487; PMCID: PMC2706682.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    309. Evaluation of 9-cis-retinyl acetate therapy in Rpe65-/- mice. Invest Ophthalmol Vis Sci. 2009 Sep; 50(9):4368-78. Maeda T, Maeda A, Casadesus G, Palczewski K, Margaron P. PMID: 19407008; PMCID: PMC2764364.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    310. Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate. Hum Mol Genet. 2009 Jun 15; 18(12):2277-87. Maeda T, Cideciyan AV, Maeda A, Golczak M, Aleman TS, Jacobson SG, Palczewski K. PMID: 19339306; PMCID: PMC2685761.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    311. Involvement of all-trans-retinal in acute light-induced retinopathy of mice. J Biol Chem. 2009 May 29; 284(22):15173-83. Maeda A, Maeda T, Golczak M, Chou S, Desai A, Hoppel CL, Matsuyama S, Palczewski K. PMID: 19304658; PMCID: PMC2685698.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansAnimalsCells
    312. Chemokine receptors and other G protein-coupled receptors. Curr Opin HIV AIDS. 2009 Mar; 4(2):88-95. Lodowski DT, Palczewski K. PMID: 19339946; PMCID: PMC2771364.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    313. Comparative analysis of GPCR crystal structures. Photochem Photobiol. 2009 Mar-Apr; 85(2):425-30. Lodowski DT, Angel TE, Palczewski K. PMID: 19192200; PMCID: PMC2681091.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    314. Focus on molecules: guanylate cyclase-activating proteins (GCAPs). Exp Eye Res. 2009 Jun 15; 89(1):2-3. Baehr W, Palczewski K. PMID: 19162008; PMCID: PMC2739054.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    315. Heterologous expression and purification of the serotonin type 4 receptor from transgenic mouse retina. Biochemistry. 2008 Dec 16; 47(50):13296-307. Salom D, Wu N, Sun W, Dong Z, Palczewski K, Jordan S, Salon JA. PMID: 19053287.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    316. ABCA4 disease progression and a proposed strategy for gene therapy. Hum Mol Genet. 2009 Mar 01; 18(5):931-41. Cideciyan AV, Swider M, Aleman TS, Tsybovsky Y, Schwartz SB, Windsor EA, Roman AJ, Sumaroka A, Steinberg JD, Jacobson SG, Stone EM, Palczewski K. PMID: 19074458; PMCID: PMC2640207.
      View in: PubMed   Mentions: 95     Fields:    Translation:Humans
    317. Different properties of the native and reconstituted heterotrimeric G protein transducin. Biochemistry. 2008 Nov 25; 47(47):12409-19. Goc A, Angel TE, Jastrzebska B, Wang B, Wintrode PL, Palczewski K. PMID: 18975915; PMCID: PMC2645919.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    318. Structural insights into Ca2+-dependent regulation of inositol 1,4,5-trisphosphate receptors by CaBP1. J Biol Chem. 2009 Jan 23; 284(4):2472-81. Li C, Chan J, Haeseleer F, Mikoshiba K, Palczewski K, Ikura M, Ames JB. PMID: 19008222; PMCID: PMC2629100.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    319. Topology of class A G protein-coupled receptors: insights gained from crystal structures of rhodopsins, adrenergic and adenosine receptors. Mol Pharmacol. 2009 Jan; 75(1):1-12. Mustafi D, Palczewski K. PMID: 18945819; PMCID: PMC2652756.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    320. Isolation and functional characterization of a stable complex between photoactivated rhodopsin and the G protein, transducin. FASEB J. 2009 Feb; 23(2):371-81. Jastrzebska B, Golczak M, Fotiadis D, Engel A, Palczewski K. PMID: 18827025; PMCID: PMC2630779.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    321. A novel GCAP1(N104K) mutation in EF-hand 3 (EF3) linked to autosomal dominant cone dystrophy. Vision Res. 2008 Oct; 48(23-24):2425-32. Jiang L, Wheaton D, Bereta G, Zhang K, Palczewski K, Birch DG, Baehr W. PMID: 18706439; PMCID: PMC2584361.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    322. Impact of retinal disease-associated RPE65 mutations on retinoid isomerization. Biochemistry. 2008 Sep 16; 47(37):9856-65. Bereta G, Kiser PD, Golczak M, Sun W, Heon E, Saperstein DA, Palczewski K. PMID: 18722466; PMCID: PMC2610467.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    323. Effects of long-term administration of 9-cis-retinyl acetate on visual function in mice. Invest Ophthalmol Vis Sci. 2009 Jan; 50(1):322-33. Maeda T, Maeda A, Leahy P, Saperstein DA, Palczewski K. PMID: 18708622; PMCID: PMC2615069.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    324. Retinopathy in mice induced by disrupted all-trans-retinal clearance. J Biol Chem. 2008 Sep 26; 283(39):26684-93. Maeda A, Maeda T, Golczak M, Palczewski K. PMID: 18658157; PMCID: PMC2546559.
      View in: PubMed   Mentions: 184     Fields:    Translation:AnimalsCells
    325. Retinyl ester homeostasis in the adipose differentiation-related protein-deficient retina. J Biol Chem. 2008 Sep 05; 283(36):25091-102. Imanishi Y, Sun W, Maeda T, Maeda A, Palczewski K. PMID: 18606814; PMCID: PMC2529016.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    326. Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinal. J Neurosci. 2008 Apr 09; 28(15):4008-14. Zhang H, Fan J, Li S, Karan S, Rohrer B, Palczewski K, Frederick JM, Crouch RK, Baehr W. PMID: 18400900; PMCID: PMC2562706.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    327. The molecular basis of retinoid absorption: a genetic dissection. J Biol Chem. 2008 May 16; 283(20):13510-9. Wongsiriroj N, Piantedosi R, Palczewski K, Goldberg IJ, Johnston TP, Li E, Blaner WS. PMID: 18348983; PMCID: PMC2376245.
      View in: PubMed   Mentions: 68     Fields:    Translation:Animals
    328. Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation. J Biol Chem. 2008 May 16; 283(20):14053-62. Singh P, Wang B, Maeda T, Palczewski K, Tesmer JJ. PMID: 18339619; PMCID: PMC2376226.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    329. Ca2+ -dependent regulation of phototransduction. Photochem Photobiol. 2008 Jul-Aug; 84(4):903-10. Stephen R, Filipek S, Palczewski K, Sousa MC. PMID: 18346093; PMCID: PMC4118144.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    330. Vertebrate membrane proteins: structure, function, and insights from biophysical approaches. Pharmacol Rev. 2008 Mar; 60(1):43-78. Müller DJ, Wu N, Palczewski K. PMID: 18321962; PMCID: PMC2561275.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    331. RBP4 disrupts vitamin A uptake homeostasis in a STRA6-deficient animal model for Matthew-Wood syndrome. Cell Metab. 2008 Mar; 7(3):258-68. Isken A, Golczak M, Oberhauser V, Hunzelmann S, Driever W, Imanishi Y, Palczewski K, von Lintig J. PMID: 18316031; PMCID: PMC2561276.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansAnimalsCells
    332. Mechanical properties of bovine rhodopsin and bacteriorhodopsin: possible roles in folding and function. Langmuir. 2008 Feb 19; 24(4):1330-7. Sapra KT, Park PS, Palczewski K, Muller DJ. PMID: 18266338; PMCID: PMC2504747.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    333. Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. J Biol Chem. 2008 Apr 11; 283(15):9543-54. Golczak M, Maeda A, Bereta G, Maeda T, Kiser PD, Hunzelmann S, von Lintig J, Blaner WS, Palczewski K. PMID: 18195010; PMCID: PMC2441898.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    334. Stereospecificity of retinol saturase: absolute configuration, synthesis, and biological evaluation of dihydroretinoids. J Am Chem Soc. 2008 Jan 30; 130(4):1154-5. Moise AR, Domínguez M, Alvarez S, Alvarez R, Schupp M, Cristancho AG, Kiser PD, de Lera AR, Lazar MA, Palczewski K. PMID: 18179220; PMCID: PMC2621334.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    335. Activation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes. Annu Rev Pharmacol Toxicol. 2008; 48:107-41. Park PS, Lodowski DT, Palczewski K. PMID: 17848137; PMCID: PMC2639654.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    336. Retinyl ester formation by lecithin: retinol acyltransferase is a key regulator of retinoid homeostasis in mouse embryogenesis. J Biol Chem. 2008 Feb 29; 283(9):5611-21. Kim YK, Wassef L, Hamberger L, Piantedosi R, Palczewski K, Blaner WS, Quadro L. PMID: 18093970; PMCID: PMC3771510.
      View in: PubMed   Mentions: 51     Fields:    Translation:Animals
    337. Redundant and unique roles of retinol dehydrogenases in the mouse retina. Proc Natl Acad Sci U S A. 2007 Dec 04; 104(49):19565-70. Maeda A, Maeda T, Sun W, Zhang H, Baehr W, Palczewski K. PMID: 18048336; PMCID: PMC2148329.
      View in: PubMed   Mentions: 68     Fields:    Translation:Animals
    338. Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer. J Biol Chem. 2008 Feb 15; 283(7):4387-94. Whorton MR, Jastrzebska B, Park PS, Fotiadis D, Engel A, Palczewski K, Sunahara RK. PMID: 18033822; PMCID: PMC2651572.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansAnimalsCells
    339. Stabilizing function for myristoyl group revealed by the crystal structure of a neuronal calcium sensor, guanylate cyclase-activating protein 1. Structure. 2007 Nov; 15(11):1392-402. Stephen R, Bereta G, Golczak M, Palczewski K, Sousa MC. PMID: 17997965; PMCID: PMC2556213.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    340. Evidence for RPE65-independent vision in the cone-dominated zebrafish retina. Eur J Neurosci. 2007 Oct; 26(7):1940-9. Schonthaler HB, Lampert JM, Isken A, Rinner O, Mader A, Gesemann M, Oberhauser V, Golczak M, Biehlmaier O, Palczewski K, Neuhauss SC, von Lintig J. PMID: 17868371; PMCID: PMC2435297.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    341. Human cone photoreceptor dependence on RPE65 isomerase. Proc Natl Acad Sci U S A. 2007 Sep 18; 104(38):15123-8. Jacobson SG, Aleman TS, Cideciyan AV, Heon E, Golczak M, Beltran WA, Sumaroka A, Schwartz SB, Roman AJ, Windsor EA, Wilson JM, Aguirre GD, Stone EM, Palczewski K. PMID: 17848510; PMCID: PMC1986623.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimalsCells
    342. Reprint of "Crystal packing analysis of Rhodopsin crystals" [J. Struct. Biol. 158 (2007) 455-462]. J Struct Biol. 2007 Aug; 159(2):253-60. Lodowski DT, Salom D, Le Trong I, Teller DC, Ballesteros JA, Palczewski K, Stenkamp RE. PMID: 17660064.
      View in: PubMed   Mentions: 2     Fields:    
    343. Heterologous expression of the adenosine A1 receptor in transgenic mouse retina. Biochemistry. 2007 Jul 17; 46(28):8350-9. Li N, Salom D, Zhang L, Harris T, Ballesteros JA, Golczak M, Jastrzebska B, Palczewski K, Kurahara C, Juan T, Jordan S, Salon JA. PMID: 17580959.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    344. Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base. BMC Bioinformatics. 2007 May 30; 8:177. Skrabanek L, Murcia M, Bouvier M, Devi L, George SR, Lohse MJ, Milligan G, Neubig R, Palczewski K, Parmentier M, Pin JP, Vriend G, Javitch JA, Campagne F, Filizola M. PMID: 17537266; PMCID: PMC1904246.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    345. Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography. J Cell Biol. 2007 Jun 04; 177(5):917-25. Nickell S, Park PS, Baumeister W, Palczewski K. PMID: 17535966; PMCID: PMC2064290.
      View in: PubMed   Mentions: 132     Fields:    Translation:AnimalsCells
    346. Novel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: biochemical and clinical evaluations. Vision Res. 2007 Jul; 47(15):2055-66. Sun W, Gerth C, Maeda A, Lodowski DT, Van Der Kraak L, Saperstein DA, Héon E, Palczewski K. PMID: 17512964; PMCID: PMC2441904.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    347. Purification, crystallization and structure determination of native GroEL from Escherichia coli lacking bound potassium ions. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jun 01; 63(Pt 6):457-61. Kiser PD, Lodowski DT, Palczewski K. PMID: 17554162; PMCID: PMC2335072.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    348. Delivery of retinoid-based therapies to target tissues. Biochemistry. 2007 Apr 17; 46(15):4449-58. Moise AR, Noy N, Palczewski K, Blaner WS. PMID: 17378589; PMCID: PMC2562735.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    349. International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers. Pharmacol Rev. 2007 Mar; 59(1):5-13. Pin JP, Neubig R, Bouvier M, Devi L, Filizola M, Javitch JA, Lohse MJ, Milligan G, Palczewski K, Parmentier M, Spedding M. PMID: 17329545.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansAnimalsCells
    350. Stabilizing effect of Zn2+ in native bovine rhodopsin. J Biol Chem. 2007 Apr 13; 282(15):11377-85. Park PS, Sapra KT, Kolinski M, Filipek S, Palczewski K, Muller DJ. PMID: 17303564; PMCID: PMC2043472.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    351. Crystal packing analysis of Rhodopsin crystals. J Struct Biol. 2007 Jun; 158(3):455-62. Lodowski DT, Salom D, Le Trong I, Teller DC, Ballesteros JA, Palczewski K, Stenkamp RE. PMID: 17374491; PMCID: PMC1950280.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    352. Visual rhodopsin sees the light: structure and mechanism of G protein signaling. J Biol Chem. 2007 Mar 30; 282(13):9297-9301. Ridge KD, Palczewski K. PMID: 17289671.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    353. Specificity of zebrafish retinol saturase: formation of all-trans-13,14-dihydroretinol and all-trans-7,8- dihydroretinol. Biochemistry. 2007 Feb 20; 46(7):1811-20. Moise AR, Isken A, Domínguez M, de Lera AR, von Lintig J, Palczewski K. PMID: 17253779; PMCID: PMC2561287.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    354. The function of guanylate cyclase 1 and guanylate cyclase 2 in rod and cone photoreceptors. J Biol Chem. 2007 Mar 23; 282(12):8837-47. Baehr W, Karan S, Maeda T, Luo DG, Li S, Bronson JD, Watt CB, Yau KW, Frederick JM, Palczewski K. PMID: 17255100; PMCID: PMC2043484.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    355. Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents. Annu Rev Pharmacol Toxicol. 2007; 47:469-512. Travis GH, Golczak M, Moise AR, Palczewski K. PMID: 16968212; PMCID: PMC2442882.
      View in: PubMed   Mentions: 237     Fields:    Translation:HumansAnimalsCells
    356. Guanylate cyclase-activating proteins and retina disease. Subcell Biochem. 2007; 45:71-91. Baehr W, Palczewski K. PMID: 18193635.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    357. Topology and membrane association of lecithin: retinol acyltransferase. J Biol Chem. 2007 Jan 19; 282(3):2081-90. Moise AR, Golczak M, Imanishi Y, Palczewski K. PMID: 17114808.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    358. Sequestration of retinyl esters is essential for retinoid signaling in the zebrafish embryo. J Biol Chem. 2007 Jan 12; 282(2):1144-51. Isken A, Holzschuh J, Lampert JM, Fischer L, Oberhauser V, Palczewski K, von Lintig J. PMID: 17098734.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    359. The role of the 11-cis-retinal ring methyl substituents in visual pigment formation. Chembiochem. 2006 Nov; 7(11):1815-25. Domínguez M, Alvarez R, Pérez M, Palczewski K, de Lera AR. PMID: 16941510.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    360. Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44):16123-8. Salom D, Lodowski DT, Stenkamp RE, Le Trong I, Golczak M, Jastrzebska B, Harris T, Ballesteros JA, Palczewski K. PMID: 17060607; PMCID: PMC1637547.
      View in: PubMed   Mentions: 215     Fields:    Translation:AnimalsCells
    361. Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice. J Biol Chem. 2006 Dec 08; 281(49):37697-704. Maeda A, Maeda T, Imanishi Y, Sun W, Jastrzebska B, Hatala DA, Winkens HJ, Hofmann KP, Janssen JJ, Baehr W, Driessen CA, Palczewski K. PMID: 17032653; PMCID: PMC4124513.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    362. Improvement in rod and cone function in mouse model of Fundus albipunctatus after pharmacologic treatment with 9-cis-retinal. Invest Ophthalmol Vis Sci. 2006 Oct; 47(10):4540-6. Maeda A, Maeda T, Palczewski K. PMID: 17003450; PMCID: PMC1764978.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    363. Light-driven cone arrestin translocation in cones of postnatal guanylate cyclase-1 knockout mouse retina treated with AAV-GC1. Invest Ophthalmol Vis Sci. 2006 Sep; 47(9):3745-53. Haire SE, Pang J, Boye SL, Sokal I, Craft CM, Palczewski K, Hauswirth WW, Semple-Rowland SL. PMID: 16936082; PMCID: PMC1761699.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    364. Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice. Mol Pharmacol. 2006 Oct; 70(4):1220-9. Maeda A, Maeda T, Golczak M, Imanishi Y, Leahy P, Kubota R, Palczewski K. PMID: 16837623; PMCID: PMC4106413.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    365. Inner retinal photoreception independent of the visual retinoid cycle. Proc Natl Acad Sci U S A. 2006 Jul 05; 103(27):10426-10431. Tu DC, Owens LA, Anderson L, Golczak M, Doyle SE, McCall M, Menaker M, Palczewski K, Van Gelder RN. PMID: 16788071; PMCID: PMC1502474.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    366. Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals. J Struct Biol. 2006 Dec; 156(3):497-504. Salom D, Le Trong I, Pohl E, Ballesteros JA, Stenkamp RE, Palczewski K, Lodowski DT. PMID: 16837211.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    367. Autosomal recessive retinitis pigmentosa and E150K mutation in the opsin gene. J Biol Chem. 2006 Aug 04; 281(31):22289-22298. Zhu L, Imanishi Y, Filipek S, Alekseev A, Jastrzebska B, Sun W, Saperstein DA, Palczewski K. PMID: 16737970; PMCID: PMC1618956.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    368. Lentiviral expression of retinal guanylate cyclase-1 (RetGC1) restores vision in an avian model of childhood blindness. PLoS Med. 2006 Jun; 3(6):e201. Williams ML, Coleman JE, Haire SE, Aleman TS, Cideciyan AV, Sokal I, Palczewski K, Jacobson SG, Semple-Rowland SL. PMID: 16700630; PMCID: PMC1463903.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    369. Aberrant metabolites in mouse models of congenital blinding diseases: formation and storage of retinyl esters. Biochemistry. 2006 Apr 04; 45(13):4210-9. Maeda A, Maeda T, Imanishi Y, Golczak M, Moise AR, Palczewski K. PMID: 16566595; PMCID: PMC1560103.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    370. The crystal structure of GCAP3 suggests molecular mechanism of GCAP-linked cone dystrophies. J Mol Biol. 2006 Jun 02; 359(2):266-75. Stephen R, Palczewski K, Sousa MC. PMID: 16626734; PMCID: PMC4291230.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    371. Structure of the rhodopsin dimer: a working model for G-protein-coupled receptors. Curr Opin Struct Biol. 2006 Apr; 16(2):252-9. Fotiadis D, Jastrzebska B, Philippsen A, Müller DJ, Palczewski K, Engel A. PMID: 16567090.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    372. Functional and structural characterization of rhodopsin oligomers. J Biol Chem. 2006 Apr 28; 281(17):11917-22. Jastrzebska B, Fotiadis D, Jang GF, Stenkamp RE, Engel A, Palczewski K. PMID: 16495215; PMCID: PMC1618955.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    373. Rhodopsin self-associates in asolectin liposomes. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3060-5. Mansoor SE, Palczewski K, Farrens DL. PMID: 16492772; PMCID: PMC1413906.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    374. Detecting molecular interactions that stabilize native bovine rhodopsin. J Mol Biol. 2006 Apr 21; 358(1):255-69. Tanuj Sapra K, Park PS, Filipek S, Engel A, Müller DJ, Palczewski K. PMID: 16519899.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    375. G protein-coupled receptor rhodopsin. Annu Rev Biochem. 2006; 75:743-67. Palczewski K. PMID: 16756510; PMCID: PMC1560097.
      View in: PubMed   Mentions: 344     Fields:    Translation:AnimalsCells
    376. Arrestin interaction with rhodopsin: conceptual models. Cell Biochem Biophys. 2006; 46(1):1-15. Modzelewska A, Filipek S, Palczewski K, Park PS. PMID: 16943619.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    377. Expression of functional G protein-coupled receptors in photoreceptors of transgenic Xenopus laevis. Biochemistry. 2005 Nov 08; 44(44):14509-18. Zhang L, Salom D, He J, Okun A, Ballesteros J, Palczewski K, Li N. PMID: 16262251.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    378. Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis. PLoS Med. 2005 Nov; 2(11):e333. Batten ML, Imanishi Y, Tu DC, Doan T, Zhu L, Pang J, Glushakova L, Moise AR, Baehr W, Van Gelder RN, Hauswirth WW, Rieke F, Palczewski K. PMID: 16250670; PMCID: PMC1274279.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    379. A critical role of CaBP4 in the cone synapse. Invest Ophthalmol Vis Sci. 2005 Nov; 46(11):4320-7. Maeda T, Lem J, Palczewski K, Haeseleer F. PMID: 16249514; PMCID: PMC1351246.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    380. Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness. Mol Ther. 2005 Dec; 12(6):1072-82. Acland GM, Aguirre GD, Bennett J, Aleman TS, Cideciyan AV, Bennicelli J, Dejneka NS, Pearce-Kelling SE, Maguire AM, Palczewski K, Hauswirth WW, Jacobson SG. PMID: 16226919; PMCID: PMC3647373.
      View in: PubMed   Mentions: 199     Fields:    Translation:HumansAnimalsCells
    381. Lecithin:retinol acyltransferase is responsible for amidation of retinylamine, a potent inhibitor of the retinoid cycle. J Biol Chem. 2005 Dec 23; 280(51):42263-73. Golczak M, Imanishi Y, Kuksa V, Maeda T, Kubota R, Palczewski K. PMID: 16216874.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    382. Structural analysis of Mg2+ and Ca2+ binding to CaBP1, a neuron-specific regulator of calcium channels. J Biol Chem. 2005 Nov 11; 280(45):37461-70. Wingard JN, Chan J, Bosanac I, Haeseleer F, Palczewski K, Ikura M, Ames JB. PMID: 16147998; PMCID: PMC1470661.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    383. Imaging G protein-coupled receptor islands. Nat Chem Biol. 2005 Sep; 1(4):184-5. Park PS, Palczewski K. PMID: 16408027.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    384. Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT). J Biol Chem. 2005 Oct 21; 280(42):35647-57. O'Byrne SM, Wongsiriroj N, Libien J, Vogel S, Goldberg IJ, Baehr W, Palczewski K, Blaner WS. PMID: 16115871; PMCID: PMC1352312.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansAnimalsCells
    385. Partial agonism in a G Protein-coupled receptor: role of the retinal ring structure in rhodopsin activation. J Biol Chem. 2005 Oct 07; 280(40):34259-67. Bartl FJ, Fritze O, Ritter E, Herrmann R, Kuksa V, Palczewski K, Hofmann KP, Ernst OP. PMID: 16027155.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    386. Diversifying the repertoire of G protein-coupled receptors through oligomerization. Proc Natl Acad Sci U S A. 2005 Jun 21; 102(25):8793-4. Park PS, Palczewski K. PMID: 15956197; PMCID: PMC1157063.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    387. Rhodopsin: a structural primer for G-protein coupled receptors. Arch Pharm (Weinheim). 2005 Jun; 338(5-6):209-16. Stenkamp RE, Teller DC, Palczewski K. PMID: 15952240.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    388. Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle. Proc Natl Acad Sci U S A. 2005 Jun 07; 102(23):8162-7. Golczak M, Kuksa V, Maeda T, Moise AR, Palczewski K. PMID: 15917330; PMCID: PMC1149451.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    389. Metabolism and transactivation activity of 13,14-dihydroretinoic acid. J Biol Chem. 2005 Jul 29; 280(30):27815-25. Moise AR, Kuksa V, Blaner WS, Baehr W, Palczewski K. PMID: 15911617; PMCID: PMC1352314.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    390. Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success. Proc Natl Acad Sci U S A. 2005 Apr 26; 102(17):6177-82. Jacobson SG, Aleman TS, Cideciyan AV, Sumaroka A, Schwartz SB, Windsor EA, Traboulsi EI, Heon E, Pittler SJ, Milam AH, Maguire AM, Palczewski K, Stone EM, Bennett J. PMID: 15837919; PMCID: PMC1087926.
      View in: PubMed   Mentions: 142     Fields:    Translation:HumansAnimalsCells
    391. A novel GCAP1 missense mutation (L151F) in a large family with autosomal dominant cone-rod dystrophy (adCORD). Invest Ophthalmol Vis Sci. 2005 Apr; 46(4):1124-32. Sokal I, Dupps WJ, Grassi MA, Brown J, Affatigato LM, Roychowdhury N, Yang L, Filipek S, Palczewski K, Stone EM, Baehr W. PMID: 15790869; PMCID: PMC1352313.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    392. Related enzymes solve evolutionarily recurrent problems in the metabolism of carotenoids. Trends Plant Sci. 2005 Apr; 10(4):178-86. Moise AR, von Lintig J, Palczewski K. PMID: 15817419.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    393. Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo. J Biol Chem. 2005 May 13; 280(19):18822-32. Maeda A, Maeda T, Imanishi Y, Kuksa V, Alekseev A, Bronson JD, Zhang H, Zhu L, Sun W, Saperstein DA, Rieke F, Baehr W, Palczewski K. PMID: 15755727; PMCID: PMC1283069.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansAnimalsCells
    394. Microsomal glutathione S-transferase 1 in the retinal pigment epithelium: protection against oxidative stress and a potential role in aging. Biochemistry. 2005 Jan 18; 44(2):480-9. Maeda A, Crabb JW, Palczewski K. PMID: 15641772; PMCID: PMC1351247.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    395. Delayed dark adaptation in 11-cis-retinol dehydrogenase-deficient mice: a role of RDH11 in visual processes in vivo. J Biol Chem. 2005 Mar 11; 280(10):8694-704. Kim TS, Maeda A, Maeda T, Heinlein C, Kedishvili N, Palczewski K, Nelson PS. PMID: 15634683; PMCID: PMC1351245.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    396. Oligomerization of G protein-coupled receptors: past, present, and future. Biochemistry. 2004 Dec 21; 43(50):15643-56. Park PS, Filipek S, Wells JW, Palczewski K. PMID: 15595821; PMCID: PMC1752221.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    397. A novel mutation (I143NT) in guanylate cyclase-activating protein 1 (GCAP1) associated with autosomal dominant cone degeneration. Invest Ophthalmol Vis Sci. 2004 Nov; 45(11):3863-70. Nishiguchi KM, Sokal I, Yang L, Roychowdhury N, Palczewski K, Berson EL, Dryja TP, Baehr W. PMID: 15505030; PMCID: PMC1475955.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    398. The supramolecular structure of the GPCR rhodopsin in solution and native disc membranes. Mol Membr Biol. 2004 Nov-Dec; 21(6):435-46. Suda K, Filipek S, Palczewski K, Engel A, Fotiadis D. PMID: 15764373; PMCID: PMC1351286.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    399. Functional characterization of rhodopsin monomers and dimers in detergents. J Biol Chem. 2004 Dec 24; 279(52):54663-75. Jastrzebska B, Maeda T, Zhu L, Fotiadis D, Filipek S, Engel A, Stenkamp RE, Palczewski K. PMID: 15489507; PMCID: PMC1351296.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    400. Hippocalcin in the olfactory epithelium: a mediator of second messenger signaling. Biochem Biophys Res Commun. 2004 Oct 01; 322(4):1131-9. Mammen A, Simpson PJ, Mamman A, Simpson JP, Nighorn A, Imanishi Y, Palczewski K, Ronnett GV, Moon C. PMID: 15336960.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    401. Nonvisual photoreception in the chick iris. Science. 2004 Oct 01; 306(5693):129-31. Tu DC, Batten ML, Palczewski K, Van Gelder RN. PMID: 15459395.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    402. Guanylate cyclase-activating proteins: structure, function, and diversity. Biochem Biophys Res Commun. 2004 Oct 01; 322(4):1123-30. Palczewski K, Sokal I, Baehr W. PMID: 15336959.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    403. A naturally occurring mutation of the opsin gene (T4R) in dogs affects glycosylation and stability of the G protein-coupled receptor. J Biol Chem. 2004 Dec 17; 279(51):53828-39. Zhu L, Jang GF, Jastrzebska B, Filipek S, Pearce-Kelling SE, Aguirre GD, Stenkamp RE, Acland GM, Palczewski K. PMID: 15459196; PMCID: PMC1351288.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    404. Essential role of Ca2+-binding protein 4, a Cav1.4 channel regulator, in photoreceptor synaptic function. Nat Neurosci. 2004 Oct; 7(10):1079-87. Haeseleer F, Imanishi Y, Maeda T, Possin DE, Maeda A, Lee A, Rieke F, Palczewski K. PMID: 15452577; PMCID: PMC1352161.
      View in: PubMed   Mentions: 184     Fields:    Translation:HumansAnimalsCells
    405. Identification of all-trans-retinol:all-trans-13,14-dihydroretinol saturase. J Biol Chem. 2004 Nov 26; 279(48):50230-42. Moise AR, Kuksa V, Imanishi Y, Palczewski K. PMID: 15358783; PMCID: PMC2665716.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    406. Ca2+ binding to EF hands 1 and 3 is essential for the interaction of apoptosis-linked gene-2 with Alix/AIP1 in ocular melanoma. Biochemistry. 2004 Sep 07; 43(35):11175-86. Subramanian L, Crabb JW, Cox J, Durussel I, Walker TM, van Ginkel PR, Bhattacharya S, Dellaria JM, Palczewski K, Polans AS. PMID: 15366927; PMCID: PMC1351334.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    407. Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice. J Biol Chem. 2004 Nov 12; 279(46):48189-96. Liang Y, Fotiadis D, Maeda T, Maeda A, Modzelewska A, Filipek S, Saperstein DA, Engel A, Palczewski K. PMID: 15337746; PMCID: PMC1351248.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    408. Retinosomes: new insights into intracellular managing of hydrophobic substances in lipid bodies. J Cell Biol. 2004 Aug 16; 166(4):447-53. Imanishi Y, Gerke V, Palczewski K. PMID: 15314061; PMCID: PMC1360213.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    409. Diversity of guanylate cyclase-activating proteins (GCAPs) in teleost fish: characterization of three novel GCAPs (GCAP4, GCAP5, GCAP7) from zebrafish (Danio rerio) and prediction of eight GCAPs (GCAP1-8) in pufferfish (Fugu rubripes). J Mol Evol. 2004 Aug; 59(2):204-217. Imanishi Y, Yang L, Sokal I, Filipek S, Palczewski K, Baehr W. PMID: 15486694; PMCID: PMC1351297.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    410. The G protein-coupled receptor rhodopsin in the native membrane. FEBS Lett. 2004 Apr 30; 564(3):281-288. Fotiadis D, Liang Y, Filipek S, Saperstein DA, Engel A, Palczewski K. PMID: 15111110; PMCID: PMC1393389.
      View in: PubMed   Mentions: 101     Fields:    Translation:AnimalsCells
    411. Impairment of the transient pupillary light reflex in Rpe65(-/-) mice and humans with leber congenital amaurosis. Invest Ophthalmol Vis Sci. 2004 Apr; 45(4):1259-71. Aleman TS, Jacobson SG, Chico JD, Scott ML, Cheung AY, Windsor EA, Furushima M, Redmond TM, Bennett J, Palczewski K, Cideciyan AV. PMID: 15037595.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimals
    412. A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface. Photochem Photobiol Sci. 2004 Jun; 3(6):628-38. Filipek S, Krzysko KA, Fotiadis D, Liang Y, Saperstein DA, Engel A, Palczewski K. PMID: 15170495.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    413. Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye. J Cell Biol. 2004 Feb 02; 164(3):373-83. Imanishi Y, Batten ML, Piston DW, Baehr W, Palczewski K. PMID: 14745001; PMCID: PMC1360214.
      View in: PubMed   Mentions: 109     Fields:    Translation:AnimalsCells
    414. Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver. J Biol Chem. 2004 Mar 12; 279(11):10422-32. Batten ML, Imanishi Y, Maeda T, Tu DC, Moise AR, Bronson D, Possin D, Van Gelder RN, Baehr W, Palczewski K. PMID: 14684738; PMCID: PMC1351249.
      View in: PubMed   Mentions: 211     Fields:    Translation:Animals
    415. Retinoid cycle in the vertebrate retina: experimental approaches and mechanisms of isomerization. Vision Res. 2003 Dec; 43(28):2959-81. Kuksa V, Imanishi Y, Batten M, Palczewski K, Moise AR. PMID: 14611933.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    416. Novel targeting strategy for generating mouse models with defects in the retinoid cycle. Vision Res. 2003 Dec; 43(28):3075-9. Driessen C, Winkens H, Haeseleer F, Palczewski K, Janssen J. PMID: 14611944.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    417. The retinoid cycle and retina disease. Vision Res. 2003 Dec; 43(28):2957-8. Baehr W, Wu SM, Bird AC, Palczewski K. PMID: 14611932.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    418. Evolutionary analysis of rhodopsin and cone pigments: connecting the three-dimensional structure with spectral tuning and signal transfer. FEBS Lett. 2003 Nov 27; 555(1):151-9. Teller DC, Stenkamp RE, Palczewski K. PMID: 14630336; PMCID: PMC1468034.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    419. Phototransduction: crystal clear. Trends Biochem Sci. 2003 Sep; 28(9):479-87. Ridge KD, Abdulaev NG, Sousa M, Palczewski K. PMID: 13678959.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    420. Albipunctate retinopathy with cone dysfunction and no abnormality in the RDH5 or RLBP1 genes. Retina. 2003 Aug; 23(4):543-6. Marmor MF, Haeseleer F, Palczewski K. PMID: 12972770.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    421. Rhodopsin phosphorylation: 30 years later. Prog Retin Eye Res. 2003 Jul; 22(4):417-34. Maeda T, Imanishi Y, Palczewski K. PMID: 12742390.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    422. Evaluation of the role of the retinal G protein-coupled receptor (RGR) in the vertebrate retina in vivo. J Neurochem. 2003 May; 85(4):944-56. Maeda T, Van Hooser JP, Driessen CA, Filipek S, Janssen JJ, Palczewski K. PMID: 12716426; PMCID: PMC1435694.
      View in: PubMed   Mentions: 46     Fields:    Translation:Animals
    423. Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin. J Biol Chem. 2003 Jul 04; 278(27):24896-24903. Schädel SA, Heck M, Maretzki D, Filipek S, Teller DC, Palczewski K, Hofmann KP. PMID: 12707280; PMCID: PMC1360283.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    424. Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes. J Biol Chem. 2003 Jun 13; 278(24):21655-21662. Liang Y, Fotiadis D, Filipek S, Saperstein DA, Palczewski K, Engel A. PMID: 12663652; PMCID: PMC1360145.
      View in: PubMed   Mentions: 227     Fields:    Translation:AnimalsCells
    425. Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin. Biochemistry. 2003 Mar 18; 42(10):2759-67. Mirzadegan T, Benkö G, Filipek S, Palczewski K. PMID: 12627940; PMCID: PMC1435692.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimals
    426. Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2290-5. Fritze O, Filipek S, Kuksa V, Palczewski K, Hofmann KP, Ernst OP. PMID: 12601165; PMCID: PMC151333.
      View in: PubMed   Mentions: 131     Fields:    Translation:HumansAnimalsCells
    427. The crystallographic model of rhodopsin and its use in studies of other G protein-coupled receptors. Annu Rev Biophys Biomol Struct. 2003; 32:375-97. Filipek S, Teller DC, Palczewski K, Stenkamp R. PMID: 12574068; PMCID: PMC1351250.
      View in: PubMed   Mentions: 41     Fields:    Translation:Cells
    428. Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosa. J Biol Chem. 2003 Apr 18; 278(16):14442-14450. Noorwez SM, Kuksa V, Imanishi Y, Zhu L, Filipek S, Palczewski K, Kaushal S. PMID: 12566452; PMCID: PMC1361689.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    429. Atomic-force microscopy: Rhodopsin dimers in native disc membranes. Nature. 2003 Jan 09; 421(6919):127-8. Fotiadis D, Liang Y, Filipek S, Saperstein DA, Engel A, Palczewski K. PMID: 12520290.
      View in: PubMed   Mentions: 263     Fields:    Translation:AnimalsCells
    430. Photoreceptor guanylate cyclase variants: cGMP production under control. Acta Biochim Pol. 2003; 50(4):1075-95. Sokal I, Alekseev A, Palczewski K. PMID: 14739996; PMCID: PMC1351243.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    431. Identification of protein kinase C isozymes responsible for the phosphorylation of photoreceptor-specific RGS9-1 at Ser475. J Biol Chem. 2003 Mar 07; 278(10):8316-25. Sokal I, Hu G, Liang Y, Mao M, Wensel TG, Palczewski K. PMID: 12499365.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    432. Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina. J Biol Chem. 2002 Nov 22; 277(47):45537-45546. Haeseleer F, Jang GF, Imanishi Y, Driessen CAGG, Matsumura M, Nelson PS, Palczewski K. PMID: 12226107; PMCID: PMC1435693.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    433. Biochemical and physiological properties of rhodopsin regenerated with 11-cis-6-ring- and 7-ring-retinals. J Biol Chem. 2002 Nov 01; 277(44):42315-42324. Kuksa V, Bartl F, Maeda T, Jang GF, Ritter E, Heck M, Preston Van Hooser J, Liang Y, Filipek S, Gelb MH, Hofmann KP, Palczewski K. PMID: 12176994; PMCID: PMC1363677.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    434. Vaccination with recoverin, a cancer-associated retinopathy antigen, induces autoimmune retinal dysfunction and tumor cell regression in mice. Eur J Immunol. 2002 Aug; 32(8):2300-7. Maeda A, Maeda T, Ohguro H, Palczewski K, Sato N. PMID: 12209643.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCellsPHPublic Health
    435. Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca(2+) release channels. Proc Natl Acad Sci U S A. 2002 May 28; 99(11):7711-6. Yang J, McBride S, Mak DO, Vardi N, Palczewski K, Haeseleer F, Foskett JK. PMID: 12032348; PMCID: PMC124329.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    436. G protein-coupled receptor rhodopsin: a prospectus. Annu Rev Physiol. 2003; 65:851-79. Filipek S, Stenkamp RE, Teller DC, Palczewski K. PMID: 12471166; PMCID: PMC1435697.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    437. GCAP1 rescues rod photoreceptor response in GCAP1/GCAP2 knockout mice. EMBO J. 2002 Apr 02; 21(7):1545-54. Howes KA, Pennesi ME, Sokal I, Church-Kopish J, Schmidt B, Margolis D, Frederick JM, Rieke F, Palczewski K, Wu SM, Detwiler PB, Baehr W. PMID: 11927539; PMCID: PMC125366.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    438. Recovery of visual functions in a mouse model of Leber congenital amaurosis. J Biol Chem. 2002 May 24; 277(21):19173-82. Van Hooser JP, Liang Y, Maeda T, Kuksa V, Jang GF, He YG, Rieke F, Fong HK, Detwiler PB, Palczewski K. PMID: 11897783; PMCID: PMC1470660.
      View in: PubMed   Mentions: 83     Fields:    Translation:Animals
    439. Differential modulation of Ca(v)2.1 channels by calmodulin and Ca2+-binding protein 1. Nat Neurosci. 2002 Mar; 5(3):210-7. Lee A, Westenbroek RE, Haeseleer F, Palczewski K, Scheuer T, Catterall WA. PMID: 11865310; PMCID: PMC1435861.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimalsCells
    440. Calcium-binding proteins: intracellular sensors from the calmodulin superfamily. Biochem Biophys Res Commun. 2002 Jan 18; 290(2):615-23. Haeseleer F, Imanishi Y, Sokal I, Filipek S, Palczewski K. PMID: 11785943.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    441. Soluble fusion proteins between single transmembrane photoreceptor guanylyl cyclases and their activators. Biochemistry. 2002 Jan 08; 41(1):251-7. Sokal I, Alekseev A, Baehr W, Haeseleer F, Palczewski K. PMID: 11772023; PMCID: PMC1363675.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    442. Crystal Structure of Rhodopsin: Implication for Vision and Beyond. Mechanisms of Acti. ScientificWorldJournal. 2002; 2:106-107. Palczewski K. PMID: 29973825; PMCID: PMC6009445.
      View in: PubMed   Mentions:    Fields:    
    443. Rhodopsin and its kinase. Methods Enzymol. 2002; 343:578-600. Sokal I, Pulvermüller A, Buczylko J, Hofmann KP, Palczewski K. PMID: 11665593; PMCID: PMC1363672.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    444. Calmodulin and Ca2+-binding proteins (CaBPs): variations on a theme. Adv Exp Med Biol. 2002; 514:303-17. Haeseleer F, Palczewski K. PMID: 12596929.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    445. Characterization of retinal guanylate cyclase-activating protein 3 (GCAP3) from zebrafish to man. Eur J Neurosci. 2002 Jan; 15(1):63-78. Imanishi Y, Li N, Sokal I, Sowa ME, Lichtarge O, Wensel TG, Saperstein DA, Baehr W, Palczewski K. PMID: 11860507; PMCID: PMC1363676.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    446. Gene transfer mediated by recombinant baculovirus into mouse eye. Invest Ophthalmol Vis Sci. 2001 Dec; 42(13):3294-300. Haeseleer F, Imanishi Y, Saperstein DA, Palczewski K. PMID: 11726636; PMCID: PMC1436034.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    447. Isomerization of 11-cis-retinoids to all-trans-retinoids in vitro and in vivo. J Biol Chem. 2001 Dec 21; 276(51):48483-93. McBee JK, Van Hooser JP, Jang GF, Palczewski K. PMID: 11604395; PMCID: PMC1409735.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    448. G protein-coupled receptor drug discovery: implications from the crystal structure of rhodopsin. Curr Opin Drug Discov Devel. 2001 Sep; 4(5):561-74. Ballesteros J, Palczewski K. PMID: 12825452; PMCID: PMC1383658.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    449. Calcium-sensitive regions of GCAP1 as observed by chemical modifications, fluorescence, and EPR spectroscopies. J Biol Chem. 2001 Nov 16; 276(46):43361-73. Sokal I, Li N, Klug CS, Filipek S, Hubbell WL, Baehr W, Palczewski K. PMID: 11524415; PMCID: PMC1363678.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    450. Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptors. Proc Natl Acad Sci U S A. 2001 Aug 14; 98(17):9948-53. Mendez A, Burns ME, Sokal I, Dizhoor AM, Baehr W, Palczewski K, Baylor DA, Chen J. PMID: 11493703; PMCID: PMC55558.
      View in: PubMed   Mentions: 154     Fields:    Translation:AnimalsCells
    451. Advances in determination of a high-resolution three-dimensional structure of rhodopsin, a model of G-protein-coupled receptors (GPCRs). Biochemistry. 2001 Jul 03; 40(26):7761-72. Teller DC, Okada T, Behnke CA, Palczewski K, Stenkamp RE. PMID: 11425302; PMCID: PMC1698954.
      View in: PubMed   Mentions: 171     Fields:    Translation:HumansAnimalsCells
    452. Characterization of a dehydrogenase activity responsible for oxidation of 11-cis-retinol in the retinal pigment epithelium of mice with a disrupted RDH5 gene. A model for the human hereditary disease fundus albipunctatus. J Biol Chem. 2001 Aug 31; 276(35):32456-65. Jang GF, Van Hooser JP, Kuksa V, McBee JK, He YG, Janssen JJ, Driessen CA, Palczewski K. PMID: 11418621; PMCID: PMC1361690.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    453. Activation of rhodopsin: new insights from structural and biochemical studies. Trends Biochem Sci. 2001 May; 26(5):318-24. Okada T, Ernst OP, Palczewski K, Hofmann KP. PMID: 11343925.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimalsCells
    454. Mechanism of rhodopsin activation as examined with ring-constrained retinal analogs and the crystal structure of the ground state protein. J Biol Chem. 2001 Jul 13; 276(28):26148-53. Jang GF, Kuksa V, Filipek S, Bartl F, Ritter E, Gelb MH, Hofmann KP, Palczewski K. PMID: 11316815; PMCID: PMC1361691.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    455. Phosphorylation of RGS9-1 by an endogenous protein kinase in rod outer segments. J Biol Chem. 2001 Jun 22; 276(25):22287-95. Hu G, Jang GF, Cowan CW, Wensel TG, Palczewski K. PMID: 11292825; PMCID: PMC1364467.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    456. Pan1b (17betaHSD11)-enzymatic activity and distribution in the lung. Mol Cell Endocrinol. 2001 Jan 22; 171(1-2):111-7. Brereton P, Suzuki T, Sasano H, Li K, Duarte C, Obeyesekere V, Haeseleer F, Palczewski K, Smith I, Komesaroff P, Krozowski Z. PMID: 11165019.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    457. Ca(2+)-binding proteins in the retina: from discovery to etiology of human disease(1). Biochim Biophys Acta. 2000 Dec 20; 1498(2-3):233-51. Sokal I, Li N, Verlinde CL, Haeseleer F, Baehr W, Palczewski K. PMID: 11108966.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    458. Light-induced conformational changes of rhodopsin probed by fluorescent alexa594 immobilized on the cytoplasmic surface. Biochemistry. 2000 Dec 12; 39(49):15225-33. Imamoto Y, Kataoka M, Tokunaga F, Palczewski K. PMID: 11106502; PMCID: PMC1382172.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    459. Isomerization of all-trans-retinol to cis-retinols in bovine retinal pigment epithelial cells: dependence on the specificity of retinoid-binding proteins. Biochemistry. 2000 Sep 19; 39(37):11370-80. McBee JK, Kuksa V, Alvarez R, de Lera AR, Prezhdo O, Haeseleer F, Sokal I, Palczewski K. PMID: 10985782; PMCID: PMC1408314.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    460. Stereoisomeric specificity of the retinoid cycle in the vertebrate retina. J Biol Chem. 2000 Sep 08; 275(36):28128-38. Jang GF, McBee JK, Alekseev AM, Haeseleer F, Palczewski K. PMID: 10871622; PMCID: PMC1435698.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    461. Rod and cone visual cycle consequences of a null mutation in the 11-cis-retinol dehydrogenase gene in man. Vis Neurosci. 2000 Sep-Oct; 17(5):667-678. Cideciyan AV, Haeseleer F, Fariss RN, Aleman TS, Jang GF, Verlinde CLMJ, Marmor MF, Jacobson SG, Palczewski K. PMID: 11153648; PMCID: PMC1410813.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    462. Crystal structure of rhodopsin: A G protein-coupled receptor. Science. 2000 Aug 04; 289(5480):739-45. Palczewski K, Kumasaka T, Hori T, Behnke CA, Motoshima H, Fox BA, Le Trong I, Teller DC, Okada T, Stenkamp RE, Yamamoto M, Miyano M. PMID: 10926528.
      View in: PubMed   Mentions: 1636     Fields:    Translation:AnimalsCells
    463. Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness. Proc Natl Acad Sci U S A. 2000 Jul 18; 97(15):8623-8. Van Hooser JP, Aleman TS, He YG, Cideciyan AV, Kuksa V, Pittler SJ, Stone EM, Jacobson SG, Palczewski K. PMID: 10869443; PMCID: PMC26998.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansAnimalsCells
    464. Disruption of the 11-cis-retinol dehydrogenase gene leads to accumulation of cis-retinols and cis-retinyl esters. Mol Cell Biol. 2000 Jun; 20(12):4275-87. Driessen CA, Winkens HJ, Hoffmann K, Kuhlmann LD, Janssen BP, Van Vugt AH, Van Hooser JP, Wieringa BE, Deutman AF, Palczewski K, Ruether K, Janssen JJ. PMID: 10825191; PMCID: PMC85795.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    465. The ADP ribosylation factor nucleotide exchange factor ARNO promotes beta-arrestin release necessary for luteinizing hormone/choriogonadotropin receptor desensitization. Proc Natl Acad Sci U S A. 2000 May 23; 97(11):5901-6. Mukherjee S, Gurevich VV, Jones JC, Casanova JE, Frank SR, Maizels ET, Bader MF, Kahn RA, Palczewski K, Aktories K, Hunzicker-Dunn M. PMID: 10811902; PMCID: PMC18531.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    466. X-Ray diffraction analysis of three-dimensional crystals of bovine rhodopsin obtained from mixed micelles. J Struct Biol. 2000 May; 130(1):73-80. Okada T, Le Trong I, Fox BA, Behnke CA, Stenkamp RE, Palczewski K. PMID: 10806093.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    467. Ca(2+)-binding proteins in the retina: structure, function, and the etiology of human visual diseases. Bioessays. 2000 Apr; 22(4):337-50. Palczewski K, Polans AS, Baehr W, Ames JB. PMID: 10723031.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    468. Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin. J Biol Chem. 2000 Jan 14; 275(2):1247-60. Haeseleer F, Sokal I, Verlinde CL, Erdjument-Bromage H, Tempst P, Pronin AN, Benovic JL, Fariss RN, Palczewski K. PMID: 10625670; PMCID: PMC1364469.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    469. Multienzyme analysis of visual cycle. Methods Enzymol. 2000; 316:330-44. Stecher H, Palczewski K. PMID: 10800685; PMCID: PMC1560099.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    470. Phase partition and high-performance liquid chromatography assays of retinoid dehydrogenases. Methods Enzymol. 2000; 316:359-71. Saari JC, Garwin GG, Haeseleer F, Jang GF, Palczewski K. PMID: 10800687; PMCID: PMC1552099.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    471. Short-chain dehydrogenases/reductases in retina. Methods Enzymol. 2000; 316:372-83. Haeseleer F, Palczewski K. PMID: 10800688.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    472. Structural analysis of protein prenyl groups and associated C-terminal modifications. Methods Enzymol. 2000; 316:436-51. Whitten ME, Yokoyama K, Schieltz D, Ghomashchi F, Lam D, Yates JR, Palczewski K, Gelb MH. PMID: 10800693; PMCID: PMC1435690.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    473. Structure, alternative splicing, and expression of the human RGS9 gene. Gene. 1999 Nov 15; 240(1):23-34. Zhang K, Howes KA, He W, Bronson JD, Pettenati MJ, Chen C, Palczewski K, Wensel TG, Baehr W. PMID: 10564809.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    474. Isomerization of all-trans-9- and 13-desmethylretinol by retinal pigment epithelial cells. Biochemistry. 1999 Oct 12; 38(41):13542-50. Stecher H, Prezhdo O, Das J, Crouch RK, Palczewski K. PMID: 10521261.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    475. Kinetics of visual pigment regeneration in excised mouse eyes and in mice with a targeted disruption of the gene encoding interphotoreceptor retinoid-binding protein or arrestin. Biochemistry. 1999 Sep 14; 38(37):12012-9. Palczewski K, Van Hooser JP, Garwin GG, Chen J, Liou GI, Saari JC. PMID: 10508404.
      View in: PubMed   Mentions: 70     Fields:    Translation:Animals
    476. Conformational changes in guanylyl cyclase-activating protein 1 (GCAP1) and its tryptophan mutants as a function of calcium concentration. J Biol Chem. 1999 Jul 09; 274(28):19829-37. Sokal I, Otto-Bruc AE, Surgucheva I, Verlinde CL, Wang CK, Baehr W, Palczewski K. PMID: 10391927.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    477. A novel form of rhodopsin kinase from chicken retina and pineal gland. FEBS Lett. 1999 Jul 02; 454(1-2):115-21. Zhao X, Yokoyama K, Whitten ME, Huang J, Gelb MH, Palczewski K. PMID: 10413107.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    478. Three-dimensional structure of guanylyl cyclase activating protein-2, a calcium-sensitive modulator of photoreceptor guanylyl cyclases. J Biol Chem. 1999 Jul 02; 274(27):19329-37. Ames JB, Dizhoor AM, Ikura M, Palczewski K, Stryer L. PMID: 10383444.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    479. beta-arrestin-dependent desensitization of luteinizing hormone/choriogonadotropin receptor is prevented by a synthetic peptide corresponding to the third intracellular loop of the receptor. J Biol Chem. 1999 May 07; 274(19):12984-9. Mukherjee S, Palczewski K, Gurevich VV, Hunzicker-Dunn M. PMID: 10224047.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    480. Preferential release of 11-cis-retinol from retinal pigment epithelial cells in the presence of cellular retinaldehyde-binding protein. J Biol Chem. 1999 Mar 26; 274(13):8577-85. Stecher H, Gelb MH, Saari JC, Palczewski K. PMID: 10085092.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    481. Molecular characterization of a third member of the guanylyl cyclase-activating protein subfamily. J Biol Chem. 1999 Mar 05; 274(10):6526-35. Haeseleer F, Sokal I, Li N, Pettenati M, Rao N, Bronson D, Wechter R, Baehr W, Palczewski K. PMID: 10037746.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    482. Light inhibition of bovine retinal rod guanylyl cyclase mediated by beta gamma-transducin. Biochemistry. 1999 Mar 02; 38(9):2611-6. Wolbring G, Baehr W, Palczewski K, Schnetkamp PP. PMID: 10052930.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    483. Identification of a guanylyl cyclase-activating protein-binding site within the catalytic domain of retinal guanylyl cyclase 1. Biochemistry. 1999 Feb 02; 38(5):1387-93. Sokal I, Haeseleer F, Arendt A, Adman ET, Hargrave PA, Palczewski K. PMID: 9931003.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    484. A direct role for arrestins in desensitization of the luteinizing hormone/choriogonadotropin receptor in porcine ovarian follicular membranes. Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2):493-8. Mukherjee S, Palczewski K, Gurevich V, Benovic JL, Banga JP, Hunzicker-Dunn M. PMID: 9892661; PMCID: PMC15164.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    485. Molecular mechanism of visual transduction. Novartis Found Symp. 1999; 224:191-204; discussion 204-7. Palczewski K, Verlinde CL, Haeseleer F. PMID: 10614052.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    486. Phosphorylation of photolyzed rhodopsin is calcium-insensitive in retina permeabilized by alpha-toxin. Proc Natl Acad Sci U S A. 1998 Dec 08; 95(25):15014-9. Otto-Bruc AE, Fariss RN, Van Hooser JP, Palczewski K. PMID: 9844007; PMCID: PMC24567.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    487. Identification of a single phosphorylation site within octopus rhodopsin. Photochem Photobiol. 1998 Dec; 68(6):824-8. Ohguro H, Yoshida N, Shindou H, Crabb JW, Palczewski K, Tsuda M. PMID: 9867032.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    488. Molecular characterization of a novel short-chain dehydrogenase/reductase that reduces all-trans-retinal. J Biol Chem. 1998 Aug 21; 273(34):21790-9. Haeseleer F, Huang J, Lebioda L, Saari JC, Palczewski K. PMID: 9705317.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    489. GCAP1 (Y99C) mutant is constitutively active in autosomal dominant cone dystrophy. Mol Cell. 1998 Jul; 2(1):129-33. Sokal I, Li N, Surgucheva I, Warren MJ, Payne AM, Bhattacharya SS, Baehr W, Palczewski K. PMID: 9702199.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    490. Calcium-sensitive particulate guanylyl cyclase as a modulator of cAMP in olfactory receptor neurons. J Neurosci. 1998 May 01; 18(9):3195-205. Moon C, Jaberi P, Otto-Bruc A, Baehr W, Palczewski K, Ronnett GV. PMID: 9547228; PMCID: PMC6792646.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    491. Reduction of all-trans-retinal limits regeneration of visual pigment in mice. Vision Res. 1998 May; 38(10):1325-33. Saari JC, Garwin GG, Van Hooser JP, Palczewski K. PMID: 9667000.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    492. High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rods. Proc Natl Acad Sci U S A. 1998 Apr 28; 95(9):5351-6. Cowan CW, Fariss RN, Sokal I, Palczewski K, Wensel TG. PMID: 9560279; PMCID: PMC20264.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    493. Guanylate-cyclase-inhibitory protein is a frog retinal Ca2+-binding protein related to mammalian guanylate-cyclase-activating proteins. Eur J Biochem. 1998 Mar 15; 252(3):591-9. Li N, Fariss RN, Zhang K, Otto-Bruc A, Haeseleer F, Bronson D, Qin N, Yamazaki A, Subbaraya I, Milam AH, Palczewski K, Baehr W. PMID: 9546678.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    494. Molecular forms of human rhodopsin kinase (GRK1). J Biol Chem. 1998 Feb 27; 273(9):5124-31. Zhao X, Huang J, Khani SC, Palczewski K. PMID: 9478965.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    495. A null mutation in the photoreceptor guanylate cyclase gene causes the retinal degeneration chicken phenotype. Proc Natl Acad Sci U S A. 1998 Feb 03; 95(3):1271-6. Semple-Rowland SL, Lee NR, Van Hooser JP, Palczewski K, Baehr W. PMID: 9448321; PMCID: PMC18742.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    496. Changes in biological activity and folding of guanylate cyclase-activating protein 1 as a function of calcium. Biochemistry. 1998 Jan 06; 37(1):248-57. Rudnicka-Nawrot M, Surgucheva I, Hulmes JD, Haeseleer F, Sokal I, Crabb JW, Baehr W, Palczewski K. PMID: 9425045.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    497. Null mutation in the rhodopsin kinase gene slows recovery kinetics of rod and cone phototransduction in man. Proc Natl Acad Sci U S A. 1998 Jan 06; 95(1):328-33. Cideciyan AV, Zhao X, Nielsen L, Khani SC, Jacobson SG, Palczewski K. PMID: 9419375; PMCID: PMC18214.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    498. Calcium binding to recoverin: implications for secondary structure and membrane association. Biochim Biophys Acta. 1997 Oct 17; 1342(2):164-74. Johnson WC, Palczewski K, Gorczyca WA, Riazance-Lawrence JH, Witkowska D, Polans AS. PMID: 9392525.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    499. GTP-binding-protein-coupled receptor kinases--two mechanistic models. Eur J Biochem. 1997 Sep 01; 248(2):261-9. Palczewski K. PMID: 9346277.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    500. Activation and inactivation steps in the visual transduction pathway. Curr Opin Neurobiol. 1997 Aug; 7(4):500-4. Palczewski K, Saari JC. PMID: 9287193.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    501. Functional differences in the interaction of arrestin and its splice variant, p44, with rhodopsin. Biochemistry. 1997 Jul 29; 36(30):9253-60. Pulvermüller A, Maretzki D, Rudnicka-Nawrot M, Smith WC, Palczewski K, Hofmann KP. PMID: 9230059.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    502. Localization of guanylate cyclase-activating protein 2 in mammalian retinas. Proc Natl Acad Sci U S A. 1997 Apr 29; 94(9):4727-32. Otto-Bruc A, Fariss RN, Haeseleer F, Huang J, Buczylko J, Surgucheva I, Baehr W, Milam AH, Palczewski K. PMID: 9114059; PMCID: PMC20792.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    503. Functional reconstitution of photoreceptor guanylate cyclase with native and mutant forms of guanylate cyclase-activating protein 1. Biochemistry. 1997 Apr 08; 36(14):4295-302. Otto-Bruc A, Buczylko J, Surgucheva I, Subbaraya I, Rudnicka-Nawrot M, Crabb JW, Arendt A, Hargrave PA, Baehr W, Palczewski K. PMID: 9100025.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    504. Molecular cloning and localization of rhodopsin kinase in the mammalian pineal. Vis Neurosci. 1997 Mar-Apr; 14(2):225-32. Zhao X, Haeseleer F, Fariss RN, Huang J, Baehr W, Milam AH, Palczewski K. PMID: 9147475.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    505. The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1). Genomics. 1997 Feb 01; 39(3):312-22. Surguchov A, Bronson JD, Banerjee P, Knowles JA, Ruiz C, Subbaraya I, Palczewski K, Baehr W. PMID: 9119368.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    506. Turned on by Ca2+! The physiology and pathology of Ca(2+)-binding proteins in the retina. Trends Neurosci. 1996 Dec; 19(12):547-54. Polans A, Baehr W, Palczewski K. PMID: 8961484.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimals
    507. Splice variants of arrestins. Exp Eye Res. 1996 Nov; 63(5):599-602. Palczewski K, Smith WC. PMID: 8994364.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    508. Mechanisms of opsin activation. J Biol Chem. 1996 Aug 23; 271(34):20621-30. Buczylko J, Saari JC, Crouch RK, Palczewski K. PMID: 8702809.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    509. Calcium modulation of bovine photoreceptor guanylate cyclase. Biochemistry. 1996 Jul 02; 35(26):8478-82. Duda T, Goraczniak R, Surgucheva I, Rudnicka-Nawrot M, Gorczyca WA, Palczewski K, Sitaramayya A, Baehr W, Sharma RK. PMID: 8679607.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    510. Responses of the phototransduction cascade to dim light. Proc Natl Acad Sci U S A. 1996 May 14; 93(10):4677-82. Langlois G, Chen CK, Palczewski K, Hurley JB, Vuong TM. PMID: 8643463; PMCID: PMC39338.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    511. Expression of GCAP1 and GCAP2 in the retinal degeneration (rd) mutant chicken retina. FEBS Lett. 1996 Apr 29; 385(1-2):47-52. Semple-Rowland SL, Gorczyca WA, Buczylko J, Helekar BS, Ruiz CC, Subbaraya I, Palczewski K, Baehr W. PMID: 8641465.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    512. Opsin/all-trans-retinal complex activates transducin by different mechanisms than photolyzed rhodopsin. Biochemistry. 1996 Mar 05; 35(9):2901-8. Jäger S, Palczewski K, Hofmann KP. PMID: 8608127.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    513. Structural and enzymatic aspects of rhodopsin phosphorylation. J Biol Chem. 1996 Mar 01; 271(9):5215-24. Ohguro H, Rudnicka-Nawrot M, Buczylko J, Zhao X, Taylor JA, Walsh KA, Palczewski K. PMID: 8617805.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    514. Alligator rhodopsin: sequence and biochemical properties. Exp Eye Res. 1995 Nov; 61(5):569-78. Smith WC, Adamus G, Van Der Wel H, Timmers A, Palczewski K, Ulshafer RJ, Hargrave PA, McDowell JH. PMID: 8654500.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    515. Guanylyl cyclase activating protein. A calcium-sensitive regulator of phototransduction. J Biol Chem. 1995 Sep 15; 270(37):22029-36. Gorczyca WA, Polans AS, Surgucheva IG, Subbaraya I, Baehr W, Palczewski K. PMID: 7665624.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    516. Mechanism of rhodopsin phosphorylation. Biophys Chem. 1995 Sep-Oct; 56(1-2):183-8. Zhao X, Palczewski K, Ohguro H. PMID: 7662865.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    517. Separation of phospho- and non-phosphopeptides using reverse phase column chromatography. FEBS Lett. 1995 Jul 24; 368(3):452-4. Ohguro H, Palczewski K. PMID: 7635197.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    518. Rhodopsin kinase autophosphorylation. Characterization of site-specific mutations. J Biol Chem. 1995 Jun 23; 270(25):15294-8. Palczewski K, Ohguro H, Premont RT, Inglese J. PMID: 7797516.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    519. Rhodopsin phosphorylation and dephosphorylation in vivo. J Biol Chem. 1995 Jun 16; 270(24):14259-62. Ohguro H, Van Hooser JP, Milam AH, Palczewski K. PMID: 7782279.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    520. Localization of three genes expressed in retina on mouse chromosome 11. Mamm Genome. 1995 Feb; 6(2):142-4. Kozak CA, Danciger M, Bowes C, Adamson MC, Palczewski K, Polans AS, Farber DB. PMID: 7767000.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    521. Molecular characterization of human and mouse photoreceptor guanylate cyclase-activating protein (GCAP) and chromosomal localization of the human gene. J Biol Chem. 1994 Dec 09; 269(49):31080-9. Subbaraya I, Ruiz CC, Helekar BS, Zhao X, Gorczyca WA, Pettenati MJ, Rao PN, Palczewski K, Baehr W. PMID: 7983048.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    522. Topographic study of arrestin using differential chemical modifications and hydrogen/deuterium exchange. Protein Sci. 1994 Dec; 3(12):2428-34. Ohguro H, Palczewski K, Walsh KA, Johnson RS. PMID: 7756996; PMCID: PMC2142757.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    523. Rod outer segment retinol dehydrogenase: substrate specificity and role in phototransduction. Biochemistry. 1994 Nov 22; 33(46):13741-50. Palczewski K, Jäger S, Buczylko J, Crouch RK, Bredberg DL, Hofmann KP, Asson-Batres MA, Saari JC. PMID: 7947785.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    524. Inositolhexakisphosphate (InsP6): an antagonist of fibroblast growth factor receptor binding and activity. In Vitro Cell Dev Biol Anim. 1994 Nov; 30A(11):783-9. Morrison RS, Shi E, Kan M, Yamaguchi F, McKeehan W, Rudnicka-Nawrot M, Palczewski K. PMID: 7881632.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    525. Is vertebrate phototransduction solved? New insights into the molecular mechanism of phototransduction. Invest Ophthalmol Vis Sci. 1994 Sep; 35(10):3577-81. Palczewski K. PMID: 7522225.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    526. Structure and functions of arrestins. Protein Sci. 1994 Sep; 3(9):1355-61. Palczewski K. PMID: 7833798; PMCID: PMC2142942.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    527. Heterogeneous N-acylation is a tissue- and species-specific posttranslational modification. J Biol Chem. 1994 Aug 19; 269(33):21067-71. Johnson RS, Ohguro H, Palczewski K, Hurley JB, Walsh KA, Neubert TA. PMID: 8063726.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    528. Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase-activating protein. Neuron. 1994 Aug; 13(2):395-404. Palczewski K, Subbaraya I, Gorczyca WA, Helekar BS, Ruiz CC, Ohguro H, Huang J, Zhao X, Crabb JW, Johnson RS, et al. PMID: 7520254.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansAnimalsCells
    529. Opsins with mutations at the site of chromophore attachment constitutively activate transducin but are not phosphorylated by rhodopsin kinase. Proc Natl Acad Sci U S A. 1994 Jun 07; 91(12):5411-5. Robinson PR, Buczylko J, Ohguro H, Palczewski K. PMID: 8202499; PMCID: PMC44005.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    530. A splice variant of arrestin. Molecular cloning and localization in bovine retina. J Biol Chem. 1994 Jun 03; 269(22):15407-10. Smith WC, Milam AH, Dugger D, Arendt A, Hargrave PA, Palczewski K. PMID: 7515057.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    531. Purification and physiological evaluation of a guanylate cyclase activating protein from retinal rods. Proc Natl Acad Sci U S A. 1994 Apr 26; 91(9):4014-8. Gorczyca WA, Gray-Keller MP, Detwiler PB, Palczewski K. PMID: 7909609; PMCID: PMC43713.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    532. Nucleotide inhibitors and activators of retinal guanylyl cyclase. Biochemistry. 1994 Mar 22; 33(11):3217-22. Gorczyca WA, Van Hooser JP, Palczewski K. PMID: 7511001.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    533. Purification and primary structure of Capl, an S-100-related calcium-binding protein isolated from bovine retina. J Biol Chem. 1994 Feb 25; 269(8):6233-40. Polans AS, Palczewski K, Asson-Batres MA, Ohguro H, Witkowska D, Haley TL, Baizer L, Crabb JW. PMID: 8119967.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    534. Characterization of a truncated form of arrestin isolated from bovine rod outer segments. Protein Sci. 1994 Feb; 3(2):314-24. Palczewski K, Buczylko J, Ohguro H, Annan RS, Carr SA, Crabb JW, Kaplan MW, Johnson RS, Walsh KA. PMID: 8003967; PMCID: PMC2142797.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    535. Control of rhodopsin multiple phosphorylation. Biochemistry. 1994 Feb 01; 33(4):1023-8. Ohguro H, Johnson RS, Ericsson LH, Walsh KA, Palczewski K. PMID: 8305429.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    536. Interaction between photoactivated rhodopsin and its kinase: stability and kinetics of complex formation. Biochemistry. 1993 Dec 28; 32(51):14082-8. Pulvermüller A, Palczewski K, Hofmann KP. PMID: 8260489.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    537. Assays of retinoid dehydrogenases by phase partition. Anal Biochem. 1993 Aug 15; 213(1):128-32. Saari JC, Bredberg DL, Garwin GG, Buczylko J, Wheeler T, Palczewski K. PMID: 8238865.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    538. The kinetics of multiphosphorylation of rhodopsin. Arch Biochem Biophys. 1993 Aug 01; 304(2):443-7. Adamus G, Arendt A, Hargrave PA, Heyduk T, Palczewski K. PMID: 8346919.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    539. Sequential phosphorylation of rhodopsin at multiple sites. Biochemistry. 1993 Jun 01; 32(21):5718-24. Ohguro H, Palczewski K, Ericsson LH, Walsh KA, Johnson RS. PMID: 8504090.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    540. Beta-arrestin and arrestin are recognized by autoantibodies in sera from multiple sclerosis patients. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3241-5. Ohguro H, Chiba S, Igarashi Y, Matsumoto H, Akino T, Palczewski K. PMID: 8475065; PMCID: PMC46275.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    541. Basic fibroblast growth factor expression is required for clonogenic growth of human glioma cells. J Neurosci Res. 1993 Apr 01; 34(5):502-9. Morrison RS, Giordano S, Yamaguchi F, Hendrickson S, Berger MS, Palczewski K. PMID: 8478985.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    542. Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin. J Biol Chem. 1993 Mar 15; 268(8):6004-13. Palczewski K, Buczylko J, Lebioda L, Crabb JW, Polans AS. PMID: 8383684.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    543. The effect of recoverin-like calcium-binding proteins on the photoresponse of retinal rods. Neuron. 1993 Mar; 10(3):523-31. Gray-Keller MP, Polans AS, Palczewski K, Detwiler PB. PMID: 8461139.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    544. Recoverin, but not visinin, is an autoantigen in the human retina identified with a cancer-associated retinopathy. Invest Ophthalmol Vis Sci. 1993 Jan; 34(1):81-90. Polans AS, Burton MD, Haley TL, Crabb JW, Palczewski K. PMID: 8425844.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    545. Identification of the autophosphorylation sites in rhodopsin kinase. J Biol Chem. 1992 Sep 15; 267(26):18991-8. Palczewski K, Buczylko J, Van Hooser P, Carr SA, Huddleston MJ, Crabb JW. PMID: 1527025.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    546. The role of arrestin and retinoids in the regeneration pathway of rhodopsin. J Biol Chem. 1992 Aug 05; 267(22):15701-6. Hofmann KP, Pulvermüller A, Buczylko J, Van Hooser P, Palczewski K. PMID: 1386362.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    547. Structural properties of arrestin studied by chemical modification and circular dichroism. Biochemistry. 1992 Apr 28; 31(16):3902-6. Palczewski K, Riazance-Lawrence JH, Johnson WC. PMID: 1567843.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    548. The influence of arrestin (48K protein) and rhodopsin kinase on visual transduction. Neuron. 1992 Jan; 8(1):117-26. Palczewski K, Rispoli G, Detwiler PB. PMID: 1309646.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    549. Binding of inositol phosphates to arrestin. FEBS Lett. 1991 Dec 16; 295(1-3):195-9. Palczewski K, Pulvermüller A, Buczylko J, Gutmann C, Hofmann KP. PMID: 1765153.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    550. Phosphorylated rhodopsin and heparin induce similar conformational changes in arrestin. J Biol Chem. 1991 Oct 05; 266(28):18649-54. Palczewski K, Pulvermüller A, Buczylko J, Hofmann KP. PMID: 1917988.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    551. The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase. Proc Natl Acad Sci U S A. 1991 Oct 01; 88(19):8715-9. Lorenz W, Inglese J, Palczewski K, Onorato JJ, Caron MG, Lefkowitz RJ. PMID: 1656454; PMCID: PMC52580.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    552. G-protein-coupled receptor kinases. Trends Biochem Sci. 1991 Oct; 16(10):387-91. Palczewski K, Benovic JL. PMID: 1664548.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    553. Role of the carboxyl-terminal region of arrestin in binding to phosphorylated rhodopsin. J Biol Chem. 1991 Aug 15; 266(23):15334-9. Palczewski K, Buczylko J, Imami NR, McDowell JH, Hargrave PA. PMID: 1651326.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    554. Mechanism of rhodopsin kinase activation. J Biol Chem. 1991 Jul 15; 266(20):12949-55. Palczewski K, Buczylko J, Kaplan MW, Polans AS, Crabb JW. PMID: 2071581.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    555. Elevated level of protein phosphatase 2A activity in retinas of rd mice. Exp Eye Res. 1991 Jul; 53(1):101-5. Palczewski K, Farber DB, Hargrave PA. PMID: 1652453.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    556. Properties of solubilized and reconstituted A1 adenosine receptors from bovine brain. Pharmacol Res. 1991 Jul; 24(1):15-23. Ragazzi E, Shryock J, Palczewski K. PMID: 1946140.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    557. Role of acidic amino acids in peptide substrates of the beta-adrenergic receptor kinase and rhodopsin kinase. Biochemistry. 1991 May 28; 30(21):5118-25. Onorato JJ, Palczewski K, Regan JW, Caron MG, Lefkowitz RJ, Benovic JL. PMID: 1645191.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    558. Regulation of rhodopsin kinase by autophosphorylation. Proc Natl Acad Sci U S A. 1991 Mar 15; 88(6):2568-72. Buczylko J, Gutmann C, Palczewski K. PMID: 2006192; PMCID: PMC51274.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    559. Studies of ligand binding to arrestin. J Biol Chem. 1991 Mar 05; 266(7):4201-6. Palczewski K, Hargrave PA. PMID: 1999413.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    560. A photoreceptor calcium binding protein is recognized by autoantibodies obtained from patients with cancer-associated retinopathy. J Cell Biol. 1991 Mar; 112(5):981-9. Polans AS, Buczylko J, Crabb J, Palczewski K. PMID: 1999465; PMCID: PMC2288874.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    561. Anti-rhodopsin monoclonal antibodies of defined specificity: characterization and application. Vision Res. 1991; 31(1):17-31. Adamus G, Zam ZS, Arendt A, Palczewski K, McDowell JH, Hargrave PA. PMID: 2006550.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    562. Phosphorylation of iodopsin, chicken red-sensitive cone visual pigment. Biochemistry. 1990 Oct 30; 29(43):10102-6. Fukada Y, Kokame K, Okano T, Shichida Y, Yoshizawa T, McDowell JH, Hargrave PA, Palczewski K. PMID: 2271641.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    563. Nucleoside inhibitors of rhodopsin kinase. Biochemistry. 1990 Jul 03; 29(26):6276-82. Palczewski K, Kahn N, Hargrave PA. PMID: 2207073.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    564. X-ray crystal structure of sangivamycin, a potent inhibitor of protein kinases. FEBS Lett. 1990 Jun 18; 266(1-2):102-4. Lebioda L, Hargrave PA, Palczewski K. PMID: 2365059.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    565. Synthetic phosphopeptides are substrates for casein kinase II. FEBS Lett. 1990 Feb 12; 261(1):117-20. Litchfield DW, Arendt A, Lozeman FJ, Krebs EG, Hargrave PA, Palczewski K. PMID: 2307228.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    566. Molecular, enzymatic and functional properties of rhodopsin kinase from rat pineal gland. Vision Res. 1990; 30(8):1129-37. Palczewski K, Carruth ME, Adamus G, McDowell JH, Hargrave PA. PMID: 2402884.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    567. Substrate recognition determinants for rhodopsin kinase: studies with synthetic peptides, polyanions, and polycations. Biochemistry. 1989 Oct 31; 28(22):8764-70. Palczewski K, Arendt A, McDowell JH, Hargrave PA. PMID: 2605220.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    568. Regulation of rhodopsin dephosphorylation by arrestin. J Biol Chem. 1989 Sep 25; 264(27):15770-3. Palczewski K, McDowell JH, Jakes S, Ingebritsen TS, Hargrave PA. PMID: 2550422.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    569. Synthesis of phosphopeptides containing O-phosphoserine or O-phosphothreonine. Int J Pept Protein Res. 1989 Jun; 33(6):468-76. Arendt A, Palczewski K, Moore WT, Caprioli RM, McDowell JH, Hargrave PA. PMID: 2506143.
      View in: PubMed   Mentions: 2     Fields:    
    570. The catalytic subunit of phosphatase 2A dephosphorylates phosphoopsin. Biochemistry. 1989 Jan 24; 28(2):415-9. Palczewski K, Hargrave PA, McDowell JH, Ingebritsen TS. PMID: 2540796.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    571. Purification and characterization of rhodopsin kinase. J Biol Chem. 1988 Oct 05; 263(28):14067-73. Palczewski K, McDowell JH, Hargrave PA. PMID: 2844754.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    572. Rhodopsin kinase: substrate specificity and factors that influence activity. Biochemistry. 1988 Apr 05; 27(7):2306-13. Palczewski K, McDowell JH, Hargrave PA. PMID: 3382623.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    573. Photoaffinity labeling of rabbit muscle fructose-1,6-bisphosphate aldolase with 8-azido-1,N6-ethenoadenosine 5'-triphosphate. Biochemistry. 1987 Jun 16; 26(12):3466-71. Palczewski K, Kochman M. PMID: 3651392.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    574. Affinity labeling of rabbit muscle fructose-1,6-bisphosphate aldolase with 5'-[p-(fluorosulfonyl)benzoyl]-1,N6-ethenoadenosine. Eur J Biochem. 1985 Jan 15; 146(2):309-14. Palczewski K, Hargrave PA, Folta EJ, Kochman M. PMID: 3967660.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    575. o-Phthalaldehyde, a fluorescence probe of aldolase active site. Eur J Biochem. 1983 Dec 15; 137(3):429-35. Palczewski K, Hargrave PA, Kochman M. PMID: 6662105.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    With one click, see people who:

    Run Clinical Trials

    See more options in the Advanced Search tab

    Krzysztof's Networks
    Concepts (1240)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (27)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCI Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).
    This site is running Profiles RNS version UCSF-v3.1.0-3-g1ef1264b on PROFILES-PWEB04. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California