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Mathew Mark Blurton-Jones

Title(s)Associate Professor, Neurobiology & Behavior
SchoolSchool of Biological Sciences
AddressZot 1695
Irvine CA 92697
Phone(949) 824-5243
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    A novel platform for the investigation of human microglia
    NIH RF1DA048813Aug 15, 2019 - Aug 14, 2022
    Role: Co-Principal Investigator
    Examining the role of adaptive immunity in Alzheimer's Disease pathogenesis
    NIH RF1AG055524Sep 15, 2017 - Mar 31, 2022
    Role: Principal Investigator
    Manipulating DNA repair enzymes to examine the interactions between aging and Alzheimers disease with iPSC-derived microglia
    NIH R01AG056303Jul 15, 2017 - Apr 30, 2022
    Role: Principal Investigator
    The role of TREM2 in human microglial function and Alzheimer disease pathogenesis
    NIH RF1AG048099Sep 15, 2014 - Jun 30, 2019
    Role: Principal Investigator
    The Role of Beta-Amyloid Assembly States in Tau Pathology and Cognitive Decline
    NIH K01AG029378Apr 15, 2008 - Mar 31, 2013
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Transplantation of Human IPSC-derived Microglia Ameliorates Neuropathology and Circuit Dysfunction in Progranulin-Deficient Mice. bioRxiv. 2026 Jan 13. Davtyan H, Naguib S, Voskobiynyk Y, Chadarevian JP, Capocchi JK, Giacchino JL, Eskandari-Sedighi G, DeNittis V, Ford JB, Agababian A, Nguyen J, Chadarevian AL, Sutherland MS, Shabestari SK, Nana AL, Zhang J, Spina S, Wong MY, Grinberg LT, Seeley WW, Huang E, Clelland CD, Gong S, Fan L, Paz JT, Blurton-Jones M, Gan L. PMID: 41648346; PMCID: PMC12871286.
      View in: PubMed   Mentions:
    2. PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation. bioRxiv. 2025 Dec 19. Deyell JS, Hasselmann J, Stroud L, Raychaudhuri U, Guo Y, Cha B, Karma C, Tendean D, Tran MV, Gromova A, Dickey AS, Blurton-Jones M, La Spada AR. PMID: 41446071; PMCID: PMC12724615.
      View in: PubMed   Mentions:
    3. Human iPSC-derived APOE4/4 Alzheimer´s disease astrocytes exhibit a senescent and pro-inflammatory state that compromises neuronal support. J Neuroinflammation. 2025 Dec 12; 23(1):9. Caceres-Palomo L, Sanchez-Mejias E, Trujillo-Estrada L, Perez-Moreno JJ, Lopez-Oliva E, Lim TE, DeFlitch L, Chang SH, Kampman L, Corces MR, Blurton-Jones M, Moreno-Gonzalez I, Pascual A, Vitorica J, Garcia-Leon JA, Gutierrez A. PMID: 41388301; PMCID: PMC12781401.
      View in: PubMed   Mentions:    Fields:    
    4. Loss of PILRA promotes microglial immunometabolism to reduce amyloid pathology in cell and mouse models of Alzheimer's disease. Sci Transl Med. 2025 Dec 03; 17(827):eadw7428. Weerakkody TN, Sabelström H, Andrews SV, Chadarevian JP, Chin MY, Tatarakis D, Propson NE, Kim DJ, Theolis R, Parico GCG, Misker H, Kung JE, Bandyopadhyay A, Robles Colmenares Y, Jackson TN, Qerqez AN, Balasundar S, Davis SS, Ha C, Ghosh R, Ravi R, Rana A, Germain K, Tao A, Xiong K, Braun D, Raju K, Huang KC, Zhan L, Guo JL, Safari Yazd H, Sarrafha L, Capocchi JK, Hasselmann J, Chadarevian AL, Tu C, Mansour K, Eskandari-Sedighi G, Tesi N, van der Lee S, Hulsman M, Oshegov G, Pijnenburg Y, Calvert M, Holstege H, Suh JH, Di Paolo G, Davtyan H, Lewcock JW, Blurton-Jones M, Monroe KM. PMID: 41337541.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    5. CSF1R inhibitor-resistant model for CNS-wide microglia replacement strategies. Mol Ther. 2026 Feb 04; 34(2):832-849. Chadarevian JP, Nguyen J, Le L, Ayala LA, Chadarevian AL, Zhou C, Escobar A, Do AT, Deynega E, Mansour K, Hasselmann J, Eskandari-Sedighi G, Lombroso SI, Bennett FC, Inlay MA, Davtyan H, Blurton-Jones M. PMID: 41232524; PMCID: PMC12882379.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Microglia replacement by peripheral delivery of CSF1R inhibitor-resistant hematopoietic cells. Mol Ther. 2026 Feb 04; 34(2):850-866. Lombroso SI, Church EI, Anderson RN, O'Brien CA, Zhu Y, Dar AA, Purnell FS, Levitt EM, Temsamrit B, Yaqoob F, Aisenberg WH, Davis M, Elfayoumi B, Chaluvadi S, Nemec KM, Axsom J, Shapiro DA, Oon CH, Chadarevian JP, Assenmacher CA, De Arcangeli S, Banerjee E, Shukla S, Davtyan H, Bailis W, Hunter CA, Blurton-Jones M, Bennett ML, Haney MS, Bennett FC. PMID: 41232525; PMCID: PMC12704446.
      View in: PubMed   Mentions:
    7. Human microglia differentially respond to β-amyloid, tau, and combined Alzheimer's disease pathologies in vivo. Alzheimers Dement. 2025 Nov; 21(11):e70930. Coburn MA, Eskandari-Sedighi G, Hasselmann J, England W, Shabestari SK, Mansour K, McQuade A, Mgerian MA, Chadarevian JP, Tu C, Silva J, Beck J, Keulen Z, Spitale RC, Davtyan H, Blurton-Jones M. PMID: 41268790; PMCID: PMC12635866.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    8. Amyloid precursor protein and C99 are subunits in human microglial Hv1 channels that enhance current and inflammatory mediator release. Proc Natl Acad Sci U S A. 2025 Oct 28; 122(43):e2509903122. Zhao R, Sophanpanichkul P, Chadarevian JP, Ding Y, Dai H, Nayak M, Davtyan H, Blurton-Jones M, Goldstein SAN. PMID: 41129234; PMCID: PMC12582281.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Microglia-specific regulation of lipid metabolism in Alzheimer's disease revealed by microglial depletion in 5xFAD Mice. Nat Commun. 2025 Oct 15; 16(1):9156. Xu Z, Kiani Shabestari S, Barannikov S, Bieniek KF, Blurton-Jones M, Palavicini JP, Han X. PMID: 41093842; PMCID: PMC12528747.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    10. Brain wide engraftment of human monocytes induces neurodegeneration and cognitive dysfunction. Res Sq. 2025 Oct 10. Blurton-Jones M, Davtyan H, Chadarevian JP, Lakatos A, Lin S, Hasselmann J, Nguyen J, Duong D, Capocchi J, Lahian A, Mansour K, Eskandari-Sedighi G, Tu C, Shabestari SK, Wu F, Shantaraman A, Mgerian M, Lim T, Mai A, Le L, Agababian A, Head E, Datta SR, Seyfried N. PMID: 41282056; PMCID: PMC12632712.
      View in: PubMed   Mentions:
    11. Cerebrovascular alterations in a mouse model of late-onset Alzheimer's disease. Neurophotonics. 2025 Jan; 12(Suppl 1):S14614. Crouzet C, Xie DF, Laquindanum Nuqui MN, Hasselman J, Phan T, Wilson RH, Baglietto-Vargas D, Da Cunha C, Davtyan H, Forner S, Jullienne A, Bazrafkan A, LaFerla FM, Obenaus A, Blurton-Jones M, Akbari Y, Green KN, Choi B. PMID: 40475700; PMCID: PMC12138534.
      View in: PubMed   Mentions: 1  
    12. Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins. Cell Stem Cell. 2025 Jun 05; 32(6):914-934.e8. Chadarevian JP, Davtyan H, Chadarevian AL, Nguyen J, Capocchi JK, Le L, Escobar A, Chadarevian T, Mansour K, Deynega E, Mgerian M, Tu C, Kiani Shabestari S, Carlen-Jones W, Eskandari-Sedighi G, Hasselmann J, Spitale RC, Blurton-Jones M. PMID: 40233761; PMCID: PMC12360426.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    13. Immune checkpoint TIM-3 regulates microglia and Alzheimer's disease. Nature. 2025 May; 641(8063):718-731. Kimura K, Subramanian A, Yin Z, Khalilnezhad A, Wu Y, He D, Dixon KO, Chitta UK, Ding X, Adhikari N, Guzchenko I, Zhang X, Tang R, Pertel T, Myers SA, Aastha A, Nomura M, Eskandari-Sedighi G, Singh V, Liu L, Lambden C, Kleemann KL, Gupta N, Barry JL, Durao A, Cheng Y, Silveira S, Zhang H, Suhail A, Delorey T, Rozenblatt-Rosen O, Freeman GJ, Selkoe DJ, Weiner HL, Blurton-Jones M, Cruchaga C, Regev A, Suvà ML, Butovsky O, Kuchroo VK. PMID: 40205047; PMCID: PMC12079183.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    14. Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins. Cell Stem Cell. 2025 Apr 09. Chadarevian JP, Davtyan H, Chadarevian AL, Nguyen J, Capocchi JK, Le L, Escobar A, Chadarevian T, Mansour K, Deynega E, Mgerian M, Tu C, Kiani Shabestari S, Carlen-Jones W, Eskandari-Sedighi G, Hasselmann J, Spitale RC, Blurton-Jones M. PMID: 40233761.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    15. Retraction Note: Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies. NPJ Vaccines. 2025 Mar 12; 10(1):47. Kim C, Hovakimyan A, Zagorski K, Antonyan T, Petrushina I, Davtyan H, Chailyan G, Hasselmann J, Iba M, Adame A, Rockenstein E, Szabo M, Blurton-Jones M, Cribbs DH, Ghochikyan A, Masliah E, Agadjanyan MG. PMID: 40074745; PMCID: PMC11903769.
      View in: PubMed   Mentions:
    16. Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy. Sci Transl Med. 2025 Jan 15; 17(781):eadk3690. Brandao W, Jain N, Yin Z, Kleemann KL, Carpenter M, Bao X, Serrano JR, Tycksen E, Durao A, Barry JL, Baufeld C, Guneykaya D, Zhang X, Litvinchuk A, Jiang H, Rosenzweig N, Pitts KM, Aronchik M, Yahya T, Cao T, Takahashi MK, Krishnan R, Davtyan H, Ulrich JD, Blurton-Jones M, Ilin I, Weiner HL, Holtzman DM, Butovsky O. PMID: 39813317; PMCID: PMC13006031.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    17. Microglial APOE3 Christchurch protects neurons from Tau pathology in a human iPSC-based model of Alzheimer's disease. Cell Rep. 2024 12 24; 43(12):114982. Sun GG, Wang C, Mazzarino RC, Perez-Corredor PA, Davtyan H, Blurton-Jones M, Lopera F, Arboleda-Velasquez JF, Shi Y. PMID: 39612244; PMCID: PMC11753789.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    18. Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism. Neuron. 2024 Sep 04; 112(17):2910-2921.e7. Profaci CP, Harvey SS, Bajc K, Zhang TZ, Jeffrey DA, Zhang AZ, Nemec KM, Davtyan H, O'Brien CA, McKinsey GL, Longworth A, McMullen TP, Capocchi JK, Gonzalez JG, Lawson DA, Arnold TD, Davalos D, Blurton-Jones M, Dabertrand F, Bennett FC, Daneman R. PMID: 39142282; PMCID: PMC11446403.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    19. Organelle phenotyping and multi-dimensional microscopy identify C1q as a novel regulator of microglial function. J Neurochem. 2024 09; 168(9):3095-3107. Sakthivel PS, Scipioni L, Karam J, Keulen Z, Blurton-Jones M, Gratton E, Anderson AJ. PMID: 39018376; PMCID: PMC11449638.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    20. Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease. Nat Med. 2024 Oct; 30(10):2990-3003. Rosenzweig N, Kleemann KL, Rust T, Carpenter M, Grucci M, Aronchik M, Brouwer N, Valenbreder I, Cooper-Hohn J, Iyer M, Krishnan RK, Sivanathan KN, Brandão W, Yahya T, Durao A, Yin Z, Chadarevian JP, Properzi MJ, Nowarski R, Davtyan H, Weiner HL, Blurton-Jones M, Yang HS, Eggen BJL, Sperling RA, Butovsky O. PMID: 38961225; PMCID: PMC12952287.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    21. Microglia protect against age-associated brain pathologies. Neuron. 2024 Aug 21; 112(16):2732-2748.e8. Munro DAD, Bestard-Cuche N, McQuaid C, Chagnot A, Shabestari SK, Chadarevian JP, Maheshwari U, Szymkowiak S, Morris K, Mohammad M, Corsinotti A, Bradford B, Mabbott N, Lennen RJ, Jansen MA, Pridans C, McColl BW, Keller A, Blurton-Jones M, Montagne A, Williams A, Priller J. PMID: 38897208.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    22. Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy. Neuron. 2024 Aug 21; 112(16):2686-2707.e8. Chadarevian JP, Hasselmann J, Lahian A, Capocchi JK, Escobar A, Lim TE, Le L, Tu C, Nguyen J, Kiani Shabestari S, Carlen-Jones W, Gandhi S, Bu G, Hume DA, Pridans C, Wszolek ZK, Spitale RC, Davtyan H, Blurton-Jones M. PMID: 38897209; PMCID: PMC12357648.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    23. ER and SOCE Ca2+ signals are not required for directed cell migration in human iPSC-derived microglia. Cell Calcium. 2024 Nov; 123:102923. Granzotto A, McQuade A, Chadarevian JP, Davtyan H, Sensi SL, Parker I, Blurton-Jones M, Smith IF. PMID: 38970922; PMCID: PMC12424127.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    24. Correction: Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models. Stem Cell Res Ther. 2024 Mar 25; 15(1):88. Blurton-Jones M, Spencer B, Michael S, Castello NA, Agazaryan AA, Davis JL, Müller FJ, Loring JF, Masliah E, LaFerla FM. PMID: 38523285; PMCID: PMC10962161.
      View in: PubMed   Mentions:    Fields:    
    25. Genetic contribution to microglial activation in schizophrenia. Mol Psychiatry. 2024 Sep; 29(9):2622-2633. Koskuvi M, Pörsti E, Hewitt T, Räsänen N, Wu YC, Trontti K, McQuade A, Kalyanaraman S, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Blurton-Jones M, Hovatta I, Lähteenvuo M, Rolova T, Lehtonen Š, Tiihonen J, Koistinaho J. PMID: 38519640; PMCID: PMC11420079.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    26. Neurotoxic Microglial Activation via IFNγ-Induced Nrf2 Reduction Exacerbating Alzheimer's Disease. Adv Sci (Weinh). 2024 05; 11(20):e2304357. Kang YJ, Hyeon SJ, McQuade A, Lim J, Baek SH, Diep YN, Do KV, Jeon Y, Jo DG, Lee CJ, Blurton-Jones M, Ryu H, Cho H. PMID: 38482922; PMCID: PMC11132036.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    27. ER and SOCE Ca2+ signals are not required for directed cell migration in human microglia. bioRxiv. 2024 Jan 19. Granzotto A, McQuade A, Chadarevian JP, Davtyan H, Sensi SL, Parker I, Blurton-Jones M, Smith I. PMID: 38293075; PMCID: PMC10827168.
      View in: PubMed   Mentions:
    28. Microglial APOE4: more is less and less is more. Mol Neurodegener. 2023 12 19; 18(1):99. Eskandari-Sedighi G, Blurton-Jones M. PMID: 38115077; PMCID: PMC10729371.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    29. Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis. Nat Cell Biol. 2023 12; 25(12):1848-1859. Evans KT, Blake K, Longworth A, Coburn MA, Insua-Rodríguez J, McMullen TP, Nguyen QH, Ma D, Lev T, Hernandez GA, Oganyan AK, Orujyan D, Edwards RA, Pridans C, Green KN, Villalta SA, Blurton-Jones M, Lawson DA. PMID: 37957324; PMCID: PMC11414741.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    30. Human microglia maturation is underpinned by specific gene regulatory networks. Immunity. 2023 09 12; 56(9):2152-2171.e13. Han CZ, Li RZ, Hansen E, Trescott S, Fixsen BR, Nguyen CT, Mora CM, Spann NJ, Bennett HR, Poirion O, Buchanan J, Warden AS, Xia B, Schlachetzki JCM, Pasillas MP, Preissl S, Wang A, O'Connor C, Shriram S, Kim R, Schafer D, Ramirez G, Challacombe J, Anavim SA, Johnson A, Gupta M, Glass IA, Birth Defects Research Laboratory, Levy ML, Haim SB, Gonda DD, Laurent L, Hughes JF, Page DC, Blurton-Jones M, Glass CK, Coufal NG. PMID: 37582369; PMCID: PMC10529991.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    31. Mitochondria dysregulation contributes to secondary neurodegeneration progression post-contusion injury in human 3D in vitro triculture brain tissue model. Cell Death Dis. 2023 08 03; 14(8):496. Liaudanskaya V, Fiore NJ, Zhang Y, Milton Y, Kelly MF, Coe M, Barreiro A, Rose VK, Shapiro MR, Mullis AS, Shevzov-Zebrun A, Blurton-Jones M, Whalen MJ, Symes AJ, Georgakoudi I, Nieland TJF, Kaplan DL. PMID: 37537168; PMCID: PMC10400598.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    32. Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3. Brain Behav Immun. 2023 10; 113:353-373. Haukedal H, Syshøj Lorenzen S, Winther Westi E, Corsi GI, Gadekar VP, McQuade A, Davtyan H, Doncheva NT, Schmid B, Chandrasekaran A, Seemann SE, Cirera S, Blurton-Jones M, Meyer M, Gorodkin J, Aldana BI, Freude K. PMID: 37543250.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    33. CRISPR generation of CSF1R-G795A human microglia for robust microglia replacement in a chimeric mouse model. STAR Protoc. 2023 09 15; 4(3):102490. Chadarevian JP, Davtyan H, Lombroso SI, Bennett FC, Blurton-Jones M. PMID: 37516973; PMCID: PMC10407259.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    34. Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro. Nat Immunol. 2023 08; 24(8):1382-1390. Dolan MJ, Therrien M, Jereb S, Kamath T, Gazestani V, Atkeson T, Marsh SE, Goeva A, Lojek NM, Murphy S, White CM, Joung J, Liu B, Limone F, Eggan K, Hacohen N, Bernstein BE, Glass CK, Leinonen V, Blurton-Jones M, Zhang F, Epstein CB, Macosko EZ, Stevens B. PMID: 37500887; PMCID: PMC10382323.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    35. Astrocytic response mediated by the CLU risk allele inhibits OPC proliferation and myelination in a human iPSC model. Cell Rep. 2023 08 29; 42(8):112841. Liu Z, Chao J, Wang C, Sun G, Roeth D, Liu W, Chen X, Li L, Tian E, Feng L, Davtyan H, Blurton-Jones M, Kalkum M, Shi Y. PMID: 37494190; PMCID: PMC10510531.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    36. Author Correction: Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies. NPJ Vaccines. 2023 Jul 17; 8(1):105. Kim C, Hovakimyan A, Zagorski K, Antonyan T, Petrushina I, Davtyan H, Chailyan G, Hasselmann J, Iba M, Adame A, Rockenstein E, Szabo M, Blurton-Jones M, Cribbs DH, Ghochikyan A, Masliah E, Agadjanyan MG. PMID: 37460684; PMCID: PMC10352336.
      View in: PubMed   Mentions:
    37. Novel Vaccine against Pathological Pyroglutamate-Modified Amyloid Beta for Prevention of Alzheimer's Disease. Int J Mol Sci. 2023 Jun 06; 24(12). Zagorski K, King O, Hovakimyan A, Petrushina I, Antonyan T, Chailyan G, Ghazaryan M, Hyrc KL, Chadarevian JP, Davtyan H, Blurton-Jones M, Cribbs DH, Agadjanyan MG, Ghochikyan A. PMID: 37372944; PMCID: PMC10298272.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    38. Moderate intrinsic phenotypic alterations in C9orf72 ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features. Front Cell Neurosci. 2023; 17:1179796. Lorenzini I, Alsop E, Levy J, Gittings LM, Lall D, Rabichow BE, Moore S, Pevey R, Bustos LM, Burciu C, Bhatia D, Singer M, Saul J, McQuade A, Tzioras M, Mota TA, Logemann A, Rose J, Almeida S, Gao FB, Marks M, Donnelly CJ, Hutchins E, Hung ST, Ichida J, Bowser R, Spires-Jones T, Blurton-Jones M, Gendron TF, Baloh RH, Van Keuren-Jensen K, Sattler R. PMID: 37346371; PMCID: PMC10279871.
      View in: PubMed   Mentions: 13  
    39. Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nat Commun. 2023 Mar 02; 14(1):1194. McQuade A, Kang YJ, Hasselmann J, Jairaman A, Sotelo A, Coburn M, Shabestari SK, Chadarevian JP, Fote G, Tu CH, Danhash E, Silva J, Martinez E, Cotman C, Prieto GA, Thompson LM, Steffan JS, Smith I, Davtyan H, Cahalan M, Cho H, Blurton-Jones M. PMID: 36864071; PMCID: PMC9981556.
      View in: PubMed   Mentions:    Fields:    
    40. Engineering an inhibitor-resistant human CSF1R variant for microglia replacement. J Exp Med. 2023 03 06; 220(3). Chadarevian JP, Lombroso SI, Peet GC, Hasselmann J, Tu C, Marzan DE, Capocchi J, Purnell FS, Nemec KM, Lahian A, Escobar A, England W, Chaluvadi S, O'Brien CA, Yaqoob F, Aisenberg WH, Porras-Paniagua M, Bennett ML, Davtyan H, Spitale RC, Blurton-Jones M, Bennett FC. PMID: 36584406.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    41. Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits. iScience. 2023 Jan 20; 26(1):105732. Reyes-Ortiz AM, Abud EM, Burns MS, Wu J, Hernandez SJ, McClure N, Wang KQ, Schulz CJ, Miramontes R, Lau A, Michael N, Miyoshi E, Van Vactor D, Reidling JC, Blurton-Jones M, Swarup V, Poon WW, Lim RG, Thompson LM. PMID: 36590162; PMCID: PMC9800269.
      View in: PubMed   Mentions: 14  
    42. Microglia states and nomenclature: A field at its crossroads. Neuron. 2022 11 02; 110(21):3458-3483. Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, Boddeke E, Brites D, Brône B, Brown GC, Butovsky O, Carson MJ, Castellano B, Colonna M, Cowley SA, Cunningham C, Davalos D, De Jager PL, de Strooper B, Denes A, Eggen BJL, Eyo U, Galea E, Garel S, Ginhoux F, Glass CK, Gokce O, Gomez-Nicola D, González B, Gordon S, Graeber MB, Greenhalgh AD, Gressens P, Greter M, Gutmann DH, Haass C, Heneka MT, Heppner FL, Hong S, Hume DA, Jung S, Kettenmann H, Kipnis J, Koyama R, Lemke G, Lynch M, Majewska A, Malcangio M, Malm T, Mancuso R, Masuda T, Matteoli M, McColl BW, Miron VE, Molofsky AV, Monje M, Mracsko E, Nadjar A, Neher JJ, Neniskyte U, Neumann H, Noda M, Peng B, Peri F, Perry VH, Popovich PG, Pridans C, Priller J, Prinz M, Ragozzino D, Ransohoff RM, Salter MW, Schaefer A, Schafer DP, Schwartz M, Simons M, Smith CJ, Streit WJ, Tay TL, Tsai LH, Verkhratsky A, von Bernhardi R, Wake H, Wittamer V, Wolf SA, Wu LJ, Wyss-Coray T. PMID: 36327895; PMCID: PMC9999291.
      View in: PubMed   Mentions: 869     Fields:    Translation:Cells
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    98. Neural stem cells improve memory in an inducible mouse model of neuronal loss. J Neurosci. 2007 Oct 31; 27(44):11925-33. Yamasaki TR, Blurton-Jones M, Morrissette DA, Kitazawa M, Oddo S, LaFerla FM. PMID: 17978032; PMCID: PMC6673368.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    99. Origin, migration and fate of newly generated neurons in the adult rodent piriform cortex. Brain Struct Funct. 2007 Sep; 212(2):133-48. Shapiro LA, Ng KL, Kinyamu R, Whitaker-Azmitia P, Geisert EE, Blurton-Jones M, Zhou QY, Ribak CE. PMID: 17764016.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    100. Abeta inhibits the proteasome and enhances amyloid and tau accumulation. Neurobiol Aging. 2008 Nov; 29(11):1607-18. Tseng BP, Green KN, Chan JL, Blurton-Jones M, LaFerla FM. PMID: 17544172; PMCID: PMC2664168.
      View in: PubMed   Mentions: 189     Fields:    Translation:AnimalsCells
    101. Pathways by which Abeta facilitates tau pathology. Curr Alzheimer Res. 2006 Dec; 3(5):437-48. Blurton-Jones M, Laferla FM. PMID: 17168643.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    102. Estradiol-induced modulation of estrogen receptor-beta and GABA within the adult neocortex: a potential transsynaptic mechanism for estrogen modulation of BDNF. J Comp Neurol. 2006 Dec 01; 499(4):603-12. Blurton-Jones M, Tuszynski MH. PMID: 17029253.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    103. Inflammatory changes parallel the early stages of Alzheimer disease. Neurobiol Aging. 2007 Dec; 28(12):1821-33. Parachikova A, Agadjanyan MG, Cribbs DH, Blurton-Jones M, Perreau V, Rogers J, Beach TG, Cotman CW. PMID: 17052803; PMCID: PMC2198930.
      View in: PubMed   Mentions: 113     Fields:    Translation:Humans
    104. A microfluidic culture platform for CNS axonal injury, regeneration and transport. Nat Methods. 2005 Aug; 2(8):599-605. Taylor AM, Blurton-Jones M, Rhee SW, Cribbs DH, Cotman CW, Jeon NL. PMID: 16094385; PMCID: PMC1558906.
      View in: PubMed   Mentions: 550     Fields:    Translation:AnimalsCells
    105. The role of caspase cleavage of tau in Alzheimer disease neuropathology. J Neuropathol Exp Neurol. 2005 Feb; 64(2):104-12. Cotman CW, Poon WW, Rissman RA, Blurton-Jones M. PMID: 15751224.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    106. Caspase-mediated degeneration in Alzheimer's disease. Am J Pathol. 2004 Aug; 165(2):353-5. Cribbs DH, Poon WW, Rissman RA, Blurton-Jones M. PMID: 15277211; PMCID: PMC1618562.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    107. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. J Clin Invest. 2004 Jul; 114(1):121-30. Rissman RA, Poon WW, Blurton-Jones M, Oddo S, Torp R, Vitek MP, LaFerla FM, Rohn TT, Cotman CW. PMID: 15232619; PMCID: PMC437967.
      View in: PubMed   Mentions: 269     Fields:    Translation:HumansAnimalsCells
    108. Estrogen receptor-beta colocalizes extensively with parvalbumin-labeled inhibitory neurons in the cortex, amygdala, basal forebrain, and hippocampal formation of intact and ovariectomized adult rats. J Comp Neurol. 2002 Oct 21; 452(3):276-87. Blurton-Jones M, Tuszynski MH. PMID: 12353223.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    109. An update on estrogen: higher cognitive function, receptor mapping, neurotrophic effects. J Neuropsychiatry Clin Neurosci. 2001; 13(3):313-7. Taber KH, Murphy DD, Blurton-Jones MM, Hurley RA. PMID: 11514636.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    110. Estrogen receptor immunoreactivity in the adult primate brain: neuronal distribution and association with p75, trkA, and choline acetyltransferase. J Comp Neurol. 1999 Mar 22; 405(4):529-42. Blurton-Jones MM, Roberts JA, Tuszynski MH. PMID: 10098943.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
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