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Green, Kim

TitleAssociate Professor and Vice Chair
InstitutionUniversity of California, Irvine
DepartmentNeurobiology & Behavior
Address3208 Biological Sciences III
Zot 4545
CA 92697
Phone(949) 824-3859
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    Collapse Research 
    Collapse Research Activities and Funding
    Microglia are necessary for cortical plaque formation in Alzheimer's disease
    NIH/NIA R01AG056768Jul 1, 2018 - Mar 31, 2023
    Role: Principal Investigator
    Origins, properties, and therapeutic potential of cells that repopulate the micro
    NIH/NINDS R01NS083801Feb 15, 2014 - Jan 31, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Nakazono T, Jun H, Blurton-Jones M, Green K, Igarashi KM. Gamma oscillations in the entorhinal-hippocampal circuit underlying memory and dementia. Neurosci Res. 2018 Apr; 129:40-46. PMID: 29438778.
      View in: PubMed
    2. Hernandez MX, Jiang S, Cole TA, Chu SH, Fonseca MI, Fang MJ, Hohsfield LA, Torres MD, Green K, Wetsel RA, Mortazavi A, Tenner AJ. Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss. Mol Neurodegener. 2017 09 18; 12(1):66. PMID: 28923083.
      View in: PubMed
    3. Caccamo A, Branca C, Piras IS, Ferreira E, Huentelman MJ, Liang WS, Readhead B, Dudley JT, Spangenberg EE, Green K, Belfiore R, Winslow W, Oddo S. Necroptosis activation in Alzheimer's disease. Nat Neurosci. 2017 Sep; 20(9):1236-1246. PMID: 28758999.
      View in: PubMed
    4. Rice RA, Pham J, Lee RJ, Najafi AR, West BL, Green K. Microglial repopulation resolves inflammation and promotes brain recovery after injury. Glia. 2017 06; 65(6):931-944. PMID: 28251674.
      View in: PubMed
    5. Sosnovtsev SV, Sandoval-Jaime C, Parra GI, Tin CM, Jones RW, Soden J, Barnes D, Freeth J, Smith AW, Green K. Identification of Human Junctional Adhesion Molecule 1 as a Functional Receptor for the Hom-1 Calicivirus on Human Cells. MBio. 2017 02 14; 8(1). PMID: 28196955.
      View in: PubMed
    6. Parra GI, Squires RB, Karangwa CK, Johnson JA, Lepore CJ, Sosnovtsev SV, Green K. Static and Evolving Norovirus Genotypes: Implications for Epidemiology and Immunity. PLoS Pathog. 2017 Jan; 13(1):e1006136. PMID: 28103318.
      View in: PubMed
    7. Cotton BT, Hyde JL, Sarvestani ST, Sosnovtsev SV, Green K, White PA, Mackenzie JM. The Norovirus NS3 Protein Is a Dynamic Lipid- and Microtubule-Associated Protein Involved in Viral RNA Replication. J Virol. 2017 Feb 01; 91(3). PMID: 27881660.
      View in: PubMed
    8. Acharya MM, Green K, Allen BD, Najafi AR, Syage A, Minasyan H, Le MT, Kawashita T, Giedzinski E, Parihar VK, West BL, Baulch JE, Limoli CL. Elimination of microglia improves cognitive function following cranial irradiation. Sci Rep. 2016 08 12; 6:31545. PMID: 27516055.
      View in: PubMed
    9. Spangenberg EE, Green K. Inflammation in Alzheimer's disease: Lessons learned from microglia-depletion models. Brain Behav Immun. 2017 Mar; 61:1-11. PMID: 27395435.
      View in: PubMed
    10. Parra GI, Sosnovtsev SV, Abente EJ, Sandoval-Jaime C, Bok K, Dolan MA, Green K. Mapping and modeling of a strain-specific epitope in the Norwalk virus capsid inner shell. Virology. 2016 May; 492:232-41. PMID: 26971245.
      View in: PubMed
    11. Spangenberg EE, Lee RJ, Najafi AR, Rice RA, Elmore MR, Blurton-Jones M, West BL, Green K. Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-ß pathology. Brain. 2016 Apr; 139(Pt 4):1265-81. PMID: 26921617; PMCID: PMC5006229 [Available on 04/01/17].
    12. Dagher NN, Najafi AR, Kayala KM, Elmore MR, White TE, Medeiros R, West BL, Green K. Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice. J Neuroinflammation. 2015 Aug 01; 12:139. PMID: 26232154; PMCID: PMC4522109.
    13. Baglietto-Vargas D, Chen Y, Suh D, Ager RR, Rodriguez-Ortiz CJ, Medeiros R, Myczek K, Green K, Baram TZ, LaFerla FM. Short-term modern life-like stress exacerbates Aß-pathology and synapse loss in 3xTg-AD mice. J Neurochem. 2015 Sep; 134(5):915-26. PMID: 26077803; PMCID: PMC4792118.
    14. Rice RA, Spangenberg EE, Yamate-Morgan H, Lee RJ, Arora RP, Hernandez MX, Tenner AJ, West BL, Green K. Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus. J Neurosci. 2015 Jul 08; 35(27):9977-89. PMID: 26156998; PMCID: PMC4495246.
    15. Elmore MR, Lee RJ, West BL, Green K. Characterizing newly repopulated microglia in the adult mouse: impacts on animal behavior, cell morphology, and neuroinflammation. PLoS One. 2015; 10(4):e0122912. PMID: 25849463.
      View in: PubMed
    16. Lin AJ, Liu G, Castello NA, Yeh JJ, Rahimian R, Lee G, Tsay V, Durkin AJ, Choi B, LaFerla FM, Chen Z, Green K, Tromberg BJ. Optical imaging in an Alzheimer's mouse model reveals amyloid-ß-dependent vascular impairment. Neurophotonics. 2014 Jul; 1(1):011005. PMID: 25133200.
      View in: PubMed
    17. Elmore MR, Najafi AR, Koike MA, Dagher NN, Spangenberg EE, Rice RA, Kitazawa M, Matusow B, Nguyen H, West BL, Green K. Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain. Neuron. 2014 Apr 16; 82(2):380-97. PMID: 24742461; PMCID: PMC4161285.
    18. Castello NA, Nguyen MH, Tran JD, Cheng D, Green K, LaFerla FM. 7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss. PLoS One. 2014; 9(3):e91453. PMID: 24614170; PMCID: PMC3948846.
    19. Chabrier MA, Cheng D, Castello NA, Green K, LaFerla FM. Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease. Neurobiol Dis. 2014 Apr; 64:107-17. PMID: 24440055; PMCID: PMC4072239.
    20. Lin AJ, Castello NA, Lee G, Green K, Durkin AJ, Choi B, LaFerla F, Tromberg BJ. In vivo optical signatures of neuronal death in a mouse model of Alzheimer's disease. Lasers Surg Med. 2014 Jan; 46(1):27-33. PMID: 24284732; PMCID: PMC4001800.
    21. Medeiros R, Castello NA, Cheng D, Kitazawa M, Baglietto-Vargas D, Green K, Esbenshade TA, Bitner RS, Decker MW, LaFerla FM. a7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles. Am J Pathol. 2014 Feb; 184(2):520-9. PMID: 24269557.
      View in: PubMed
    22. Rice RA, Berchtold NC, Cotman CW, Green K. Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production. Neurobiol Aging. 2014 May; 35(5):1002-11. PMID: 24268883; PMCID: PMC3939046.
    23. Baglietto-Vargas D, Kitazawa M, Le EJ, Estrada-Hernandez T, Rodriguez-Ortiz CJ, Medeiros R, Green K, LaFerla FM. Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition. Neurobiol Dis. 2014 Feb; 62:407-15. PMID: 24176788.
      View in: PubMed
    24. Parra GI, Azure J, Fischer R, Bok K, Sandoval-Jaime C, Sosnovtsev SV, Sander P, Green K. Identification of a Broadly Cross-Reactive Epitope in the Inner Shell of the Norovirus Capsid. PLoS One. 2013; 8(6):e67592. PMID: 23805319; PMCID: PMC3689733.
    25. Rackoff LA, Bok K, Green K, Kapikian AZ. Epidemiology and evolution of rotaviruses and noroviruses from an archival WHO Global Study in Children (1976-79) with implications for vaccine design. PLoS One. 2013; 8(3):e59394. PMID: 23536875; PMCID: PMC3607611.
    26. Baglietto-Vargas D, Medeiros R, Martinez-Coria H, LaFerla FM, Green K. Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology. Biol Psychiatry. 2013 Sep 01; 74(5):357-66. PMID: 23312564; PMCID: PMC3633722.
    27. LaFerla FM, Green K. Animal models of Alzheimer disease. Cold Spring Harb Perspect Med. 2012 Nov 01; 2(11). PMID: 23002015; PMCID: PMC3543097.
    28. Neely Kayala KM, Dickinson GD, Minassian A, Walls KC, Green K, Laferla FM. Presenilin-null cells have altered two-pore calcium channel expression and lysosomal calcium: implications for lysosomal function. Brain Res. 2012 Dec 13; 1489:8-16. PMID: 23103503; PMCID: PMC3516298.
    29. Koike MA, Lin AJ, Pham J, Nguyen E, Yeh JJ, Rahimian R, Tromberg BJ, Choi B, Green K, LaFerla FM. APP knockout mice experience acute mortality as the result of ischemia. PLoS One. 2012; 7(8):e42665. PMID: 22912719; PMCID: PMC3415410.
    30. Castello NA, Green K, LaFerla FM. Genetic knockdown of brain-derived neurotrophic factor in 3xTg-AD mice does not alter Aß or tau pathology. PLoS One. 2012; 7(8):e39566. PMID: 22870188; PMCID: PMC3411687.
    31. Walls KC, Coskun P, Gallegos-Perez JL, Zadourian N, Freude K, Rasool S, Blurton-Jones M, Green K, LaFerla FM. Swedish Alzheimer mutation induces mitochondrial dysfunction mediated by HSP60 mislocalization of amyloid precursor protein (APP) and beta-amyloid. J Biol Chem. 2012 Aug 31; 287(36):30317-27. PMID: 22753410; PMCID: PMC3436283.
    32. Medeiros R, Kitazawa M, Chabrier MA, Cheng D, Baglietto-Vargas D, Kling A, Moeller A, Green K, LaFerla FM. Calpain inhibitor A-705253 mitigates Alzheimer's disease-like pathology and cognitive decline in aged 3xTgAD mice. Am J Pathol. 2012 Aug; 181(2):616-25. PMID: 22688056.
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    33. Parra GI, Abente EJ, Sandoval-Jaime C, Sosnovtsev SV, Bok K, Green K. Multiple antigenic sites are involved in blocking the interaction of GII.4 norovirus capsid with ABH histo-blood group antigens. J Virol. 2012 Jul; 86(13):7414-26. PMID: 22532688; PMCID: PMC3416322.
    34. Hwang S, Maloney NS, Bruinsma MW, Goel G, Duan E, Zhang L, Shrestha B, Diamond MS, Dani A, Sosnovtsev SV, Green K, Lopez-Otin C, Xavier RJ, Thackray LB, Virgin HW. Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma. Cell Host Microbe. 2012 Apr 19; 11(4):397-409. PMID: 22520467; PMCID: PMC3348177.
    35. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, Garcia-Manero G, Garcia-Marcos M, Garmyn M, Gartel AL, Gatti E, Gautel M, Gawriluk TR, Gegg ME, Geng J, Germain M, Gestwicki JE, Gewirtz DA, Ghavami S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. PMID: 22966490.
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    36. Barron EL, Sosnovtsev SV, Bok K, Prikhodko V, Sandoval-Jaime C, Rhodes CR, Hasenkrug K, Carmody AB, Ward JM, Perdue K, Green K. Diversity of murine norovirus strains isolated from asymptomatic mice of different genetic backgrounds within a single U.S. research institute. PLoS One. 2011; 6(6):e21435. PMID: 21738664.
      View in: PubMed
    37. Neely KM, Green K. Presenilins mediate efficient proteolysis via the autophagosome-lysosome system. Autophagy. 2011 Jun; 7(6):664-5. PMID: 21460614.
      View in: PubMed
    38. Green K, Khashwji H, Estrada T, Laferla FM. ST101 induces a novel 17 kDa APP cleavage that precludes Aß generation in vivo. Ann Neurol. 2011 May; 69(5):831-44. PMID: 21416488.
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    39. Neely KM, Green K, LaFerla FM. Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a ?-secretase-independent manner. J Neurosci. 2011 Feb 23; 31(8):2781-91. PMID: 21414900; PMCID: PMC3064964.
    40. Lin AJ, Koike MA, Green K, Kim JG, Mazhar A, Rice TB, LaFerla FM, Tromberg BJ. Spatial frequency domain imaging of intrinsic optical property contrast in a mouse model of Alzheimer's disease. Ann Biomed Eng. 2011 Apr; 39(4):1349-57. PMID: 21331663; PMCID: PMC3069335.
    41. Parachikova A, Green K, Hendrix C, LaFerla FM. Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease. PLoS One. 2010 Nov 17; 5(11):e14015. PMID: 21103342; PMCID: PMC2984445.
    42. Koike MA, Green K, Blurton-Jones M, Laferla FM. Oligemic hypoperfusion differentially affects tau and amyloid-{beta}. Am J Pathol. 2010 Jul; 177(1):300-10. PMID: 20472896; PMCID: PMC2893673.
    43. Parachikova A, Vasilevko V, Cribbs DH, LaFerla FM, Green K. Reductions in amyloid-beta-derived neuroinflammation, with minocycline, restore cognition but do not significantly affect tau hyperphosphorylation. J Alzheimers Dis. 2010; 21(2):527-42. PMID: 20555131; PMCID: PMC4085054.
    44. Martinez-Coria H, Green K, Billings LM, Kitazawa M, Albrecht M, Rammes G, Parsons CG, Gupta S, Banerjee P, LaFerla FM. Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice. Am J Pathol. 2010 Feb; 176(2):870-80. PMID: 20042680; PMCID: PMC2808092.
    45. Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, Zeitlin SO, Finkbeiner S, Green K, LaFerla FM, Bates G, Huang L, Patterson PH, Lo DC, Cuervo AM, Marsh JL, Steffan JS. IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. J Cell Biol. 2009 Dec 28; 187(7):1083-99. PMID: 20026656; PMCID: PMC2806289.
    46. Aiken CT, Steffan JS, Guerrero CM, Khashwji H, Lukacsovich T, Simmons D, Purcell JM, Menhaji K, Zhu YZ, Green K, Laferla F, Huang L, Thompson LM, Marsh JL. Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity. J Biol Chem. 2009 Oct 23; 284(43):29427-36. PMID: 19710014; PMCID: PMC2785575.
    47. Green K. Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology. J Cell Mol Med. 2009 Sep; 13(9A):2787-99. PMID: 19650832; PMCID: PMC4498936.
    48. Blurton-Jones M, Kitazawa M, Martinez-Coria H, Castello NA, Müller FJ, Loring JF, Yamasaki TR, Poon WW, Green K, LaFerla FM. Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13594-9. PMID: 19633196.
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    49. Green K, Steffan JS, Martinez-Coria H, Sun X, Schreiber SS, Thompson LM, LaFerla FM. Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau. J Neurosci. 2008 Nov 05; 28(45):11500-10. PMID: 18987186; PMCID: PMC2617713.
    50. Morrissette DA, Parachikova A, Green K, LaFerla FM. Relevance of transgenic mouse models to human Alzheimer disease. J Biol Chem. 2009 Mar 06; 284(10):6033-7. PMID: 18948253.
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    51. Green K, LaFerla FM. Linking calcium to Abeta and Alzheimer's disease. Neuron. 2008 Jul 31; 59(2):190-4. PMID: 18667147.
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    52. Green K, Demuro A, Akbari Y, Hitt BD, Smith IF, Parker I, LaFerla FM. SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. J Cell Biol. 2008 Jun 30; 181(7):1107-16. PMID: 18591429; PMCID: PMC2442205.
    53. LaFerla FM, Green K, Oddo S. Intracellular amyloid-beta in Alzheimer's disease. Nat Rev Neurosci. 2007 Jul; 8(7):499-509. PMID: 17551515.
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    54. Clinton LK, Billings LM, Green K, Caccamo A, Ngo J, Oddo S, McGaugh JL, LaFerla FM. Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice. Neurobiol Dis. 2007 Oct; 28(1):76-82. PMID: 17659878; PMCID: PMC2756084.
    55. Tseng BP, Green K, Chan JL, Blurton-Jones M, LaFerla FM. Abeta inhibits the proteasome and enhances amyloid and tau accumulation. Neurobiol Aging. 2008 Nov; 29(11):1607-18. PMID: 17544172; PMCID: PMC2664168.
    56. Green K, Martinez-Coria H, Khashwji H, Hall EB, Yurko-Mauro KA, Ellis L, LaFerla FM. Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels. J Neurosci. 2007 Apr 18; 27(16):4385-95. PMID: 17442823.
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    57. Billings LM, Green K, McGaugh JL, LaFerla FM. Learning decreases A beta*56 and tau pathology and ameliorates behavioral decline in 3xTg-AD mice. J Neurosci. 2007 Jan 24; 27(4):751-61. PMID: 17251414.
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    58. Green K, Billings LM, Roozendaal B, McGaugh JL, LaFerla FM. Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease. J Neurosci. 2006 Aug 30; 26(35):9047-56. PMID: 16943563.
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    59. Chang KO, Sosnovtsev SV, Belliot G, King AD, Green K. Stable expression of a Norwalk virus RNA replicon in a human hepatoma cell line. Virology. 2006 Sep 30; 353(2):463-73. PMID: 16843517.
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    60. Kitazawa M, Green K, Caccamo A, LaFerla FM. Genetically augmenting Abeta42 levels in skeletal muscle exacerbates inclusion body myositis-like pathology and motor deficits in transgenic mice. Am J Pathol. 2006 Jun; 168(6):1986-97. PMID: 16723713; PMCID: PMC1606633.
    61. Caccamo A, Oddo S, Billings LM, Green K, Martinez-Coria H, Fisher A, LaFerla FM. M1 receptors play a central role in modulating AD-like pathology in transgenic mice. Neuron. 2006 Mar 02; 49(5):671-82. PMID: 16504943.
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    62. Ward JM, Wobus CE, Thackray LB, Erexson CR, Faucette LJ, Belliot G, Barron EL, Sosnovtsev SV, Green K. Pathology of immunodeficient mice with naturally occurring murine norovirus infection. Toxicol Pathol. 2006; 34(6):708-15. PMID: 17074739.
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    63. Oddo S, Caccamo A, Smith IF, Green K, LaFerla FM. A dynamic relationship between intracellular and extracellular pools of Abeta. Am J Pathol. 2006 Jan; 168(1):184-94. PMID: 16400022; PMCID: PMC1592652.
    64. Kitazawa M, Oddo S, Yamasaki TR, Green K, LaFerla FM. Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. J Neurosci. 2005 Sep 28; 25(39):8843-53. PMID: 16192374.
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    65. Smith IF, Green K, LaFerla FM. Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals. Cell Calcium. 2005 Sep-Oct; 38(3-4):427-37. PMID: 16125228.
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    66. Smith IF, Hitt B, Green K, Oddo S, LaFerla FM. Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease. J Neurochem. 2005 Sep; 94(6):1711-8. PMID: 16156741.
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    67. Billings LM, Oddo S, Green K, McGaugh JL, LaFerla FM. Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron. 2005 Mar 03; 45(5):675-88. PMID: 15748844.
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    68. Oddo S, Caccamo A, Green K, Liang K, Tran L, Chen Y, Leslie FM, LaFerla FM. Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):3046-51. PMID: 15705720; PMCID: PMC549455.
    69. Wobus CE, Karst SM, Thackray LB, Chang KO, Sosnovtsev SV, Belliot G, Krug A, Mackenzie JM, Green K, Virgin HW. Replication of Norovirus in cell culture reveals a tropism for dendritic cells and macrophages. PLoS Biol. 2004 Dec; 2(12):e432. PMID: 15562321; PMCID: PMC532393.
    70. Webster NJ, Green K, Settle VJ, Peers C, Vaughan PF. Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways. Brain Res Mol Brain Res. 2004 Nov 04; 130(1-2):161-9. PMID: 15519686.
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