Kim Green

Title(s)Associate Professor and Vice Chair, Neurobiology & Behavior
SchoolSchool of Biological Sciences
Address3208 Biological Sciences III
Zot 4545
Irvine CA 92697
Phone(949) 824-3859
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    Collapse Research 
    Collapse Research Activities and Funding
    The lipid amidase NAAA as a therapeutic target for Alzheimer's disease
    NIH RF1AG065329Sep 15, 2020 - Aug 31, 2024
    Role: Co-Principal Investigator
    Microglia are necessary for cortical plaque formation in Alzheimer's disease
    NIH/NIA R01AG056768Jul 1, 2018 - Mar 31, 2023
    Role: Principal Investigator
    Microglia are necessary for cortical plaque formation in Alzheimer's disease
    NIH RF1AG056768Jul 1, 2018 - Mar 31, 2023
    Role: Principal Investigator
    Origins, properties, and therapeutic potential of cells that repopulate the microglia-depleted adult brain
    NIH R01NS083801Feb 15, 2014 - Jan 31, 2024
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sex-specific associations between AD genotype and the microbiome of human amyloid beta knock-in (hAβ-KI) mice. Alzheimers Dement. 2024 Apr 04. Dunham SJB, Avelar-Barragan J, Rothman JA, Adams ED, Faraci G, Forner S, Kawauchi S, Tenner AJ, Green KN, LaFerla FM, MacGregor GR, Mapstone M, Whiteson KL. PMID: 38572865.
      View in: PubMed   Mentions:    Fields:    
    2. The Abca7V1613M variant reduces Aβ generation, plaque load, and neuronal damage. Alzheimers Dement. 2024 Mar 20. Butler CA, Mendoza Arvilla A, Milinkeviciute G, Da Cunha C, Kawauchi S, Rezaie N, Liang HY, Javonillo D, Thach A, Wang S, Collins S, Walker A, Shi KX, Neumann J, Gomez-Arboledas A, Henningfield CM, Hohsfield LA, Mapstone M, Tenner AJ, LaFerla FM, Mortazavi A, MacGregor GR, Green KN. PMID: 38506634.
      View in: PubMed   Mentions:    Fields:    
    3. BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease. Alzheimers Dement. 2024 Mar 09. Garcia-Agudo LF, Shi Z, Smith IF, Kramár EA, Tran K, Kawauchi S, Wang S, Collins S, Walker A, Shi KX, Neumann J, Liang HY, Da Cunha C, Milinkeviciute G, Morabito S, Miyoshi E, Rezaie N, Gomez-Arboledas A, Arvilla AM, Ghaemi DI, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, Swarup V, MacGregor GR, Green KN. PMID: 38460121.
      View in: PubMed   Mentions:    Fields:    
    4. Genetic diversity promotes resilience in a mouse model of Alzheimer's disease. Alzheimers Dement. 2024 Mar 01. Soni N, Hohsfield LA, Tran KM, Kawauchi S, Walker A, Javonillo D, Phan J, Matheos D, Da Cunha C, Uyar A, Milinkeviciute G, Gomez-Arboledas A, Tran K, Kaczorowski CC, Wood MA, Tenner AJ, LaFerla FM, Carter GW, Mortazavi A, Swarup V, MacGregor GR, Green KN. PMID: 38426371.
      View in: PubMed   Mentions:    Fields:    
    5. Single cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer's risk gene mutation. Res Sq. 2023 Dec 07. Johnston K, Berackey BB, Tran KM, Gelber A, Yu Z, MacGregor G, Mukamel EA, Tan Z, Green K, Xu X. PMID: 38106071; PMCID: PMC10723554.
      View in: PubMed   Mentions:
    6. Microglia influence immune responses and restrict neurologic disease in response to central nervous system infection by a neurotropic murine coronavirus. Front Cell Neurosci. 2023; 17:1291255. Syage A, Pachow C, Cheng Y, Mangale V, Green KN, Lane TE. PMID: 38099152; PMCID: PMC10719854.
      View in: PubMed   Mentions:
    7. Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis. Nat Cell Biol. 2023 Dec; 25(12):1848-1859. Evans KT, Blake K, Longworth A, Coburn MA, Insua-Rodríguez J, McMullen TP, Nguyen QH, Ma D, Lev T, Hernandez GA, Oganyan AK, Orujyan D, Edwards RA, Pridans C, Green KN, Villalta SA, Blurton-Jones M, Lawson DA. PMID: 37957324.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. COVID-19 and the impact on Alzheimer's disease pathology. J Neurochem. 2023 Oct 18. Furman S, Green K, Lane TE. PMID: 37850241.
      View in: PubMed   Mentions: 1     Fields:    
    9. A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity. Nat Commun. 2023 10 16; 14(1):6516. Salmen W, Hu L, Bok M, Chaimongkol N, Ettayebi K, Sosnovtsev SV, Soni K, Ayyar BV, Shanker S, Neill FH, Sankaran B, Atmar RL, Estes MK, Green KY, Parreño V, Prasad BVV. PMID: 37845211; PMCID: PMC10579229.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    10. Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's Disease. bioRxiv. 2023 Jul 26. Miyoshi E, Morabito S, Henningfield CM, Rahimzadeh N, Kiani Shabestari S, Das S, Michael N, Reese F, Shi Z, Cao Z, Scarfone V, Arreola MA, Lu J, Wright S, Silva J, Leavy K, Lott IT, Doran E, Yong WH, Shahin S, Perez-Rosendahl M, Head E, Green KN, Swarup V. PMID: 37546983; PMCID: PMC10402031.
      View in: PubMed   Mentions:
    11. Ablation of microglia following infection of the central nervous system with a neurotropic murine coronavirus infection leads to increased demyelination and impaired remyelination. J Neuroimmunol. 2023 08 15; 381:578133. Cheng Y, Javonillo DI, Pachow C, Scarfone VM, Fernandez K, Walsh CM, Green KN, Lane TE. PMID: 37352687.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    12. Clusterin/apolipoprotein J, its isoforms and Alzheimer's disease. Front Aging Neurosci. 2023; 15:1167886. Milinkeviciute G, Green KN. PMID: 37122381; PMCID: PMC10133478.
      View in: PubMed   Mentions: 1  
    13. A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques. Mol Neurodegener. 2023 02 17; 18(1):12. Tran KM, Kawauchi S, Kramár EA, Rezaie N, Liang HY, Sakr JS, Gomez-Arboledas A, Arreola MA, Cunha CD, Phan J, Wang S, Collins S, Walker A, Shi KX, Neumann J, Filimban G, Shi Z, Milinkeviciute G, Javonillo DI, Tran K, Gantuz M, Forner S, Swarup V, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, MacGregor GR, Green KN. PMID: 36803190; PMCID: PMC9938579.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    14. Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer's disease. Neurobiol Dis. 2023 01; 176:105939. Zhang H, Chen L, Johnston KG, Crapser J, Green KN, Ha NM, Tenner AJ, Holmes TC, Nitz DA, Xu X. PMID: 36462718; PMCID: PMC10187684.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    15. Targeting NAAA counters dopamine neuron loss and symptom progression in mouse models of parkinsonism. Pharmacol Res. 2022 08; 182:106338. Palese F, Pontis S, Realini N, Torrens A, Ahmed F, Assogna F, Pellicano C, Bossù P, Spalletta G, Green K, Piomelli D. PMID: 35781057; PMCID: PMC9733952.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    16. Frequent Low-Dose Δ9-Tetrahydrocannabinol in Adolescence Disrupts Microglia Homeostasis and Disables Responses to Microbial Infection and Social Stress in Young Adulthood. Biol Psychiatry. 2022 12 01; 92(11):845-860. Lee HL, Jung KM, Fotio Y, Squire E, Palese F, Lin L, Torrens A, Ahmed F, Mabou Tagne A, Ramirez J, Su S, Wong CR, Jung DH, Scarfone VM, Nguyen PU, Wood M, Green K, Piomelli D. PMID: 35750512; PMCID: PMC10629396.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    17. Commentary: How Do Microglia Regulate Neural Circuit Connectivity and Activity in the Adult Brain? Neurosci Insights. 2022; 17:26331055211071124. Liu YJ, Green KN, Holmes TC, Xu X. PMID: 35098130; PMCID: PMC8796061.
      View in: PubMed   Mentions:
    18. Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease. Front Neurosci. 2021; 15:785276. Javonillo DI, Tran KM, Phan J, Hingco E, Kramár EA, da Cunha C, Forner S, Kawauchi S, Milinkeviciute G, Gomez-Arboledas A, Neumann J, Banh CE, Huynh M, Matheos DP, Rezaie N, Alcantara JA, Mortazavi A, Wood MA, Tenner AJ, MacGregor GR, Green KN, LaFerla FM. PMID: 35140584; PMCID: PMC8818877.
      View in: PubMed   Mentions: 37  
    19. MAC2 is a long-lasting marker of peripheral cell infiltrates into the mouse CNS after bone marrow transplantation and coronavirus infection. Glia. 2022 05; 70(5):875-891. Hohsfield LA, Tsourmas KI, Ghorbanian Y, Syage AR, Jin Kim S, Cheng Y, Furman S, Inlay MA, Lane TE, Green KN. PMID: 35025109; PMCID: PMC8930563.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    20. Cortical diurnal rhythms remain intact with microglial depletion. Sci Rep. 2022 01 07; 12(1):114. Barahona RA, Morabito S, Swarup V, Green KN. PMID: 34997092; PMCID: PMC8742049.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    21. Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice. J Virol. 2022 02 23; 96(4):e0196921. Olivarria GM, Cheng Y, Furman S, Pachow C, Hohsfield LA, Smith-Geater C, Miramontes R, Wu J, Burns MS, Tsourmas KI, Stocksdale J, Manlapaz C, Yong WH, Teijaro J, Edwards R, Green KN, Thompson LM, Lane TE. PMID: 34935438; PMCID: PMC8865461.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    22. Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic mice. bioRxiv. 2021 Nov 17. Olivarria GM, Cheng Y, Furman S, Pachow C, Hohsfield LA, Smith-Geater C, Miramontes R, Wu J, Burns MS, Tsourmas KI, Stocksdale J, Manlapaz C, Yong WH, Teijaro J, Edwards R, Green KN, Thompson LM, Lane TE. PMID: 34816260; PMCID: PMC8609895.
      View in: PubMed   Mentions:
    23. Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease. Sci Data. 2021 10 15; 8(1):270. Forner S, Kawauchi S, Balderrama-Gutierrez G, Kramár EA, Matheos DP, Phan J, Javonillo DI, Tran KM, Hingco E, da Cunha C, Rezaie N, Alcantara JA, Baglietto-Vargas D, Jansen C, Neumann J, Wood MA, MacGregor GR, Mortazavi A, Tenner AJ, LaFerla FM, Green KN. PMID: 34654824; PMCID: PMC8519958.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    24. Microglia-specific ApoE knock-out does not alter Alzheimer's disease plaque pathogenesis or gene expression. Glia. 2022 02; 70(2):287-302. Henningfield CM, Arreola MA, Soni N, Spangenberg EE, Green KN. PMID: 34643971; PMCID: PMC9308171.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    25. Microglial dyshomeostasis drives perineuronal net and synaptic loss in a CSF1R+/- mouse model of ALSP, which can be rescued via CSF1R inhibitors. Sci Adv. 2021 Aug; 7(35). Arreola MA, Soni N, Crapser JD, Hohsfield LA, Elmore MRP, Matheos DP, Wood MA, Swarup V, Mortazavi A, Green KN. PMID: 34433559; PMCID: PMC8386924.
      View in: PubMed   Mentions: 18     Fields:    
    26. Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave. Elife. 2021 08 23; 10. Hohsfield LA, Najafi AR, Ghorbanian Y, Soni N, Crapser J, Figueroa Velez DX, Jiang S, Royer SE, Kim SJ, Henningfield CM, Anderson A, Gandhi SP, Mortazavi A, Inlay MA, Green KN. PMID: 34423781; PMCID: PMC8425950.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    27. Microglia as hackers of the matrix: sculpting synapses and the extracellular space. Cell Mol Immunol. 2021 11; 18(11):2472-2488. Crapser JD, Arreola MA, Tsourmas KI, Green KN. PMID: 34413489; PMCID: PMC8546068.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    28. Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology. Nat Commun. 2021 04 23; 12(1):2421. Baglietto-Vargas D, Forner S, Cai L, Martini AC, Trujillo-Estrada L, Swarup V, Nguyen MMT, Do Huynh K, Javonillo DI, Tran KM, Phan J, Jiang S, Kramár EA, Nuñez-Diaz C, Balderrama-Gutierrez G, Garcia F, Childs J, Rodriguez-Ortiz CJ, Garcia-Leon JA, Kitazawa M, Shahnawaz M, Matheos DP, Ma X, Da Cunha C, Walls KC, Ager RR, Soto C, Gutierrez A, Moreno-Gonzalez I, Mortazavi A, Tenner AJ, MacGregor GR, Wood M, Green KN, LaFerla FM. PMID: 33893290; PMCID: PMC8065162.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    29. On the utility of CSF1R inhibitors. Proc Natl Acad Sci U S A. 2021 01 26; 118(4). Green KN, Hume DA. PMID: 33446486; PMCID: PMC7848745.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    30. Microglia Elimination Increases Neural Circuit Connectivity and Activity in Adult Mouse Cortex. J Neurosci. 2021 02 10; 41(6):1274-1287. Liu YJ, Spangenberg EE, Tang B, Holmes TC, Green KN, Xu X. PMID: 33380470; PMCID: PMC7888230.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    31. Model organism development and evaluation for late-onset Alzheimer's disease: MODEL-AD. Alzheimers Dement (N Y). 2020; 6(1):e12110. Oblak AL, Forner S, Territo PR, Sasner M, Carter GW, Howell GR, Sukoff-Rizzo SJ, Logsdon BA, Mangravite LM, Mortazavi A, Baglietto-Vargas D, Green KN, MacGregor GR, Wood MA, Tenner AJ, LaFerla FM, Lamb BT, and The MODEL-AD, Consortium. PMID: 33283040; PMCID: PMC7683958.
      View in: PubMed   Mentions: 41  
    32. Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNS. J Neuroinflammation. 2020 Sep 20; 17(1):279. Hohsfield LA, Najafi AR, Ghorbanian Y, Soni N, Hingco EE, Kim SJ, Jue AD, Swarup V, Inlay MA, Green KN. PMID: 32951604; PMCID: PMC7504855.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    33. To Kill a Microglia: A Case for CSF1R Inhibitors. Trends Immunol. 2020 09; 41(9):771-784. Green KN, Crapser JD, Hohsfield LA. PMID: 32792173; PMCID: PMC7484341.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    34. Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain. EBioMedicine. 2020 Aug; 58:102919. Crapser JD, Spangenberg EE, Barahona RA, Arreola MA, Hohsfield LA, Green KN. PMID: 32745992; PMCID: PMC7399129.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimalsCells
    35. Aging and Progression of Beta-Amyloid Pathology in Alzheimer's Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression. Antioxidants (Basel). 2020 Jul 21; 9(7). Fernández-Mendívil C, Arreola MA, Hohsfield LA, Green KN, Lopez MG. PMID: 32708329; PMCID: PMC7402118.
      View in: PubMed   Mentions: 11  
    36. Human norovirus targets enteroendocrine epithelial cells in the small intestine. Nat Commun. 2020 06 02; 11(1):2759. Green KY, Kaufman SS, Nagata BM, Chaimongkol N, Kim DY, Levenson EA, Tin CM, Yardley AB, Johnson JA, Barletta ABF, Khan KM, Yazigi NA, Subramanian S, Moturi SR, Fishbein TM, Moore IN, Sosnovtsev SV. PMID: 32488028; PMCID: PMC7265440.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    37. Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system. Glia. 2020 11; 68(11):2345-2360. Mangale V, Syage AR, Ekiz HA, Skinner DD, Cheng Y, Stone CL, Brown RM, O'Connell RM, Green KN, Lane TE. PMID: 32449994; PMCID: PMC7280614.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    38. Retraction for Kim et al., "Newcastle Disease Virus Vector Producing Human Norovirus-Like Particles Induces Serum, Cellular, and Mucosal Immune Responses in Mice". J Virol. 2020 02 28; 94(6). Kim SH, Chen S, Jiang X, Green KY, Samal SK. PMID: 32111812; PMCID: PMC7158728.
      View in: PubMed   Mentions:    Fields:    
    39. Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease. Brain. 2020 01 01; 143(1):266-288. Crapser JD, Ochaba J, Soni N, Reidling JC, Thompson LM, Green KN. PMID: 31848580; PMCID: PMC6935750.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    40. Microglia Regulate Pruning of Specialized Synapses in the Auditory Brainstem. Front Neural Circuits. 2019; 13:55. Milinkeviciute G, Henningfield CM, Muniak MA, Chokr SM, Green KN, Cramer KS. PMID: 31555101; PMCID: PMC6722190.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    41. Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model. Nat Commun. 2019 08 21; 10(1):3758. Spangenberg E, Severson PL, Hohsfield LA, Crapser J, Zhang J, Burton EA, Zhang Y, Spevak W, Lin J, Phan NY, Habets G, Rymar A, Tsang G, Walters J, Nespi M, Singh P, Broome S, Ibrahim P, Zhang C, Bollag G, West BL, Green KN. PMID: 31434879; PMCID: PMC6704256.
      View in: PubMed   Mentions: 297     Fields:    Translation:HumansAnimalsCells
    42. A limited capacity for microglial repopulation in the adult brain. Glia. 2018 11; 66(11):2385-2396. Najafi AR, Crapser J, Jiang S, Ng W, Mortazavi A, West BL, Green KN. PMID: 30370589; PMCID: PMC6269202.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    43. Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice. Aging Cell. 2018 Dec; 17(6):e12832. Elmore MRP, Hohsfield LA, Kramár EA, Soreq L, Lee RJ, Pham ST, Najafi AR, Spangenberg EE, Wood MA, West BL, Green KN. PMID: 30276955; PMCID: PMC6260908.
      View in: PubMed   Mentions: 135     Fields:    Translation:AnimalsCells
    44. Gamma oscillations in the entorhinal-hippocampal circuit underlying memory and dementia. Neurosci Res. 2018 Apr; 129:40-46. Nakazono T, Jun H, Blurton-Jones M, Green KN, Igarashi KM. PMID: 29438778; PMCID: PMC7059556.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    45. Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss. Mol Neurodegener. 2017 09 18; 12(1):66. Hernandez MX, Jiang S, Cole TA, Chu SH, Fonseca MI, Fang MJ, Hohsfield LA, Torres MD, Green KN, Wetsel RA, Mortazavi A, Tenner AJ. PMID: 28923083; PMCID: PMC5604420.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    46. Necroptosis activation in Alzheimer's disease. Nat Neurosci. 2017 Sep; 20(9):1236-1246. Caccamo A, Branca C, Piras IS, Ferreira E, Huentelman MJ, Liang WS, Readhead B, Dudley JT, Spangenberg EE, Green KN, Belfiore R, Winslow W, Oddo S. PMID: 28758999.
      View in: PubMed   Mentions: 184     Fields:    Translation:HumansAnimalsCells
    47. Human Sera Collected between 1979 and 2010 Possess Blocking-Antibody Titers to Pandemic GII.4 Noroviruses Isolated over Three Decades. J Virol. 2017 07 15; 91(14). Sharma S, Carlsson B, Czakó R, Vene S, Haglund M, Ludvigsson J, Larson G, Hammarström L, Sosnovtsev SV, Atmar RL, Green KY, Estes MK, Svensson L. PMID: 28468886; PMCID: PMC5487561.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    48. Microglial repopulation resolves inflammation and promotes brain recovery after injury. Glia. 2017 06; 65(6):931-944. Rice RA, Pham J, Lee RJ, Najafi AR, West BL, Green KN. PMID: 28251674; PMCID: PMC5395311.
      View in: PubMed   Mentions: 110     Fields:    Translation:AnimalsCells
    49. Identification of Human Junctional Adhesion Molecule 1 as a Functional Receptor for the Hom-1 Calicivirus on Human Cells. mBio. 2017 02 14; 8(1). Sosnovtsev SV, Sandoval-Jaime C, Parra GI, Tin CM, Jones RW, Soden J, Barnes D, Freeth J, Smith AW, Green KY. PMID: 28196955; PMCID: PMC5312078.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    50. Static and Evolving Norovirus Genotypes: Implications for Epidemiology and Immunity. PLoS Pathog. 2017 01; 13(1):e1006136. Parra GI, Squires RB, Karangwa CK, Johnson JA, Lepore CJ, Sosnovtsev SV, Green KY. PMID: 28103318; PMCID: PMC5283768.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansCells
    51. The Norovirus NS3 Protein Is a Dynamic Lipid- and Microtubule-Associated Protein Involved in Viral RNA Replication. J Virol. 2017 Feb 01; 91(3). Cotton BT, Hyde JL, Sarvestani ST, Sosnovtsev SV, Green KY, White PA, Mackenzie JM. PMID: 27881660; PMCID: PMC5244318.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    52. Elimination of microglia improves cognitive function following cranial irradiation. Sci Rep. 2016 08 12; 6:31545. Acharya MM, Green KN, Allen BD, Najafi AR, Syage A, Minasyan H, Le MT, Kawashita T, Giedzinski E, Parihar VK, West BL, Baulch JE, Limoli CL. PMID: 27516055; PMCID: PMC4981848.
      View in: PubMed   Mentions: 116     Fields:    Translation:AnimalsCells
    53. Inflammation in Alzheimer's disease: Lessons learned from microglia-depletion models. Brain Behav Immun. 2017 Mar; 61:1-11. Spangenberg EE, Green KN. PMID: 27395435; PMCID: PMC5218993.
      View in: PubMed   Mentions: 136     Fields:    Translation:AnimalsCells
    54. Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology. Brain. 2016 Apr; 139(Pt 4):1265-81. Spangenberg EE, Lee RJ, Najafi AR, Rice RA, Elmore MR, Blurton-Jones M, West BL, Green KN. PMID: 26921617; PMCID: PMC5006229.
      View in: PubMed   Mentions: 314     Fields:    Translation:AnimalsCells
    55. Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice. J Neuroinflammation. 2015 Aug 01; 12:139. Dagher NN, Najafi AR, Kayala KM, Elmore MR, White TE, Medeiros R, West BL, Green KN. PMID: 26232154; PMCID: PMC4522109.
      View in: PubMed   Mentions: 238     Fields:    Translation:HumansAnimalsCells
    56. Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice. J Neurochem. 2015 Sep; 134(5):915-26. Baglietto-Vargas D, Chen Y, Suh D, Ager RR, Rodriguez-Ortiz CJ, Medeiros R, Myczek K, Green KN, Baram TZ, LaFerla FM. PMID: 26077803; PMCID: PMC4792118.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    57. Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus. J Neurosci. 2015 Jul 08; 35(27):9977-89. Rice RA, Spangenberg EE, Yamate-Morgan H, Lee RJ, Arora RP, Hernandez MX, Tenner AJ, West BL, Green KN. PMID: 26156998; PMCID: PMC4495246.
      View in: PubMed   Mentions: 131     Fields:    Translation:AnimalsCells
    58. Characterizing newly repopulated microglia in the adult mouse: impacts on animal behavior, cell morphology, and neuroinflammation. PLoS One. 2015; 10(4):e0122912. Elmore MR, Lee RJ, West BL, Green KN. PMID: 25849463; PMCID: PMC4388515.
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    61. Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain. Neuron. 2014 Apr 16; 82(2):380-97. Elmore MR, Najafi AR, Koike MA, Dagher NN, Spangenberg EE, Rice RA, Kitazawa M, Matusow B, Nguyen H, West BL, Green KN. PMID: 24742461; PMCID: PMC4161285.
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    62. 7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss. PLoS One. 2014; 9(3):e91453. Castello NA, Nguyen MH, Tran JD, Cheng D, Green KN, LaFerla FM. PMID: 24614170; PMCID: PMC3948846.
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    63. Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease. Neurobiol Dis. 2014 Apr; 64:107-17. Chabrier MA, Cheng D, Castello NA, Green KN, LaFerla FM. PMID: 24440055; PMCID: PMC4072239.
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    64. In vivo optical signatures of neuronal death in a mouse model of Alzheimer's disease. Lasers Surg Med. 2014 Jan; 46(1):27-33. Lin AJ, Castello NA, Lee G, Green KN, Durkin AJ, Choi B, LaFerla F, Tromberg BJ. PMID: 24284732; PMCID: PMC4001800.
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    65. Identification and characterization of antibody-binding epitopes on the norovirus GII.3 capsid. J Virol. 2014 Feb; 88(4):1942-52. Mahar JE, Donker NC, Bok K, Talbo GH, Green KY, Kirkwood CD. PMID: 24284328; PMCID: PMC3911557.
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    66. α7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles. Am J Pathol. 2014 Feb; 184(2):520-9. Medeiros R, Castello NA, Cheng D, Kitazawa M, Baglietto-Vargas D, Green KN, Esbenshade TA, Bitner RS, Decker MW, LaFerla FM. PMID: 24269557.
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    67. Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production. Neurobiol Aging. 2014 May; 35(5):1002-11. Rice RA, Berchtold NC, Cotman CW, Green KN. PMID: 24268883; PMCID: PMC3939046.
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    68. Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition. Neurobiol Dis. 2014 Feb; 62:407-15. Baglietto-Vargas D, Kitazawa M, Le EJ, Estrada-Hernandez T, Rodriguez-Ortiz CJ, Medeiros R, Green KN, LaFerla FM. PMID: 24176788.
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    71. Epidemiology and evolution of rotaviruses and noroviruses from an archival WHO Global Study in Children (1976-79) with implications for vaccine design. PLoS One. 2013; 8(3):e59394. Rackoff LA, Bok K, Green KY, Kapikian AZ. PMID: 23536875; PMCID: PMC3607611.
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    114. Stable expression of a Norwalk virus RNA replicon in a human hepatoma cell line. Virology. 2006 Sep 30; 353(2):463-73. Chang KO, Sosnovtsev SV, Belliot G, King AD, Green KY. PMID: 16843517.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimalsCells
    115. Genetically augmenting Abeta42 levels in skeletal muscle exacerbates inclusion body myositis-like pathology and motor deficits in transgenic mice. Am J Pathol. 2006 Jun; 168(6):1986-97. Kitazawa M, Green KN, Caccamo A, LaFerla FM. PMID: 16723713; PMCID: PMC1606633.
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    116. M1 receptors play a central role in modulating AD-like pathology in transgenic mice. Neuron. 2006 Mar 02; 49(5):671-82. Caccamo A, Oddo S, Billings LM, Green KN, Martinez-Coria H, Fisher A, LaFerla FM. PMID: 16504943.
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    117. A dynamic relationship between intracellular and extracellular pools of Abeta. Am J Pathol. 2006 Jan; 168(1):184-94. Oddo S, Caccamo A, Smith IF, Green KN, LaFerla FM. PMID: 16400022; PMCID: PMC1592652.
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    118. Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. J Neurosci. 2005 Sep 28; 25(39):8843-53. Kitazawa M, Oddo S, Yamasaki TR, Green KN, LaFerla FM. PMID: 16192374; PMCID: PMC6725603.
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    119. Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals. Cell Calcium. 2005 Sep-Oct; 38(3-4):427-37. Smith IF, Green KN, LaFerla FM. PMID: 16125228.
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    120. Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease. J Neurochem. 2005 Sep; 94(6):1711-8. Smith IF, Hitt B, Green KN, Oddo S, LaFerla FM. PMID: 16156741.
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    121. Feline calicivirus VP2 is essential for the production of infectious virions. J Virol. 2005 Apr; 79(7):4012-24. Sosnovtsev SV, Belliot G, Chang KO, Onwudiwe O, Green KY. PMID: 15767403; PMCID: PMC1061574.
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    122. Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron. 2005 Mar 03; 45(5):675-88. Billings LM, Oddo S, Green KN, McGaugh JL, LaFerla FM. PMID: 15748844.
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    123. Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):3046-51. Oddo S, Caccamo A, Green KN, Liang K, Tran L, Chen Y, Leslie FM, LaFerla FM. PMID: 15705720; PMCID: PMC549455.
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    124. Norovirus proteinase-polymerase and polymerase are both active forms of RNA-dependent RNA polymerase. J Virol. 2005 Feb; 79(4):2393-403. Belliot G, Sosnovtsev SV, Chang KO, Babu V, Uche U, Arnold JJ, Cameron CE, Green KY. PMID: 15681440; PMCID: PMC546540.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    125. Reverse genetics system for porcine enteric calicivirus, a prototype sapovirus in the Caliciviridae. J Virol. 2005 Feb; 79(3):1409-16. Chang KO, Sosnovtsev SV, Sosnovtsev SS, Belliot G, Wang Q, Saif LJ, Green KY. PMID: 15650167; PMCID: PMC544127.
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    126. Replication of Norovirus in cell culture reveals a tropism for dendritic cells and macrophages. PLoS Biol. 2004 Dec; 2(12):e432. Wobus CE, Karst SM, Thackray LB, Chang KO, Sosnovtsev SV, Belliot G, Krug A, Mackenzie JM, Green KY, Virgin HW. PMID: 15562321; PMCID: PMC532393.
      View in: PubMed   Mentions: 382     Fields:    Translation:AnimalsCells
    127. Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways. Brain Res Mol Brain Res. 2004 Nov 04; 130(1-2):161-9. Webster NJ, Green KN, Settle VJ, Peers C, Vaughan PF. PMID: 15519686.
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    128. Presenilin regulates capacitative calcium entry dependently and independently of gamma-secretase activity. Biochem Biophys Res Commun. 2004 Oct 01; 322(4):1145-52. Akbari Y, Hitt BD, Murphy MP, Dagher NN, Tseng BP, Green KN, Golde TE, LaFerla FM. PMID: 15336962.
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    129. Calicivirus 3C-like proteinase inhibits cellular translation by cleavage of poly(A)-binding protein. J Virol. 2004 Aug; 78(15):8172-82. Kuyumcu-Martinez M, Belliot G, Sosnovtsev SV, Chang KO, Green KY, Lloyd RE. PMID: 15254188; PMCID: PMC446144.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    130. Norwalk virus N-terminal nonstructural protein is associated with disassembly of the Golgi complex in transfected cells. J Virol. 2004 May; 78(9):4827-37. Fernandez-Vega V, Sosnovtsev SV, Belliot G, King AD, Mitra T, Gorbalenya A, Green KY. PMID: 15078964; PMCID: PMC387691.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    131. Mutagenesis of tyrosine 24 in the VPg protein is lethal for feline calicivirus. J Virol. 2004 May; 78(9):4931-5. Mitra T, Sosnovtsev SV, Green KY. PMID: 15078978; PMCID: PMC387666.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    132. Hypoxic remodelling of Ca2+ mobilization in type I cortical astrocytes: involvement of ROS and pro-amyloidogenic APP processing. J Neurochem. 2004 Feb; 88(4):869-77. Smith IF, Boyle JP, Green KN, Pearson HA, Peers C. PMID: 14756807.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    133. In vitro proteolytic processing of the MD145 norovirus ORF1 nonstructural polyprotein yields stable precursors and products similar to those detected in calicivirus-infected cells. J Virol. 2003 Oct; 77(20):10957-74. Belliot G, Sosnovtsev SV, Mitra T, Hammer C, Garfield M, Green KY. PMID: 14512545; PMCID: PMC224964.
      View in: PubMed   Mentions: 71     Fields:    Translation:Cells
    134. Amyloid peptide-mediated hypoxic regulation of Ca2+ channels in PC12 cells. Adv Exp Med Biol. 2003; 536:187-92. Peers C, Green KN, Boyle JP. PMID: 14635666.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    135. Cell-culture propagation of porcine enteric calicivirus mediated by intestinal contents is dependent on the cyclic AMP signaling pathway. Virology. 2002 Dec 20; 304(2):302-10. Chang KO, Kim Y, Green KY, Saif LJ. PMID: 12504571.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    136. Altered processing of amyloid precursor protein in the human neuroblastoma SH-SY5Y by chronic hypoxia. J Neurochem. 2002 Dec; 83(6):1262-71. Webster NJ, Green KN, Peers C, Vaughan PF. PMID: 12472881.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    137. Isolation of enzymatically active replication complexes from feline calicivirus-infected cells. J Virol. 2002 Sep; 76(17):8582-95. Green KY, Mory A, Fogg MH, Weisberg A, Belliot G, Wagner M, Mitra T, Ehrenfeld E, Cameron CE, Sosnovtsev SV. PMID: 12163578; PMCID: PMC136418.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    138. Processing map and essential cleavage sites of the nonstructural polyprotein encoded by ORF1 of the feline calicivirus genome. J Virol. 2002 Jul; 76(14):7060-72. Sosnovtsev SV, Garfield M, Green KY. PMID: 12072506; PMCID: PMC136307.
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