-
Microglial replacement in a Sandhoff disease mouse model reveals myeloid-derived β-hexosaminidase is necessary for neuronal health. Nat Commun. 2025 Aug 27; 16(1):7994.
Tsourmas KI, Butler CA, Kwang NE, Sloane ZR, Dykman KJG, Maloof GO, Choudhury BP, Paulchakrabarti M, Prekopa CA, Tabaie EZ, Krattli RP, El-Khatib SM, Swarup V, Acharya MM, Hohsfield LA, Green KN. PMID: 40866328; PMCID: PMC12391554.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Aggrecan protects against plaque accumulation and is essential for proper microglial responses to plaques. Cell Rep. 2025 Aug 26; 44(8):116064.
Barahona RA, Kwang NE, Kono-Soosaipillai AR, Rubio Salgado G, Tran KM, Lu YH, Reddy S, da Cunha C, Velazquez-Rivera E, Crapser JD, Xu X, Hohsfield LA, Green KN. PMID: 40748756; PMCID: PMC12445281.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Cerebrovascular alterations in a mouse model of late-onset Alzheimer's disease. Neurophotonics. 2025 Jan; 12(Suppl 1):S14614.
Crouzet C, Xie DF, Laquindanum Nuqui MN, Hasselman J, Phan T, Wilson RH, Baglietto-Vargas D, Da Cunha C, Davtyan H, Forner S, Jullienne A, Bazrafkan A, LaFerla FM, Obenaus A, Blurton-Jones M, Akbari Y, Green KN, Choi B. PMID: 40475700; PMCID: PMC12138534.
View in:
PubMed Mentions:
1
-
Identification of the velum interpositum as a meningeal-CNS route for myeloid cell trafficking into the brain. Neuron. 2025 Aug 06; 113(15):2455-2473.e6.
Hohsfield LA, Kim SJ, Barahona RA, Henningfield CM, Mansour K, Vallejo KD, Tsourmas KI, Kwang NE, Ghorbanian Y, Angulo JAA, Gao P, Pachow C, Inlay MA, Walsh CM, Xu X, Lane TE, Green KN. PMID: 40466634; PMCID: PMC12331438.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
CLU alleviates Alzheimer's disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density. Neuron. 2025 Jun 18; 113(12):1925-1946.e11.
Lish AM, Grogan EFL, Benoit CR, Pearse RV, Heuer SE, Luquez T, Orme GA, Galle PC, Milinkeviciute G, Green KN, Alexander KD, Fancher SB, Stern AM, Fujita M, Bennett DA, Seyfried NT, De Jager PL, Menon V, Young-Pearse TL. PMID: 40311610; PMCID: PMC12181066.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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A broadly protective human antibody for GI genogroup noroviruses. Nat Microbiol. 2025 May; 10(5):1227-1239.
Rimkute I, Olia AS, Suleiman M, Woods KD, Bylund T, Morano NC, Tully ES, Verardi R, Bao S, Beddall MH, Chaimongkol N, Donaldson MM, Du R, Dulan CNM, Gorman J, Henry AR, Schramm CA, Sosnovtsev SV, Stephens T, Todd JP, Tsybovsky Y, Douek DC, Green KY, Rawi R, Shapiro L, Zhou T, Kwong PD, Roederer M. PMID: 40211068.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Generation of an Inducible Destabilized-Domain Cre Mouse Line to Target Disease Associated Microglia. Glia. 2025 Jun; 73(6):1272-1287.
Henningfield CM, Ngo M, Murray KM, Kwang NE, Tsourmas KI, Neumann J, Pashkutz ZA, Kawauchi S, Swarup V, Lane TE, MacGregor GR, Green KN. PMID: 39988890; PMCID: PMC12309518.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology. Mol Neurodegener. 2025 Jan 22; 20(1):9.
Tran KM, Kwang NE, Butler CA, Gomez-Arboledas A, Kawauchi S, Mar C, Chao D, Barahona RA, Da Cunha C, Tsourmas KI, Shi Z, Wang S, Collins S, Walker A, Shi KX, Alcantara JA, Neumann J, Duong DM, Seyfried NT, Tenner AJ, LaFerla FM, Hohsfield LA, Swarup V, MacGregor GR, Green KN. PMID: 39844286; PMCID: PMC11752804.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Phase 2A Proof-of-Concept Double-Blind, Randomized, Placebo-Controlled Trial of Nicotinamide in Early Alzheimer Disease. Neurology. 2025 Jan 14; 104(1):e210152.
Grill JD, Tam S, Thai G, Vides B, Pierce AL, Green K, Gillen DL, Teng E, Kremen S, Beigi M, Rissman RA, Léger GC, Balasubramanian A, Revta C, Morrison R, Jennings R, Pa J, Zhang J, Jin S, Messer K, Feldman HH. PMID: 39671543; PMCID: PMC11655133.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCellsCTClinical Trials
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Bispecific antibodies targeting BCMA or GPRC5D are highly effective in relapsed myeloma after CAR T-cell therapy. Blood Cancer J. 2024 12 05; 14(1):214.
Merz M, Dima D, Hashmi H, Ahmed N, Stölzel F, Holderried TAW, Fenk R, Müller F, Tovar N, Oliver-Cáldes A, Rathje K, Davis JA, Fandrei D, Vucinic V, Kharboutli S, Baermann BN, Ayuk F, Platzbecker U, Albici AM, Schub N, Schmitz F, Shune L, Khouri J, Anwer F, Raza S, McGuirk J, Mahmoudjafari Z, Green K, Khandanpour C, Teichert M, Jeker B, Hoffmann M, Kröger N, von Tresckow B, de Larrea CF, Pabst T, Abdallah AO, Gagelmann N. PMID: 39632797; PMCID: PMC11618392.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's disease. Nat Genet. 2024 Dec; 56(12):2704-2717.
Miyoshi E, Morabito S, Henningfield CM, Das S, Rahimzadeh N, Shabestari SK, Michael N, Emerson N, Reese F, Shi Z, Cao Z, Srinivasan SS, Scarfone VM, Arreola MA, Lu J, Wright S, Silva J, Leavy K, Lott IT, Doran E, Yong WH, Shahin S, Perez-Rosendahl M, Alzheimer’s Biomarkers Consortium–Down Syndrome (ABC–DS), Head E, Green KN, Swarup V. PMID: 39578645; PMCID: PMC11631771.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Single-cell transcriptional analysis of murine norovirus infection in a human intestinal cell line. J Virol. 2024 Nov 19; 98(11):e0161724.
Matsushima Y, Levenson EA, Chaimongkol N, Harris L, Zhao Y, Turan S, Otaizo-Carrasquero F, Ganesan S, Hornick KM, Martens C, Sosnovtsev SV, Green KY. PMID: 39475272; PMCID: PMC11575399.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Myeloid-derived β-hexosaminidase is essential for neuronal health and lysosome function: implications for Sandhoff disease. bioRxiv. 2024 Oct 22.
Tsourmas KI, Butler CA, Kwang NE, Sloane ZR, Dykman KJG, Maloof GO, Prekopa CA, Krattli RP, El-Khatib SM, Swarup V, Acharya MM, Hohsfield LA, Green KN. PMID: 39484433; PMCID: PMC11526954.
View in:
PubMed Mentions:
-
Generation of an inducible destabilized-domain Cre mouse line to target disease associated microglia. bioRxiv. 2024 Sep 19.
Henningfield CM, Kwang N, Tsourmas KI, Neumann J, Kawauchi S, Swarup V, MacGregor GR, Green KN. PMID: 39345513; PMCID: PMC11429805.
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PubMed Mentions:
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Single-cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer's risk gene mutation. Mol Psychiatry. 2025 Feb; 30(2):461-477.
Johnston KG, Berackey BT, Tran KM, Gelber A, Yu Z, MacGregor GR, Mukamel EA, Tan Z, Green KN, Xu X. PMID: 39103533; PMCID: PMC11746152.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Cystatin F attenuates neuroinflammation and demyelination following murine coronavirus infection of the central nervous system. J Neuroinflammation. 2024 Jun 15; 21(1):157.
Syage AR, Pachow C, Murray KM, Henningfield C, Fernandez K, Du A, Cheng Y, Olivarria G, Kawauchi S, MacGregor GR, Green KN, Lane TE. PMID: 38879499; PMCID: PMC11179388.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology. bioRxiv. 2024 Jun 04.
Tran KM, Kwang N, Gomez-Arboledas A, Kawauchi S, Mar C, Chao D, Da Cunha C, Wang S, Collins S, Walker A, Shi KX, Alcantara JA, Neumann J, Tenner AJ, LaFerla FM, Hohsfield LA, Swarup V, MacGregor GR, Green KN. PMID: 38895362; PMCID: PMC11185750.
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PubMed Mentions:
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Selective targeting and modulation of plaque associated microglia via systemic hydroxyl dendrimer administration in an Alzheimer's disease mouse model. Alzheimers Res Ther. 2024 05 06; 16(1):101.
Henningfield CM, Soni N, Lee RW, Sharma R, Cleland JL, Green KN. PMID: 38711159; PMCID: PMC11071231.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Sex-specific associations between AD genotype and the microbiome of human amyloid beta knock-in (hAβ-KI) mice. Alzheimers Dement. 2024 07; 20(7):4935-4950.
Dunham SJB, Avelar-Barragan J, Rothman JA, Adams ED, Faraci G, Forner S, Kawauchi S, Tenner AJ, Green KN, LaFerla FM, MacGregor GR, Mapstone M, Whiteson KL. PMID: 38572865; PMCID: PMC11247698.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
The Abca7V1613M variant reduces Aβ generation, plaque load, and neuronal damage. Alzheimers Dement. 2024 07; 20(7):4914-4934.
Butler CA, Mendoza Arvilla A, Milinkeviciute G, Da Cunha C, Kawauchi S, Rezaie N, Liang HY, Javonillo D, Thach A, Wang S, Collins S, Walker A, Shi KX, Neumann J, Gomez-Arboledas A, Henningfield CM, Hohsfield LA, Mapstone M, Tenner AJ, LaFerla FM, Mortazavi A, MacGregor GR, Green KN. PMID: 38506634; PMCID: PMC11247689.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease. Alzheimers Dement. 2024 04; 20(4):2922-2942.
Garcia-Agudo LF, Shi Z, Smith IF, Kramár EA, Tran K, Kawauchi S, Wang S, Collins S, Walker A, Shi KX, Neumann J, Liang HY, Da Cunha C, Milinkeviciute G, Morabito S, Miyoshi E, Rezaie N, Gomez-Arboledas A, Arvilla AM, Ghaemi DI, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, Swarup V, MacGregor GR, Green KN. PMID: 38460121; PMCID: PMC11032570.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Genetic diversity promotes resilience in a mouse model of Alzheimer's disease. Alzheimers Dement. 2024 04; 20(4):2794-2816.
Soni N, Hohsfield LA, Tran KM, Kawauchi S, Walker A, Javonillo D, Phan J, Matheos D, Da Cunha C, Uyar A, Milinkeviciute G, Gomez-Arboledas A, Tran K, Kaczorowski CC, Wood MA, Tenner AJ, LaFerla FM, Carter GW, Mortazavi A, Swarup V, MacGregor GR, Green KN. PMID: 38426371; PMCID: PMC11032575.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Single cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer's risk gene mutation. Res Sq. 2023 Dec 07.
Johnston K, Berackey BB, Tran KM, Gelber A, Yu Z, MacGregor G, Mukamel EA, Tan Z, Green K, Xu X. PMID: 38106071; PMCID: PMC10723554.
View in:
PubMed Mentions:
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Microglia influence immune responses and restrict neurologic disease in response to central nervous system infection by a neurotropic murine coronavirus. Front Cell Neurosci. 2023; 17:1291255.
Syage A, Pachow C, Cheng Y, Mangale V, Green KN, Lane TE. PMID: 38099152; PMCID: PMC10719854.
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PubMed Mentions:
4
-
Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis. Nat Cell Biol. 2023 Dec; 25(12):1848-1859.
Evans KT, Blake K, Longworth A, Coburn MA, Insua-Rodríguez J, McMullen TP, Nguyen QH, Ma D, Lev T, Hernandez GA, Oganyan AK, Orujyan D, Edwards RA, Pridans C, Green KN, Villalta SA, Blurton-Jones M, Lawson DA. PMID: 37957324; PMCID: PMC11414741.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Norovirus evolves as one or more distinct clonal populations in immunocompromised hosts. mBio. 2023 Dec 19; 14(6):e0217723.
Chaimongkol N, Dábilla N, Tohma K, Matsushima Y, Yardley AB, Levenson EA, Johnson JA, Ahorrio C, Oler AJ, Kim DY, Souza M, Sosnovtsev SV, Parra GI, Green KY. PMID: 37905910; PMCID: PMC10746188.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
COVID-19 and the impact on Alzheimer's disease pathology. J Neurochem. 2024 Oct; 168(10):3415-3429.
Furman S, Green K, Lane TE. PMID: 37850241; PMCID: PMC11024062.
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PubMed Mentions:
7 Fields:
Translation:
HumansCellsPHPublic Health
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A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity. Nat Commun. 2023 10 16; 14(1):6516.
Salmen W, Hu L, Bok M, Chaimongkol N, Ettayebi K, Sosnovtsev SV, Soni K, Ayyar BV, Shanker S, Neill FH, Sankaran B, Atmar RL, Estes MK, Green KY, Parreño V, Prasad BVV. PMID: 37845211; PMCID: PMC10579229.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's Disease. bioRxiv. 2023 Jul 26.
Miyoshi E, Morabito S, Henningfield CM, Rahimzadeh N, Kiani Shabestari S, Das S, Michael N, Reese F, Shi Z, Cao Z, Scarfone V, Arreola MA, Lu J, Wright S, Silva J, Leavy K, Lott IT, Doran E, Yong WH, Shahin S, Perez-Rosendahl M, Head E, Green KN, Swarup V. PMID: 37546983; PMCID: PMC10402031.
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PubMed Mentions:
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Ablation of microglia following infection of the central nervous system with a neurotropic murine coronavirus infection leads to increased demyelination and impaired remyelination. J Neuroimmunol. 2023 08 15; 381:578133.
Cheng Y, Javonillo DI, Pachow C, Scarfone VM, Fernandez K, Walsh CM, Green KN, Lane TE. PMID: 37352687; PMCID: PMC11840753.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Clusterin/apolipoprotein J, its isoforms and Alzheimer's disease. Front Aging Neurosci. 2023; 15:1167886.
Milinkeviciute G, Green KN. PMID: 37122381; PMCID: PMC10133478.
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PubMed Mentions:
9
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Mucosal and systemic neutralizing antibodies to norovirus induced in infant mice orally inoculated with recombinant rotaviruses. Proc Natl Acad Sci U S A. 2023 02 28; 120(9):e2214421120.
Kawagishi T, Sánchez-Tacuba L, Feng N, Costantini VP, Tan M, Jiang X, Green KY, Vinjé J, Ding S, Greenberg HB. PMID: 36821582; PMCID: PMC9992845.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques. Mol Neurodegener. 2023 02 17; 18(1):12.
Tran KM, Kawauchi S, Kramár EA, Rezaie N, Liang HY, Sakr JS, Gomez-Arboledas A, Arreola MA, Cunha CD, Phan J, Wang S, Collins S, Walker A, Shi KX, Neumann J, Filimban G, Shi Z, Milinkeviciute G, Javonillo DI, Tran K, Gantuz M, Forner S, Swarup V, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, MacGregor GR, Green KN. PMID: 36803190; PMCID: PMC9938579.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer's disease. Neurobiol Dis. 2023 01; 176:105939.
Zhang H, Chen L, Johnston KG, Crapser J, Green KN, Ha NM, Tenner AJ, Holmes TC, Nitz DA, Xu X. PMID: 36462718; PMCID: PMC10187684.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Targeting NAAA counters dopamine neuron loss and symptom progression in mouse models of parkinsonism. Pharmacol Res. 2022 08; 182:106338.
Palese F, Pontis S, Realini N, Torrens A, Ahmed F, Assogna F, Pellicano C, Bossù P, Spalletta G, Green K, Piomelli D. PMID: 35781057; PMCID: PMC9733952.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Frequent Low-Dose Δ9-Tetrahydrocannabinol in Adolescence Disrupts Microglia Homeostasis and Disables Responses to Microbial Infection and Social Stress in Young Adulthood. Biol Psychiatry. 2022 12 01; 92(11):845-860.
Lee HL, Jung KM, Fotio Y, Squire E, Palese F, Lin L, Torrens A, Ahmed F, Mabou Tagne A, Ramirez J, Su S, Wong CR, Jung DH, Scarfone VM, Nguyen PU, Wood M, Green K, Piomelli D. PMID: 35750512; PMCID: PMC10629396.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
The question of the question: impactful implementation science to address the HIV epidemic. J Int AIDS Soc. 2022 04; 25(4):e25898.
Geng EH, Nash D, Phanuphak N, Green K, Solomon S, Grimsrud A, Sohn AH, Mayer KH, Bärnighausen T, Bekker LG. PMID: 35384312; PMCID: PMC8982316.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansPHPublic Health
-
Kidney function in tenofovir disoproxil fumarate-based oral pre-exposure prophylaxis users: a systematic review and meta-analysis of published literature and a multi-country meta-analysis of individual participant data. Lancet HIV. 2022 04; 9(4):e242-e253.
Schaefer R, Amparo da Costa Leite PH, Silva R, Abdool Karim Q, Akolo C, Cáceres CF, Dourado I, Green K, Hettema A, Hoornenborg E, Jana S, Kerschberger B, Mahler H, Matse S, McManus H, Molina JM, Reza-Paul S, Azwa I, Shahmanesh M, Taylor D, Vega-Ramirez H, Veloso VG, Baggaley R, Dalal S. PMID: 35271825; PMCID: PMC8964504.
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PubMed Mentions:
10 Fields:
Translation:
HumansPHPublic Health
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Commentary: How Do Microglia Regulate Neural Circuit Connectivity and Activity in the Adult Brain? Neurosci Insights. 2022; 17:26331055211071124.
Liu YJ, Green KN, Holmes TC, Xu X. PMID: 35098130; PMCID: PMC8796061.
View in:
PubMed Mentions:
1
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Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease. Front Neurosci. 2021; 15:785276.
Javonillo DI, Tran KM, Phan J, Hingco E, Kramár EA, da Cunha C, Forner S, Kawauchi S, Milinkeviciute G, Gomez-Arboledas A, Neumann J, Banh CE, Huynh M, Matheos DP, Rezaie N, Alcantara JA, Mortazavi A, Wood MA, Tenner AJ, MacGregor GR, Green KN, LaFerla FM. PMID: 35140584; PMCID: PMC8818877.
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PubMed Mentions:
83
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MAC2 is a long-lasting marker of peripheral cell infiltrates into the mouse CNS after bone marrow transplantation and coronavirus infection. Glia. 2022 05; 70(5):875-891.
Hohsfield LA, Tsourmas KI, Ghorbanian Y, Syage AR, Jin Kim S, Cheng Y, Furman S, Inlay MA, Lane TE, Green KN. PMID: 35025109; PMCID: PMC8930563.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Cortical diurnal rhythms remain intact with microglial depletion. Sci Rep. 2022 01 07; 12(1):114.
Barahona RA, Morabito S, Swarup V, Green KN. PMID: 34997092; PMCID: PMC8742049.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice. J Virol. 2022 02 23; 96(4):e0196921.
Olivarria GM, Cheng Y, Furman S, Pachow C, Hohsfield LA, Smith-Geater C, Miramontes R, Wu J, Burns MS, Tsourmas KI, Stocksdale J, Manlapaz C, Yong WH, Teijaro J, Edwards R, Green KN, Thompson LM, Lane TE. PMID: 34935438; PMCID: PMC8865461.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic mice. bioRxiv. 2021 Nov 17.
Olivarria GM, Cheng Y, Furman S, Pachow C, Hohsfield LA, Smith-Geater C, Miramontes R, Wu J, Burns MS, Tsourmas KI, Stocksdale J, Manlapaz C, Yong WH, Teijaro J, Edwards R, Green KN, Thompson LM, Lane TE. PMID: 34816260; PMCID: PMC8609895.
View in:
PubMed Mentions:
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Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease. Sci Data. 2021 10 15; 8(1):270.
Forner S, Kawauchi S, Balderrama-Gutierrez G, Kramár EA, Matheos DP, Phan J, Javonillo DI, Tran KM, Hingco E, da Cunha C, Rezaie N, Alcantara JA, Baglietto-Vargas D, Jansen C, Neumann J, Wood MA, MacGregor GR, Mortazavi A, Tenner AJ, LaFerla FM, Green KN. PMID: 34654824; PMCID: PMC8519958.
View in:
PubMed Mentions:
198 Fields:
Translation:
AnimalsCells
-
Microglia-specific ApoE knock-out does not alter Alzheimer's disease plaque pathogenesis or gene expression. Glia. 2022 02; 70(2):287-302.
Henningfield CM, Arreola MA, Soni N, Spangenberg EE, Green KN. PMID: 34643971; PMCID: PMC9308171.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
Microglial dyshomeostasis drives perineuronal net and synaptic loss in a CSF1R+/- mouse model of ALSP, which can be rescued via CSF1R inhibitors. Sci Adv. 2021 Aug; 7(35).
Arreola MA, Soni N, Crapser JD, Hohsfield LA, Elmore MRP, Matheos DP, Wood MA, Swarup V, Mortazavi A, Green KN. PMID: 34433559; PMCID: PMC8386924.
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PubMed Mentions:
33 Fields:
-
Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave. Elife. 2021 08 23; 10.
Hohsfield LA, Najafi AR, Ghorbanian Y, Soni N, Crapser J, Figueroa Velez DX, Jiang S, Royer SE, Kim SJ, Henningfield CM, Anderson A, Gandhi SP, Mortazavi A, Inlay MA, Green KN. PMID: 34423781; PMCID: PMC8425950.
View in:
PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
-
Microglia as hackers of the matrix: sculpting synapses and the extracellular space. Cell Mol Immunol. 2021 11; 18(11):2472-2488.
Crapser JD, Arreola MA, Tsourmas KI, Green KN. PMID: 34413489; PMCID: PMC8546068.
View in:
PubMed Mentions:
70 Fields:
Translation:
HumansAnimalsCells
-
Genome-wide analyses of human noroviruses provide insights on evolutionary dynamics and evidence of coexisting viral populations evolving under recombination constraints. PLoS Pathog. 2021 07; 17(7):e1009744.
Tohma K, Lepore CJ, Martinez M, Degiuseppe JI, Khamrin P, Saito M, Mayta H, Nwaba AUA, Ford-Siltz LA, Green KY, Galeano ME, Zimic M, Stupka JA, Gilman RH, Maneekarn N, Ushijima H, Parra GI. PMID: 34255807; PMCID: PMC8318288.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
-
Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology. Nat Commun. 2021 04 23; 12(1):2421.
Baglietto-Vargas D, Forner S, Cai L, Martini AC, Trujillo-Estrada L, Swarup V, Nguyen MMT, Do Huynh K, Javonillo DI, Tran KM, Phan J, Jiang S, Kramár EA, Nuñez-Diaz C, Balderrama-Gutierrez G, Garcia F, Childs J, Rodriguez-Ortiz CJ, Garcia-Leon JA, Kitazawa M, Shahnawaz M, Matheos DP, Ma X, Da Cunha C, Walls KC, Ager RR, Soto C, Gutierrez A, Moreno-Gonzalez I, Mortazavi A, Tenner AJ, MacGregor GR, Wood M, Green KN, LaFerla FM. PMID: 33893290; PMCID: PMC8065162.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansAnimals
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Ending AIDS in the Asia-Pacific region by 2030: are we on track? Policy, epidemiological and intervention insights. Sex Health. 2021 03; 18(1):1-4.
Green K, Schmidt HA, Vallely AJ, Zhang L, Kelly-Hanku A, Janamnuaysook R, Ong JJ. PMID: 33663685.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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On the utility of CSF1R inhibitors. Proc Natl Acad Sci U S A. 2021 01 26; 118(4).
Green KN, Hume DA. PMID: 33446486; PMCID: PMC7848745.
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PubMed Mentions:
17 Fields:
Translation:
Cells
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Microglia Elimination Increases Neural Circuit Connectivity and Activity in Adult Mouse Cortex. J Neurosci. 2021 02 10; 41(6):1274-1287.
Liu YJ, Spangenberg EE, Tang B, Holmes TC, Green KN, Xu X. PMID: 33380470; PMCID: PMC7888230.
View in:
PubMed Mentions:
79 Fields:
Translation:
AnimalsCells
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Model organism development and evaluation for late-onset Alzheimer's disease: MODEL-AD. Alzheimers Dement (N Y). 2020; 6(1):e12110.
Oblak AL, Forner S, Territo PR, Sasner M, Carter GW, Howell GR, Sukoff-Rizzo SJ, Logsdon BA, Mangravite LM, Mortazavi A, Baglietto-Vargas D, Green KN, MacGregor GR, Wood MA, Tenner AJ, LaFerla FM, Lamb BT, and The MODEL-AD, Consortium. PMID: 33283040; PMCID: PMC7683958.
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PubMed Mentions:
63
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Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNS. J Neuroinflammation. 2020 Sep 20; 17(1):279.
Hohsfield LA, Najafi AR, Ghorbanian Y, Soni N, Hingco EE, Kim SJ, Jue AD, Swarup V, Inlay MA, Green KN. PMID: 32951604; PMCID: PMC7504855.
View in:
PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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To Kill a Microglia: A Case for CSF1R Inhibitors. Trends Immunol. 2020 09; 41(9):771-784.
Green KN, Crapser JD, Hohsfield LA. PMID: 32792173; PMCID: PMC7484341.
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PubMed Mentions:
123 Fields:
Translation:
HumansCells
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Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain. EBioMedicine. 2020 Aug; 58:102919.
Crapser JD, Spangenberg EE, Barahona RA, Arreola MA, Hohsfield LA, Green KN. PMID: 32745992; PMCID: PMC7399129.
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PubMed Mentions:
121 Fields:
Translation:
HumansAnimalsCells
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Aging and Progression of Beta-Amyloid Pathology in Alzheimer's Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression. Antioxidants (Basel). 2020 Jul 21; 9(7).
Fernández-Mendívil C, Arreola MA, Hohsfield LA, Green KN, Lopez MG. PMID: 32708329; PMCID: PMC7402118.
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PubMed Mentions:
18
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Human norovirus targets enteroendocrine epithelial cells in the small intestine. Nat Commun. 2020 06 02; 11(1):2759.
Green KY, Kaufman SS, Nagata BM, Chaimongkol N, Kim DY, Levenson EA, Tin CM, Yardley AB, Johnson JA, Barletta ABF, Khan KM, Yazigi NA, Subramanian S, Moturi SR, Fishbein TM, Moore IN, Sosnovtsev SV. PMID: 32488028; PMCID: PMC7265440.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansCells
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Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system. Glia. 2020 11; 68(11):2345-2360.
Mangale V, Syage AR, Ekiz HA, Skinner DD, Cheng Y, Stone CL, Brown RM, O'Connell RM, Green KN, Lane TE. PMID: 32449994; PMCID: PMC7280614.
View in:
PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Retraction for Kim et al., "Newcastle Disease Virus Vector Producing Human Norovirus-Like Particles Induces Serum, Cellular, and Mucosal Immune Responses in Mice". J Virol. 2020 02 28; 94(6).
Kim SH, Chen S, Jiang X, Green KY, Samal SK. PMID: 32111812; PMCID: PMC7158728.
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PubMed Mentions: Fields:
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Generation of Norovirus-Specific T Cells From Human Donors With Extensive Cross-Reactivity to Variant Sequences: Implications for Immunotherapy. J Infect Dis. 2020 02 03; 221(4):578-588.
Hanajiri R, Sani GM, Saunders D, Hanley PJ, Chopra A, Mallal SA, Sosnovtsev SV, Cohen JI, Green KY, Bollard CM, Keller MD. PMID: 31562500; PMCID: PMC7325618.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease. Brain. 2020 01 01; 143(1):266-288.
Crapser JD, Ochaba J, Soni N, Reidling JC, Thompson LM, Green KN. PMID: 31848580; PMCID: PMC6935750.
View in:
PubMed Mentions:
84 Fields:
Translation:
HumansAnimalsCells
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ICTV Virus Taxonomy Profile: Caliciviridae. J Gen Virol. 2019 11; 100(11):1469-1470.
Vinjé J, Estes MK, Esteves P, Green KY, Katayama K, Knowles NJ, L'Homme Y, Martella V, Vennema H, White PA. PMID: 31573467; PMCID: PMC7011698.
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PubMed Mentions:
97 Fields:
Translation:
AnimalsCells
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Microglia Regulate Pruning of Specialized Synapses in the Auditory Brainstem. Front Neural Circuits. 2019; 13:55.
Milinkeviciute G, Henningfield CM, Muniak MA, Chokr SM, Green KN, Cramer KS. PMID: 31555101; PMCID: PMC6722190.
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PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
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Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model. Nat Commun. 2019 08 21; 10(1):3758.
Spangenberg E, Severson PL, Hohsfield LA, Crapser J, Zhang J, Burton EA, Zhang Y, Spevak W, Lin J, Phan NY, Habets G, Rymar A, Tsang G, Walters J, Nespi M, Singh P, Broome S, Ibrahim P, Zhang C, Bollag G, West BL, Green KN. PMID: 31434879; PMCID: PMC6704256.
View in:
PubMed Mentions:
440 Fields:
Translation:
HumansAnimalsCells
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A limited capacity for microglial repopulation in the adult brain. Glia. 2018 11; 66(11):2385-2396.
Najafi AR, Crapser J, Jiang S, Ng W, Mortazavi A, West BL, Green KN. PMID: 30370589; PMCID: PMC6269202.
View in:
PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
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Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice. Aging Cell. 2018 Dec; 17(6):e12832.
Elmore MRP, Hohsfield LA, Kramár EA, Soreq L, Lee RJ, Pham ST, Najafi AR, Spangenberg EE, Wood MA, West BL, Green KN. PMID: 30276955; PMCID: PMC6260908.
View in:
PubMed Mentions:
171 Fields:
Translation:
AnimalsCells
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Vesicle-Cloaked Virus Clusters Are Optimal Units for Inter-organismal Viral Transmission. Cell Host Microbe. 2018 08 08; 24(2):208-220.e8.
Santiana M, Ghosh S, Ho BA, Rajasekaran V, Du WL, Mutsafi Y, De Jésus-Diaz DA, Sosnovtsev SV, Levenson EA, Parra GI, Takvorian PM, Cali A, Bleck C, Vlasova AN, Saif LJ, Patton JT, Lopalco P, Corcelli A, Green KY, Altan-Bonnet N. PMID: 30092198; PMCID: PMC6226266.
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Gamma oscillations in the entorhinal-hippocampal circuit underlying memory and dementia. Neurosci Res. 2018 Apr; 129:40-46.
Nakazono T, Jun H, Blurton-Jones M, Green KN, Igarashi KM. PMID: 29438778; PMCID: PMC7059556.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss. Mol Neurodegener. 2017 09 18; 12(1):66.
Hernandez MX, Jiang S, Cole TA, Chu SH, Fonseca MI, Fang MJ, Hohsfield LA, Torres MD, Green KN, Wetsel RA, Mortazavi A, Tenner AJ. PMID: 28923083; PMCID: PMC5604420.
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PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
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Necroptosis activation in Alzheimer's disease. Nat Neurosci. 2017 Sep; 20(9):1236-1246.
Caccamo A, Branca C, Piras IS, Ferreira E, Huentelman MJ, Liang WS, Readhead B, Dudley JT, Spangenberg EE, Green KN, Belfiore R, Winslow W, Oddo S. PMID: 28758999.
View in:
PubMed Mentions:
245 Fields:
Translation:
HumansAnimalsCells
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Human Sera Collected between 1979 and 2010 Possess Blocking-Antibody Titers to Pandemic GII.4 Noroviruses Isolated over Three Decades. J Virol. 2017 07 15; 91(14).
Sharma S, Carlsson B, Czakó R, Vene S, Haglund M, Ludvigsson J, Larson G, Hammarström L, Sosnovtsev SV, Atmar RL, Green KY, Estes MK, Svensson L. PMID: 28468886; PMCID: PMC5487561.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Microglial repopulation resolves inflammation and promotes brain recovery after injury. Glia. 2017 06; 65(6):931-944.
Rice RA, Pham J, Lee RJ, Najafi AR, West BL, Green KN. PMID: 28251674; PMCID: PMC5395311.
View in:
PubMed Mentions:
134 Fields:
Translation:
AnimalsCells
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Identification of Human Junctional Adhesion Molecule 1 as a Functional Receptor for the Hom-1 Calicivirus on Human Cells. mBio. 2017 02 14; 8(1).
Sosnovtsev SV, Sandoval-Jaime C, Parra GI, Tin CM, Jones RW, Soden J, Barnes D, Freeth J, Smith AW, Green KY. PMID: 28196955; PMCID: PMC5312078.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Static and Evolving Norovirus Genotypes: Implications for Epidemiology and Immunity. PLoS Pathog. 2017 01; 13(1):e1006136.
Parra GI, Squires RB, Karangwa CK, Johnson JA, Lepore CJ, Sosnovtsev SV, Green KY. PMID: 28103318; PMCID: PMC5283768.
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PubMed Mentions:
147 Fields:
Translation:
HumansCells
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The Norovirus NS3 Protein Is a Dynamic Lipid- and Microtubule-Associated Protein Involved in Viral RNA Replication. J Virol. 2017 Feb 01; 91(3).
Cotton BT, Hyde JL, Sarvestani ST, Sosnovtsev SV, Green KY, White PA, Mackenzie JM. PMID: 27881660; PMCID: PMC5244318.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Elimination of microglia improves cognitive function following cranial irradiation. Sci Rep. 2016 08 12; 6:31545.
Acharya MM, Green KN, Allen BD, Najafi AR, Syage A, Minasyan H, Le MT, Kawashita T, Giedzinski E, Parihar VK, West BL, Baulch JE, Limoli CL. PMID: 27516055; PMCID: PMC4981848.
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PubMed Mentions:
141 Fields:
Translation:
AnimalsCells
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Inflammation in Alzheimer's disease: Lessons learned from microglia-depletion models. Brain Behav Immun. 2017 Mar; 61:1-11.
Spangenberg EE, Green KN. PMID: 27395435; PMCID: PMC5218993.
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PubMed Mentions:
164 Fields:
Translation:
AnimalsCells
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Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology. Brain. 2016 Apr; 139(Pt 4):1265-81.
Spangenberg EE, Lee RJ, Najafi AR, Rice RA, Elmore MR, Blurton-Jones M, West BL, Green KN. PMID: 26921617; PMCID: PMC5006229.
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PubMed Mentions:
375 Fields:
Translation:
AnimalsCells
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Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice. J Neuroinflammation. 2015 Aug 01; 12:139.
Dagher NN, Najafi AR, Kayala KM, Elmore MR, White TE, Medeiros R, West BL, Green KN. PMID: 26232154; PMCID: PMC4522109.
View in:
PubMed Mentions:
286 Fields:
Translation:
HumansAnimalsCells
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Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice. J Neurochem. 2015 Sep; 134(5):915-26.
Baglietto-Vargas D, Chen Y, Suh D, Ager RR, Rodriguez-Ortiz CJ, Medeiros R, Myczek K, Green KN, Baram TZ, LaFerla FM. PMID: 26077803; PMCID: PMC4792118.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus. J Neurosci. 2015 Jul 08; 35(27):9977-89.
Rice RA, Spangenberg EE, Yamate-Morgan H, Lee RJ, Arora RP, Hernandez MX, Tenner AJ, West BL, Green KN. PMID: 26156998; PMCID: PMC4495246.
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PubMed Mentions:
149 Fields:
Translation:
AnimalsCells
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Characterizing newly repopulated microglia in the adult mouse: impacts on animal behavior, cell morphology, and neuroinflammation. PLoS One. 2015; 10(4):e0122912.
Elmore MR, Lee RJ, West BL, Green KN. PMID: 25849463; PMCID: PMC4388515.
View in:
PubMed Mentions:
141 Fields:
Translation:
AnimalsCells
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Optical imaging in an Alzheimer's mouse model reveals amyloid-β-dependent vascular impairment. Neurophotonics. 2014 Jul; 1(1):011005.
Lin AJ, Liu G, Castello NA, Yeh JJ, Rahimian R, Lee G, Tsay V, Durkin AJ, Choi B, LaFerla FM, Chen Z, Green KN, Tromberg BJ. PMID: 25133200; PMCID: PMC4132842.
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PubMed Mentions:
27
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Newcastle disease virus vector producing human norovirus-like particles induces serum, cellular, and mucosal immune responses in mice. J Virol. 2014 Sep 01; 88(17):9718-27.
Kim SH, Chen S, Jiang X, Green KY, Samal SK. PMID: 24920815; PMCID: PMC4136303.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Advances in norovirus biology. Cell Host Microbe. 2014 Jun 11; 15(6):668-80.
Karst SM, Wobus CE, Goodfellow IG, Green KY, Virgin HW. PMID: 24922570; PMCID: PMC4113907.
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PubMed Mentions:
115 Fields:
Translation:
HumansCells
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Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain. Neuron. 2014 Apr 16; 82(2):380-97.
Elmore MR, Najafi AR, Koike MA, Dagher NN, Spangenberg EE, Rice RA, Kitazawa M, Matusow B, Nguyen H, West BL, Green KN. PMID: 24742461; PMCID: PMC4161285.
View in:
PubMed Mentions:
1034 Fields:
Translation:
AnimalsCells
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7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss. PLoS One. 2014; 9(3):e91453.
Castello NA, Nguyen MH, Tran JD, Cheng D, Green KN, LaFerla FM. PMID: 24614170; PMCID: PMC3948846.
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PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
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Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease. Neurobiol Dis. 2014 Apr; 64:107-17.
Chabrier MA, Cheng D, Castello NA, Green KN, LaFerla FM. PMID: 24440055; PMCID: PMC4072239.
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PubMed Mentions:
58 Fields:
Translation:
HumansAnimalsCells
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In vivo optical signatures of neuronal death in a mouse model of Alzheimer's disease. Lasers Surg Med. 2014 Jan; 46(1):27-33.
Lin AJ, Castello NA, Lee G, Green KN, Durkin AJ, Choi B, LaFerla F, Tromberg BJ. PMID: 24284732; PMCID: PMC4001800.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Identification and characterization of antibody-binding epitopes on the norovirus GII.3 capsid. J Virol. 2014 Feb; 88(4):1942-52.
Mahar JE, Donker NC, Bok K, Talbo GH, Green KY, Kirkwood CD. PMID: 24284328; PMCID: PMC3911557.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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α7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles. Am J Pathol. 2014 Feb; 184(2):520-9.
Medeiros R, Castello NA, Cheng D, Kitazawa M, Baglietto-Vargas D, Green KN, Esbenshade TA, Bitner RS, Decker MW, LaFerla FM. PMID: 24269557.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
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Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production. Neurobiol Aging. 2014 May; 35(5):1002-11.
Rice RA, Berchtold NC, Cotman CW, Green KN. PMID: 24268883; PMCID: PMC3939046.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition. Neurobiol Dis. 2014 Feb; 62:407-15.
Baglietto-Vargas D, Kitazawa M, Le EJ, Estrada-Hernandez T, Rodriguez-Ortiz CJ, Medeiros R, Green KN, LaFerla FM. PMID: 24176788.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Identification of a Broadly Cross-Reactive Epitope in the Inner Shell of the Norovirus Capsid. PLoS One. 2013; 8(6):e67592.
Parra GI, Azure J, Fischer R, Bok K, Sandoval-Jaime C, Sosnovtsev SV, Sander P, Green KY. PMID: 23805319; PMCID: PMC3689733.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Development of Norwalk virus-specific monoclonal antibodies with therapeutic potential for the treatment of Norwalk virus gastroenteritis. J Virol. 2013 Sep; 87(17):9547-57.
Chen Z, Sosnovtsev SV, Bok K, Parra GI, Makiya M, Agulto L, Green KY, Purcell RH. PMID: 23785216; PMCID: PMC3754140.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Epidemiology and evolution of rotaviruses and noroviruses from an archival WHO Global Study in Children (1976-79) with implications for vaccine design. PLoS One. 2013; 8(3):e59394.
Rackoff LA, Bok K, Green KY, Kapikian AZ. PMID: 23536875; PMCID: PMC3607611.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Structures of the compact helical core domains of feline calicivirus and murine norovirus VPg proteins. J Virol. 2013 May; 87(10):5318-30.
Leen EN, Kwok KY, Birtley JR, Simpson PJ, Subba-Reddy CV, Chaudhry Y, Sosnovtsev SV, Green KY, Prater SN, Tong M, Young JC, Chung LM, Marchant J, Roberts LO, Kao CC, Matthews S, Goodfellow IG, Curry S. PMID: 23487472; PMCID: PMC3648151.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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The importance of intergenic recombination in norovirus GII.3 evolution. J Virol. 2013 Apr; 87(7):3687-98.
Mahar JE, Bok K, Green KY, Kirkwood CD. PMID: 23325692; PMCID: PMC3624197.
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PubMed Mentions:
48 Fields:
Translation:
HumansCells
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Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology. Biol Psychiatry. 2013 Sep 01; 74(5):357-66.
Baglietto-Vargas D, Medeiros R, Martinez-Coria H, LaFerla FM, Green KN. PMID: 23312564; PMCID: PMC3633722.
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PubMed Mentions:
52 Fields:
Translation:
Animals
-
The feline calicivirus leader of the capsid protein is associated with cytopathic effect. J Virol. 2013 Mar; 87(6):3003-17.
Abente EJ, Sosnovtsev SV, Sandoval-Jaime C, Parra GI, Bok K, Green KY. PMID: 23269802; PMCID: PMC3592120.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Animal models of Alzheimer disease. Cold Spring Harb Perspect Med. 2012 Nov 01; 2(11).
LaFerla FM, Green KN. PMID: 23002015; PMCID: PMC3543097.
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PubMed Mentions:
202 Fields:
Translation:
HumansAnimalsCells
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Presenilin-null cells have altered two-pore calcium channel expression and lysosomal calcium: implications for lysosomal function. Brain Res. 2012 Dec 13; 1489:8-16.
Neely Kayala KM, Dickinson GD, Minassian A, Walls KC, Green KN, Laferla FM. PMID: 23103503; PMCID: PMC3516298.
View in:
PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
-
APP knockout mice experience acute mortality as the result of ischemia. PLoS One. 2012; 7(8):e42665.
Koike MA, Lin AJ, Pham J, Nguyen E, Yeh JJ, Rahimian R, Tromberg BJ, Choi B, Green KN, LaFerla FM. PMID: 22912719; PMCID: PMC3415410.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
Genetic knockdown of brain-derived neurotrophic factor in 3xTg-AD mice does not alter Aβ or tau pathology. PLoS One. 2012; 7(8):e39566.
Castello NA, Green KN, LaFerla FM. PMID: 22870188; PMCID: PMC3411687.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Swedish Alzheimer mutation induces mitochondrial dysfunction mediated by HSP60 mislocalization of amyloid precursor protein (APP) and beta-amyloid. J Biol Chem. 2012 Aug 31; 287(36):30317-27.
Walls KC, Coskun P, Gallegos-Perez JL, Zadourian N, Freude K, Rasool S, Blurton-Jones M, Green KN, LaFerla FM. PMID: 22753410; PMCID: PMC3436283.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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Calpain inhibitor A-705253 mitigates Alzheimer's disease-like pathology and cognitive decline in aged 3xTgAD mice. Am J Pathol. 2012 Aug; 181(2):616-25.
Medeiros R, Kitazawa M, Chabrier MA, Cheng D, Baglietto-Vargas D, Kling A, Moeller A, Green KN, LaFerla FM. PMID: 22688056.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
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Multiple antigenic sites are involved in blocking the interaction of GII.4 norovirus capsid with ABH histo-blood group antigens. J Virol. 2012 Jul; 86(13):7414-26.
Parra GI, Abente EJ, Sandoval-Jaime C, Sosnovtsev SV, Bok K, Green KY. PMID: 22532688; PMCID: PMC3416322.
View in:
PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
-
Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma. Cell Host Microbe. 2012 Apr 19; 11(4):397-409.
Hwang S, Maloney NS, Bruinsma MW, Goel G, Duan E, Zhang L, Shrestha B, Diamond MS, Dani A, Sosnovtsev SV, Green KY, Lopez-Otin C, Xavier RJ, Thackray LB, Virgin HW. PMID: 22520467; PMCID: PMC3348177.
View in:
PubMed Mentions:
166 Fields:
Translation:
HumansAnimalsCells
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Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544.
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, et al. PMID: 22966490; PMCID: PMC3404883.
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PubMed Mentions:
1868 Fields:
Translation:
HumansAnimals
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Comparative evolution of GII.3 and GII.4 norovirus over a 31-year period. J Virol. 2011 Sep; 85(17):8656-66.
Boon D, Mahar JE, Abente EJ, Kirkwood CD, Purcell RH, Kapikian AZ, Green KY, Bok K. PMID: 21715504; PMCID: PMC3165818.
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PubMed Mentions:
75 Fields:
Translation:
HumansCells
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Diversity of murine norovirus strains isolated from asymptomatic mice of different genetic backgrounds within a single U.S. research institute. PLoS One. 2011; 6(6):e21435.
Barron EL, Sosnovtsev SV, Bok K, Prikhodko V, Sandoval-Jaime C, Rhodes CR, Hasenkrug K, Carmody AB, Ward JM, Perdue K, Green KY. PMID: 21738664; PMCID: PMC3125191.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Presenilins mediate efficient proteolysis via the autophagosome-lysosome system. Autophagy. 2011 Jun; 7(6):664-5.
Neely KM, Green KN. PMID: 21460614.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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ST101 induces a novel 17 kDa APP cleavage that precludes Aβ generation in vivo. Ann Neurol. 2011 May; 69(5):831-44.
Green KN, Khashwji H, Estrada T, Laferla FM. PMID: 21416488.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a γ-secretase-independent manner. J Neurosci. 2011 Feb 23; 31(8):2781-91.
Neely KM, Green KN, LaFerla FM. PMID: 21414900; PMCID: PMC3064964.
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PubMed Mentions:
82 Fields:
Translation:
AnimalsCells
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Spatial frequency domain imaging of intrinsic optical property contrast in a mouse model of Alzheimer's disease. Ann Biomed Eng. 2011 Apr; 39(4):1349-57.
Lin AJ, Koike MA, Green KN, Kim JG, Mazhar A, Rice TB, LaFerla FM, Tromberg BJ. PMID: 21331663; PMCID: PMC3069335.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimals
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Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease. PLoS One. 2010 Nov 17; 5(11):e14015.
Parachikova A, Green KN, Hendrix C, LaFerla FM. PMID: 21103342; PMCID: PMC2984445.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimals
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Oligemic hypoperfusion differentially affects tau and amyloid-{beta}. Am J Pathol. 2010 Jul; 177(1):300-10.
Koike MA, Green KN, Blurton-Jones M, Laferla FM. PMID: 20472896; PMCID: PMC2893673.
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PubMed Mentions:
77 Fields:
Translation:
HumansAnimalsCells
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Reductions in amyloid-beta-derived neuroinflammation, with minocycline, restore cognition but do not significantly affect tau hyperphosphorylation. J Alzheimers Dis. 2010; 21(2):527-42.
Parachikova A, Vasilevko V, Cribbs DH, LaFerla FM, Green KN. PMID: 20555131; PMCID: PMC4085054.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
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Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice. Am J Pathol. 2010 Feb; 176(2):870-80.
Martinez-Coria H, Green KN, Billings LM, Kitazawa M, Albrecht M, Rammes G, Parsons CG, Gupta S, Banerjee P, LaFerla FM. PMID: 20042680; PMCID: PMC2808092.
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PubMed Mentions:
88 Fields:
Translation:
AnimalsCells
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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. J Cell Biol. 2009 Dec 28; 187(7):1083-99.
Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, Zeitlin SO, Finkbeiner S, Green KN, LaFerla FM, Bates G, Huang L, Patterson PH, Lo DC, Cuervo AM, Marsh JL, Steffan JS. PMID: 20026656; PMCID: PMC2806289.
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PubMed Mentions:
203 Fields:
Translation:
HumansAnimalsCells
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Evolutionary dynamics of GII.4 noroviruses over a 34-year period. J Virol. 2009 Nov; 83(22):11890-901.
Bok K, Abente EJ, Realpe-Quintero M, Mitra T, Sosnovtsev SV, Kapikian AZ, Green KY. PMID: 19759138; PMCID: PMC2772697.
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PubMed Mentions:
151 Fields:
Translation:
HumansCells
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Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity. J Biol Chem. 2009 Oct 23; 284(43):29427-36.
Aiken CT, Steffan JS, Guerrero CM, Khashwji H, Lukacsovich T, Simmons D, Purcell JM, Menhaji K, Zhu YZ, Green K, Laferla F, Huang L, Thompson LM, Marsh JL. PMID: 19710014; PMCID: PMC2785575.
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PubMed Mentions:
86 Fields:
Translation:
HumansCells
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Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology. J Cell Mol Med. 2009 Sep; 13(9A):2787-99.
Green KN. PMID: 19650832; PMCID: PMC4498936.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimals
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Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13594-9.
Blurton-Jones M, Kitazawa M, Martinez-Coria H, Castello NA, Müller FJ, Loring JF, Yamasaki TR, Poon WW, Green KN, LaFerla FM. PMID: 19633196; PMCID: PMC2715325.
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PubMed Mentions:
377 Fields:
Translation:
AnimalsCells
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Mouse norovirus replication is associated with virus-induced vesicle clusters originating from membranes derived from the secretory pathway. J Virol. 2009 Oct; 83(19):9709-19.
Hyde JL, Sosnovtsev SV, Green KY, Wobus C, Virgin HW, Mackenzie JM. PMID: 19587041; PMCID: PMC2748037.
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PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Apoptosis in murine norovirus-infected RAW264.7 cells is associated with downregulation of survivin. J Virol. 2009 Apr; 83(8):3647-56.
Bok K, Prikhodko VG, Green KY, Sosnovtsev SV. PMID: 19211757; PMCID: PMC2663291.
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PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
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Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau. J Neurosci. 2008 Nov 05; 28(45):11500-10.
Green KN, Steffan JS, Martinez-Coria H, Sun X, Schreiber SS, Thompson LM, LaFerla FM. PMID: 18987186; PMCID: PMC2617713.
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PubMed Mentions:
180 Fields:
Translation:
HumansAnimalsCells
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Relevance of transgenic mouse models to human Alzheimer disease. J Biol Chem. 2009 Mar 06; 284(10):6033-7.
Morrissette DA, Parachikova A, Green KN, LaFerla FM. PMID: 18948253.
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PubMed Mentions:
63 Fields:
Translation:
HumansAnimals
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SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. J Gen Physiol. 2008 Aug; 132(2):i1.
Green KN, Demuro A, Akbari Y, Hitt BD, Smith IF, Parker I, LaFerla FM. PMID: 18663130.
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PubMed Mentions:
15 Fields:
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Linking calcium to Abeta and Alzheimer's disease. Neuron. 2008 Jul 31; 59(2):190-4.
Green KN, LaFerla FM. PMID: 18667147.
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PubMed Mentions:
132 Fields:
Translation:
HumansAnimals
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Leader of the capsid protein in feline calicivirus promotes replication of Norwalk virus in cell culture. J Virol. 2008 Oct; 82(19):9306-17.
Chang KO, George DW, Patton JB, Green KY, Sosnovtsev SV. PMID: 18632864; PMCID: PMC2546961.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. J Cell Biol. 2008 Jun 30; 181(7):1107-16.
Green KN, Demuro A, Akbari Y, Hitt BD, Smith IF, Parker I, LaFerla FM. PMID: 18591429; PMCID: PMC2442205.
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PubMed Mentions:
148 Fields:
Translation:
HumansAnimalsCells
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Intracellular amyloid-beta in Alzheimer's disease. Nat Rev Neurosci. 2007 Jul; 8(7):499-509.
LaFerla FM, Green KN, Oddo S. PMID: 17551515.
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PubMed Mentions:
860 Fields:
Translation:
HumansAnimalsCells
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Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice. Neurobiol Dis. 2007 Oct; 28(1):76-82.
Clinton LK, Billings LM, Green KN, Caccamo A, Ngo J, Oddo S, McGaugh JL, LaFerla FM. PMID: 17659878; PMCID: PMC2756084.
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PubMed Mentions:
132 Fields:
Translation:
Animals
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Abeta inhibits the proteasome and enhances amyloid and tau accumulation. Neurobiol Aging. 2008 Nov; 29(11):1607-18.
Tseng BP, Green KN, Chan JL, Blurton-Jones M, LaFerla FM. PMID: 17544172; PMCID: PMC2664168.
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PubMed Mentions:
184 Fields:
Translation:
AnimalsCells
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Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels. J Neurosci. 2007 Apr 18; 27(16):4385-95.
Green KN, Martinez-Coria H, Khashwji H, Hall EB, Yurko-Mauro KA, Ellis L, LaFerla FM. PMID: 17442823; PMCID: PMC6672302.
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PubMed Mentions:
129 Fields:
Translation:
AnimalsCells
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Learning decreases A beta*56 and tau pathology and ameliorates behavioral decline in 3xTg-AD mice. J Neurosci. 2007 Jan 24; 27(4):751-61.
Billings LM, Green KN, McGaugh JL, LaFerla FM. PMID: 17251414; PMCID: PMC6672918.
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PubMed Mentions:
58 Fields:
Translation:
Animals
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Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease. J Neurosci. 2006 Aug 30; 26(35):9047-56.
Green KN, Billings LM, Roozendaal B, McGaugh JL, LaFerla FM. PMID: 16943563; PMCID: PMC6675335.
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PubMed Mentions:
304 Fields:
Translation:
AnimalsCells
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Cleavage map and proteolytic processing of the murine norovirus nonstructural polyprotein in infected cells. J Virol. 2006 Aug; 80(16):7816-31.
Sosnovtsev SV, Belliot G, Chang KO, Prikhodko VG, Thackray LB, Wobus CE, Karst SM, Virgin HW, Green KY. PMID: 16873239; PMCID: PMC1563789.
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PubMed Mentions:
112 Fields:
Translation:
AnimalsCells
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Stable expression of a Norwalk virus RNA replicon in a human hepatoma cell line. Virology. 2006 Sep 30; 353(2):463-73.
Chang KO, Sosnovtsev SV, Belliot G, King AD, Green KY. PMID: 16843517.
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PubMed Mentions:
115 Fields:
Translation:
HumansAnimalsCells
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Genetically augmenting Abeta42 levels in skeletal muscle exacerbates inclusion body myositis-like pathology and motor deficits in transgenic mice. Am J Pathol. 2006 Jun; 168(6):1986-97.
Kitazawa M, Green KN, Caccamo A, LaFerla FM. PMID: 16723713; PMCID: PMC1606633.
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PubMed Mentions:
21 Fields:
Translation:
Animals
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M1 receptors play a central role in modulating AD-like pathology in transgenic mice. Neuron. 2006 Mar 02; 49(5):671-82.
Caccamo A, Oddo S, Billings LM, Green KN, Martinez-Coria H, Fisher A, LaFerla FM. PMID: 16504943.
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PubMed Mentions:
173 Fields:
Translation:
HumansAnimals
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A dynamic relationship between intracellular and extracellular pools of Abeta. Am J Pathol. 2006 Jan; 168(1):184-94.
Oddo S, Caccamo A, Smith IF, Green KN, LaFerla FM. PMID: 16400022; PMCID: PMC1592652.
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PubMed Mentions:
130 Fields:
Translation:
AnimalsCells
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Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. J Neurosci. 2005 Sep 28; 25(39):8843-53.
Kitazawa M, Oddo S, Yamasaki TR, Green KN, LaFerla FM. PMID: 16192374; PMCID: PMC6725603.
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PubMed Mentions:
381 Fields:
Translation:
AnimalsCells
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Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals. Cell Calcium. 2005 Sep-Oct; 38(3-4):427-37.
Smith IF, Green KN, LaFerla FM. PMID: 16125228.
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PubMed Mentions:
59 Fields:
Translation:
HumansAnimals
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Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease. J Neurochem. 2005 Sep; 94(6):1711-8.
Smith IF, Hitt B, Green KN, Oddo S, LaFerla FM. PMID: 16156741.
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PubMed Mentions:
84 Fields:
Translation:
AnimalsCells
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Feline calicivirus VP2 is essential for the production of infectious virions. J Virol. 2005 Apr; 79(7):4012-24.
Sosnovtsev SV, Belliot G, Chang KO, Onwudiwe O, Green KY. PMID: 15767403; PMCID: PMC1061574.
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PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron. 2005 Mar 03; 45(5):675-88.
Billings LM, Oddo S, Green KN, McGaugh JL, LaFerla FM. PMID: 15748844.
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PubMed Mentions:
613 Fields:
Translation:
AnimalsCells
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Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):3046-51.
Oddo S, Caccamo A, Green KN, Liang K, Tran L, Chen Y, Leslie FM, LaFerla FM. PMID: 15705720; PMCID: PMC549455.
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PubMed Mentions:
85 Fields:
Translation:
AnimalsCells
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Norovirus proteinase-polymerase and polymerase are both active forms of RNA-dependent RNA polymerase. J Virol. 2005 Feb; 79(4):2393-403.
Belliot G, Sosnovtsev SV, Chang KO, Babu V, Uche U, Arnold JJ, Cameron CE, Green KY. PMID: 15681440; PMCID: PMC546540.
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PubMed Mentions:
29 Fields:
Translation:
Cells
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Reverse genetics system for porcine enteric calicivirus, a prototype sapovirus in the Caliciviridae. J Virol. 2005 Feb; 79(3):1409-16.
Chang KO, Sosnovtsev SV, Sosnovtsev SS, Belliot G, Wang Q, Saif LJ, Green KY. PMID: 15650167; PMCID: PMC544127.
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PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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Replication of Norovirus in cell culture reveals a tropism for dendritic cells and macrophages. PLoS Biol. 2004 Dec; 2(12):e432.
Wobus CE, Karst SM, Thackray LB, Chang KO, Sosnovtsev SV, Belliot G, Krug A, Mackenzie JM, Green KY, Virgin HW. PMID: 15562321; PMCID: PMC532393.
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PubMed Mentions:
414 Fields:
Translation:
AnimalsCells
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Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways. Brain Res Mol Brain Res. 2004 Nov 04; 130(1-2):161-9.
Webster NJ, Green KN, Settle VJ, Peers C, Vaughan PF. PMID: 15519686.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Presenilin regulates capacitative calcium entry dependently and independently of gamma-secretase activity. Biochem Biophys Res Commun. 2004 Oct 01; 322(4):1145-52.
Akbari Y, Hitt BD, Murphy MP, Dagher NN, Tseng BP, Green KN, Golde TE, LaFerla FM. PMID: 15336962.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Calicivirus 3C-like proteinase inhibits cellular translation by cleavage of poly(A)-binding protein. J Virol. 2004 Aug; 78(15):8172-82.
Kuyumcu-Martinez M, Belliot G, Sosnovtsev SV, Chang KO, Green KY, Lloyd RE. PMID: 15254188; PMCID: PMC446144.
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PubMed Mentions:
66 Fields:
Translation:
HumansCells
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Norwalk virus N-terminal nonstructural protein is associated with disassembly of the Golgi complex in transfected cells. J Virol. 2004 May; 78(9):4827-37.
Fernandez-Vega V, Sosnovtsev SV, Belliot G, King AD, Mitra T, Gorbalenya A, Green KY. PMID: 15078964; PMCID: PMC387691.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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Mutagenesis of tyrosine 24 in the VPg protein is lethal for feline calicivirus. J Virol. 2004 May; 78(9):4931-5.
Mitra T, Sosnovtsev SV, Green KY. PMID: 15078978; PMCID: PMC387666.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Hypoxic remodelling of Ca2+ mobilization in type I cortical astrocytes: involvement of ROS and pro-amyloidogenic APP processing. J Neurochem. 2004 Feb; 88(4):869-77.
Smith IF, Boyle JP, Green KN, Pearson HA, Peers C. PMID: 14756807.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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In vitro proteolytic processing of the MD145 norovirus ORF1 nonstructural polyprotein yields stable precursors and products similar to those detected in calicivirus-infected cells. J Virol. 2003 Oct; 77(20):10957-74.
Belliot G, Sosnovtsev SV, Mitra T, Hammer C, Garfield M, Green KY. PMID: 14512545; PMCID: PMC224964.
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PubMed Mentions:
72 Fields:
Translation:
Cells
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Amyloid peptide-mediated hypoxic regulation of Ca2+ channels in PC12 cells. Adv Exp Med Biol. 2003; 536:187-92.
Peers C, Green KN, Boyle JP. PMID: 14635666.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Cell-culture propagation of porcine enteric calicivirus mediated by intestinal contents is dependent on the cyclic AMP signaling pathway. Virology. 2002 Dec 20; 304(2):302-10.
Chang KO, Kim Y, Green KY, Saif LJ. PMID: 12504571.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Altered processing of amyloid precursor protein in the human neuroblastoma SH-SY5Y by chronic hypoxia. J Neurochem. 2002 Dec; 83(6):1262-71.
Webster NJ, Green KN, Peers C, Vaughan PF. PMID: 12472881.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Isolation of enzymatically active replication complexes from feline calicivirus-infected cells. J Virol. 2002 Sep; 76(17):8582-95.
Green KY, Mory A, Fogg MH, Weisberg A, Belliot G, Wagner M, Mitra T, Ehrenfeld E, Cameron CE, Sosnovtsev SV. PMID: 12163578; PMCID: PMC136418.
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PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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Processing map and essential cleavage sites of the nonstructural polyprotein encoded by ORF1 of the feline calicivirus genome. J Virol. 2002 Jul; 76(14):7060-72.
Sosnovtsev SV, Garfield M, Green KY. PMID: 12072506; PMCID: PMC136307.
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PubMed Mentions:
64 Fields:
Translation:
AnimalsCells
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Hypoxia potentiates exocytosis and Ca2+ channels in PC12 cells via increased amyloid beta peptide formation and reactive oxygen species generation. J Physiol. 2002 Jun 15; 541(Pt 3):1013-23.
Green KN, Boyle JP, Peers C. PMID: 12068059; PMCID: PMC2290370.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Divergent pathways account for two distinct effects of amyloid beta peptides on exocytosis and Ca(2+) currents: involvement of ROS and NF-kappaB. J Neurochem. 2002 Jun; 81(5):1043-51.
Green KN, Peers C. PMID: 12065617.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells