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Increased enhancer-promoter interactions during developmental enhancer activation in mammals. Nat Genet. 2024 Mar 20.
Chen Z, Snetkova V, Bower G, Jacinto S, Clock B, Dizehchi A, Barozzi I, Mannion BJ, Alcaina-Caro A, Lopez-Rios J, Dickel DE, Visel A, Pennacchio LA, Kvon EZ. PMID: 38509385.
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1 Fields:
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Rapid and Quantitative Functional Interrogation of Human Enhancer Variant Activity in Live Mice. bioRxiv. 2023 Dec 10.
Hollingsworth EW, Liu TA, Jacinto SH, Chen CX, Alcantara JA, Kvon EZ. PMID: 38105996; PMCID: PMC10723448.
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A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation. Science. 2022 10 07; 378(6615):68-78.
Yanchus C, Drucker KL, Kollmeyer TM, Tsai R, Winick-Ng W, Liang M, Malik A, Pawling J, De Lorenzo SB, Ali A, Decker PA, Kosel ML, Panda A, Al-Zahrani KN, Jiang L, Browning JWL, Lowden C, Geuenich M, Hernandez JJ, Gosio JT, Ahmed M, Loganathan SK, Berman J, Trcka D, Michealraj KA, Fortin J, Carson B, Hollingsworth EW, Jacinto S, Mazrooei P, Zhou L, Elia A, Lupien M, He HH, Murphy DJ, Wang L, Abyzov A, Dennis JW, Maass PG, Campbell K, Wilson MD, Lachance DH, Wrensch M, Wiencke J, Mak T, Pennacchio LA, Dickel DE, Visel A, Wrana J, Taylor MD, Zadeh G, Dirks P, Eckel-Passow JE, Attisano L, Pombo A, Ida CM, Kvon EZ, Jenkins RB, Schramek D. PMID: 36201590; PMCID: PMC9926876.
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9 Fields:
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HumansAnimalsCells
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Characterization of Mammalian In Vivo Enhancers Using Mouse Transgenesis and CRISPR Genome Editing. Methods Mol Biol. 2022; 2403:147-186.
Osterwalder M, Tran S, Hunter RD, Meky EM, von Maydell K, Harrington AN, Godoy J, Novak CS, Plajzer-Frick I, Zhu Y, Akiyama JA, Afzal V, Kvon EZ, Pennacchio LA, Dickel DE, Visel A. PMID: 34913122.
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8 Fields:
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AnimalsCells
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Author Correction: Enhancer redundancy in development and disease. Nat Rev Genet. 2021 May; 22(5):337.
Kvon EZ, Waymack R, Gad M, Wunderlich Z. PMID: 33850330.
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Ultraconserved enhancer function does not require perfect sequence conservation. Nat Genet. 2021 04; 53(4):521-528.
Snetkova V, Ypsilanti AR, Akiyama JA, Mannion BJ, Plajzer-Frick I, Novak CS, Harrington AN, Pham QT, Kato M, Zhu Y, Godoy J, Meky E, Hunter RD, Shi M, Kvon EZ, Afzal V, Tran S, Rubenstein JLR, Visel A, Pennacchio LA, Dickel DE. PMID: 33782603; PMCID: PMC8038972.
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20 Fields:
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HumansAnimalsCells
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Enhancer redundancy in development and disease. Nat Rev Genet. 2021 05; 22(5):324-336.
Kvon EZ, Waymack R, Gad M, Wunderlich Z. PMID: 33442000; PMCID: PMC8068586.
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PubMed Mentions:
71 Fields:
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HumansAnimalsCells
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Presynaptic Homeostasis Opposes Disease Progression in Mouse Models of ALS-Like Degeneration: Evidence for Homeostatic Neuroprotection. Neuron. 2020 07 08; 107(1):95-111.e6.
Orr BO, Hauswirth AG, Celona B, Fetter RD, Zunino G, Kvon EZ, Zhu Y, Pennacchio LA, Black BL, Davis GW. PMID: 32380032; PMCID: PMC7529479.
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22 Fields:
Translation:
AnimalsCells
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Comprehensive In Vivo Interrogation Reveals Phenotypic Impact of Human Enhancer Variants. Cell. 2020 03 19; 180(6):1262-1271.e15.
Kvon EZ, Zhu Y, Kelman G, Novak CS, Plajzer-Frick I, Kato M, Garvin TH, Pham Q, Harrington AN, Hunter RD, Godoy J, Meky EM, Akiyama JA, Afzal V, Tran S, Escande F, Gilbert-Dussardier B, Jean-Marçais N, Hudaiberdiev S, Ovcharenko I, Dobbs MB, Gurnett CA, Manouvrier-Hanu S, Petit F, Visel A, Dickel DE, Pennacchio LA. PMID: 32169219; PMCID: PMC7179509.
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56 Fields:
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HumansAnimalsCells
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Stable enhancers are active in development, and fragile enhancers are associated with evolutionary adaptation. Genome Biol. 2019 07 15; 20(1):140.
Li S, Kvon EZ, Visel A, Pennacchio LA, Ovcharenko I. PMID: 31307522; PMCID: PMC6631995.
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6 Fields:
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HumansAnimalsCells
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Progressive Loss of Function in a Limb Enhancer during Snake Evolution. Cell. 2016 Oct 20; 167(3):633-642.e11.
Kvon EZ, Kamneva OK, Melo US, Barozzi I, Osterwalder M, Mannion BJ, Tissières V, Pickle CS, Plajzer-Frick I, Lee EA, Kato M, Garvin TH, Akiyama JA, Afzal V, Lopez-Rios J, Rubin EM, Dickel DE, Pennacchio LA, Visel A. PMID: 27768887; PMCID: PMC5484524.
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135 Fields:
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AnimalsCells
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An Evolutionary Conserved Epigenetic Mark of Polycomb Response Elements Implemented by Trx/MLL/COMPASS. Mol Cell. 2016 07 21; 63(2):318-328.
Rickels R, Hu D, Collings CK, Woodfin AR, Piunti A, Mohan M, Herz HM, Kvon E, Shilatifard A. PMID: 27447986; PMCID: PMC4996622.
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36 Fields:
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HumansAnimalsCells
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Using transgenic reporter assays to functionally characterize enhancers in animals. Genomics. 2015 Sep; 106(3):185-192.
Kvon EZ. PMID: 26072435.
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33 Fields:
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AnimalsCells
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Genome-scale functional characterization of Drosophila developmental enhancers in vivo. Nature. 2014 Aug 07; 512(7512):91-5.
Kvon EZ, Kazmar T, Stampfel G, Yáñez-Cuna JO, Pagani M, Schernhuber K, Dickson BJ, Stark A. PMID: 24896182.
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241 Fields:
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AnimalsCells
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Deciphering the transcriptional cis-regulatory code. Trends Genet. 2013 Jan; 29(1):11-22.
Yáñez-Cuna JO, Kvon EZ, Stark A. PMID: 23102583.
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60 Fields:
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HumansAnimalsCells
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Uncovering cis-regulatory sequence requirements for context-specific transcription factor binding. Genome Res. 2012 Oct; 22(10):2018-30.
Yáñez-Cuna JO, Dinh HQ, Kvon EZ, Shlyueva D, Stark A. PMID: 22534400; PMCID: PMC3460196.
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66 Fields:
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HumansAnimalsCells
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HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature. Genes Dev. 2012 May 01; 26(9):908-13.
Kvon EZ, Stampfel G, Yáñez-Cuna JO, Dickson BJ, Stark A. PMID: 22499593; PMCID: PMC3347788.
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77 Fields:
Translation:
AnimalsCells
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[Chromatin decompaction in the interbands of Drosophila polytene chromosomes does not correlate with high transcription level]. Genetika. 2011 Jun; 47(6):765-73.
Kvon EZ, Demakov SA, Zhimulev IF. PMID: 21866857.
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1 Fields:
Translation:
AnimalsCells
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[Functional organization of interbands in Drosophila polytene chromosomes]. Genetika. 2010 Oct; 46(10):1421-3.
Demakov SA, Andreenkov OV, Berkaeva MB, Vatolina TIu, Volkova EI, Kvon EZ, Semeshin VF, Zhimulev IF. PMID: 21254569.
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AnimalsCells
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Gene density profile reveals the marking of late replicated domains in the Drosophila melanogaster genome. Chromosoma. 2010 Dec; 119(6):589-600.
Belyakin SN, Babenko VN, Maksimov DA, Shloma VV, Kvon EZ, Belyaeva ES, Zhimulev IF. PMID: 20602235.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells