Daniele Piomelli

Title(s)Professor, Anatomy and Neurobiology
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-9179, 7080
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    Collapse Research 
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    The lipid amidase NAAA as a therapeutic target for Alzheimer's disease
    NIH RF1AG065329Sep 15, 2020 - Aug 31, 2024
    Role: Principal Investigator
    Peripheral FAAH inhibitor, URB937, as an opioid-sparing analgesic for chronic pain.
    NIH R41NS106999Sep 30, 2018 - Sep 29, 2020
    Role: Principal Investigator
    ICAL: Impact of Cannabinoids Across Lifespan
    NIH P50DA044118Jul 1, 2018 - May 31, 2022
    Role: Principal Investigator
    Peripheral FAAH as a target for novel analgesics
    NIH R42DA033683Mar 15, 2017 - Nov 30, 2020
    Role: Principal Investigator
    A Protective role for 2-AG in age-dependent cognitive impairment.
    NIH R21AG052336Aug 15, 2016 - May 31, 2018
    Role: Principal Investigator
    Lipidomics analysis of identified single neurons in the adult rodent brain
    NIH R21DA041776Apr 1, 2016 - Mar 31, 2018
    Role: Principal Investigator
    A new treatment for NSAID-associated gastrointestinal damage
    NIH R41DK104489Jul 1, 2015 - Jun 30, 2016
    Role: Principal Investigator
    Optimization and preclinical development of FAAH inhibitors for smoking cessation
    NIH DP1DA031387Sep 30, 2010 - Jul 31, 2016
    Role: Principal Investigator
    Lipid biosignatures of drug addiction
    NIH RC2DA028902Sep 30, 2009 - Aug 31, 2012
    Role: Principal Investigator
    Role of endocannabinoid signaling in stress-coping behavior
    NIH RL1AA017538Sep 30, 2007 - Jun 30, 2012
    Role: Principal Investigator
    Role of oleoylethanolamide in the control of food intake
    NIH R01DK073955Apr 1, 2007 - Jun 30, 2011
    Role: Principal Investigator
    Role of Endocannabinoids in the Behavioral Consequences of Social Isolation
    NIH R21DA022702Sep 30, 2006 - Jul 31, 2010
    Role: Principal Investigator
    Oleylethanolamide derivatives as anti-obesity agents
    NIH R41DK070347Sep 20, 2005 - Aug 31, 2006
    Role: Principal Investigator
    NIH T32DA007318Sep 1, 2001 - Jun 30, 2008
    Role: Principal Investigator
    NIH R01DA012653Aug 1, 1999 - May 31, 2005
    Role: Principal Investigator
    Characterization of Anandamide Transport in Brain
    NIH R01DA012413Aug 14, 1998 - Jun 30, 2017
    Role: Principal Investigator
    Characterization of a novel brain cannabinoid ligand
    NIH R01DA012447Aug 14, 1998 - Jul 31, 2011
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Diet-Induced Obesity Disrupts Histamine-Dependent Oleoylethanolamide Signaling in the Mouse Liver. Pharmacology. 2022 Jun 10; 1-10. Lin L, Mabou Tagne A, Squire EN, Lee HL, Fotio Y, Ramirez J, Zheng M, Torrens A, Ahmed F, Ramos R, Plikus MV, Piomelli D. PMID: 35691287.
      View in: PubMed   Mentions:
    2. Comparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male and Female Rats. Cannabis Cannabinoid Res. 2022 Mar 28. Torrens A, Roy P, Lin L, Vu C, Grimes D, Inshishian VC, Montesinos JS, Ahmed F, Mahler SV, Huestis MA, Das A, Piomelli D. PMID: 35353551.
      View in: PubMed   Mentions:
    3. Reduced DMPC and PMPC in lung surfactant promote SARS-CoV-2 infection in obesity. Metabolism. 2022 06; 131:155181. Du K, Sun L, Luo Z, Cao Y, Sun Q, Zhang K, Faizy A, Piomelli D, Lu X, Shan J, Yang Q. PMID: 35311662; PMCID: PMC8930181.
      View in: PubMed   Mentions:
    4. Call for Special Issue Papers: Sex and Gender Differences: Focus on Cannabis and Cannabinoids. Cannabis Cannabinoid Res. 2022 02; 7(1):1-2. Piomelli D. PMID: 35100054; PMCID: PMC8864728.
      View in: PubMed   Mentions:
    5. Call for Special Issue Papers: Sex and Gender Differences: Focus on Cannabis and Cannabinoids. Cannabis Cannabinoid Res. 2021 12; 6(6):449-450. Piomelli D. PMID: 34898257; PMCID: PMC8817679.
      View in: PubMed   Mentions:
    6. Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase. J Enzyme Inhib Med Chem. 2021 Dec; 36(1):1411-1423. Ghidini A, Scalvini L, Palese F, Lodola A, Mor M, Piomelli D. PMID: 34256657; PMCID: PMC8279155.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    7. Cannabinoids and Cancer Chemotherapy-Associated Adverse Effects. J Natl Cancer Inst Monogr. 2021 11 28; 2021(58):78-85. Ward SJ, Lichtman AH, Piomelli D, Parker LA. PMID: 34850893; PMCID: PMC8848502.
      View in: PubMed   Mentions:
    8. Persistent sexually dimorphic effects of adolescent THC exposure on hippocampal synaptic plasticity and episodic memory in rodents. Neurobiol Dis. 2022 01; 162:105565. Le AA, Quintanilla J, Amani M, Piomelli D, Lynch G, Gall CM. PMID: 34838664.
      View in: PubMed   Mentions:
    9. NAAA-regulated lipid signaling governs the transition from acute to chronic pain. Sci Adv. 2021 Oct 22; 7(43):eabi8834. Fotio Y, Jung KM, Palese F, Obenaus A, Tagne AM, Lin L, Rashid TI, Pacheco R, Jullienne A, Ramirez J, Mor M, Spadoni G, Jang C, Hohmann AG, Piomelli D. PMID: 34678057; PMCID: PMC8535814.
      View in: PubMed   Mentions:    Fields:    
    10. Publisher Correction: Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin. Sci Rep. 2021 Oct 07; 11(1):20330. Lai M, Amato R, La Rocca V, Bilgin M, Freer G, Spezia P, Quaranta P, Piomelli D, Pistello M. PMID: 34621010; PMCID: PMC8497496.
      View in: PubMed   Mentions:    Fields:    
    11. Endocannabinoid-Based Therapies. Annu Rev Pharmacol Toxicol. 2022 01 06; 62:483-507. Piomelli D, Mabou Tagne A. PMID: 34516291.
      View in: PubMed   Mentions:    Fields:    
    12. Pharmacokinetic and pharmacodynamic properties of aerosolized ("vaped") THC in adolescent male and female rats. Psychopharmacology (Berl). 2021 Dec; 238(12):3595-3605. Ruiz CM, Torrens A, Lallai V, Castillo E, Manca L, Martinez MX, Justeson DN, Fowler CD, Piomelli D, Mahler SV. PMID: 34495367; PMCID: PMC8665923.
      View in: PubMed   Mentions:    Fields:    
    13. Frequent Δ9- tetrahydrocannabinol exposure during adolescence impairs sociability in adult mice exposed to an aversive painful stimulus. Eur Neuropsychopharmacol. 2021 12; 53:19-24. Mabou Tagne A, Fotio Y, Alan Springs Z, Su S, Piomelli D. PMID: 34358818.
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    14. Pancreatic Pain-Knowledge Gaps and Research Opportunities in Children and Adults: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas. 2021 08 01; 50(7):906-915. Uc A, Andersen DK, Apkarian AV, Bellin MD, Colloca L, Drewes AM, Dunbar EK, Forsmark CE, Goodman MT, Kapural L, Koob GF, Palermo TM, Pandol SJ, Pasricha P, Phillips AE, Piomelli D, Saloman JL, Schwarzenberg SJ, Singh VK, Sowa G, Strouse T, Treisman GJ, Windsor JA, Yadav D. PMID: 34643606.
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    15. Persistent Exposure to Δ9-Tetrahydrocannabinol during Adolescence Does Not Affect Nociceptive Responding in Adult Mice. J Pharmacol Exp Ther. 2021 09; 378(3):215-221. Mabou Tagne A, Fotio Y, Ibne Rashid T, Piomelli D. PMID: 34183435.
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    16. Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin. Sci Rep. 2021 05 27; 11(1):11221. Lai M, Amato R, La Rocca V, Bilgin M, Freer G, Spezia P, Quaranta P, Piomelli D, Pistello M. PMID: 34045496; PMCID: PMC8159975.
      View in: PubMed   Mentions: 1     Fields:    
    17. Antinociceptive Profile of ARN19702, (2-Ethylsulfonylphenyl)-[(2S)-4-(6-fluoro-1,3-benzothiazol-2-yl)-2-methylpiperazin-1-yl]methanone, a Novel Orally Active N-Acylethanolamine Acid Amidase Inhibitor, in Animal Models. J Pharmacol Exp Ther. 2021 08; 378(2):70-76. Fotio Y, Sasso O, Ciccocioppo R, Piomelli D. PMID: 33986036.
      View in: PubMed   Mentions:    Fields:    
    18. Ablation of Acid Ceramidase Impairs Autophagy and Mitochondria Activity in Melanoma Cells. Int J Mol Sci. 2021 Mar 23; 22(6). Lai M, La Rocca V, Amato R, Freer G, Costa M, Spezia PG, Quaranta P, Lombardo G, Piomelli D, Pistello M. PMID: 33806766; PMCID: PMC8004726.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    19. Palmitoylethanolamide and hemp oil extract exert synergistic anti-nociceptive effects in mouse models of acute and chronic pain. Pharmacol Res. 2021 05; 167:105545. Mabou Tagne A, Fotio Y, Lin L, Squire E, Ahmed F, Rashid TI, Karimian Azari E, Piomelli D. PMID: 33722712.
      View in: PubMed   Mentions: 3     Fields:    
    20. Ceramide contributes to pathogenesis and may be targeted for therapy in VCP inclusion body myopathy. Hum Mol Genet. 2021 02 25; 29(24):3945-3953. Weiss L, Jung KM, Nalbandian A, Llewellyn K, Yu H, Ta L, Chang I, Migliore M, Squire E, Ahmed F, Piomelli D, Kimonis V. PMID: 33410456; PMCID: PMC8485215.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    21. Impact of Circulating N-Acylethanolamine Levels with Clinical and Laboratory End Points in Hemodialysis Patients. Am J Nephrol. 2021; 52(1):59-68. Pai AY, Wenziger C, Streja E, Argueta DA, DiPatrizio NV, Rhee CM, Vaziri ND, Kalantar-Zadeh K, Piomelli D, Moradi H. PMID: 33601382; PMCID: PMC7987690.
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    22. Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis. Mol Metab. 2021 05; 47:101174. Hundahl C, Kotzbeck P, Burm HB, Christiansen SH, Torz L, Helge AW, Madsen MP, Ratner C, Serup AK, Thompson JJ, Eichmann TO, Pers TH, Woldbye DPD, Piomelli D, Kiens B, Zechner R, Skov LJ, Holst B. PMID: 33549847; PMCID: PMC7903013.
      View in: PubMed   Mentions:    Fields:    
    23. The endocannabinoid system in the adipose organ. Rev Endocr Metab Disord. 2022 02; 23(1):51-60. Jung KM, Lin L, Piomelli D. PMID: 33387286; PMCID: PMC8776163.
      View in: PubMed   Mentions: 1     Fields:    
    24. Cannabinoids in periodontal disease amid the COVID-19 pandemic. J Periodontal Implant Sci. 2020 Dec; 50(6):355-357. Park JB, Jung KM, Piomelli D. PMID: 33350175; PMCID: PMC7758300.
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    25. Retraction Note: Cannabinoid type 1 receptor availability in the amygdala mediates threat processing in trauma survivors. Neuropsychopharmacology. 2020 Dec; 45(13):2302. Pietrzak RH, Huang Y, Corsi-Travali S, Zheng MQ, Lin SF, Henry S, Potenza MN, Piomelli D, Carson RE, Neumeister A. PMID: 32901117; PMCID: PMC7785013.
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    26. Characterization of the peripheral FAAH inhibitor, URB937, in animal models of acute and chronic migraine. Neurobiol Dis. 2021 01; 147:105157. Greco R, Demartini C, Zanaboni A, Casini I, De Icco R, Reggiani A, Misto A, Piomelli D, Tassorelli C. PMID: 33129939.
      View in: PubMed   Mentions: 2     Fields:    
    27. N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats. Psychopharmacology (Berl). 2021 Jan; 238(1):249-258. Fotio Y, Ciccocioppo R, Piomelli D. PMID: 33037452; PMCID: PMC7796956.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    28. NAPE-specific phospholipase D regulates LRRK2 association with neuronal membranes. Adv Pharmacol. 2021; 90:217-238. Palese F, Pontis S, Realini N, Piomelli D. PMID: 33706934.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    29. Pharmacokinetic, behavioral, and brain activity effects of Δ9-tetrahydrocannabinol in adolescent male and female rats. Neuropsychopharmacology. 2021 04; 46(5):959-969. Ruiz CM, Torrens A, Castillo E, Perrone CR, Cevallos J, Inshishian VC, Harder EV, Justeson DN, Huestis MA, Swarup V, Piomelli D, Mahler SV. PMID: 32927465; PMCID: PMC8115040.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    30. N-Acylethanolamine Acid Amidase contributes to disease progression in a mouse model of multiple sclerosis. Pharmacol Res. 2020 10; 160:105064. Pontis S, Palese F, Summa M, Realini N, Lanfranco M, De Mei C, Piomelli D. PMID: 32634582.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    31. Cannabinoid CB2 receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear. Neuropsychopharmacology. 2020 07; 45(8):1330-1338. Ivy D, Palese F, Vozella V, Fotio Y, Yalcin A, Ramirez G, Mears D, Wynn G, Piomelli D. PMID: 32375160; PMCID: PMC7298057.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    32. Comparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male Mice. J Pharmacol Exp Ther. 2020 07; 374(1):151-160. Torrens A, Vozella V, Huff H, McNeil B, Ahmed F, Ghidini A, Mahler SV, Huestis MA, Das A, Piomelli D. PMID: 32345621; PMCID: PMC7318794.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    33. The Synthetic Cannabinoid URB447 Reduces Brain Injury and the Associated White Matter Demyelination after Hypoxia-Ischemia in Neonatal Rats. ACS Chem Neurosci. 2020 05 06; 11(9):1291-1299. Carloni S, Crinelli R, Palma L, Álvarez FJ, Piomelli D, Duranti A, Balduini W, Alonso-Alconada D. PMID: 32271539; PMCID: PMC7997380.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    34. Inhibition of fatty acid amide hydrolase in the CNS prevents and reverses morphine tolerance in male and female mice. Br J Pharmacol. 2020 07; 177(13):3024-3035. Fotio Y, Palese F, Guaman Tipan P, Ahmed F, Piomelli D. PMID: 32077093; PMCID: PMC7280000.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    35. N-Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition. J Med Chem. 2020 07 23; 63(14):7475-7490. Piomelli D, Scalvini L, Fotio Y, Lodola A, Spadoni G, Tarzia G, Mor M. PMID: 32191459.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    36. Next Stop for Fatty Acid Amide Hydrolase Inhibitors, the Clinic? Biol Psychiatry. 2020 03 15; 87(6):485-486. Piomelli D. PMID: 32081250.
      View in: PubMed   Mentions: 1     Fields:    
    37. Neurological Impairments in Mice Subjected to Irradiation and Chemotherapy. Radiat Res. 2020 05; 193(5):407-424. Dey D, Parihar VK, Szabo GG, Klein PM, Tran J, Moayyad J, Ahmed F, Nguyen QA, Murry A, Merriott D, Nguyen B, Goldman J, Angulo MC, Piomelli D, Soltesz I, Baulch JE, Limoli CL. PMID: 32134362; PMCID: PMC7334540.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    38. Exposure to the cannabinoid agonist WIN 55, 212-2 in adolescent rats causes sleep alterations that persist until adulthood. Eur J Pharmacol. 2020 May 05; 874:172911. Macías-Triana L, Romero-Cordero K, Tatum-Kuri A, Vera-Barrón A, Millán-Aldaco D, Arankowsky-Sandoval G, Piomelli D, Murillo-Rodríguez E. PMID: 32045604.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    39. Circulating Endocannabinoids and Mortality in Hemodialysis Patients. Am J Nephrol. 2020; 51(2):86-95. Moradi H, Park C, Streja E, Argueta DA, DiPatrizio NV, You AS, Rhee CM, Vaziri ND, Kalantar-Zadeh K, Piomelli D. PMID: 31935741; PMCID: PMC7158229.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    40. Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign. Eur J Med Chem. 2020 Mar 01; 189:112047. Linciano P, Cullia G, Borsari C, Santucci M, Ferrari S, Witt G, Gul S, Kuzikov M, Ellinger B, Santarém N, Cordeiro da Silva A, Conti P, Bolognesi ML, Roberti M, Prati F, Bartoccini F, Retini M, Piersanti G, Cavalli A, Goldoni L, Bertozzi SM, Bertozzi F, Brambilla E, Rizzo V, Piomelli D, Pinto A, Bandiera T, Costi MP. PMID: 31982652.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    41. Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines. J Med Chem. 2020 02 13; 63(3):1261-1280. Castelli R, Scalvini L, Vacondio F, Lodola A, Anselmi M, Vezzosi S, Carmi C, Bassi M, Ferlenghi F, Rivara S, Møller IR, Rand KD, Daglian J, Wei D, Dotsey EY, Ahmed F, Jung KM, Stella N, Singh S, Mor M, Piomelli D. PMID: 31714779.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    42. A protective role for N-acylphosphatidylethanolamine phospholipase D in 6-OHDA-induced neurodegeneration. Sci Rep. 2019 11 04; 9(1):15927. Palese F, Pontis S, Realini N, Piomelli D. PMID: 31685899; PMCID: PMC6828692.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    43. FAAH inhibition as a preventive treatment for migraine: A pre-clinical study. Neurobiol Dis. 2020 02; 134:104624. Greco R, Demartini C, Zanaboni AM, Tumelero E, Reggiani A, Misto A, Piomelli D, Tassorelli C. PMID: 31629892.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    44. Pharmacokinetics, pharmacodynamics and safety studies on URB937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats. J Pharm Pharmacol. 2019 Dec; 71(12):1762-1773. Vozella V, Ahmed F, Choobchian P, Merrill CB, Zibardi C, Tarzia G, Mor M, Duranti A, Tontini A, Rivara S, Piomelli D. PMID: 31579946; PMCID: PMC6842052.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    45. Waiting for the Entourage. Cannabis Cannabinoid Res. 2019; 4(3):137-138. Piomelli D. PMID: 31579831; PMCID: PMC6760171.
      View in: PubMed   Mentions: 3  
    46. Inhibition of de novo ceramide biosynthesis affects aging phenotype in an in vitro model of neuronal senescence. Aging (Albany NY). 2019 08 29; 11(16):6336-6357. Granzotto A, Bomba M, Castelli V, Navarra R, Massetti N, d'Aurora M, Onofrj M, Cicalini I, Del Boccio P, Gatta V, Cimini A, Piomelli D, Sensi SL. PMID: 31467258; PMCID: PMC6738398.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    47. Feeding Stimulates Sphingosine-1-Phosphate Mobilization in Mouse Hypothalamus. Int J Mol Sci. 2019 Aug 17; 20(16). Vozella V, Realini N, Misto A, Piomelli D. PMID: 31426457; PMCID: PMC6720287.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    48. Serum Endocannabinoid Levels in Patients With End-Stage Renal Disease. J Endocr Soc. 2019 Oct 01; 3(10):1869-1880. Moradi H, Park C, Igarashi M, Streja E, Argueta DA, Soohoo M, Daglian J, You AS, Rhee CM, Kashyap ML, DiPatrizio NV, Vaziri ND, Kalantar-Zadeh K, Piomelli D. PMID: 31583368; PMCID: PMC6767629.
      View in: PubMed   Mentions: 3  
    49. Fast and Sensitive Quantification of Δ9-Tetrahydrocannabinol and Its Main Oxidative Metabolites by Liquid Chromatography/Tandem Mass Spectrometry. Cannabis Cannabinoid Res. 2019; 4(2):110-123. Vozella V, Zibardi C, Ahmed F, Piomelli D. PMID: 31236476; PMCID: PMC6590723.
      View in: PubMed   Mentions: 5  
    50. Diurnal Profiles of N-Acylethanolamines in Goldfish Brain and Gastrointestinal Tract: Possible Role of Feeding. Front Neurosci. 2019; 13:450. Gómez-Boronat M, Isorna E, Armirotti A, Delgado MJ, Piomelli D, de Pedro N. PMID: 31133788; PMCID: PMC6514144.
      View in: PubMed   Mentions:
    51. Regulatory Barriers to Research on Cannabis and Cannabinoids: A Proposed Path Forward. Cannabis Cannabinoid Res. 2019 Mar; 4(1):21-32. Piomelli D, Solomon R, Abrams D, Balla A, Grant I, Marcotte T, Yoder J. PMID: 35236017; PMCID: PMC8884193.
      View in: PubMed   Mentions:
    52. Elevated plasma ceramide levels in post-menopausal women: a cross-sectional study. Aging (Albany NY). 2019 01 08; 11(1):73-88. Vozella V, Basit A, Piras F, Realini N, Armirotti A, Bossù P, Assogna F, Sensi SL, Spalletta G, Piomelli D. PMID: 30620722; PMCID: PMC6339790.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    53. Mast Cell-Derived Histamine Regulates Liver Ketogenesis via Oleoylethanolamide Signaling. Cell Metab. 2019 01 08; 29(1):91-102.e5. Misto A, Provensi G, Vozella V, Passani MB, Piomelli D. PMID: 30318340.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    54. Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proc Natl Acad Sci U S A. 2018 10 23; 115(43):E10032-E10040. Gorelik A, Gebai A, Illes K, Piomelli D, Nagar B. PMID: 30301806; PMCID: PMC6205464.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    55. Endocannabinoid Anandamide Mediates the Effect of Skeletal Muscle Sphingomyelins on Human Energy Expenditure. J Clin Endocrinol Metab. 2018 10 01; 103(10):3757-3766. Heinitz S, Basolo A, Piomelli D, Krakoff J, Piaggi P. PMID: 30113648; PMCID: PMC6179180.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    56. Effects of fatty acid amide hydrolase inhibitor URB597 in a rat model of trauma-induced long-term anxiety. Psychopharmacology (Berl). 2018 Nov; 235(11):3211-3221. Danandeh A, Vozella V, Lim J, Oveisi F, Ramirez GL, Mears D, Wynn G, Piomelli D. PMID: 30251159.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    57. Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit. J Med Chem. 2018 09 13; 61(17):7902-7916. Spadoni G, Bedini A, Furiassi L, Mari M, Mor M, Scalvini L, Lodola A, Ghidini A, Lucini V, Dugnani S, Scaglione F, Piomelli D, Jung KM, Supuran CT, Lucarini L, Durante M, Sgambellone S, Masini E, Rivara S. PMID: 30126274.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    58. Atypical Endocannabinoid Signaling Initiates a New Form of Memory-Related Plasticity at a Cortical Input to Hippocampus. Cereb Cortex. 2018 07 01; 28(7):2253-2266. Wang W, Jia Y, Pham DT, Palmer LC, Jung KM, Cox CD, Rumbaugh G, Piomelli D, Gall CM, Lynch G. PMID: 28520937; PMCID: PMC5998949.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    59. Author Correction: Patch clamp-assisted single neuron lipidomics. Sci Rep. 2018 Apr 25; 8(1):6772. Merrill CB, Basit A, Armirotti A, Jia Y, Gall CM, Lynch G, Piomelli D. PMID: 29691427; PMCID: PMC5915401.
      View in: PubMed   Mentions:    Fields:    
    60. Cannabis and the Opioid Crisis. Cannabis Cannabinoid Res. 2018; 3(1):108-116. Piomelli D, Weiss S, Boyd G, Pacula RL, Cooper Z. PMID: 29789812; PMCID: PMC5931647.
      View in: PubMed   Mentions: 3  
    61. Familial abnormalities of endocannabinoid signaling in schizophrenia. World J Biol Psychiatry. 2019 02; 20(2):117-125. Koethe D, Pahlisch F, Hellmich M, Rohleder C, Mueller JK, Meyer-Lindenberg A, Torrey EF, Piomelli D, Leweke FM. PMID: 29521179.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    62. Endocannabinoid System and Migraine Pain: An Update. Front Neurosci. 2018; 12:172. Greco R, Demartini C, Zanaboni AM, Piomelli D, Tassorelli C. PMID: 29615860; PMCID: PMC5867306.
      View in: PubMed   Mentions: 7  
    63. Peripheral Endocannabinoids Associated With Energy Expenditure in Native Americans of Southwestern Heritage. J Clin Endocrinol Metab. 2018 03 01; 103(3):1077-1087. Heinitz S, Basolo A, Piaggi P, Piomelli D, Jumpertz von Schwartzenberg R, Krakoff J. PMID: 29300902; PMCID: PMC6276675.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsCTClinical Trials
    64. Dual cyclooxygenase-fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site. J Biol Chem. 2018 03 02; 293(9):3028-3038. Goodman MC, Xu S, Rouzer CA, Banerjee S, Ghebreselasie K, Migliore M, Piomelli D, Marnett LJ. PMID: 29326169; PMCID: PMC5836124.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    65. Synthesis and characterization of the first inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD). Chem Commun (Camb). 2017 Nov 28; 53(95):12814-12817. Castellani B, Diamanti E, Pizzirani D, Tardia P, Maccesi M, Realini N, Magotti P, Garau G, Bakkum T, Rivara S, Mor M, Piomelli D. PMID: 29143042; PMCID: PMC5730275.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    66. Treating a novel plasticity defect rescues episodic memory in Fragile X model mice. Mol Psychiatry. 2018 08; 23(8):1798-1806. Wang W, Cox BM, Jia Y, Le AA, Cox CD, Jung KM, Hou B, Piomelli D, Gall CM, Lynch G. PMID: 29133950; PMCID: PMC5951717.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    67. The N-Acylethanolamine Acid Amidase Inhibitor ARN077 Suppresses Inflammation and Pruritus in a Mouse Model of Allergic Dermatitis. J Invest Dermatol. 2018 03; 138(3):562-569. Sasso O, Summa M, Armirotti A, Pontis S, De Mei C, Piomelli D. PMID: 29054595.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    68. Adolescent cannabinoid exposure effects on natural reward seeking and learning in rats. Psychopharmacology (Berl). 2018 01; 235(1):121-134. Schoch H, Huerta MY, Ruiz CM, Farrell MR, Jung KM, Huang JJ, Campbell RR, Piomelli D, Mahler SV. PMID: 29022083; PMCID: PMC5790819.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    69. Suppression of acute and anticipatory nausea by peripherally restricted fatty acid amide hydrolase inhibitor in animal models: role of PPARα and CB1 receptors. Br J Pharmacol. 2017 Nov; 174(21):3837-3847. Rock EM, Moreno-Sanz G, Limebeer CL, Petrie GN, Angelini R, Piomelli D, Parker LA. PMID: 28805944; PMCID: PMC5647182.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    70. Expert Panel on Understanding Cannabis: Medicine, Society, Government. Cannabis Cannabinoid Res. 2017; 2(1):247-251. Kazan K, Piomelli D, Rohrabacher D, Ajax L. PMID: 29082321; PMCID: PMC5657088.
      View in: PubMed   Mentions:
    71. Age-dependent changes in nervonic acid-containing sphingolipids in mouse hippocampus. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Dec; 1862(12):1502-1511. Vozella V, Basit A, Misto A, Piomelli D. PMID: 28855145.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    72. Novel activity-based probes for N-acylethanolamine acid amidase. Chem Commun (Camb). 2017 Aug 22; 53(86):11810-11813. Petracca R, Romeo E, Baggelaar MP, Artola M, Pontis S, Ponzano S, Overkleeft HS, van der Stelt M, Piomelli D. PMID: 29035406.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    73. Inhibition of monoacylglycerol lipase: Another signalling pathway for potential therapeutic targets in migraine? Cephalalgia. 2018 05; 38(6):1138-1147. Greco R, Demartini C, Zanaboni AM, Berliocchi L, Piomelli D, Tassorelli C. PMID: 28816506.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    74. Complete Acid Ceramidase ablation prevents cancer-initiating cell formation in melanoma cells. Sci Rep. 2017 08 07; 7(1):7411. Lai M, Realini N, La Ferla M, Passalacqua I, Matteoli G, Ganesan A, Pistello M, Mazzanti CM, Piomelli D. PMID: 28785021; PMCID: PMC5547127.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    75. Patch clamp-assisted single neuron lipidomics. Sci Rep. 2017 07 13; 7(1):5318. Merrill CB, Basit A, Armirotti A, Jia Y, Gall CM, Lynch G, Piomelli D. PMID: 28706218; PMCID: PMC5509708.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    76. Remote memories are enhanced by COMT activity through dysregulation of the endocannabinoid system in the prefrontal cortex. Mol Psychiatry. 2018 04; 23(4):1040-1050. Scheggia D, Zamberletti E, Realini N, Mereu M, Contarini G, Ferretti V, Managò F, Margiani G, Brunoro R, Rubino T, De Luca MA, Piomelli D, Parolaro D, Papaleo F. PMID: 28630452.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    77. Specific skeletal muscle sphingolipid compounds in energy expenditure regulation and weight gain in Native Americans of Southwestern heritage. Int J Obes (Lond). 2017 10; 41(10):1585-1593. Heinitz S, Piaggi P, Vinales KL, Basolo A, Spranger J, Piomelli D, Krakoff J, Jumpertz von Schwartzenberg R. PMID: 28607453; PMCID: PMC5626585.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    78. Identification of a Widespread Palmitoylethanolamide Contamination in Standard Laboratory Glassware. Cannabis Cannabinoid Res. 2017; 2(1):123-132. Angelini R, Argueta DA, Piomelli D, DiPatrizio NV. PMID: 28861512; PMCID: PMC5510777.
      View in: PubMed   Mentions: 6  
    79. A Guide to the National Academy of Science Report on Cannabis: An Exclusive Discussion with Panel Members. Cannabis Cannabinoid Res. 2017; 2(1):155-159. Piomelli D, Cooper Z, Abrams D, Grant I, Patel S. PMID: 28861515; PMCID: PMC5569624.
      View in: PubMed   Mentions: 1  
    80. Endocannabinoid Signaling in the Control of Social Behavior. Trends Neurosci. 2017 07; 40(7):385-396. Wei D, Allsop S, Tye K, Piomelli D. PMID: 28554687; PMCID: PMC5699224.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    81. Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities. Neuropharmacology. 2017 Sep 15; 124:3-12. Khurana L, Mackie K, Piomelli D, Kendall DA. PMID: 28527758; PMCID: PMC5540789.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    82. TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice. Nat Commun. 2017 05 10; 8:15292. Marrone MC, Morabito A, Giustizieri M, Chiurchiù V, Leuti A, Mattioli M, Marinelli S, Riganti L, Lombardi M, Murana E, Totaro A, Piomelli D, Ragozzino D, Oddi S, Maccarrone M, Verderio C, Marinelli S. PMID: 28489079; PMCID: PMC5436240.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    83. Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels. J Alzheimers Dis. 2017; 60(3):769-781. den Hoedt S, Janssen CIF, Astarita G, Piomelli D, Leijten FPJ, Crivelli SM, Verhoeven AJM, de Vries HE, Walter J, Martinez-Martinez P, Sijbrands EJG, Kiliaan AJ, Mulder MT. PMID: 28035926.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    84. Dysfunctional oleoylethanolamide signaling in a mouse model of Prader-Willi syndrome. Pharmacol Res. 2017 03; 117:75-81. Igarashi M, Narayanaswami V, Kimonis V, Galassetti PM, Oveisi F, Jung KM, Piomelli D. PMID: 28007570; PMCID: PMC5922435.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    85. Neurophysiology of space travel: energetic solar particles cause cell type-specific plasticity of neurotransmission. Brain Struct Funct. 2017 Jul; 222(5):2345-2357. Lee SH, Dudok B, Parihar VK, Jung KM, Zöldi M, Kang YJ, Maroso M, Alexander AL, Nelson GA, Piomelli D, Katona I, Limoli CL, Soltesz I. PMID: 27905022; PMCID: PMC5504243.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    86. Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase. J Vis Exp. 2016 11 23; (117). Romeo E, Pontis S, Ponzano S, Bonezzi F, Migliore M, Di Martino S, Summa M, Piomelli D. PMID: 27911411; PMCID: PMC5226263.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    87. Progress in the development of β-lactams as N-Acylethanolamine Acid Amidase (NAAA) inhibitors: Synthesis and SAR study of new, potent N-O-substituted derivatives. Eur J Med Chem. 2017 Jan 27; 126:561-575. Petracca R, Ponzano S, Bertozzi SM, Sasso O, Piomelli D, Bandiera T, Bertozzi F. PMID: 27915171.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    88. Bile Acid Recognition by NAPE-PLD. ACS Chem Biol. 2016 10 21; 11(10):2908-2914. Margheritis E, Castellani B, Magotti P, Peruzzi S, Romeo E, Natali F, Mostarda S, Gioiello A, Piomelli D, Garau G. PMID: 27571266; PMCID: PMC5074845.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    89. Increased Renal 2-Arachidonoylglycerol Level Is Associated with Improved Renal Function in a Mouse Model of Acute Kidney Injury. Cannabis Cannabinoid Res. 2016; 1(1):218-228. Moradi H, Oveisi F, Khanifar E, Moreno-Sanz G, Vaziri ND, Piomelli D. PMID: 28861493; PMCID: PMC5531066.
      View in: PubMed   Mentions: 7  
    90. A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation. eNeuro. 2016 Jul-Aug; 3(4). Wang W, Trieu BH, Palmer LC, Jia Y, Pham DT, Jung KM, Karsten CA, Merrill CB, Mackie K, Gall CM, Piomelli D, Lynch G. PMID: 27517090; PMCID: PMC4976302.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    91. Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL. Sci Rep. 2016 08 08; 6:31046. Scalvini L, Vacondio F, Bassi M, Pala D, Lodola A, Rivara S, Jung KM, Piomelli D, Mor M. PMID: 27499063; PMCID: PMC4976315.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    92. Endogenous N-acyl taurines regulate skin wound healing. Proc Natl Acad Sci U S A. 2016 07 26; 113(30):E4397-406. Sasso O, Pontis S, Armirotti A, Cardinali G, Kovacs D, Migliore M, Summa M, Moreno-Sanz G, Picardo M, Piomelli D. PMID: 27412859; PMCID: PMC4968764.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    93. Second-Generation Non-Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis. Angew Chem Int Ed Engl. 2016 09 05; 55(37):11193-11197. Migliore M, Pontis S, Fuentes de Arriba AL, Realini N, Torrente E, Armirotti A, Romeo E, Di Martino S, Russo D, Pizzirani D, Summa M, Lanfranco M, Ottonello G, Busquet P, Jung KM, Garcia-Guzman M, Heim R, Scarpelli R, Piomelli D. PMID: 27404798; PMCID: PMC5009002.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    94. Absolute nutrient concentration measurements in cell culture media: (1)H q-NMR spectra and data to compare the efficiency of pH-controlled protein precipitation versus CPMG or post-processing filtering approaches. Data Brief. 2016 Sep; 8:387-93. Goldoni L, Beringhelli T, Rocchia W, Realini N, Piomelli D. PMID: 27331118; PMCID: PMC4909824.
      View in: PubMed   Mentions:
    95. Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain. J Med Chem. 2016 03 24; 59(6):2612-32. Brindisi M, Maramai S, Gemma S, Brogi S, Grillo A, Di Cesare Mannelli L, Gabellieri E, Lamponi S, Saponara S, Gorelli B, Tedesco D, Bonfiglio T, Landry C, Jung KM, Armirotti A, Luongo L, Ligresti A, Piscitelli F, Bertucci C, Dehouck MP, Campiani G, Maione S, Ghelardini C, Pittaluga A, Piomelli D, Di Marzo V, Butini S. PMID: 26888301.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    96. A simple and accurate protocol for absolute polar metabolite quantification in cell cultures using quantitative nuclear magnetic resonance. Anal Biochem. 2016 May 15; 501:26-34. Goldoni L, Beringhelli T, Rocchia W, Realini N, Piomelli D. PMID: 26898303.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    97. Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR:LA-cp rat. J Lipid Res. 2016 Apr; 57(4):638-49. Jacome-Sosa M, Vacca C, Mangat R, Diane A, Nelson RC, Reaney MJ, Shen J, Curtis JM, Vine DF, Field CJ, Igarashi M, Piomelli D, Banni S, Proctor SD. PMID: 26891736; PMCID: PMC4808772.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    98. A role for the endocannabinoid 2-arachidonoyl-sn-glycerol for social and high-fat food reward in male mice. Psychopharmacology (Berl). 2016 05; 233(10):1911-9. Wei D, Lee D, Li D, Daglian J, Jung KM, Piomelli D. PMID: 26873082; PMCID: PMC5118226.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    99. Ion mobility mass spectrometry enhances low-abundance species detection in untargeted lipidomics. Metabolomics. 2016; 12:50. Basit A, Pontis S, Piomelli D, Armirotti A. PMID: 26900387; PMCID: PMC4744830.
      View in: PubMed   Mentions: 5     Fields:    
    100. Obesity development in neuron-specific lipoprotein lipase deficient mice is not responsive to increased dietary fat content or change in fat composition. Metabolism. 2016 07; 65(7):987-97. Wang H, Taussig MD, DiPatrizio NV, Bruce K, Piomelli D, Eckel RH. PMID: 27282869.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    101. Enhancement of Anandamide-Mediated Endocannabinoid Signaling Corrects Autism-Related Social Impairment. Cannabis Cannabinoid Res. 2016; 1(1):81-89. Wei D, Dinh D, Lee D, Li D, Anguren A, Moreno-Sanz G, Gall CM, Piomelli D. PMID: 28861483; PMCID: PMC5549436.
      View in: PubMed   Mentions: 23  
    102. Medicinal Cannabis in California: An Interview with Igor Grant, MD. Cannabis Cannabinoid Res. 2016; 1(1):78-80. Piomelli D, Grant I. PMID: 28861482; PMCID: PMC5576609.
      View in: PubMed   Mentions:
    103. Potent α-amino-β-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure-activity relationship (SAR) studies. Eur J Med Chem. 2016 Mar 23; 111:138-59. Nuzzi A, Fiasella A, Ortega JA, Pagliuca C, Ponzano S, Pizzirani D, Bertozzi SM, Ottonello G, Tarozzo G, Reggiani A, Bandiera T, Bertozzi F, Piomelli D. PMID: 26866968.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    104. An Important Role for N-Acylethanolamine Acid Amidase in the Complete Freund's Adjuvant Rat Model of Arthritis. J Pharmacol Exp Ther. 2016 Mar; 356(3):656-63. Bonezzi FT, Sasso O, Pontis S, Realini N, Romeo E, Ponzano S, Nuzzi A, Fiasella A, Bertozzi F, Piomelli D. PMID: 26769918.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    105. Assay of Monoacylglycerol Lipase Activity. Methods Mol Biol. 2016; 1412:157-68. Jung KM, Piomelli D. PMID: 27245902.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    106. Introduction to Cannabis and Cannabinoid Research. Cannabis Cannabinoid Res. 2016; 1(1):1-2. Piomelli D. PMID: 28861473; PMCID: PMC5576637.
      View in: PubMed   Mentions:
    107. The Cannabis sativa Versus Cannabis indica Debate: An Interview with Ethan Russo, MD. Cannabis Cannabinoid Res. 2016; 1(1):44-46. Piomelli D, Russo EB. PMID: 28861479; PMCID: PMC5576603.
      View in: PubMed   Mentions: 31  
    108. Legal or Illegal, Cannabis Is Still Addictive. Cannabis Cannabinoid Res. 2016; 1(1):47-53. Piomelli D, Haney M, Budney AJ, Piazza PV. PMID: 28861480; PMCID: PMC5576604.
      View in: PubMed   Mentions:
    109. Potent multitarget FAAH-COX inhibitors: Design and structure-activity relationship studies. Eur J Med Chem. 2016 Feb 15; 109:216-37. Migliore M, Habrant D, Sasso O, Albani C, Bertozzi SM, Armirotti A, Piomelli D, Scarpelli R. PMID: 26774927; PMCID: PMC4752335.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    110. Fluorine nuclear magnetic resonance-based assay in living mammalian cells. Anal Biochem. 2016 Feb 15; 495:52-9. Veronesi M, Giacomina F, Romeo E, Castellani B, Ottonello G, Lambruschini C, Garau G, Scarpelli R, Bandiera T, Piomelli D, Dalvit C. PMID: 26686030.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    111. P007. Inhibition of monoacylglycerol lipase activity modulates the activation of brain structures relevant for migraine pathogenesis. J Headache Pain. 2015 Dec; 16(Suppl 1):A165. Greco R, Bandiera T, Mangione AS, Demartini C, Nappi G, Sandrini G, Piomelli D, Tassorelli C. PMID: 28132223; PMCID: PMC4759149.
      View in: PubMed   Mentions:    Fields:    
    112. Benzoxazolone Carboxamides as Potent Acid Ceramidase Inhibitors: Synthesis and Structure-Activity Relationship (SAR) Studies. J Med Chem. 2015 Dec 10; 58(23):9258-72. Bach A, Pizzirani D, Realini N, Vozella V, Russo D, Penna I, Melzig L, Scarpelli R, Piomelli D. PMID: 26560855.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    113. Macrophage-derived lipid agonists of PPAR-α as intrinsic controllers of inflammation. Crit Rev Biochem Mol Biol. 2016; 51(1):7-14. Pontis S, Ribeiro A, Sasso O, Piomelli D. PMID: 26585314.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    114. Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats. Psychopharmacology (Berl). 2016 05; 233(10):1879-88. Panlilio LV, Thorndike EB, Nikas SP, Alapafuja SO, Bandiera T, Cravatt BF, Makriyannis A, Piomelli D, Goldberg SR, Justinova Z. PMID: 26558620; PMCID: PMC4846548.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    115. Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION. J Biol Chem. 2016 Jan 29; 291(5):2422-34. Realini N, Palese F, Pizzirani D, Pontis S, Basit A, Bach A, Ganesan A, Piomelli D. PMID: 26553872; PMCID: PMC4732224.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    116. Endocannabinoid signaling mediates oxytocin-driven social reward. Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45):14084-9. Wei D, Lee D, Cox CD, Karsten CA, Peñagarikano O, Geschwind DH, Gall CM, Piomelli D. PMID: 26504214; PMCID: PMC4653148.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    117. A Double Whammy: Targeting Both Fatty Acid Amide Hydrolase (FAAH) and Cyclooxygenase (COX) To Treat Pain and Inflammation. ChemMedChem. 2016 06 20; 11(12):1242-51. Scarpelli R, Sasso O, Piomelli D. PMID: 26486424; PMCID: PMC4840092.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    118. Endocannabinoid Modulation of Predator Stress-Induced Long-Term Anxiety in Rats. Neuropsychopharmacology. 2016 Apr; 41(5):1329-39. Lim J, Igarashi M, Jung KM, Butini S, Campiani G, Piomelli D. PMID: 26361059; PMCID: PMC4793117.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    119. Fasting stimulates 2-AG biosynthesis in the small intestine: role of cholinergic pathways. Am J Physiol Regul Integr Comp Physiol. 2015 Oct 15; 309(8):R805-13. DiPatrizio NV, Igarashi M, Narayanaswami V, Murray C, Gancayco J, Russell A, Jung KM, Piomelli D. PMID: 26290104; PMCID: PMC4666947.
      View in: PubMed   Mentions: 18  Translation:Animals
    120. Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice. PLoS One. 2015; 10(8):e0135113. Yu T, Taussig MD, DiPatrizio NV, Astarita G, Piomelli D, Bergman BC, Dell'Acqua ML, Eckel RH, Wang H. PMID: 26263173; PMCID: PMC4532501.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    121. Monoglyceride lipase: Structure and inhibitors. Chem Phys Lipids. 2016 May; 197:13-24. Scalvini L, Piomelli D, Mor M. PMID: 26216043; PMCID: PMC4728057.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    122. Activity-Based Probe for N-Acylethanolamine Acid Amidase. ACS Chem Biol. 2015 Sep 18; 10(9):2057-2064. Romeo E, Ponzano S, Armirotti A, Summa M, Bertozzi F, Garau G, Bandiera T, Piomelli D. PMID: 26102511; PMCID: PMC4575644.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    123. Role of the satiety factor oleoylethanolamide in alcoholism. Addict Biol. 2016 07; 21(4):859-72. Bilbao A, Serrano A, Cippitelli A, Pavón FJ, Giuffrida A, Suárez J, García-Marchena N, Baixeras E, Gómez de Heras R, Orio L, Alén F, Ciccocioppo R, Cravatt BF, Parsons LH, Piomelli D, Rodríguez de Fonseca F. PMID: 26037332; PMCID: PMC4668242.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    124. Feeding-induced oleoylethanolamide mobilization is disrupted in the gut of diet-induced obese rodents. Biochim Biophys Acta. 2015 Sep; 1851(9):1218-26. Igarashi M, DiPatrizio NV, Narayanaswami V, Piomelli D. PMID: 26024927; PMCID: PMC4516666.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    125. Peroxide-Dependent MGL Sulfenylation Regulates 2-AG-Mediated Endocannabinoid Signaling in Brain Neurons. Chem Biol. 2015 May 21; 22(5):619-28. Dotsey EY, Jung KM, Basit A, Wei D, Daglian J, Vacondio F, Armirotti A, Mor M, Piomelli D. PMID: 26000748; PMCID: PMC4459529.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    126. Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice. J Physiol. 2015 Jun 01; 593(11):2527-45. Niki M, Jyotaki M, Yoshida R, Yasumatsu K, Shigemura N, DiPatrizio NV, Piomelli D, Ninomiya Y. PMID: 25728242; PMCID: PMC4461413.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    127. A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation. ACS Chem Biol. 2015 Aug 21; 10(8):1838-46. Ribeiro A, Pontis S, Mengatto L, Armirotti A, Chiurchiù V, Capurro V, Fiasella A, Nuzzi A, Romeo E, Moreno-Sanz G, Maccarrone M, Reggiani A, Tarzia G, Mor M, Bertozzi F, Bandiera T, Piomelli D. PMID: 25874594; PMCID: PMC4546552.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    128. Peripheral FAAH and soluble epoxide hydrolase inhibitors are synergistically antinociceptive. Pharmacol Res. 2015 Jul; 97:7-15. Sasso O, Wagner K, Morisseau C, Inceoglu B, Hammock BD, Piomelli D. PMID: 25882247; PMCID: PMC4464910.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    129. Effects of Fatty Acid Amide Hydrolase (FAAH) Inhibitors in Non-Human Primate Models of Nicotine Reward and Relapse. Neuropsychopharmacology. 2015 Aug; 40(9):2185-97. Justinova Z, Panlilio LV, Moreno-Sanz G, Redhi GH, Auber A, Secci ME, Mascia P, Bandiera T, Armirotti A, Bertorelli R, Chefer SI, Barnes C, Yasar S, Piomelli D, Goldberg SR. PMID: 25754762; PMCID: PMC4613608.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    130. Multitarget fatty acid amide hydrolase/cyclooxygenase blockade suppresses intestinal inflammation and protects against nonsteroidal anti-inflammatory drug-dependent gastrointestinal damage. FASEB J. 2015 Jun; 29(6):2616-27. Sasso O, Migliore M, Habrant D, Armirotti A, Albani C, Summa M, Moreno-Sanz G, Scarpelli R, Piomelli D. PMID: 25757568; PMCID: PMC4447230.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    131. Rapid evaluation of 25 key sphingolipids and phosphosphingolipids in human plasma by LC-MS/MS. Anal Bioanal Chem. 2015 Jul; 407(17):5189-98. Basit A, Piomelli D, Armirotti A. PMID: 25749796; PMCID: PMC4471391.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    132. Structure of human N-acylphosphatidylethanolamine-hydrolyzing phospholipase D: regulation of fatty acid ethanolamide biosynthesis by bile acids. Structure. 2015 Mar 03; 23(3):598-604. Magotti P, Bauer I, Igarashi M, Babagoli M, Marotta R, Piomelli D, Garau G. PMID: 25684574; PMCID: PMC4351732.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    133. Methamphetamine accelerates cellular senescence through stimulation of de novo ceramide biosynthesis. PLoS One. 2015; 10(2):e0116961. Astarita G, Avanesian A, Grimaldi B, Realini N, Justinova Z, Panlilio LV, Basit A, Goldberg SR, Piomelli D. PMID: 25671639; PMCID: PMC4324822.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    134. Intestinal lipid-derived signals that sense dietary fat. J Clin Invest. 2015 Mar 02; 125(3):891-8. DiPatrizio NV, Piomelli D. PMID: 25642767; PMCID: PMC4362267.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    135. Effects of peripheral FAAH blockade on NTG-induced hyperalgesia--evaluation of URB937 in an animal model of migraine. Cephalalgia. 2015 Oct; 35(12):1065-76. Greco R, Bandiera T, Mangione AS, Demartini C, Siani F, Nappi G, Sandrini G, Guijarro A, Armirotti A, Piomelli D, Tassorelli C. PMID: 25608877.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    136. Synthesis, biological evaluation, and 3D QSAR study of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters as N-acylethanolamine acid amidase (NAAA) inhibitors. J Med Chem. 2014 Dec 11; 57(23):10101-11. Ponzano S, Berteotti A, Petracca R, Vitale R, Mengatto L, Bandiera T, Cavalli A, Piomelli D, Bertozzi F, Bottegoni G. PMID: 25380517.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    137. Benzoxazolone carboxamides: potent and systemically active inhibitors of intracellular acid ceramidase. Angew Chem Int Ed Engl. 2015 Jan 07; 54(2):485-9. Pizzirani D, Bach A, Realini N, Armirotti A, Mengatto L, Bauer I, Girotto S, Pagliuca C, De Vivo M, Summa M, Ribeiro A, Piomelli D. PMID: 25395373; PMCID: PMC4502975.
      View in: PubMed   Mentions: 10     Fields:    
    138. A lipid gate for the peripheral control of pain. J Neurosci. 2014 Nov 12; 34(46):15184-91. Piomelli D, Hohmann AG, Seybold V, Hammock BD. PMID: 25392487; PMCID: PMC4228127.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    139. O-(triazolyl)methyl carbamates as a novel and potent class of fatty acid amide hydrolase (FAAH) inhibitors. ChemMedChem. 2015 Feb; 10(2):380-95. Colombano G, Albani C, Ottonello G, Ribeiro A, Scarpelli R, Tarozzo G, Daglian J, Jung KM, Piomelli D, Bandiera T. PMID: 25338703; PMCID: PMC4384654.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    140. Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain. Pharmacol Res. 2014 Sep; 87:87-93. Moreno-Sanz G, Barrera B, Armirotti A, Bertozzi SM, Scarpelli R, Bandiera T, Prieto JG, Duranti A, Tarzia G, Merino G, Piomelli D. PMID: 24993496; PMCID: PMC4134960.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    141. Role of oleoylethanolamide as a feeding regulator in goldfish. J Exp Biol. 2014 Aug 01; 217(Pt 15):2761-9. Tinoco AB, Armirotti A, Isorna E, Delgado MJ, Piomelli D, de Pedro N. PMID: 24855680.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    142. Applying a multitarget rational drug design strategy: the first set of modulators with potent and balanced activity toward dopamine D3 receptor and fatty acid amide hydrolase. Chem Commun (Camb). 2014 May 18; 50(38):4904-7. De Simone A, Ruda GF, Albani C, Tarozzo G, Bandiera T, Piomelli D, Cavalli A, Bottegoni G. PMID: 24691497; PMCID: PMC4038168.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    143. 3-Aminoazetidin-2-one derivatives as N-acylethanolamine acid amidase (NAAA) inhibitors suitable for systemic administration. ChemMedChem. 2014 Jul; 9(7):1602-14. Fiasella A, Nuzzi A, Summa M, Armirotti A, Tarozzo G, Tarzia G, Mor M, Bertozzi F, Bandiera T, Piomelli D. PMID: 24828120; PMCID: PMC4224963.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    144. Cannabinoid type 1 receptor availability in the amygdala mediates threat processing in trauma survivors. Neuropsychopharmacology. 2014 Oct; 39(11):2519-28. Pietrzak RH, Huang Y, Corsi-Travali S, Zheng MQ, Lin SF, Henry S, Potenza MN, Piomelli D, Carson RE, Neumeister A. PMID: 24820537; PMCID: PMC4207337.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    145. Advances in the discovery of N-acylethanolamine acid amidase inhibitors. Pharmacol Res. 2014 Aug; 86:11-7. Bandiera T, Ponzano S, Piomelli D. PMID: 24798679; PMCID: PMC4117721.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    146. A mighty (ochondrial) fight? Mol Metab. 2014 Jul; 3(4):345-6. Piomelli D. PMID: 24944892; PMCID: PMC4060220.
      View in: PubMed   Mentions: 3     Fields:    
    147. Sample preparation and orthogonal chromatography for broad polarity range plasma metabolomics: application to human subjects with neurodegenerative dementia. Anal Biochem. 2014 Jun 15; 455:48-54. Armirotti A, Basit A, Realini N, Caltagirone C, Bossù P, Spalletta G, Piomelli D. PMID: 24708938.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    148. Peripheral gating of pain signals by endogenous lipid mediators. Nat Neurosci. 2014 Feb; 17(2):164-74. Piomelli D, Sasso O. PMID: 24473264; PMCID: PMC4020413.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    149. A discount on cannabinoids. Biol Psychiatry. 2014 Mar 15; 75(6):432-4. Piomelli D. PMID: 24560432.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    150. Circadian control of fatty acid elongation by SIRT1 protein-mediated deacetylation of acetyl-coenzyme A synthetase 1. J Biol Chem. 2014 Feb 28; 289(9):6091-7. Sahar S, Masubuchi S, Eckel-Mahan K, Vollmer S, Galla L, Ceglia N, Masri S, Barth TK, Grimaldi B, Oluyemi O, Astarita G, Hallows WC, Piomelli D, Imhof A, Baldi P, Denu JM, Sassone-Corsi P. PMID: 24425865; PMCID: PMC3937675.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    151. Synthesis, structure-activity, and structure-stability relationships of 2-substituted-N-(4-oxo-3-oxetanyl) N-acylethanolamine acid amidase (NAAA) inhibitors. ChemMedChem. 2014 Feb; 9(2):323-36. Vitale R, Ottonello G, Petracca R, Bertozzi SM, Ponzano S, Armirotti A, Berteotti A, Dionisi M, Cavalli A, Piomelli D, Bandiera T, Bertozzi F. PMID: 24403170.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    152. Effects of acute stress on cardiac endocannabinoids, lipogenesis, and inflammation in rats. Psychosom Med. 2014 Jan; 76(1):20-28. Holman EA, Guijarro A, Lim J, Piomelli D. PMID: 24367128; PMCID: PMC3988664.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    153. Fluorine NMR-based screening on cell membrane extracts. ChemMedChem. 2014 Feb; 9(2):286-9. Veronesi M, Romeo E, Lambruschini C, Piomelli D, Bandiera T, Scarpelli R, Garau G, Dalvit C. PMID: 24339446.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    154. A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity. ACS Chem Biol. 2014 Feb 21; 9(2):398-404. Iorio M, Sasso O, Maffioli SI, Bertorelli R, Monciardini P, Sosio M, Bonezzi F, Summa M, Brunati C, Bordoni R, Corti G, Tarozzo G, Piomelli D, Reggiani A, Donadio S. PMID: 24191663.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    155. Anandamide transport inhibition by ARN272 attenuates nausea-induced behaviour in rats, and vomiting in shrews (Suncus murinus). Br J Pharmacol. 2013 Nov; 170(5):1130-6. O'Brien LD, Limebeer CL, Rock EM, Bottegoni G, Piomelli D, Parker LA. PMID: 23991698; PMCID: PMC3949659.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    156. Brown adipose tissue quantification in human neonates using water-fat separated MRI. PLoS One. 2013; 8(10):e77907. Rasmussen JM, Entringer S, Nguyen A, van Erp TG, Burns J, Guijarro A, Oveisi F, Swanson JM, Piomelli D, Wadhwa PD, Buss C, Potkin SG. PMID: 24205024; PMCID: PMC3813555.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    157. Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease. Hum Mol Genet. 2014 Mar 01; 23(5):1333-44. Llewellyn KJ, Nalbandian A, Jung KM, Nguyen C, Avanesian A, Mozaffar T, Piomelli D, Kimonis VE. PMID: 24158850; PMCID: PMC3919004.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    158. Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors. J Med Chem. 2013 Sep 12; 56(17):6917-34. Ponzano S, Bertozzi F, Mengatto L, Dionisi M, Armirotti A, Romeo E, Berteotti A, Fiorelli C, Tarozzo G, Reggiani A, Duranti A, Tarzia G, Mor M, Cavalli A, Piomelli D, Bandiera T. PMID: 23991897.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    159. More surprises lying ahead. The endocannabinoids keep us guessing. Neuropharmacology. 2014 Jan; 76 Pt B:228-34. Piomelli D. PMID: 23954677; PMCID: PMC3855347.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimals
    160. Development of fragment-based n-FABS NMR screening applied to the membrane enzyme FAAH. Chembiochem. 2013 Sep 02; 14(13):1611-9. Lambruschini C, Veronesi M, Romeo E, Garau G, Bandiera T, Piomelli D, Scarpelli R, Dalvit C. PMID: 23918626.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    161. Synthesis and structure-activity relationship studies of O-biphenyl-3-yl carbamates as peripherally restricted fatty acid amide hydrolase inhibitors. J Med Chem. 2013 Jul 25; 56(14):5917-30. Moreno-Sanz G, Duranti A, Melzig L, Fiorelli C, Ruda GF, Colombano G, Mestichelli P, Sanchini S, Tontini A, Mor M, Bandiera T, Scarpelli R, Tarzia G, Piomelli D. PMID: 23822179; PMCID: PMC4062305.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    162. Elevated brain cannabinoid CB1 receptor availability in post-traumatic stress disorder: a positron emission tomography study. Mol Psychiatry. 2013 Sep; 18(9):1034-40. Neumeister A, Normandin MD, Pietrzak RH, Piomelli D, Zheng MQ, Gujarro-Anton A, Potenza MN, Bailey CR, Lin SF, Najafzadeh S, Ropchan J, Henry S, Corsi-Travali S, Carson RE, Huang Y. PMID: 23670490; PMCID: PMC3752332.
      View in: PubMed   Mentions: 111     Fields:    Translation:Humans
    163. Discovery of a new class of highly potent inhibitors of acid ceramidase: synthesis and structure-activity relationship (SAR). J Med Chem. 2013 May 09; 56(9):3518-30. Pizzirani D, Pagliuca C, Realini N, Branduardi D, Bottegoni G, Mor M, Bertozzi F, Scarpelli R, Piomelli D, Bandiera T. PMID: 23614460.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    164. A fatty gut feeling. Trends Endocrinol Metab. 2013 Jul; 24(7):332-41. Piomelli D. PMID: 23567058; PMCID: PMC3778443.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    165. Quantum mechanics/molecular mechanics modeling of fatty acid amide hydrolase reactivation distinguishes substrate from irreversible covalent inhibitors. J Med Chem. 2013 Mar 28; 56(6):2500-12. Lodola A, Capoferri L, Rivara S, Tarzia G, Piomelli D, Mulholland A, Mor M. PMID: 23425199; PMCID: PMC3724458.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    166. Endocannabinoid signaling in the gut mediates preference for dietary unsaturated fats. FASEB J. 2013 Jun; 27(6):2513-20. DiPatrizio NV, Joslin A, Jung KM, Piomelli D. PMID: 23463697; PMCID: PMC3659363.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    167. Pharmacological characterization of memoquin, a multi-target compound for the treatment of Alzheimer's disease. PLoS One. 2013; 8(2):e56870. Capurro V, Busquet P, Lopes JP, Bertorelli R, Tarozzo G, Bolognesi ML, Piomelli D, Reggiani A, Cavalli A. PMID: 23441223; PMCID: PMC3575497.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    168. Wagging the Tail: Essential Role of Substrate Flexibility in FAAH Catalysis. J Chem Theory Comput. 2013 Feb 12; 9(2):1202-13. Palermo G, Campomanes P, Neri M, Piomelli D, Cavalli A, Rothlisberger U, De Vivo M. PMID: 26588763.
      View in: PubMed   Mentions: 8     Fields:    
    169. Galantamine potentiates the neuroprotective effect of memantine against NMDA-induced excitotoxicity. Brain Behav. 2013 Mar; 3(2):67-74. Lopes JP, Tarozzo G, Reggiani A, Piomelli D, Cavalli A. PMID: 23532860; PMCID: PMC3607148.
      View in: PubMed   Mentions: 10     Fields:    
    170. Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity. Sci Rep. 2013; 3:1035. Realini N, Solorzano C, Pagliuca C, Pizzirani D, Armirotti A, Luciani R, Costi MP, Bandiera T, Piomelli D. PMID: 23301156; PMCID: PMC3539145.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    171. A binding site for nonsteroidal anti-inflammatory drugs in fatty acid amide hydrolase. J Am Chem Soc. 2013 Jan 09; 135(1):22-5. Bertolacci L, Romeo E, Veronesi M, Magotti P, Albani C, Dionisi M, Lambruschini C, Scarpelli R, Cavalli A, De Vivo M, Piomelli D, Garau G. PMID: 23240907; PMCID: PMC3562592.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    172. Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier. Br J Pharmacol. 2012 Dec; 167(8):1620-8. Moreno-Sanz G, Sasso O, Guijarro A, Oluyemi O, Bertorelli R, Reggiani A, Piomelli D. PMID: 22774772; PMCID: PMC3525865.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    173. Synergistic effects of galantamine and memantine in attenuating scopolamine-induced amnesia in mice. J Pharmacol Sci. 2012; 120(4):305-9. Busquet P, Capurro V, Cavalli A, Piomelli D, Reggiani A, Bertorelli R. PMID: 23149577.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    174. Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models. Pain. 2013 Mar; 154(3):350-360. Sasso O, Moreno-Sanz G, Martucci C, Realini N, Dionisi M, Mengatto L, Duranti A, Tarozzo G, Tarzia G, Mor M, Bertorelli R, Reggiani A, Piomelli D. PMID: 23218523; PMCID: PMC3723234.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    175. Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer's disease. J Med Chem. 2012 Nov 26; 55(22):9708-21. Simoni E, Daniele S, Bottegoni G, Pizzirani D, Trincavelli ML, Goldoni L, Tarozzo G, Reggiani A, Martini C, Piomelli D, Melchiorre C, Rosini M, Cavalli A. PMID: 23033965.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    176. Identification and characterization of carprofen as a multitarget fatty acid amide hydrolase/cyclooxygenase inhibitor. J Med Chem. 2012 Oct 25; 55(20):8807-26. Favia AD, Habrant D, Scarpelli R, Migliore M, Albani C, Bertozzi SM, Dionisi M, Tarozzo G, Piomelli D, Cavalli A, De Vivo M. PMID: 23043222; PMCID: PMC3764917.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    177. Peroxisome proliferator-activated receptor α mediates acute effects of palmitoylethanolamide on sensory neurons. J Neurosci. 2012 Sep 12; 32(37):12735-43. Khasabova IA, Xiong Y, Coicou LG, Piomelli D, Seybold V. PMID: 22972997; PMCID: PMC3462371.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    178. Associations of fatty acids in cerebrospinal fluid with peripheral glucose concentrations and energy metabolism. PLoS One. 2012; 7(7):e41503. Jumpertz R, Guijarro A, Pratley RE, Mason CC, Piomelli D, Krakoff J. PMID: 22911803; PMCID: PMC3404019.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    179. Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats. Pediatr Res. 2012 Oct; 72(4):400-6. Carloni S, Alonso-Alconada D, Girelli S, Duranti A, Tontini A, Piomelli D, Hilario E, Alvarez A, Balduini W. PMID: 22821058.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    180. Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia. J Neurosci. 2012 Jul 11; 32(28):9457-68. Gregg LC, Jung KM, Spradley JM, Nyilas R, Suplita RL, Zimmer A, Watanabe M, Mackie K, Katona I, Piomelli D, Hohmann AG. PMID: 22787031; PMCID: PMC3652685.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    181. Selective cannabinoid-1 receptor blockade benefits fatty acid and triglyceride metabolism significantly in weight-stable nonhuman primates. Am J Physiol Endocrinol Metab. 2012 Sep 01; 303(5):E624-34. Vaidyanathan V, Bastarrachea RA, Higgins PB, Voruganti VS, Kamath S, DiPatrizio NV, Piomelli D, Comuzzie AG, Parks EJ. PMID: 22761159; PMCID: PMC3468508.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    182. The thrifty lipids: endocannabinoids and the neural control of energy conservation. Trends Neurosci. 2012 Jul; 35(7):403-11. DiPatrizio NV, Piomelli D. PMID: 22622030; PMCID: PMC3744874.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimals
    183. N-(2-oxo-3-oxetanyl)carbamic acid esters as N-acylethanolamine acid amidase inhibitors: synthesis and structure-activity and structure-property relationships. J Med Chem. 2012 May 24; 55(10):4824-36. Duranti A, Tontini A, Antonietti F, Vacondio F, Fioni A, Silva C, Lodola A, Rivara S, Solorzano C, Piomelli D, Tarzia G, Mor M. PMID: 22515328.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    184. β-Lactones Inhibit N-acylethanolamine Acid Amidase by S-Acylation of the Catalytic N-Terminal Cysteine. ACS Med Chem Lett. 2012 May 10; 3(5):422-6. Armirotti A, Romeo E, Ponzano S, Mengatto L, Dionisi M, Karacsonyi C, Bertozzi F, Garau G, Tarozzo G, Reggiani A, Bandiera T, Tarzia G, Mor M, Piomelli D. PMID: 24900487; PMCID: PMC4025845.
      View in: PubMed   Mentions: 11  
    185. Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. Transl Psychiatry. 2012 Mar 20; 2:e94. Leweke FM, Piomelli D, Pahlisch F, Muhl D, Gerth CW, Hoyer C, Klosterkötter J, Hellmich M, Koethe D. PMID: 22832859; PMCID: PMC3316151.
      View in: PubMed   Mentions: 260     Fields:    Translation:HumansCellsCTClinical Trials
    186. 2-arachidonoylglycerol signaling in forebrain regulates systemic energy metabolism. Cell Metab. 2012 Mar 07; 15(3):299-310. Jung KM, Clapper JR, Fu J, D'Agostino G, Guijarro A, Thongkham D, Avanesian A, Astarita G, DiPatrizio NV, Frontini A, Cinti S, Diano S, Piomelli D. PMID: 22405068; PMCID: PMC3729112.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    187. Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions. Pharmacol Res. 2012 May; 65(5):553-63. Sasso O, Bertorelli R, Bandiera T, Scarpelli R, Colombano G, Armirotti A, Moreno-Sanz G, Reggiani A, Piomelli D. PMID: 22420940; PMCID: PMC3738192.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    188. A catalytic mechanism for cysteine N-terminal nucleophile hydrolases, as revealed by free energy simulations. PLoS One. 2012; 7(2):e32397. Lodola A, Branduardi D, De Vivo M, Capoferri L, Mor M, Piomelli D, Cavalli A. PMID: 22389698; PMCID: PMC3289653.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    189. Decreased body weight and hepatic steatosis with altered fatty acid ethanolamide metabolism in aged L-Fabp -/- mice. J Lipid Res. 2012 Apr; 53(4):744-54. Newberry EP, Kennedy SM, Xie Y, Luo J, Crooke RM, Graham MJ, Fu J, Piomelli D, Davidson NO. PMID: 22327204; PMCID: PMC3307651.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    190. Moving beyond "good fat, bad fat": the complex roles of dietary lipids in cellular function and health: session abstracts. Adv Nutr. 2012 Jan; 3(1):60-8. Abumrad NA, Piomelli D, Yurko-Mauro K, Merrill A, Clandinin MT, Serhan CN. PMID: 22332103; PMCID: PMC3262616.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    191. Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. Nat Commun. 2012; 3:1080. Jung KM, Sepers M, Henstridge CM, Lassalle O, Neuhofer D, Martin H, Ginger M, Frick A, DiPatrizio NV, Mackie K, Katona I, Piomelli D, Manzoni OJ. PMID: 23011134; PMCID: PMC3657999.
      View in: PubMed   Mentions: 93     Fields:    Translation:AnimalsCells
    192. Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain. Neuroscience. 2012 Jan 27; 202:326-33. Snigdha S, Astarita G, Piomelli D, Cotman CW. PMID: 22183056; PMCID: PMC3447971.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    193. Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. PLoS One. 2011; 6(11):e28142. Cippitelli A, Astarita G, Duranti A, Caprioli G, Ubaldi M, Stopponi S, Kallupi M, Sagratini G, Rodrìguez de Fonseca F, Piomelli D, Ciccocioppo R. PMID: 22140525; PMCID: PMC3227620.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    194. A catalytically silent FAAH-1 variant drives anandamide transport in neurons. Nat Neurosci. 2011 Nov 20; 15(1):64-9. Fu J, Bottegoni G, Sasso O, Bertorelli R, Rocchia W, Masetti M, Guijarro A, Lodola A, Armirotti A, Garau G, Bandiera T, Reggiani A, Mor M, Cavalli A, Piomelli D. PMID: 22101642; PMCID: PMC3245783.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    195. Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease. PLoS One. 2011; 6(10):e24777. Astarita G, Jung KM, Vasilevko V, Dipatrizio NV, Martin SK, Cribbs DH, Head E, Cotman CW, Piomelli D. PMID: 22046234; PMCID: PMC3202527.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    196. A thickening network of lipids. Pain. 2012 Jan; 153(1):3-4. Piomelli D. PMID: 22019134.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    197. Dietary and behavioral interventions protect against age related activation of caspase cascades in the canine brain. PLoS One. 2011; 6(9):e24652. Snigdha S, Berchtold N, Astarita G, Saing T, Piomelli D, Cotman CW. PMID: 21931796; PMCID: PMC3172245.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    198. Covalent inhibitors of fatty acid amide hydrolase: a rationale for the activity of piperidine and piperazine aryl ureas. J Med Chem. 2011 Oct 13; 54(19):6612-23. Palermo G, Branduardi D, Masetti M, Lodola A, Mor M, Piomelli D, Cavalli A, De Vivo M. PMID: 21830831; PMCID: PMC3774108.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    199. Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. Br J Pharmacol. 2011 Aug; 163(7):1464-78. Guindon J, Guijarro A, Piomelli D, Hohmann AG. PMID: 21198549; PMCID: PMC3165956.
      View in: PubMed   Mentions: 51     Fields:    Translation:Animals
    200. Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: steric effects of N-alkyl chain on rat plasma and liver stability. Eur J Med Chem. 2011 Sep; 46(9):4466-73. Vacondio F, Silva C, Lodola A, Carmi C, Rivara S, Duranti A, Tontini A, Sanchini S, Clapper JR, Piomelli D, Tarzia G, Mor M. PMID: 21820769; PMCID: PMC3714604.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    201. Decoding functional metabolomics with docosahexaenoyl ethanolamide (DHEA) identifies novel bioactive signals. J Biol Chem. 2011 Sep 09; 286(36):31532-41. Yang R, Fredman G, Krishnamoorthy S, Agrawal N, Irimia D, Piomelli D, Serhan CN. PMID: 21757729; PMCID: PMC3173121.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    202. The ABC membrane transporter ABCG2 prevents access of FAAH inhibitor URB937 to the central nervous system. Pharmacol Res. 2011 Oct; 64(4):359-63. Moreno-Sanz G, Barrera B, Guijarro A, d'Elia I, Otero JA, Alvarez AI, Bandiera T, Merino G, Piomelli D. PMID: 21767647; PMCID: PMC3729352.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    203. Endocannabinoid signal in the gut controls dietary fat intake. Proc Natl Acad Sci U S A. 2011 Aug 02; 108(31):12904-8. DiPatrizio NV, Astarita G, Schwartz G, Li X, Piomelli D. PMID: 21730161; PMCID: PMC3150876.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    204. Towards a whole-body systems [multi-organ] lipidomics in Alzheimer's disease. Prostaglandins Leukot Essent Fatty Acids. 2011 Nov; 85(5):197-203. Astarita G, Piomelli D. PMID: 21543199; PMCID: PMC3161165.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    205. An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease. Neurobiol Aging. 2012 Aug; 33(8):1522-32. Jung KM, Astarita G, Yasar S, Vasilevko V, Cribbs DH, Head E, Cotman CW, Piomelli D. PMID: 21546126; PMCID: PMC3154439.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    206. Diacylglycerol lipase-alpha and -beta control neurite outgrowth in neuro-2a cells through distinct molecular mechanisms. Mol Pharmacol. 2011 Jul; 80(1):60-7. Jung KM, Astarita G, Thongkham D, Piomelli D. PMID: 21493725; PMCID: PMC3127538.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    207. Sympathetic activity controls fat-induced oleoylethanolamide signaling in small intestine. J Neurosci. 2011 Apr 13; 31(15):5730-6. Fu J, Dipatrizio NV, Guijarro A, Schwartz GJ, Li X, Gaetani S, Astarita G, Piomelli D. PMID: 21490214; PMCID: PMC3084524.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    208. The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease. Mucosal Immunol. 2011 Sep; 4(5):574-83. Di Sabatino A, Battista N, Biancheri P, Rapino C, Rovedatti L, Astarita G, Vanoli A, Dainese E, Guerci M, Piomelli D, Pender SL, MacDonald TT, Maccarrone M, Corazza GR. PMID: 21471961.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    209. Blockade of nicotine reward and reinstatement by activation of alpha-type peroxisome proliferator-activated receptors. Biol Psychiatry. 2011 Apr 01; 69(7):633-41. Mascia P, Pistis M, Justinova Z, Panlilio LV, Luchicchi A, Lecca S, Scherma M, Fratta W, Fadda P, Barnes C, Redhi GH, Yasar S, Le Foll B, Tanda G, Piomelli D, Goldberg SR. PMID: 20801430; PMCID: PMC2994947.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    210. Plasma lipidomics reveals potential prognostic signatures within a cohort of cystic fibrosis patients. J Lipid Res. 2011 May; 52(5):1011-22. Ollero M, Astarita G, Guerrera IC, Sermet-Gaudelus I, Trudel S, Piomelli D, Edelman A. PMID: 21335323; PMCID: PMC3073467.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    211. Understanding the role of carbamate reactivity in fatty acid amide hydrolase inhibition by QM/MM mechanistic modelling. Chem Commun (Camb). 2011 Mar 07; 47(9):2517-9. Lodola A, Capoferri L, Rivara S, Chudyk E, Sirirak J, Dyguda-Kazimierowicz E, Andrzej Sokalski W, Mileni M, Tarzia G, Piomelli D, Mor M, Mulholland AJ. PMID: 21240393.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    212. Proinflammatory stimuli control N-acylphosphatidylethanolamine-specific phospholipase D expression in macrophages. Mol Pharmacol. 2011 Apr; 79(4):786-92. Zhu C, Solorzano C, Sahar S, Realini N, Fung E, Sassone-Corsi P, Piomelli D. PMID: 21233218; PMCID: PMC3063731.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    213. Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity. Cell Metab. 2011 Jan 05; 13(1):105-13. Wang H, Astarita G, Taussig MD, Bharadwaj KG, DiPatrizio NV, Nave KA, Piomelli D, Goldberg IJ, Eckel RH. PMID: 21195353; PMCID: PMC3034302.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    214. New lipidomic approaches in cystic fibrosis. Methods Mol Biol. 2011; 742:265-78. Ollero M, Guerrera IC, Astarita G, Piomelli D, Edelman A. PMID: 21547738.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    215. Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure. J Clin Endocrinol Metab. 2011 Mar; 96(3):787-91. Jumpertz R, Guijarro A, Pratley RE, Piomelli D, Krakoff J. PMID: 21177788; PMCID: PMC3047230.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    216. PER2 controls lipid metabolism by direct regulation of PPARγ. Cell Metab. 2010 Nov 03; 12(5):509-20. Grimaldi B, Bellet MM, Katada S, Astarita G, Hirayama J, Amin RH, Granneman JG, Piomelli D, Leff T, Sassone-Corsi P. PMID: 21035761; PMCID: PMC4103168.
      View in: PubMed   Mentions: 154     Fields:    Translation:AnimalsCells
    217. Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice. Psychopharmacology (Berl). 2011 Mar; 214(2):465-76. Cassano T, Gaetani S, Macheda T, Laconca L, Romano A, Morgese MG, Cimmino CS, Chiarotti F, Bambico FR, Gobbi G, Cuomo V, Piomelli D. PMID: 21042794; PMCID: PMC3045513.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    218. Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus. Neuroscience. 2011 Feb 03; 174:50-63. Ludányi A, Hu SS, Yamazaki M, Tanimura A, Piomelli D, Watanabe M, Kano M, Sakimura K, Maglóczky Z, Mackie K, Freund TF, Katona I. PMID: 21035522; PMCID: PMC3678284.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    219. Ten years of Nature Reviews Neuroscience: insights from the highly cited. Nat Rev Neurosci. 2010 10; 11(10):718-26. Luo L, Rodriguez E, Jerbi K, Lachaux JP, Martinerie J, Corbetta M, Shulman GL, Piomelli D, Turrigiano GG, Nelson SB, Joëls M, de Kloet ER, Holsboer F, Amodio DM, Frith CD, Block ML, Zecca L, Hong JS, Dantzer R, Kelley KW, Craig AD. PMID: 20852655; PMCID: PMC3395239.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    220. Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism. Nat Neurosci. 2010 Oct; 13(10):1265-70. Clapper JR, Moreno-Sanz G, Russo R, Guijarro A, Vacondio F, Duranti A, Tontini A, Sanchini S, Sciolino NR, Spradley JM, Hohmann AG, Calignano A, Mor M, Tarzia G, Piomelli D. PMID: 20852626; PMCID: PMC3260554.
      View in: PubMed   Mentions: 113     Fields:    Translation:Animals
    221. Deficient liver biosynthesis of docosahexaenoic acid correlates with cognitive impairment in Alzheimer's disease. PLoS One. 2010 Sep 08; 5(9):e12538. Astarita G, Jung KM, Berchtold NC, Nguyen VQ, Gillen DL, Head E, Cotman CW, Piomelli D. PMID: 20838618; PMCID: PMC2935886.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    222. Synthesis and structure-activity relationships of N-(2-oxo-3-oxetanyl)amides as N-acylethanolamine-hydrolyzing acid amidase inhibitors. J Med Chem. 2010 Aug 12; 53(15):5770-81. Solorzano C, Antonietti F, Duranti A, Tontini A, Rivara S, Lodola A, Vacondio F, Tarzia G, Piomelli D, Mor M. PMID: 20604568; PMCID: PMC2932887.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    223. Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus. Neuropsychopharmacology. 2010 Sep; 35(10):2083-100. Bambico FR, Cassano T, Dominguez-Lopez S, Katz N, Walker CD, Piomelli D, Gobbi G. PMID: 20571484; PMCID: PMC3055302.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    224. The fat-induced satiety factor oleoylethanolamide suppresses feeding through central release of oxytocin. J Neurosci. 2010 Jun 16; 30(24):8096-101. Gaetani S, Fu J, Cassano T, Dipasquale P, Romano A, Righetti L, Cianci S, Laconca L, Giannini E, Scaccianoce S, Mairesse J, Cuomo V, Piomelli D. PMID: 20554860; PMCID: PMC2900249.
      View in: PubMed   Mentions: 45     Fields:    Translation:Animals
    225. Evidence for a role of endocannabinoids, astrocytes and p38 phosphorylation in the resolution of postoperative pain. PLoS One. 2010 May 28; 5(5):e10891. Alkaitis MS, Solorzano C, Landry RP, Piomelli D, DeLeo JA, Romero-Sandoval EA. PMID: 20531936; PMCID: PMC2878341.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    226. Pitfalls and solutions in assaying anandamide transport in cells. J Lipid Res. 2010 Aug; 51(8):2435-44. Oddi S, Fezza F, Catanzaro G, De Simone C, Pucci M, Piomelli D, Finazzi-Agrò A, Maccarrone M. PMID: 20447929; PMCID: PMC2903826.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    227. Social isolation and chronic handling alter endocannabinoid signaling and behavioral reactivity to context in adult rats. Neuroscience. 2010 Jun 30; 168(2):371-86. Sciolino NR, Bortolato M, Eisenstein SA, Fu J, Oveisi F, Hohmann AG, Piomelli D. PMID: 20394803; PMCID: PMC2882942.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    228. A role for 2-arachidonoylglycerol and endocannabinoid signaling in the locomotor response to novelty induced by olfactory bulbectomy. Pharmacol Res. 2010 May; 61(5):419-29. Eisenstein SA, Clapper JR, Holmes PV, Piomelli D, Hohmann AG. PMID: 20044005; PMCID: PMC2867105.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    229. Changes in cognition and amyloid-β processing with long term cholesterol reduction using atorvastatin in aged dogs. J Alzheimers Dis. 2010; 22(1):135-50. Murphy MP, Morales J, Beckett TL, Astarita G, Piomelli D, Weidner A, Studzinski CM, Dowling AL, Wang X, Levine H, Kryscio RJ, Lin Y, Barrett E, Head E. PMID: 20847439.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    230. FAAH deficiency promotes energy storage and enhances the motivation for food. Int J Obes (Lond). 2010 Mar; 34(3):557-68. Touriño C, Oveisi F, Lockney J, Piomelli D, Maldonado R. PMID: 20029375; PMCID: PMC3709605.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    231. Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation. Proc Natl Acad Sci U S A. 2009 Dec 08; 106(49):20966-71. Solorzano C, Zhu C, Battista N, Astarita G, Lodola A, Rivara S, Mor M, Russo R, Maccarrone M, Antonietti F, Duranti A, Tontini A, Cuzzocrea S, Tarzia G, Piomelli D. PMID: 19926854; PMCID: PMC2791595.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    232. A novel lipidomic strategy reveals plasma phospholipid signatures associated with respiratory disease severity in cystic fibrosis patients. PLoS One. 2009 Nov 06; 4(11):e7735. Guerrera IC, Astarita G, Jais JP, Sands D, Nowakowska A, Colas J, Sermet-Gaudelus I, Schuerenberg M, Piomelli D, Edelman A, Ollero M. PMID: 19893743; PMCID: PMC2768907.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    233. Discovery of potent and reversible monoacylglycerol lipase inhibitors. Chem Biol. 2009 Oct 30; 16(10):1045-52. King AR, Dotsey EY, Lodola A, Jung KM, Ghomian A, Qiu Y, Fu J, Mor M, Piomelli D. PMID: 19875078; PMCID: PMC3034734.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    234. CD36 gene deletion decreases oleoylethanolamide levels in small intestine of free-feeding mice. Pharmacol Res. 2010 Jan; 61(1):27-33. Guijarro A, Fu J, Astarita G, Piomelli D. PMID: 19778614; PMCID: PMC2846762.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    235. A second generation of carbamate-based fatty acid amide hydrolase inhibitors with improved activity in vivo. ChemMedChem. 2009 Sep; 4(9):1505-13. Clapper JR, Vacondio F, King AR, Duranti A, Tontini A, Silva C, Sanchini S, Tarzia G, Mor M, Piomelli D. PMID: 19637155; PMCID: PMC3016090.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    236. Structure-property relationships of a class of carbamate-based fatty acid amide hydrolase (FAAH) inhibitors: chemical and biological stability. ChemMedChem. 2009 Sep; 4(9):1495-504. Vacondio F, Silva C, Lodola A, Fioni A, Rivara S, Duranti A, Tontini A, Sanchini S, Clapper JR, Piomelli D, Mor M, Tarzia G. PMID: 19554599; PMCID: PMC3517974.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    237. A critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone-based enzyme inhibitors. Br J Pharmacol. 2009 Jul; 157(6):974-83. King AR, Lodola A, Carmi C, Fu J, Mor M, Piomelli D. PMID: 19486005; PMCID: PMC2737656.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    238. Fat-induced satiety factor oleoylethanolamide enhances memory consolidation. Proc Natl Acad Sci U S A. 2009 May 12; 106(19):8027-31. Campolongo P, Roozendaal B, Trezza V, Cuomo V, Astarita G, Fu J, McGaugh JL, Piomelli D. PMID: 19416833; PMCID: PMC2683095.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    239. Central administration of palmitoylethanolamide reduces hyperalgesia in mice via inhibition of NF-kappaB nuclear signalling in dorsal root ganglia. Eur J Pharmacol. 2009 Jun 24; 613(1-3):54-9. D'Agostino G, La Rana G, Russo R, Sasso O, Iacono A, Esposito E, Mattace Raso G, Cuzzocrea S, Loverme J, Piomelli D, Meli R, Calignano A. PMID: 19386271.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    240. An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. Psychopharmacology (Berl). 2009 Jul; 205(1):63-72. Mangieri RA, Hong KI, Piomelli D, Sinha R. PMID: 19343330; PMCID: PMC2715164.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    241. Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. Br J Psychiatry. 2009 Apr; 194(4):371-2. Koethe D, Giuffrida A, Schreiber D, Hellmich M, Schultze-Lutter F, Ruhrmann S, Klosterkötter J, Piomelli D, Leweke FM. PMID: 19336792.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    242. The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity. J Mass Spectrom. 2009 Apr; 44(4):561-5. Valitutti G, Duranti A, Mor M, Piersanti G, Piomelli D, Rivara S, Tontini A, Tarzia G, Traldi P. PMID: 19034887.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    243. The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew). Physiol Behav. 2009 Apr 20; 97(1):121-4. Parker LA, Limebeer CL, Rock EM, Litt DL, Kwiatkowska M, Piomelli D. PMID: 19239915; PMCID: PMC3781595.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    244. Responses to stress: from the periphery to the brain. Curr Opin Pharmacol. 2009 Feb; 9(1):1-2. Piomelli D. PMID: 19162545.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    245. Lipidomic analysis of endocannabinoid metabolism in biological samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Sep 15; 877(26):2755-67. Astarita G, Piomelli D. PMID: 19171504; PMCID: PMC2723187.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimals
    246. Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid. J Neural Transm (Vienna). 2009 Mar; 116(3):301-5. Koethe D, Schreiber D, Giuffrida A, Mauss C, Faulhaber J, Heydenreich B, Hellmich M, Graf R, Klosterkötter J, Piomelli D, Leweke FM. PMID: 19137236; PMCID: PMC2757605.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    247. The endocannabinoid system as a target for novel anxiolytic and antidepressant drugs. Int Rev Neurobiol. 2009; 85:57-72. Gaetani S, Dipasquale P, Romano A, Righetti L, Cassano T, Piomelli D, Cuomo V. PMID: 19607961.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimals
    248. Targeted lipidomics as a tool to investigate endocannabinoid function. Int Rev Neurobiol. 2009; 85:35-55. Astarita G, Geaga J, Ahmed F, Piomelli D. PMID: 19607960.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    249. Lipidomic analysis of biological samples by liquid chromatography coupled to mass spectrometry. Methods Mol Biol. 2009; 579:201-19. Astarita G, Ahmed F, Piomelli D. PMID: 19763477.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    250. The identification of peroxisome proliferator-activated receptor alpha-independent effects of oleoylethanolamide on intestinal transit in mice. Neurogastroenterol Motil. 2009 Apr; 21(4):420-9. Cluny NL, Keenan CM, Lutz B, Piomelli D, Sharkey KA. PMID: 19140957.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    251. Rapid pain modulation with nuclear receptor ligands. Brain Res Rev. 2009 Apr; 60(1):114-24. Fehrenbacher JC, Loverme J, Clarke W, Hargreaves KM, Piomelli D, Taylor BK. PMID: 19162071; PMCID: PMC3695814.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    252. Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice. Bioorg Med Chem Lett. 2009 Feb 01; 19(3):639-43. LoVerme J, Duranti A, Tontini A, Spadoni G, Mor M, Rivara S, Stella N, Xu C, Tarzia G, Piomelli D. PMID: 19128970; PMCID: PMC3690177.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimals
    253. Distribution and function of monoacylglycerol lipase in the gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol. 2008 Dec; 295(6):G1255-65. Duncan M, Thomas AD, Cluny NL, Patel A, Patel KD, Lutz B, Piomelli D, Alexander SP, Sharkey KA. PMID: 18948437.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    254. The lipid messenger OEA links dietary fat intake to satiety. Cell Metab. 2008 Oct; 8(4):281-288. Schwartz GJ, Fu J, Astarita G, Li X, Gaetani S, Campolongo P, Cuomo V, Piomelli D. PMID: 18840358; PMCID: PMC2572640.
      View in: PubMed   Mentions: 117     Fields:    Translation:AnimalsCells
    255. Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates. Biol Psychiatry. 2008 Dec 01; 64(11):930-7. Justinova Z, Mangieri RA, Bortolato M, Chefer SI, Mukhin AG, Clapper JR, King AR, Redhi GH, Yasar S, Piomelli D, Goldberg SR. PMID: 18814866; PMCID: PMC2701259.
      View in: PubMed   Mentions: 77     Fields:    Translation:Animals
    256. Role of endocannabinoids and their analogues in obesity and eating disorders. Eat Weight Disord. 2008 Sep; 13(3):e42-8. Gaetani S, Kaye WH, Cuomo V, Piomelli D. PMID: 19011363.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    257. Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in rats. J Pharmacol Exp Ther. 2008 Nov; 327(2):482-90. Scherma M, Panlilio LV, Fadda P, Fattore L, Gamaleddin I, Le Foll B, Justinová Z, Mikics E, Haller J, Medalie J, Stroik J, Barnes C, Yasar S, Tanda G, Piomelli D, Fratta W, Goldberg SR. PMID: 18725543; PMCID: PMC2663803.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    258. The endocannabinoid system as a target for the treatment of cannabis dependence. Neuropharmacology. 2009; 56 Suppl 1:235-43. Clapper JR, Mangieri RA, Piomelli D. PMID: 18691603; PMCID: PMC2647947.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    259. The element of surprise. Nat Med. 2008 Jul; 14(7):720-1. Piomelli D. PMID: 18607371.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    260. An endocannabinoid signaling system modulates anxiety-like behavior in male Syrian hamsters. Psychopharmacology (Berl). 2008 Oct; 200(3):333-46. Moise AM, Eisenstein SA, Astarita G, Piomelli D, Hohmann AG. PMID: 18545985; PMCID: PMC2694060.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    261. Synthesis and quantitative structure-activity relationship of fatty acid amide hydrolase inhibitors: modulation at the N-portion of biphenyl-3-yl alkylcarbamates. J Med Chem. 2008 Jun 26; 51(12):3487-98. Mor M, Lodola A, Rivara S, Vacondio F, Duranti A, Tontini A, Sanchini S, Piersanti G, Clapper JR, King AR, Tarzia G, Piomelli D. PMID: 18507372; PMCID: PMC3744893.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    262. Endogenous cannabinoids in patients with schizophrenia and substance use disorder during quetiapine therapy. J Psychopharmacol. 2008 May; 22(3):262-9. Potvin S, Kouassi E, Lipp O, Bouchard RH, Roy MA, Demers MF, Gendron A, Astarita G, Piomelli D, Stip E. PMID: 18308802.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    263. Improvement of general symptoms in a chronic psychotic patient treated with finasteride: case report. Pharmacopsychiatry. 2008 May; 41(3):115-6. Koethe D, Bortolato M, Piomelli D, Leweke FM. PMID: 18484553.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    264. Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat. Psychopharmacology (Berl). 2008 Jul; 198(4):449-60. Cippitelli A, Cannella N, Braconi S, Duranti A, Tontini A, Bilbao A, Defonseca FR, Piomelli D, Ciccocioppo R. PMID: 18446329.
      View in: PubMed   Mentions: 50     Fields:    Translation:Animals
    265. Targeted enhancement of oleoylethanolamide production in proximal small intestine induces across-meal satiety in rats. Am J Physiol Regul Integr Comp Physiol. 2008 Jul; 295(1):R45-50. Fu J, Kim J, Oveisi F, Astarita G, Piomelli D. PMID: 18434444; PMCID: PMC2494809.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    266. The endocannabinoid system in brain reward processes. Br J Pharmacol. 2008 May; 154(2):369-83. Solinas M, Goldberg SR, Piomelli D. PMID: 18414385; PMCID: PMC2442437.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansAnimalsCells
    267. Effects of palmitoylethanolamide on signaling pathways implicated in the development of spinal cord injury. J Pharmacol Exp Ther. 2008 Jul; 326(1):12-23. Genovese T, Esposito E, Mazzon E, Di Paola R, Meli R, Bramanti P, Piomelli D, Calignano A, Cuzzocrea S. PMID: 18367664.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    268. URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. Chem Biol. 2007 Dec; 14(12):1357-65. King AR, Duranti A, Tontini A, Rivara S, Rosengarth A, Clapper JR, Astarita G, Geaga JA, Luecke H, Mor M, Tarzia G, Piomelli D. PMID: 18096504; PMCID: PMC2225625.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    269. Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamate FAAH inhibitors. J Mass Spectrom. 2007 Dec; 42(12):1624-7. Valitutti G, Duranti A, Lodola A, Mor M, Piersanti G, Piomelli D, Rivara S, Tontini A, Tarzia G, Traldi P. PMID: 18085570.
      View in: PubMed   Mentions: 1     Fields:    
    270. The effect of cannabidiol and URB597 on conditioned gaping (a model of nausea) elicited by a lithium-paired context in the rat. Psychopharmacology (Berl). 2008 Feb; 196(3):389-95. Rock EM, Limebeer CL, Mechoulam R, Piomelli D, Parker LA. PMID: 17992520.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    271. AM404, an anandamide transport inhibitor, reduces plasma extravasation in a model of neuropathic pain in rat: role for cannabinoid receptors. Neuropharmacology. 2008 Mar; 54(3):521-9. La Rana G, Russo R, D'Agostino G, Sasso O, Raso GM, Iacono A, Meli R, Piomelli D, Calignano A. PMID: 18093621.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    272. Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain. J Lipid Res. 2008 Jan; 49(1):48-57. Astarita G, Ahmed F, Piomelli D. PMID: 17957091.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    273. Identification of productive inhibitor binding orientation in fatty acid amide hydrolase (FAAH) by QM/MM mechanistic modelling. Chem Commun (Camb). 2008 Jan 14; (2):214-6. Lodola A, Mor M, Rivara S, Christov C, Tarzia G, Piomelli D, Mulholland AJ. PMID: 18092091.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    274. A neuroscientist's guide to lipidomics. Nat Rev Neurosci. 2007 Oct; 8(10):743-54. Piomelli D, Astarita G, Rapaka R. PMID: 17882252.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansAnimalsCells
    275. Enhancement of endocannabinoid signaling and the pharmacotherapy of depression. Pharmacol Res. 2007 Nov; 56(5):360-6. Mangieri RA, Piomelli D. PMID: 17945507; PMCID: PMC2104793.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    276. Identification of a bioactive impurity in a commercial sample of 6-methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754). Ann Chim. 2007 Sep; 97(9):887-94. Tarzia G, Antonietti F, Duranti A, Tontini A, Mor M, Rivara S, Traldi P, Astarita G, King A, Clapper JR, Piomelli D. PMID: 17970304.
      View in: PubMed   Mentions: 9     Fields:    
    277. The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition. Neuropharmacology. 2008 Jan; 54(1):129-40. Scherma M, Medalie J, Fratta W, Vadivel SK, Makriyannis A, Piomelli D, Mikics E, Haller J, Yasar S, Tanda G, Goldberg SR. PMID: 17904589; PMCID: PMC2213536.
      View in: PubMed   Mentions: 62     Fields:    Translation:Animals
    278. Hydrolysis of prostaglandin glycerol esters by the endocannabinoid-hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase. Biochemistry. 2007 Aug 21; 46(33):9578-85. Vila A, Rosengarth A, Piomelli D, Cravatt B, Marnett LJ. PMID: 17649977.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    279. The anandamide transport inhibitor AM404 reduces ethanol self-administration. Eur J Neurosci. 2007 Jul; 26(2):476-86. Cippitelli A, Bilbao A, Gorriti MA, Navarro M, Massi M, Piomelli D, Ciccocioppo R, Rodríguez de Fonseca F. PMID: 17650118.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    280. A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization. Mol Pharmacol. 2007 Sep; 72(3):612-21. Jung KM, Astarita G, Zhu C, Wallace M, Mackie K, Piomelli D. PMID: 17584991.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    281. Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use. Schizophr Res. 2007 Aug; 94(1-3):29-36. Leweke FM, Giuffrida A, Koethe D, Schreiber D, Nolden BM, Kranaster L, Neatby MA, Schneider M, Gerth CW, Hellmich M, Klosterkötter J, Piomelli D. PMID: 17566707.
      View in: PubMed   Mentions: 66     Fields:    Translation:Humans
    282. Acute intracerebroventricular administration of palmitoylethanolamide, an endogenous peroxisome proliferator-activated receptor-alpha agonist, modulates carrageenan-induced paw edema in mice. J Pharmacol Exp Ther. 2007 Sep; 322(3):1137-43. D'Agostino G, La Rana G, Russo R, Sasso O, Iacono A, Esposito E, Raso GM, Cuzzocrea S, Lo Verme J, Piomelli D, Meli R, Calignano A. PMID: 17565008.
      View in: PubMed   Mentions: 57     Fields:    Translation:Animals
    283. The antinociceptive effects of local injections of propofol in rats are mediated in part by cannabinoid CB1 and CB2 receptors. Anesth Analg. 2007 Jun; 104(6):1563-9, table of contents. Guindon J, LoVerme J, Piomelli D, Beaulieu P. PMID: 17513659.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    284. Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress. Biol Psychiatry. 2007 Nov 15; 62(10):1103-10. Bortolato M, Mangieri RA, Fu J, Kim JH, Arguello O, Duranti A, Tontini A, Mor M, Tarzia G, Piomelli D. PMID: 17511970.
      View in: PubMed   Mentions: 126     Fields:    Translation:Animals
    285. Regulation of brain anandamide by acute administration of ethanol. Biochem J. 2007 May 15; 404(1):97-104. Ferrer B, Bermúdez-Silva FJ, Bilbao A, Alvarez-Jaimes L, Sanchez-Vera I, Giuffrida A, Serrano A, Baixeras E, Khaturia S, Navarro M, Parsons LH, Piomelli D, Rodríguez de Fonseca F. PMID: 17302558; PMCID: PMC1868843.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    286. The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice. J Pharmacol Exp Ther. 2007 Jul; 322(1):236-42. Russo R, Loverme J, La Rana G, Compton TR, Parrott J, Duranti A, Tontini A, Mor M, Tarzia G, Calignano A, Piomelli D. PMID: 17412883.
      View in: PubMed   Mentions: 84     Fields:    Translation:Animals
    287. Synergistic antinociception by the cannabinoid receptor agonist anandamide and the PPAR-alpha receptor agonist GW7647. Eur J Pharmacol. 2007 Jul 02; 566(1-3):117-9. Russo R, LoVerme J, La Rana G, D'Agostino G, Sasso O, Calignano A, Piomelli D. PMID: 17434479; PMCID: PMC1997313.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    288. The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport. J Pharmacol Exp Ther. 2007 Apr; 321(1):370-80. Solinas M, Tanda G, Justinova Z, Wertheim CE, Yasar S, Piomelli D, Vadivel SK, Makriyannis A, Goldberg SR. PMID: 17210800.
      View in: PubMed   Mentions: 60     Fields:    Translation:Animals
    289. Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry. Anal Biochem. 2007 Feb 15; 361(2):162-8. Schreiber D, Harlfinger S, Nolden BM, Gerth CW, Jaehde U, Schömig E, Klosterkötter J, Giuffrida A, Astarita G, Piomelli D, Markus Leweke F. PMID: 17196922.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    290. Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine. J Biol Chem. 2007 Jan 12; 282(2):1518-28. Fu J, Astarita G, Gaetani S, Kim J, Cravatt BF, Mackie K, Piomelli D. PMID: 17121838; PMCID: PMC1764767.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    291. Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. Psychopharmacology (Berl). 2007 Feb; 190(2):135-43. Cross-Mellor SK, Ossenkopp KP, Piomelli D, Parker LA. PMID: 17111174.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    292. Conformational effects in enzyme catalysis: reaction via a high energy conformation in fatty acid amide hydrolase. Biophys J. 2007 Jan 15; 92(2):L20-2. Lodola A, Mor M, Zurek J, Tarzia G, Piomelli D, Harvey JN, Mulholland AJ. PMID: 17098788; PMCID: PMC1751413.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    293. Rapid broad-spectrum analgesia through activation of peroxisome proliferator-activated receptor-alpha. J Pharmacol Exp Ther. 2006 Dec; 319(3):1051-61. LoVerme J, Russo R, La Rana G, Fu J, Farthing J, Mattace-Raso G, Meli R, Hohmann A, Calignano A, Piomelli D. PMID: 16997973.
      View in: PubMed   Mentions: 139     Fields:    Translation:AnimalsCells
    294. Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides? Eur J Pharmacol. 2006 Nov 21; 550(1-3):68-77. Guindon J, LoVerme J, De Léan A, Piomelli D, Beaulieu P. PMID: 17027744.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    295. Presence of depolarization-induced suppression of inhibition in a fraction of GABAergic synaptic connections in rat neocortical cultures. Neurosci Behav Physiol. 2006 Sep; 36(7):709-13. Storozhuk MV, Ivanova SY, Piomelli D. PMID: 16841150.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    296. The cannabinoid receptor agonist WIN 55,212-2 attenuates the effects induced by quinolinic acid in the rat striatum. Neuropharmacology. 2006 Oct; 51(5):1004-12. Pintor A, Tebano MT, Martire A, Grieco R, Galluzzo M, Scattoni ML, Pèzzola A, Coccurello R, Felici F, Cuomo V, Piomelli D, Calamandrei G, Popoli P. PMID: 16895732.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    297. The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues. Pharmacol Res. 2006 Nov; 54(5):341-4. Clapper JR, Duranti A, Tontini A, Mor M, Tarzia G, Piomelli D. PMID: 16935521.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    298. Cold exposure stimulates synthesis of the bioactive lipid oleoylethanolamide in rat adipose tissue. J Biol Chem. 2006 Aug 11; 281(32):22815-8. LoVerme J, Guzmán M, Gaetani S, Piomelli D. PMID: 16785227.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    299. Molecular composition of the endocannabinoid system at glutamatergic synapses. J Neurosci. 2006 May 24; 26(21):5628-37. Katona I, Urbán GM, Wallace M, Ledent C, Jung KM, Piomelli D, Mackie K, Freund TF. PMID: 16723519; PMCID: PMC1698282.
      View in: PubMed   Mentions: 215     Fields:    Translation:AnimalsCells
    300. Pharmacological characterization of hydrolysis-resistant analogs of oleoylethanolamide with potent anorexiant properties. J Pharmacol Exp Ther. 2006 Aug; 318(2):563-70. Astarita G, Di Giacomo B, Gaetani S, Oveisi F, Compton TR, Rivara S, Tarzia G, Mor M, Piomelli D. PMID: 16702440.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    301. Anxiolytic-like properties of the anandamide transport inhibitor AM404. Neuropsychopharmacology. 2006 Dec; 31(12):2652-9. Bortolato M, Campolongo P, Mangieri RA, Scattoni ML, Frau R, Trezza V, La Rana G, Russo R, Calignano A, Gessa GL, Cuomo V, Piomelli D. PMID: 16541083.
      View in: PubMed   Mentions: 76     Fields:    Translation:Animals
    302. Modulation of neuropathic and inflammatory pain by the endocannabinoid transport inhibitor AM404 [N-(4-hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide]. J Pharmacol Exp Ther. 2006 Jun; 317(3):1365-71. La Rana G, Russo R, Campolongo P, Bortolato M, Mangieri RA, Cuomo V, Iacono A, Raso GM, Meli R, Piomelli D, Calignano A. PMID: 16510698.
      View in: PubMed   Mentions: 41     Fields:    Translation:Animals
    303. Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models. Br J Pharmacol. 2006 Feb; 147(3):281-8. Jayamanne A, Greenwood R, Mitchell VA, Aslan S, Piomelli D, Vaughan CW. PMID: 16331291; PMCID: PMC1751298.
      View in: PubMed   Mentions: 105     Fields:    Translation:Animals
    304. Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597). CNS Drug Rev. 2006; 12(1):21-38. Piomelli D, Tarzia G, Duranti A, Tontini A, Mor M, Compton TR, Dasse O, Monaghan EP, Parrott JA, Putman D. PMID: 16834756; PMCID: PMC6741741.
      View in: PubMed   Mentions: 135     Fields:    Translation:HumansAnimalsCells
    305. Synthesis and structure-activity relationships of FAAH inhibitors: cyclohexylcarbamic acid biphenyl esters with chemical modulation at the proximal phenyl ring. ChemMedChem. 2006 Jan; 1(1):130-9. Tarzia G, Duranti A, Gatti G, Piersanti G, Tontini A, Rivara S, Lodola A, Plazzi PV, Mor M, Kathuria S, Piomelli D. PMID: 16892344.
      View in: PubMed   Mentions: 21     Fields:    
    306. Role of the basolateral nucleus of the amygdala in endocannabinoid-mediated stress-induced analgesia. Neurosci Lett. 2006 Apr 24; 397(3):180-4. Connell K, Bolton N, Olsen D, Piomelli D, Hohmann AG. PMID: 16378681.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    307. Postprandial increase of oleoylethanolamide mobilization in small intestine of the Burmese python (Python molurus). Am J Physiol Regul Integr Comp Physiol. 2006 May; 290(5):R1407-12. Astarita G, Rourke BC, Andersen JB, Fu J, Kim JH, Bennett AF, Hicks JW, Piomelli D. PMID: 16373434.
      View in: PubMed   Mentions: 24  Translation:Animals
    308. Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18620-5. Gobbi G, Bambico FR, Mangieri R, Bortolato M, Campolongo P, Solinas M, Cassano T, Morgese MG, Debonnel G, Duranti A, Tontini A, Tarzia G, Mor M, Trezza V, Goldberg SR, Cuomo V, Piomelli D. PMID: 16352709; PMCID: PMC1317988.
      View in: PubMed   Mentions: 228     Fields:    Translation:AnimalsCells
    309. Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia. Neuropharmacology. 2006 Mar; 50(3):372-9. Suplita RL, Gutierrez T, Fegley D, Piomelli D, Hohmann AG. PMID: 16316669.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    310. Oleylethanolamide activates Ras-Erk pathway and improves myocardial function in doxorubicin-induced heart failure. Endocrinology. 2006 Feb; 147(2):827-34. Su HF, Samsamshariat A, Fu J, Shan YX, Chen YH, Piomelli D, Wang PH. PMID: 16269455.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    311. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science. 2005 Oct 14; 310(5746):329-32. Van Sickle MD, Duncan M, Kingsley PJ, Mouihate A, Urbani P, Mackie K, Stella N, Makriyannis A, Piomelli D, Davison JS, Marnett LJ, Di Marzo V, Pittman QJ, Patel KD, Sharkey KA. PMID: 16224028.
      View in: PubMed   Mentions: 489     Fields:    Translation:Animals
    312. The challenge of brain lipidomics. Prostaglandins Other Lipid Mediat. 2005 Sep; 77(1-4):23-34. Piomelli D. PMID: 16099388.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    313. Presence of depolarization-induced suppression of inhibition in a fraction of gabaergic synaptic connections in rat neocortical cultures. Zh Vyssh Nerv Deiat Im I P Pavlova. 2005 Sep-Oct; 55(5):581-5. Storozhuk MV, Ivanova SY, Piomelli D. PMID: 16316018.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    314. Targeted lipidomics: signaling lipids and drugs of abuse. Prostaglandins Other Lipid Mediat. 2005 Sep; 77(1-4):223-34. Rapaka RS, Piomelli D, Spiegel S, Bazan N, Dennis EA. PMID: 16099407.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    315. The search for the palmitoylethanolamide receptor. Life Sci. 2005 Aug 19; 77(14):1685-98. LoVerme J, La Rana G, Russo R, Calignano A, Piomelli D. PMID: 15963531.
      View in: PubMed   Mentions: 92     Fields:    
    316. Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus. Nat Neurosci. 2005 Sep; 8(9):1139-41. Makara JK, Mor M, Fegley D, Szabó SI, Kathuria S, Astarita G, Duranti A, Tontini A, Tarzia G, Rivara S, Freund TF, Piomelli D. PMID: 16116451.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    317. A role for endocannabinoids in viral-induced dyskinetic and convulsive phenomena. Exp Neurol. 2005 Aug; 194(2):355-62. Solbrig MV, Adrian R, Baratta J, Piomelli D, Giuffrida A. PMID: 16022863.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    318. Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors. Mol Pharmacol. 2005 Nov; 68(5):1196-202. Jung KM, Mangieri R, Stapleton C, Kim J, Fegley D, Wallace M, Mackie K, Piomelli D. PMID: 16051747.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    319. QM/MM modelling of oleamide hydrolysis in fatty acid amide hydrolase (FAAH) reveals a new mechanism of nucleophile activation. Chem Commun (Camb). 2005 Sep 21; (35):4399-401. Lodola A, Mor M, Hermann JC, Tarzia G, Piomelli D, Mulholland AJ. PMID: 16136230.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    320. The endocannabinoid system: a drug discovery perspective. Curr Opin Investig Drugs. 2005 Jul; 6(7):672-9. Piomelli D. PMID: 16044662.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    321. An endocannabinoid mechanism for stress-induced analgesia. Nature. 2005 Jun 23; 435(7045):1108-12. Hohmann AG, Suplita RL, Bolton NM, Neely MH, Fegley D, Mangieri R, Krey JF, Walker JM, Holmes PV, Crystal JD, Duranti A, Tontini A, Mor M, Tarzia G, Piomelli D. PMID: 15973410.
      View in: PubMed   Mentions: 246     Fields:    Translation:AnimalsCells
    322. Therapeutic opportunities through modulation of the endocannabinoid system. Neuropharmacology. 2005 Jun; 48(8):1068-71. Makriyannis A, Mechoulam R, Piomelli D. PMID: 15885714.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    323. Oleoylethanolamide, an endogenous PPAR-alpha agonist, lowers body weight and hyperlipidemia in obese rats. Neuropharmacology. 2005 Jun; 48(8):1147-53. Fu J, Oveisi F, Gaetani S, Lin E, Piomelli D. PMID: 15910890.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    324. Regulation of food intake by oleoylethanolamide. Cell Mol Life Sci. 2005 Mar; 62(6):708-16. Lo Verme J, Gaetani S, Fu J, Oveisi F, Burton K, Piomelli D. PMID: 15770421.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    325. Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation. J Pharmacol Exp Ther. 2005 Apr; 313(1):352-8. Fegley D, Gaetani S, Duranti A, Tontini A, Mor M, Tarzia G, Piomelli D. PMID: 15579492.
      View in: PubMed   Mentions: 183     Fields:    Translation:Animals
    326. Tandem mass spectrometric data-FAAH inhibitory activity relationships of some carbamic acid O-aryl esters. J Mass Spectrom. 2004 Dec; 39(12):1450-5. Basso E, Duranti A, Mor M, Piomelli D, Tontini A, Tarzia G, Traldi P. PMID: 15578755.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    327. Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms. Neuropsychopharmacology. 2004 Nov; 29(11):2108-14. Giuffrida A, Leweke FM, Gerth CW, Schreiber D, Koethe D, Faulhaber J, Klosterkötter J, Piomelli D. PMID: 15354183.
      View in: PubMed   Mentions: 123     Fields:    Translation:Humans
    328. Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies. J Med Chem. 2004 Oct 07; 47(21):4998-5008. Mor M, Rivara S, Lodola A, Plazzi PV, Tarzia G, Duranti A, Tontini A, Piersanti G, Kathuria S, Piomelli D. PMID: 15456244.
      View in: PubMed   Mentions: 89     Fields:    Translation:Animals
    329. The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide. Mol Pharmacol. 2005 Jan; 67(1):15-9. Lo Verme J, Fu J, Astarita G, La Rana G, Russo R, Calignano A, Piomelli D. PMID: 15465922.
      View in: PubMed   Mentions: 297     Fields:    Translation:HumansAnimalsCells
    330. RNA interference suggests a primary role for monoacylglycerol lipase in the degradation of the endocannabinoid 2-arachidonoylglycerol. Mol Pharmacol. 2004 Nov; 66(5):1260-4. Dinh TP, Kathuria S, Piomelli D. PMID: 15272052.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    331. Segregation of two endocannabinoid-hydrolyzing enzymes into pre- and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala. Eur J Neurosci. 2004 Jul; 20(2):441-58. Gulyas AI, Cravatt BF, Bracey MH, Dinh TP, Piomelli D, Boscia F, Freund TF. PMID: 15233753.
      View in: PubMed   Mentions: 157     Fields:    Translation:AnimalsCells
    332. Endocannabinoid transport tightly controls 2-arachidonoyl glycerol actions in the hippocampus: effects of low temperature and the transport inhibitor AM404. Eur J Neurosci. 2004 Jun; 19(11):2991-6. Hájos N, Kathuria S, Dinh T, Piomelli D, Freund TF. PMID: 15182306.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    333. Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. Proc Natl Acad Sci U S A. 2004 Jun 08; 101(23):8756-61. Fegley D, Kathuria S, Mercier R, Li C, Goutopoulos A, Makriyannis A, Piomelli D. PMID: 15138300; PMCID: PMC423268.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    334. Oleoylethanolamide inhibits food intake in free-feeding rats after oral administration. Pharmacol Res. 2004 May; 49(5):461-6. Oveisi F, Gaetani S, Eng KT, Piomelli D. PMID: 14998556.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    335. Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha). J Biol Chem. 2004 Jul 02; 279(27):27849-54. Guzmán M, Lo Verme J, Fu J, Oveisi F, Blázquez C, Piomelli D. PMID: 15123613.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    336. THC: moderation during implantation. Nat Med. 2004 Jan; 10(1):19-20. Piomelli D. PMID: 14702623.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    337. The endogenous cannabinoid system and the treatment of marijuana dependence. Neuropharmacology. 2004; 47 Suppl 1:359-67. Piomelli D. PMID: 15464150.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    338. Anandamide enhances extracellular levels of adenosine and induces sleep: an in vivo microdialysis study. Sleep. 2003 Dec 15; 26(8):943-7. Murillo-Rodriguez E, Blanco-Centurion C, Sanchez C, Piomelli D, Shiromani PJ. PMID: 14746372.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    339. Exercise activates the endocannabinoid system. Neuroreport. 2003 Dec 02; 14(17):2209-11. Sparling PB, Giuffrida A, Piomelli D, Rosskopf L, Dietrich A. PMID: 14625449.
      View in: PubMed   Mentions: 66     Fields:    Translation:Humans
    340. The molecular logic of endocannabinoid signalling. Nat Rev Neurosci. 2003 Nov; 4(11):873-84. Piomelli D. PMID: 14595399.
      View in: PubMed   Mentions: 624     Fields:    Translation:HumansAnimalsCells
    341. Anandamide hydrolysis: a new target for anti-anxiety drugs? Trends Mol Med. 2003 Nov; 9(11):474-8. Gaetani S, Cuomo V, Piomelli D. PMID: 14604824.
      View in: PubMed   Mentions: 27     Fields:    
    342. Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha. Nature. 2003 Sep 04; 425(6953):90-3. Fu J, Gaetani S, Oveisi F, Lo Verme J, Serrano A, Rodríguez De Fonseca F, Rosengarth A, Luecke H, Di Giacomo B, Tarzia G, Piomelli D. PMID: 12955147.
      View in: PubMed   Mentions: 338     Fields:    Translation:HumansAnimalsCells
    343. Synthesis and structure-activity relationships of a series of pyrrole cannabinoid receptor agonists. Bioorg Med Chem. 2003 Sep 01; 11(18):3965-73. Tarzia G, Duranti A, Tontini A, Spadoni G, Mor M, Rivara S, Vincenzo Plazzi P, Kathuria S, Piomelli D. PMID: 12927857.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    344. Effects of levodopa on endocannabinoid levels in rat basal ganglia: implications for the treatment of levodopa-induced dyskinesias. Eur J Neurosci. 2003 Sep; 18(6):1607-14. Ferrer B, Asbrock N, Kathuria S, Piomelli D, Giuffrida A. PMID: 14511339.
      View in: PubMed   Mentions: 46     Fields:    Translation:Animals
    345. Long-term plasticity of endocannabinoid signaling induced by developmental febrile seizures. Neuron. 2003 Aug 14; 39(4):599-611. Chen K, Ratzliff A, Hilgenberg L, Gulyás A, Freund TF, Smith M, Dinh TP, Piomelli D, Mackie K, Soltesz I. PMID: 12925275.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    346. Role of endogenous cannabinoids in synaptic signaling. Physiol Rev. 2003 Jul; 83(3):1017-66. Freund TF, Katona I, Piomelli D. PMID: 12843414.
      View in: PubMed   Mentions: 496     Fields:    Translation:HumansAnimalsCells
    347. Design, synthesis, and structure-activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors. J Med Chem. 2003 Jun 05; 46(12):2352-60. Tarzia G, Duranti A, Tontini A, Piersanti G, Mor M, Rivara S, Plazzi PV, Park C, Kathuria S, Piomelli D. PMID: 12773040.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    348. Modulation of meal pattern in the rat by the anorexic lipid mediator oleoylethanolamide. Neuropsychopharmacology. 2003 Jul; 28(7):1311-6. Gaetani S, Oveisi F, Piomelli D. PMID: 12700681.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    349. N-Acylethanolamines in human reproductive fluids. Chem Phys Lipids. 2002 Dec 31; 121(1-2):211-27. Schuel H, Burkman LJ, Lippes J, Crickard K, Forester E, Piomelli D, Giuffrida A. PMID: 12505702.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimals
    350. A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation. Chem Phys Lipids. 2002 Dec 31; 121(1-2):149-58. Dinh TP, Freund TF, Piomelli D. PMID: 12505697.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    351. Modulation of anxiety through blockade of anandamide hydrolysis. Nat Med. 2003 Jan; 9(1):76-81. Kathuria S, Gaetani S, Fegley D, Valiño F, Duranti A, Tontini A, Mor M, Tarzia G, La Rana G, Calignano A, Giustino A, Tattoli M, Palmery M, Cuomo V, Piomelli D. PMID: 12461523.
      View in: PubMed   Mentions: 503     Fields:    Translation:HumansAnimalsCells
    352. Attenuation of spontaneous opiate withdrawal in mice by the anandamide transport inhibitor AM404. Eur J Pharmacol. 2002 Nov 01; 454(1):103-4. Del Arco I, Navarro M, Bilbao A, Ferrer B, Piomelli D, Rodríguez De Fonseca F. PMID: 12409011.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    353. A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding. J Neurosci. 2002 Nov 01; 22(21):9612-7. Gómez R, Navarro M, Ferrer B, Trigo JM, Bilbao A, Del Arco I, Cippitelli A, Nava F, Piomelli D, Rodríguez de Fonseca F. PMID: 12417686; PMCID: PMC6758016.
      View in: PubMed   Mentions: 133     Fields:    Translation:Animals
    354. Release of fatty acid amides in a patient with hemispheric stroke: a microdialysis study. Stroke. 2002 Aug; 33(8):2112-4. Schäbitz WR, Giuffrida A, Berger C, Aschoff A, Schwaninger M, Schwab S, Piomelli D. PMID: 12154273.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    355. Brain monoglyceride lipase participating in endocannabinoid inactivation. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10819-24. Dinh TP, Carpenter D, Leslie FM, Freund TF, Katona I, Sensi SL, Kathuria S, Piomelli D. PMID: 12136125; PMCID: PMC125056.
      View in: PubMed   Mentions: 432     Fields:    Translation:HumansAnimalsCells
    356. An anorexic lipid mediator regulated by feeding. Nature. 2001 Nov 08; 414(6860):209-12. Rodríguez de Fonseca F, Navarro M, Gómez R, Escuredo L, Nava F, Fu J, Murillo-Rodríguez E, Giuffrida A, LoVerme J, Gaetani S, Kathuria S, Gall C, Piomelli D. PMID: 11700558.
      View in: PubMed   Mentions: 186     Fields:    Translation:Animals
    357. Cannabinoid activity curtails cocaine craving. Nat Med. 2001 Oct; 7(10):1099-100. Piomelli D. PMID: 11590424.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    358. Receptor-dependent formation of endogenous cannabinoids in cortical neurons. Eur J Pharmacol. 2001 Aug 17; 425(3):189-96. Stella N, Piomelli D. PMID: 11513837.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    359. Mechanisms of endocannabinoid inactivation: biochemistry and pharmacology. J Pharmacol Exp Ther. 2001 Jul; 298(1):7-14. Giuffrida A, Beltramo M, Piomelli D. PMID: 11408519.
      View in: PubMed   Mentions: 51     Fields:    
    360. Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide. Eur J Pharmacol. 2001 May 11; 419(2-3):191-8. Calignano A, La Rana G, Piomelli D. PMID: 11426841.
      View in: PubMed   Mentions: 63     Fields:    Translation:Animals
    361. Role of the endogenous cannabinoid system as a modulator of dopamine transmission: implications for Parkinson's disease and schizophrenia. Neurotox Res. 2001 Jan; 3(1):23-35. Rodríguez De Fonseca F, Gorriti MA, Bilbao A, Escuredo L, García-Segura LM, Piomelli D, Navarro M. PMID: 15111259.
      View in: PubMed   Mentions: 18     Fields:    
    362. The ligand that came from within. Trends Pharmacol Sci. 2001 Jan; 22(1):17-9. Piomelli D. PMID: 11165666.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    363. Elevated circulating levels of anandamide after administration of the transport inhibitor, AM404. Eur J Pharmacol. 2000 Nov 17; 408(2):161-8. Giuffrida A, Rodriguez de Fonseca F, Nava F, Loubet-Lescoulié P, Piomelli D. PMID: 11080522.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    364. Bidirectional control of airway responsiveness by endogenous cannabinoids. Nature. 2000 Nov 02; 408(6808):96-101. Calignano A, Kátona I, Désarnaud F, Giuffrida A, La Rana G, Mackie K, Freund TF, Piomelli D. PMID: 11081515.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    365. The endocannabinoid system: a physiological perspective on its role in psychomotor control. Chem Phys Lipids. 2000 Nov; 108(1-2):151-8. Giuffrida A, Piomelli D. PMID: 11106788.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    366. The endocannabinoid system as a target for therapeutic drugs. Trends Pharmacol Sci. 2000 Jun; 21(6):218-24. Piomelli D, Giuffrida A, Calignano A, Rodríguez de Fonseca F. PMID: 10838609.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimals
    367. Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitor. J Neurosci. 2000 May 01; 20(9):3401-7. Beltramo M, de Fonseca FR, Navarro M, Calignano A, Gorriti MA, Grammatikopoulos G, Sadile AG, Giuffrida A, Piomelli D. PMID: 10777802; PMCID: PMC6773117.
      View in: PubMed   Mentions: 51     Fields:    Translation:Animals
    368. Carrier-mediated transport and enzymatic hydrolysis of the endogenous cannabinoid 2-arachidonylglycerol. Neuroreport. 2000 Apr 27; 11(6):1231-5. Beltramo M, Piomelli D. PMID: 10817598.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    369. Quantification of bioactive acylethanolamides in rat plasma by electrospray mass spectrometry. Anal Biochem. 2000 Apr 10; 280(1):87-93. Giuffrida A, Rodríguez de Fonseca F, Piomelli D. PMID: 10805525.
      View in: PubMed   Mentions: 50     Fields:    Translation:Animals
    370. Endogenous cannabinoid signaling and psychomotor disorders. Prostaglandins Other Lipid Mediat. 2000 Apr; 61(1-2):63-70. Giuffrida A, Désarnaud F, Piomelli D. PMID: 10785542.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    371. Pot of gold for glioma therapy. Nat Med. 2000 Mar; 6(3):255-6. Piomelli D. PMID: 10700220.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    372. A role for the endogenous cannabinoid system in the peripheral control of pain initiation. Prog Brain Res. 2000; 129:471-82. Calignano A, La Rana G, Loubet-Lescoulié P, Piomelli D. PMID: 11098711.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    373. Cannabinoid CB1 receptors and ligands in vertebrate retina: localization and function of an endogenous signaling system. Proc Natl Acad Sci U S A. 1999 Dec 07; 96(25):14565-70. Straiker A, Stella N, Piomelli D, Mackie K, Karten HJ, Maguire G. PMID: 10588745; PMCID: PMC24476.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    374. Elevated endogenous cannabinoids in schizophrenia. Neuroreport. 1999 Jun 03; 10(8):1665-9. Leweke FM, Giuffrida A, Wurster U, Emrich HM, Piomelli D. PMID: 10501554.
      View in: PubMed   Mentions: 102     Fields:    Translation:Humans
    375. Structural determinants for recognition and translocation by the anandamide transporter. Proc Natl Acad Sci U S A. 1999 May 11; 96(10):5802-7. Piomelli D, Beltramo M, Glasnapp S, Lin SY, Goutopoulos A, Xie XQ, Makriyannis A. PMID: 10318965; PMCID: PMC21941.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    376. Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. Nat Neurosci. 1999 Apr; 2(4):358-63. Giuffrida A, Parsons LH, Kerr TM, Rodríguez de Fonseca F, Navarro M, Piomelli D. PMID: 10204543.
      View in: PubMed   Mentions: 212     Fields:    Translation:AnimalsCells
    377. Anandamide transport inhibition by the vanilloid agonist olvanil. Eur J Pharmacol. 1999 Jan 01; 364(1):75-8. Beltramo M, Piomelli D. PMID: 9920187.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    378. Endogenous cannabinoid signaling. Neurobiol Dis. 1998 Dec; 5(6 Pt B):462-73. Piomelli D, Beltramo M, Giuffrida A, Stella N. PMID: 9974178.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    379. Control of pain initiation by endogenous cannabinoids. Nature. 1998 Jul 16; 394(6690):277-81. Calignano A, La Rana G, Giuffrida A, Piomelli D. PMID: 9685157.
      View in: PubMed   Mentions: 273     Fields:    Translation:Animals
    380. Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma. FEBS Lett. 1998 Feb 06; 422(3):373-6. Giuffrida A, Piomelli D. PMID: 9498819.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    381. Inhibition of intestinal motility by anandamide, an endogenous cannabinoid. Eur J Pharmacol. 1997 Dec 11; 340(2-3):R7-8. Calignano A, La Rana G, Makriyannis A, Lin SY, Beltramo M, Piomelli D. PMID: 9537804.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    382. Potentiation of anandamide hypotension by the transport inhibitor, AM404. Eur J Pharmacol. 1997 Oct 15; 337(1):R1-2. Calignano A, La Rana G, Beltramo M, Makriyannis A, Piomelli D. PMID: 9389389.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    383. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. Science. 1997 Aug 22; 277(5329):1094-7. Beltramo M, Stella N, Calignano A, Lin SY, Makriyannis A, Piomelli D. PMID: 9262477.
      View in: PubMed   Mentions: 192     Fields:    Translation:AnimalsCells
    384. A second endogenous cannabinoid that modulates long-term potentiation. Nature. 1997 Aug 21; 388(6644):773-8. Stella N, Schweitzer P, Piomelli D. PMID: 9285589.
      View in: PubMed   Mentions: 396     Fields:    Translation:AnimalsCells
    385. Interleukin-1 enhances the ATP-evoked release of arachidonic acid from mouse astrocytes. J Neurosci. 1997 May 01; 17(9):2939-46. Stella N, Estellés A, Siciliano J, Tencé M, Desagher S, Piomelli D, Glowinski J, Prémont J. PMID: 9096130; PMCID: PMC6573655.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    386. Inhibition of anandamide hydrolysis in rat brain tissue by (E)-6-(bromomethylene) tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one. FEBS Lett. 1997 Feb 24; 403(3):263-7. Beltramo M, di Tomaso E, Piomelli D. PMID: 9091314.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    387. Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain. J Neurosci. 1997 Feb 15; 17(4):1226-42. Cadas H, di Tomaso E, Piomelli D. PMID: 9006968; PMCID: PMC6793739.
      View in: PubMed   Mentions: 93     Fields:    Translation:Animals
    388. Endogenous lipids that activate cannabinoid receptors. Formation and inactivation. Adv Exp Med Biol. 1997; 407:335-40. Di Tomaso E, Cadas H, Gaillet S, Beltramo M, Desarnaud F, Venance L, Piomelli D. PMID: 9321973.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    389. Medicinal plants for the treatment of urogenital tract pathologies according to Dioscorides' De Materia Medica. Am J Nephrol. 1997; 17(3-4):241-7. Touwaide A, Pollio A, Aliotta G, Piomelli D, De Santo NG. PMID: 9189241.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    390. Membrane localization of N-acylphosphatidylethanolamine in central neurons: studies with exogenous phospholipases. J Lipid Mediat Cell Signal. 1996 Sep; 14(1-3):63-70. Cadas H, Schinelli S, Piomelli D. PMID: 8906547.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    391. Brain cannabinoids in chocolate. Nature. 1996 Aug 22; 382(6593):677-8. di Tomaso E, Beltramo M, Piomelli D. PMID: 8751435.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    392. Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP. J Neurosci. 1996 Jun 15; 16(12):3934-42. Cadas H, Gaillet S, Beltramo M, Venance L, Piomelli D. PMID: 8656287; PMCID: PMC6578613.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    393. Arachidonate 5-lipoxygenase and its activating protein: prominent hippocampal expression and role in somatostatin signaling. J Neurochem. 1996 Jan; 66(1):147-52. Lammers CH, Schweitzer P, Facchinetti P, Arrang JM, Madamba SG, Siggins GR, Piomelli D. PMID: 8522947.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    394. Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines. Prostaglandins Leukot Essent Fatty Acids. 1995 Oct; 53(4):301-8. Fontana A, Di Marzo V, Cadas H, Piomelli D. PMID: 8577784.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    395. Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes. Nature. 1995 Aug 17; 376(6541):590-4. Venance L, Piomelli D, Glowinski J, Giaume C. PMID: 7637807.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    396. Dopamine D2 receptors potentiate arachidonate release via activation of cytosolic, arachidonate-specific phospholipase A2. J Neurochem. 1995 Jun; 64(6):2765-72. Vial D, Piomelli D. PMID: 7760057.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    397. Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization. J Biol Chem. 1995 Mar 17; 270(11):6030-5. Desarnaud F, Cadas H, Piomelli D. PMID: 7890734.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    398. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. Nature. 1994 Dec 15; 372(6507):686-91. Di Marzo V, Fontana A, Cadas H, Schinelli S, Cimino G, Schwartz JC, Piomelli D. PMID: 7990962.
      View in: PubMed   Mentions: 386     Fields:    Translation:AnimalsCells
    399. A study in Renaissance psychotropic plant ointments. Hist Philos Life Sci. 1994; 16(2):241-73. Piomelli D, Pollio A. PMID: 7724723.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    400. Eicosanoids in synaptic transmission. Crit Rev Neurobiol. 1994; 8(1-2):65-83. Piomelli D. PMID: 8124731.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    401. Selection of alternative G-mediated signaling pathways at the dopamine D2 receptor by protein kinase C. J Neurosci. 1993 Nov; 13(11):4846-53. Di Marzo V, Vial D, Sokoloff P, Schwartz JC, Piomelli D. PMID: 7693893; PMCID: PMC6576345.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    402. Barium evokes glutamate release from rat brain synaptosomes by membrane depolarization: involvement of K+, Na+, and Ca2+ channels. J Neurochem. 1993 Oct; 61(4):1220-30. Sihra TS, Piomelli D, Nichols RA. PMID: 7690845.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    403. Arachidonic acid in cell signaling. Curr Opin Cell Biol. 1993 Apr; 5(2):274-80. Piomelli D. PMID: 7685181.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    404. Dopamine D2 receptor signaling via the arachidonic acid cascade: modulation by cAMP-dependent protein kinase A and prostaglandin E2. J Lipid Mediat. 1993 Mar-Apr; 6(1-3):433-43. Piomelli D, Di Marzo V. PMID: 8395253.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    405. Participation of prostaglandin E2 in dopamine D2 receptor-dependent potentiation of arachidonic acid release. J Neurochem. 1992 Jul; 59(1):379-82. Di Marzo V, Piomelli D. PMID: 1351931.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    406. Expression of a cloned rat histamine H2 receptor mediating inhibition of arachidonate release and activation of cAMP accumulation. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):2649-53. Traiffort E, Ruat M, Arrang JM, Leurs R, Piomelli D, Schwartz JC. PMID: 1313563; PMCID: PMC48719.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    407. Molecular biology and pharmacology of histamine receptor subtypes. Clin Neuropharmacol. 1992; 15 Suppl 1 Pt A:149A-150A. Ruat M, Traiffort E, Leurs R, Arrang JM, Kouyoumdjian G, Tardivel-Lacombe J, Piomelli D, Diaz G, Schwartz JC. PMID: 1498787.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    408. Dopamine activation of the arachidonic acid cascade as a basis for D1/D2 receptor synergism. Nature. 1991 Sep 12; 353(6340):164-7. Piomelli D, Pilon C, Giros B, Sokoloff P, Martres MP, Schwartz JC. PMID: 1909771.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    409. Bidirectional control of phospholipase A2 activity by Ca2+/calmodulin-dependent protein kinase II, cAMP-dependent protein kinase, and casein kinase II. Proc Natl Acad Sci U S A. 1991 Aug 01; 88(15):6770-4. Piomelli D, Greengard P. PMID: 1650481; PMCID: PMC52170.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    410. Metabolism of arachidonic acid in nervous system of marine mollusk Aplysia californica. Am J Physiol. 1991 May; 260(5 Pt 2):R844-8. Piomelli D. PMID: 1903603.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    411. A phospholipase A2-stimulating protein regulated by protein kinase C in Aplysia neurons. Brain Res Mol Brain Res. 1991 Mar; 9(4):347-51. Calignano A, Piomelli D, Sacktor TC, Schwartz JH. PMID: 1645437.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    412. Lipoxygenase metabolites of arachidonic acid in neuronal transmembrane signalling. Trends Pharmacol Sci. 1990 Sep; 11(9):367-73. Piomelli D, Greengard P. PMID: 2122564.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    413. Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites. Proc Natl Acad Sci U S A. 1989 Nov; 86(21):8550-4. Piomelli D, Wang JK, Sihra TS, Nairn AC, Czernik AJ, Greengard P. PMID: 2554319; PMCID: PMC298320.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    414. Formation and action of 8-hydroxy-11,12-epoxy-5,9,14-icosatrienoic acid in Aplysia: a possible second messenger in neurons. Proc Natl Acad Sci U S A. 1989 Mar; 86(5):1721-5. Piomelli D, Shapiro E, Zipkin R, Schwartz JH, Feinmark SJ. PMID: 2493649; PMCID: PMC286773.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    415. 12-keto-eicosatetraenoic acid. A biologically active eicosanoid in the nervous system of Aplysia. Ann N Y Acad Sci. 1989; 559:208-18. Piomelli D, Feinmark SJ, Shapiro E, Schwartz JH. PMID: 2774398.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    416. Biologically active metabolites of the 12-lipoxygenase pathway are formed by Aplysia nervous tissue. Ann N Y Acad Sci. 1989; 559:121-30. Feinmark SJ, Piomelli D, Shapiro E, Schwartz JH. PMID: 2505651.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    417. Formation and biological activity of 12-ketoeicosatetraenoic acid in the nervous system of Aplysia. J Biol Chem. 1988 Nov 15; 263(32):16591-6. Piomelli D, Feinmark SJ, Shapiro E, Schwartz JH. PMID: 3182804.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    418. The role of arachidonic acid metabolites in signal transduction in an identified neural network mediating presynaptic inhibition in Aplysia. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 1:425-33. Shapiro E, Piomelli D, Feinmark S, Vogel S, Chin G, Schwartz JH. PMID: 3151176.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    419. Metabolites of arachidonic acid in the nervous system of Aplysia: possible mediators of synaptic modulation. J Neurosci. 1987 Nov; 7(11):3675-86. Piomelli D, Shapiro E, Feinmark SJ, Schwartz JH. PMID: 3119791; PMCID: PMC6569051.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    420. Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells. Nature. 1987 Jul 2-8; 328(6125):38-43. Piomelli D, Volterra A, Dale N, Siegelbaum SA, Kandel ER, Schwartz JH, Belardetti F. PMID: 2439918.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    421. Leukotriene biosynthesis by canine and human coronary arteries. J Pharmacol Exp Ther. 1987 Jun; 241(3):763-70. Piomelli D, Feinmark SJ, Cannon PJ. PMID: 3598901.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    422. Antagonistic actions of prostaglandins E2 and F2 alpha on the isolated lungs of the frog, Rana esculenta L. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1987; 87(1):21-2. Piomelli D, Pinto A, Sannino C, Tota B. PMID: 2885133.
      View in: PubMed   Mentions: Translation:Animals
    423. Leukotrienes in teleost fish gills. Naturwissenschaften. 1985 May; 72(5):276-7. Piomelli D. PMID: 18443728.
      View in: PubMed   Mentions: 1     Fields:    
    424. The cyclo-oxygenase pathway in the avascular heart of the frog, Rana esculenta L. Gen Pharmacol. 1984; 15(4):309-13. Ghiara P, Parente L, Piomelli D. PMID: 6436138.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    425. Vasoconstrictory effects of adrenalin on the perfused head of the eel (Anguilla anguilla L.). Comp Biochem Physiol C Comp Pharmacol Toxicol. 1983; 76(1):209-13. Pinto A, Piomelli D. PMID: 6139251.
      View in: PubMed   Mentions: Translation:Animals
    426. Different distribution of serotonin in an elasmobranch (Scyliorhinus stellaris) and in a teleost (Conger conger) fish. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1983; 74(1):139-42. Piomelli D, Tota B. PMID: 6132758.
      View in: PubMed   Mentions: 4  Translation:Animals
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