David Kevin Imagawa

Title(s)Clinical Professor, Surgery
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-3884
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Novel combination approaches to locoregional and systemic therapy in the management of primary and metastatic liver tumors. Clin Adv Hematol Oncol. 2023 Dec; 21(12):633-643. Dai M, Tiu BY, Chen M, Sing C, Sharma V, Hoyos JP, Scherr R, Lin WJ, Breuer JA, Dayyani F, Imagawa D, Abi-Jaoudeh N. PMID: 38039057.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Drug-Eluting Embolic Loaded with Tyrosine Kinase Inhibitor Targeted Therapies for Transarterial Chemoembolization in a VX2 Model. Cancers (Basel). 2023 Jun 18; 15(12). Abi-Jaoudeh N, Sadeghi B, Javan H, Na J, Beaton G, Tucci F, Ravula S, Imagawa DK. PMID: 37370846; PMCID: PMC10296897.
      View in: PubMed   Mentions:
    3. Targeting Hypoxia-Inducible Factor-1α for the Management of Hepatocellular Carcinoma. Cancers (Basel). 2023 May 12; 15(10). Huynh KN, Rao S, Roth B, Bryan T, Fernando DM, Dayyani F, Imagawa D, Abi-Jaoudeh N. PMID: 37345074; PMCID: PMC10216171.
      View in: PubMed   Mentions: 7  
    4. Delayed gastric emptying is associated with increased risk of mortality in patients undergoing pancreaticoduodenectomy for pancreatic adenocarcinoma. Updates Surg. 2023 Apr; 75(3):523-530. Dominguez OH, Grigorian A, Wolf RF, Imagawa DK, Nahmias JT, Jutric Z. PMID: 36309940; PMCID: PMC10042927.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    5. Intra-Operative Abdominal Drain Placement for Gallbladder Cancer Surgery and Risk of Infectious Complications. Surg Infect (Larchmt). 2022 Feb; 23(1):22-28. Hasjim BJ, Grigorian A, Jutric Z, Wolf RF, Yamamoto M, Imagawa DK, Nahmias J. PMID: 34494909.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Phase I Trial on Arterial Embolization with Hypoxia Activated Tirapazamine for Unresectable Hepatocellular Carcinoma. J Hepatocell Carcinoma. 2021; 8:421-434. Abi-Jaoudeh N, Dayyani F, Chen PJ, Fernando D, Fidelman N, Javan H, Liang PC, Hwang JI, Imagawa DK. PMID: 34041204; PMCID: PMC8139681.
      View in: PubMed   Mentions: 13  Translation:CTClinical Trials
    7. Spontaneous choledochoduodenal fistula in a patient with a bile duct injury following laparoscopic cholecystectomy. J Surg Case Rep. 2019 May; 2019(5):rjz141. Gallagher SP, Imagawa DK. PMID: 31086653; PMCID: PMC6507672.
      View in: PubMed   Mentions: 4  
    8. Perioperative blood transfusion is associated with an increased risk for post-surgical infection following pancreaticoduodenectomy. HPB (Oxford). 2019 11; 21(11):1577-1584. Dosch AR, Grigorian A, Delaplain PT, Bartholomew TS, Won EJ, Gabriel V, Wolf RF, Jutric Z, Imagawa DK. PMID: 31040065.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    9. Bile Metabolism and Lithogenesis: An Update. Surg Clin North Am. 2019 Apr; 99(2):215-229. Dosch AR, Imagawa DK, Jutric Z. PMID: 30846031.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    10. Significance and Prevalence of Haziness Surrounding the Hepatic Artery and Celiac Axis on Computed Tomographic Imaging After Pancreaticoduodenectomy. J Comput Assist Tomogr. 2018 Jul/Aug; 42(4):637-641. Liu H, Imagawa D, Ward G, Dullet N, Lall C. PMID: 29489592.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Systematic review of islet cryopreservation. Islets. 2018 01 02; 10(1):40-49. Kojayan GG, Alexander M, Imagawa DK, Lakey JRT. PMID: 29315020; PMCID: PMC5800373.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    12. Development of Postoperative Diabetes Mellitus in Patients Undergoing Distal Pancreatectomy versus Whipple Procedure. Am Surg. 2017 Oct 01; 83(10):1050-1053. Nguyen A, Demirjian A, Yamamoto M, Hollenbach K, Imagawa DK. PMID: 29391093.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Efficacy of Negative Pressure Wound Treatment in Preventing Surgical Site Infections after Whipple Procedures. Am Surg. 2017 Oct 01; 83(10):1166-1169. Gupta R, Darby GC, Imagawa DK. PMID: 29391117.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    14. A case report on a rare anatomic variant of cystic duct insertion. J Surg Case Rep. 2017 Jul; 2017(7):rjx131. Yu JJ, Morell M, Lee JG, Imagawa DK. PMID: 28721192; PMCID: PMC5508545.
      View in: PubMed   Mentions:
    15. Management of an Accessory Bile Duct Leak Following Pancreaticoduodenectomy: A Novel Approach Utilizing a Percutaneous and Endoscopic Rendezvous. ACG Case Rep J. 2017; 4:e2. Rapp GA, Nelson KJ, Imagawa DK, Huang JY, Lee JG. PMID: 28138446; PMCID: PMC5244888.
      View in: PubMed   Mentions:
    16. Global Estimation of Surgical Procedures Needed for Forcibly Displaced Persons. World J Surg. 2016 Nov; 40(11):2628-2634. Zha Y, Stewart B, Lee E, Remick KN, Rothstein DH, Groen RS, Burnham G, Imagawa DK, Kushner AL. PMID: 27225996.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    17. Total pancreatectomy and islet autotransplantation: A decade nationwide analysis. World J Transplant. 2016 Mar 24; 6(1):233-8. Fazlalizadeh R, Moghadamyeghaneh Z, Demirjian AN, Imagawa DK, Foster CE, Lakey JR, Stamos MJ, Ichii H. PMID: 27011922; PMCID: PMC4801800.
      View in: PubMed   Mentions: 8  
    18. Evolution in the Treatment of Delayed Postpancreatectomy Hemorrhage: Surgery to Interventional Radiology. Pancreas. 2015 Aug; 44(6):953-8. Khalsa BS, Imagawa DK, Chen JI, Dermirjian AN, Yim DB, Findeiss LK. PMID: 25906453.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    19. Perioperative goal-directed therapy and postoperative outcomes in patients undergoing high-risk abdominal surgery: a historical-prospective, comparative effectiveness study. Crit Care. 2015 Jun 19; 19:261. Cannesson M, Ramsingh D, Rinehart J, Demirjian A, Vu T, Vakharia S, Imagawa D, Yu Z, Greenfield S, Kain Z. PMID: 26088649; PMCID: PMC4512146.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    20. Closed-loop assisted versus manual goal-directed fluid therapy during high-risk abdominal surgery: a case-control study with propensity matching. Crit Care. 2015 Mar 19; 19:94. Rinehart J, Lilot M, Lee C, Joosten A, Huynh T, Canales C, Imagawa D, Demirjian A, Cannesson M. PMID: 25888403; PMCID: PMC4372998.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    21. Composite liver tumors: a radiologic-pathologic correlation. Clin Mol Hepatol. 2014 Dec; 20(4):406-10. Nayyar M, Imagawa DK, Tirkes T, Demirjian AN, Houshyar R, Sandrasegaran K, Nangia CS, Seery T, Bhargava P, Choi JI, Lall C. PMID: 25548749; PMCID: PMC4278074.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Vascular reconstruction plays an important role in the treatment of pancreatic adenocarcinoma. J Vasc Surg. 2015 Feb; 61(2):475-80. Sgroi MD, Narayan RR, Lane JS, Demirjian A, Kabutey NK, Fujitani RM, Imagawa DK. PMID: 25441672.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    23. Magnetic resonance imaging following treatment of advanced hepatocellular carcinoma with sorafenib. Clin Mol Hepatol. 2014 Jun; 20(2):218-22. Choi JI, Imagawa DK, Bhosale P, Bhargava P, Tirkes T, Seery TE, Lall C. PMID: 25032190; PMCID: PMC4099339.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    24. Advances in managing hepatocellular carcinoma. Front Med. 2014 Jun; 8(2):175-89. Reataza M, Imagawa DK. PMID: 24810646.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    25. Surgery for gallstone ileus: a nationwide comparison of trends and outcomes. Ann Surg. 2014 Feb; 259(2):329-35. Halabi WJ, Kang CY, Ketana N, Lafaro KJ, Nguyen VQ, Stamos MJ, Imagawa DK, Demirjian AN. PMID: 23295322.
      View in: PubMed   Mentions: 96     Fields:    Translation:Humans
    26. Massive congenital choledocal cyst. Liver Int. 2014 Jul; 34(6):e161. Tracy LE, Imagawa DK. PMID: 24330383.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    27. Metastatic lesions to the liver. Int J Hepatol. 2013; 2013:104365. Ortiz J, Imagawa DK, Verzaro R, Serafini F, Kayler LK. PMID: 24349791; PMCID: PMC3855981.
      View in: PubMed   Mentions:
    28. Giant choledochal cyst mimicking massive gallbladder hydrops in an adult patient: multi detector computed tomography and magnetic resonance imaging findings correlated to gross and histopathological findings. J Clin Imaging Sci. 2013; 3:45. Choi JI, Lall C, Bhargava P, Imagawa DK. PMID: 24228213; PMCID: PMC3823391.
      View in: PubMed   Mentions: 2  
    29. Validation of revised American Joint Committee on Cancer staging for gallbladder cancer based on a single institution experience. Am Surg. 2013 Oct; 79(10):1045-9. Koh CY, Demirjian AN, Chen WP, McLaren CE, Imagawa DK. PMID: 24160796; PMCID: PMC4017658.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    30. Gd-EOB-DTPA-Enhanced MRI for Detection of Liver Metastases from Colorectal Cancer: A Surgeon's Perspective! Int J Hepatol. 2013; 2013:572307. Lafaro KJ, Roumanis P, Demirjian AN, Lall C, Imagawa DK. PMID: 23653860; PMCID: PMC3638698.
      View in: PubMed   Mentions: 8  
    31. Limited utility of plain abdominal radiographs in evaluating intussusceptions secondary to long indwelling feeding tubes. J Clin Imaging Sci. 2013; 3:9. Yang A, Lall C, Bhargava P, Imagawa D. PMID: 23607078; PMCID: PMC3625884.
      View in: PubMed   Mentions:
    32. Pneumatosis in post-Whipple patients. Am Surg. 2012 Oct; 78(10):1105-8. Wikholm LI, Imagawa DK. PMID: 23025951.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Safety and efficacy of trans arterial chemoembolization with drug-eluting beads in hepatocellular cancer: a systematic review. Hepatogastroenterology. 2012 Jan-Feb; 59(113):255-60. Martin R, Geller D, Espat J, Kooby D, Sellars M, Goldstein R, Imagawa D, Scoggins C. PMID: 22251546.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    34. Endoscopic versus surgical treatment of downstream pancreatic duct stones in chronic pancreatitis. Am Surg. 2011 Nov; 77(11):1531-8. Hong J, Wang J, Keleman AM, Imagawa DK, Xu K, Wang W, Liu E, Niu W, Wang J, Sun Q, Wang J, Peng C, Zhao W, Niu J. PMID: 22196670.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    35. Clinical presentation of hepatocellular carcinoma (HCC) in Asian-Americans versus non-Asian-Americans. J Immigr Minor Health. 2011 Oct; 13(5):842-8. Wong PY, Xia V, Imagawa DK, Hoefs J, Hu KQ. PMID: 20890660; PMCID: PMC3155747.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    36. Associated vascular injury in patients with bile duct injury during cholecystectomy. Am Surg. 2011 Oct; 77(10):1330-3. Keleman AM, Imagawa DK, Findeiss L, Hanna MH, Tan VH, Katz MH, Goodwin SC, Lane JS, Vajgrt D, Nguyen T, Smith CW. PMID: 22127081.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    37. Phase IIA trial testing erlotinib as an intervention against intraductal pancreatic mucinous neoplasms. Cancer Prev Res (Phila). 2011 Apr; 4(4):512-3. Lipkin S, Lee J, Imagawa D, Hewitt SM, Tucker C, Zell JA, Wong V, Garcia A, Gonzalez R, Della Zanna G, Richmond E, Rodriguez LM, Bigg M, Schnoll-Sussmans F, Meyskens F. PMID: 21464031; PMCID: PMC4492452.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    38. Adenosquamous versus adenocarcinoma of the pancreas: a population-based outcomes analysis. J Gastrointest Surg. 2011 Jan; 15(1):165-74. Katz MH, Taylor TH, Al-Refaie WB, Hanna MH, Imagawa DK, Anton-Culver H, Zell JA. PMID: 21082275; PMCID: PMC3023036.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansPHPublic Health
    39. Surgical management of recurrent ovarian cancer: the advantage of collaborative surgical management and a multidisciplinary approach. Gynecol Oncol. 2011 Jan; 120(1):29-32. Burton E, Chase D, Yamamoto M, de Guzman J, Imagawa D, Berman ML. PMID: 21055797.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    40. Metronomic gemcitabine in combination with sunitinib inhibits multisite metastasis and increases survival in an orthotopic model of pancreatic cancer. Mol Cancer Ther. 2010 Jul; 9(7):2068-78. Tran Cao HS, Bouvet M, Kaushal S, Keleman A, Romney E, Kim G, Fruehauf J, Imagawa DK, Hoffman RM, Katz MH. PMID: 20606044; PMCID: PMC4383085.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    41. The clinical presentation of chronic hepatitis B virus infection in Asian Americans: a single center retrospective study. J Clin Gastroenterol. 2010 May-Jun; 44(5):364-70. Mellen JS, Xia VW, Hashemzadeh M, Imagawa D, Jamal M, Hoefs J, Hu KQ. PMID: 19770675.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    42. Use of Seamguard to prevent pancreatic leak following distal pancreatectomy. Arch Surg. 2009 Oct; 144(10):894-9. Yamamoto M, Hayashi MS, Nguyen NT, Nguyen TD, McCloud S, Imagawa DK. PMID: 19841355.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    43. Hepatitis B immunoglobulin in preventing reinfection following liver transplantation. Expert Rev Anti Infect Ther. 2009 Apr; 7(3):321-8. Yamamoto M, Little G, Imagawa DK. PMID: 19344245.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    44. Multidisciplinary management of resectable adenocarcinoma of the pancreatic head. Expert Rev Anticancer Ther. 2008 Oct; 8(10):1611-21. Yamamoto M, Imagawa DK, Katz MH. PMID: 18925853.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Use of Vascular Clamping in Hepatic Surgery: Lessons Learned From 1260 Liver Resections-Invited Critique. Arch Surg. 2008 Apr 01; 143(4):388. Imagawa DK. PMID: 28715573.
      View in: PubMed   Mentions:    Fields:    
    46. The influence of organ acceptance criteria on long-term graft survival: outcomes of a kidney transplant program. Am J Surg. 2008 Feb; 195(2):149-52. Foster CE, Weng RR, Smith CV, Imagawa DK. PMID: 18096123.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    47. Cystic pancreatic neoplasm in pregnancy: a case report and review of the literature. Arch Surg. 2008 Jan; 143(1):84-6. Wiseman JE, Yamamoto M, Nguyen TD, Bonadio J, Imagawa DK. PMID: 18209157.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    48. Endoscopic ultrasound-guided fine-needle aspiration of undifferentiated carcinoma with osteoclast-like giant cells of the pancreas: a report of 2 cases with literature review. Diagn Cytopathol. 2007 Sep; 35(9):601-6. Chopra S, Wu ML, Imagawa DK, Lee J, Gu M. PMID: 17703445.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    49. Argon beam coagulator for treatment of hepatic rupture with hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome. Obstet Gynecol. 2006 Feb; 107(2 Pt 2):525-6. Shrivastava VK, Imagawa D, Wing DA. PMID: 16449174.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    50. Laparoscopic distal pancreatic resection. Am Surg. 2005 Sep; 71(9):744-9. Root J, Nguyen N, Jones B, McCloud S, Lee J, Nguyen P, Chang K, Lin P, Imagawa D. PMID: 16468510.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    51. Potent farnesyltransferase inhibitor ABT-100 abrogates acute allograft rejection. J Heart Lung Transplant. 2005 Sep; 24(9):1403-9. Si MS, Ji P, Lee M, Kwok J, Kusumoto J, Naasz E, Ng SC, Imagawa DK. PMID: 16143263.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    52. Hepatic artery pseudoaneurysm: a report of seven cases and a review of the literature. Surg Today. 2005; 35(7):543-7. Finley DS, Hinojosa MW, Paya M, Imagawa DK. PMID: 15976950.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    53. Fatal variceal rupture after sildenafil use: report of a case. Curr Surg. 2005 Jan-Feb; 62(1):55-6. Finley DS, Lugo B, Ridgway J, Teng W, Imagawa DK. PMID: 15708146.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    54. Use of Yttrium-90 TheraSphere for the treatment of unresectable hepatocellular carcinoma. Am Surg. 2004 Nov; 70(11):947-53. Liu MD, Uaje MB, Al-Ghazi MS, Fields D, Herman J, Kuo JV, Milne N, Nguyen TH, Ramsinghani NS, Tokita KM, Tsai FY, Vajgrt DJ, Imagawa DK. PMID: 15586503.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    55. Prevalence of metastases in hepatocellular carcinoma: risk factors and impact on survival. Am Surg. 2003 Oct; 69(10):879-85. Si MS, Amersi F, Golish SR, Ortiz JA, Zaky J, Finklestein D, Busuttil RW, Imagawa DK. PMID: 14570367.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    56. Expression of Kit and platelet-derived growth factor receptors alpha and beta in cholangiocarcinoma, and case report of therapy with imatinib mesylate (STI571). Anticancer Drugs. 2003 Sep; 14(8):651-7. Holcombe RF, Gu M, Imagawa D, Milovanovic T. PMID: 14501388.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    57. Immunomodulatory effects of docetaxel on human lymphocytes. Invest New Drugs. 2003 Aug; 21(3):281-90. Si MS, Imagawa DK, Ji P, Wei X, Holm B, Kwok J, Lee M, Reitz BA, Borie DC. PMID: 14578678.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    58. Farnesyltransferase inhibition: a novel method of immunomodulation. Int Immunopharmacol. 2003 Apr; 3(4):475-83. Si MS, Ji P, Tromberg BJ, Lee M, Kwok J, Ng SC, Imagawa DK. PMID: 12689653.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    59. Carcinoid tumors of the common bile duct: report of two cases. Surg Today. 2003; 33(7):553-5. Podnos YD, Jimenez JC, Zainabadi K, Ji P, Cooke J, Busuttil RW, Imagawa DK. PMID: 14507005.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    60. Prevention of chronic rejection by pravastatin in a rat kidney transplant model. Transplantation. 2002 Sep 27; 74(6):821-7. Ji P, Si MS, Podnos Y, Chow H, Steward E, Imagawa DK. PMID: 12364863.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
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