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Molloi, Sabee

TitleProfessor
InstitutionUniversity of California, Irvine
DepartmentRadiological Sciences
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-5904, 7854
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    Collapse Research 
    Collapse Research Activities and Funding
    Multiethnic Study of Breast Arterial Calcium Gradation and CVD
    NIH/NHLBI R01HL106043Sep 12, 2011 - Apr 30, 2016
    Role: Co-Principal Investigator
    Fractional flow reserve measurement based on coronary angiographic images
    NIH/NHLBI R01HL089941Jul 1, 2009 - Jun 30, 2012
    Role: Principal Investigator
    Quantification of breast density using dual energy mammography
    NIH/NCI R01CA136871May 24, 2009 - Apr 30, 2014
    Role: Principal Investigator
    Quantification of coronary calcium mass by dual energy fluoroscopy
    NIH/NHLBI R01HL083295Aug 1, 2007 - Jun 30, 2012
    Role: Principal Investigator
    X-ray imaging using edge-on-microchannel plate detectors
    NIH/NIBIB R01EB000514Jul 1, 2003 - Apr 30, 2008
    Role: Principal Investigator
    Quantification of Regional coronary Blood Flow
    NIH/NHLBI R01HL067159May 1, 2001 - Apr 30, 2005
    Role: Principal Investigator
    AREA BEAM EQUALIZATION FOR X-RAY ANGIOGRAPHY
    NIH/NHLBI R01HL057338Jul 15, 1997 - Jun 30, 2002
    Role: Principal Investigator
    PHASIC CORONARY FLOW MEASUREMENT BY DUAL-ENERGY DSA
    NIH/NHLBI R01HL048030Jan 1, 1993 - Dec 31, 1997
    Role: Principal Investigator
    QUANTITATIVE CORONARY ANGIOGRAPHY BY DUAL ENERGY DSA
    NIH/NHLBI R29HL042435Apr 1, 1989 - Mar 31, 1994
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Molloi S, Johnson T, Lipinski J, Ding H, Hubbard L. A phantom based evaluation of vessel lumen area quantification for coronary CT angiography. Int J Cardiovasc Imaging. 2018 Sep 08. PMID: 30196453.
      View in: PubMed
    2. Hubbard L, Malkasian S, Zhao Y, Abbona P, Molloi S. Contrast-to-Noise Ratio Optimization in Coronary Computed Tomography Angiography: Validation in a Swine Model. Acad Radiol. 2018 Aug 29. PMID: 30172714.
      View in: PubMed
    3. Malkasian S, Hubbard L, Dertli B, Kwon J, Molloi S. Quantification of vessel-specific coronary perfusion territories using minimum-cost path assignment and computed tomography angiography: Validation in a swine model. J Cardiovasc Comput Tomogr. 2018 Jun 18. PMID: 30042078.
      View in: PubMed
    4. Iribarren C, Sanchez G, Husson G, Levine-Hall T, Quesenberry C, Sam DL, Maier J, Chaudhary RS, Patel M, Sadeghi B, Javan H, Cho HM, Ding H, Molloi S. MultIethNic Study of BrEast ARterial Calcium Gradation and CardioVAscular Disease: cohort recruitment and baseline characteristics. Ann Epidemiol. 2018 Jan; 28(1):41-47.e12. PMID: 29246501.
      View in: PubMed
    5. Hubbard L, Lipinski J, Ziemer B, Malkasian S, Sadeghi B, Javan H, Groves EM, Dertli B, Molloi S. Comprehensive Assessment of Coronary Artery Disease by Using First-Pass Analysis Dynamic CT Perfusion: Validation in a Swine Model. Radiology. 2018 01; 286(1):93-102. PMID: 29059038.
      View in: PubMed
    6. Ding H, Molloi S. Quantitative contrast-enhanced spectral mammography based on photon-counting detectors: A feasibility study. Med Phys. 2017 Aug; 44(8):3939-3951. PMID: 28432828.
      View in: PubMed
    7. Johansson H, von Tiedemann M, Erhard K, Heese H, Ding H, Molloi S, Fredenberg E. Breast-density measurement using photon-counting spectral mammography. Med Phys. 2017 Jul; 44(7):3579-3593. PMID: 28421611.
      View in: PubMed
    8. Wang J, Ding H, Bidgoli FA, Zhou B, Iribarren C, Molloi S, Baldi P. Detecting Cardiovascular Disease from Mammograms With Deep Learning. IEEE Trans Med Imaging. 2017 05; 36(5):1172-1181. PMID: 28113340.
      View in: PubMed
    9. Hubbard L, Ziemer B, Lipinski J, Sadeghi B, Javan H, Groves EM, Malkasian S, Molloi S. Functional Assessment of Coronary Artery Disease Using Whole-Heart Dynamic Computed Tomographic Perfusion. Circ Cardiovasc Imaging. 2016 Dec; 9(12). PMID: 27956409.
      View in: PubMed
    10. Molloi S, Johnson T, Ding H, Lipinski J. Accurate quantification of vessel cross-sectional area using CT angiography: a simulation study. Int J Cardiovasc Imaging. 2017 Mar; 33(3):411-419. PMID: 27838897.
      View in: PubMed
    11. Ding H, Sennung D, Cho HM, Molloi S. Quantification of breast lesion compositions using low-dose spectral mammography: A feasibility study. Med Phys. 2016 Oct; 43(10):5527. PMID: 27782705.
      View in: PubMed
    12. Liu J, Ding H, Molloi S, Zhang X, Gao H. TICMR: Total Image Constrained Material Reconstruction via Nonlocal Total Variation Regularization for Spectral CT. IEEE Trans Med Imaging. 2016 12; 35(12):2578-2586. PMID: 27392346.
      View in: PubMed
    13. Ziemer BP, Hubbard L, Lipinski J, Molloi S. Dynamic CT perfusion measurement in a cardiac phantom. Int J Cardiovasc Imaging. 2015 Oct; 31(7):1451-9. PMID: 26156231.
      View in: PubMed
    14. Cho HM, Ding H, Barber WC, Iwanczyk JS, Molloi S. Microcalcification detectability using a bench-top prototype photon-counting breast CT based on a Si strip detector. Med Phys. 2015 Jul; 42(7):4401-10. PMID: 26133636; PMCID: PMC4491016.
    15. Molloi S, Ding H, Feig S. Breast density evaluation using spectral mammography, radiologist reader assessment, and segmentation techniques: a retrospective study based on left and right breast comparison. Acad Radiol. 2015 Aug; 22(8):1052-9. PMID: 26031229; PMCID: PMC4515382.
    16. Ding H, Cho HM, Barber WC, Iwanczyk JS, Molloi S. Characterization of energy response for photon-counting detectors using x-ray fluorescence. Med Phys. 2014 Dec; 41(12):121902. PMID: 25471962; PMCID: PMC4235650.
    17. Zhang Z, Chen J, Takarada S, Molloi S. Determination of culprit coronary artery branches using hemodynamic indices from angiographic images. Int J Cardiovasc Imaging. 2015 Jan; 31(1):11-9. PMID: 25288357.
      View in: PubMed
    18. Ding H, Zhao B, Baturin P, Behroozi F, Molloi S. Breast tissue decomposition with spectral distortion correction: a postmortem study. Med Phys. 2014 Oct; 41(10):101901. PMID: 25281953; PMCID: PMC4281076.
    19. Ding H, Gao H, Zhao B, Cho HM, Molloi S. A high-resolution photon-counting breast CT system with tensor-framelet based iterative image reconstruction for radiation dose reduction. Phys Med Biol. 2014 Oct 21; 59(20):6005-17. PMID: 25230204.
      View in: PubMed
    20. Cho HM, Barber WC, Ding H, Iwanczyk JS, Molloi S. Characteristic performance evaluation of a photon counting Si strip detector for low dose spectral breast CT imaging. Med Phys. 2014 Sep; 41(9):091903. PMID: 25186390; PMCID: PMC4137870.
    21. Molloi S, Ducote JL, Ding H, Feig SA. Postmortem validation of breast density using dual-energy mammography. Med Phys. 2014 Aug; 41(8):081917. PMID: 25086548; PMCID: PMC4119195.
    22. Lam AR, Ding H, Molloi S. Quantification of breast density using dual-energy mammography with liquid phantom calibration. Phys Med Biol. 2014 Jul 21; 59(14):3985-4000. PMID: 24971873.
      View in: PubMed
    23. Ding H, Klopfer MJ, Ducote JL, Masaki F, Molloi S. Breast tissue characterization with photon-counting spectral CT imaging: a postmortem breast study. Radiology. 2014 Sep; 272(3):731-8. PMID: 24814180; PMCID: PMC4263620.
    24. Chalyan DA, Zhang Z, Takarada S, Molloi S. End-diastolic fractional flow reserve: comparison with conventional full-cardiac cycle fractional flow reserve. Circ Cardiovasc Interv. 2014 Feb; 7(1):28-34. PMID: 24496240.
      View in: PubMed
    25. Alivov Y, Baturin P, Le HQ, Ducote J, Molloi S. Optimization of K-edge imaging for vulnerable plaques using gold nanoparticles and energy resolved photon counting detectors: a simulation study. Phys Med Biol. 2014 Jan 06; 59(1):135-52. PMID: 24334301; PMCID: PMC3962835.
    26. Johnson T, Ding H, Le HQ, Ducote JL, Molloi S. Breast density quantification with cone-beam CT: a post-mortem study. Phys Med Biol. 2013 Dec 07; 58(23):8573-91. PMID: 24254317; PMCID: PMC3904793.
    27. Ding H, Johnson T, Lin M, Le HQ, Ducote JL, Su MY, Molloi S. Breast density quantification using magnetic resonance imaging (MRI) with bias field correction: a postmortem study. Med Phys. 2013 Dec; 40(12):122305. PMID: 24320536; PMCID: PMC3862600.
    28. Alivov Y, Molloi S. Performance of a hybrid pyroelectric LiNbO3 and TiO2 nanotubes X-ray source. Rev Sci Instrum. 2013 Jul; 84(7):073301. PMID: 23902052.
      View in: PubMed
    29. Alivov Y, Grant T, Capan C, Iwamoto W, Pagliuso PG, Molloi S. Origin of magnetism in undoped TiO2 nanotubes. Nanotechnology. 2013 Jul 12; 24(27):275704. PMID: 23764755.
      View in: PubMed
    30. Ding H, Ducote JL, Molloi S. Measurement of breast tissue composition with dual energy cone-beam computed tomography: a postmortem study. Med Phys. 2013 Jun; 40(6):061902. PMID: 23718593; PMCID: PMC3663856.
    31. Zhang Z, Molloi S. A novel angiographic fractional flow reserve. Reply. Am J Physiol Heart Circ Physiol. 2013 Apr 15; 304(8):H1176-7. PMID: 23589447.
      View in: PubMed
    32. Zhao B, Gao H, Ding H, Molloi S. Tight-frame based iterative image reconstruction for spectral breast CT. Med Phys. 2013 Mar; 40(3):031905. PMID: 23464320; PMCID: PMC3585830.
    33. Iribarren C, Molloi S. Breast Arterial Calcification: a New Marker of Cardiovascular Risk? Curr Cardiovasc Risk Rep. 2013 Apr; 7(2):126-135. PMID: 23538556.
      View in: PubMed
    34. Alivov Y, Feng J, Molloi S. Design of TiO_{2} nanotube based X-ray tube with single focusing electrode. J Xray Sci Technol. 2013; 21(4):567-77. PMID: 24191993.
      View in: PubMed
    35. Zhao B, Ding H, Lu Y, Wang G, Zhao J, Molloi S. Dual-dictionary learning-based iterative image reconstruction for spectral computed tomography application. Phys Med Biol. 2012 Dec 21; 57(24):8217-29. PMID: 23192234; PMCID: PMC4511115.
    36. Takarada S, Zhang Z, Molloi S. An angiographic technique for coronary fractional flow reserve measurement: in vivo validation. Int J Cardiovasc Imaging. 2013 Mar; 29(3):535-44. PMID: 22936416; PMCID: PMC3548942.
    37. Ding H, Molloi S. Quantification of breast density with spectral mammography based on a scanned multi-slit photon-counting detector: a feasibility study. Phys Med Biol. 2012 Aug 07; 57(15):4719-38. PMID: 22771941; PMCID: PMC3478949.
    38. Baturin P, Alivov Y, Molloi S. Spectral CT imaging of vulnerable plaque with two independent biomarkers. Phys Med Biol. 2012 Jul 07; 57(13):4117-38. PMID: 22683885.
      View in: PubMed
    39. Zhang Z, Takarada S, Molloi S. Quantification of absolute coronary flow reserve and relative fractional flow reserve in a swine animal model using angiographic image data. Am J Physiol Heart Circ Physiol. 2012 Aug 01; 303(3):H401-10. PMID: 22661513; PMCID: PMC3423159.
    40. Ding H, Molloi S. Image-based spectral distortion correction for photon-counting x-ray detectors. Med Phys. 2012 Apr; 39(4):1864-76. PMID: 22482608; PMCID: PMC3316693.
    41. Ding H, Ducote JL, Molloi S. Breast composition measurement with a cadmium-zinc-telluride based spectral computed tomography system. Med Phys. 2012 Mar; 39(3):1289-97. PMID: 22380361; PMCID: PMC3292597.
    42. Zhang Z, Takarada S, Molloi S. Assessment of coronary microcirculation in a swine animal model. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H402-8. PMID: 21622826; PMCID: PMC3154662.
    43. Lu X, Dang CQ, Guo X, Molloi S, Wassall CD, Kemple MD, Kassab GS. Elevated oxidative stress and endothelial dysfunction in right coronary artery of right ventricular hypertrophy. J Appl Physiol (1985). 2011 Jun; 110(6):1674-81. PMID: 21415175; PMCID: PMC3119132.
    44. Zhang Z, Takarada S, Molloi S. Quantification of coronary microvascular resistance using angiographic images for volumetric blood flow measurement: in vivo validation. Am J Physiol Heart Circ Physiol. 2011 Jun; 300(6):H2096-104. PMID: 21398596; PMCID: PMC3119091.
    45. Xu T, Ducote JL, Wong JT, Molloi S. Dynamic dual-energy chest radiography: a potential tool for lung tissue motion monitoring and kinetic study. Phys Med Biol. 2011 Feb 21; 56(4):1191-205. PMID: 21285477; PMCID: PMC3164987.
    46. Molloi S, Chalyan D, Le H, Wong JT. Estimation of coronary artery hyperemic blood flow based on arterial lumen volume using angiographic images. Int J Cardiovasc Imaging. 2012 Jan; 28(1):1-11. PMID: 21213052; PMCID: PMC3094746.
    47. Wong JT, Le H, Suh WM, Chalyan DA, Mehraien T, Kern MJ, Kassab GS, Molloi S. Quantification of fractional flow reserve based on angiographic image data. Int J Cardiovasc Imaging. 2012 Jan; 28(1):13-22. PMID: 21213051; PMCID: PMC3094747.
    48. Le HQ, Molloi S. Segmentation and quantification of materials with energy discriminating computed tomography: a phantom study. Med Phys. 2011 Jan; 38(1):228-37. PMID: 21361191; PMCID: PMC3021555.
    49. Le Huy Q, Molloi S. Least squares parameter estimation methods for material decomposition with energy discriminating detectors. Med Phys. 2011 Jan; 38(1):245-55. PMID: 21361193; PMCID: PMC3021557.
    50. Alivov Y, Klopfer M, Molloi S. Effect of TiO2 nanotube parameters on field emission properties. Nanotechnology. 2010 Dec 17; 21(50):505706. PMID: 21098943.
      View in: PubMed
    51. Le Huy Q, Ducote JL, Molloi S. Radiation dose reduction using a CdZnTe-based computed tomography system: comparison to flat-panel detectors. Med Phys. 2010 Mar; 37(3):1225-36. PMID: 20384260; PMCID: PMC2842286.
    52. Ducote JL, Molloi S. Quantification of breast density with dual energy mammography: an experimental feasibility study. Med Phys. 2010 Feb; 37(2):793-801. PMID: 20229889; PMCID: PMC2826385.
    53. Molloi S, Mehraien T, Iribarren C, Smith C, Ducote JL, Feig SA. Reproducibility of breast arterial calcium mass quantification using digital mammography. Acad Radiol. 2009 Mar; 16(3):275-82. PMID: 19201356; PMCID: PMC2664654.
    54. Ducote JL, Molloi S. Quantification of breast density with dual energy mammography: a simulation study. Med Phys. 2008 Dec; 35(12):5411-8. PMID: 19175100; PMCID: PMC2736719.
    55. Wong JT, Molloi S. Determination of fractional flow reserve (FFR) based on scaling laws: a simulation study. Phys Med Biol. 2008 Jul 21; 53(14):3995-4011. PMID: 18596370.
      View in: PubMed
    56. Le H, Wong JT, Molloi S. Estimation of regional myocardial mass at risk based on distal arterial lumen volume and length using 3D micro-CT images. Comput Med Imaging Graph. 2008 Sep; 32(6):488-501. PMID: 18595659; PMCID: PMC2613861.
    57. Molloi S, Xu T, Ducote J, Iribarren C. Quantification of breast arterial calcification using full field digital mammography. Med Phys. 2008 Apr; 35(4):1428-39. PMID: 18491538; PMCID: PMC2811554.
    58. Le HQ, Wong JT, Molloi S. Allometric scaling in the coronary arterial system. Int J Cardiovasc Imaging. 2008 Oct; 24(7):771-81. PMID: 18360777.
      View in: PubMed
    59. Wong JT, Kamyar F, Molloi S. Quantitative coronary angiography using image recovery techniques for background estimation in unsubtracted images. Med Phys. 2007 Oct; 34(10):4003-15. PMID: 17985646.
      View in: PubMed
    60. Molloi S, Wong JT. Regional blood flow analysis and its relationship with arterial branch lengths and lumen volume in the coronary arterial tree. Phys Med Biol. 2007 Mar 07; 52(5):1495-503. PMID: 17301467.
      View in: PubMed
    61. Ducote JL, Xu T, Molloi S. Dual-energy cardiac imaging: an image quality and dose comparison for a flat-panel detector and x-ray image intensifier. Phys Med Biol. 2007 Jan 07; 52(1):183-96. PMID: 17183135.
      View in: PubMed
    62. Xu T, Wong JT, Shikhaliev PM, Ducote JL, Al-Ghazi MS, Molloi S. Real-time tumor tracking using implanted positron emission markers: concept and simulation study. Med Phys. 2006 Jul; 33(7):2598-609. PMID: 16898464.
      View in: PubMed
    63. Ducote JL, Xu T, Molloi S. Optimization of a flat-panel based real time dual-energy system for cardiac imaging. Med Phys. 2006 Jun; 33(6):1562-8. PMID: 16872063.
      View in: PubMed
    64. Xu T, Ducote JL, Wong JT, Molloi S. Feasibility of real time dual-energy imaging based on a flat panel detector for coronary artery calcium quantification. Med Phys. 2006 Jun; 33(6):1612-22. PMID: 16872069.
      View in: PubMed
    65. Wong JT, Ducote JL, Xu T, Hassanein MT, Molloi S. Automated technique for angiographic determination of coronary blood flow and lumen volume. Acad Radiol. 2006 Feb; 13(2):186-94. PMID: 16428054.
      View in: PubMed
    66. Shikhaliev PM, Xu T, Ducote JL, Easwaramoorthy B, Mukherjee J, Molloi S. Positron autoradiography for intravascular imaging: feasibility evaluation. Phys Med Biol. 2006 Feb 21; 51(4):963-79. PMID: 16467590.
      View in: PubMed
    67. Movahed MR, Wong J, Molloi S. Removal of iodine contrast from coronary sinus in swine during coronary angiography. J Am Coll Cardiol. 2006 Jan 17; 47(2):465-7. PMID: 16412879.
      View in: PubMed
    68. Choy JS, Dang Q, Molloi S, Kassab GS. Nonuniformity of axial and circumferential remodeling of large coronary veins in response to ligation. Am J Physiol Heart Circ Physiol. 2006 Apr; 290(4):H1558-65. PMID: 16299258.
      View in: PubMed
    69. Shikhaliev PM, Xu T, Molloi S. Photon counting computed tomography: concept and initial results. Med Phys. 2005 Feb; 32(2):427-36. PMID: 15789589.
      View in: PubMed
    70. Wong J, Xu T, Husain A, Le H, Molloi S. Effect of area x-ray beam equalization on image quality and dose in digital mammography. Phys Med Biol. 2004 Aug 21; 49(16):3539-57. PMID: 15446786.
      View in: PubMed
    71. Xu T, Al-Ghazi MS, Molloi S. Treatment planning considerations of reshapeable automatic intensity modulator for intensity modulated radiation therapy. Med Phys. 2004 Aug; 31(8):2344-55. PMID: 15377101.
      View in: PubMed
    72. Molloi S, Zhou Y, Kassab GS. Regional volumetric coronary blood flow measurement by digital angiography: in vivo validation. Acad Radiol. 2004 Jul; 11(7):757-66. PMID: 15217593.
      View in: PubMed
    73. Shikhaliev PM, Xu T, Le H, Molloi S. Scanning-slit photon counting x-ray imaging system using a microchannel plate detector. Med Phys. 2004 May; 31(5):1061-71. PMID: 15191293.
      View in: PubMed
    74. Xu T, Shikhaliev PM, Berenji GR, Tehranzadeh J, Saremi F, Molloi S. Area beam equalization: optimization and performance of an automated prototype system for chest radiography. Acad Radiol. 2004 Apr; 11(4):377-89. PMID: 15109010.
      View in: PubMed
    75. Chen Z, Molloi S. Automatic 3D vascular tree construction in CT angiography. Comput Med Imaging Graph. 2003 Nov-Dec; 27(6):469-79. PMID: 14575780.
      View in: PubMed
    76. Molloi S, Dang Q, Breault J. Effect of vessel orientation on videodensitometry quantitative coronary arteriography. Med Phys. 2003 Nov; 30(11):2862-8. PMID: 14655932.
      View in: PubMed
    77. Hamza LH, Dang Q, Lu X, Mian A, Molloi S, Kassab GS. Effect of passive myocardium on the compliance of porcine coronary arteries. Am J Physiol Heart Circ Physiol. 2003 Aug; 285(2):H653-60. PMID: 12860566.
      View in: PubMed
    78. Molloi S, Berenji GR, Dang TT, Kassab G. Assessment of vasoreactivity using videodensitometry coronary angiography. Int J Cardiovasc Imaging. 2003 Aug; 19(4):271-9. PMID: 14598895.
      View in: PubMed
    79. Xu T, Le HQ, Molloi S. Patient-specific region-of-interest fluoroscopy device for X-ray dose reduction. Radiology. 2003 Feb; 226(2):585-92. PMID: 12563159.
      View in: PubMed
    80. Chen Z, Molloi S. Vascular tree object segmentation by deskeletonization of valley courses. Comput Med Imaging Graph. 2002 Nov-Dec; 26(6):419-28. PMID: 12453505.
      View in: PubMed
    81. Xu T, Shikhaliev PM, Al-Ghazi M, Molloi S. Reshapable physical modulator for intensity modulated radiation therapy. Med Phys. 2002 Oct; 29(10):2222-9. PMID: 12408295.
      View in: PubMed
    82. Zhou Y, Kassab GS, Molloi S. In vivo validation of the design rules of the coronary arteries and their application in the assessment of diffuse disease. Phys Med Biol. 2002 Mar 21; 47(6):977-93. PMID: 11936182.
      View in: PubMed
    83. Molloi S, Van Drie A, Wang F. X-ray beam equalization: feasibility and performance of an automated prototype system in a phantom and swine. Radiology. 2001 Dec; 221(3):668-75. PMID: 11719661.
      View in: PubMed
    84. Molloi S, Tang J, Mather T, Zhou Y. Area x-ray beam equalization for digital angiography. Med Phys. 1999 Dec; 26(12):2684-92. PMID: 10619254.
      View in: PubMed
    85. Molloi S, Zhou Y, Wamsely G. Scatter-glare estimation for digital radiographic systems: comparison of digital filtration and sampling techniques. IEEE Trans Med Imaging. 1998 Dec; 17(6):881-8. PMID: 10048845.
      View in: PubMed
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