Xiangmin Xu

Title(s)Professor, Anatomy and Neurobiology
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-0040
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    Collapse Research 
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    Customized cleared tissue light-sheet fluorescence microscope for imaging large brain samples
    NIH S10MH124715Sep 8, 2021 - Sep 7, 2022
    Role: Principal Investigator
    Comparative Single-Cell Epigenomic Analysis of AD-like Pathogenesis in Unconventional Animal Models
    NIH R24AG073198Sep 1, 2021 - May 31, 2025
    Role: Principal Investigator
    Engineered AAV vectors for combinatorial treatment of rare genetic brain diseases
    NIH R01FD007478Sep 1, 2021 - Aug 31, 2024
    Role: Principal Investigator
    Neural activity-dependent modulation of cortical microvascular restoration
    NIH R01NS121246Mar 15, 2021 - Dec 31, 2025
    Role: Principal Investigator
    Single-Cell Analysis of Aging-Associated 4D Nucleome in the Human Hippocampus
    NIH U01DA052769Sep 30, 2020 - Aug 31, 2025
    Role: Principal Investigator
    Neural circuit mechanisms underlying AD-related memory impairments
    NIH RF1AG065675Sep 11, 2020 - Aug 31, 2024
    Role: Principal Investigator
    Epigenomic analysis of neural circuits in Alzheimer's disease mouse models
    NIH R01AG067153Apr 15, 2020 - Mar 31, 2025
    Role: Principal Investigator
    Genetically engineered anterograde monosynaptic viral tracers for multi-species neural circuit analysis
    NIH RF1MH120020Aug 15, 2019 - Jul 31, 2022
    Role: Principal Investigator
    Reorganization of the Central Visual System by Inhibitory Neuron Transplantation
    NIH R01EY029490May 1, 2019 - Apr 30, 2024
    Role: Co-Principal Investigator
    Subiculm circuits for cortical feedback regulation of spatial mapping and learning
    NIH R01NS104897Dec 15, 2017 - Nov 30, 2022
    Role: Principal Investigator
    Neural circuit organization and function of the bed nucleus of the stria terminalis
    NIH R01MH113026Sep 15, 2017 - Jun 30, 2022
    Role: Principal Investigator
    Neuregulin-1 based molecular mechanisms of cortical plasticity
    NIH R01EY028212Sep 1, 2017 - May 31, 2021
    Role: Principal Investigator
    Disinhibition and experience-dependent visual plasticity
    NIH R01EY027407Jun 1, 2017 - May 31, 2021
    Role: Co-Principal Investigator
    High-resulution and cell-type-specific mapping of synaptic circuit organization in the bed nucleus of the stria terminalis
    NIH R21MH112085May 12, 2017 - Apr 30, 2019
    Role: Principal Investigator
    Inhibitory neuron circuit organization and function in prefrontal cortex.
    NIH R01MH105427Jul 6, 2015 - Mar 31, 2021
    Role: Principal Investigator
    Hippocampal inhibitory neuronal circuit organization
    NIH R01NS078434Sep 1, 2012 - May 31, 2018
    Role: Principal Investigator
    Local Connections and In Vivo Physiology of Inhibitory Cortical Neurons
    NIH R00DA023700Dec 1, 2006 - Sep 29, 2011
    Role: Principal Investigator
    Local Connections and In Vivo Physiology of Inhibitory Cortical Neurons
    NIH K99DA023700Dec 1, 2006 - Nov 30, 2008
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Meeting report for the 2024 UC Irvine Center for neural circuit mapping conference: Brain cell types, circuits, and disorders. Mol Psychiatry. 2025 Mar; 30(3):1256-1258. Grieco SF, Holmes TC, Xu X. PMID: 39384964.
      View in: PubMed   Mentions:    Fields:    
    2. Octodon degus laboratory colony management principles and methods for behavioral analysis for Alzheimer's disease neuroscience research. Front Aging Neurosci. 2024; 16:1517416. Garduño BM, Holmes TC, Deacon RMJ, Xu X, Cogram P. PMID: 39902280; PMCID: PMC11788410.
      View in: PubMed   Mentions:
    3. RegBoost: Enhancing mouse brain image registration using geometric priors and Laplacian interpolation. Neuroimage. 2025 Jan; 305:120981. Chilaparasetti AN, Thai A, Gao P, Xu X, Gopi M. PMID: 39732220.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    4. BDNF augmentation reverses cranial radiation therapy-induced cognitive decline and neurodegenerative consequences. Acta Neuropathol Commun. 2024 Dec 18; 12(1):190. El-Khatib SM, Vagadia AR, Le ACD, Baulch JE, Ng DQ, Du M, Johnston KG, Tan Z, Xu X, Chan A, Acharya MM. PMID: 39696694; PMCID: PMC11654382.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Projection-specific circuits of retrosplenial cortex with differential contributions to spatial cognition. Mol Psychiatry. 2024 Nov 07. Lin X, Ghafuri A, Chen X, Kazmi M, Nitz DA, Xu X. PMID: 39511453.
      View in: PubMed   Mentions:    Fields:    
    6. Small data methods in omics: the power of one. Nat Methods. 2024 Sep; 21(9):1597-1602. Johnston KG, Grieco SF, Nie Q, Theis FJ, Xu X. PMID: 39174710.
      View in: PubMed   Mentions:    Fields:    
    7. Miniaturized Head-Mount Doppler Optical Coherence Tomography Scope for Freely Moving Mouse. ACS Photonics. 2024 Aug 21; 11(8):3381-3389. Wang J, Ye Q, Chou L, Qiu S, Xu X, Chen Z. PMID: 39184188; PMCID: PMC11342407.
      View in: PubMed   Mentions:
    8. Single-cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer's risk gene mutation. Mol Psychiatry. 2025 Feb; 30(2):461-477. Johnston KG, Berackey BT, Tran KM, Gelber A, Yu Z, MacGregor GR, Mukamel EA, Tan Z, Green KN, Xu X. PMID: 39103533; PMCID: PMC11746152.
      View in: PubMed   Mentions: 4     Fields:    
    9. Brain image data processing using collaborative data workflows on Texera. Front Neural Circuits. 2024; 18:1398884. Ding Y, Huang Y, Gao P, Thai A, Chilaparasetti AN, Gopi M, Xu X, Li C. PMID: 39050044; PMCID: PMC11266044.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    10. Single-cell spatial transcriptomics reveals a dystrophic trajectory following a developmental bifurcation of myoblast cell fates in facioscapulohumeral muscular dystrophy. Genome Res. 2024 06 25; 34(5):665-679. Chen L, Kong X, Johnston KG, Mortazavi A, Holmes TC, Tan Z, Yokomori K, Xu X. PMID: 38777608; PMCID: PMC11216401.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. ULV: A robust statistical method for clustered data, with applications to multi-subject, single-cell omics data. ArXiv. 2024 Jun 10. Du M, Johnston K, Berrocal V, Li W, Xu X, Yu Z. PMID: 38947924; PMCID: PMC11213121.
      View in: PubMed   Mentions:
    12. Monosynaptic Rabies Tracing Reveals Sex- and Age-Dependent Dorsal Subiculum Connectivity Alterations in an Alzheimer's Disease Mouse Model. J Neurosci. 2024 Apr 17; 44(16). Ye Q, Gast G, Wilfley EG, Huynh H, Hays C, Holmes TC, Xu X. PMID: 38503494; PMCID: PMC11026364.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    13. Immunolabeling-compatible PEGASOS tissue clearing for high-resolution whole mouse brain imaging. Front Neural Circuits. 2024; 18:1345692. Gao P, Rivera M, Lin X, Holmes TC, Zhao H, Xu X. PMID: 38694272; PMCID: PMC11061518.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    14. Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI. NPJ Regen Med. 2024 Mar 18; 9(1):12. Nekanti U, Sakthivel PS, Zahedi A, Creasman DA, Nishi RA, Dumont CM, Piltti KM, Guardamondo GL, Hernandez N, Chen X, Song H, Lin X, Martinez J, On L, Lakatos A, Pawar K, David BT, Guo Z, Seidlits SK, Xu X, Shea LD, Cummings BJ, Anderson AJ. PMID: 38499577; PMCID: PMC10948859.
      View in: PubMed   Mentions:
    15. How the forebrain transitions to adulthood: developmental plasticity markers in a long-lived rodent reveal region diversity and the uniqueness of adolescence. Front Neurosci. 2024; 18:1365737. Garduño BM, Hanni P, Hays C, Cogram P, Insel N, Xu X. PMID: 38456144; PMCID: PMC10917993.
      View in: PubMed   Mentions:
    16. New rabies viral resources for multi-scale neural circuit mapping. Mol Psychiatry. 2024 Jul; 29(7):1951-1967. Bouin A, Wu G, Koyuncu OO, Ye Q, Kim KY, Wu MY, Tong L, Chen L, Phan S, Mackey MR, Ramachandra R, Ellisman MH, Holmes TC, Semler BL, Xu X. PMID: 38355784; PMCID: PMC11322437.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    17. Intranasal Delivery of Ketamine Induces Cortical Disinhibition. eNeuro. 2024 Jan; 11(1). Qiao X, Grieco SF, Yu Z, Holmes TC, Xu X. PMID: 38164560; PMCID: PMC10849039.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    18. Meeting report for the 2023 UC Irvine Center for Neural Circuit Mapping Conference: structure, function and development of neural circuits. Mol Psychiatry. 2024 01; 29(1):121-123. Grieco SF, Holmes TC, Xu X. PMID: 37919404; PMCID: PMC11089064.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    19. Single cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer's risk gene mutation. Res Sq. 2023 Dec 07. Johnston K, Berackey BB, Tran KM, Gelber A, Yu Z, MacGregor G, Mukamel EA, Tan Z, Green K, Xu X. PMID: 38106071; PMCID: PMC10723554.
      View in: PubMed   Mentions:
    20. Erythrocyte-brain endothelial interactions induce microglial responses and cerebral microhemorrhages in vivo. J Neuroinflammation. 2023 Nov 15; 20(1):265. Zhang H, Sumbria RK, Chang R, Sun J, Cribbs DH, Holmes TC, Fisher MJ, Xu X. PMID: 37968737; PMCID: PMC10647121.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    21. Monosynaptic rabies tracing maps inputs to CA1 cells in old AD model mice (APP-KI). Mol Psychiatry. 2023 Oct; 28(10):4021. Grieco SF, Holmes TC, Xu X. PMID: 38291104.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    22. Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI. Res Sq. 2023 Jul 19. Nekanti U, Sakthivel P, Zahedi A, Creasman DA, Nishi RA, Dumont CM, Piltti KM, Guardamondo GL, Hernandez N, Chen X, Song H, Lin X, Martinez J, On L, Lakatos A, Pawar K, David BT, Guo Z, Seidlits SK, Xu X, Shea LD, Cummings BJ, Anderson AJ. PMID: 37502943; PMCID: PMC10371146.
      View in: PubMed   Mentions:
    23. Anatomical and molecular characterization of parvalbumin-cholecystokinin co-expressing inhibitory interneurons: implications for neuropsychiatric conditions. Mol Psychiatry. 2023 Dec; 28(12):5293-5308. Grieco SF, Johnston KG, Gao P, Garduño BM, Tang B, Yi E, Sun Y, Horwitz GD, Yu Z, Holmes TC, Xu X. PMID: 37443194; PMCID: PMC11041731.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    24. Hippocampal CA3 inhibitory neurons receive extensive noncanonical synaptic inputs from CA1 and subicular complex. J Comp Neurol. 2023 09; 531(13):1333-1347. Lin X, Cyrus N, Avila B, Holmes TC, Xu X. PMID: 37312626; PMCID: PMC10525020.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    25. Anatomical organization of temporally correlated neural calcium activity in the hippocampal CA1 region. iScience. 2023 May 19; 26(5):106703. Chen L, Lin X, Ye Q, Nenadic Z, Holmes TC, Nitz DA, Xu X. PMID: 37250317; PMCID: PMC10214731.
      View in: PubMed   Mentions:
    26. Obtaining brain tissue from living patients for psychiatry research: collaboration with patients with epilepsy and neurosurgeons. Lancet Psychiatry. 2023 06; 10(6):381. Paff M, Grieco SF, Xu X. PMID: 37088087.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Probing neural circuit mechanisms in Alzheimer's disease using novel technologies. Mol Psychiatry. 2023 Oct; 28(10):4407-4420. Grieco SF, Holmes TC, Xu X. PMID: 36959497; PMCID: PMC10827671.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    28. Inferring neuron-neuron communications from single-cell transcriptomics through NeuronChat. Nat Commun. 2023 02 28; 14(1):1128. Zhao W, Johnston KG, Ren H, Xu X, Nie Q. PMID: 36854676; PMCID: PMC9974942.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    29. Stress-induced plasticity of a CRH/GABA projection disrupts reward behaviors in mice. Nat Commun. 2023 02 25; 14(1):1088. Birnie MT, Short AK, de Carvalho GB, Taniguchi L, Gunn BG, Pham AL, Itoga CA, Xu X, Chen LY, Mahler SV, Chen Y, Baram TZ. PMID: 36841826; PMCID: PMC9968307.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    30. Whole-brain input mapping of the lateral versus medial anterodorsal bed nucleus of the stria terminalis in the mouse. Neurobiol Stress. 2023 Mar; 23:100527. Sun Y, Zweifel LS, Holmes TC, Xu X. PMID: 36861029; PMCID: PMC9969273.
      View in: PubMed   Mentions: 2  
    31. Inferring neuron-neuron communications from single-cell transcriptomics through NeuronChat. bioRxiv. 2023 Jan 16. Zhao W, Johnston KG, Ren H, Xu X, Nie Q. PMID: 36712056; PMCID: PMC9882151.
      View in: PubMed   Mentions:
    32. Meeting report for the 2022 UC Irvine Center for neural circuit mapping conference: linking brain function to cell types and circuits. Mol Psychiatry. 2023 01; 28(1):2-3. Grieco SF, Holmes TC, Xu X. PMID: 36198768.
      View in: PubMed   Mentions: 1     Fields:    
    33. Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer's disease. Acta Neuropathol Commun. 2022 12 19; 10(1):182. Tan Z, Garduño BM, Aburto PF, Chen L, Ha N, Cogram P, Holmes TC, Xu X. PMID: 36529803; PMCID: PMC9761982.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    34. Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer's disease. Neurobiol Dis. 2023 01; 176:105939. Zhang H, Chen L, Johnston KG, Crapser J, Green KN, Ha NM, Tenner AJ, Holmes TC, Nitz DA, Xu X. PMID: 36462718; PMCID: PMC10187684.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    35. Development of highly sensitive, flexible dual L-glutamate and GABA microsensors for in vivo brain sensing. Biosens Bioelectron. 2023 Feb 15; 222:114941. Chu SS, Nguyen HA, Lin D, Bhatti M, Jones-Tinsley CE, Do AH, Frostig RD, Nenadic Z, Xu X, Lim MM, Cao H. PMID: 36455372.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    36. Psychedelics and Neural Plasticity: Therapeutic Implications. J Neurosci. 2022 11 09; 42(45):8439-8449. Grieco SF, Castrén E, Knudsen GM, Kwan AC, Olson DE, Zuo Y, Holmes TC, Xu X. PMID: 36351821; PMCID: PMC9665925.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    37. Hippocampal neural circuit connectivity alterations in an Alzheimer's disease mouse model revealed by monosynaptic rabies virus tracing. Neurobiol Dis. 2022 10 01; 172:105820. Ye Q, Gast G, Su X, Saito T, Saido TC, Holmes TC, Xu X. PMID: 35843448; PMCID: PMC9482455.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    38. Evidence of brain-derived neurotrophic factor in ameliorating cancer-related cognitive impairment: A systematic review of human studies. Crit Rev Oncol Hematol. 2022 Aug; 176:103748. Ng DQ, Chan D, Agrawal P, Zhao W, Xu X, Acharya M, Chan A. PMID: 35718064.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. Tracking longitudinal population dynamics of single neuronal calcium signal using SCOUT. Cell Rep Methods. 2022 05 23; 2(5):100207. Johnston KG, Grieco SF, Zhang H, Jin S, Xu X, Nie Q. PMID: 35637911; PMCID: PMC9142684.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    40. Longitudinal dynamics of microvascular recovery after acquired cortical injury. Acta Neuropathol Commun. 2022 04 25; 10(1):59. Lin X, Chen L, Jullienne A, Zhang H, Salehi A, Hamer M, C Holmes T, Obenaus A, Xu X. PMID: 35468870; PMCID: PMC9036719.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    41. Noncanonical projections to the hippocampal CA3 regulate spatial learning and memory by modulating the feedforward hippocampal trisynaptic pathway. PLoS Biol. 2021 12; 19(12):e3001127. Lin X, Amalraj M, Blanton C, Avila B, Holmes TC, Nitz DA, Xu X. PMID: 34928938; PMCID: PMC8741299.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    42. To deconvolve, or not to deconvolve: Inferences of neuronal activities using calcium imaging data. J Neurosci Methods. 2022 Jan 15; 366:109431. Shen T, Lur G, Xu X, Yu Z. PMID: 34856319; PMCID: PMC9482453.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    43. Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model. Neurobiol Dis. 2022 01; 162:105562. Lin X, Chen L, Baglietto-Vargas D, Kamalipour P, Ye Q, LaFerla FM, Nitz DA, Holmes TC, Xu X. PMID: 34838667; PMCID: PMC9482454.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    44. Beyond t test and ANOVA: applications of mixed-effects models for more rigorous statistical analysis in neuroscience research. Neuron. 2022 01 05; 110(1):21-35. Yu Z, Guindani M, Grieco SF, Chen L, Holmes TC, Xu X. PMID: 34784504; PMCID: PMC8763600.
      View in: PubMed   Mentions: 128     Fields:    
    45. Neuregulin signaling mediates the acute and sustained antidepressant effects of subanesthetic ketamine. Transl Psychiatry. 2021 02 24; 11(1):144. Grieco SF, Qiao X, Johnston KG, Chen L, Nelson RR, Lai C, Holmes TC, Xu X. PMID: 33627623; PMCID: PMC7904825.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    46. Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex. Nat Commun. 2021 02 08; 12(1):862. Zheng X, Salinas KJ, Velez DXF, Nakayama T, Lin X, Banerjee D, Xu X, Gandhi SP. PMID: 33558487; PMCID: PMC7870960.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    47. Microglia Elimination Increases Neural Circuit Connectivity and Activity in Adult Mouse Cortex. J Neurosci. 2021 02 10; 41(6):1274-1287. Liu YJ, Spangenberg EE, Tang B, Holmes TC, Green KN, Xu X. PMID: 33380470; PMCID: PMC7888230.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    48. Subanesthetic Ketamine Reactivates Adult Cortical Plasticity to Restore Vision from Amblyopia. Curr Biol. 2020 09 21; 30(18):3591-3603.e8. Grieco SF, Qiao X, Zheng X, Liu Y, Chen L, Zhang H, Yu Z, Gavornik JP, Lai C, Gandhi SP, Holmes TC, Xu X. PMID: 32822611; PMCID: PMC7925140.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    49. Viral Vectors for Neural Circuit Mapping and Recent Advances in Trans-synaptic Anterograde Tracers. Neuron. 2020 09 23; 107(6):1029-1047. Xu X, Holmes TC, Luo MH, Beier KT, Horwitz GD, Zhao F, Zeng W, Hui M, Semler BL, Sandri-Goldin RM. PMID: 32755550; PMCID: PMC7530073.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    50. Fos-CreER-based genetic mapping of forebrain regions activated by acupuncture. J Comp Neurol. 2020 04; 528(6):953-971. Guo Z, Lin X, Samaniego T, Isreb A, Cao S, Malik S, Holmes TC, Xu X. PMID: 31600836; PMCID: PMC7774513.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    51. Functional Reorganization of Local Circuit Connectivity in Superficial Spinal Dorsal Horn with Neuropathic Pain States. eNeuro. 2019 Sep/Oct; 6(5). Gong N, Hagopian G, Holmes TC, Luo ZD, Xu X. PMID: 31533959; PMCID: PMC6787342.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    52. CA1-projecting subiculum neurons facilitate object-place learning. Nat Neurosci. 2019 11; 22(11):1857-1870. Sun Y, Jin S, Lin X, Chen L, Qiao X, Jiang L, Zhou P, Johnston KG, Golshani P, Nie Q, Holmes TC, Nitz DA, Xu X. PMID: 31548723; PMCID: PMC6819262.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    53. Neuregulin and ErbB expression is regulated by development and sensory experience in mouse visual cortex. J Comp Neurol. 2020 02 15; 528(3):419-432. Grieco SF, Wang G, Mahapatra A, Lai C, Holmes TC, Xu X. PMID: 31454079; PMCID: PMC6901715.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    54. New viral-genetic mapping uncovers an enrichment of corticotropin-releasing hormone-expressing neuronal inputs to the nucleus accumbens from stress-related brain regions. J Comp Neurol. 2019 10 15; 527(15):2474-2487. Itoga CA, Chen Y, Fateri C, Echeverry PA, Lai JM, Delgado J, Badhon S, Short A, Baram TZ, Xu X. PMID: 30861133; PMCID: PMC6688927.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    55. Development of Local Circuit Connections to Hilar Mossy Cells in the Mouse Dentate Gyrus. eNeuro. 2019 Mar-Apr; 6(2). Shi Y, Grieco SF, Holmes TC, Xu X. PMID: 30937358; PMCID: PMC6439204.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    56. Geometry processing of conventionally produced mouse brain slice images. J Neurosci Methods. 2018 08 01; 306:45-56. Agarwal N, Xu X, Gopi M. PMID: 29689283; PMCID: PMC6086593.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    57. Neuregulin directed molecular mechanisms of visual cortical plasticity. J Comp Neurol. 2019 02 15; 527(3):668-678. Grieco SF, Holmes TC, Xu X. PMID: 29464684; PMCID: PMC6103898.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    58. c-Fos mapping of brain regions activated by multi-modal and electric foot shock stress. Neurobiol Stress. 2018 Feb; 8:92-102. Lin X, Itoga CA, Taha S, Li MH, Chen R, Sami K, Berton F, Francesconi W, Xu X. PMID: 29560385; PMCID: PMC5857493.
      View in: PubMed   Mentions: 25  
    59. Opposing and Complementary Topographic Connectivity Gradients Revealed by Quantitative Analysis of Canonical and Noncanonical Hippocampal CA1 Inputs. eNeuro. 2018 Jan-Feb; 5(1). Sun Y, Nitz DA, Holmes TC, Xu X. PMID: 29387780; PMCID: PMC5790753.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    60. Melanin concentrating hormone modulates oxytocin-mediated marble burying. Neuropharmacology. 2018 Jan; 128:22-32. Sanathara NM, Garau C, Alachkar A, Wang L, Wang Z, Nishimori K, Xu X, Civelli O. PMID: 28888943; PMCID: PMC5830107.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    61. Local and Long-Range Circuit Connections to Hilar Mossy Cells in the Dentate Gyrus. eNeuro. 2017 Mar-Apr; 4(2). Sun Y, Grieco SF, Holmes TC, Xu X. PMID: 28451637; PMCID: PMC5396130.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    62. Neuregulin-1/ErbB4 Signaling Regulates Visual Cortical Plasticity. Neuron. 2016 Oct 05; 92(1):160-173. Sun Y, Ikrar T, Davis MF, Gong N, Zheng X, Luo ZD, Lai C, Mei L, Holmes TC, Gandhi SP, Xu X. PMID: 27641496; PMCID: PMC5310354.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    63. Differential arousal regulation by prokineticin 2 signaling in the nocturnal mouse and the diurnal monkey. Mol Brain. 2016 08 18; 9(1):78. Zhou QY, Burton KJ, Neal ML, Qiao Y, Kanthasamy AG, Sun Y, Xu X, Ma Y, Li X. PMID: 27535380; PMCID: PMC4989352.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    64. Noncanonical connections between the subiculum and hippocampal CA1. J Comp Neurol. 2016 12 01; 524(17):3666-3673. Xu X, Sun Y, Holmes TC, López AJ. PMID: 27150503; PMCID: PMC5050062.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    65. High-resolution and cell-type-specific photostimulation mapping shows weak excitatory vs. strong inhibitory inputs in the bed nucleus of the stria terminalis. J Neurophysiol. 2016 06 01; 115(6):3204-16. Xu X, Ikrar T, Sun Y, Santos R, Holmes TC, Francesconi W, Berton F. PMID: 27052587; PMCID: PMC4946595.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    66. Genetic cell targeting uncovers specific neuronal types and distinct subregions in the bed nucleus of the stria terminalis. J Comp Neurol. 2016 08 15; 524(12):2379-99. Nguyen AQ, Dela Cruz JA, Sun Y, Holmes TC, Xu X. PMID: 26718312; PMCID: PMC5359980.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    67. Large-scale neural circuit mapping data analysis accelerated with the graphical processing unit (GPU). J Neurosci Methods. 2015 Jan 15; 239:1-10. Shi Y, Veidenbaum AV, Nicolau A, Xu X. PMID: 25277633; PMCID: PMC4268008.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    68. Bidirectional global spontaneous network activity precedes the canonical unidirectional circuit organization in the developing hippocampus. J Comp Neurol. 2014 Jun 15; 522(9):2191-208. Shi Y, Ikrar T, Olivas ND, Xu X. PMID: 24357090; PMCID: PMC4293468.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    69. Distinct physiological and developmental properties of hippocampal CA2 subfield revealed by using anti-Purkinje cell protein 4 (PCP4) immunostaining. J Comp Neurol. 2014 Apr 15; 522(6):1333-54. San Antonio A, Liban K, Ikrar T, Tsyganovskiy E, Xu X. PMID: 24166578; PMCID: PMC4001794.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    70. Cell-type-specific circuit connectivity of hippocampal CA1 revealed through Cre-dependent rabies tracing. Cell Rep. 2014 Apr 10; 7(1):269-80. Sun Y, Nguyen AQ, Nguyen JP, Le L, Saur D, Choi J, Callaway EM, Xu X. PMID: 24656815; PMCID: PMC3998524.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    71. Histamine inhibits the melanin-concentrating hormone system: implications for sleep and arousal. J Physiol. 2014 May 15; 592(10):2183-96. Parks GS, Olivas ND, Ikrar T, Sanathara NM, Wang L, Wang Z, Civelli O, Xu X. PMID: 24639485; PMCID: PMC4227902.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    72. Adult neurogenesis modifies excitability of the dentate gyrus. Front Neural Circuits. 2013; 7:204. Ikrar T, Guo N, He K, Besnard A, Levinson S, Hill A, Lee HK, Hen R, Xu X, Sahay A. PMID: 24421758; PMCID: PMC3872742.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    73. Optical stimulation and imaging of functional brain circuitry in a segmented laminar flow chamber. Lab Chip. 2013 Feb 21; 13(4):536-41. Ahrar S, Nguyen TV, Shi Y, Ikrar T, Xu X, Hui EE. PMID: 23044655; PMCID: PMC3554874.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    74. Cell-type specific inactivation of hippocampal CA1 disrupts location-dependent object recognition in the mouse. Learn Mem. 2013 Feb 15; 20(3):139-46. Haettig J, Sun Y, Wood MA, Xu X. PMID: 23418393; PMCID: PMC3578275.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    75. Laminar circuit organization and response modulation in mouse visual cortex. Front Neural Circuits. 2012; 6:70. Olivas ND, Quintanar-Zilinskas V, Nenadic Z, Xu X. PMID: 23060751; PMCID: PMC3464489.
      View in: PubMed   Mentions: 10     Fields:    
    76. Cell-type specific regulation of cortical excitability through the allatostatin receptor system. Front Neural Circuits. 2012; 6:2. Ikrar T, Shi Y, Velasquez T, Goulding M, Xu X. PMID: 22319474; PMCID: PMC3262160.
      View in: PubMed   Mentions: 8     Fields:    
    77. Mapping inhibitory neuronal circuits by laser scanning photostimulation. J Vis Exp. 2011 Oct 06; (56). Ikrar T, Olivas ND, Shi Y, Xu X. PMID: 22006064; PMCID: PMC3227169.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    78. Oligodendrocytes as regulators of neuronal networks during early postnatal development. PLoS One. 2011 May 12; 6(5):e19849. Doretto S, Malerba M, Ramos M, Ikrar T, Kinoshita C, De Mei C, Tirotta E, Xu X, Borrelli E. PMID: 21589880; PMCID: PMC3093406.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    79. Novel use of matched filtering for synaptic event detection and extraction. PLoS One. 2010 Nov 24; 5(11):e15517. Shi Y, Nenadic Z, Xu X. PMID: 21124805; PMCID: PMC2991367.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    80. High precision and fast functional mapping of cortical circuitry through a novel combination of voltage sensitive dye imaging and laser scanning photostimulation. J Neurophysiol. 2010 Apr; 103(4):2301-12. Xu X, Olivas ND, Levi R, Ikrar T, Nenadic Z. PMID: 20130040; PMCID: PMC2853294.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
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