Brian John Cummings

Title(s)Professor, Physical Medicine and Rehabilitation
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-3254
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    Collapse Research 
    Collapse Research Activities and Funding
    Multi-channeled Bridges for Promoting Chronic Spinal Cord Repair
    NIH R01NS117103Sep 1, 2020 - Jul 31, 2025
    Role: Co-Principal Investigator
    Human neural stem cell therapy for the treatment of cervical spinal cord injury (
    NIH U01NS079420Sep 1, 2013 - Aug 31, 2016
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury. Brain Behav Immun. 2024 Nov 27. Karam J, Ashfaq N, Benitez C, Morales V, Partida E, Hernandez M, Yokoyama J, Villegas A, Brown B, Sakthivel P, Anderson AJ, Cummings BJ. PMID: 39612965.
      View in: PubMed   Mentions:    Fields:    
    2. Injured inflammatory environment overrides the TET2 shaped epigenetic landscape of pluripotent stem cell derived human neural stem cells. Sci Rep. 2024 10 24; 14(1):25186. Kamei N, Day K, Guo W, Haus DL, Nguyen HX, Scarfone VM, Booher K, Jia XY, Cummings BJ, Anderson AJ. PMID: 39448736; PMCID: PMC11502794.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI. NPJ Regen Med. 2024 Mar 18; 9(1):12. Nekanti U, Sakthivel PS, Zahedi A, Creasman DA, Nishi RA, Dumont CM, Piltti KM, Guardamondo GL, Hernandez N, Chen X, Song H, Lin X, Martinez J, On L, Lakatos A, Pawar K, David BT, Guo Z, Seidlits SK, Xu X, Shea LD, Cummings BJ, Anderson AJ. PMID: 38499577; PMCID: PMC10948859.
      View in: PubMed   Mentions:
    4. Neuroinflammation drives sex-dependent effects on pain and negative affect in a murine model of repeated mild traumatic brain injury. Pain. 2024 Apr 01; 165(4):848-865. Liu SS, Pickens S, Barta Z, Rice M, Dagher M, Lebens R, Nguyen TV, Cummings BJ, Cahill CM. PMID: 37943063; PMCID: PMC10949215.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    5. Building-Block Size Mediates Microporous Annealed Particle Hydrogel Tube Microenvironment Following Spinal Cord Injury. Adv Healthc Mater. 2024 Oct; 13(25):e2302498. Ross BC, Kent RN, Saunders MN, Schwartz SR, Smiley BM, Hocevar SE, Chen SC, Xiao C, Williams LA, Anderson AJ, Cummings BJ, Baker BM, Shea LD. PMID: 37768019; PMCID: PMC10972780.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    6. Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI. Res Sq. 2023 Jul 19. Nekanti U, Sakthivel P, Zahedi A, Creasman DA, Nishi RA, Dumont CM, Piltti KM, Guardamondo GL, Hernandez N, Chen X, Song H, Lin X, Martinez J, On L, Lakatos A, Pawar K, David BT, Guo Z, Seidlits SK, Xu X, Shea LD, Cummings BJ, Anderson AJ. PMID: 37502943; PMCID: PMC10371146.
      View in: PubMed   Mentions:
    7. Biodegradable nanoparticles targeting circulating immune cells reduce central and peripheral sensitization to alleviate neuropathic pain following spinal cord injury. Pain. 2024 Jan 01; 165(1):92-101. Saunders MN, Griffin KV, Kalashnikova I, Kolpek D, Smith DR, Saito E, Cummings BJ, Anderson AJ, Shea LD, Park J. PMID: 37463227; PMCID: PMC10787809.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    8. The endogenous progenitor response following traumatic brain injury: a target for cell therapy paradigms. Neural Regen Res. 2022 Nov; 17(11):2351-2354. Badner A, Cummings BJ. PMID: 35535870; PMCID: PMC9120693.
      View in: PubMed   Mentions: 4  
    9. Online seminars as an information source for direct-to-consumer stem cell therapy. Regen Med. 2022 02; 17(2):81-90. Hassoun M, Golub S, Greenfield S, Grill JD, Cummings BJ. PMID: 34949108; PMCID: PMC10694786.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    10. Freshly Thawed Cryobanked Human Neural Stem Cells Engraft within Endogenous Neurogenic Niches and Restore Cognitive Function after Chronic Traumatic Brain Injury. J Neurotrauma. 2021 10 01; 38(19):2731-2746. Badner A, Reinhardt EK, Nguyen TV, Midani N, Marshall AT, Lepe CA, Echeverria K, Lepe JJ, Torrecampo V, Bertan SH, Tran SH, Anderson AJ, Cummings BJ. PMID: 34130484.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    11. Complement C6 deficiency exacerbates pathophysiology after spinal cord injury. Sci Rep. 2020 11 11; 10(1):19500. Su D, Hooshmand MJ, Galvan MD, Nishi RA, Cummings BJ, Anderson AJ. PMID: 33177623; PMCID: PMC7659012.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    12. Polycistronic Delivery of IL-10 and NT-3 Promotes Oligodendrocyte Myelination and Functional Recovery in a Mouse Spinal Cord Injury Model. Tissue Eng Part A. 2020 06; 26(11-12):672-682. Smith DR, Dumont CM, Park J, Ciciriello AJ, Guo A, Tatineni R, Cummings BJ, Anderson AJ, Shea LD. PMID: 32000627; PMCID: PMC7310216.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    13. PLG Bridge Implantation in Chronic SCI Promotes Axonal Elongation and Myelination. ACS Biomater Sci Eng. 2019 Dec 09; 5(12):6679-6690. Smith DR, Dumont CM, Ciciriello AJ, Guo A, Tatineni R, Munsell MK, Cummings BJ, Anderson AJ, Shea LD. PMID: 33423486; PMCID: PMC11283858.
      View in: PubMed   Mentions: 4     Fields:    
    14. Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. Neuron. 2019 09 25; 103(6):1016-1033.e10. Hasselmann J, Coburn MA, England W, Figueroa Velez DX, Kiani Shabestari S, Tu CH, McQuade A, Kolahdouzan M, Echeverria K, Claes C, Nakayama T, Azevedo R, Coufal NG, Han CZ, Cummings BJ, Davtyan H, Glass CK, Healy LM, Gandhi SP, Spitale RC, Blurton-Jones M. PMID: 31375314; PMCID: PMC7138101.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansAnimalsCells
    15. Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury. Proc Natl Acad Sci U S A. 2019 07 23; 116(30):14947-14954. Park J, Zhang Y, Saito E, Gurczynski SJ, Moore BB, Cummings BJ, Anderson AJ, Shea LD. PMID: 31285339; PMCID: PMC6660718.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    16. Aligned hydrogel tubes guide regeneration following spinal cord injury. Acta Biomater. 2019 03 01; 86:312-322. Dumont CM, Carlson MA, Munsell MK, Ciciriello AJ, Strnadova K, Park J, Cummings BJ, Anderson AJ, Shea LD. PMID: 30610918; PMCID: PMC6369008.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    17. Combinatorial lentiviral gene delivery of pro-oligodendrogenic factors for improving myelination of regenerating axons after spinal cord injury. Biotechnol Bioeng. 2019 01; 116(1):155-167. Smith DR, Margul DJ, Dumont CM, Carlson MA, Munsell MK, Johnson M, Cummings BJ, Anderson AJ, Shea LD. PMID: 30229864; PMCID: PMC6289889.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    18. Spinal Progenitor-Laden Bridges Support Earlier Axon Regeneration Following Spinal Cord Injury. Tissue Eng Part A. 2018 11; 24(21-22):1588-1602. Dumont CM, Munsell MK, Carlson MA, Cummings BJ, Anderson AJ, Shea LD. PMID: 30215293; PMCID: PMC6238608.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    19. Reducing inflammation through delivery of lentivirus encoding for anti-inflammatory cytokines attenuates neuropathic pain after spinal cord injury. J Control Release. 2018 11 28; 290:88-101. Park J, Decker JT, Smith DR, Cummings BJ, Anderson AJ, Shea LD. PMID: 30296461; PMCID: PMC6240362.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    20. Feasibility study on mouse live imaging after spinal cord injury and poly(lactide-co-glycolide) bridge implantation. J Biomed Opt. 2018 06; 23(6):1-6. Anzalone A, Chacko JV, Nishi RA, Dumont C, Smith D, Shea LD, Digman MA, Cummings BJ, Anderson AJ. PMID: 29959835; PMCID: PMC8357334.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    21. Local Immunomodulation with Anti-inflammatory Cytokine-Encoding Lentivirus Enhances Functional Recovery after Spinal Cord Injury. Mol Ther. 2018 07 05; 26(7):1756-1770. Park J, Decker JT, Margul DJ, Smith DR, Cummings BJ, Anderson AJ, Shea LD. PMID: 29778523; PMCID: PMC6037204.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    22. Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral Deficits. ASN Neuro. 2018 Jan-Dec; 10:1759091418781921. Gold EM, Vasilevko V, Hasselmann J, Tiefenthaler C, Hoa D, Ranawaka K, Cribbs DH, Cummings BJ. PMID: 29932344; PMCID: PMC6050992.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    23. Live-cell time-lapse imaging and single-cell tracking of in vitro cultured neural stem cells - Tools for analyzing dynamics of cell cycle, migration, and lineage selection. Methods. 2018 01 15; 133:81-90. Piltti KM, Cummings BJ, Carta K, Manughian-Peter A, Worne CL, Singh K, Ong D, Maksymyuk Y, Khine M, Anderson AJ. PMID: 29050826; PMCID: PMC6166405.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    24. Neutrophils Induce Astroglial Differentiation and Migration of Human Neural Stem Cells via C1q and C3a Synthesis. J Immunol. 2017 08 01; 199(3):1069-1085. Hooshmand MJ, Nguyen HX, Piltti KM, Benavente F, Hong S, Flanagan L, Uchida N, Cummings BJ, Anderson AJ. PMID: 28687659; PMCID: PMC5523578.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    25. Effects of Human ES-Derived Neural Stem Cell Transplantation and Kindling in a Rat Model of Traumatic Brain Injury. Cell Transplant. 2017 07; 26(7):1247-1261. Beretta S, Cunningham KM, Haus DL, Gold EM, Perez H, López-Velázquez L, Cummings BJ. PMID: 28933218; PMCID: PMC5657732.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    26. Increasing Human Neural Stem Cell Transplantation Dose Alters Oligodendroglial and Neuronal Differentiation after Spinal Cord Injury. Stem Cell Reports. 2017 06 06; 8(6):1534-1548. Piltti KM, Funes GM, Avakian SN, Salibian AA, Huang KI, Carta K, Kamei N, Flanagan LA, Monuki ES, Uchida N, Cummings BJ, Anderson AJ. PMID: 28479305; PMCID: PMC5469937.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    27. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 2017 Apr 19; 94(2):278-293.e9. Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, Gylys KH, Cahalan MD, Cummings BJ, Antel JP, Mortazavi A, Carson MJ, Poon WW, Blurton-Jones M. PMID: 28426964; PMCID: PMC5482419.
      View in: PubMed   Mentions: 483     Fields:    Translation:HumansAnimalsCells
    28. Response to StemCells Inc. Stem Cell Reports. 2017 02 14; 8(2):195-197. Monuki ES, Anderson AJ, Blurton-Jones M, Cummings BJ. PMID: 28199827; PMCID: PMC5312268.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. Preclinical Efficacy Failure of Human CNS-Derived Stem Cells for Use in the Pathway Study of Cervical Spinal Cord Injury. Stem Cell Reports. 2017 02 14; 8(2):249-263. Anderson AJ, Piltti KM, Hooshmand MJ, Nishi RA, Cummings BJ. PMID: 28199829; PMCID: PMC5312249.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    30. Effects of concussion on the blood-brain barrier in humans and rodents. J Concussion. 2017 Jan-Dec; 1. Sahyouni R, Gutierrez P, Gold E, Robertson RT, Cummings BJ. PMID: 30828466; PMCID: PMC6391889.
      View in: PubMed   Mentions: 12  
    31. Achieving Informed Consent for Cellular Therapies: A Preclinical Translational Research Perspective on Regulations versus a Dose of Reality. J Law Med Ethics. 2016 09; 44(3):394-401. Anderson AJ, Cummings BJ. PMID: 27587445; PMCID: PMC5435227.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    32. Transplantation of human neural stem cells restores cognition in an immunodeficient rodent model of traumatic brain injury. Exp Neurol. 2016 07; 281:1-16. Haus DL, López-Velázquez L, Gold EM, Cunningham KM, Perez H, Anderson AJ, Cummings BJ. PMID: 27079998.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    33. Stem cell therapies for traumatic brain injury. Regen Med. 2015 Nov; 10(8):917-20. Koliatsos VE, Xu L, Cummings BJ. PMID: 26542417.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    34. A meta-analysis of efficacy in pre-clinical human stem cell therapies for traumatic brain injury. Exp Neurol. 2015 Nov; 273:225-33. Chang J, Phelan M, Cummings BJ. PMID: 26342754.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    35. Transplantation dose alters the dynamics of human neural stem cell engraftment, proliferation and migration after spinal cord injury. Stem Cell Res. 2015 Sep; 15(2):341-53. Piltti KM, Avakian SN, Funes GM, Hu A, Uchida N, Anderson AJ, Cummings BJ. PMID: 26298025; PMCID: PMC4600655.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    36. Biomaterial bridges enable regeneration and re-entry of corticospinal tract axons into the caudal spinal cord after SCI: Association with recovery of forelimb function. Biomaterials. 2015 Oct; 65:1-12. Pawar K, Cummings BJ, Thomas A, Shea LD, Levine A, Pfaff S, Anderson AJ. PMID: 26134079; PMCID: PMC4523232.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    37. Transplantation of human oligodendrocyte progenitor cells in an animal model of diffuse traumatic axonal injury: survival and differentiation. Stem Cell Res Ther. 2015 May 14; 6:93. Xu L, Ryu J, Hiel H, Menon A, Aggarwal A, Rha E, Mahairaki V, Cummings BJ, Koliatsos VE. PMID: 25971252; PMCID: PMC4453242.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    38. CD133-enriched Xeno-Free human embryonic-derived neural stem cells expand rapidly in culture and do not form teratomas in immunodeficient mice. Stem Cell Res. 2014 Sep; 13(2):214-26. Haus DL, Nguyen HX, Gold EM, Kamei N, Perez H, Moore HD, Anderson AJ, Cummings BJ. PMID: 25082219; PMCID: PMC5675021.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    39. Sonic hedgehog and neurotrophin-3 increase oligodendrocyte numbers and myelination after spinal cord injury. Integr Biol (Camb). 2014 Jul 24; 6(7):694-705. Thomas AM, Seidlits SK, Goodman AG, Kukushliev TV, Hassani DM, Cummings BJ, Anderson AJ, Shea LD. PMID: 24873988; PMCID: PMC4086750.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    40. Induction of early neural precursors and derivation of tripotent neural stem cells from human pluripotent stem cells under xeno-free conditions. J Comp Neurol. 2014 Aug 15; 522(12):2767-83. Nguyen HX, Nekanti U, Haus DL, Funes G, Moreno D, Kamei N, Cummings BJ, Anderson AJ. PMID: 24715528.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    41. Injury to the spinal cord niche alters the engraftment dynamics of human neural stem cells. Stem Cell Reports. 2014 May 06; 2(5):620-32. Sontag CJ, Uchida N, Cummings BJ, Anderson AJ. PMID: 24936450; PMCID: PMC4050489.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    42. Long-term characterization of axon regeneration and matrix changes using multiple channel bridges for spinal cord regeneration. Tissue Eng Part A. 2014 Mar; 20(5-6):1027-37. Tuinstra HM, Margul DJ, Goodman AG, Boehler RM, Holland SJ, Zelivyanskaya ML, Cummings BJ, Anderson AJ, Shea LD. PMID: 24168314; PMCID: PMC3938917.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    43. Safety of human neural stem cell transplantation in chronic spinal cord injury. Stem Cells Transl Med. 2013 Dec; 2(12):961-74. Piltti KM, Salazar DL, Uchida N, Cummings BJ, Anderson AJ. PMID: 24191264; PMCID: PMC3841091.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    44. Immunosuppressants affect human neural stem cells in vitro but not in an in vivo model of spinal cord injury. Stem Cells Transl Med. 2013 Oct; 2(10):731-44. Sontag CJ, Nguyen HX, Kamei N, Uchida N, Anderson AJ, Cummings BJ. PMID: 23981724; PMCID: PMC3785258.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    45. Functional assessment of long-term deficits in rodent models of traumatic brain injury. Regen Med. 2013 Jul; 8(4):483-516. Gold EM, Su D, López-Velázquez L, Haus DL, Perez H, Lacuesta GA, Anderson AJ, Cummings BJ. PMID: 23826701.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    46. Safety of epicenter versus intact parenchyma as a transplantation site for human neural stem cells for spinal cord injury therapy. Stem Cells Transl Med. 2013 Mar; 2(3):204-16. Piltti KM, Salazar DL, Uchida N, Cummings BJ, Anderson AJ. PMID: 23413374; PMCID: PMC3659765.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    47. Channel density and porosity of degradable bridging scaffolds on axon growth after spinal injury. Biomaterials. 2013 Mar; 34(9):2213-20. Thomas AM, Kubilius MB, Holland SJ, Seidlits SK, Boehler RM, Anderson AJ, Cummings BJ, Shea LD. PMID: 23290832; PMCID: PMC3552139.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    48. Human neural stem cells induce functional myelination in mice with severe dysmyelination. Sci Transl Med. 2012 Oct 10; 4(155):155ra136. Uchida N, Chen K, Dohse M, Hansen KD, Dean J, Buser JR, Riddle A, Beardsley DJ, Wan Y, Gong X, Nguyen T, Cummings BJ, Anderson AJ, Tamaki SJ, Tsukamoto A, Weissman IL, Matsumoto SG, Sherman LS, Kroenke CD, Back SA. PMID: 23052293; PMCID: PMC3864816.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimalsCells
    49. Detection of Mutant Huntingtin Aggregation Conformers and Modulation of SDS-Soluble Fibrillar Oligomers by Small Molecules. J Huntingtons Dis. 2012; 1(1):119-32. Sontag EM, Lotz GP, Yang G, Sontag CJ, Cummings BJ, Glabe CG, Muchowski PJ, Thompson LM. PMID: 24086178; PMCID: PMC3786168.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    50. Multifunctional, multichannel bridges that deliver neurotrophin encoding lentivirus for regeneration following spinal cord injury. Biomaterials. 2012 Feb; 33(5):1618-26. Tuinstra HM, Aviles MO, Shin S, Holland SJ, Zelivyanskaya ML, Fast AG, Ko SY, Margul DJ, Bartels AK, Boehler RM, Cummings BJ, Anderson AJ, Shea LD. PMID: 22130565; PMCID: PMC3237872.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    51. Computer-aided 2D and 3D quantification of human stem cell fate from in vitro samples using Volocity high performance image analysis software. Stem Cell Res. 2011 Nov; 7(3):256-63. Piltti KM, Haus DL, Do E, Perez H, Anderson AJ, Cummings BJ. PMID: 21775237.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    52. Achieving stable human stem cell engraftment and survival in the CNS: is the future of regenerative medicine immunodeficient? Regen Med. 2011 May; 6(3):367-406. Anderson AJ, Haus DL, Hooshmand MJ, Perez H, Sontag CJ, Cummings BJ. PMID: 21548741; PMCID: PMC3403688.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    53. Human neural stem cells differentiate and promote locomotor recovery in an early chronic spinal cord injury NOD-scid mouse model. PLoS One. 2010 Aug 18; 5(8):e12272. Salazar DL, Uchida N, Hamers FP, Cummings BJ, Anderson AJ. PMID: 20806064; PMCID: PMC2923623.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansAnimalsCells
    54. Comparison of immunopathology and locomotor recovery in C57BL/6, BUB/BnJ, and NOD-SCID mice after contusion spinal cord injury. J Neurotrauma. 2010 Feb; 27(2):411-21. Luchetti S, Beck KD, Galvan MD, Silva R, Cummings BJ, Anderson AJ. PMID: 19831737; PMCID: PMC2834443.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    55. Multiple channel bridges for spinal cord injury: cellular characterization of host response. Tissue Eng Part A. 2009 Nov; 15(11):3283-95. Yang Y, De Laporte L, Zelivyanskaya ML, Whittlesey KJ, Anderson AJ, Cummings BJ, Shea LD. PMID: 19382871; PMCID: PMC2792065.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    56. Long-term, stable differentiation of human embryonic stem cell-derived neural precursors grafted into the adult mammalian neostriatum. Stem Cells. 2009 Oct; 27(10):2414-26. Nasonkin I, Mahairaki V, Xu L, Hatfield G, Cummings BJ, Eberhart C, Ryugo DK, Maric D, Bar E, Koliatsos VE. PMID: 19609935; PMCID: PMC2906132.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    57. Analysis of host-mediated repair mechanisms after human CNS-stem cell transplantation for spinal cord injury: correlation of engraftment with recovery. PLoS One. 2009 Jun 11; 4(6):e5871. Hooshmand MJ, Sontag CJ, Uchida N, Tamaki S, Anderson AJ, Cummings BJ. PMID: 19517014; PMCID: PMC2690693.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    58. Plasmid releasing multiple channel bridges for transgene expression after spinal cord injury. Mol Ther. 2009 Feb; 17(2):318-26. De Laporte L, Yang Y, Zelivyanskaya ML, Cummings BJ, Anderson AJ, Shea LD. PMID: 19050701; PMCID: PMC2835056.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    59. Adaptation of a ladder beam walking task to assess locomotor recovery in mice following spinal cord injury. Behav Brain Res. 2007 Feb 27; 177(2):232-41. Cummings BJ, Engesser-Cesar C, Cadena G, Anderson AJ. PMID: 17197044; PMCID: PMC1892162.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    60. Human neural stem cell differentiation following transplantation into spinal cord injured mice: association with recovery of locomotor function. Neurol Res. 2006 Jul; 28(5):474-81. Cummings BJ, Uchida N, Tamaki SJ, Anderson AJ. PMID: 16808875.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    61. Comparative non-radioactive RT-PCR assay: an approach to study the neurosteroids biosynthetic pathway in humans. J Neurosci Methods. 2006 Jun 15; 153(2):290-8. Luchetti S, di Michele F, Romeo E, Brusa L, Bernardi G, Cummings BJ, Longone P. PMID: 16378642.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    62. BioVision: an application for the automated image analysis of histological sections. Neurobiol Aging. 2006 Oct; 27(10):1462-76. Chubb C, Inagaki Y, Sheu P, Cummings B, Wasserman A, Head E, Cotman C. PMID: 16271803.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    63. Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):14069-74. Cummings BJ, Uchida N, Tamaki SJ, Salazar DL, Hooshmand M, Summers R, Gage FH, Anderson AJ. PMID: 16172374; PMCID: PMC1216836.
      View in: PubMed   Mentions: 297     Fields:    Translation:HumansAnimalsCells
    64. Alzheimer's disease--a sum greater than its parts? Neurobiol Aging. 2004 Jul; 25(6):725-33; discussion 743-6. Adlard PA, Cummings BJ. PMID: 15165695.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    65. The induction of the TNFalpha death domain signaling pathway in Alzheimer's disease brain. Neurochem Res. 2003 Feb; 28(2):307-18. Zhao M, Cribbs DH, Anderson AJ, Cummings BJ, Su JH, Wasserman AJ, Cotman CW. PMID: 12608703.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    66. Optimization of techniques for the maximal detection and quantification of Alzheimer's-related neuropathology with digital imaging. Neurobiol Aging. 2002 Mar-Apr; 23(2):161-70. Cummings BJ, Mason AJ, Kim RC, Sheu PC, Anderson AJ. PMID: 11804699.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    67. DNA damage and apoptosis in the aged canine brain: relationship to Abeta deposition in the absence of neuritic pathology. Prog Neuropsychopharmacol Biol Psychiatry. 2000 Jul; 24(5):787-99. Anderson AJ, Ruehl WW, Fleischmann LK, Stenstrom K, Entriken TL, Cummings BJ. PMID: 11191713.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    68. Plaque biogenesis in brain aging and Alzheimer's disease. II. Progressive transformation and developmental sequence of dystrophic neurites. Acta Neuropathol. 1998 Nov; 96(5):463-71. Su JH, Cummings BJ, Cotman CW. PMID: 9829809.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    69. Therapeutic actions of L-deprenyl in dogs: a model of human brain aging. Adv Pharmacol. 1998; 42:316-9. Ruehl WW, Neilson J, Hart B, Head E, Bruyette DS, Cummings BJ. PMID: 9327904.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    70. The progression of beta-amyloid deposition in the frontal cortex of the aged canine. Brain Res. 1997 Nov 07; 774(1-2):35-43. Satou T, Cummings BJ, Head E, Nielson KA, Hahn FF, Milgram NW, Velazquez P, Cribbs DH, Tenner AJ, Cotman CW. PMID: 9452189.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    71. Open field activity and human interaction as a function of age and breed in dogs. Physiol Behav. 1997 Nov; 62(5):963-71. Head E, Callahan H, Cummings BJ, Cotman CW, Ruehl WW, Muggenberg BA, Milgram NW. PMID: 9333188.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    72. Plaques and tangles: searching for primary events in a forest of data. Neurobiol Aging. 1997 Jul-Aug; 18(4):358-62; discussion 389-92. Cummings BJ. PMID: 9330962.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    73. Constructional apraxia in Alzheimer's disease correlates with neuritic neuropathology in occipital cortex. Brain Res. 1996 Nov 25; 741(1-2):284-93. Nielson KA, Cummings BJ, Cotman CW. PMID: 9001734.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    74. Plaque biogenesis in brain aging and Alzheimer's disease. I. Progressive changes in phosphorylation states of paired helical filaments and neurofilaments. Brain Res. 1996 Nov 11; 739(1-2):79-87. Su JH, Cummings BJ, Cotman CW. PMID: 8955927.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    75. Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease. Neurobiol Aging. 1996 Nov-Dec; 17(6):921-33. Cummings BJ, Pike CJ, Shankle R, Cotman CW. PMID: 9363804.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    76. beta-Amyloid converts an acute phase injury response to chronic injury responses. Neurobiol Aging. 1996 Sep-Oct; 17(5):723-31. Cotman CW, Tenner AJ, Cummings BJ. PMID: 8892345.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    77. Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine. Neurobiol Learn Mem. 1996 Jul; 66(1):11-23. Cummings BJ, Head E, Afagh AJ, Milgram NW, Cotman CW. PMID: 8661247.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    78. Diffuse plaques contain C-terminal A beta 42 and not A beta 40: evidence from cats and dogs. Neurobiol Aging. 1996 Jul-Aug; 17(4):653-9. Cummings BJ, Satou T, Head E, Milgram NW, Cole GM, Savage MJ, Podlisny MB, Selkoe DJ, Siman R, Greenberg BD, Cotman CW. PMID: 8832640.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    79. Localization and cell association of C1q in Alzheimer's disease brain. Exp Neurol. 1996 Mar; 138(1):22-32. Afagh A, Cummings BJ, Cribbs DH, Cotman CW, Tenner AJ. PMID: 8593893.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    80. The canine as an animal model of human aging and dementia. Neurobiol Aging. 1996 Mar-Apr; 17(2):259-68. Cummings BJ, Head E, Ruehl W, Milgram NW, Cotman CW. PMID: 8744407.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimals
    81. Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity. Lancet. 1995 Dec 09; 346(8989):1524-8. Cummings BJ, Cotman CW. PMID: 7491048.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    82. Immunoreactivity for Bcl-2 protein within neurons in the Alzheimer's disease brain increases with disease severity. Brain Res. 1995 Oct 30; 697(1-2):35-43. Satou T, Cummings BJ, Cotman CW. PMID: 8593592.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    83. Spatial learning and memory as a function of age in the dog. Behav Neurosci. 1995 Oct; 109(5):851-8. Head E, Mehta R, Hartley J, Kameka M, Cummings BJ, Cotman CW, Ruehl WW, Milgram NW. PMID: 8554710.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    84. Early association of reactive astrocytes with senile plaques in Alzheimer's disease. Exp Neurol. 1995 Apr; 132(2):172-9. Pike CJ, Cummings BJ, Cotman CW. PMID: 7789457.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    85. Color image analysis in neuroanatomical research: application to senile plaque subtype quantification in Alzheimer's disease. Neurobiol Aging. 1995 Mar-Apr; 16(2):211-23. Defigueiredo RJ, Cummings BJ, Mundkur PY, Cotman CW. PMID: 7777139.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    86. Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: clinical presentation, cognitive testing, pathology and response to 1-deprenyl therapy. Prog Brain Res. 1995; 106:217-25. Ruehl WW, Bruyette DS, DePaoli A, Cotman CW, Head E, Milgram NW, Cummings BJ. PMID: 8584657.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    87. Immunohistochemical evidence for apoptosis in Alzheimer's disease. Neuroreport. 1994 Dec 20; 5(18):2529-33. Su JH, Anderson AJ, Cummings BJ, Cotman CW. PMID: 7696596.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansCells
    88. Early phosphorylation of tau in Alzheimer's disease occurs at Ser-202 and is preferentially located within neurites. Neuroreport. 1994 Nov 21; 5(17):2358-62. Su JH, Cummings BJ, Cotman CW. PMID: 7533559.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    89. Beta-amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease. Neuroscience. 1994 Nov; 63(2):517-31. Pike CJ, Cummings BJ, Monzavi R, Cotman CW. PMID: 7891862.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    90. Analysis of brain injury following intrahippocampal administration of beta-amyloid in streptozotocin-treated rats. Neurobiol Aging. 1994 Mar-Apr; 15(2):153-9. Smyth MD, Kesslak JP, Cummings BJ, Cotman CW. PMID: 7838285.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    91. Subpopulations of dystrophic neurites [correction of neuritis] in Alzheimer's brain with distinct immunocytochemical and argentophilic characteristics. Brain Res. 1994 Feb 21; 637(1-2):37-44. Su JH, Cummings BJ, Cotman CW. PMID: 8180819.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    92. Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer's disease: association with pathology. Exp Neurol. 1994 Feb; 125(2):286-95. Anderson AJ, Cummings BJ, Cotman CW. PMID: 8313943.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    93. Neuritic involvement within bFGF immunopositive plaques of Alzheimer's disease. Exp Neurol. 1993 Dec; 124(2):315-25. Cummings BJ, Su JH, Cotman CW. PMID: 8287930.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    94. Beta-amyloid accumulation in aged canine brain: a model of early plaque formation in Alzheimer's disease. Neurobiol Aging. 1993 Nov-Dec; 14(6):547-60. Cummings BJ, Su JH, Cotman CW, White R, Russell MJ. PMID: 8295657.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    95. Identification and distribution of axonal dystrophic neurites in Alzheimer's disease. Brain Res. 1993 Oct 22; 625(2):228-37. Su JH, Cummings BJ, Cotman CW. PMID: 8275305.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    96. Life span changes in the verbal categorization of odors. J Gerontol. 1993 Mar; 48(2):P49-53. Russell MJ, Cummings BJ, Profitt BF, Wysocki CJ, Gilbert AN, Cotman CW. PMID: 8473697.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    97. Adaptive versus pathological plasticity. Possible contributions to age-related dementia. Adv Neurol. 1993; 59:35-45. Cotman CW, Pike CJ, Cummings BJ. PMID: 8420121.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    98. Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease. Neuroscience. 1992 Dec; 51(4):801-13. Su JH, Cummings BJ, Cotman CW. PMID: 1488123.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    99. Deposition of beta/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain. Proc Natl Acad Sci U S A. 1992 Nov 15; 89(22):10857-61. Kammesheidt A, Boyce FM, Spanoyannis AF, Cummings BJ, Ortegón M, Cotman C, Vaught JL, Neve RL. PMID: 1438289; PMCID: PMC50441.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    100. bFGF promotes the survival of entorhinal layer II neurons after perforant path axotomy. Brain Res. 1992 Sep 25; 591(2):271-6. Cummings BJ, Yee GJ, Cotman CW. PMID: 1446240.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    101. Gliotoxic actions of excitatory amino acids. Neuropharmacology. 1992 Sep; 31(9):899-907. Bridges RJ, Hatalski CG, Shim SN, Cummings BJ, Vijayan V, Kundi A, Cotman CW. PMID: 1436396.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    102. beta-Amyloid induces neuritic dystrophy in vitro: similarities with Alzheimer pathology. Neuroreport. 1992 Sep; 3(9):769-72. Pike CJ, Cummings BJ, Cotman CW. PMID: 1421135.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    103. Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease. Neuroscience. 1992 Jun; 48(4):763-77. Cummings BJ, Su JH, Geddes JW, Van Nostrand WE, Wagner SL, Cunningham DD, Cotman CW. PMID: 1378573.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    104. Fractures following limb-salvage surgery and adjuvant irradiation for soft-tissue sarcoma. Clin Orthop Relat Res. 1991 Oct; (271):265-71. Bell RS, O'Sullivan B, Nguyen C, Mahoney J, Langer F, Cummings B, Czitrom A, Catton C. PMID: 1914305.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    105. Wound healing complications in soft tissue sarcoma management: comparison of three treatment protocols. J Surg Oncol. 1991 Mar; 46(3):190-7. Bell RS, Mahoney J, O'Sullivan B, Nguyen C, Langer F, Cummings B, Catton C, Czitrom A, Fornasier VL. PMID: 2011032.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    106. Induction of basic fibroblast growth factor in Alzheimer's disease pathology. Neuroreport. 1990 Nov-Dec; 1(3-4):211-4. Gómez-Pinilla F, Cummings BJ, Cotman CW. PMID: 1717039.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
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