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Alachkar, Amal

TitleAssociate Adjunct Professor
InstitutionUniversity of California, Irvine
DepartmentPharmacology
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-2591
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Zhang Y, Liu Y, Wu L, Fan C, Wang Z, Zhang X, Alachkar A, Liang X, Civelli O. Receptor-specific crosstalk between prostanoid E receptor 3 and bombesin receptor subtype 3. FASEB J. 2018 Jan 22; fj201700337RR. PMID: 29401613.
      View in: PubMed
    2. Sanathara NM, Garau C, Alachkar A, Wang L, Wang Z, Nishimori K, Xu X, Civelli O. Melanin concentrating hormone modulates oxytocin-mediated marble burying. Neuropharmacology. 2018 Jan; 128:22-32. PMID: 28888943.
      View in: PubMed
    3. Wang L, Zhang Y, Wang Z, Gong N, Kweon TD, Vo B, Wang C, Zhang X, Chung JY, Alachkar A, Liang X, Luo DZ, Civelli O. The Antinociceptive Properties of the Corydalis yanhusuo Extract. PLoS One. 2016; 11(9):e0162875. PMID: 27622550; PMCID: PMC5021270.
      View in: PubMed, PubMed Central
    4. Alachkar A, Alhassen L, Wang Z, Wang L, Onouye K, Sanathara N, Civelli O. Inactivation of the melanin concentrating hormone system impairs maternal behavior. Eur Neuropsychopharmacol. 2016 11; 26(11):1826-1835. PMID: 27617778.
      View in: PubMed
    5. Wang L, Alachkar A, Sanathara N, Belluzzi JD, Wang Z, Civelli O. A Methionine-Induced Animal Model of Schizophrenia: Face and Predictive Validity. Int J Neuropsychopharmacol. 2015 May 19; 18(12). PMID: 25991655; PMCID: PMC4675974.
      View in: PubMed, PubMed Central
    6. Al Moustafa AE, Ghabreau L, Akil N, Rastam S, Alachkar A, Yasmeen A. High-Risk HPVs and Human Carcinomas in the Syrian Population. Front Oncol. 2014; 4:68. PMID: 24765613; PMCID: PMC3980109.
      View in: PubMed, PubMed Central
    7. Lajin B, Alachkar A, Alhaj Sakur A. Betaine significantly improves multiplex tetra-primer ARMS-PCR methods. Mol Biotechnol. 2013 Jul; 54(3):977-82. PMID: 23412968.
      View in: PubMed
    8. Lajin B, Alhaj Sakur A, Alachkar A. Association between polymorphisms in apoptotic genes and susceptibility for developing breast cancer in Syrian women. Breast Cancer Res Treat. 2013 Apr; 138(2):611-9. PMID: 23468244.
      View in: PubMed
    9. Mustafa OH, Hamzeh AR, Ghabreau L, Akil N, Almoustafa AE, Alachkar A. Allele Frequencies of the Epidermal Growth Factor Receptors Polymorphism R521K in Colorectal Cancer Patients and Healthy Subjects Indicate a Risk-Reducing Effect of K521 in Syrian Population. N Am J Med Sci. 2013 Mar; 5(3):202-6. PMID: 23626956; PMCID: PMC3632024.
      View in: PubMed, PubMed Central
    10. Lajin B, Alachkar A, Michati R, Alhaj Sakur A. Association between polymorphisms in the genes for tumor suppressor protein p53 and its regulator NAD(P)H: quinone oxidoreductase 1 (NQO1) and schizophrenia in a Syrian study cohort. Arch Med Res. 2013 Feb; 44(2):121-6. PMID: 23360829.
      View in: PubMed
    11. Lajin B, Alachkar A, Alhaj Sakur A. A quadruplex tetra-primer ARMS-PCR method for the simultaneous detection of TP53 Arg72Pro, IVS3 16bp Del/Ins and IVS6+62A>G, and NQO1 C609T polymorphisms. Gene. 2012 Aug 10; 504(2):268-73. PMID: 22633876.
      View in: PubMed
    12. Lajin B, Alhaj Sakur A, Michati R, Alachkar A. Association between MTHFR C677T and A1298C, and MTRR A66G polymorphisms and susceptibility to schizophrenia in a Syrian study cohort. Asian J Psychiatr. 2012 Jun; 5(2):144-9. PMID: 22813657.
      View in: PubMed
    13. Lajin B, Alhaj Sakur A, Ghabreau L, Alachkar A. Association of polymorphisms in one-carbon metabolizing genes with breast cancer risk in Syrian women. Tumour Biol. 2012 Aug; 33(4):1133-9. PMID: 22373582.
      View in: PubMed
    14. Lajin B, Hamzeh AR, Ghabreau L, Mohamed A, Al Moustafa AE, Alachkar A. Catechol-O-methyltransferase Val 108/158 Met polymorphism and breast cancer risk: a case control study in Syria. Breast Cancer. 2013 Jan; 20(1):62-6. PMID: 22124994.
      View in: PubMed
    15. Lajin B, Alachkar A, Sakur AA. Triplex tetra-primer ARMS-PCR method for the simultaneous detection of MTHFR c.677C>T and c.1298A>C, and MTRR c.66A>G polymorphisms of the folate-homocysteine metabolic pathway. Mol Cell Probes. 2012 Feb; 26(1):16-20. PMID: 22074746.
      View in: PubMed
    16. Al Moustafa AE, Yasmeen A, Alachkar A, Achkhar A. Src inhibitors are promising therapy molecules for human cervical carcinomas. Med Hypotheses. 2011 Nov; 77(5):812-4. PMID: 21864985.
      View in: PubMed
    17. Alachkar A, Brotchie JM, Jones OT. Changes in the mRNA levels of a2A and a2C adrenergic receptors in rat models of Parkinson's disease and L-DOPA-induced dyskinesia. J Mol Neurosci. 2012 Jan; 46(1):145-52. PMID: 21562737.
      View in: PubMed
    18. Lajin B, Alachkar A, Hamzeh AR, Michati R, Alhaj H. No association between Val158Met of the COMT gene and susceptibility to schizophrenia in the Syrian population. N Am J Med Sci. 2011 Apr; 3(4):176-8. PMID: 22540087; PMCID: PMC3336908.
      View in: PubMed, PubMed Central
    19. Alachkar A, Jaddouh A, Elsheikh MS, Bilia AR, Vincieri FF. Traditional medicine in Syria: folk medicine in Aleppo governorate. Nat Prod Commun. 2011 Jan; 6(1):79-84. PMID: 21366051.
      View in: PubMed
    20. Yasmeen A, Alachkar A, Dekhil H, Gambacorti-Passerini C, Al Moustafa AE. Locking Src/Abl Tyrosine Kinase Activities Regulate Cell Differentiation and Invasion of Human Cervical Cancer Cells Expressing E6/E7 Oncoproteins of High-Risk HPV. J Oncol. 2010; 2010. PMID: 20862378; PMCID: PMC2938462.
      View in: PubMed, PubMed Central
    21. Alachkar A, Brotchie JM, Jones OT. Locomotor response to L-DOPA in reserpine-treated rats following central inhibition of aromatic L-amino acid decarboxylase: further evidence for non-dopaminergic actions of L-DOPA and its metabolites. Neurosci Res. 2010 Sep; 68(1):44-50. PMID: 20542064.
      View in: PubMed
    22. Alachkar A, Brotchie JM, Jones OT. Binding of dopamine and 3-methoxytyramine as l-DOPA metabolites to human alpha(2)-adrenergic and dopaminergic receptors. Neurosci Res. 2010 Jul; 67(3):245-9. PMID: 20302892.
      View in: PubMed
    23. Kandouz M, Alachkar A, Zhang L, Dekhil H, Chehna F, Yasmeen A, Al Moustafa AE. Teucrium polium plant extract inhibits cell invasion and motility of human prostate cancer cells via the restoration of the E-cadherin/catenin complex. J Ethnopharmacol. 2010 Jun 16; 129(3):410-5. PMID: 19897022.
      View in: PubMed
    24. Alachkar A, Brotchie J, Jones OT. alpha2-Adrenoceptor-mediated modulation of the release of GABA and noradrenaline in the rat substantia nigra pars reticulata. Neurosci Lett. 2006 Mar 06; 395(2):138-42. PMID: 16356632.
      View in: PubMed
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