Olivier Civelli

Title(s)Professor, Pharmaceutical Sciences
SchoolSchool of Pharmacy and Pharmaceutical Sciences
Address101 Theory, Suite 100
Irvine CA 92697-3958
Phone(949) 824-2522, 4291
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    Other Positions
    Title(s)Professor, Developmental & Cell Biology

    Collapse Research 
    Collapse Research Activities and Funding
    Upstream control and downstream effects of NPS release
    NIH R21MH093521Sep 19, 2012 - Aug 31, 2014
    Role: Principal Investigator
    Role of Neuropeptide S in age-related cognitive decline
    NIH R21AG039863Apr 1, 2011 - Mar 31, 2014
    Role: Principal Investigator
    A novel neuropeptide system involved in drug abuse
    NIH R01DA024746Feb 1, 2010 - Jan 31, 2015
    Role: Principal Investigator
    High-Throughput Assay for G-Protein Coupled Receptors in Pain Research
    NIH R03DA026557Sep 1, 2008 - Feb 28, 2010
    Role: Principal Investigator
    High-throughput assays for GPCR in obesity research
    NIH R01DK070619Jun 1, 2005 - Nov 30, 2008
    Role: Principal Investigator
    Novel Glycoprotein Hormone-Like proteins
    NIH R01DK063001Apr 1, 2003 - Feb 28, 2008
    Role: Principal Investigator
    Characterization of two novel neuropeptides
    NIH R01MH060231Sep 1, 1999 - Sep 30, 2009
    Role: Principal Investigator
    NIH R01MH048991May 1, 1992 - Apr 30, 1996
    Role: Co-Principal Investigator
    NIH R03MH048728Apr 1, 1992 - Mar 31, 1994
    Role: Co-Principal Investigator
    NIH R01MH045614May 1, 1989 - Mar 31, 1992
    Role: Principal Investigator
    NIH R01DK037231Sep 1, 1985 - Sep 30, 1990
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dehydroepiandrosterone Sulfate (DHEAS) Is an Endogenous Kv7 Channel Modulator That Reduces Kv7/M-Current Suppression and Inflammatory Pain. J Neurosci. 2023 10 25; 43(43):7073-7083. Alhassen L, Alhassen W, Wong C, Sun Y, Xia Z, Civelli O, Hoshi N. PMID: 37648450; PMCID: PMC10601364.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Editorial: Neuropeptide GPCRs in neuroendocrinology, Volume II. Front Endocrinol (Lausanne). 2023; 14:1219530. Vaudry H, Schoofs L, Civelli O, Kojima M. PMID: 37415662; PMCID: PMC10321770.
      View in: PubMed   Mentions:    Fields:    
    3. Behavioral and neuro-functional consequences of eliminating the KCNQ3 GABA binding site in mice. Front Mol Neurosci. 2023; 16:1192628. Chen KJ, Yoshimura R, Edmundo CA, Truong TM, Civelli O, Alachkar A, Abbott GW. PMID: 37305551; PMCID: PMC10248464.
      View in: PubMed   Mentions:
    4. The Analgesic Properties of Corydalis yanhusuo. Molecules. 2021 Dec 10; 26(24). Alhassen L, Dabbous T, Ha A, Dang LHL, Civelli O. PMID: 34946576; PMCID: PMC8704877.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    5. Transcriptome Profiling of Dysregulated GPCRs Reveals Overlapping Patterns across Psychiatric Disorders and Age-Disease Interactions. Cells. 2021 10 31; 10(11). Monfared RV, Alhassen W, Truong TM, Gonzales MAM, Vachirakorntong V, Chen S, Baldi P, Civelli O, Alachkar A. PMID: 34831190; PMCID: PMC8616384.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    6. The Extract of Corydalis yanhusuo Prevents Morphine Tolerance and Dependence. Pharmaceuticals (Basel). 2021 Oct 12; 14(10). Alhassen L, Nuseir K, Ha A, Phan W, Marmouzi I, Shah S, Civelli O. PMID: 34681258; PMCID: PMC8540887.
      View in: PubMed   Mentions: 2  
    7. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. Br J Pharmacol. 2021 Oct; 178 Suppl 1:S27-S156. Alexander SP, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Abbracchio MP, Alexander W, Al-Hosaini K, Bäck M, Barnes NM, Bathgate R, Beaulieu JM, Bernstein KE, Bettler B, Birdsall NJM, Blaho V, Boulay F, Bousquet C, Bräuner-Osborne H, Burnstock G, Caló G, Castaño JP, Catt KJ, Ceruti S, Chazot P, Chiang N, Chini B, Chun J, Cianciulli A, Civelli O, Clapp LH, Couture R, Csaba Z, Dahlgren C, Dent G, Singh KD, Douglas SD, Dournaud P, Eguchi S, Escher E, Filardo EJ, Fong T, Fumagalli M, Gainetdinov RR, Gasparo M, Gerard C, Gershengorn M, Gobeil F, Goodfriend TL, Goudet C, Gregory KJ, Gundlach AL, Hamann J, Hanson J, Hauger RL, Hay DL, Heinemann A, Hollenberg MD, Holliday ND, Horiuchi M, Hoyer D, Hunyady L, Husain A, IJzerman AP, Inagami T, Jacobson KA, Jensen RT, Jockers R, Jonnalagadda D, Karnik S, Kaupmann K, Kemp J, Kennedy C, Kihara Y, Kitazawa T, Kozielewicz P, Kreienkamp HJ, Kukkonen JP, Langenhan T, Leach K, Lecca D, Lee JD, Leeman SE, Leprince J, Li XX, Williams TL, Lolait SJ, Lupp A, Macrae R, Maguire J, Mazella J, McArdle CA, Melmed S, Michel MC, Miller LJ, Mitolo V, Mouillac B, Müller CE, Murphy P, Nahon JL, Ngo T, Norel X, Nyimanu D, O'Carroll AM, Offermanns S, Panaro MA, Parmentier M, Pertwee RG, Pin JP, Prossnitz ER, Quinn M, Ramachandran R, Ray M, Reinscheid RK, Rondard P, Rovati GE, Ruzza C, Sanger GJ, Schöneberg T, Schulte G, Schulz S, Segaloff DL, Serhan CN, Stoddart LA, Sugimoto Y, Summers R, Tan VP, Thal D, Thomas WW, Timmermans PBMWM, Tirupula K, Tulipano G, Unal H, Unger T, Valant C, Vanderheyden P, Vaudry D, Vaudry H, Vilardaga JP, Walker CS, Wang JM, Ward DT, Wester HJ, Willars GB, Woodruff TM, Yao C, Ye RD. PMID: 34529832.
      View in: PubMed   Mentions: 103     Fields:    Translation:Humans
    8. Patterns of cilia gene dysregulations in major psychiatric disorders. Prog Neuropsychopharmacol Biol Psychiatry. 2021 07 13; 109:110255. Alhassen W, Chen S, Vawter M, Robbins BK, Nguyen H, Myint TN, Saito Y, Schulmann A, Nauli SM, Civelli O, Baldi P, Alachkar A. PMID: 33508383; PMCID: PMC9121176.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    9. Oxytocin-MCH circuit regulates monosynaptic inputs to MCH neurons and modulates social recognition memory. Neuropharmacology. 2021 02 15; 184:108423. Sanathara N, Alhassen L, Marmouzi I, Khoudari M, Phan J, Alhassen W, Civelli O, Alachkar A. PMID: 33290754.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    10. Melanin Concentrating Hormone Signaling Deficits in Schizophrenia: Association With Memory and Social Impairments and Abnormal Sensorimotor Gating. Int J Neuropsychopharmacol. 2020 03 10; 23(1):53-65. Vawter MP, Schulmann A, Alhassen L, Alhassen W, Hamzeh AR, Sakr J, Pauluk L, Yoshimura R, Wang X, Dai Q, Sanathara N, Civelli O, Alachkar A. PMID: 31563948; PMCID: PMC7442395.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    11. A Natural Product with High Affinity to Sigma and 5-HT7 Receptors as Novel Therapeutic Drug for Negative and Cognitive Symptoms of Schizophrenia. Neurochem Res. 2019 Nov; 44(11):2536-2545. Wang L, Zhang Y, Wang C, Zhang X, Wang Z, Liang X, Alachkar A, Civelli O. PMID: 31529334.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    12. Association of Myoinositol Transporters with Schizophrenia and Bipolar Disorder: Evidence from Human and Animal Studies. Mol Neuropsychiatry. 2019 Oct; 5(4):200-211. Vawter MP, Hamzeh AR, Muradyan E, Civelli O, Abbott GW, Alachkar A. PMID: 31768373; PMCID: PMC6873027.
      View in: PubMed   Mentions: 6  
    13. The role of Olfaction in MCH-regulated spontaneous maternal responses. Brain Res. 2019 09 15; 1719:71-76. Alhassen L, Phan A, Alhassen W, Nguyen P, Lo A, Shaharuddin H, Sanathara N, Civelli O, Alachkar A. PMID: 31121161.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    14. The History of N/OFQ and the NOP Receptor. Handb Exp Pharmacol. 2019; 254:3-16. Reinscheid RK, Civelli O. PMID: 30689090.
      View in: PubMed   Mentions: 1     Fields:    
    15. Receptor-specific crosstalk between prostanoid E receptor 3 and bombesin receptor subtype 3. FASEB J. 2018 06; 32(6):3184-3192. Zhang Y, Liu Y, Wu L, Fan C, Wang Z, Zhang X, Alachkar A, Liang X, Civelli O. PMID: 29401613; PMCID: PMC5956246.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    16. Melanin concentrating hormone modulates oxytocin-mediated marble burying. Neuropharmacology. 2018 Jan; 128:22-32. Sanathara NM, Garau C, Alachkar A, Wang L, Wang Z, Nishimori K, Xu X, Civelli O. PMID: 28888943; PMCID: PMC5830107.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    17. Prenatal one-carbon metabolism dysregulation programs schizophrenia-like deficits. Mol Psychiatry. 2018 02; 23(2):282-294. Alachkar A, Wang L, Yoshimura R, Hamzeh AR, Wang Z, Sanathara N, Lee SM, Xu X, Abbott GW, Civelli O. PMID: 28809400; PMCID: PMC6432924.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    18. The Antinociceptive Properties of the Corydalis yanhusuo Extract. PLoS One. 2016; 11(9):e0162875. Wang L, Zhang Y, Wang Z, Gong N, Kweon TD, Vo B, Wang C, Zhang X, Chung JY, Alachkar A, Liang X, Luo DZ, Civelli O. PMID: 27622550; PMCID: PMC5021270.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    19. Inactivation of the melanin concentrating hormone system impairs maternal behavior. Eur Neuropsychopharmacol. 2016 11; 26(11):1826-1835. Alachkar A, Alhassen L, Wang Z, Wang L, Onouye K, Sanathara N, Civelli O. PMID: 27617778; PMCID: PMC5929110.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    20. Hydroxycinnamic acid amides from Scopolia tangutica inhibit the activity of M1 muscarinic acetylcholine receptor in vitro. Fitoterapia. 2016 Jan; 108:9-12. Zhang Y, Long Z, Guo Z, Wang Z, Zhang X, Ye RD, Liang X, Civelli O. PMID: 26586621; PMCID: PMC4698058.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    21. A Methionine-Induced Animal Model of Schizophrenia: Face and Predictive Validity. Int J Neuropsychopharmacol. 2015 May 19; 18(12). Wang L, Alachkar A, Sanathara N, Belluzzi JD, Wang Z, Civelli O. PMID: 25991655; PMCID: PMC4675974.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    22. Amide alkaloids from Scopolia tangutica. Planta Med. 2014 Aug; 80(13):1124-30. Long Z, Zhang Y, Guo Z, Wang L, Xue X, Zhang X, Wang S, Wang Z, Civelli O, Liang X. PMID: 25127021.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    23. Discovery of N-methyltetrahydroprotoberberines with κ-opioid receptor agonists-opioid receptor agonist activities from corydalis yanhusuo W. T. Wang by using two-dimensional liquid chromatography. J Ethnopharmacol. 2014 Sep 29; 155(3):1597-602. Zhang Y, Wang C, Guo Z, Zhang X, Wang Z, Liang X, Civelli O. PMID: 25107388.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    24. Identification of neuropeptide receptors expressed by melanin-concentrating hormone neurons. J Comp Neurol. 2014 Dec 01; 522(17):3817-33. Parks GS, Wang L, Wang Z, Civelli O. PMID: 24978951; PMCID: PMC4167928.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    25. Histamine inhibits the melanin-concentrating hormone system: implications for sleep and arousal. J Physiol. 2014 May 15; 592(10):2183-96. Parks GS, Olivas ND, Ikrar T, Sanathara NM, Wang L, Wang Z, Civelli O, Xu X. PMID: 24639485; PMCID: PMC4227902.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    26. A novel analgesic isolated from a traditional Chinese medicine. Curr Biol. 2014 Jan 20; 24(2):117-123. Zhang Y, Wang C, Wang L, Parks GS, Zhang X, Guo Z, Ke Y, Li KW, Kim MK, Vo B, Borrelli E, Ge G, Yang L, Wang Z, Garcia-Fuster MJ, Luo ZD, Liang X, Civelli O. PMID: 24388848; PMCID: PMC3912990.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    27. Gait disorders in parkinsonian monkeys with pedunculopontine nucleus lesions: a tale of two systems. J Neurosci. 2013 Jul 17; 33(29):11986-93. Grabli D, Karachi C, Folgoas E, Monfort M, Tande D, Clark S, Civelli O, Hirsch EC, François C. PMID: 23864685; PMCID: PMC6794061.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    28. MCH and apomorphine in combination enhance action potential firing of nucleus accumbens shell neurons in vitro. PeerJ. 2013; 1:e61. Hopf FW, Seif T, Chung S, Civelli O. PMID: 23646281; PMCID: PMC3642701.
      View in: PubMed   Mentions: 5     Fields:    
    29. Anatomical characterization of bombesin receptor subtype-3 mRNA expression in the rodent central nervous system. J Comp Neurol. 2013 Apr 01; 521(5):1020-39. Zhang L, Parks GS, Wang Z, Wang L, Lew M, Civelli O. PMID: 22911445.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    30. Orphan GPCRs and neuromodulation. Neuron. 2012 Oct 04; 76(1):12-21. Civelli O. PMID: 23040803; PMCID: PMC3474844.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    31. Design, synthesis and SAR analysis of novel potent and selective small molecule antagonists of NPBWR1 (GPR7). Bioorg Med Chem Lett. 2012 Dec 01; 22(23):7135-41. Urbano M, Guerrero M, Zhao J, Velaparthi S, Saldanha SA, Chase P, Wang Z, Civelli O, Hodder P, Schaeffer MT, Brown S, Rosen H, Roberts E. PMID: 23079522; PMCID: PMC3601546.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    32. Disruption of the melanin-concentrating hormone receptor 1 (MCH1R) affects thyroid function. Endocrinology. 2012 Dec; 153(12):6145-54. Chung S, Liao XH, Di Cosmo C, Van Sande J, Wang Z, Refetoff S, Civelli O. PMID: 23024261; PMCID: PMC3512057.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    33. G protein-coupled receptor deorphanizations. Annu Rev Pharmacol Toxicol. 2013; 53:127-46. Civelli O, Reinscheid RK, Zhang Y, Wang Z, Fredriksson R, Schiöth HB. PMID: 23020293; PMCID: PMC5828024.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimals
    34. BmK-YA, an enkephalin-like peptide in scorpion venom. PLoS One. 2012; 7(7):e40417. Zhang Y, Xu J, Wang Z, Zhang X, Liang X, Civelli O. PMID: 22792309; PMCID: PMC3392217.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    35. The melanin-concentrating hormone (MCH) system in an animal model of depression-like behavior. Eur Neuropsychopharmacol. 2012 Aug; 22(8):607-13. García-Fuster MJ, Parks GS, Clinton SM, Watson SJ, Akil H, Civelli O. PMID: 22209364; PMCID: PMC3319808.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    36. Study on the activation of the opioid receptors by a set of morphine derivatives in a well-defined assay system. Neurochem Res. 2012 Feb; 37(2):410-6. Zhang Y, Wang Z, Cox DP, Civelli O. PMID: 22002663.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    37. The melanin-concentrating hormone (MCH) system modulates behaviors associated with psychiatric disorders. PLoS One. 2011; 6(7):e19286. Chung S, Verheij MM, Hesseling P, van Vugt RW, Buell M, Belluzzi JD, Geyer MA, Martens GJ, Civelli O. PMID: 21818251; PMCID: PMC3139593.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    38. Novel neuropeptides as ligands of orphan G protein-coupled receptors. Curr Pharm Des. 2011; 17(25):2626-31. Zhang Y, Wang Z, Parks GS, Civelli O. PMID: 21728976; PMCID: PMC5828022.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    39. Mice lacking Melanin Concentrating Hormone 1 receptor are resistant to seizures. Neurosci Lett. 2010 Oct 29; 484(2):104-7. Parks GS, Okumura SM, Gohil K, Civelli O. PMID: 20709149; PMCID: PMC2943056.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    40. Anxiolytic effects of the MCH1R antagonist TPI 1361-17. J Mol Neurosci. 2011 Feb; 43(2):132-7. Lee C, Parks GS, Civelli O. PMID: 20635163; PMCID: PMC3026772.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    41. Recent updates on the melanin-concentrating hormone (MCH) and its receptor system: lessons from MCH1R antagonists. J Mol Neurosci. 2011 Jan; 43(1):115-21. Chung S, Parks GS, Lee C, Civelli O. PMID: 20582487; PMCID: PMC3018593.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    42. Acute homeostatic responses to increased fat consumption in MCH1R knockout mice. J Mol Neurosci. 2010 Nov; 42(3):459-63. Chung S, Wong T, Nagasaki H, Civelli O. PMID: 20411353; PMCID: PMC2955453.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    43. MCH receptors/gene structure-in vivo expression. Peptides. 2009 Nov; 30(11):1985-9. Chung S, Saito Y, Civelli O. PMID: 19647772; PMCID: PMC2764003.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    44. Pharmacological characterization of a selective agonist for bombesin receptor subtype-3. Biochem Biophys Res Commun. 2009 Sep 18; 387(2):283-8. Zhang L, Nothacker HP, Wang Z, Bohn LM, Civelli O. PMID: 19580790; PMCID: PMC2747518.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    45. The melanin-concentrating hormone system modulates cocaine reward. Proc Natl Acad Sci U S A. 2009 Apr 21; 106(16):6772-7. Chung S, Hopf FW, Nagasaki H, Li CY, Belluzzi JD, Bonci A, Civelli O. PMID: 19342492; PMCID: PMC2672513.
      View in: PubMed   Mentions: 71     Fields:    Translation:Animals
    46. The pharmacological properties of a novel MCH1 receptor antagonist isolated from combinatorial libraries. Eur J Pharmacol. 2009 Jan 14; 602(2-3):194-202. Nagasaki H, Chung S, Dooley CT, Wang Z, Li C, Saito Y, Clark SD, Houghten RA, Civelli O. PMID: 19041642; PMCID: PMC2633472.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    47. Biochemical roles of the oligosaccharide chains in thyrostimulin, a heterodimeric hormone of glycoprotein hormone subunits alpha 2 (GPA2) and beta 5 (GPB5). Regul Pept. 2008 Jun 05; 148(1-3):62-7. Okajima Y, Nagasaki H, Suzuki C, Suga H, Ozaki N, Arima H, Hamada Y, Civelli O, Oiso Y. PMID: 18433898.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    48. Orphan G protein-coupled receptors and novel neuropeptides. Introduction. Results Probl Cell Differ. 2008; 46:v-vi. Civelli O, Zhou QY. PMID: 18634199.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    49. The orphanin FQ/nociceptin (OFQ/N) system. Results Probl Cell Differ. 2008; 46:1-25. Civelli O. PMID: 18193175.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    50. Orphan GPCR research. Br J Pharmacol. 2008 Mar; 153 Suppl 1:S339-46. Chung S, Funakoshi T, Civelli O. PMID: 18071299; PMCID: PMC2268047.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    51. Fusion of diphtheria toxin and urotensin II produces a neurotoxin selective for cholinergic neurons in the rat mesopontine tegmentum. J Neurochem. 2007 Jul; 102(1):112-20. Clark SD, Alderson HL, Winn P, Latimer MP, Nothacker HP, Civelli O. PMID: 17419804.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    52. A Drosophila adenosine receptor activates cAMP and calcium signaling. Insect Biochem Mol Biol. 2007 Apr; 37(4):318-29. Dolezelova E, Nothacker HP, Civelli O, Bryant PJ, Zurovec M. PMID: 17368195.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    53. Orphanin FQ/nociceptin interacts with the basolateral amygdala noradrenergic system in memory consolidation. Learn Mem. 2007 Jan-Feb; 14(1-2):29-35. Roozendaal B, Lengvilas R, McGaugh JL, Civelli O, Reinscheid RK. PMID: 17202427; PMCID: PMC1838543.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    54. Distribution of neuropeptide S receptor mRNA and neurochemical characteristics of neuropeptide S-expressing neurons in the rat brain. J Comp Neurol. 2007 Jan 01; 500(1):84-102. Xu YL, Gall CM, Jackson VR, Civelli O, Reinscheid RK. PMID: 17099900.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    55. Differential expression of the thyrostimulin subunits, glycoprotein alpha2 and beta5 in the rat pituitary. J Mol Endocrinol. 2006 Aug; 37(1):39-50. Nagasaki H, Wang Z, Jackson VR, Lin S, Nothacker HP, Civelli O. PMID: 16901922.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    56. A study of the rat neuropeptide B/neuropeptide W system using in situ techniques. J Comp Neurol. 2006 Jul 20; 497(3):367-83. Jackson VR, Lin SH, Wang Z, Nothacker HP, Civelli O. PMID: 16736466.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    57. Orphan neuropeptides. Novel neuropeptides modulating sleep or feeding. Neuropeptides. 2006 Aug; 40(4):233-43. Chung S, Civelli O. PMID: 16814380.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    58. GPR39 receptor expression in the mouse brain. Neuroreport. 2006 May 29; 17(8):813-6. Jackson VR, Nothacker HP, Civelli O. PMID: 16708020.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    59. Salusin beta is a surrogate ligand of the mas-like G protein-coupled receptor MrgA1. Eur J Pharmacol. 2006 Jun 13; 539(3):145-50. Wang Z, Takahashi T, Saito Y, Nagasaki H, Ly NK, Nothacker HP, Reinscheid RK, Yang J, Chang JK, Shichiri M, Civelli O. PMID: 16697365.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    60. Endogenous orphanin FQ/nociceptin is involved in the development of morphine tolerance. J Pharmacol Exp Ther. 2006 Jul; 318(1):262-7. Chung S, Pohl S, Zeng J, Civelli O, Reinscheid RK. PMID: 16595734.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    61. The opioid peptide nociceptin/orphanin FQ mediates prostaglandin E2-induced allodynia, tactile pain associated with nerve injury. Eur J Neurosci. 2006 Feb; 23(4):995-1004. Okuda-Ashitaka E, Minami T, Matsumura S, Takeshima H, Reinscheid RK, Civelli O, Ito S. PMID: 16519664.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    62. Orphan GPCRs and their ligands. Pharmacol Ther. 2006 Jun; 110(3):525-32. Civelli O, Saito Y, Wang Z, Nothacker HP, Reinscheid RK. PMID: 16289308.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    63. Cancer metastasis-suppressing peptide metastin upregulates excitatory synaptic transmission in hippocampal dentate granule cells. J Neurophysiol. 2005 Nov; 94(5):3648-52. Arai AC, Xia YF, Suzuki E, Kessler M, Civelli O, Nothacker HP. PMID: 16222076.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    64. Orphan GPCRs in the regulation of sleep and circadian rhythm. FEBS J. 2005 Nov; 272(22):5673-4. Civelli O. PMID: 16279932.
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    65. Urotensin II acts as a modulator of mesopontine cholinergic neurons. Brain Res. 2005 Oct 19; 1059(2):139-48. Clark SD, Nothacker HP, Blaha CD, Tyler CJ, Duangdao DM, Grupke SL, Helton DR, Leonard CS, Civelli O. PMID: 16183039.
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    66. Pharmacological characterization of human and murine neuropeptide s receptor variants. J Pharmacol Exp Ther. 2005 Dec; 315(3):1338-45. Reinscheid RK, Xu YL, Okamura N, Zeng J, Chung S, Pai R, Wang Z, Civelli O. PMID: 16144971.
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    67. Proadrenomedullin N-terminal peptide and cortistatin activation of MrgX2 receptor is based on a common structural motif. Eur J Pharmacol. 2005 Sep 05; 519(1-2):191-3. Nothacker HP, Wang Z, Zeng H, Mahata SK, O'Connor DT, Civelli O. PMID: 16111673.
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    68. Urotensin II modulates rapid eye movement sleep through activation of brainstem cholinergic neurons. J Neurosci. 2005 Jun 08; 25(23):5465-74. Huitron-Resendiz S, Kristensen MP, Sánchez-Alavez M, Clark SD, Grupke SL, Tyler C, Suzuki C, Nothacker HP, Civelli O, Criado JR, Henriksen SJ, Leonard CS, de Lecea L. PMID: 15944374; PMCID: PMC6724976.
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    69. Neuropeptide S: a new player in the modulation of arousal and anxiety. Mol Interv. 2005 Feb; 5(1):42-6. Reinscheid RK, Xu YL, Civelli O. PMID: 15731503.
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    70. GPCR deorphanizations: the novel, the known and the unexpected transmitters. Trends Pharmacol Sci. 2005 Jan; 26(1):15-9. Civelli O. PMID: 15629200.
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    71. G-protein-coupled receptor deorphanizations. Int Rev Neurobiol. 2005; 65:179-209. Saito Y, Civelli O. PMID: 16140057.
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    72. An orphan receptor adopted by a family of transmitters. Mol Pharmacol. 2005 Mar; 67(3):583-4. Civelli O. PMID: 15604412.
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    73. Orphan G protein-coupled receptors and obesity. Eur J Pharmacol. 2004 Oct 01; 500(1-3):243-53. Xu YL, Jackson VR, Civelli O. PMID: 15464037.
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    74. Neuropeptide S: a neuropeptide promoting arousal and anxiolytic-like effects. Neuron. 2004 Aug 19; 43(4):487-97. Xu YL, Reinscheid RK, Huitron-Resendiz S, Clark SD, Wang Z, Lin SH, Brucher FA, Zeng J, Ly NK, Henriksen SJ, de Lecea L, Civelli O. PMID: 15312648.
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    75. Orphan G protein-coupled receptors: targets for new therapeutic interventions. Ann Med. 2004; 36(3):204-14. Lin SH, Civelli O. PMID: 15181976.
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    76. High-throughput real-time monitoring of Gs-coupled receptor activation in intact cells using cyclic nucleotide-gated channels. Eur J Pharmacol. 2003 Sep 30; 478(1):27-34. Reinscheid RK, Kim J, Zeng J, Civelli O. PMID: 14555181.
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    77. Different structural requirements for melanin-concentrating hormone (MCH) interacting with rat MCH-R1 (SLC-1) and mouse B16 cell MCH-R. J Recept Signal Transduct Res. 2003 Feb; 23(1):69-81. Schlumberger SE, Saito Y, Giller T, Hintermann E, Tanner H, Jäggin V, Zumsteg U, Civelli O, Eberle AN. PMID: 12680590.
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    78. The urotensin II receptor is expressed in the cholinergic mesopontine tegmentum of the rat. Brain Res. 2001 Dec 27; 923(1-2):120-7. Clark SD, Nothacker HP, Wang Z, Saito Y, Leslie FM, Civelli O. PMID: 11743979.
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    79. Endogenous melanin-concentrating hormone receptor SLC-1 in human melanoma SK-MEL-37 cells. Biochem Biophys Res Commun. 2001 Nov 23; 289(1):44-50. Saito Y, Wang Z, Hagino-Yamagishi K, Civelli O, Kawashima S, Maruyama K. PMID: 11708774.
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    80. The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering. Mol Pharmacol. 2001 Nov; 60(5):916-23. Lin SH, Arai AC, Wang Z, Nothacker HP, Civelli O. PMID: 11641419.
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    81. Expression of the melanin-concentrating hormone (MCH) receptor mRNA in the rat brain. J Comp Neurol. 2001 Jun 18; 435(1):26-40. Saito Y, Cheng M, Leslie FM, Civelli O. PMID: 11370009.
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    82. Novel neurotransmitters as natural ligands of orphan G-protein-coupled receptors. Trends Neurosci. 2001 Apr; 24(4):230-7. Civelli O, Nothacker HP, Saito Y, Wang Z, Lin SH, Reinscheid RK. PMID: 11250008.
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    83. Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: discovery of a subtype selective agonist. Mol Pharmacol. 2000 Dec; 58(6):1601-8. Nothacker HP, Wang Z, Zhu Y, Reinscheid RK, Lin SH, Civelli O. PMID: 11093801.
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    84. Melanin-concentrating hormone receptor: an orphan receptor fits the key. Trends Endocrinol Metab. 2000 Oct; 11(8):299-303. Saito Y, Nothacker HP, Civelli O. PMID: 10996523.
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    85. The orphanin FQ/nociceptin gene: structure, tissue distribution of expression and functional implications obtained from knockout mice. Peptides. 2000 Jul; 21(7):901-6. Reinscheid RK, Nothacker H, Civelli O. PMID: 10998523.
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    86. Orphan receptors, novel neuropeptides and reverse pharmaceutical research. Brain Res. 1999 Nov 27; 848(1-2):63-5. Civelli O, Reinscheid RK, Nothacker HP. PMID: 10612697.
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    87. Opioid receptor-like (ORL1) receptor distribution in the rat central nervous system: comparison of ORL1 receptor mRNA expression with (125)I-[(14)Tyr]-orphanin FQ binding. J Comp Neurol. 1999 Oct 04; 412(4):563-605. Neal CR, Mansour A, Reinscheid R, Nothacker HP, Civelli O, Akil H, Watson SJ. PMID: 10464356.
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    88. Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction. Nat Cell Biol. 1999 Oct; 1(6):383-5. Nothacker HP, Wang Z, McNeill AM, Saito Y, Merten S, O'Dowd B, Duckles SP, Civelli O. PMID: 10559967.
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    89. Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice. Proc Natl Acad Sci U S A. 1999 Aug 31; 96(18):10444-9. Köster A, Montkowski A, Schulz S, Stübe EM, Knaudt K, Jenck F, Moreau JL, Nothacker HP, Civelli O, Reinscheid RK. PMID: 10468628; PMCID: PMC17908.
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    90. Molecular characterization of the melanin-concentrating-hormone receptor. Nature. 1999 Jul 15; 400(6741):265-9. Saito Y, Nothacker HP, Wang Z, Lin SH, Leslie F, Civelli O. PMID: 10421368.
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    91. Localization of orphanin FQ (nociceptin) peptide and messenger RNA in the central nervous system of the rat. J Comp Neurol. 1999 Apr 19; 406(4):503-47. Neal CR, Mansour A, Reinscheid R, Nothacker HP, Civelli O, Watson SJ. PMID: 10205026.
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    92. Orphan receptors and the concept of reverse physiology: discovery of the novel neuropeptide orphanin FQ/nociceptin. Results Probl Cell Differ. 1999; 26:193-214. Reinscheid RK, Nothacker HP, Civelli O. PMID: 10453465.
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    93. Functional genomics: the search for novel neurotransmitters and neuropeptides. FEBS Lett. 1998 Jun 23; 430(1-2):55-8. Civelli O. PMID: 9678594.
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    94. Creating a functional opioid alkaloid binding site in the orphanin FQ receptor through site-directed mutagenesis. Mol Pharmacol. 1998 Apr; 53(4):772-7. Meng F, Ueda Y, Hoversten MT, Taylor LP, Reinscheid RK, Monsma FJ, Watson SJ, Civelli O, Akil H. PMID: 9547370.
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    95. Adenosine A1 receptor-mediated modulation of dopamine D1 receptors in stably cotransfected fibroblast cells. J Biol Chem. 1998 Feb 20; 273(8):4718-24. Ferré S, Torvinen M, Antoniou K, Irenius E, Civelli O, Arenas E, Fredholm BB, Fuxe K. PMID: 9468534.
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    96. Development and characterization of antibodies directed against the mouse D4 dopamine receptor. Eur J Neurosci. 1998 Feb; 10(2):529-37. Mauger C, Sivan B, Brockhaus M, Fuchs S, Civelli O, Monsma F. PMID: 9749715.
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    97. Expression and characterization of a dopamine D4R variant associated with delusional disorder. FEBS Lett. 1998 Jan 30; 422(2):146-50. Zenner MT, Nobile M, Henningsen R, Smeraldi E, Civelli O, Hartman DS, Catalano M. PMID: 9489994.
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    98. Structures that delineate orphanin FQ and dynorphin A pharmacological selectivities. J Biol Chem. 1998 Jan 16; 273(3):1490-5. Reinscheid RK, Higelin J, Henningsen RA, Monsma FJ, Civelli O. PMID: 9430687.
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    99. Reverse physiology: discovery of the novel neuropeptide, orphanin FQ/nociceptin. Crit Rev Neurobiol. 1998; 12(3):163-76. Civelli O, Nothacker HP, Reinscheid R. PMID: 9847053.
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    100. Orphanin FQ acts as an anxiolytic to attenuate behavioral responses to stress. Proc Natl Acad Sci U S A. 1997 Dec 23; 94(26):14854-8. Jenck F, Moreau JL, Martin JR, Kilpatrick GJ, Reinscheid RK, Monsma FJ, Nothacker HP, Civelli O. PMID: 9405703; PMCID: PMC25127.
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    101. Interaction of [3H]orphanin FQ and 125I-Tyr14-orphanin FQ with the orphanin FQ receptor: kinetics and modulation by cations and guanine nucleotides. Mol Pharmacol. 1997 May; 51(5):816-24. Ardati A, Henningsen RA, Higelin J, Reinscheid RK, Civelli O, Monsma FJ. PMID: 9145920.
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    102. Epinephrine and norepinephrine act as potent agonists at the recombinant human dopamine D4 receptor. J Neurochem. 1997 Feb; 68(2):804-12. Lanau F, Zenner MT, Civelli O, Hartman DS. PMID: 9003072.
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    103. Orphan receptors and their natural ligands. J Recept Signal Transduct Res. 1997 Jan-May; 17(1-3):545-50. Civelli O, Nothacker HP, Bourson A, Ardati A, Monsma F, Reinscheid R. PMID: 9029514.
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    106. Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons. J Neurosci. 1996 Nov 01; 16(21):6657-64. Knoflach F, Reinscheid RK, Civelli O, Kemp JA. PMID: 8824306; PMCID: PMC6579277.
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    107. Orphanin FQ is a functional anti-opioid peptide. Neuroscience. 1996 Nov; 75(2):333-7. Mogil JS, Grisel JE, Reinscheid RK, Civelli O, Belknap JK, Grandy DK. PMID: 8930999.
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    108. Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ. Neurochem Res. 1996 Nov; 21(11):1387-96. Devine DP, Taylor L, Reinscheid RK, Monsma FJ, Civelli O, Akil H. PMID: 8947929.
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    109. Primary structure and tissue distribution of the orphanin FQ precursor. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8677-82. Nothacker HP, Reinscheid RK, Mansour A, Henningsen RA, Ardati A, Monsma FJ, Watson SJ, Civelli O. PMID: 8710930; PMCID: PMC38732.
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    112. Molecular attributes of dopamine receptors: new potential for antipsychotic drug development. Ann Med. 1996 Jun; 28(3):211-9. Hartman DS, Civelli O. PMID: 8811164.
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    118. Evidence that stimulatory dopamine receptors may be involved in the regulation of prolactin secretion. Endocrinology. 1994 Mar; 134(3):1263-8. Porter TE, Grandy D, Bunzow J, Wiles CD, Civelli O, Frawley LS. PMID: 8119166.
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    119. The somatostatin receptors SSTR1 and SSTR2 are coupled to inhibition of adenylyl cyclase in Chinese hamster ovary cells via pertussis toxin-sensitive pathways. Endocrinology. 1994 Mar; 134(3):1277-85. Hershberger RE, Newman BL, Florio T, Bunzow J, Civelli O, Li XJ, Forte M, Stork PJ. PMID: 7907016.
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    122. Exclusion of close linkage of Tourette's syndrome to D1 dopamine receptor. Am J Psychiatry. 1993 Mar; 150(3):449-53. Gelernter J, Kennedy JL, Grandy DK, Zhou QY, Civelli O, Pauls DL, Pakstis A, Kurlan R, Sunahara RK, Niznik HB, et al. PMID: 8434661.
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    123. Dopaminergic activity measured in D1- and D2-transfected fibroblasts by silicon-microphysiometry. J Recept Res. 1993; 13(1-4):559-71. Bouvier C, Salon JA, Johnson RA, Civelli O. PMID: 8450504.
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    124. Molecular diversity of the dopamine receptors. Annu Rev Pharmacol Toxicol. 1993; 33:281-307. Civelli O, Bunzow JR, Grandy DK. PMID: 8494342.
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    130. Distribution of D5 dopamine receptor mRNA in rat brain. Neurosci Lett. 1992 Oct 12; 145(2):209-12. Meador-Woodruff JH, Mansour A, Grandy DK, Damask SP, Civelli O, Watson SJ. PMID: 1465219.
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    138. Nucleotide and deduced amino acid sequence of bovine adrenal medulla chromogranin B (secretogranin I). Cell Mol Neurobiol. 1992 Apr; 12(2):185-92. Grandy DK, Leduc R, Makam H, Flanagan T, Diliberto EJ, Civelli O, Viveros OH. PMID: 1350945.
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    142. The diversity of the dopamine receptors. NIDA Res Monogr. 1992; 126:23-33. Civelli O, Bunzow JR, Zhou QY, Grandy DK. PMID: 1491715.
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    144. Comparison of the distributions of D1 and D2 dopamine receptor mRNAs in rat brain. Neuropsychopharmacology. 1991 Dec; 5(4):231-42. Meador-Woodruff JH, Mansour A, Healy DJ, Kuehn R, Zhou QY, Bunzow JR, Akil H, Civelli O, Watson SJ. PMID: 1839499.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    145. Multiple human D5 dopamine receptor genes: a functional receptor and two pseudogenes. Proc Natl Acad Sci U S A. 1991 Oct 15; 88(20):9175-9. Grandy DK, Zhang YA, Bouvier C, Zhou QY, Johnson RA, Allen L, Buck K, Bunzow JR, Salon J, Civelli O. PMID: 1833775; PMCID: PMC52675.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    146. Direct sequencing of the dopamine D2 receptor (DRD2) in schizophrenics reveals three polymorphisms but no structural change in the receptor. Genomics. 1991 Sep; 11(1):8-14. Sarkar G, Kapelner S, Grandy DK, Marchionni M, Civelli O, Sobell J, Heston L, Sommer SS. PMID: 1837284.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    147. Molecular biology of the dopamine receptors. Eur J Pharmacol. 1991 Aug 14; 207(4):277-86. Civelli O, Bunzow JR, Grandy DK, Zhou QY, Van Tol HH. PMID: 1783000.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    148. No linkage between D2 dopamine receptor gene region and schizophrenia. Arch Gen Psychiatry. 1991 Jul; 48(7):643-7. Moises HW, Gelernter J, Giuffra LA, Zarcone V, Wetterberg L, Civelli O, Kidd KK, Cavalli-Sforza LL, Grandy DK, Kennedy JL, et al. PMID: 2069495.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    149. Detection and characterization of additional DNA polymorphisms in the dopamine D2 receptor gene. Genomics. 1991 Jul; 10(3):527-30. Hauge XY, Grandy DK, Eubanks JH, Evans GA, Civelli O, Litt M. PMID: 1679742.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    150. A TaqI RFLP at the DRD1 locus. Nucleic Acids Res. 1991 Jun 11; 19(11):3161. Litt M, al-Dhalimy M, Zhou Q, Grandy D, Civelli O. PMID: 1676155; PMCID: PMC328299.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    151. Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature. 1991 Apr 18; 350(6319):610-4. Van Tol HH, Bunzow JR, Guan HC, Sunahara RK, Seeman P, Niznik HB, Civelli O. PMID: 1840645.
      View in: PubMed   Mentions: 312     Fields:    Translation:HumansAnimalsCells
    152. A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques. Neuroscience. 1991; 45(2):359-71. Mansour A, Meador-Woodruff JH, Zhou QY, Civelli O, Akil H, Watson SJ. PMID: 1762683.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    153. Regulation of responsiveness at D2 dopamine receptors by receptor desensitization and adenylyl cyclase sensitization. Mol Pharmacol. 1991 Jan; 39(1):55-63. Bates MD, Senogles SE, Bunzow JR, Liggett SB, Civelli O, Caron MG. PMID: 1846220.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    154. Distribution of D2 dopamine receptor mRNA in the primate brain. Prog Neuropsychopharmacol Biol Psychiatry. 1991; 15(6):885-93. Meador-Woodruff JH, Mansour A, Civelli O, Watson SJ. PMID: 1837159.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    155. Molecular biology of the dopamine D2 receptor. NIDA Res Monogr. 1991; 111:45-53. Civelli O, Bunzow J, Albert P, Van Tol H, Grandy D. PMID: 1837843.
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    156. Gilles de la Tourette syndrome is not linked to D2-dopamine receptor. Arch Gen Psychiatry. 1990 Nov; 47(11):1073-7. Gelernter J, Pakstis AJ, Pauls DL, Kurlan R, Gancher ST, Civelli O, Grandy D, Kidd KK. PMID: 1978653.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    157. A human D1 dopamine receptor gene is located on chromosome 5 at q35.1 and identifies an EcoRI RFLP. Am J Hum Genet. 1990 Nov; 47(5):828-34. Grandy DK, Zhou QY, Allen L, Litt R, Magenis RE, Civelli O, Litt M. PMID: 1977312; PMCID: PMC1683700.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    158. Cloning and expression of human and rat D1 dopamine receptors. Nature. 1990 Sep 06; 347(6288):76-80. Zhou QY, Grandy DK, Thambi L, Kushner JA, Van Tol HH, Cone R, Pribnow D, Salon J, Bunzow JR, Civelli O. PMID: 2168520.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    159. Purification, cloning, and tissue distribution of a 23-kDa rat protein isolated by morphine affinity chromatography. Mol Endocrinol. 1990 Sep; 4(9):1370-6. Grandy DK, Hanneman E, Bunzow J, Shih M, Machida CA, Bidlack JM, Civelli O. PMID: 1978248.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    160. Molecular cloning and expression of the rat beta 1-adrenergic receptor gene. J Biol Chem. 1990 Aug 05; 265(22):12960-5. Machida CA, Bunzow JR, Searles RP, Van Tol H, Tester B, Neve KA, Teal P, Nipper V, Civelli O. PMID: 1695899.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    161. Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization-receptor autoradiographic analysis. J Neurosci. 1990 Aug; 10(8):2587-600. Mansour A, Meador-Woodruff JH, Bunzow JR, Civelli O, Akil H, Watson SJ. PMID: 2143777; PMCID: PMC6570265.
      View in: PubMed   Mentions: 96     Fields:    Translation:AnimalsCells
    162. Differential coupling of dopaminergic D2 receptors expressed in different cell types. Stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis in LtK- fibroblasts, hyperpolarization, and cytosolic-free Ca2+ concentration decrease in GH4C1 cells. J Biol Chem. 1990 Jun 25; 265(18):10320-6. Vallar L, Muca C, Magni M, Albert P, Bunzow J, Meldolesi J, Civelli O. PMID: 2162345.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    163. Molecular characterization of dopamine receptors. Am J Hypertens. 1990 Jun; 3(6 Pt 2):29S-33S. Bates MD, Gingrich JA, Bunzow JR, Falardeau P, Dearry A, Senogles SE, Civelli O, Caron MG. PMID: 2143386.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    164. Lack of effect of chronic dopamine receptor blockade on D2 dopamine receptor mRNA level. Neurosci Lett. 1990 Apr 06; 111(3):303-8. van Tol HH, Riva M, Civelli O, Creese I. PMID: 1970862.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    165. Cloning, functional expression, and mRNA tissue distribution of the rat 5-hydroxytryptamine1A receptor gene. J Biol Chem. 1990 Apr 05; 265(10):5825-32. Albert PR, Zhou QY, Van Tol HH, Bunzow JR, Civelli O. PMID: 2156831.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    166. Coupling of a cloned rat dopamine-D2 receptor to inhibition of adenylyl cyclase and prolactin secretion. J Biol Chem. 1990 Feb 05; 265(4):2098-104. Albert PR, Neve KA, Bunzow JR, Civelli O. PMID: 1688845.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    167. The effects of nigrostriatal 6-hydroxydopamine lesions on dopamine D2 receptor mRNA and opioid systems. Prog Clin Biol Res. 1990; 328:227-30. Mansour A, Meador-Woodruff JH, Camp DM, Robinson TE, Bunzow J, Van Tol H, Civelli O, Akil H, Watson SJ. PMID: 2106148.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    168. Genetic linkage is excluded for the D2-dopamine receptor lambda HD2G1 and flanking loci on chromosome 11q22-q23 in Tourette syndrome. Hum Hered. 1990; 40(2):105-8. Devor EJ, Grandy DK, Civelli O, Litt M, Burgess AK, Isenberg KE, van de Wetering BJ, Oostra B. PMID: 2335364.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    169. The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP. Am J Hum Genet. 1989 Nov; 45(5):778-85. Grandy DK, Litt M, Allen L, Bunzow JR, Marchionni M, Makam H, Reed L, Magenis RE, Civelli O. PMID: 2573278; PMCID: PMC1683432.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    170. Distribution of D2 dopamine receptor mRNA in rat brain. Proc Natl Acad Sci U S A. 1989 Oct; 86(19):7625-8. Meador-Woodruff JH, Mansour A, Bunzow JR, Van Tol HH, Watson SJ, Civelli O. PMID: 2529545; PMCID: PMC298119.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    171. Functional characterization of a rat dopamine D-2 receptor cDNA expressed in a mammalian cell line. Mol Pharmacol. 1989 Sep; 36(3):446-51. Neve KA, Henningsen RA, Bunzow JR, Civelli O. PMID: 2571073.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    172. Replica filter screening technique to detect transfected cells expressing beta 2-adrenergic receptor. DNA. 1989 Jul-Aug; 8(6):447-55. Machida CA, Bunzow J, Hanneman E, Grandy D, Civelli O. PMID: 2550194.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    173. Cloning and expression of a rat D2 dopamine receptor cDNA. Nature. 1988 Dec 22-29; 336(6201):783-7. Bunzow JR, Van Tol HH, Grandy DK, Albert P, Salon J, Christie M, Machida CA, Neve KA, Civelli O. PMID: 2974511.
      View in: PubMed   Mentions: 168     Fields:    Translation:AnimalsCells
    174. Regulation of hypothalamic magnocellular neuropeptides and their mRNAs in the Brattleboro rat: coordinate responses to further osmotic challenge. J Neurosci. 1988 Oct; 8(10):3785-96. Sherman TG, Day R, Civelli O, Douglass J, Herbert E, Akil H, Watson SJ. PMID: 2903913; PMCID: PMC6569603.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    175. Differential activation of spinal cord dynorphin and enkephalin neurons during hyperalgesia: evidence using cDNA hybridization. Brain Res. 1988 Jul 12; 455(2):205-12. Iadarola MJ, Douglass J, Civelli O, Naranjo JR. PMID: 2900057.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    176. Lithium increases dynorphin A(1-8) and prodynorphin mRNA levels in the basal ganglia of rats. Brain Res. 1988 Apr; 427(2):155-63. Sivam SP, Takeuchi K, Li S, Douglass J, Civelli O, Calvetta L, Herbert E, McGinty JF, Hong JS. PMID: 2898269.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    177. Three technical approaches for cloning opioid receptors. NIDA Res Monogr. 1988; 87:93-110. Machida CA, Salon J, Grandy D, Bunzow J, Albert P, Hanneman E, Civelli O. PMID: 2855100.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    178. Expression of the prodynorphin gene in male and female mammalian reproductive tissues. Endocrinology. 1987 Feb; 120(2):707-13. Douglass J, Cox B, Quinn B, Civelli O, Herbert E. PMID: 2879723.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    179. The next frontier in the molecular biology of the opioid system. The opioid receptors. Mol Neurobiol. 1987; 1(4):373-91. Civelli O, Machida C, Bunzow J, Albert P, Hanneman E, Salon J, Bidlack J, Grandy D. PMID: 2855792.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    180. Pro-dynorphin is endogenous to the anterior pituitary and is co-localized with LH and FSH in the gonadotrophs. Endocrinology. 1986 Sep; 119(3):1409-11. Khachaturian H, Sherman TG, Lloyd RV, Civelli O, Douglass J, Herbert E, Akil H, Watson SJ. PMID: 3089769.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    181. Hypothalamic dynorphin and vasopressin mRNA expression in normal and Brattleboro rats. Fed Proc. 1986 Aug; 45(9):2323-7. Sherman TG, Civelli O, Douglass J, Herbert E, Burke S, Watson SJ. PMID: 2874054.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    182. Increased spinal cord dynorphin mRNA during peripheral inflammation. NIDA Res Monogr. 1986; 75:406-9. Iadarola MJ, Douglass J, Civelli O, Naranjo JR. PMID: 2893274.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    183. Coordinate expression of hypothalamic pro-dynorphin and pro-vasopressin mRNAs with osmotic stimulation. Neuroendocrinology. 1986; 44(2):222-8. Sherman TG, Civelli O, Douglass J, Herbert E, Watson SJ. PMID: 2432438.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    184. Biosynthesis of opioid peptides. NIDA Res Monogr. 1986; 70:21-42. Civelli O, Douglass J, Rosen H, Martens G, Herbert E. PMID: 3093878.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    185. Nucleotide sequence of cloned cDNA for pro-opiomelanocortin in the amphibian Xenopus laevis. J Biol Chem. 1985 Nov 05; 260(25):13685-9. Martens GJ, Civelli O, Herbert E. PMID: 3840481.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    186. Sequence and expression of the rat prodynorphin gene. Proc Natl Acad Sci U S A. 1985 Jun; 82(12):4291-5. Civelli O, Douglass J, Goldstein A, Herbert E. PMID: 3858883; PMCID: PMC397984.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    187. Polyprotein gene expression: generation of diversity of neuroendocrine peptides. Annu Rev Biochem. 1984; 53:665-715. Douglass J, Civelli O, Herbert E. PMID: 6383203.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansAnimalsCells
    188. Regulation of expression of opioid peptide genes. Ann Neurol. 1984; 16 Suppl:S22-30. Douglass JO, Civelli O, Birnberg N, Comb M, Uhler M, Lissitzky JC, Herbert E. PMID: 6095739.
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    189. Regulation of opioid gene expression. Peptides. 1983 Sep-Oct; 4(5):651-6. Civelli O, Birnberg N, Comb M, Douglass J, Lissitzky JC, Uhler M, Herbert E. PMID: 6318201.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    190. Messenger RNA for the 73,000-dalton poly(A)-binding protein occurs as translationally repressed mRNP in duck reticulocytes. J Biol Chem. 1983 Feb 10; 258(3):1387-90. Maundrell K, Imaizumi-Scherrer MT, Maxwell ES, Civelli O, Scherrer K. PMID: 6822518.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    191. Transcriptional and post-transcriptional regulation in duck erythroblasts. Dev Biol. 1982 Sep; 93(1):126-38. Imaizumi-Scherrer MT, Maundrell K, Civelli O, Scherrer K. PMID: 6127272.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    192. Detection and quantitation of pro-opiomelanocortin mRNA in pituitary and brain tissues from different species. J Biol Chem. 1982 Jun 25; 257(12):6783-7. Civelli O, Birnberg N, Herbert E. PMID: 6177687.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    193. Regulation of genetic expression of pro-opiomelanocortin in pituitary and extrapituitary tissues of mouse and rat. Adv Biochem Psychopharmacol. 1982; 33:9-18. Herbert E, Birnberg N, Civelli O, Lissitzky JC, Uhler M, Durrin L. PMID: 6181666.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    194. Potential role of mRNP proteins in cytoplasmic control of gene expression in duck erythroblasts. Mol Biol Rep. 1981 May 22; 7(1-3):71-81. Vincent A, Goldenberg S, Standart N, Civelli O, Imaizumi-Scherrer T, Maundrell K, Scherrer K. PMID: 6114396.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    195. Identification and characterization of the translationally repressed cytoplasmic globin messenger-ribonucleoprotein particles from duck erythroblasts. Eur J Biochem. 1980 Dec; 112(3):617-33. Vincent A, Civelli O, Maundrell K, Scherrer K. PMID: 7460940.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    196. Messenger RNA for cataractous lens proteins are also present on normal lens polyribosomes. Eur J Biochem. 1980 Oct; 111(2):593-601. Weill JC, Leca G, Vincent A, Civelli O, Pouliquen Y. PMID: 6161809.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    197. The translational repression of globin mRNA in free cytoplasmic ribonucleoprotein complexes. Eur J Biochem. 1980 Jun; 107(2):577-85. Civelli O, Vincent A, Maundrell K, Buri JF, Scherrer K. PMID: 7398654.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    198. Messenger ribonucleoprotein complexes in avian erythroblasts: carriers of post-transcriptional regulation? Mol Biol Rep. 1979 May 31; 5(1-2):43-51. Maundrell K, Maxwell ES, Civelli O, Vincent A, Goldenberg S, Buri JF, Imaizumi-Scherrer MT, Scherrer K. PMID: 379594.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    199. Synthesis of albumin and malic enzyme in wheat-germ lysates and Xenopus laevis oocytes programmed with chicken-liver messenger RNA. Eur J Biochem. 1979 May 02; 96(1):1-8. Goodridge A, Civelli O, Yip C, Scherrer K. PMID: 456360.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    200. Correlation of specific coding sequences with specific proteins associated in untranslated cytoplasmic messenger ribonucleoprotein complexes of duck erythroblasts. FEBS Lett. 1977 May 15; 77(2):281-6. Vincent A, Civelli O, Buri JF, Scherrer K. PMID: 862930.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    201. Correlation of specific coding sequences with specific proteins associated in untranslated cytoplasmic messenger ribonucleoprotein complexes of duck er. FEBS Lett. 1977 May 15; 77(2):281-286. Vincent A, Civelli O, Buri JF, Scherrer K. PMID: 29667196.
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    202. Evidence for a translational inhibitor linked to globin mRNA in untranslated free cytoplasmic messenger ribonucleoprotein complexes. FEBS Lett. 1976 Dec 15; 72(1):71-6. Civelli O, Vincent A, Buri JF, Scherrer K. PMID: 1001473.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
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