Orkide Koyuncu

Title(s)	Assistant Professor, Microbiology and Molecular Genetics
School	School of Medicine
Address	1001 Health Sciences Road Irvine CA 92697-3950
Phone	(949) 824-0675
vCard	Download vCard

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Neuronal expression of herpes simplex virus-1 VP16 protein induces pseudorabies virus escape from silencing and reactivation. J Virol. 2024 Jul 23; 98(7):e0056124. Hsu Z-S, Engel EA, Enquist LW, Koyuncu OO. PMID: 38869285; PMCID: PMC11264692.

View in: PubMed Mentions: Fields:
Vir Virology
Translation:Animals Cells
New rabies viral resources for multi-scale neural circuit mapping. Mol Psychiatry. 2024 Jul; 29(7):1951-1967. Bouin A, Wu G, Koyuncu OO, Ye Q, Kim KY, Wu MY, Tong L, Chen L, Phan S, Mackey MR, Ramachandra R, Ellisman MH, Holmes TC, Semler BL, Xu X. PMID: 38355784; PMCID: PMC11322437.

View in: PubMed Mentions: 2 Fields:
Mol Molecular Biology Psy Psychiatry
Translation:Humans Animals Cells
Cell Intrinsic Determinants of Alpha Herpesvirus Latency and Pathogenesis in the Nervous System. Viruses. 2023 11 22; 15(12). Salazar S, Luong KTY, Koyuncu OO. PMID: 38140525; PMCID: PMC10747186.

View in: PubMed Mentions: 3 Fields:
Vir Virology
Translation:Humans Cells
Interferon-λ Activates a Differential Response in Peripheral Neurons That Is Effective against Alpha Herpesvirus Infections. Pathogens. 2023 Sep 07; 12(9). Salazar S, Luong KTY, Nua T, Koyuncu OO. PMID: 37764950; PMCID: PMC10536099.

View in: PubMed Mentions: 4
Pseudorabies virus hijacks DDX3X, initiating an addictive "mad itch" and immune suppression, to facilitate viral spread. bioRxiv. 2023 May 09. Cronin SJF, Tejada MA, Song R, Laval K, Cikes D, Ji M, Brai A, Stadlmann J, Novatchikova M, Perlot T, Ali OH, Botta L, Decker T, Lazovic J, Hagelkruys A, Enquist L, Rao S, Koyuncu OO, Penninger JM. PMID: 37214906; PMCID: PMC10197578.

View in: PubMed Mentions:
A Pseudorabies Virus Serine/Threonine Kinase, US3, Promotes Retrograde Transport in Axons via Akt/mToRC1. J Virol. 2022 03 09; 96(5):e0175221. Esteves AD, Koyuncu OO, Enquist LW. PMID: 34985995; PMCID: PMC8906396.

View in: PubMed Mentions: 10 Fields:
Vir Virology
Translation:Animals Cells
CRISPR/Cas9-Constructed Pseudorabies Virus Mutants Reveal the Importance of UL13 in Alphaherpesvirus Escape from Genome Silencing. J Virol. 2021 02 24; 95(6). Van Cleemput J, Koyuncu OO, Laval K, Engel EA, Enquist LW. PMID: 33361431; PMCID: PMC8094956.

View in: PubMed Mentions: 13 Fields:
Vir Virology
Translation:Animals Cells
Identification of African Elephant Polyomavirus in wild elephants and the creation of a vector expressing its viral tumor antigens to transform elephant primary cells. PLoS One. 2021; 16(2):e0244334. Pearson VR, Bosse JB, Koyuncu OO, Scherer J, Toruno C, Robinson R, Abegglen LM, Schiffman JD, Enquist LW, Rall GF. PMID: 33544724; PMCID: PMC7864673.

View in: PubMed Mentions: 2 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
Invasion of the Nervous System. Curr Issues Mol Biol. 2021; 41:1-62. Koyuncu OO, Enquist LW, Engel EA. PMID: 32723924.

View in: PubMed Mentions: 6 Fields:
Mol Molecular Biology
Translation:Humans Animals Cells
Pseudorabies Virus Infection Accelerates Degradation of the Kinesin-3 Motor KIF1A. J Virol. 2020 04 16; 94(9). Huang H, Koyuncu OO, Enquist LW. PMID: 32075931; PMCID: PMC7163149.

View in: PubMed Mentions: 10 Fields:
Vir Virology
Translation:Humans Animals Cells
Virulent Pseudorabies Virus Infection Induces a Specific and Lethal Systemic Inflammatory Response in Mice. J Virol. 2018 12 15; 92(24). Laval K, Vernejoul JB, Van Cleemput J, Koyuncu OO, Enquist LW. PMID: 30258005; PMCID: PMC6258956.

View in: PubMed Mentions: 39 Fields:
Vir Virology
Translation:Animals Cells
Retrograde axonal transport of rabies virus is unaffected by interferon treatment but blocked by emetine locally in axons. PLoS Pathog. 2018 07; 14(7):e1007188. MacGibeny MA, Koyuncu OO, Wirblich C, Schnell MJ, Enquist LW. PMID: 30028873; PMCID: PMC6070286.

View in: PubMed Mentions: 26 Fields:
Mic Microbiology
Translation:Animals Cells
Latent versus productive infection: the alpha herpesvirus switch. Future Virol. 2018 May; 13(6):431-443. Koyuncu OO, MacGibeny MA, Enquist LW. PMID: 29967651; PMCID: PMC6021814.

View in: PubMed Mentions: 23
Compartmented neuronal cultures reveal two distinct mechanisms for alpha herpesvirus escape from genome silencing. PLoS Pathog. 2017 Oct; 13(10):e1006608. Koyuncu OO, MacGibeny MA, Hogue IB, Enquist LW. PMID: 29073268; PMCID: PMC5658187.

View in: PubMed Mentions: 25 Fields:
Mic Microbiology
Translation:Animals Cells
Two Modes of the Axonal Interferon Response Limit Alphaherpesvirus Neuroinvasion. mBio. 2016 Feb 02; 7(1):e02145-15. Song R, Koyuncu OO, Greco TM, Diner BA, Cristea IM, Enquist LW. PMID: 26838720; PMCID: PMC4742712.

View in: PubMed Mentions: 49 Fields:
Mic Microbiology
Translation:Animals Cells
Investigating the biology of alpha herpesviruses with MS-based proteomics. Proteomics. 2015 Jun; 15(12):1943-56. Engel EA, Song R, Koyuncu OO, Enquist LW. PMID: 25764121; PMCID: PMC4482226.

View in: PubMed Mentions: 23 Fields:
Bio Biochemistry
Translation:Animals Cells
The number of alphaherpesvirus particles infecting axons and the axonal protein repertoire determines the outcome of neuronal infection. mBio. 2015 Mar 24; 6(2). Koyuncu OO, Song R, Greco TM, Cristea IM, Enquist LW. PMID: 25805728; PMCID: PMC4453538.

View in: PubMed Mentions: 27 Fields:
Mic Microbiology
Translation:Animals Cells
Virus infections in the nervous system. Cell Host Microbe. 2013 Apr 17; 13(4):379-93. Koyuncu OO, Hogue IB, Enquist LW. PMID: 23601101; PMCID: PMC3647473.

View in: PubMed Mentions: 316 Fields:
Mic Microbiology
Translation:Humans Animals Cells
Efficient retrograde transport of pseudorabies virus within neurons requires local protein synthesis in axons. Cell Host Microbe. 2013 Jan 16; 13(1):54-66. Koyuncu OO, Perlman DH, Enquist LW. PMID: 23332155; PMCID: PMC3552305.

View in: PubMed Mentions: 46 Fields:
Mic Microbiology
Translation:Animals Cells
Amino acid exchanges in the putative nuclear export signal of adenovirus type 5 L4-100K severely reduce viral progeny due to effects on hexon biogenesis. J Virol. 2013 Feb; 87(3):1893-8. Koyuncu OO, Speiseder T, Dobner T, Schmid M. PMID: 23175361; PMCID: PMC3554178.

View in: PubMed Mentions: 4 Fields:
Vir Virology
Translation:Cells
Subversion of the actin cytoskeleton during viral infection. Nat Rev Microbiol. 2011 Jun; 9(6):427-39. Taylor MP, Koyuncu OO, Enquist LW. PMID: 21522191; PMCID: PMC3229036.

View in: PubMed Mentions: 213 Fields:
Mic Microbiology
Translation:Humans Animals Cells
Arginine methylation of human adenovirus type 5 L4 100-kilodalton protein is required for efficient virus production. J Virol. 2009 May; 83(10):4778-90. Koyuncu OO, Dobner T. PMID: 19264777; PMCID: PMC2682095.

View in: PubMed Mentions: 16 Fields:
Vir Virology
Translation:Humans Cells