Mark J Fisher

Title(s)Professor, Neurology
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-6856
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    Collapse Research 
    Collapse Research Activities and Funding
    Hypertensive Mechanisms of Cerebral Microbleeds
    NIH R21NS111984Jun 1, 2019 - May 31, 2021
    Role: Principal Investigator
    MECHANISMS OF ISCHEMIC STROKE
    NIH P01NS031945Jul 1, 1994 - Oct 31, 1999
    Role: Principal Investigator
    Hemorheological Factors in Cerebral Ischemia
    NIH R01NS020989Jul 1, 1984 - Apr 30, 2023
    Role: Principal Investigator
    HEMORHEOLOGICAL ASPECTS OF CEREBRAL VASCULAR DISEASE
    NIH K07NS000884Jul 1, 1984 - Jun 30, 1989
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Vascular Neurology Considerations for Antiamyloid Immunotherapy: A Science Advisory From the American Heart Association. Stroke. 2025 Jan; 56(1):e30-e38. Greenberg SM, Aparicio HJ, Furie KL, Goyal MS, Hinman JD, Kozberg M, Leonard A, Fisher MJ, American Heart Association Stroke Council; Council on Cardiovascular and Stroke Nursing; and Council. PMID: 39660440.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. New Directions in Infection-Associated Ischemic Stroke. J Clin Neurol. 2024 Mar; 20(2):140-152. Jung JM, Gruber A, Heseltine P, Rajamani K, Ameriso SF, Fisher MJ. PMID: 38330416; PMCID: PMC10921058.
      View in: PubMed   Mentions: 1  
    3. Erythrocyte-brain endothelial interactions induce microglial responses and cerebral microhemorrhages in vivo. J Neuroinflammation. 2023 Nov 15; 20(1):265. Zhang H, Sumbria RK, Chang R, Sun J, Cribbs DH, Holmes TC, Fisher MJ, Xu X. PMID: 37968737; PMCID: PMC10647121.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    4. Changes in beat-to-beat blood pressure and pulse rate variability following stroke. Sci Rep. 2023 11 07; 13(1):19245. Abiri A, Chou EF, Shen W, Fisher MJ, Khine M. PMID: 37935766; PMCID: PMC10630489.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. The 2022 FASEB Virtual Catalyst Conference on the Cardiac Interatrial Septum and Stroke Risk, December 7, 2022. FASEB J. 2023 09; 37(9):e23122. Schilling J, Lin JP, Mankad SV, Krishnam MS, Ning M, Patel PM, Kim CK, Kapoor R, Di Tullio MR, Jung J, Kim JK, Fisher MJ. PMID: 37606555.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Comparative studies between the murine immortalized brain endothelial cell line (bEnd.3) and induced pluripotent stem cell-derived human brain endothelial cells for paracellular transport. PLoS One. 2022; 17(5):e0268860. Sun J, Ou W, Han D, Paganini-Hill A, Fisher MJ, Sumbria RK. PMID: 35613139; PMCID: PMC9132315.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    7. Insights Into the Mechanisms of Brain Endothelial Erythrophagocytosis. Front Cell Dev Biol. 2021; 9:672009. Sun J, Vyas P, Mann S, Paganini-Hill A, Nunes ACF, Lau WL, Cribbs DH, Fisher MJ, Sumbria RK. PMID: 34409026; PMCID: PMC8365766.
      View in: PubMed   Mentions: 5  
    8. Reader Response: Association of Ventricular Arrhythmias With Dementia: The Atherosclerosis Risk in Communities (ARIC) Study. Neurology. 2021 07 13; 97(2):99-100. Fisher MJ, Ameriso SF. PMID: 34253652.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Reader Response: White Matter Hyperintensities Mediate the Association of Nocturnal Blood Pressure With Cognition. Neurology. 2021 07 06; 97(1):44-45. Fisher MJ, Paganini-Hill A, Kawas CH, Corrada MM, Fletcher E. PMID: 34226284.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Simple methodology to visualize whole-brain microvasculature in three dimensions. Neurophotonics. 2021 Apr; 8(2):025004. Khouri K, Xie DF, Crouzet C, Bahani AW, Cribbs DH, Fisher MJ, Choi B. PMID: 33884280; PMCID: PMC8056070.
      View in: PubMed   Mentions: 5  
    11. Cerebral Blood Flow in Chronic Kidney Disease. J Stroke Cerebrovasc Dis. 2021 Sep; 30(9):105702. Choi B, Crouzet C, Lau WL, Cribbs DH, Fisher MJ. PMID: 33714675; PMCID: PMC8384649.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    12. Mechanisms of Cerebral Microbleeds. J Neuropathol Exp Neurol. 2020 10 01; 42(2):1093-1099. Wadi LC, Grigoryan MM, Kim RC, Fang C, Kim J, Corrada MM, Paganini-Hill A, Fisher MJ. PMID: 32930790; PMCID: PMC7580489.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    13. The Medial Pontine Mid-Tegmentum Syndrome. J Stroke Cerebrovasc Dis. 2020 Jun; 29(6):104750. Wadi LC, Kim MJ, Fisher MJ. PMID: 32220556.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Bihemisphere Ischemia Due to a Unilateral Lesion: A Case Report. J Stroke Cerebrovasc Dis. 2020 Apr; 29(4):104590. Wadi LC, Nnodim S, Pack J, Fisher MJ. PMID: 31883780.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. Bilateral Limb-Shaking Transient Ischemic Attacks. J Stroke Cerebrovasc Dis. 2020 Mar; 29(3):104577. Miremadi BB, Tran A, Wadi LC, Suzuki S, Fisher MJ. PMID: 31836357.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Effects of Dabigatran in Mouse Models of Aging and Cerebral Amyloid Angiopathy. Front Neurol. 2019; 10:966. Michael N, Grigoryan MM, Kilday K, Sumbria RK, Vasilevko V, van Ryn J, Cribbs DH, Paganini-Hill A, Fisher MJ. PMID: 31611836; PMCID: PMC6776875.
      View in: PubMed   Mentions: 9  
    17. Blood Pressure Circadian Variation, Cognition and Brain Imaging in 90+ Year-Olds. Front Aging Neurosci. 2019; 11:54. Paganini-Hill A, Bryant N, Corrada MM, Greenia DE, Fletcher E, Singh B, Floriolli D, Kawas CH, Fisher MJ. PMID: 31057391; PMCID: PMC6478755.
      View in: PubMed   Mentions: 13  
    18. Brain Endothelial Erythrophagocytosis and Hemoglobin Transmigration Across Brain Endothelium: Implications for Pathogenesis of Cerebral Microbleeds. Front Cell Neurosci. 2018; 12:279. Chang R, Castillo J, Zambon AC, Krasieva TB, Fisher MJ, Sumbria RK. PMID: 30237761; PMCID: PMC6135875.
      View in: PubMed   Mentions: 18  
    19. Aging exacerbates development of cerebral microbleeds in a mouse model. J Neuroinflammation. 2018 Mar 06; 15(1):69. Sumbria RK, Grigoryan MM, Vasilevko V, Paganini-Hill A, Kilday K, Kim R, Cribbs DH, Fisher MJ. PMID: 29510725; PMCID: PMC5840821.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    20. Disseminated Microinfarctions with Cerebral Microbleeds. J Stroke Cerebrovasc Dis. 2018 Jun; 27(6):e95-e97. Fisher M, Kapur K, Soo S, Lyou Y, Schreiber SS, Kim MJ. PMID: 29395640; PMCID: PMC5930065.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Effects of phosphodiesterase 3A modulation on murine cerebral microhemorrhages. J Neuroinflammation. 2017 06 05; 14(1):114. Sumbria RK, Vasilevko V, Grigoryan MM, Paganini-Hill A, Kim R, Cribbs DH, Fisher MJ. PMID: 28583195; PMCID: PMC5460510.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    22. A dysfunctional blood-brain barrier and cerebral small vessel disease. Neurology. 2017 01 31; 88(5):420-421. Hainsworth AH, Fisher MJ. PMID: 28031393.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    23. A murine model of inflammation-induced cerebral microbleeds. J Neuroinflammation. 2016 08 30; 13(1):218. Sumbria RK, Grigoryan MM, Vasilevko V, Krasieva TB, Scadeng M, Dvornikova AK, Paganini-Hill A, Kim R, Cribbs DH, Fisher MJ. PMID: 27577728; PMCID: PMC5006574.
      View in: PubMed   Mentions: 46     Fields:    Translation:Animals
    24. Cerebral microbleeds: where are we now? Neurology. 2014 Oct 07; 83(15):1304-5. Fisher M. PMID: 25186856.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    25. Stroke and the law: principles and practice. Stroke. 2014 Oct; 45(10):3141-6. Fisher M, Schneider P. PMID: 25169947.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. Comparative analysis of H&E and Prussian blue staining in a mouse model of cerebral microbleeds. J Histochem Cytochem. 2014 Nov; 62(11):767-73. Liu S, Grigoryan MM, Vasilevko V, Sumbria RK, Paganini-Hill A, Cribbs DH, Fisher MJ. PMID: 25063000; PMCID: PMC6728446.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    27. Executive dysfunction, brain aging, and political leadership. Politics Life Sci. 2014; 33(2):93-102. Fisher M, Franklin DL, Post JM. PMID: 25901887.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Brain regulation of thrombosis and hemostasis: from theory to practice. Stroke. 2013 Nov; 44(11):3275-85. Fisher MJ. PMID: 24085025; PMCID: PMC3954774.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    29. Phosphodiesterase inhibitor modulation of brain microvascular endothelial cell barrier properties. J Neurol Sci. 2012 Sep 15; 320(1-2):45-51. Liu S, Yu C, Yang F, Paganini-Hill A, Fisher MJ. PMID: 22819056; PMCID: PMC3504123.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    30. Stroke. Geometry is destiny for carotid atherosclerotic plaques. Nat Rev Neurol. 2012 Jan 24; 8(3):127-9. Fisher M. PMID: 22270018.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    31. PDE4 regulates tissue plasminogen activator expression of human brain microvascular endothelial cells. Thromb Res. 2012 Jun; 129(6):750-3. Yang F, Liu S, Yu C, Wang SJ, Paganini-Hill A, Fisher MJ. PMID: 22245243; PMCID: PMC3359414.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    32. Tissue plasminogen activator expression and barrier properties of human brain microvascular endothelial cells. Cell Physiol Biochem. 2011; 28(4):631-8. Yang F, Liu S, Wang SJ, Yu C, Paganini-Hill A, Fisher MJ. PMID: 22178875; PMCID: PMC7077105.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    33. Therapeutic modulation of cerebral microhemorrhage in a mouse model of cerebral amyloid angiopathy. Stroke. 2011 Nov; 42(11):3300-3. Fisher M, Vasilevko V, Passos GF, Ventura C, Quiring D, Cribbs DH. PMID: 21903962; PMCID: PMC3221609.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    34. Ancrod and fibrin formation: perspectives on mechanisms of action. Stroke. 2011 Nov; 42(11):3277-80. Liu S, Marder VJ, Levy DE, Wang SJ, Yang F, Paganini-Hill A, Fisher MJ. PMID: 21868728; PMCID: PMC3236789.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    35. Cerebral microbleeds in the elderly: a pathological analysis. Stroke. 2010 Dec; 41(12):2782-5. Fisher M, French S, Ji P, Kim RC. PMID: 21030702; PMCID: PMC3079284.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    36. The challenge of mixed cerebrovascular disease. Ann N Y Acad Sci. 2010 Oct; 1207:18-22. Fisher M. PMID: 20955421; PMCID: PMC4364441.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    37. Pericyte signaling in the neurovascular unit. Stroke. 2009 Mar; 40(3 Suppl):S13-5. Fisher M. PMID: 19064799; PMCID: PMC2724312.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    38. Stroke care delivery before vs after JCAHO stroke center certification. Neurology. 2007 Feb 06; 68(6):469-70. Stradling D, Yu W, Langdorf ML, Tsai F, Kostanian V, Hasso AN, Welbourne SJ, Schooley Y, Fisher MJ, Cramer SC. PMID: 17283326.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    39. Brain endothelial hemostasis regulation by pericytes. J Cereb Blood Flow Metab. 2006 Feb; 26(2):209-17. Kim JA, Tran ND, Li Z, Yang F, Zhou W, Fisher MJ. PMID: 16015279.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    40. Carotid plaque pathology: thrombosis, ulceration, and stroke pathogenesis. Stroke. 2005 Feb; 36(2):253-7. Fisher M, Paganini-Hill A, Martin A, Cosgrove M, Toole JF, Barnett HJ, Norris J. PMID: 15653581.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    41. Minimally oxidized low-density lipoprotein regulates hemostasis factors of brain capillary endothelial cells. J Neurol Sci. 2004 Feb 15; 217(2):135-41. Kim JA, Tran ND, Berliner JA, Fisher MJ. PMID: 14706215.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    42. Astrocyte regulation of human brain capillary endothelial fibrinolysis. Thromb Res. 2003; 112(3):159-65. Kim JA, Tran ND, Wang SJ, Fisher MJ. PMID: 14967413.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    43. Adenoviral-mediated transfer of tissue plasminogen activator gene into brain capillary endothelial cells in vitro. Angiology. 2001 Sep; 52(9):627-34. Kim JA, Hedrick CC, Xie D, Fisher MJ. PMID: 11570662.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    44. Comparison between pressure-volume and dewpoint-hygrometry techniques for determining the water relations characteristics of grass and legume leaves. Oecologia. 1979 Jul; 41(1):77-88. Wilson JR, Fisher MJ, Schulze E-, Dolby GR, Ludlow MM. PMID: 28310361.
      View in: PubMed   Mentions: 20     Fields:    
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