Michelle R Paff

Title(s)Assistant Health Sciences Professor, Neurosurgery
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-6966
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    1. What Is the Philosophy of Neurosurgery? Systematic Review and Defining the Discipline. World Neurosurg. 2024 Mar 15. Dutta RR, Lopez A, Hsu FPK, Paff M. PMID: 38493892.
      View in: PubMed   Mentions:    Fields:    
    2. Awake ripples enhance emotional memory encoding in the human brain. Nat Commun. 2024 Jan 03; 15(1):215. Zhang H, Skelin I, Ma S, Paff M, Mnatsakanyan L, Yassa MA, Knight RT, Lin JJ. PMID: 38172140; PMCID: PMC10764865.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Deep Brain Stimulation as an Emerging Therapy for Cognitive Decline in Alzheimer Disease: Systematic Review of Evidence and Current Targets. World Neurosurg. 2024 Apr; 184:253-266.e2. Picton B, Wong J, Lopez AM, Solomon SS, Andalib S, Brown NJ, Dutta RR, Paff MR, Hsu FP, Oh MY. PMID: 38141755.
      View in: PubMed   Mentions:    Fields:    
    4. Trends and disparities in deep brain stimulation utilization in the United States: a Nationwide Inpatient Sample analysis from 1993 to 2017. Lancet Reg Health Am. 2023 Oct; 26:100599. Sarica C, Conner CR, Yamamoto K, Yang A, Germann J, Lannon MM, Samuel N, Colditz M, Santyr B, Chow CT, Iorio-Morin C, Aguirre-Padilla DH, Lang ST, Vetkas A, Cheyuo C, Loh A, Darmani G, Flouty O, Milano V, Paff M, Hodaie M, Kalia SK, Munhoz RP, Fasano A, Lozano AM. PMID: 37876670; PMCID: PMC10593574.
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    5. Obtaining brain tissue from living patients for psychiatry research: collaboration with patients with epilepsy and neurosurgeons. Lancet Psychiatry. 2023 06; 10(6):381. Paff M, Grieco SF, Xu X. PMID: 37088087.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Schizophrenia and neurosurgery: systematic review and theories. Neurosurg Focus. 2023 02; 54(2):E7. Dutta RR, Picton B, Brown NJ, Yang C, Lee M, Sung H, Lopez AM, Paff M. PMID: 36724524.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    7. A Functional Connectome of Parkinson's Disease Patients Prior to Deep Brain Stimulation: A Tool for Disease-Specific Connectivity Analyses. Front Neurosci. 2022; 16:804125. Loh A, Boutet A, Germann J, Al-Fatly B, Elias GJB, Neudorfer C, Krotz J, Wong EHY, Parmar R, Gramer R, Paff M, Horn A, Chen JJ, Azevedo P, Fasano A, Munhoz RP, Hodaie M, Kalia SK, Kucharczyk W, Lozano AM. PMID: 35812235; PMCID: PMC9263841.
      View in: PubMed   Mentions: 2  
    8. Clinical outcomes and complications of peripheral nerve field stimulation in the management of refractory trigeminal pain: a systematic review and meta-analysis. J Neurosurg. 2022 Feb 18; 1-9. Sarica C, Iorio-Morin C, Aguirre-Padilla DH, Paff M, Villeneuve SA, Vetkas A, Yamamoto K, Samuel N, Milano V, Loh A, Santyr B, Zemmar A, Lozano AM, Hodaie M. PMID: 35180702.
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    9. Consciousness is supported by near-critical slow cortical electrodynamics. Proc Natl Acad Sci U S A. 2022 02 15; 119(7). Toker D, Pappas I, Lendner JD, Frohlich J, Mateos DM, Muthukumaraswamy S, Carhart-Harris R, Paff M, Vespa PM, Monti MM, Sommer FT, Knight RT, D'Esposito M. PMID: 35145021; PMCID: PMC8851554.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    10. Leukoencephalopathy with brain calcifications and cysts (Labrune syndrome) case report: diagnosis and management of a rare neurological disease. BMC Neurol. 2022 Jan 05; 22(1):10. Paff M, Samuel N, Alsafwani N, Paul D, Diamandis P, Climans SA, Kucharczyk W, Ding MYR, Gao AF, Lozano AM. PMID: 34986804; PMCID: PMC8729138.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    11. Mapping autonomic, mood and cognitive effects of hypothalamic region deep brain stimulation. Brain. 2021 10 22; 144(9):2837-2851. Neudorfer C, Elias GJB, Jakobs M, Boutet A, Germann J, Narang K, Loh A, Paff M, Horn A, Kucharczyk W, Deeb W, Salvato B, Almeida L, Foote KD, Rosenberg PB, Tang-Wai DF, Anderson WS, Mari Z, Ponce FA, Wolk DA, Burke AD, Salloway S, Sabbagh MN, Chakravarty MM, Smith GS, Lyketsos CG, Okun MS, Lozano AM. PMID: 33905474; PMCID: PMC8557336.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    12. Neuromodulatory treatments for psychiatric disease: A comprehensive survey of the clinical trial landscape. Brain Stimul. 2021 Sep-Oct; 14(5):1393-1403. Elias GJB, Boutet A, Parmar R, Wong EHY, Germann J, Loh A, Paff M, Pancholi A, Gwun D, Chow CT, Gouveia FV, Harmsen IE, Beyn ME, Santarnecchi E, Fasano A, Blumberger DM, Kennedy SH, Lozano AM, Bhat V. PMID: 34461326.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    13. Implantable Pulse Generators for Deep Brain Stimulation: Challenges, Complications, and Strategies for Practicality and Longevity. Front Hum Neurosci. 2021; 15:708481. Sarica C, Iorio-Morin C, Aguirre-Padilla DH, Najjar A, Paff M, Fomenko A, Yamamoto K, Zemmar A, Lipsman N, Ibrahim GM, Hamani C, Hodaie M, Lozano AM, Munhoz RP, Fasano A, Kalia SK. PMID: 34512295; PMCID: PMC8427803.
      View in: PubMed   Mentions: 11  
    14. Focused Ultrasound Thalamotomy Sensory Side Effects Follow the Thalamic Structural Homunculus. Neurol Clin Pract. 2021 Aug; 11(4):e497-e503. Paff M, Boutet A, Germann J, Elias GJB, Chow CT, Loh A, Kucharczyk W, Fasano A, Schwartz ML, Lozano AM. PMID: 34484947; PMCID: PMC8382439.
      View in: PubMed   Mentions:
    15. Lateralizing magnetic resonance imaging findings in mesial temporal sclerosis and correlation with seizure and neurocognitive outcome after temporal lobectomy. Epilepsy Res. 2021 03; 171:106562. Paff M, Boutet A, Elias GJB, Germann J, Mansouri A, Loh A, Gwun D, Neudorfer C, McAndrews MP, Gold D, Lozano AM, Valiante TA. PMID: 33540156.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Endovascular deep brain stimulation: Investigating the relationship between vascular structures and deep brain stimulation targets. Brain Stimul. 2020 Nov - Dec; 13(6):1668-1677. Neudorfer C, Bhatia K, Boutet A, Germann J, Elias GJ, Loh A, Paff M, Krings T, Lozano AM. PMID: 33035721.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    17. Surgical Robot-Enhanced Implantation of Intracranial Depth Electrodes for Single Neuron Recording Studies in Patients with Medically Refractory Epilepsy: A Technical Note. World Neurosurg. 2021 01; 145:210-219. Urgun K, Paff M, Chan A, Hsu F, Vadera S. PMID: 32980570.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    18. Update on Current Technologies for Deep Brain Stimulation in Parkinson's Disease. J Mov Disord. 2020 Sep; 13(3):185-198. Paff M, Loh A, Sarica C, Lozano AM, Fasano A. PMID: 32854482; PMCID: PMC7502302.
      View in: PubMed   Mentions: 27  
    19. Robotic Orthogonal Implantation of Responsive Neurostimulation (RNS) Depth Electrodes in the Mesial Temporal Lobe: Case Series. Oper Neurosurg (Hagerstown). 2020 07 01; 19(1):19-24. Chan AY, Tran DK, Paff MR, Urgun K, Hsu FPK, Vadera S. PMID: 31792508.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. A Novel Robotic-Assisted Technique to Implant the Responsive Neurostimulation System. Oper Neurosurg (Hagerstown). 2020 06 01; 18(6):728-735. Tran DK, Paff M, Mnatsakanyan L, Sen-Gupta I, Lin JJ, Hsu FPK, Vadera S. PMID: 31538187.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    21. Magnetic Resonance-Guided Focused Ultrasound Thalamotomy to Treat Essential Tremor in Nonagenarians. Stereotact Funct Neurosurg. 2020; 98(3):182-186. Paff M, Boutet A, Neudorfer C, Elias GJB, Germann J, Loh A, Kucharczyk W, Fasano A, Schwartz ML, Lozano AM. PMID: 32224617; PMCID: PMC7384340.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    22. Two-year clinical outcomes associated with robotic-assisted subthalamic lead implantation in patients with Parkinson's disease. J Robot Surg. 2020 Aug; 14(4):559-565. Paff M, Wang AS, Phielipp N, Vadera S, Morenkova A, Hermanowicz N, Hsu FPK. PMID: 31520275.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    23. Bidirectional prefrontal-hippocampal dynamics organize information transfer during sleep in humans. Nat Commun. 2019 08 08; 10(1):3572. Helfrich RF, Lendner JD, Mander BA, Guillen H, Paff M, Mnatsakanyan L, Vadera S, Walker MP, Lin JJ, Knight RT. PMID: 31395890; PMCID: PMC6687745.
      View in: PubMed   Mentions: 66     Fields:    Translation:Humans
    24. Scalp Intravenous Catheter Infiltration Leading to Subdural and Intraparenchymal Fluid Collection and Severe Neurologic Sequelae: A Case Report. Perm J. 2019; 23. Alexandru-Abrams D, Paff M, Loudon WG. PMID: 30939275; PMCID: PMC6443361.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Decreasing the Cerebral Edema Associated with Traumatic Intracerebral Hemorrhages: Use of a Minimally Invasive Technique. Acta Neurochir Suppl. 2016; 121:279-84. Chen JW, Paff MR, Abrams-Alexandru D, Kaloostian SW. PMID: 26463961.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. The evolution of the EGFRvIII (rindopepimut) immunotherapy for glioblastoma multiforme patients. Hum Vaccin Immunother. 2014; 10(11):3322-31. Paff M, Alexandru-Abrams D, Hsu FP, Bota DA. PMID: 25625931; PMCID: PMC4514075.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsPHPublic Health
    27. Artist's statement: the tracheostomy. Acad Med. 2013 May; 88(5):584. Paff M. PMID: 23611972.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Artist's statement: my cadaver. Acad Med. 2009 Jul; 84(7):829. Paff M. PMID: 19550171.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. Border formation in a Bmp gradient reduced to single dissociated cells. Proc Natl Acad Sci U S A. 2008 Mar 04; 105(9):3398-403. Hu JS, Doan LT, Currle DS, Paff M, Rheem JY, Schreyer R, Robert B, Monuki ES. PMID: 18292231; PMCID: PMC2265170.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
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