Andrea J. Tenner

Title(s)Professor, Molecular Biology & Biochemistry
SchoolSchool of Biological Sciences
Address2228 McGaugh Hall
Zot 3900
Irvine CA 92697
Phone(949) 824-3268, 3266
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    Collapse Research 
    Collapse Research Activities and Funding
    Assessing cell specific proteomes in the presence and absence of C5a complement signaling in Alzheimer's disease models
    NIH R21AG068573Aug 1, 2020 - Apr 30, 2022
    Role: Co-Principal Investigator
    Modulating Polarization of Glial Cells in AD mouse models by a Complement Receptor Antagonist
    NIH R21AG061746Feb 1, 2019 - Nov 30, 2021
    Role: Principal Investigator
    Defining the Mechanistic Link between C5aR1 signaling and cognitive loss in Alzheimer's diseases
    NIH R01AG060148Sep 15, 2018 - May 31, 2022
    Role: Principal Investigator
    UC Irvine AD Translational Center for Disease Model Resources
    NIH U54AG054349Sep 15, 2017 - Aug 31, 2022
    Role: Co-Principal Investigator
    Inflammation in Innate and Adaptive Immune Mechanisms
    NIH R13AI102527Sep 1, 2012 - Aug 31, 2013
    Role: Principal Investigator
    Infection, Inflammation, Immunity
    NIH R13AI096809Jun 15, 2011 - May 31, 2012
    Role: Principal Investigator
    Complement and Inflammatory Factors in AD Pathogenesis
    NIH R01NS035144Feb 1, 1997 - Apr 30, 2016
    Role: Principal Investigator
    Interaction of Clq on Phagocytic Cells
    NIH R01AI041090Jul 1, 1996 - Mar 31, 2012
    Role: Principal Investigator
    INTERACTIONS OF C1Q WITH PHAGOCYTIC CELLS
    NIH R01AI027168Feb 1, 1989 - Jan 31, 1993
    Role: Co-Principal Investigator
    Training in the Neurobiology of Aging and Alzheimer's Disease
    NIH T32AG000096Sep 29, 1982 - Apr 30, 2024
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sex-specific associations between AD genotype and the microbiome of human amyloid beta knock-in (hAβ-KI) mice. Alzheimers Dement. 2024 Apr 04. Dunham SJB, Avelar-Barragan J, Rothman JA, Adams ED, Faraci G, Forner S, Kawauchi S, Tenner AJ, Green KN, LaFerla FM, MacGregor GR, Mapstone M, Whiteson KL. PMID: 38572865.
      View in: PubMed   Mentions:    Fields:    
    2. The Abca7V1613M variant reduces Aβ generation, plaque load, and neuronal damage. Alzheimers Dement. 2024 Mar 20. Butler CA, Mendoza Arvilla A, Milinkeviciute G, Da Cunha C, Kawauchi S, Rezaie N, Liang HY, Javonillo D, Thach A, Wang S, Collins S, Walker A, Shi KX, Neumann J, Gomez-Arboledas A, Henningfield CM, Hohsfield LA, Mapstone M, Tenner AJ, LaFerla FM, Mortazavi A, MacGregor GR, Green KN. PMID: 38506634.
      View in: PubMed   Mentions:    Fields:    
    3. BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease. Alzheimers Dement. 2024 Mar 09. Garcia-Agudo LF, Shi Z, Smith IF, Kramár EA, Tran K, Kawauchi S, Wang S, Collins S, Walker A, Shi KX, Neumann J, Liang HY, Da Cunha C, Milinkeviciute G, Morabito S, Miyoshi E, Rezaie N, Gomez-Arboledas A, Arvilla AM, Ghaemi DI, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, Swarup V, MacGregor GR, Green KN. PMID: 38460121.
      View in: PubMed   Mentions:    Fields:    
    4. Genetic diversity promotes resilience in a mouse model of Alzheimer's disease. Alzheimers Dement. 2024 Mar 01. Soni N, Hohsfield LA, Tran KM, Kawauchi S, Walker A, Javonillo D, Phan J, Matheos D, Da Cunha C, Uyar A, Milinkeviciute G, Gomez-Arboledas A, Tran K, Kaczorowski CC, Wood MA, Tenner AJ, LaFerla FM, Carter GW, Mortazavi A, Swarup V, MacGregor GR, Green KN. PMID: 38426371.
      View in: PubMed   Mentions:    Fields:    
    5. C5aR1 signaling promotes region- and age-dependent synaptic pruning in models of Alzheimer's disease. Alzheimers Dement. 2024 Mar; 20(3):2173-2190. Gomez-Arboledas A, Fonseca MI, Kramar E, Chu SH, Schartz ND, Selvan P, Wood MA, Tenner AJ. PMID: 38278523.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. C5aR1 signaling promotes region and age dependent synaptic pruning in models of Alzheimer's Disease. bioRxiv. 2023 Oct 02. Gomez-Arboledas A, Fonseca MI, Kramar E, Chu SH, Schartz N, Selvan P, Wood MA, Tenner AJ. PMID: 37873302; PMCID: PMC10592845.
      View in: PubMed   Mentions:
    7. Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer's mouse models. J Neuroinflammation. 2023 Sep 19; 20(1):211. Petrisko TJ, Gargus M, Chu SH, Selvan P, Whiteson KL, Tenner AJ. PMID: 37726739; PMCID: PMC10507976.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. C5aR1 antagonism suppresses inflammatory glial gene expression and alters cellular signaling in an aggressive Alzheimer's model. bioRxiv. 2023 Aug 22. Schartz ND, Liang HY, Carvalho K, Chu SH, Mendoza-Arvilla A, Petrisko TJ, Gomez-Arboledas A, Mortazavi A, Tenner AJ. PMID: 37662399; PMCID: PMC10473603.
      View in: PubMed   Mentions:
    9. A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques. Mol Neurodegener. 2023 02 17; 18(1):12. Tran KM, Kawauchi S, Kramár EA, Rezaie N, Liang HY, Sakr JS, Gomez-Arboledas A, Arreola MA, Cunha CD, Phan J, Wang S, Collins S, Walker A, Shi KX, Neumann J, Filimban G, Shi Z, Milinkeviciute G, Javonillo DI, Tran K, Gantuz M, Forner S, Swarup V, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, MacGregor GR, Green KN. PMID: 36803190; PMCID: PMC9938579.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    10. Complement in the Brain: Contributions to Neuroprotection, Neuronal Plasticity, and Neuroinflammation. Annu Rev Immunol. 2023 04 26; 41:431-452. Bohlson SS, Tenner AJ. PMID: 36750318.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    11. Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer's disease. Neurobiol Dis. 2023 01; 176:105939. Zhang H, Chen L, Johnston KG, Crapser J, Green KN, Ha NM, Tenner AJ, Holmes TC, Nitz DA, Xu X. PMID: 36462718; PMCID: PMC10187684.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    12. C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer's disease. Acta Neuropathol Commun. 2022 Aug 17; 10(1):116. Gomez-Arboledas A, Carvalho K, Balderrama-Gutierrez G, Chu SH, Liang HY, Schartz ND, Selvan P, Petrisko TJ, Pan MA, Mortazavi A, Tenner AJ. PMID: 35978440; PMCID: PMC9386996.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    13. Modulation of C5a-C5aR1 signaling alters the dynamics of AD progression. J Neuroinflammation. 2022 Jul 11; 19(1):178. Carvalho K, Schartz ND, Balderrama-Gutierrez G, Liang HY, Chu SH, Selvan P, Gomez-Arboledas A, Petrisko TJ, Fonseca MI, Mortazavi A, Tenner AJ. PMID: 35820938; PMCID: PMC9277945.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    14. Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease. Front Neurosci. 2021; 15:785276. Javonillo DI, Tran KM, Phan J, Hingco E, Kramár EA, da Cunha C, Forner S, Kawauchi S, Milinkeviciute G, Gomez-Arboledas A, Neumann J, Banh CE, Huynh M, Matheos DP, Rezaie N, Alcantara JA, Mortazavi A, Wood MA, Tenner AJ, MacGregor GR, Green KN, LaFerla FM. PMID: 35140584; PMCID: PMC8818877.
      View in: PubMed   Mentions: 37  
    15. Complement as a powerful "influencer" in the brain during development, adulthood and neurological disorders. Adv Immunol. 2021; 152:157-222. Petrisko TJ, Gomez-Arboledas A, Tenner AJ. PMID: 34844709.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    16. C1q and SRPX2 regulate microglia mediated synapse elimination during early development in the visual thalamus but not the visual cortex. Glia. 2022 03; 70(3):451-465. Cong Q, Soteros BM, Huo A, Li Y, Tenner AJ, Sia GM. PMID: 34762332; PMCID: PMC8732326.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    17. Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease. Sci Data. 2021 10 15; 8(1):270. Forner S, Kawauchi S, Balderrama-Gutierrez G, Kramár EA, Matheos DP, Phan J, Javonillo DI, Tran KM, Hingco E, da Cunha C, Rezaie N, Alcantara JA, Baglietto-Vargas D, Jansen C, Neumann J, Wood MA, MacGregor GR, Mortazavi A, Tenner AJ, LaFerla FM, Green KN. PMID: 34654824; PMCID: PMC8519958.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    18. The Role of Complement in Synaptic Pruning and Neurodegeneration. Immunotargets Ther. 2021; 10:373-386. Gomez-Arboledas A, Acharya MM, Tenner AJ. PMID: 34595138; PMCID: PMC8478425.
      View in: PubMed   Mentions: 33  
    19. Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology. Nat Commun. 2021 04 23; 12(1):2421. Baglietto-Vargas D, Forner S, Cai L, Martini AC, Trujillo-Estrada L, Swarup V, Nguyen MMT, Do Huynh K, Javonillo DI, Tran KM, Phan J, Jiang S, Kramár EA, Nuñez-Diaz C, Balderrama-Gutierrez G, Garcia F, Childs J, Rodriguez-Ortiz CJ, Garcia-Leon JA, Kitazawa M, Shahnawaz M, Matheos DP, Ma X, Da Cunha C, Walls KC, Ager RR, Soto C, Gutierrez A, Moreno-Gonzalez I, Mortazavi A, Tenner AJ, MacGregor GR, Wood M, Green KN, LaFerla FM. PMID: 33893290; PMCID: PMC8065162.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    20. Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics. Pharmacol Rev. 2021 04; 73(2):792-827. Garred P, Tenner AJ, Mollnes TE. PMID: 33687995; PMCID: PMC7956994.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCellsPHPublic Health
    21. The good, the bad, and the opportunities of the complement system in neurodegenerative disease. J Neuroinflammation. 2020 Nov 25; 17(1):354. Schartz ND, Tenner AJ. PMID: 33239010; PMCID: PMC7690210.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimals
    22. Complement-Mediated Events in Alzheimer's Disease: Mechanisms and Potential Therapeutic Targets. J Immunol. 2020 01 15; 204(2):306-315. Tenner AJ. PMID: 31907273; PMCID: PMC6951444.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    23. Complement Nomenclature-Deconvoluted. Front Immunol. 2019; 10:1308. Bohlson SS, Garred P, Kemper C, Tenner AJ. PMID: 31231398; PMCID: PMC6568193.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    24. Preface to the Special issue for the 27th International complement workshop. Mol Immunol. 2018 10; 102:1-2. Tenner AJ, Atkinson JP, Holers VM. PMID: 30060927.
      View in: PubMed   Mentions:    Fields:    
    25. New tricks for an ancient system: Physiological and pathological roles of complement in the CNS. Mol Immunol. 2018 10; 102:3-13. Tenner AJ, Stevens B, Woodruff TM. PMID: 29958698; PMCID: PMC6478444.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimals
    26. Peripheral complement interactions with amyloid β peptide in Alzheimer's disease: Polymorphisms, structure, and function of complement receptor 1. Alzheimers Dement. 2018 11; 14(11):1438-1449. Johansson JU, Brubaker WD, Javitz H, Bergen AW, Nishita D, Trigunaite A, Crane A, Ceballos J, Mastroeni D, Tenner AJ, Sabbagh M, Rogers J. PMID: 29792870; PMCID: PMC6231989.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    27. Incorporation of a Ligand Peptide for Immune Inhibitory Receptor LAIR-1 on Biomaterial Surfaces Inhibits Macrophage Inflammatory Responses. Adv Healthc Mater. 2017 Dec; 6(24). Kim YK, Chu SH, Hsieh JY, Kamoku CM, Tenner AJ, Liu WF, Wang SW. PMID: 29083540; PMCID: PMC5792650.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    28. Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss. Mol Neurodegener. 2017 09 18; 12(1):66. Hernandez MX, Jiang S, Cole TA, Chu SH, Fonseca MI, Fang MJ, Hohsfield LA, Torres MD, Green KN, Wetsel RA, Mortazavi A, Tenner AJ. PMID: 28923083; PMCID: PMC5604420.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    29. Peripheral complement interactions with amyloid β peptide in Alzheimer's disease: 2. Relationship to amyloid β immunotherapy. Alzheimers Dement. 2018 02; 14(2):243-252. Crane A, Brubaker WD, Johansson JU, Trigunaite A, Ceballos J, Bradt B, Glavis-Bloom C, Wallace TL, Tenner AJ, Rogers J. PMID: 28755839; PMCID: PMC5881571.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    30. C1q: A fresh look upon an old molecule. Mol Immunol. 2017 09; 89:73-83. Thielens NM, Tedesco F, Bohlson SS, Gaboriaud C, Tenner AJ. PMID: 28601358; PMCID: PMC5582005.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCells
    31. Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain. J Neuroinflammation. 2017 03 06; 14(1):48. Fonseca MI, Chu SH, Hernandez MX, Fang MJ, Modarresi L, Selvan P, MacGregor GR, Tenner AJ. PMID: 28264694; PMCID: PMC5340039.
      View in: PubMed   Mentions: 155     Fields:    Translation:AnimalsCells
    32. C5a Increases the Injury to Primary Neurons Elicited by Fibrillar Amyloid Beta. ASN Neuro. 2017 Feb; 9(1):1759091416687871. Hernandez MX, Namiranian P, Nguyen E, Fonseca MI, Tenner AJ. PMID: 28078911; PMCID: PMC5298486.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    33. Preface to the Special Issue for the XXVI International Complement Workshop. Immunobiology. 2016 10; 221(10):1035-6. Fujita T, Wakamiya N, Tenner AJ. PMID: 27402136.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    34. Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function. PLoS One. 2016; 11(2):e0149792. Fonseca MI, Chu S, Pierce AL, Brubaker WD, Hauhart RE, Mastroeni D, Clarke EV, Rogers J, Atkinson JP, Tenner AJ. PMID: 26914463; PMCID: PMC4767815.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    35. Sialylation of neurites inhibits complement-mediated macrophage removal in a human macrophage-neuron Co-Culture System. Glia. 2016 Jan; 64(1):35-47. Linnartz-Gerlach B, Schuy C, Shahraz A, Tenner AJ, Neumann H. PMID: 26257016; PMCID: PMC4715670.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    36. Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus. J Neurosci. 2015 Jul 08; 35(27):9977-89. Rice RA, Spangenberg EE, Yamate-Morgan H, Lee RJ, Arora RP, Hernandez MX, Tenner AJ, West BL, Green KN. PMID: 26156998; PMCID: PMC4495246.
      View in: PubMed   Mentions: 131     Fields:    Translation:AnimalsCells
    37. A Commentary On: "NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer's Disease". A cautionary note regarding C3aR. Front Immunol. 2015; 6:220. Woodruff TM, Tenner AJ. PMID: 25999955; PMCID: PMC4423305.
      View in: PubMed   Mentions: 10     Fields:    
    38. Complement protein C1q bound to apoptotic cells suppresses human macrophage and dendritic cell-mediated Th17 and Th1 T cell subset proliferation. J Leukoc Biol. 2015 Jan; 97(1):147-60. Clarke EV, Weist BM, Walsh CM, Tenner AJ. PMID: 25381385; PMCID: PMC4377823.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    39. Complement modulation of T cell immune responses during homeostasis and disease. J Leukoc Biol. 2014 Nov; 96(5):745-56. Clarke EV, Tenner AJ. PMID: 25210145; PMCID: PMC4197570.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    40. Purification of Human Monocytes and Lymphocyte Populations by Counter Current Elutriation- A Short Protocol. Bio Protoc. 2013 Dec 05; 3(23). Clarke EV, Benoit ME, Tenner AJ. PMID: 27081666; PMCID: PMC4828965.
      View in: PubMed   Mentions: 1  
    41. Real-time imaging of Toxoplasma-infected human monocytes under fluidic shear stress reveals rapid translocation of intracellular parasites across endothelial barriers. Cell Microbiol. 2014 Apr; 16(4):580-95. Ueno N, Harker KS, Clarke EV, McWhorter FY, Liu WF, Tenner AJ, Lodoen MB. PMID: 24245749; PMCID: PMC4141879.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    42. C1q Binding to and Uptake of Apoptotic Lymphocytes by Human Monocyte-derived Macrophages. Bio Protoc. 2013 Sep 05; 3(17). Benoit ME, Clarke EV, Tenner AJ. PMID: 27064237; PMCID: PMC4822710.
      View in: PubMed   Mentions:
    43. Complement activation fragment C5a receptors, CD88 and C5L2, are associated with neurofibrillary pathology. J Neuroinflammation. 2013 Feb 08; 10:25. Fonseca MI, McGuire SO, Counts SE, Tenner AJ. PMID: 23394121; PMCID: PMC3605123.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    44. C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid-β neurotoxicity. J Biol Chem. 2013 Jan 04; 288(1):654-65. Benoit ME, Hernandez MX, Dinh ML, Benavente F, Vasquez O, Tenner AJ. PMID: 23150673; PMCID: PMC3537064.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    45. Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study. J Neuroinflammation. 2012 Jul 23; 9:179. Cribbs DH, Berchtold NC, Perreau V, Coleman PD, Rogers J, Tenner AJ, Cotman CW. PMID: 22824372; PMCID: PMC3419089.
      View in: PubMed   Mentions: 249     Fields:    Translation:HumansCells
    46. Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells. J Immunol. 2012 Jun 01; 188(11):5682-93. Benoit ME, Clarke EV, Morgado P, Fraser DA, Tenner AJ. PMID: 22523386; PMCID: PMC3358549.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansCells
    47. Sialic acid on the neuronal glycocalyx prevents complement C1 binding and complement receptor-3-mediated removal by microglia. J Neurosci. 2012 Jan 18; 32(3):946-52. Linnartz B, Kopatz J, Tenner AJ, Neumann H. PMID: 22262892; PMCID: PMC4037907.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    48. Complement in the brain. Mol Immunol. 2011 Aug; 48(14):1592-603. Veerhuis R, Nielsen HM, Tenner AJ. PMID: 21546088; PMCID: PMC3142281.
      View in: PubMed   Mentions: 206     Fields:    Translation:HumansAnimalsCells
    49. Complement protein C1q-mediated neuroprotection is correlated with regulation of neuronal gene and microRNA expression. J Neurosci. 2011 Mar 02; 31(9):3459-69. Benoit ME, Tenner AJ. PMID: 21368058; PMCID: PMC3080046.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    50. Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease. J Neuroinflammation. 2011 Jan 15; 8(1):4. Fonseca MI, Chu SH, Berci AM, Benoit ME, Peters DG, Kimura Y, Tenner AJ. PMID: 21235806; PMCID: PMC3033336.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimals
    51. Innate immune proteins C1q and mannan-binding lectin enhance clearance of atherogenic lipoproteins by human monocytes and macrophages. J Immunol. 2010 Oct 01; 185(7):3932-9. Fraser DA, Tenner AJ. PMID: 20833838; PMCID: PMC3334294.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    52. A novel CD93 polymorphism in non-obese diabetic (NOD) and NZB/W F1 mice is linked to a CD4+ iNKT cell deficient state. Immunogenetics. 2010 Jun; 62(6):397-407. Zekavat G, Mozaffari R, Arias VJ, Rostami SY, Badkerhanian A, Tenner AJ, Nichols KE, Naji A, Noorchashm H. PMID: 20387063; PMCID: PMC2875467.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    53. Microglial C5aR (CD88) expression correlates with amyloid-beta deposition in murine models of Alzheimer's disease. J Neurochem. 2010 Apr; 113(2):389-401. Ager RR, Fonseca MI, Chu SH, Sanderson SD, Taylor SM, Woodruff TM, Tenner AJ. PMID: 20132482; PMCID: PMC2921960.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    54. C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production. J Neurochem. 2010 Feb; 112(3):733-43. Fraser DA, Pisalyaput K, Tenner AJ. PMID: 19919576; PMCID: PMC2809134.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    55. C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells. J Immunol. 2009 Nov 15; 183(10):6175-85. Fraser DA, Laust AK, Nelson EL, Tenner AJ. PMID: 19864605; PMCID: PMC2843563.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    56. The role of the complement system and the activation fragment C5a in the central nervous system. Neuromolecular Med. 2010 Jun; 12(2):179-92. Woodruff TM, Ager RR, Tenner AJ, Noakes PG, Taylor SM. PMID: 19763906.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    57. Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. J Immunol. 2009 Jul 15; 183(2):1375-83. Fonseca MI, Ager RR, Chu SH, Yazan O, Sanderson SD, LaFerla FM, Taylor SM, Woodruff TM, Tenner AJ. PMID: 19561098; PMCID: PMC4067320.
      View in: PubMed   Mentions: 142     Fields:    Translation:AnimalsCells
    58. The role of the anaphylatoxins in health and disease. Mol Immunol. 2009 Sep; 46(14):2753-66. Klos A, Tenner AJ, Johswich KO, Ager RR, Reis ES, Köhl J. PMID: 19477527; PMCID: PMC2725201.
      View in: PubMed   Mentions: 305     Fields:    Translation:HumansAnimalsCells
    59. The complement cascade: Yin-Yang in neuroinflammation--neuro-protection and -degeneration. J Neurochem. 2008 Dec; 107(5):1169-87. Alexander JJ, Anderson AJ, Barnum SR, Stevens B, Tenner AJ. PMID: 18786171; PMCID: PMC4038542.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    60. Complement C3 and C4 expression in C1q sufficient and deficient mouse models of Alzheimer's disease. J Neurochem. 2008 Sep; 106(5):2080-92. Zhou J, Fonseca MI, Pisalyaput K, Tenner AJ. PMID: 18624920; PMCID: PMC2574638.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    61. Murine low-density lipoprotein receptor-related protein 1 (LRP) is required for phagocytosis of targets bearing LRP ligands but is not required for C1q-triggered enhancement of phagocytosis. J Immunol. 2008 Jul 01; 181(1):364-73. Lillis AP, Greenlee MC, Mikhailenko I, Pizzo SV, Tenner AJ, Strickland DK, Bohlson SS. PMID: 18566402; PMCID: PMC2663906.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    62. Development of a humanized C1q A chain knock-in mouse: assessment of antibody independent beta-amyloid induced complement activation. Mol Immunol. 2008 Jun; 45(11):3244-52. Li M, Ager RR, Fraser DA, Tjokro NO, Tenner AJ. PMID: 18400300; PMCID: PMC2453780.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    63. Directing an appropriate immune response: the role of defense collagens and other soluble pattern recognition molecules. Curr Drug Targets. 2008 Feb; 9(2):113-22. Fraser DA, Tenner AJ. PMID: 18288962.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    64. Complement component C1q inhibits beta-amyloid- and serum amyloid P-induced neurotoxicity via caspase- and calpain-independent mechanisms. J Neurochem. 2008 Feb; 104(3):696-707. Pisalyaput K, Tenner AJ. PMID: 17986223.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    65. Generation of inhibitory NFkappaB complexes and phosphorylated cAMP response element-binding protein correlates with the anti-inflammatory activity of complement protein C1q in human monocytes. J Biol Chem. 2007 Mar 09; 282(10):7360-7. Fraser DA, Arora M, Bohlson SS, Lozano E, Tenner AJ. PMID: 17209050.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    66. Complement proteins C1q and MBL are pattern recognition molecules that signal immediate and long-term protective immune functions. Mol Immunol. 2007 Jan; 44(1-3):33-43. Bohlson SS, Fraser DA, Tenner AJ. PMID: 16908067.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    67. C1q and MBL, components of the innate immune system, influence monocyte cytokine expression. J Leukoc Biol. 2006 Jul; 80(1):107-16. Fraser DA, Bohlson SS, Jasinskiene N, Rawal N, Palmarini G, Ruiz S, Rochford R, Tenner AJ. PMID: 16617157.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    68. The double-edged flower: roles of complement protein C1q in neurodegenerative diseases. Adv Exp Med Biol. 2006; 586:153-76. Tenner AJ, Fonseca MI. PMID: 16893071.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    69. Novel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease. J Neuroinflammation. 2005 Dec 07; 2:28. Zhou J, Fonseca MI, Kayed R, Hernandez I, Webster SD, Yazan O, Cribbs DH, Glabe CG, Tenner AJ. PMID: 16332263; PMCID: PMC1326209.
      View in: PubMed   Mentions: 23     Fields:    
    70. Complement in BuB/BnJ mice revisited: serum C3 levels and complement opsonic activity are not elevated. Mol Immunol. 2006 Apr; 43(10):1722-5. Osmers I, Szalai AJ, Tenner AJ, Barnum SR. PMID: 16310250.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    71. CD93 is rapidly shed from the surface of human myeloid cells and the soluble form is detected in human plasma. J Immunol. 2005 Jul 15; 175(2):1239-47. Bohlson SS, Silva R, Fonseca MI, Tenner AJ. PMID: 16002728.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    72. Modulated interaction of the ERM protein, moesin, with CD93. Immunology. 2005 May; 115(1):63-73. Zhang M, Bohlson SS, Dy M, Tenner AJ. PMID: 15819698; PMCID: PMC1782122.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    73. Differential regulation of Abeta42-induced neuronal C1q synthesis and microglial activation. J Neuroinflammation. 2005 Jan 10; 2(1):1. Fan R, Tenner AJ. PMID: 15642121; PMCID: PMC545941.
      View in: PubMed   Mentions: 6     Fields:    
    74. Macrophage colony stimulatory factor and interferon-gamma trigger distinct mechanisms for augmentation of beta-amyloid-induced microglia-mediated neurotoxicity. J Neurochem. 2004 Nov; 91(3):623-33. Li M, Pisalyaput K, Galvan M, Tenner AJ. PMID: 15485493.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    75. CD93 interacts with the PDZ domain-containing adaptor protein GIPC: implications in the modulation of phagocytosis. J Leukoc Biol. 2005 Jan; 77(1):80-9. Bohlson SS, Zhang M, Ortiz CE, Tenner AJ. PMID: 15459234.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    76. Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease. J Neurosci. 2004 Jul 21; 24(29):6457-65. Fonseca MI, Zhou J, Botto M, Tenner AJ. PMID: 15269255; PMCID: PMC6729885.
      View in: PubMed   Mentions: 160     Fields:    Translation:AnimalsCells
    77. Influence of innate immune responses on autoimmunity. Autoimmunity. 2004 Mar; 37(2):83-4. Tenner AJ. PMID: 15293877.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    78. Complement C1q expression induced by Abeta in rat hippocampal organotypic slice cultures. Exp Neurol. 2004 Feb; 185(2):241-53. Fan R, Tenner AJ. PMID: 14736505.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    79. Neuronal localization of C1q in preclinical Alzheimer's disease. Neurobiol Dis. 2004 Feb; 15(1):40-6. Fonseca MI, Kawas CH, Troncoso JC, Tenner AJ. PMID: 14751769.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    80. Cell surface expression of C1qRP/CD93 is stabilized by O-glycosylation. J Cell Physiol. 2003 Sep; 196(3):512-22. Park M, Tenner AJ. PMID: 12891708.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    81. Human cord blood leukocyte innate immune responses to defense collagens. Pediatr Res. 2003 Nov; 54(5):724-31. Maruyama H, Galvan M, Waffarn F, Tenner AJ. PMID: 12904598.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    82. C1qRp defines a new human stem cell population with hematopoietic and hepatic potential. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10441-5. Danet GH, Luongo JL, Butler G, Lu MM, Tenner AJ, Simon MC, Bonnet DA. PMID: 12140365; PMCID: PMC124933.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    83. Complement in Alzheimer's disease: opportunities for modulating protective and pathogenic events. Neurobiol Aging. 2001 Nov-Dec; 22(6):849-61. Tenner AJ. PMID: 11754992.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    84. C1qR(P), a myeloid cell receptor in blood, is predominantly expressed on endothelial cells in human tissue. J Leukoc Biol. 2001 Nov; 70(5):793-800. Fonseca MI, Carpenter PM, Park M, Palmarini G, Nelson EL, Tenner AJ. PMID: 11698500.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    85. Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease. Am J Pathol. 2001 Apr; 158(4):1345-54. Matsuoka Y, Picciano M, Malester B, LaFrancois J, Zehr C, Daeschner JM, Olschowka JA, Fonseca MI, O'Banion MK, Tenner AJ, Lemere CA, Duff K. PMID: 11290552; PMCID: PMC1891893.
      View in: PubMed   Mentions: 94     Fields:    Translation:AnimalsCells
    86. Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome. Neurobiol Dis. 2001 Apr; 8(2):252-65. Head E, Azizeh BY, Lott IT, Tenner AJ, Cotman CW, Cribbs DH. PMID: 11300721.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    87. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood. 2000 Sep 01; 96(5):1723-32. Yokota T, Oritani K, Takahashi I, Ishikawa J, Matsuyama A, Ouchi N, Kihara S, Funahashi T, Tenner AJ, Tomiyama Y, Matsuzawa Y. PMID: 10961870.
      View in: PubMed   Mentions: 381     Fields:    Translation:HumansAnimalsCells
    88. C1q receptors. Clin Exp Immunol. 2000 Jun; 120(3):406-12. Eggleton P, Tenner AJ, Reid KB. PMID: 10844516; PMCID: PMC1905565.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    89. Molecular dating of senile plaques in the brains of individuals with Down syndrome and in aged dogs. Exp Neurol. 2000 May; 163(1):111-22. Azizeh BY, Head E, Ibrahim MA, Torp R, Tenner AJ, Kim RC, Lott IT, Cotman CW. PMID: 10785449.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    90. Characterization of the murine homolog of C1qR(P): identical cellular expression pattern, chromosomal location and functional activity of the human and murine C1qR(P). Mol Immunol. 2000 May; 37(7):377-89. Kim TS, Park M, Nepomuceno RR, Palmarini G, Winokur S, Cotman CA, Bengtsson U, Tenner AJ. PMID: 11074255.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    91. Structural and functional evidence for microglial expression of C1qR(P), the C1q receptor that enhances phagocytosis. J Leukoc Biol. 2000 Jan; 67(1):109-16. Webster SD, Park M, Fonseca MI, Tenner AJ. PMID: 10648005.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    92. Complement component C1q modulates the phagocytosis of Abeta by microglia. Exp Neurol. 2000 Jan; 161(1):127-38. Webster SD, Yang AJ, Margol L, Garzon-Rodriguez W, Glabe CG, Tenner AJ. PMID: 10683279.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    93. Digestion of C1q collagen-like domain with MMPs-1,-2,-3, and -9 further defines the sequence involved in the stimulation of neutrophil superoxide production. J Leukoc Biol. 1999 Sep; 66(3):416-22. Ruiz S, Henschen-Edman AH, Nagase H, Tenner AJ. PMID: 10496311.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    94. Neuronal protection in stroke by an sLex-glycosylated complement inhibitory protein. Science. 1999 Jul 23; 285(5427):595-9. Huang J, Kim LJ, Mealey R, Marsh HC, Zhang Y, Tenner AJ, Connolly ES, Pinsky DJ. PMID: 10417391.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    95. The presence of isoaspartic acid in beta-amyloid plaques indicates plaque age. Exp Neurol. 1999 Jun; 157(2):277-88. Fonseca MI, Head E, Velazquez P, Cotman CW, Tenner AJ. PMID: 10364440.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    96. The mouse C1q A-chain sequence alters beta-amyloid-induced complement activation. Neurobiol Aging. 1999 May-Jun; 20(3):297-304. Webster SD, Tenner AJ, Poulos TL, Cribbs DH. PMID: 10588577.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    97. C1qRP is a heavily O-glycosylated cell surface protein involved in the regulation of phagocytic activity. J Immunol. 1999 Mar 15; 162(6):3583-9. Nepomuceno RR, Ruiz S, Park M, Tenner AJ. PMID: 10092817.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    98. Membrane receptors for soluble defense collagens. Curr Opin Immunol. 1999 Feb; 11(1):34-41. Tenner AJ. PMID: 10047541.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    99. C1q--how many functions? How many receptors? Trends Cell Biol. 1998 Nov; 8(11):428-31. Eggleton P, Reid KB, Tenner AJ. PMID: 9854308.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    100. C1q receptors: regulating specific functions of phagocytic cells. Immunobiology. 1998 Aug; 199(2):250-64. Tenner AJ. PMID: 9777410.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    101. C1qRP, the C1q receptor that enhances phagocytosis, is detected specifically in human cells of myeloid lineage, endothelial cells, and platelets. J Immunol. 1998 Feb 15; 160(4):1929-35. Nepomuceno RR, Tenner AJ. PMID: 9469455.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    102. Complement activation by cross-linked truncated and chimeric full-length beta-amyloid. Neuroreport. 1997 Nov 10; 8(16):3457-62. Cribbs DH, Velazquez P, Soreghan B, Glabe CG, Tenner AJ. PMID: 9427307.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    103. The progression of beta-amyloid deposition in the frontal cortex of the aged canine. Brain Res. 1997 Nov 07; 774(1-2):35-43. Satou T, Cummings BJ, Head E, Nielson KA, Hahn FF, Milgram NW, Velazquez P, Cribbs DH, Tenner AJ, Cotman CW. PMID: 9452189.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    104. Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease. Neurobiol Aging. 1997 Jul-Aug; 18(4):415-21. Webster S, Lue LF, Brachova L, Tenner AJ, McGeer PL, Terai K, Walker DG, Bradt B, Cooper NR, Rogers J. PMID: 9330973.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    105. cDNA cloning and primary structure analysis of C1qR(P), the human C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro. Immunity. 1997 Feb; 6(2):119-29. Nepomuceno RR, Henschen-Edman AH, Burgess WH, Tenner AJ. PMID: 9047234.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    106. Aspartate residue 7 in amyloid beta-protein is critical for classical complement pathway activation: implications for Alzheimer's disease pathogenesis. Nat Med. 1997 Jan; 3(1):77-9. Velazquez P, Cribbs DH, Poulos TL, Tenner AJ. PMID: 8986745.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    107. beta-Amyloid converts an acute phase injury response to chronic injury responses. Neurobiol Aging. 1996 Sep-Oct; 17(5):723-31. Cotman CW, Tenner AJ, Cummings BJ. PMID: 8892345.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    108. Localization and cell association of C1q in Alzheimer's disease brain. Exp Neurol. 1996 Mar; 138(1):22-32. Afagh A, Cummings BJ, Cribbs DH, Cotman CW, Tenner AJ. PMID: 8593893.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    109. Localization of the site on the complement component C1q required for the stimulation of neutrophil superoxide production. J Biol Chem. 1995 Dec 22; 270(51):30627-34. Ruiz S, Henschen-Edman AH, Tenner AJ. PMID: 8530499.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    110. Mannose binding protein (MBP) enhances mononuclear phagocyte function via a receptor that contains the 126,000 M(r) component of the C1q receptor. Immunity. 1995 Oct; 3(4):485-93. Tenner AJ, Robinson SL, Ezekowitz RA. PMID: 7584139.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    111. Cultured rat microglia express C1q and receptor for C1q: implications for amyloid effects on microglia. Exp Neurol. 1995 Aug; 134(2):214-21. Korotzer AR, Watt J, Cribbs D, Tenner AJ, Burdick D, Glabe C, Cotman CW. PMID: 7556541.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    112. C1q triggers neutrophil superoxide production by a unique CD18-dependent mechanism. J Leukoc Biol. 1995 Aug; 58(2):168-76. Goodman EB, Anderson DC, Tenner AJ. PMID: 7643012.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    113. Decreased levels of C1q in cerebrospinal fluid of living Alzheimer patients correlate with disease state. Neurobiol Aging. 1994 Sep-Oct; 15(5):609-14. Smyth MD, Cribbs DH, Tenner AJ, Shankle WR, Dick M, Kesslak JP, Cotman CW. PMID: 7824052.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    114. beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain. J Immunol. 1994 May 15; 152(10):5050-9. Jiang H, Burdick D, Glabe CG, Cotman CW, Tenner AJ. PMID: 8176223.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    115. Cell-surface protein identified on phagocytic cells modulates the C1q-mediated enhancement of phagocytosis. J Immunol. 1994 Apr 15; 152(8):4005-16. Guan E, Robinson SL, Goodman EB, Tenner AJ. PMID: 8144968.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    116. Functional aspects of the C1q receptors. Behring Inst Mitt. 1993 Dec; (93):241-53. Tenner AJ. PMID: 8172573.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    117. Signal transduction mechanisms of C1q-mediated superoxide production. Evidence for the involvement of temporally distinct staurosporine-insensitive and sensitive pathways. J Immunol. 1992 Jun 15; 148(12):3920-8. Goodman EB, Tenner AJ. PMID: 1318335.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    118. Complement subcomponent C1q stimulates Ig production by human B lymphocytes. J Immunol. 1991 May 15; 146(10):3356-64. Young KR, Ambrus JL, Malbran A, Fauci AS, Tenner AJ. PMID: 1902854.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    119. Complement component C1q enhances invasion of human mononuclear phagocytes and fibroblasts by Trypanosoma cruzi trypomastigotes. J Clin Invest. 1989 Dec; 84(6):1982-9. Rimoldi MT, Tenner AJ, Bobak DA, Joiner KA. PMID: 2687332; PMCID: PMC304081.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    120. Human mannose-binding protein activates the alternative complement pathway and enhances serum bactericidal activity on a mannose-rich isolate of Salmonella. J Clin Invest. 1989 Dec; 84(6):1821-9. Schweinle JE, Ezekowitz RA, Tenner AJ, Kuhlman M, Joiner KA. PMID: 2592561; PMCID: PMC304060.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    121. Human pulmonary surfactant protein (SP-A), a protein structurally homologous to C1q, can enhance FcR- and CR1-mediated phagocytosis. J Biol Chem. 1989 Aug 15; 264(23):13923-8. Tenner AJ, Robinson SL, Borchelt J, Wright JR. PMID: 2788165.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    122. C1q interactions with cell surface receptors. Behring Inst Mitt. 1989 Jul; (84):220-9. Tenner AJ. PMID: 2679535.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    123. C1q acts synergistically with phorbol dibutyrate to activate CR1-mediated phagocytosis by human mononuclear phagocytes. Eur J Immunol. 1988 Dec; 18(12):2001-7. Bobak DA, Frank MM, Tenner AJ. PMID: 2975599.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    124. Enhanced invasion of mononuclear phagocytes by serum-treated Trypanosoma cruzi is due to Clq. Mem Inst Oswaldo Cruz. 1988 Nov; 83 Suppl 1:456-8. Rimoldi MT, Tenner AJ, Bobak DA, Joiner KA. PMID: 3075688.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    125. Modulation of FcR function by complement: subcomponent C1q enhances the phagocytosis of IgG-opsonized targets by human monocytes and culture-derived macrophages. J Immunol. 1987 Feb 15; 138(4):1150-6. Bobak DA, Gaither TA, Frank MM, Tenner AJ. PMID: 3492544.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    126. Activator-bound C1 is less susceptible to inactivation by C1 inhibition than is fluid-phase C1. J Immunol. 1986 Jul 15; 137(2):625-30. Tenner AJ, Frank MM. PMID: 3722818.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    127. Characterization of C1q receptor expression on human phagocytic cells: effects of PDBu and fMLP. J Immunol. 1986 Jun 15; 136(12):4604-10. Bobak DA, Frank MM, Tenner AJ. PMID: 3486907.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    128. Antibody-independent C1 activation by E. coli. J Immunol. 1984 Aug; 133(2):886-91. Tenner AJ, Ziccardi RJ, Cooper NR. PMID: 6376630.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    129. Stimulation of a human polymorphonuclear leukocyte oxidative response by the C1q subunit of the first complement component. J Immunol. 1982 Jun; 128(6):2547-52. Tenner AJ, Cooper NR. PMID: 6281333.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    130. Purification and radiolabeling of human C1q. J Immunol. 1981 Aug; 127(2):648-53. Tenner AJ, Lesavre PH, Cooper NR. PMID: 7252154.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    131. Identification of types of cells in human peripheral blood that bind C1q. J Immunol. 1981 Mar; 126(3):1174-9. Tenner AJ, Cooper NR. PMID: 6970220.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    132. Analysis of receptor-mediated C1q binding to human peripheral blood mononuclear cells. J Immunol. 1980 Oct; 125(4):1658-64. Tenner AJ, Cooper NR. PMID: 7410850.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
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