Qun-Yong Zhou

Title(s)	Professor, Pharmaceutical Sciences
School	School of Pharmacy and Pharmaceutical Sciences
Address	101 Theory, Suite 100 Irvine CA 92697-3958
Phone	(949) 824-2232, 1902
vCard	Download vCard

Research

research activities and funding

Regulation of glucose homeostasis by prokineticin 2 signaling
NIH R21DK091916Aug 5, 2011 - Jul 31, 2014
Role: Principal Investigator

Prokineticin 2 and Suprachiasmatic Circadian Output
NIH R01MH067753Sep 24, 2004 - Jun 30, 2010
Role: Principal Investigator

CONSTITUTIVELY ACTIVE DOPAMINE D1 AND D2 RECEPTORS
NIH R29MH057889Jul 1, 1998 - Jun 30, 2004
Role: Principal Investigator

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Overexpression of Prokineticin 2 in Transgenic Mice Leads to Reduced Circadian Behavioral Rhythmicity and Altered Molecular Rhythms in the Suprachiasmatic Clock. J Circadian Rhythms. 2018 Nov 06; 16:13. Li X, Zhang C, Zhou QY. PMID: 30473715; PMCID: PMC6234414.

View in: PubMed Mentions: 6
Antagonism of EG-VEGF Receptors as Targeted Therapy for Choriocarcinoma Progression In Vitro and In Vivo. Clin Cancer Res. 2017 Nov 15; 23(22):7130-7140. Traboulsi W, Sergent F, Boufettal H, Brouillet S, Slim R, Hoffmann P, Benlahfid M, Zhou QY, Balboni G, Onnis V, Bolze PA, Salomon A, Sauthier P, Mallet F, Aboussaouira T, Feige JJ, Benharouga M, Alfaidy N. PMID: 28899975.

View in: PubMed Mentions: 16 Fields:
Neo Neoplasms
Translation:Humans Animals Cells
Differential arousal regulation by prokineticin 2 signaling in the nocturnal mouse and the diurnal monkey. Mol Brain. 2016 08 18; 9(1):78. Zhou QY, Burton KJ, Neal ML, Qiao Y, Kanthasamy AG, Sun Y, Xu X, Ma Y, Li X. PMID: 27535380; PMCID: PMC4989352.

View in: PubMed Mentions: 2 Fields:
Bra Brain Mol Molecular Biology
Translation:Animals Cells
Expression of prokineticin 2 and its receptor in the macaque monkey brain. Chronobiol Int. 2016; 33(2):191-9. Burton KJ, Li X, Li B, Cheng MY, Urbanski HF, Zhou QY. PMID: 26818846; PMCID: PMC4959799.

View in: PubMed Mentions: 6 Fields:
Phy Physiology
Translation:Animals
Rhythmic Trafficking of TRPV2 in the Suprachiasmatic Nucleus is Regulated by Prokineticin 2 Signaling. J Circadian Rhythms. 2015 Apr 01; 13:2. Burton KJ, Li X, Li JD, Hu WP, Zhou QY. PMID: 27103928; PMCID: PMC4832818.

View in: PubMed Mentions: 5
Signaling role of prokineticin 2 on the estrous cycle of female mice. PLoS One. 2014; 9(3):e90860. Xiao L, Zhang C, Li X, Gong S, Hu R, Balasubramanian R, Crowley W WF, Hastings MH, Zhou QY. PMID: 24633064; PMCID: PMC3954593.

View in: PubMed Mentions: 9 Fields:
Med Medicine (General)Sci Science
Translation:Animals
Prokineticin 2 is involved in the thermoregulation and energy expenditure. Regul Pept. 2012 Nov 10; 179(1-3):84-90. Zhou W, Li JD, Hu WP, Cheng MY, Zhou QY. PMID: 22960406.

View in: PubMed Mentions: 12 Fields:
Bio Biochemistry
Translation:Animals Cells
Safety profile and cellular uptake of biotemplated nanocapsules with nanometre-thin walls. Nanoscale. 2011 Jun; 3(6):2576-82. Zhou Q, Dergunov SA, Zhang Y, Li X, Mu Q, Zhang Q, Jiang G, Pinkhassik E, Yan B. PMID: 21509382.

View in: PubMed Mentions: 1 Fields:
Nan Nanotechnology
Translation:Humans Cells
Decreased REM sleep and altered circadian sleep regulation in mice lacking vasoactive intestinal polypeptide. Sleep. 2011 Jan 01; 34(1):49-56. Hu WP, Li JD, Colwell CS, Zhou QY. PMID: 21203371; PMCID: PMC3001794.

View in: PubMed Mentions: 8 Fields:
Psy Psychophysiology
Translation:Animals
Efferent projections of prokineticin 2 expressing neurons in the mouse suprachiasmatic nucleus. PLoS One. 2009 Sep 28; 4(9):e7151. Zhang C, Truong KK, Zhou QY. PMID: 19784373; PMCID: PMC2747004.

View in: PubMed Mentions: 35 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
Vasopressin receptor V1a regulates circadian rhythms of locomotor activity and expression of clock-controlled genes in the suprachiasmatic nuclei. Am J Physiol Regul Integr Comp Physiol. 2009 Mar; 296(3):R824-30. Li JD, Burton KJ, Zhang C, Hu SB, Zhou QY. PMID: 19052319; PMCID: PMC2665843.

View in: PubMed Mentions: 53 Fields:
Phy Physiology
Disruption of the circadian output molecule prokineticin 2 results in anxiolytic and antidepressant-like effects in mice. Neuropsychopharmacology. 2009 Jan; 34(2):367-73. Li JD, Hu WP, Zhou QY. PMID: 18432189; PMCID: PMC2667318.

View in: PubMed Mentions: 17 Fields:
Neu Neurology Psy Psychopharmacology
Biological function of prokineticins. Results Probl Cell Differ. 2008; 46:181-99. Zhou QY, Meidan R. PMID: 18202926.

View in: PubMed Mentions: 7 Fields:
Cel Cell Biology
Translation:Humans Animals Cells
Origin, migration and fate of newly generated neurons in the adult rodent piriform cortex. Brain Struct Funct. 2007 Sep; 212(2):133-48. Shapiro LA, Ng KL, Kinyamu R, Whitaker-Azmitia P, Geisert EE, Blurton-Jones M, Zhou QY, Ribak CE. PMID: 17764016.

View in: PubMed Mentions: 24 Fields:
Bra Brain
Translation:Animals Cells
Olfactory enrichment enhances the survival of newly born cortical neurons in adult mice. Neuroreport. 2007 Jul 02; 18(10):981-5. Shapiro LA, Ng KL, Zhou QY, Ribak CE. PMID: 17558281.

View in: PubMed Mentions: 7 Fields:
Neu Neurology
Translation:Animals Cells
Altered circadian and homeostatic sleep regulation in prokineticin 2-deficient mice. Sleep. 2007 Mar; 30(3):247-56. Hu WP, Li JD, Zhang C, Boehmer L, Siegel JM, Zhou QY. PMID: 17425220; PMCID: PMC2673012.

View in: PubMed Mentions: 31 Fields:
Psy Psychophysiology
Prokineticin 2 is a target gene of proneural basic helix-loop-helix factors for olfactory bulb neurogenesis. J Biol Chem. 2007 Mar 09; 282(10):6917-21. Zhang C, Ng KL, Li JD, He F, Anderson DJ, Sun YE, Zhou QY. PMID: 17259180.

View in: PubMed Mentions: 12 Fields:
Bio Biochemistry
Translation:Animals Cells
The prokineticins: a novel pair of regulatory peptides. Mol Interv. 2006 Dec; 6(6):330-8. Zhou QY. PMID: 17200460; PMCID: PMC2667320.

View in: PubMed Mentions: 11 Fields:
Mol Molecular Biology Pha Pharmacology
Impaired pain sensation in mice lacking prokineticin 2. Mol Pain. 2006 Nov 15; 2:35. Hu WP, Zhang C, Li JD, Luo ZD, Amadesi S, Bunnett N, Zhou QY. PMID: 17107623; PMCID: PMC1660571.

View in: PubMed Mentions: 20 Fields:
Mol Molecular Biology Neu Neurology Psy Psychophysiology
Translation:Animals Cells
Attenuated circadian rhythms in mice lacking the prokineticin 2 gene. J Neurosci. 2006 Nov 08; 26(45):11615-23. Li JD, Hu WP, Boehmer L, Cheng MY, Lee AG, Jilek A, Siegel JM, Zhou QY. PMID: 17093083; PMCID: PMC2713041.

View in: PubMed Mentions: 57 Fields:
Neu Neurology
Expression of prokineticins and their receptors in the adult mouse brain. J Comp Neurol. 2006 Oct 20; 498(6):796-809. Cheng MY, Leslie FM, Zhou QY. PMID: 16927269; PMCID: PMC2667319.

View in: PubMed Mentions: 52 Fields:
Neu Neurology
Prokineticin 2 and circadian clock output. FEBS J. 2005 Nov; 272(22):5703-9. Zhou QY, Cheng MY. PMID: 16279936; PMCID: PMC2667323.

View in: PubMed Mentions: 32 Fields:
Bio Biochemistry
Dependence of olfactory bulb neurogenesis on prokineticin 2 signaling. Science. 2005 Jun 24; 308(5730):1923-7. Ng KL, Li JD, Cheng MY, Leslie FM, Lee AG, Zhou QY. PMID: 15976302.

View in: PubMed Mentions: 110 Fields:
Sci Science
Translation:Animals Cells
Regulation of prokineticin 2 expression by light and the circadian clock. BMC Neurosci. 2005 Mar 11; 6:17. Cheng MY, Bittman EL, Hattar S, Zhou QY. PMID: 15762991; PMCID: PMC555564.

View in: PubMed Mentions: 25 Fields:
Neu Neurology
Translation:Animals
Structural determinants required for the bioactivities of prokineticins and identification of prokineticin receptor antagonists. Mol Pharmacol. 2004 Mar; 65(3):582-8. Bullock CM, Li JD, Zhou QY. PMID: 14978236.

View in: PubMed Mentions: 36 Fields:
Mol Molecular Biology Pha Pharmacology
Translation:Animals Cells
Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus. Nature. 2002 May 23; 417(6887):405-10. Cheng MY, Bullock CM, Li C, Lee AG, Bermak JC, Belluzzi J, Weaver DR, Leslie FM, Zhou QY. PMID: 12024206.

View in: PubMed Mentions: 198 Fields:
Sci Science
Translation:Humans Animals Cells
Association of dopamine D(3) receptors with actin-binding protein 280 (ABP-280). Biochem Pharmacol. 2002 Mar 01; 63(5):859-63. Li M, Li C, Weingarten P, Bunzow JR, Grandy DK, Zhou QY. PMID: 11911837.

View in: PubMed Mentions: 11 Fields:
Bio Biochemistry Pha Pharmacology
Translation:Humans Cells
Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus. Eur J Cell Biol. 2002 Feb; 81(2):77-85. Bermak JC, Li M, Bullock C, Weingarten P, Zhou QY. PMID: 11893085.

View in: PubMed Mentions: 6 Fields:
Cel Cell Biology
Translation:Humans Animals Cells