Cahalan, Michael

InstitutionUniversity of California, Irvine
DepartmentPhysiology and Biophysics
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-7776
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Cellular and Molecular Mechanisms of Regulatory T Cells in EAE
    NIH/NIAID R01AI121945Jun 20, 2016 - Jan 31, 2021
    Role: Principal Investigator
    Cellular and Molecular Mechanisms of Regulatory T Cells in EAE
    NIH/NIAID R56AI121945Feb 5, 2016 - Jan 31, 2017
    Role: Principal Investigator
    A Transgenic Mouse Line to Map Cell-Type Specific Calcium Signals In Vivo
    NIH/NIAID R21AI117555Feb 1, 2015 - Jan 31, 2017
    Role: Principal Investigator
    Immunology Research Training Grant
    NIH/NIAID T32AI060573Jul 1, 2004 - Jul 31, 2021
    Role: Co-Principal Investigator
    NIH/NCI S15CA055990Aug 1, 1991 - Jul 31, 1992
    Role: Principal Investigator
    NIH/NCRR S10RR005912Jun 1, 1990 - Dec 31, 1991
    Role: Principal Investigator
    NIH/NIAID R01AI021808Dec 1, 1984 - Nov 30, 1987
    Role: Principal Investigator
    Functional immuno-imaging of lymphocyte motility and cell interactions in lymph n
    NIH/NIGMS R01GM041514May 1, 1984 - Mar 31, 2014
    Role: Principal Investigator
    NIH/NINDS K04NS000662Jul 1, 1981 - Jun 30, 1986
    Role: Principal Investigator
    Molecular Mechanisms of lon Channels in T Lymphocytes
    NIH/NINDS R56NS014609Sep 15, 1978 - Jul 31, 2019
    Role: Principal Investigator
    Molecular Mechanisms of Ion Channels in T Lymphocytes
    NIH/NINDS R01NS014609Sep 15, 1978 - Mar 31, 2018
    Role: Principal Investigator
    Molecular Mechanisms of Ion Channels in T Lymphocytes
    NIH/NINDS R37NS014609Sep 15, 1978 - Mar 31, 2013
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Dong TX, Othy S, Greenberg ML, Jairaman A, Akunwafo C, Leverrier S, Yu Y, Parker I, Dynes JL, Cahalan MD. Intermittent Ca2+ signals mediated by Orai1 regulate basal T cell motility. Elife. 2017 12 14; 6. PMID: 29239723.
      View in: PubMed
    2. Dong TX, Othy S, Jairaman A, Skupsky J, Zavala A, Parker I, Dynes JL, Cahalan MD. T-cell calcium dynamics visualized in a ratiometric tdTomato-GCaMP6f transgenic reporter mouse. Elife. 2017 12 14; 6. PMID: 29239725.
      View in: PubMed
    3. Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, Gylys KH, Cahalan MD, Cummings BJ, Antel JP, Mortazavi A, Carson MJ, Poon WW, Blurton-Jones M. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 2017 Apr 19; 94(2):278-293.e9. PMID: 28426964.
      View in: PubMed
    4. Dynes JL, Amcheslavsky A, Cahalan MD. Genetically targeted single-channel optical recording reveals multiple Orai1 gating states and oscillations in calcium influx. Proc Natl Acad Sci U S A. 2016 Jan 12; 113(2):440-5. PMID: 26712003; PMCID: PMC4720334.
    5. Perni S, Dynes JL, Yeromin AV, Cahalan MD, Franzini-Armstrong C. Nanoscale patterning of STIM1 and Orai1 during store-operated Ca2+ entry. Proc Natl Acad Sci U S A. 2015 Oct 06; 112(40):E5533-42. PMID: 26351694; PMCID: PMC4603497.
    6. Weinger JG, Greenberg ML, Matheu MP, Parker I, Walsh CM, Lane TE, Cahalan MD. Two-photon imaging of cellular dynamics in the mouse spinal cord. J Vis Exp. 2015 Feb 22; (96). PMID: 25742043; PMCID: PMC4354666.
    7. Matheu MP, Othy S, Greenberg ML, Dong TX, Schuijs M, Deswarte K, Hammad H, Lambrecht BN, Parker I, Cahalan MD. Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming. Nat Commun. 2015 Feb 05; 6:6219. PMID: 25653051; PMCID: PMC4347855.
    8. Amcheslavsky A, Wood ML, Yeromin AV, Parker I, Freites JA, Tobias DJ, Cahalan MD. Molecular biophysics of Orai store-operated Ca2+ channels. Biophys J. 2015 Jan 20; 108(2):237-46. PMID: 25606672; PMCID: PMC4302196.
    9. Marro BS, Blanc CA, Loring JF, Cahalan MD, Lane TE. Promoting remyelination: utilizing a viral model of demyelination to assess cell-based therapies. Expert Rev Neurother. 2014 Oct; 14(10):1169-79. PMID: 25245576; PMCID: PMC4232205.
    10. Greenberg ML, Weinger JG, Matheu MP, Carbajal KS, Parker I, Macklin WB, Lane TE, Cahalan MD. Two-photon imaging of remyelination of spinal cord axons by engrafted neural precursor cells in a viral model of multiple sclerosis. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):E2349-55. PMID: 24843159; PMCID: PMC4050611.
    11. Amcheslavsky A, Safrina O, Cahalan MD. State-dependent block of Orai3 TM1 and TM3 cysteine mutants: insights into 2-APB activation. J Gen Physiol. 2014 May; 143(5):621-31. PMID: 24733836; PMCID: PMC4003185.
    12. Amcheslavsky A, Safrina O, Cahalan MD. Orai3 TM3 point mutation G158C alters kinetics of 2-APB-induced gating by disulfide bridge formation with TM2 C101. J Gen Physiol. 2013 Oct; 142(4):405-12. PMID: 24081982; PMCID: PMC3787773.
    13. Matheu MP, Teijaro JR, Walsh KB, Greenberg ML, Marsolais D, Parker I, Rosen H, Oldstone MB, Cahalan MD. Three phases of CD8 T cell response in the lung following H1N1 influenza infection and sphingosine 1 phosphate agonist therapy. PLoS One. 2013; 8(3):e58033. PMID: 23533579; PMCID: PMC3606384.
    14. Greenberg ML, Yu Y, Leverrier S, Zhang SL, Parker I, Cahalan MD. Orai1 function is essential for T cell homing to lymph nodes. J Immunol. 2013 Apr 01; 190(7):3197-206. PMID: 23455504; PMCID: PMC3608704.
    15. Germain RN, Robey EA, Cahalan MD. A decade of imaging cellular motility and interaction dynamics in the immune system. Science. 2012 Jun 29; 336(6089):1676-81. PMID: 22745423.
      View in: PubMed
    16. Matheu MP, Su Y, Greenberg ML, Blanc CA, Parker I, Scott DW, Cahalan MD. Toll-like receptor 4-activated B cells out-compete Toll-like receptor 9-activated B cells to establish peripheral immunological tolerance. Proc Natl Acad Sci U S A. 2012 May 15; 109(20):E1258-66. PMID: 22511718; PMCID: PMC3356607.
    17. Khadra N, Bresson-Bepoldin L, Penna A, Chaigne-Delalande B, Ségui B, Levade T, Vacher AM, Reiffers J, Ducret T, Moreau JF, Cahalan MD, Vacher P, Legembre P. CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) ß2, and prevents death-inducing signaling complex formation. Proc Natl Acad Sci U S A. 2011 Nov 22; 108(47):19072-7. PMID: 22065776; PMCID: PMC3223456.
    18. Zhang SL, Yeromin AV, Hu J, Amcheslavsky A, Zheng H, Cahalan MD. Mutations in Orai1 transmembrane segment 1 cause STIM1-independent activation of Orai1 channels at glycine 98 and channel closure at arginine 91. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):17838-43. PMID: 21987804; PMCID: PMC3203763.
    19. Demuro A, Penna A, Safrina O, Yeromin AV, Amcheslavsky A, Cahalan MD, Parker I. Subunit stoichiometry of human Orai1 and Orai3 channels in closed and open states. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):17832-7. PMID: 21987805; PMCID: PMC3203769.
    20. Khorshidi MA, Vanherberghen B, Kowalewski JM, Garrod KR, Lindström S, Andersson-Svahn H, Brismar H, Cahalan MD, Önfelt B. Analysis of transient migration behavior of natural killer cells imaged in situ and in vitro. Integr Biol (Camb). 2011 Jul; 3(7):770-8. PMID: 21687858.
      View in: PubMed
    21. Cahalan MD. Imaging transplant rejection: a new view. Nat Med. 2011 Jun; 17(6):662-3. PMID: 21647143.
      View in: PubMed
    22. Matheu MP, Cahalan MD, Parker I. In situ lymph node imaging. Cold Spring Harb Protoc. 2011 Feb 01; 2011(2):pdb.prot5567. PMID: 21285267.
      View in: PubMed
    23. Matheu MP, Cahalan MD, Parker I. Induction of an immune response for imaging antigen-presenting cell/T-cell interactions. Cold Spring Harb Protoc. 2011 Feb 01; 2011(2):pdb.prot5566. PMID: 21285266.
      View in: PubMed
    24. Matheu MP, Cahalan MD, Parker I. In vivo lymph node imaging. Cold Spring Harb Protoc. 2011 Feb 01; 2011(2):pdb.prot5568. PMID: 21285268.
      View in: PubMed
    25. Matheu MP, Cahalan MD, Parker I. General approach to adoptive transfer and cell labeling for immunoimaging. Cold Spring Harb Protoc. 2011 Feb 01; 2011(2):pdb.prot5565. PMID: 21285265.
      View in: PubMed
    26. Matheu MP, Cahalan MD, Parker I. Immunoimaging: studying immune system dynamics using two-photon microscopy. Cold Spring Harb Protoc. 2011 Feb 01; 2011(2):pdb.top99. PMID: 21285279.
      View in: PubMed
    27. Newton RH, Leverrier S, Srikanth S, Gwack Y, Cahalan MD, Walsh CM. Protein kinase D orchestrates the activation of DRAK2 in response to TCR-induced Ca2+ influx and mitochondrial reactive oxygen generation. J Immunol. 2011 Jan 15; 186(2):940-50. PMID: 21148796; PMCID: PMC3133617.
    28. Flach H, Rosenbaum M, Duchniewicz M, Kim S, Zhang SL, Cahalan MD, Mittler G, Grosschedl R. Mzb1 protein regulates calcium homeostasis, antibody secretion, and integrin activation in innate-like B cells. Immunity. 2010 Nov 24; 33(5):723-35. PMID: 21093319; PMCID: PMC3125521.
    29. Cahalan MD. Cell biology. How to STIMulate calcium channels. Science. 2010 Oct 01; 330(6000):43-4. PMID: 20929798; PMCID: PMC3133971.
    30. Krummel MF, Cahalan MD. The immunological synapse: a dynamic platform for local signaling. J Clin Immunol. 2010 May; 30(3):364-72. PMID: 20390326; PMCID: PMC2874029.
    31. Sen D, Forrest L, Kepler TB, Parker I, Cahalan MD. Selective and site-specific mobilization of dermal dendritic cells and Langerhans cells by Th1- and Th2-polarizing adjuvants. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8334-9. PMID: 20404167; PMCID: PMC2889549.
    32. Garrod KR, Liu FC, Forrest LE, Parker I, Kang SM, Cahalan MD. NK cell patrolling and elimination of donor-derived dendritic cells favor indirect alloreactivity. J Immunol. 2010 Mar 01; 184(5):2329-36. PMID: 20139277; PMCID: PMC3125519.
    33. Cahalan MD, Chandy KG. The functional network of ion channels in T lymphocytes. Immunol Rev. 2009 Sep; 231(1):59-87. PMID: 19754890; PMCID: PMC3133616.
    34. Cahalan MD. STIMulating store-operated Ca(2+) entry. Nat Cell Biol. 2009 Jun; 11(6):669-77. PMID: 19488056; PMCID: PMC2721799.
    35. Yu Y, Keller SH, Remillard CV, Safrina O, Nicholson A, Zhang SL, Jiang W, Vangala N, Landsberg JW, Wang JY, Thistlethwaite PA, Channick RN, Robbins IM, Loyd JE, Ghofrani HA, Grimminger F, Schermuly RT, Cahalan MD, Rubin LJ, Yuan JX. A functional single-nucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension. Circulation. 2009 May 05; 119(17):2313-22. PMID: 19380626; PMCID: PMC2749566.
    36. Matheu MP, Beeton C, Garcia A, Chi V, Rangaraju S, Safrina O, Monaghan K, Uemura MI, Li D, Pal S, de la Maza LM, Monuki E, Flügel A, Pennington MW, Parker I, Chandy KG, Cahalan MD. Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block. Immunity. 2008 Oct 17; 29(4):602-14. PMID: 18835197; PMCID: PMC2732399.
    37. Sen D, Deerinck TJ, Ellisman MH, Parker I, Cahalan MD. Quantum dots for tracking dendritic cells and priming an immune response in vitro and in vivo. PLoS One. 2008 Sep 29; 3(9):e3290. PMID: 18820727; PMCID: PMC2538605.
    38. Penna A, Demuro A, Yeromin AV, Zhang SL, Safrina O, Parker I, Cahalan MD. The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Nature. 2008 Nov 06; 456(7218):116-20. PMID: 18820677; PMCID: PMC2597643.
    39. Matheu MP, Sen D, Cahalan MD, Parker I. Generation of bone marrow derived murine dendritic cells for use in 2-photon imaging. J Vis Exp. 2008 Jul 09; (17). PMID: 19066518; PMCID: PMC3278326.
    40. Zhang SL, Kozak JA, Jiang W, Yeromin AV, Chen J, Yu Y, Penna A, Shen W, Chi V, Cahalan MD. Store-dependent and -independent modes regulating Ca2+ release-activated Ca2+ channel activity of human Orai1 and Orai3. J Biol Chem. 2008 Jun 20; 283(25):17662-71. PMID: 18420579; PMCID: PMC2427323.
    41. Lioudyno MI, Kozak JA, Penna A, Safrina O, Zhang SL, Sen D, Roos J, Stauderman KA, Cahalan MD. Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation. Proc Natl Acad Sci U S A. 2008 Feb 12; 105(6):2011-6. PMID: 18250319; PMCID: PMC2538873.
    42. Garrod KR, Cahalan MD. Murine skin transplantation. J Vis Exp. 2008 Jan 16; (11). PMID: 19066559; PMCID: PMC2582837.
    43. Cahalan MD, Parker I. Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs. Annu Rev Immunol. 2008; 26:585-626. PMID: 18173372; PMCID: PMC2732400.
    44. Matheu MP, Cahalan MD. Isolation of CD4+ T cells from mouse lymph nodes using Miltenyi MACS purification. J Vis Exp. 2007; (9):409. PMID: 18989449; PMCID: PMC2566326.
    45. Matheu MP, Parker I, Cahalan MD. Dissection and 2-photon imaging of peripheral lymph nodes in mice. J Vis Exp. 2007; (7):265. PMID: 18989436; PMCID: PMC2565854.
    46. Penna A, Cahalan M. Western Blotting using the Invitrogen NuPage Novex Bis Tris minigels. J Vis Exp. 2007; (7):264. PMID: 18989435; PMCID: PMC2565856.
    47. Matheu MP, Deane JA, Parker I, Fruman DA, Cahalan MD. Class IA phosphoinositide 3-kinase modulates basal lymphocyte motility in the lymph node. J Immunol. 2007 Aug 15; 179(4):2261-9. PMID: 17675487.
      View in: PubMed
    48. Wei SH, Safrina O, Yu Y, Garrod KR, Cahalan MD, Parker I. Ca2+ signals in CD4+ T cells during early contacts with antigen-bearing dendritic cells in lymph node. J Immunol. 2007 Aug 01; 179(3):1586-94. PMID: 17641025.
      View in: PubMed
    49. Zhang S, Cahalan MD. Purifying plasmid DNA from bacterial colonies using the QIAGEN Miniprep Kit. J Vis Exp. 2007; (6):247. PMID: 18997895; PMCID: PMC2557117.
    50. Garrod KR, Wei SH, Parker I, Cahalan MD. Natural killer cells actively patrol peripheral lymph nodes forming stable conjugates to eliminate MHC-mismatched targets. Proc Natl Acad Sci U S A. 2007 Jul 17; 104(29):12081-6. PMID: 17609379; PMCID: PMC1924574.
    51. Cahalan MD, Zhang SL, Yeromin AV, Ohlsen K, Roos J, Stauderman KA. Molecular basis of the CRAC channel. Cell Calcium. 2007 Aug; 42(2):133-44. PMID: 17482674; PMCID: PMC2735391.
    52. Yeromin AV, Zhang SL, Jiang W, Yu Y, Safrina O, Cahalan MD. Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai. Nature. 2006 Sep 14; 443(7108):226-9. PMID: 16921385; PMCID: PMC2756048.
    53. Sanna MG, Wang SK, Gonzalez-Cabrera PJ, Don A, Marsolais D, Matheu MP, Wei SH, Parker I, Jo E, Cheng WC, Cahalan MD, Wong CH, Rosen H. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo. Nat Chem Biol. 2006 Aug; 2(8):434-41. PMID: 16829954.
      View in: PubMed
    54. Cahalan MD, Parker I. Imaging the choreography of lymphocyte trafficking and the immune response. Curr Opin Immunol. 2006 Aug; 18(4):476-82. PMID: 16765574; PMCID: PMC2749663.
    55. Zhang SL, Yeromin AV, Zhang XH, Yu Y, Safrina O, Penna A, Roos J, Stauderman KA, Cahalan MD. Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity. Proc Natl Acad Sci U S A. 2006 Jun 13; 103(24):9357-62. PMID: 16751269; PMCID: PMC1482614.
    56. Cahalan MD, Gutman GA. The sense of place in the immune system. Nat Immunol. 2006 Apr; 7(4):329-32. PMID: 16550194; PMCID: PMC2752360.
    57. Wei SH, Rosen H, Matheu MP, Sanna MG, Wang SK, Jo E, Wong CH, Parker I, Cahalan MD. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses. Nat Immunol. 2005 Dec; 6(12):1228-35. PMID: 16273098.
      View in: PubMed
    58. Cahalan MD, Parker I. Close encounters of the first and second kind: T-DC and T-B interactions in the lymph node. Semin Immunol. 2005 Dec; 17(6):442-51. PMID: 16263308; PMCID: PMC2953541.
    59. Kozak JA, Matsushita M, Nairn AC, Cahalan MD. Charge screening by internal pH and polyvalent cations as a mechanism for activation, inhibition, and rundown of TRPM7/MIC channels. J Gen Physiol. 2005 Nov; 126(5):499-514. PMID: 16260839; PMCID: PMC2266608.
    60. Zhang SL, Yu Y, Roos J, Kozak JA, Deerinck TJ, Ellisman MH, Stauderman KA, Cahalan MD. STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane. Nature. 2005 Oct 06; 437(7060):902-5. PMID: 16208375; PMCID: PMC1618826.
    61. Zinselmeyer BH, Dempster J, Gurney AM, Wokosin D, Miller M, Ho H, Millington OR, Smith KM, Rush CM, Parker I, Cahalan M, Brewer JM, Garside P. In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. J Exp Med. 2005 Jun 06; 201(11):1815-23. PMID: 15928201.
      View in: PubMed
    62. Okada T, Miller MJ, Parker I, Krummel MF, Neighbors M, Hartley SB, O'Garra A, Cahalan MD, Cyster JG. Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. PLoS Biol. 2005 Jun; 3(6):e150. PMID: 15857154; PMCID: PMC1088276.
    63. Roos J, DiGregorio PJ, Yeromin AV, Ohlsen K, Lioudyno M, Zhang S, Safrina O, Kozak JA, Wagner SL, Cahalan MD, Veliçelebi G, Stauderman KA. STIM1, an essential and conserved component of store-operated Ca2+ channel function. J Cell Biol. 2005 May 09; 169(3):435-45. PMID: 15866891; PMCID: PMC2171946.
    64. Matsushita M, Kozak JA, Shimizu Y, McLachlin DT, Yamaguchi H, Wei FY, Tomizawa K, Matsui H, Chait BT, Cahalan MD, Nairn AC. Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1. J Biol Chem. 2005 May 27; 280(21):20793-803. PMID: 15781465.
      View in: PubMed
    65. Cahalan MD. STOP! In the name of positive selection. Nat Immunol. 2005 Feb; 6(2):126-8. PMID: 15662438.
      View in: PubMed
    66. Miller MJ, Safrina O, Parker I, Cahalan MD. Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes. J Exp Med. 2004 Oct 04; 200(7):847-56. PMID: 15466619; PMCID: PMC2213293.
    67. Chandy KG, Wulff H, Beeton C, Pennington M, Gutman GA, Cahalan MD. K+ channels as targets for specific immunomodulation. Trends Pharmacol Sci. 2004 May; 25(5):280-9. PMID: 15120495; PMCID: PMC2749963.
    68. Yeromin AV, Roos J, Stauderman KA, Cahalan MD. A store-operated calcium channel in Drosophila S2 cells. J Gen Physiol. 2004 Feb; 123(2):167-82. PMID: 14744989; PMCID: PMC2217434.
    69. Miller MJ, Hejazi AS, Wei SH, Cahalan MD, Parker I. T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node. Proc Natl Acad Sci U S A. 2004 Jan 27; 101(4):998-1003. PMID: 14722354; PMCID: PMC327133.
    70. Kolski-Andreaco A, Tomita H, Shakkottai VG, Gutman GA, Cahalan MD, Gargus JJ, Chandy KG. SK3-1C, a dominant-negative suppressor of SKCa and IKCa channels. J Biol Chem. 2004 Feb 20; 279(8):6893-904. PMID: 14638680.
      View in: PubMed
    71. Fomina AF, Deerinck TJ, Ellisman MH, Cahalan MD. Regulation of membrane trafficking and subcellular organization of endocytic compartments revealed with FM1-43 in resting and activated human T cells. Exp Cell Res. 2003 Nov 15; 291(1):150-66. PMID: 14597416; PMCID: PMC2749753.
    72. Wei SH, Parker I, Miller MJ, Cahalan MD. A stochastic view of lymphocyte motility and trafficking within the lymph node. Immunol Rev. 2003 Oct; 195:136-59. PMID: 12969316.
      View in: PubMed
    73. Cahalan MD, Parker I, Wei SH, Miller MJ. Real-time imaging of lymphocytes in vivo. Curr Opin Immunol. 2003 Aug; 15(4):372-7. PMID: 12900266; PMCID: PMC2953535.
    74. Kerschbaum HH, Kozak JA, Cahalan MD. Polyvalent cations as permeant probes of MIC and TRPM7 pores. Biophys J. 2003 Apr; 84(4):2293-305. PMID: 12668438; PMCID: PMC1302796.
    75. Miller MJ, Wei SH, Cahalan MD, Parker I. Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2604-9. PMID: 12601158; PMCID: PMC151387.
    76. Kozak JA, Cahalan MD. MIC channels are inhibited by internal divalent cations but not ATP. Biophys J. 2003 Feb; 84(2 Pt 1):922-7. PMID: 12547774; PMCID: PMC1302670.
    77. Beeton C, Wulff H, Singh S, Botsko S, Crossley G, Gutman GA, Cahalan MD, Pennington M, Chandy KG. A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes. J Biol Chem. 2003 Mar 14; 278(11):9928-37. PMID: 12511563.
      View in: PubMed
    78. Cahalan MD, Parker I, Wei SH, Miller MJ. Two-photon tissue imaging: seeing the immune system in a fresh light. Nat Rev Immunol. 2002 Nov; 2(11):872-80. PMID: 12415310; PMCID: PMC2749751.
    79. Kozak JA, Kerschbaum HH, Cahalan MD. Distinct properties of CRAC and MIC channels in RBL cells. J Gen Physiol. 2002 Aug; 120(2):221-35. PMID: 12149283; PMCID: PMC2234455.
    80. Miller MJ, Wei SH, Parker I, Cahalan MD. Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science. 2002 Jun 07; 296(5574):1869-73. PMID: 12016203.
      View in: PubMed
    81. Cahalan MD. The ins and outs of polycystin-2 as a calcium release channel. Nat Cell Biol. 2002 Mar; 4(3):E56-7. PMID: 11875447.
      View in: PubMed
    82. Wei SH, Miller MJ, Cahalan MD, Parker I. Two-photon imaging in intact lymphoid tissue. Adv Exp Med Biol. 2002; 512:203-8. PMID: 12405205.
      View in: PubMed
    83. Ayabe T, Wulff H, Darmoul D, Cahalan MD, Chandy KG, Ouellette AJ. Modulation of mouse Paneth cell alpha-defensin secretion by mIKCa1, a Ca2+-activated, intermediate conductance potassium channel. J Biol Chem. 2002 Feb 01; 277(5):3793-800. PMID: 11724775.
      View in: PubMed
    84. Cahalan MD, Wulff H, Chandy KG. Molecular properties and physiological roles of ion channels in the immune system. J Clin Immunol. 2001 Jul; 21(4):235-52. PMID: 11506193.
      View in: PubMed
    85. Cahalan MD, Chandy KG. Ion channels in the immune system as targets for immunosuppression. Curr Opin Biotechnol. 1997 Dec; 8(6):749-56. PMID: 9425667.
      View in: PubMed
    Michael's Networks
    Derived automatically from this person's publications.
    People in Profiles who have published with this person.
    Related Authors
    People who share related concepts with this person.