Jonathan Skupsky

Title(s)Assistant Health Sciences Professor, Medicine
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-6745
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gulf War Illness Is Associated with Host Gut Microbiome Dysbiosis and Is Linked to Altered Species Abundance in Veterans from the BBRAIN Cohort. Int J Environ Res Public Health. 2024 Aug 21; 21(8). Trivedi A, Bose D, Moffat K, Pearson E, Walsh D, Cohen D, Skupsky J, Chao L, Golier J, Janulewicz P, Sullivan K, Krengel M, Tuteja A, Klimas N, Chatterjee S. PMID: 39200711; PMCID: PMC11354743.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Effect of knocking out mouse Slc44a4 on colonic uptake of the microbiota-generated thiamine pyrophosphate and colon physiology. Am J Physiol Gastrointest Liver Physiol. 2024 Jul 01; 327(1):G36-G46. Sabui S, Anthonymuthu S, Ramamoorthy K, Skupsky J, Jennings TSK, Rahmatpanah F, Fleckenstein JM, Said HM. PMID: 38713615; PMCID: PMC11376973.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    3. Prolonged Antibiotic Use in a Preclinical Model of Gulf War Chronic Multisymptom-Illness Causes Renal Fibrosis-like Pathology via Increased micro-RNA 21-Induced PTEN Inhibition That Is Correlated with Low Host Lachnospiraceae Abundance. Cells. 2023 12 27; 13(1). Trivedi A, Bose D, Saha P, Roy S, More M, Skupsky J, Klimas NG, Chatterjee S. PMID: 38201260; PMCID: PMC10777912.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Biotin Deficiency Induces Intestinal Dysbiosis Associated with an Inflammatory Bowel Disease-like Phenotype. Nutrients. 2023 Jan 04; 15(2). Yang JC, Jacobs JP, Hwang M, Sabui S, Liang F, Said HM, Skupsky J. PMID: 36678135; PMCID: PMC9866305.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    5. Biotin Supplementation Ameliorates Murine Colitis by Preventing NF-κB Activation. Cell Mol Gastroenterol Hepatol. 2020; 9(4):557-567. Skupsky J, Sabui S, Hwang M, Nakasaki M, Cahalan MD, Said HM. PMID: 31786364; PMCID: PMC7078531.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    6. Tamoxifen-induced, intestinal-specific deletion of Slc5a6 in adult mice leads to spontaneous inflammation: involvement of NF-κB, NLRP3, and gut microbiota. Am J Physiol Gastrointest Liver Physiol. 2019 10 01; 317(4):G518-G530. Sabui S, Skupsky J, Kapadia R, Cogburn K, Lambrecht NW, Agrawal A, Said HM. PMID: 31369292; PMCID: PMC6842991.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    7. T-cell calcium dynamics visualized in a ratiometric tdTomato-GCaMP6f transgenic reporter mouse. Elife. 2017 12 14; 6. Dong TX, Othy S, Jairaman A, Skupsky J, Zavala A, Parker I, Dynes JL, Cahalan MD. PMID: 29239725; PMCID: PMC5747524.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    8. Current hepatitis B treatment guidelines and future research directions. Front Med. 2014 Jun; 8(2):145-57. Skupsky J, Hu KQ. PMID: 24871443.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. STAT6 controls the number of regulatory T cells in vivo, thereby regulating allergic lung inflammation. J Immunol. 2013 Aug 15; 191(4):1517-28. Dorsey NJ, Chapoval SP, Smith EP, Skupsky J, Scott DW, Keegan AD. PMID: 23825312; PMCID: PMC3735779.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    10. B cells "transduced" with TAT-fusion proteins can induce tolerance and protect mice from diabetes and EAE. Clin Immunol. 2011 Sep; 140(3):260-7. Su Y, Zhang AH, Li X, Owusu-Boaitey N, Skupsky J, Scott DW. PMID: 21546313; PMCID: PMC3158834.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    11. Effect of B-cell depletion using anti-CD20 therapy on inhibitory antibody formation to human FVIII in hemophilia A mice. Blood. 2011 Feb 17; 117(7):2223-6. Zhang AH, Skupsky J, Scott DW. PMID: 21160036; PMCID: PMC3062330.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    12. Disseminated superficial actinic porokeratosis: a treatment review. J Dermatolog Treat. 2012 Feb; 23(1):52-6. Skupsky H, Skupsky J, Goldenberg G. PMID: 20964569.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    13. Gene therapy for tolerance and vice versa: a case for hemophilia. Curr Opin Mol Ther. 2010 Oct; 12(5):509-18. Skupsky J, Saltis M, Song C, Rossi R, Nelson D, Scott DW. PMID: 20886382.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    14. MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity. J Exp Med. 2010 Aug 30; 207(9):1891-905. Irla M, Küpfer N, Suter T, Lissilaa R, Benkhoucha M, Skupsky J, Lalive PH, Fontana A, Reith W, Hugues S. PMID: 20696698; PMCID: PMC2931160.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    15. B-cell delivered gene therapy for tolerance induction: role of autoantigen-specific B cells. J Autoimmun. 2010 Sep; 35(2):107-13. Zhang AH, Li X, Onabajo OO, Su Y, Skupsky J, Thomas JW, Scott DW. PMID: 20579844; PMCID: PMC2926203.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    16. B-cell-delivered gene therapy induces functional T regulatory cells and leads to a loss of antigen-specific effector cells. Mol Ther. 2010 Aug; 18(8):1527-35. Skupsky J, Zhang AH, Su Y, Scott DW. PMID: 20485267; PMCID: PMC2927073.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    17. Factor VIII inhibitors: risk factors and methods for prevention and immune modulation. Clin Rev Allergy Immunol. 2009 Oct; 37(2):114-24. Zhang AH, Skupsky J, Scott DW. PMID: 19199081.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    18. A role for thrombin in the initiation of the immune response to therapeutic factor VIII. Blood. 2009 Nov 19; 114(21):4741-8. Skupsky J, Zhang AH, Su Y, Scott DW. PMID: 19794141; PMCID: PMC2780310.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    19. Tolerance induction by gene transfer to lymphocytes. Curr Gene Ther. 2007 Oct; 7(5):369-80. Skupsky J, Su Y, Lei TC, Scott DW. PMID: 17979683.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    20. Membrane chromatography of DNA: conformation-induced capacity and selectivity. Biotechnol Bioeng. 2004 Oct 05; 88(1):26-34. Haber C, Skupsky J, Lee A, Lander R. PMID: 15384058.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
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