 Medha Pathak
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| Title(s) | Assistant Professor, Physiology and Biophysics |
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| Phone | (949) 824-6623 |
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| vCard | Download vCard |
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 Bibliographic
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Ellefsen KL, Holt JR, Chang AC, Nourse JL, Arulmoli J, Mekhdjian AH, Abuwarda H, Tombola F, Flanagan LA, Dunn AR, Parker I, Pathak MM. Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca2+ flickers. Commun Biol. 2019; 2:298. PMID: 31396578.
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Zhao C, Sun Q, Tang L, Cao Y, Nourse JL, Pathak MM, Lu X, Yang Q. Mechanosensitive Ion Channel Piezo1 Regulates Diet-Induced Adipose Inflammation and Systemic Insulin Resistance. Front Endocrinol (Lausanne). 2019; 10:373. PMID: 31263454.
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Nourse JL, Pathak MM. How cells channel their stress: Interplay between Piezo1 and the cytoskeleton. Semin Cell Dev Biol. 2017 11; 71:3-12. PMID: 28676421.
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Pathak MM, Tran T, Hong L, Joós B, Morris CE, Tombola F. The Hv1 proton channel responds to mechanical stimuli. J Gen Physiol. 2016 11; 148(5):405-418. PMID: 27799320.
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Arulmoli J, Wright HJ, Phan DTT, Sheth U, Que RA, Botten GA, Keating M, Botvinick EL, Pathak MM, Zarembinski TI, Yanni DS, Razorenova OV, Hughes CCW, Flanagan LA. Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering. Acta Biomater. 2016 10 01; 43:122-138. PMID: 27475528.
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Phan L, Kautz R, Arulmoli J, Kim IH, Le DT, Shenk MA, Pathak MM, Flanagan LA, Tombola F, Gorodetsky AA. Reflectin as a Material for Neural Stem Cell Growth. ACS Appl Mater Interfaces. 2016 Jan 13; 8(1):278-84. PMID: 26703760.
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Arulmoli J, Pathak MM, McDonnell LP, Nourse JL, Tombola F, Earthman JC, Flanagan LA. Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner. Sci Rep. 2015 Feb 17; 5:8499. PMID: 25686615.
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Pathak MM, Nourse JL, Tran T, Hwe J, Arulmoli J, Le DT, Bernardis E, Flanagan LA, Tombola F. Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells. Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45):16148-53. PMID: 25349416.
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Kim IH, Hevezi P, Varga C, Pathak MM, Hong L, Ta D, Tran CT, Zlotnik A, Soltesz I, Tombola F. Evidence for functional diversity between the voltage-gated proton channel Hv1 and its closest related protein HVRP1. PLoS One. 2014; 9(8):e105926. PMID: 25165868.
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Nourse JL, Prieto JL, Dickson AR, Lu J, Pathak MM, Tombola F, Demetriou M, Lee AP, Flanagan LA. Membrane biophysics define neuron and astrocyte progenitors in the neural lineage. Stem Cells. 2014 Mar; 32(3):706-16. PMID: 24105912.
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Hong L, Pathak MM, Kim IH, Ta D, Tombola F. Voltage-sensing domain of voltage-gated proton channel Hv1 shares mechanism of block with pore domains. Neuron. 2013 Jan 23; 77(2):274-87. PMID: 23352164.
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Pathak MM, Yarov-Yarovoy V, Agarwal G, Roux B, Barth P, Kohout S, Tombola F, Isacoff EY. Closing in on the resting state of the Shaker K(+) channel. Neuron. 2007 Oct 04; 56(1):124-40. PMID: 17920020.
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Tombola F, Pathak MM, Gorostiza P, Isacoff EY. The twisted ion-permeation pathway of a resting voltage-sensing domain. Nature. 2007 Feb 01; 445(7127):546-9. PMID: 17187057.
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Tombola F, Pathak MM, Isacoff EY. How does voltage open an ion channel? Annu Rev Cell Dev Biol. 2006; 22:23-52. PMID: 16704338.
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Tombola F, Pathak MM, Isacoff EY. How far will you go to sense voltage? Neuron. 2005 Dec 08; 48(5):719-25. PMID: 16337910.
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Tombola F, Pathak MM, Isacoff EY. Voltage-sensing arginines in a potassium channel permeate and occlude cation-selective pores. Neuron. 2005 Feb 03; 45(3):379-88. PMID: 15694325.
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Pathak M, Kurtz L, Tombola F, Isacoff E. The cooperative voltage sensor motion that gates a potassium channel. J Gen Physiol. 2005 Jan; 125(1):57-69. PMID: 15623895.
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