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Agrawal, Anshu

TitleAssociate Professor In Residence
InstitutionUniversity of California, Irvine
DepartmentMedicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-7706
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Rahmatpanah F, Agrawal S, Jaiswal N, Ngyuen HM, McClelland M, Agrawal A. Airway epithelial cells prime plasmacytoid dendritic cells to respond to pathogens via secretion of growth factors. Mucosal Immunol. 2018 Oct 02. PMID: 30279511.
      View in: PubMed
    2. Ghoneum MH, Gimzewski JK, Ghoneum A, Katano H, Paw U CN, Agrawal A. Inhibition of TRPV1 Channel Activity in Human CD4? T Cells by Nanodiamond and Nanoplatinum Liquid, DPV576. Nanomaterials (Basel). 2018 Sep 29; 8(10). PMID: 30274279.
      View in: PubMed
    3. Agrawal S, Abud EM, Snigdha S, Agrawal A. IgM response against amyloid-beta in aging: a potential peripheral protective mechanism. Alzheimers Res Ther. 2018 Aug 16; 10(1):81. PMID: 30115117.
      View in: PubMed
    4. Rahmatpanah F, Agrawal S, Scarfone VM, Kapadia S, Mercola D, Agrawal A. Transcriptional Profiling of Age-Associated Gene Expression Changes in Human Circulatory CD1c+ Myeloid Dendritic Cell Subset. J Gerontol A Biol Sci Med Sci. 2018 Apr 28. PMID: 29718193.
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    5. Elahi A, Sabui S, Narasappa NN, Agrawal S, Lambrecht NW, Agrawal A, Said HM. Biotin Deficiency Induces Th1- and Th17-Mediated Proinflammatory Responses in Human CD4+ T Lymphocytes via Activation of the mTOR Signaling Pathway. J Immunol. 2018 Apr 15; 200(8):2563-2570. PMID: 29531163.
      View in: PubMed
    6. Ferreira TB, Hygino J, Wing AC, Kasahara TM, Sacramento PM, Camargo S, Rueda F, Alves-Leon SV, Alvarenga R, Vasconcelos CC, Agrawal A, Gupta S, Bento CAM. Different interleukin-17-secreting Toll-like receptor+ T-cell subsets are associated with disease activity in multiple sclerosis. Immunology. 2017 Nov 23. PMID: 29168181.
      View in: PubMed
    7. Agrawal A, Agrawal S, Gupta S. Role of Dendritic Cells in Inflammation and Loss of Tolerance in the Elderly. Front Immunol. 2017; 8:896. PMID: 28798751.
      View in: PubMed
    8. Agrawal A. Dendritic Cell-Airway Epithelial Cell Cross-Talk Changes with Age and Contributes to Chronic Lung Inflammatory Diseases in the Elderly. Int J Mol Sci. 2017 Jun 06; 18(6). PMID: 28587289.
      View in: PubMed
    9. Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, Gylys KH, Cahalan MD, Cummings BJ, Antel JP, Mortazavi A, Carson MJ, Poon WW, Blurton-Jones M. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 2017 Apr 19; 94(2):278-293.e9. PMID: 28426964.
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    10. Ghoneum MH, Katano H, Agrawal S, Ganguly S, Agrawal A. Effect of Nanodiamond and Nanoplatinum Liquid, DPV576, on Human Primary Keratinocytes. J Biomed Nanotechnol. 2017 Jan; 13(1):110-16. PMID: 29373005.
      View in: PubMed
    11. Agrawal S, Agrawal A, Said HM. Biotin deficiency enhances the inflammatory response of human dendritic cells. Am J Physiol Cell Physiol. 2016 Sep 01; 311(3):C386-91. PMID: 27413170.
      View in: PubMed
    12. Agrawal S, Ganguly S, Tran A, Sundaram P, Agrawal A. Retinoic acid treated human dendritic cells induce T regulatory cells via the expression of CD141 and GARP which is impaired with age. Aging (Albany NY). 2016 Jun; 8(6):1223-35. PMID: 27244900; PMCID: PMC4931828.
    13. Agrawal S, Ganguly S, Hajian P, Cao JN, Agrawal A. PDGF upregulates CLEC-2 to induce T regulatory cells. Oncotarget. 2015 Oct 06; 6(30):28621-32. PMID: 26416420; PMCID: PMC4745681.
    14. Ghoneum M, Felo N, Agrawal S, Agrawal A. A novel kefir product (PFT) activates dendritic cells to induce CD4+T and CD8+T cell responses in vitro. Int J Immunopathol Pharmacol. 2015 Dec; 28(4):488-96. PMID: 26384392.
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    15. Farid M, Agrawal A, Fremgen D, Tao J, Chuyi H, Nesburn AB, BenMohamed L. Age-related Defects in Ocular and Nasal Mucosal Immune System and the Immunopathology of Dry Eye Disease. Ocul Immunol Inflamm. 2016 Jun; 24(3):327-47. PMID: 25535823; PMCID: PMC4478284.
    16. Cao JN, Agrawal A, Sharman E, Jia Z, Gupta S. Alterations in gene array patterns in dendritic cells from aged humans. PLoS One. 2014; 9(9):e106471. PMID: 25191744; PMCID: PMC4156347.
    17. Prakash S, Agrawal S, Ma D, Gupta S, Peterson EM, Agrawal A. Dendritic cells from aged subjects display enhanced inflammatory responses to Chlamydophila pneumoniae. Mediators Inflamm. 2014; 2014:436438. PMID: 25253920; PMCID: PMC4165882.
    18. Aref AM, Hoa NT, Ge L, Agrawal A, Dacosta-Iyer M, Lambrecht N, Ouyang Y, Cornforth AN, Jadus MR. HCA519/TPX2: a potential T-cell tumor-associated antigen for human hepatocellular carcinoma. Onco Targets Ther. 2014; 7:1061-70. PMID: 24966688; PMCID: PMC4063820.
    19. Gupta S, Agrawal A. Inflammation & autoimmunity in human ageing: dendritic cells take a center stage. Indian J Med Res. 2013 Nov; 138(5):711-6. PMID: 24434323; PMCID: PMC3928701.
    20. Agrawal S, Gollapudi S, Gupta S, Agrawal A. Dendritic cells from the elderly display an intrinsic defect in the production of IL-10 in response to lithium chloride. Exp Gerontol. 2013 Nov; 48(11):1285-92. PMID: 23988651.
      View in: PubMed
    21. Agrawal A. Mechanisms and implications of age-associated impaired innate interferon secretion by dendritic cells: a mini-review. Gerontology. 2013; 59(5):421-6. PMID: 23615484.
      View in: PubMed
    22. Prakash S, Agrawal S, Cao JN, Gupta S, Agrawal A. Impaired secretion of interferons by dendritic cells from aged subjects to influenza : role of histone modifications. Age (Dordr). 2013 Oct; 35(5):1785-97. PMID: 23007963; PMCID: PMC3776111.
    23. Agrawal A, Su H, Chen J, Osann K, Agrawal S, Gupta S. Increased IL-21 secretion by aged CD4+T cells is associated with prolonged STAT-4 activation and CMV seropositivity. Aging (Albany NY). 2012 Sep; 4(9):648-59. PMID: 23064011; PMCID: PMC3492228.
    24. Agrawal A, Sridharan A, Prakash S, Agrawal H. Dendritic cells and aging: consequences for autoimmunity. Expert Rev Clin Immunol. 2012 Jan; 8(1):73-80. PMID: 22149342; PMCID: PMC3285507.
    25. Agrawal S, Gupta S, Agrawal A. Human dendritic cells activated via dectin-1 are efficient at priming Th17, cytotoxic CD8 T and B cell responses. PLoS One. 2010 Oct 18; 5(10):e13418. PMID: 20976143; PMCID: PMC2956651.
    26. Sridharan A, Esposo M, Kaushal K, Tay J, Osann K, Agrawal S, Gupta S, Agrawal A. Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity. Age (Dordr). 2011 Sep; 33(3):363-76. PMID: 20953722; PMCID: PMC3168606.
    27. Agrawal A, Gupta S. Impact of aging on dendritic cell functions in humans. Ageing Res Rev. 2011 Jul; 10(3):336-45. PMID: 20619360; PMCID: PMC3030666.
    28. Agrawal A, Tay J, Yang GE, Agrawal S, Gupta S. Age-associated epigenetic modifications in human DNA increase its immunogenicity. Aging (Albany NY). 2010 Mar 20; 2(2):93-100. PMID: 20354270; PMCID: PMC2850145.
    29. Agrawal A. Altered expression of NFkappaB in ex vivo differentiated dendritic cells from the aged subjects: implications in immunotherapy. Methods Mol Biol. 2010; 621:175-83. PMID: 20405367.
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    30. Carlson ME, Conboy MJ, Hsu M, Barchas L, Jeong J, Agrawal A, Mikels AJ, Agrawal S, Schaffer DV, Conboy IM. Relative roles of TGF-beta1 and Wnt in the systemic regulation and aging of satellite cell responses. Aging Cell. 2009 Dec; 8(6):676-89. PMID: 19732043; PMCID: PMC2783265.
    31. Gu B, Sun P, Yuan Y, Moraes RC, Li A, Teng A, Agrawal A, Rhéaume C, Bilanchone V, Veltmaat JM, Takemaru K, Millar S, Lee EY, Lewis MT, Li B, Dai X. Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol. 2009 Jun 01; 185(5):811-26. PMID: 19487454; PMCID: PMC2711593.
    32. Agrawal A, Tay J, Ton S, Agrawal S, Gupta S. Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA. J Immunol. 2009 Jan 15; 182(2):1138-45. PMID: 19124757; PMCID: PMC2621318.
    33. Agrawal S, Gupta S, Agrawal A. Vaccinia virus proteins activate human dendritic cells to induce T cell responses in vitro. Vaccine. 2009 Jan 01; 27(1):88-92. PMID: 18977270.
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    34. Agrawal A, Lourenço EV, Gupta S, La Cava A. Gender-Based Differences in Leptinemia in Healthy Aging, Non-obese Individuals Associate with Increased Marker of Oxidative Stress. Int J Clin Exp Med. 2008; 1(4):305-9. PMID: 19079674; PMCID: PMC2596325.
    35. Agrawal A, Agrawal S, Tay J, Gupta S. Biology of dendritic cells in aging. J Clin Immunol. 2008 Jan; 28(1):14-20. PMID: 17828583.
      View in: PubMed
    36. Agrawal A, Agrawal S, Cao JN, Su H, Osann K, Gupta S. Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway. J Immunol. 2007 Jun 01; 178(11):6912-22. PMID: 17513740.
      View in: PubMed
    37. Agrawal A, Agrawal S, Gupta S. Dendritic cells in human aging. Exp Gerontol. 2007 May; 42(5):421-6. PMID: 17182207; PMCID: PMC1909691.
    38. Agrawal A, Kaushal P, Agrawal S, Gollapudi S, Gupta S. Thimerosal induces TH2 responses via influencing cytokine secretion by human dendritic cells. J Leukoc Biol. 2007 Feb; 81(2):474-82. PMID: 17079650.
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    39. Agrawal A, Yang J, Murphy RF, Agrawal DK. Regulation of the p14ARF-Mdm2-p53 pathway: an overview in breast cancer. Exp Mol Pathol. 2006 Oct; 81(2):115-22. PMID: 16919268.
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    40. Gupta S, Agrawal A, Agrawal S, Su H, Gollapudi S. A paradox of immunodeficiency and inflammation in human aging: lessons learned from apoptosis. Immun Ageing. 2006 May 19; 3:5. PMID: 16712718; PMCID: PMC1475884.
    41. Agrawal A, Dillon S, Denning TL, Pulendran B. ERK1-/- mice exhibit Th1 cell polarization and increased susceptibility to experimental autoimmune encephalomyelitis. J Immunol. 2006 May 15; 176(10):5788-96. PMID: 16670284.
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    42. Nair M, Teng A, Bilanchone V, Agrawal A, Li B, Dai X. Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcription. J Cell Biol. 2006 Apr 24; 173(2):253-64. PMID: 16636146; PMCID: PMC2063816.
    43. Andrianifahanana M, Agrawal A, Singh AP, Moniaux N, van Seuningen I, Aubert JP, Meza J, Batra SK. Synergistic induction of the MUC4 mucin gene by interferon-gamma and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways. Oncogene. 2005 Sep 08; 24(40):6143-54. PMID: 16007204.
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    44. Dillon S, Agrawal A, Van Dyke T, Landreth G, McCauley L, Koh A, Maliszewski C, Akira S, Pulendran B. A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells. J Immunol. 2004 Apr 15; 172(8):4733-43. PMID: 15067049.
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    45. Agrawal S, Agrawal A, Doughty B, Gerwitz A, Blenis J, Van Dyke T, Pulendran B. Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. J Immunol. 2003 Nov 15; 171(10):4984-9. PMID: 14607893.
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    46. Agrawal A, Lingappa J, Leppla SH, Agrawal S, Jabbar A, Quinn C, Pulendran B. Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin. Nature. 2003 Jul 17; 424(6946):329-34. PMID: 12867985.
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