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Anshu Agrawal

Title(s)Professor In Residence, Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-7706
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nicotine Impairs the Response of Lung Epithelial Cells to IL-22. Mediators Inflamm. 2020; 2020:6705428. Nguyen HM, Torres JA, Agrawal S, Agrawal A. PMID: 32189996.
      View in: PubMed   Mentions:    Fields:    
    2. Immune and Inflammatory Determinants Underlying Alzheimer's Disease Pathology. J Neuroimmune Pharmacol. 2020 Feb 24. Baulch JE, Acharya MM, Agrawal S, Apodaca LA, Monteiro C, Agrawal A. PMID: 32090272.
      View in: PubMed   Mentions:    Fields:    
    3. Tamoxifen-induced, intestinal-specific deletion of Slc5a6 in adult mice leads to spontaneous inflammation: involvement of NF-?B, NLRP3, and gut microbiota. Am J Physiol Gastrointest Liver Physiol. 2019 10 01; 317(4):G518-G530. Sabui S, Skupsky J, Kapadia R, Cogburn K, Lambrecht NW, Agrawal A, Said HM. PMID: 31369292.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. Serum leptin levels correlate negatively with the capacity of vitamin D to modulate the in vitro cytokines production by CD4+ T cells in asthmatic patients. Clin Immunol. 2019 08; 205:93-105. Dias ASO, Santos ICL, Delphim L, Fernandes G, Endlich LR, Cafasso MOSD, Maranhão AL, da Silva SR, Andrade RM, Agrawal A, Linhares UC, Bento CAM. PMID: 31173888.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Correction: Airway epithelial cells prime plasmacytoid dendritic cells to respond to pathogens via secretion of growth factors. Mucosal Immunol. 2019 05; 12(3):841. Rahmatpanah F, Agrawal S, Jaiswal N, Nguyen HM, McClelland M, Agrawal A. PMID: 30705377.
      View in: PubMed   Mentions:    Fields:    
    6. Unique Type I Interferon, Expansion/Survival Cytokines, and JAK/STAT Gene Signatures of Multifunctional Herpes Simplex Virus-Specific Effector Memory CD8+ TEM Cells Are Associated with Asymptomatic Herpes in Humans. J Virol. 2019 02 15; 93(4). Vahed H, Agrawal A, Srivastava R, Prakash S, Coulon PA, Roy S, BenMohamed L. PMID: 30487281.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsPHPublic Health
    7. Transcriptional Profiling of Age-Associated Gene Expression Changes in Human Circulatory CD1c+ Myeloid Dendritic Cell Subset. J Gerontol A Biol Sci Med Sci. 2019 01 01; 74(1):9-15. Rahmatpanah F, Agrawal S, Scarfone VM, Kapadia S, Mercola D, Agrawal A. PMID: 29718193.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    8. Airway epithelial cells prime plasmacytoid dendritic cells to respond to pathogens via secretion of growth factors. Mucosal Immunol. 2019 01; 12(1):77-84. Rahmatpanah F, Agrawal S, Jaiswal N, Nguyen HM, McClelland M, Agrawal A. PMID: 30279511.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. Inhibition of TRPV1 Channel Activity in Human CD4? T Cells by Nanodiamond and Nanoplatinum Liquid, DPV576. Nanomaterials (Basel). 2018 Sep 29; 8(10). Ghoneum MH, Gimzewski JK, Ghoneum A, Katano H, Paw U CN, Agrawal A. PMID: 30274279.
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    10. IgM response against amyloid-beta in aging: a potential peripheral protective mechanism. Alzheimers Res Ther. 2018 08 16; 10(1):81. Agrawal S, Abud EM, Snigdha S, Agrawal A. PMID: 30115117.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    11. Biotin Deficiency Induces Th1- and Th17-Mediated Proinflammatory Responses in Human CD4+ T Lymphocytes via Activation of the mTOR Signaling Pathway. J Immunol. 2018 04 15; 200(8):2563-2570. Elahi A, Sabui S, Narasappa NN, Agrawal S, Lambrecht NW, Agrawal A, Said HM. PMID: 29531163.
      View in: PubMed   Mentions: 2     Fields:    
    12. Different interleukin-17-secreting Toll-like receptor+ T-cell subsets are associated with disease activity in multiple sclerosis. Immunology. 2018 06; 154(2):239-252. Ferreira TB, Hygino J, Wing AC, Kasahara TM, Sacramento PM, Camargo S, Rueda F, Alves-Leon SV, Alvarenga R, Vasconcelos CC, Agrawal A, Gupta S, Bento CAM. PMID: 29168181.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Role of Dendritic Cells in Inflammation and Loss of Tolerance in the Elderly. Front Immunol. 2017; 8:896. Agrawal A, Agrawal S, Gupta S. PMID: 28798751.
      View in: PubMed   Mentions: 6     Fields:    
    14. Dendritic Cell-Airway Epithelial Cell Cross-Talk Changes with Age and Contributes to Chronic Lung Inflammatory Diseases in the Elderly. Int J Mol Sci. 2017 Jun 06; 18(6). Agrawal A. PMID: 28587289.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    15. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 2017 Apr 19; 94(2):278-293.e9. Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, Gylys KH, Cahalan MD, Cummings BJ, Antel JP, Mortazavi A, Carson MJ, Poon WW, Blurton-Jones M. PMID: 28426964.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    16. Effect of Nanodiamond and Nanoplatinum Liquid, DPV576, on Human Primary Keratinocytes. J Biomed Nanotechnol. 2017 Jan; 13(1):110-16. Ghoneum MH, Katano H, Agrawal S, Ganguly S, Agrawal A. PMID: 29373005.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    17. Biotin deficiency enhances the inflammatory response of human dendritic cells. Am J Physiol Cell Physiol. 2016 09 01; 311(3):C386-91. Agrawal S, Agrawal A, Said HM. PMID: 27413170.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    18. Retinoic acid treated human dendritic cells induce T regulatory cells via the expression of CD141 and GARP which is impaired with age. Aging (Albany NY). 2016 06; 8(6):1223-35. Agrawal S, Ganguly S, Tran A, Sundaram P, Agrawal A. PMID: 27244900.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    19. PDGF upregulates CLEC-2 to induce T regulatory cells. Oncotarget. 2015 Oct 06; 6(30):28621-32. Agrawal S, Ganguly S, Hajian P, Cao JN, Agrawal A. PMID: 26416420.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    20. A novel kefir product (PFT) activates dendritic cells to induce CD4+T and CD8+T cell responses in vitro. Int J Immunopathol Pharmacol. 2015 Dec; 28(4):488-96. Ghoneum M, Felo N, Agrawal S, Agrawal A. PMID: 26384392.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    21. Age-related Defects in Ocular and Nasal Mucosal Immune System and the Immunopathology of Dry Eye Disease. Ocul Immunol Inflamm. 2016 Jun; 24(3):327-47. Farid M, Agrawal A, Fremgen D, Tao J, Chuyi H, Nesburn AB, BenMohamed L. PMID: 25535823.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    22. Alterations in gene array patterns in dendritic cells from aged humans. PLoS One. 2014; 9(9):e106471. Cao JN, Agrawal A, Sharman E, Jia Z, Gupta S. PMID: 25191744.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    23. Dendritic cells from aged subjects display enhanced inflammatory responses to Chlamydophila pneumoniae. Mediators Inflamm. 2014; 2014:436438. Prakash S, Agrawal S, Ma D, Gupta S, Peterson EM, Agrawal A. PMID: 25253920.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    24. HCA519/TPX2: a potential T-cell tumor-associated antigen for human hepatocellular carcinoma. Onco Targets Ther. 2014; 7:1061-70. Aref AM, Hoa NT, Ge L, Agrawal A, Dacosta-Iyer M, Lambrecht N, Ouyang Y, Cornforth AN, Jadus MR. PMID: 24966688.
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    25. Inflammation & autoimmunity in human ageing: dendritic cells take a center stage. Indian J Med Res. 2013 Nov; 138(5):711-6. Gupta S, Agrawal A. PMID: 24434323.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    26. Dendritic cells from the elderly display an intrinsic defect in the production of IL-10 in response to lithium chloride. Exp Gerontol. 2013 Nov; 48(11):1285-92. Agrawal S, Gollapudi S, Gupta S, Agrawal A. PMID: 23988651.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    27. Mechanisms and implications of age-associated impaired innate interferon secretion by dendritic cells: a mini-review. Gerontology. 2013; 59(5):421-6. Agrawal A. PMID: 23615484.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    28. Impaired secretion of interferons by dendritic cells from aged subjects to influenza : role of histone modifications. Age (Dordr). 2013 Oct; 35(5):1785-97. Prakash S, Agrawal S, Cao JN, Gupta S, Agrawal A. PMID: 23007963.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    29. Increased IL-21 secretion by aged CD4+T cells is associated with prolonged STAT-4 activation and CMV seropositivity. Aging (Albany NY). 2012 Sep; 4(9):648-59. Agrawal A, Su H, Chen J, Osann K, Agrawal S, Gupta S. PMID: 23064011.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    30. Dendritic cells and aging: consequences for autoimmunity. Expert Rev Clin Immunol. 2012 Jan; 8(1):73-80. Agrawal A, Sridharan A, Prakash S, Agrawal H. PMID: 22149342.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    31. Human dendritic cells activated via dectin-1 are efficient at priming Th17, cytotoxic CD8 T and B cell responses. PLoS One. 2010 Oct 18; 5(10):e13418. Agrawal S, Gupta S, Agrawal A. PMID: 20976143.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    32. Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity. Age (Dordr). 2011 Sep; 33(3):363-76. Sridharan A, Esposo M, Kaushal K, Tay J, Osann K, Agrawal S, Gupta S, Agrawal A. PMID: 20953722.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    33. Impact of aging on dendritic cell functions in humans. Ageing Res Rev. 2011 Jul; 10(3):336-45. Agrawal A, Gupta S. PMID: 20619360.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    34. Age-associated epigenetic modifications in human DNA increase its immunogenicity. Aging (Albany NY). 2010 Mar 20; 2(2):93-100. Agrawal A, Tay J, Yang GE, Agrawal S, Gupta S. PMID: 20354270.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    35. Altered expression of NFkappaB in ex vivo differentiated dendritic cells from the aged subjects: implications in immunotherapy. Methods Mol Biol. 2010; 621:175-83. Agrawal A. PMID: 20405367.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    36. Relative roles of TGF-beta1 and Wnt in the systemic regulation and aging of satellite cell responses. Aging Cell. 2009 Dec; 8(6):676-89. Carlson ME, Conboy MJ, Hsu M, Barchas L, Jeong J, Agrawal A, Mikels AJ, Agrawal S, Schaffer DV, Conboy IM. PMID: 19732043.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    37. Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol. 2009 Jun 01; 185(5):811-26. Gu B, Sun P, Yuan Y, Moraes RC, Li A, Teng A, Agrawal A, Rhéaume C, Bilanchone V, Veltmaat JM, Takemaru K, Millar S, Lee EY, Lewis MT, Li B, Dai X. PMID: 19487454.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    38. Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA. J Immunol. 2009 Jan 15; 182(2):1138-45. Agrawal A, Tay J, Ton S, Agrawal S, Gupta S. PMID: 19124757.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    39. Vaccinia virus proteins activate human dendritic cells to induce T cell responses in vitro. Vaccine. 2009 Jan 01; 27(1):88-92. Agrawal S, Gupta S, Agrawal A. PMID: 18977270.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    40. Gender-Based Differences in Leptinemia in Healthy Aging, Non-obese Individuals Associate with Increased Marker of Oxidative Stress. Int J Clin Exp Med. 2008; 1(4):305-9. Agrawal A, Lourenço EV, Gupta S, La Cava A. PMID: 19079674.
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    41. Biology of dendritic cells in aging. J Clin Immunol. 2008 Jan; 28(1):14-20. Agrawal A, Agrawal S, Tay J, Gupta S. PMID: 17828583.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    42. Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway. J Immunol. 2007 Jun 01; 178(11):6912-22. Agrawal A, Agrawal S, Cao JN, Su H, Osann K, Gupta S. PMID: 17513740.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansCells
    43. Dendritic cells in human aging. Exp Gerontol. 2007 May; 42(5):421-6. Agrawal A, Agrawal S, Gupta S. PMID: 17182207.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    44. Thimerosal induces TH2 responses via influencing cytokine secretion by human dendritic cells. J Leukoc Biol. 2007 Feb; 81(2):474-82. Agrawal A, Kaushal P, Agrawal S, Gollapudi S, Gupta S. PMID: 17079650.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    45. Regulation of the p14ARF-Mdm2-p53 pathway: an overview in breast cancer. Exp Mol Pathol. 2006 Oct; 81(2):115-22. Agrawal A, Yang J, Murphy RF, Agrawal DK. PMID: 16919268.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    46. A paradox of immunodeficiency and inflammation in human aging: lessons learned from apoptosis. Immun Ageing. 2006 May 19; 3:5. Gupta S, Agrawal A, Agrawal S, Su H, Gollapudi S. PMID: 16712718.
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    47. ERK1-/- mice exhibit Th1 cell polarization and increased susceptibility to experimental autoimmune encephalomyelitis. J Immunol. 2006 May 15; 176(10):5788-96. Agrawal A, Dillon S, Denning TL, Pulendran B. PMID: 16670284.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    48. Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcription. J Cell Biol. 2006 Apr 24; 173(2):253-64. Nair M, Teng A, Bilanchone V, Agrawal A, Li B, Dai X. PMID: 16636146.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    49. Synergistic induction of the MUC4 mucin gene by interferon-gamma and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways. Oncogene. 2005 Sep 08; 24(40):6143-54. Andrianifahanana M, Agrawal A, Singh AP, Moniaux N, van Seuningen I, Aubert JP, Meza J, Batra SK. PMID: 16007204.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    50. A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells. J Immunol. 2004 Apr 15; 172(8):4733-43. Dillon S, Agrawal A, Van Dyke T, Landreth G, McCauley L, Koh A, Maliszewski C, Akira S, Pulendran B. PMID: 15067049.
      View in: PubMed   Mentions: 152     Fields:    Translation:AnimalsCells
    51. Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. J Immunol. 2003 Nov 15; 171(10):4984-9. Agrawal S, Agrawal A, Doughty B, Gerwitz A, Blenis J, Van Dyke T, Pulendran B. PMID: 14607893.
      View in: PubMed   Mentions: 234     Fields:    Translation:HumansCells
    52. Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin. Nature. 2003 Jul 17; 424(6946):329-34. Agrawal A, Lingappa J, Leppla SH, Agrawal S, Jabbar A, Quinn C, Pulendran B. PMID: 12867985.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansAnimalsCells
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