George A Gutman

Title(s)Professor Emeritus, Microbiology and Molecular Genetics
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-6593, 6370
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    SHORT-TERM TRAINING STUDENTS IN HEALTH PROFESSIONAL SCHO
    NIH T35GM008630Aug 1, 1997 - Apr 30, 2002
    Role: Principal Investigator
    STRUCTURE AND EXPRESSION OF IMMUNOGLOBULIN LAMBDA CHAIN
    NIH R01AI021366Apr 1, 1986 - Jul 31, 1989
    Role: Principal Investigator
    STRUCTURE AND GENE ORGANIZATION OF RAT KAPPA CHAINS
    NIH R01AI014774Apr 1, 1978 - Jun 30, 1986
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases. FASEB J. 2014 Sep; 28(9):3952-64. Chhabra S, Chang SC, Nguyen HM, Huq R, Tanner MR, Londono LM, Estrada R, Dhawan V, Chauhan S, Upadhyay SK, Gindin M, Hotez PJ, Valenzuela JG, Mohanty B, Swarbrick JD, Wulff H, Iadonato SP, Gutman GA, Beeton C, Pennington MW, Norton RS, Chandy KG. PMID: 24891519.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    2. IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels. Nucleic Acids Res. 2009 Jan; 37(Database issue):D680-5. Harmar AJ, Hills RA, Rosser EM, Jones M, Buneman OP, Dunbar DR, Greenhill SD, Hale VA, Sharman JL, Bonner TI, Catterall WA, Davenport AP, Delagrange P, Dollery CT, Foord SM, Gutman GA, Laudet V, Neubig RR, Ohlstein EH, Olsen RW, Peters J, Pin JP, Ruffolo RR, Searls DB, Wright MW, Spedding M. PMID: 18948278.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimals
    3. Alternative polyadenylation signals in the 3' non-coding region of a voltage-gated potassium channel gene are major determinants of mRNA isoform expression. Gene. 2008 Jan 31; 408(1-2):133-45. Jang GM, Tanaka BS, Gutman GA, Goldin AL, Semler BL. PMID: 18077107.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases. Proc Natl Acad Sci U S A. 2006 Nov 14; 103(46):17414-9. Beeton C, Wulff H, Standifer NE, Azam P, Mullen KM, Pennington MW, Kolski-Andreaco A, Wei E, Grino A, Counts DR, Wang PH, LeeHealey CJ, S Andrews B, Sankaranarayanan A, Homerick D, Roeck WW, Tehranzadeh J, Stanhope KL, Zimin P, Havel PJ, Griffey S, Knaus HG, Nepom GT, Gutman GA, Calabresi PA, Chandy KG. PMID: 17088564.
      View in: PubMed   Mentions: 200     Fields:    Translation:HumansAnimalsCells
    5. The sense of place in the immune system. Nat Immunol. 2006 Apr; 7(4):329-32. Cahalan MD, Gutman GA. PMID: 16550194.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    6. Overview of molecular relationships in the voltage-gated ion channel superfamily. Pharmacol Rev. 2005 Dec; 57(4):387-95. Yu FH, Yarov-Yarovoy V, Gutman GA, Catterall WA. PMID: 16382097.
      View in: PubMed   Mentions: 172     Fields:    Translation:HumansAnimalsCells
    7. International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels. Pharmacol Rev. 2005 Dec; 57(4):463-72. Wei AD, Gutman GA, Aldrich R, Chandy KG, Grissmer S, Wulff H. PMID: 16382103.
      View in: PubMed   Mentions: 150     Fields:    Translation:HumansAnimals
    8. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacol Rev. 2005 Dec; 57(4):473-508. Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stühmer W, Wang X. PMID: 16382104.
      View in: PubMed   Mentions: 304     Fields:    Translation:HumansAnimals
    9. Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases. Mol Pharmacol. 2005 Apr; 67(4):1369-81. Beeton C, Pennington MW, Wulff H, Singh S, Nugent D, Crossley G, Khaytin I, Calabresi PA, Chen CY, Gutman GA, Chandy KG. PMID: 15665253.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    10. Structurally distinct elements mediate internal ribosome entry within the 5'-noncoding region of a voltage-gated potassium channel mRNA. J Biol Chem. 2004 Nov 12; 279(46):47419-30. Jang GM, Leong LE, Hoang LT, Wang PH, Gutman GA, Semler BL. PMID: 15339906.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    11. K+ channels as targets for specific immunomodulation. Trends Pharmacol Sci. 2004 May; 25(5):280-9. Chandy KG, Wulff H, Beeton C, Pennington M, Gutman GA, Cahalan MD. PMID: 15120495.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansCells
    12. Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia. J Clin Invest. 2004 Feb; 113(4):582-90. Shakkottai VG, Chou CH, Oddo S, Sailer CA, Knaus HG, Gutman GA, Barish ME, LaFerla FM, Chandy KG. PMID: 14966567.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    13. International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacol Rev. 2003 Dec; 55(4):583-6. Gutman GA, Chandy KG, Adelman JP, Aiyar J, Bayliss DA, Clapham DE, Covarriubias M, Desir GV, Furuichi K, Ganetzky B, Garcia ML, Grissmer S, Jan LY, Karschin A, Kim D, Kuperschmidt S, Kurachi Y, Lazdunski M, Lesage F, Lester HA, McKinnon D, Nichols CG, O'Kelly I, Robbins J, Robertson GA, Rudy B, Sanguinetti M, Seino S, Stuehmer W, Tamkun MM, Vandenberg CA, Wei A, Wulff H, Wymore RS, International Union of Pharmacology . PMID: 14657415.
      View in: PubMed   Mentions: 97     Fields:    
    14. SK3-1C, a dominant-negative suppressor of SKCa and IKCa channels. J Biol Chem. 2004 Feb 20; 279(8):6893-904. Kolski-Andreaco A, Tomita H, Shakkottai VG, Gutman GA, Cahalan MD, Gargus JJ, Chandy KG. PMID: 14638680.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    15. A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes. J Biol Chem. 2003 Mar 14; 278(11):9928-37. Beeton C, Wulff H, Singh S, Botsko S, Crossley G, Gutman GA, Cahalan MD, Pennington M, Chandy KG. PMID: 12511563.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
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