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Yama Akbari

Title(s)Assistant Professor, Neurology
Phone(949) 824-1888
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    Collapse Research 
    Collapse Research Activities and Funding
    Multimodal Optical Imaging of Hyperdynamic Cerebral Responses to Cardiac Arrest and Resuscitation
    NIH/NIBIB R21EB024793Aug 15, 2017 - May 31, 2020
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shuttleworth CW, Andrew RD, Akbari Y, Ayata C, Balu R, Brennan KC, Boutelle M, Carlson AP, Dreier JP, Fabricius M, Farkas E, Foreman B, Helbok R, Henninger N, Jewell SL, Jones SC, Kirov SA, Lindquist BE, Maciel CB, Okonkwo D, Reinhart KM, Robertson RM, Rosenthal ES, Watanabe T, Hartings JA. Which Spreading Depolarizations Are Deleterious To Brain Tissue? Neurocrit Care. 2019 Aug 06. PMID: 31388871.
      View in: PubMed
    2. Yin HZ, Wang HL, Ji SG, Medvedeva YV, Tian G, Bazrafkan AK, Maki NZ, Akbari Y, Weiss JH. Rapid Intramitochondrial Zn2+ Accumulation in CA1 Hippocampal Pyramidal Neurons After Transient Global Ischemia: A Possible Contributor to Mitochondrial Disruption and Cell Death. J Neuropathol Exp Neurol. 2019 Jul 01; 78(7):655-664. PMID: 31150090.
      View in: PubMed
    3. Wilson RH, Crouzet C, Torabzadeh M, Bazrafkan A, Farahabadi MH, Jamasian B, Donga D, Alcocer J, Zaher SM, Choi B, Akbari Y, Tromberg BJ. High-speed spatial frequency domain imaging of rat cortex detects dynamic optical and physiological properties following cardiac arrest and resuscitation. Neurophotonics. 2017 Oct; 4(4):045008. PMID: 29296630.
      View in: PubMed
    4. Kang YJ, Tian G, Bazrafkan A, Farahabadi MH, Azadian M, Abbasi H, Shamaoun BE, Steward O, Akbari Y. Recovery from Coma Post-Cardiac Arrest Is Dependent on the Orexin Pathway. J Neurotrauma. 2017 10 01; 34(19):2823-2832. PMID: 28447885.
      View in: PubMed
    5. Hong D, Stradling D, Dastur CK, Akbari Y, Groysman L, Al-Khoury L, Chen J, Small SL, Yu W. Resistant Hypertension after Hypertensive Intracerebral Hemorrhage Is Associated with More Medical Interventions and Longer Hospital Stays without Affecting Outcome. Front Neurol. 2017; 8:184. PMID: 28515710.
      View in: PubMed
    6. Lee DE, Lee LG, Siu D, Bazrafkan AK, Farahabadi MH, Dinh TJ, Orellana J, Xiong W, Lopour BA, Akbari Y. Neural Correlates of Consciousness at Near-Electrocerebral Silence in an Asphyxial Cardiac Arrest Model. Brain Connect. 2017 04; 7(3):172-181. PMID: 28398813.
      View in: PubMed
    7. Crouzet C, Wilson RH, Bazrafkan A, Farahabadi MH, Lee D, Alcocer J, Tromberg BJ, Choi B, Akbari Y. Cerebral blood flow is decoupled from blood pressure and linked to EEG bursting after resuscitation from cardiac arrest. Biomed Opt Express. 2016 Nov 01; 7(11):4660-4673. PMID: 27896005.
      View in: PubMed
    8. Maybhate A, Chen C, Akbari Y, Sherman DL, Shen K, Jia X, Thakor NV. Band specific changes in thalamocortical synchrony in field potentials after cardiac arrest induced global hypoxia. Conf Proc IEEE Eng Med Biol Soc. 2013; 2013:7112-5. PMID: 24111384.
      View in: PubMed
    9. Akbari Y, Geocadin RG. A new generation of therapeutic hypothermia: using a warm syringe to cool. Crit Care Med. 2011 Nov; 39(11):2558-9. PMID: 22005225.
      View in: PubMed
    10. Green KN, Demuro A, Akbari Y, Hitt BD, Smith IF, Parker I, LaFerla FM. SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. J Gen Physiol. 2008 Aug; 132(2):i1. PMID: 18663130.
      View in: PubMed
    11. Green KN, Demuro A, Akbari Y, Hitt BD, Smith IF, Parker I, LaFerla FM. SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. J Cell Biol. 2008 Jun 30; 181(7):1107-16. PMID: 18591429.
      View in: PubMed
    12. Caccamo A, Oddo S, Sugarman MC, Akbari Y, LaFerla FM. Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders. Neurobiol Aging. 2005 May; 26(5):645-54. PMID: 15708439.
      View in: PubMed
    13. Akbari Y, Hitt BD, Murphy MP, Dagher NN, Tseng BP, Green KN, Golde TE, LaFerla FM. Presenilin regulates capacitative calcium entry dependently and independently of gamma-secretase activity. Biochem Biophys Res Commun. 2004 Oct 01; 322(4):1145-52. PMID: 15336962.
      View in: PubMed
    14. Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron. 2003 Jul 31; 39(3):409-21. PMID: 12895417.
      View in: PubMed
    15. Leissring MA, Murphy MP, Mead TR, Akbari Y, Sugarman MC, Jannatipour M, Anliker B, Müller U, Saftig P, De Strooper B, Wolfe MS, Golde TE, LaFerla FM. A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP. Proc Natl Acad Sci U S A. 2002 Apr 02; 99(7):4697-702. PMID: 11917117.
      View in: PubMed
    16. Leissring MA, Akbari Y, Fanger CM, Cahalan MD, Mattson MP, LaFerla FM. Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice. J Cell Biol. 2000 May 15; 149(4):793-8. PMID: 10811821.
      View in: PubMed