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Hamid M Said

Title(s)Professor, Medicine
Phone(949) 824-0064, 3423
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    Collapse Research 
    Collapse Research Activities and Funding
    Physiological and Pathological Aspects of Intestinal Vitamin B2 Absorption
    VA I01BX001142Apr 1, 2011 - Jun 30, 2020
    Role: Principal Investigator
    Physiology/Pathophysiology of Vitamin B1 Transport in Pancreatic Acinar Cells
    NIH/NIAAA R01AA018071Apr 1, 2009 - Jan 31, 2019
    Role: Principal Investigator
    C elegans:a model to study intestinal water-soluble vitamins transport in vivo
    NIH/NIDDK R21DK075348Sep 8, 2006 - Aug 31, 2009
    Role: Principal Investigator
    Intestinal Biotin Absorption: Physiological and Pathophysiological Aspects
    NIH/NIDDK R01DK058057Sep 15, 2000 - Jul 31, 2020
    Role: Principal Investigator
    Mechanism/Regulation of Intestinal Thiamin Uptake
    NIH/NIDDK R37DK056061Aug 1, 1999 - Jul 31, 2019
    Role: Principal Investigator
    Mechanism/regulation of human intestinal thiamin uptake
    NIH/NIDDK R01DK056061Aug 1, 1999 - Jul 31, 2009
    Role: Principal Investigator
    RIBOFLAVIN TRANSPORT IN RENAL PROXIMAL TUBULES
    NIH/NIDDK R01DK047203Jul 1, 1996 - Apr 30, 2000
    Role: Principal Investigator
    NUTRITIONAL STUDIES ON BIOTON ABSORPTION
    NIH/NIDDK R01DK039501Mar 1, 1988 - Nov 30, 1991
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Skupsky J, Sabui S, Hwang M, Nakasaki M, Cahalan MD, Said HM. Biotin Supplementation Ameliorates Murine Colitis by Preventing NF-?B Activation. Cell Mol Gastroenterol Hepatol. 2019 Nov 29. PMID: 31786364.
      View in: PubMed
    2. Jonus HC, Byrnes CC, Kim J, Valle ML, Bartlett MG, Said HM, Zastre JA. Thiamine mimetics sulbutiamine and benfotiamine as a nutraceutical approach to anticancer therapy. Biomed Pharmacother. 2020 Jan; 121:109648. PMID: 31810115.
      View in: PubMed
    3. Anandam KY, Sabui S, Thompson MM, Subramanian S, Said HM. Enterohemorrhagic Escherichia coli infection inhibits colonic thiamin pyrophosphate uptake via transcriptional mechanism. PLoS One. 2019; 14(10):e0224234. PMID: 31639155.
      View in: PubMed
    4. Bottega R, Perrone MD, Vecchiato K, Taddio A, Sabui S, Pecile V, Said HM, Faletra F. Functional analysis of the third identified SLC25A19 mutation causative for the thiamine metabolism dysfunction syndrome 4. J Hum Genet. 2019 Nov; 64(11):1075-1081. PMID: 31506564.
      View in: PubMed
    5. Srinivasan P, Ramesh V, Wu J, Heskett C, Chu BD, Said HM. Pyridoxine and pancreatic acinar cells: transport physiology and effect on gene expression profile. Am J Physiol Cell Physiol. 2019 Dec 01; 317(6):C1107-C1114. PMID: 31483702.
      View in: PubMed
    6. Sabui S, Skupsky J, Kapadia R, Cogburn K, Lambrecht NW, Agrawal A, Said HM. Tamoxifen-induced, intestinal-specific deletion of Slc5a6 in adult mice leads to spontaneous inflammation: involvement of NF-?B, NLRP3, and gut microbiota. Am J Physiol Gastrointest Liver Physiol. 2019 Oct 01; 317(4):G518-G530. PMID: 31369292.
      View in: PubMed
    7. Srinivasan P, Anandam KY, Ramesh V, Geltz ET, Said HM. Effect of bacterial flagellin on thiamin uptake by human and mouse pancreatic acinar cells: inhibition mediated at the level of transcription of thiamin transporters 1 and 2. Am J Physiol Gastrointest Liver Physiol. 2019 06 01; 316(6):G735-G743. PMID: 30920302.
      View in: PubMed
    8. Sabui S, Subramanian VS, Pham Q, Said HM. Identification of transmembrane protein 237 as a novel interactor with the intestinal riboflavin transporter-3 (RFVT-3): role in functionality and cell biology. Am J Physiol Cell Physiol. 2019 06 01; 316(6):C805-C814. PMID: 30892938.
      View in: PubMed
    9. Subramanian VS, Sabui S, Marchant JS, Said HM. MicroRNA-103a regulates sodium-dependent vitamin C transporter-1 expression in intestinal epithelial cells. J Nutr Biochem. 2019 03; 65:46-53. PMID: 30616065.
      View in: PubMed
    10. Subramenium GA, Sabui S, Marchant JS, Said HM, Subramanian VS. Enterotoxigenic Escherichia coli heat labile enterotoxin inhibits intestinal ascorbic acid uptake via a cAMP-dependent NF-?B-mediated pathway. Am J Physiol Gastrointest Liver Physiol. 2019 01 01; 316(1):G55-G63. PMID: 30285481.
      View in: PubMed
    11. Subramanian VS, Sabui S, Heskett CW, Said HM. Sodium Butyrate Enhances Intestinal Riboflavin Uptake via Induction of Expression of Riboflavin Transporter-3 (RFVT3). Dig Dis Sci. 2019 01; 64(1):84-92. PMID: 30276569.
      View in: PubMed
    12. Said HM, Nexo E. Gastrointestinal Handling of Water-Soluble Vitamins. Compr Physiol. 2018 09 14; 8(4):1291-1311. PMID: 30215865.
      View in: PubMed
    13. Anandam KY, Alwan OA, Subramanian VS, Srinivasan P, Kapadia R, Said HM. Effect of the proinflammatory cytokine TNF-a on intestinal riboflavin uptake: inhibition mediated via transcriptional mechanism(s). Am J Physiol Cell Physiol. 2018 11 01; 315(5):C653-C663. PMID: 30156861.
      View in: PubMed
    14. Sabui S, Kapadia R, Ghosal A, Schneider M, Lambrecht NWG, Said HM. Biotin and pantothenic acid oversupplementation to conditional SLC5A6 KO mice prevents the development of intestinal mucosal abnormalities and growth defects. Am J Physiol Cell Physiol. 2018 07 01; 315(1):C73-C79. PMID: 29669219.
      View in: PubMed
    15. Subramanian VS, Sabui S, Subramenium GA, Marchant JS, Said HM. Tumor necrosis factor alpha reduces intestinal vitamin C uptake: a role for NF-?B-mediated signaling. Am J Physiol Gastrointest Liver Physiol. 2018 08 01; 315(2):G241-G248. PMID: 29631379.
      View in: PubMed
    16. Elahi A, Sabui S, Narasappa NN, Agrawal S, Lambrecht NW, Agrawal A, Said HM. Biotin Deficiency Induces Th1- and Th17-Mediated Proinflammatory Responses in Human CD4+ T Lymphocytes via Activation of the mTOR Signaling Pathway. J Immunol. 2018 04 15; 200(8):2563-2570. PMID: 29531163.
      View in: PubMed
    17. Nabokina SM, Ramos MB, Said HM. Correction: Mechanism(S) Involved in the Colon-Specific Expression of the Thiamine Pyrophosphate (Tpp) Transporter. PLoS One. 2017; 12(10):e0186550. PMID: 29020075.
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    18. Subramanian VS, Nabokina SM, Lin-Moshier Y, Marchant JS, Said HM. Correction: Mitochondrial Uptake of Thiamin Pyrophosphate: Physiological and Cell Biological Aspects. PLoS One. 2017; 12(10):e0186541. PMID: 29020070.
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    19. Subramanian VS, Sabui S, Moradi H, Marchant JS, Said HM. Inhibition of intestinal ascorbic acid uptake by lipopolysaccharide is mediated via transcriptional mechanisms. Biochim Biophys Acta Biomembr. 2018 Feb; 1860(2):556-565. PMID: 29030247.
      View in: PubMed
    20. Nabokina SM, Inoue K, Subramanian VS, Valle JE, Yuasa H, Said HM. Molecular identification and functional characterization of the human colonic thiamine pyrophosphate transporter. J Biol Chem. 2017 10 06; 292(40):16526. PMID: 28986434.
      View in: PubMed
    21. Anandam KY, Srinivasan P, Subramanian VS, Said HM. Molecular mechanisms involved in the adaptive regulation of the colonic thiamin pyrophosphate uptake process. Am J Physiol Cell Physiol. 2017 12 01; 313(6):C655-C663. PMID: 28931541.
      View in: PubMed
    22. Lakhan R, Subramanian VS, Said HM. Role of MicroRNA-423-5p in posttranscriptional regulation of the intestinal riboflavin transporter-3. Am J Physiol Gastrointest Liver Physiol. 2017 Dec 01; 313(6):G589-G598. PMID: 28912250.
      View in: PubMed
    23. Sabui S, Subramanian VS, Kapadia R, Said HM. Adaptive regulation of pancreatic acinar mitochondrial thiamin pyrophosphate uptake process: possible involvement of epigenetic mechanism(s). Am J Physiol Gastrointest Liver Physiol. 2017 Nov 01; 313(5):G448-G455. PMID: 28729247.
      View in: PubMed
    24. Subramanian VS, Sabui S, Teafatiller T, Bohl JA, Said HM. Structure/functional aspects of the human riboflavin transporter-3 (SLC52A3): role of the predicted glycosylation and substrate-interacting sites. Am J Physiol Cell Physiol. 2017 Aug 01; 313(2):C228-C238. PMID: 28637675.
      View in: PubMed
    25. Lakhan R, Said HM. Lipopolysaccharide inhibits colonic biotin uptake via interference with membrane expression of its transporter: a role for a casein kinase 2-mediated pathway. Am J Physiol Cell Physiol. 2017 Apr 01; 312(4):C376-C384. PMID: 28052864.
      View in: PubMed
    26. Subramanian VS, Srinivasan P, Wildman AJ, Marchant JS, Said HM. Molecular mechanism(s) involved in differential expression of vitamin C transporters along the intestinal tract. Am J Physiol Gastrointest Liver Physiol. 2017 Apr 01; 312(4):G340-G347. PMID: 27932501.
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    27. Subramanian VS, Constantinescu AR, Benke PJ, Said HM. Mutations in SLC5A6 associated with brain, immune, bone, and intestinal dysfunction in a young child. Hum Genet. 2017 02; 136(2):253-261. PMID: 27904971.
      View in: PubMed
    28. Udhayabanu T, Subramanian VS, Teafatiller T, Gowda VK, Raghavan VS, Varalakshmi P, Said HM, Ashokkumar B. SLC52A2 [p.P141T] and SLC52A3 [p.N21S] causing Brown-Vialetto-Van Laere Syndrome in an Indian patient: First genetically proven case with mutations in two riboflavin transporters. Clin Chim Acta. 2016 Nov 01; 462:210-214. PMID: 27702554.
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    29. Sassoon CS, Zhu E, Fang L, Subramanian VS, Said HM. Inhibition of Intestinal Thiamin Transport in Rat Model of Sepsis. Crit Care Med. 2016 09; 44(9):e875-81. PMID: 27065466.
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    30. Sabui S, Bohl JA, Kapadia R, Cogburn K, Ghosal A, Lambrecht NW, Said HM. Role of the sodium-dependent multivitamin transporter (SMVT) in the maintenance of intestinal mucosal integrity. Am J Physiol Gastrointest Liver Physiol. 2016 09 01; 311(3):G561-70. PMID: 27492331.
      View in: PubMed
    31. Moradi H, Said HM. Functional thiamine deficiency in end-stage renal disease: malnutrition despite ample nutrients. Kidney Int. 2016 08; 90(2):252-254. PMID: 27418090.
      View in: PubMed
    32. Agrawal S, Agrawal A, Said HM. Biotin deficiency enhances the inflammatory response of human dendritic cells. Am J Physiol Cell Physiol. 2016 09 01; 311(3):C386-91. PMID: 27413170.
      View in: PubMed
    33. Sabui S, Subramanian VS, Kapadia R, Said HM. Structure-function characterization of the human mitochondrial thiamin pyrophosphate transporter (hMTPPT; SLC25A19): Important roles for Ile(33), Ser(34), Asp(37), His(137) and Lys(291). Biochim Biophys Acta. 2016 08; 1858(8):1883-90. PMID: 27188525.
      View in: PubMed
    34. Subramanian VS, Srinivasan P, Said HM. Uptake of ascorbic acid by pancreatic acinar cells is negatively impacted by chronic alcohol exposure. Am J Physiol Cell Physiol. 2016 07 01; 311(1):C129-35. PMID: 27122159.
      View in: PubMed
    35. Srinivasan P, Thrower EC, Gorelick FS, Said HM. Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Am J Physiol Gastrointest Liver Physiol. 2016 05 15; 310(10):G874-83. PMID: 26999808.
      View in: PubMed
    36. Nabokina SM, Ramos MB, Said HM. Mechanism(S) Involved in the Colon-Specific Expression of the Thiamine Pyrophosphate (Tpp) Transporter. PLoS One. 2016; 11(2):e0149255. PMID: 26901654.
      View in: PubMed
    37. Nabokina SM, Subramanian VS, Said HM. The human colonic thiamine pyrophosphate transporter (hTPPT) is a glycoprotein and N-linked glycosylation is important for its function. Biochim Biophys Acta. 2016 Apr; 1858(4):866-71. PMID: 26828122.
      View in: PubMed
    38. Subramanian VS, Lambrecht N, Lytle C, Said HM. Conditional (intestinal-specific) knockout of the riboflavin transporter-3 (RFVT-3) impairs riboflavin absorption. Am J Physiol Gastrointest Liver Physiol. 2016 Feb 15; 310(4):G285-93. PMID: 26660539.
      View in: PubMed
    39. Srinivasan P, Thrower EC, Loganathan G, Balamurugan AN, Subramanian VS, Gorelick FS, Said HM. Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells. PLoS One. 2015; 10(12):e0143575. PMID: 26633299.
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    40. Manimaran P, Subramanian VS, Karthi S, Gandhimathi K, Varalakshmi P, Ganesh R, Rathinavel A, Said HM, Ashokkumar B. Novel nonsense mutation (p.Ile411Metfs*12) in the SLC19A2 gene causing Thiamine Responsive Megaloblastic Anemia in an Indian patient. Clin Chim Acta. 2016 Jan 15; 452:44-9. PMID: 26549656.
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    41. Srinivasan P, Nabokina S, Said HM. Chronic alcohol exposure affects pancreatic acinar mitochondrial thiamin pyrophosphate uptake: studies with mouse 266-6 cell line and primary cells. Am J Physiol Gastrointest Liver Physiol. 2015 Nov 01; 309(9):G750-8. PMID: 26316591.
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    42. Kaji I, Akiba Y, Said H, Narimatsu K, Kaunitz JD. Luminal 5-HT stimulates colonic bicarbonate secretion in rats. Br J Pharmacol. 2015 Oct; 172(19):4655-70. PMID: 26061462.
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    43. Subramanian VS, Ghosal A, Kapadia R, Nabokina SM, Said HM. Molecular Mechanisms Mediating the Adaptive Regulation of Intestinal Riboflavin Uptake Process. PLoS One. 2015; 10(6):e0131698. PMID: 26121134.
      View in: PubMed
    44. Ghosal A, Jellbauer S, Kapadia R, Raffatellu M, Said HM. Salmonella infection inhibits intestinal biotin transport: cellular and molecular mechanisms. Am J Physiol Gastrointest Liver Physiol. 2015 Jul 15; 309(2):G123-31. PMID: 25999427.
      View in: PubMed
    45. Subramanian VS, Kapadia R, Ghosal A, Said HM. Identification of residues/sequences in the human riboflavin transporter-2 that is important for function and cell biology. Nutr Metab (Lond). 2015; 12:13. PMID: 25798182.
      View in: PubMed
    46. Nabokina SM, Ramos MB, Valle JE, Said HM. Regulation of basal promoter activity of the human thiamine pyrophosphate transporter SLC44A4 in human intestinal epithelial cells. Am J Physiol Cell Physiol. 2015 05 01; 308(9):C750-7. PMID: 25715703.
      View in: PubMed
    47. Said HM. Water-soluble vitamins. World Rev Nutr Diet. 2015; 111:30-7. PMID: 25418386.
      View in: PubMed
    48. Ghosal A, Sabui S, Said HM. Identification and characterization of the minimal 5'-regulatory region of the human riboflavin transporter-3 (SLC52A3) in intestinal epithelial cells. Am J Physiol Cell Physiol. 2015 Jan 15; 308(2):C189-96. PMID: 25394472.
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    49. Sabui S, Ghosal A, Said HM. Identification and characterization of 5'-flanking region of the human riboflavin transporter 1 gene (SLC52A1). Gene. 2014 Dec 10; 553(1):49-56. PMID: 25284511.
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    50. Srinivasan P, Kapadia R, Biswas A, Said HM. Chronic alcohol exposure inhibits biotin uptake by pancreatic acinar cells: possible involvement of epigenetic mechanisms. Am J Physiol Gastrointest Liver Physiol. 2014 Nov 01; 307(9):G941-9. PMID: 25214397.
      View in: PubMed
    51. Ghosal A, Sekar TV, Said HM. Biotin uptake by mouse and human pancreatic beta cells/islets: a regulated, lipopolysaccharide-sensitive carrier-mediated process. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 01; 307(3):G365-73. PMID: 24904078.
      View in: PubMed
    52. Srinivasan P, Subramanian VS, Said HM. Mechanisms involved in the inhibitory effect of chronic alcohol exposure on pancreatic acinar thiamin uptake. Am J Physiol Gastrointest Liver Physiol. 2014 Apr 01; 306(7):G631-9. PMID: 24525018.
      View in: PubMed
    53. Nabokina SM, Inoue K, Subramanian VS, Valle JE, Yuasa H, Said HM. Molecular identification and functional characterization of the human colonic thiamine pyrophosphate transporter. J Biol Chem. 2014 Feb 14; 289(7):4405-16. PMID: 24379411.
      View in: PubMed
    54. Subramanian VS, Nabokina SM, Said HM. Association of TM4SF4 with the human thiamine transporter-2 in intestinal epithelial cells. Dig Dis Sci. 2014 Mar; 59(3):583-90. PMID: 24282057.
      View in: PubMed
    55. Srinivasan P, Subramanian VS, Said HM. Effect of the cigarette smoke component, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), on physiological and molecular parameters of thiamin uptake by pancreatic acinar cells. PLoS One. 2013; 8(11):e78853. PMID: 24244374.
      View in: PubMed
    56. Ghosal A, Chatterjee NS, Chou T, Said HM. Enterotoxigenic Escherichia coli infection and intestinal thiamin uptake: studies with intestinal epithelial Caco-2 monolayers. Am J Physiol Cell Physiol. 2013 Dec 01; 305(11):C1185-91. PMID: 24133060.
      View in: PubMed
    57. Subramanian VS, Nabokina SM, Lin-Moshier Y, Marchant JS, Said HM. Mitochondrial uptake of thiamin pyrophosphate: physiological and cell biological aspects. PLoS One. 2013; 8(8):e73503. PMID: 24023687.
      View in: PubMed
    58. Said HM. Recent advances in transport of water-soluble vitamins in organs of the digestive system: a focus on the colon and the pancreas. Am J Physiol Gastrointest Liver Physiol. 2013 Nov; 305(9):G601-10. PMID: 23989008.
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    59. Nabokina SM, Subramanian VS, Valle JE, Said HM. Adaptive regulation of human intestinal thiamine uptake by extracellular substrate level: a role for THTR-2 transcriptional regulation. Am J Physiol Gastrointest Liver Physiol. 2013 Oct 15; 305(8):G593-9. PMID: 23989004.
      View in: PubMed
    60. Nabokina SM, Valle JE, Said HM. Characterization of the human mitochondrial thiamine pyrophosphate transporter SLC25A19 minimal promoter: a role for NF-Y in regulating basal transcription. Gene. 2013 Oct 10; 528(2):248-55. PMID: 23872534.
      View in: PubMed
    61. Subramanian VS, Subramanya SB, Ghosal A, Said HM. Chronic alcohol feeding inhibits physiological and molecular parameters of intestinal and renal riboflavin transport. Am J Physiol Cell Physiol. 2013 Sep; 305(5):C539-46. PMID: 23804199.
      View in: PubMed
    62. Kumar JS, Subramanian VS, Kapadia R, Kashyap ML, Said HM. Mammalian colonocytes possess a carrier-mediated mechanism for uptake of vitamin B3 (niacin): studies utilizing human and mouse colonic preparations. Am J Physiol Gastrointest Liver Physiol. 2013 Aug 01; 305(3):G207-13. PMID: 23744738.
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    63. Augagneur Y, Jaubert L, Schiavoni M, Pachikara N, Garg A, Usmani-Brown S, Wesolowski D, Zeller S, Ghosal A, Cornillot E, Said HM, Kumar P, Altman S, Ben Mamoun C. Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum. J Biol Chem. 2013 Jul 12; 288(28):20558-67. PMID: 23729665.
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    64. Al-Sadi R, Guo S, Ye D, Dokladny K, Alhmoud T, Ereifej L, Said HM, Ma TY. Mechanism of IL-1ß modulation of intestinal epithelial barrier involves p38 kinase and activating transcription factor-2 activation. J Immunol. 2013 Jun 15; 190(12):6596-606. PMID: 23656735.
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    65. Moradi H, Vaziri ND, Kashyap ML, Said HM, Kalantar-Zadeh K. Role of HDL dysfunction in end-stage renal disease: a double-edged sword. J Ren Nutr. 2013 May; 23(3):203-6. PMID: 23611547.
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    66. Subramanian VS, Nabokina SM, Patton JR, Marchant JS, Moradi H, Said HM. Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis. Am J Physiol Gastrointest Liver Physiol. 2013 Jun 15; 304(12):G1079-86. PMID: 23599041.
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    67. Biswas A, Elmatari D, Rothman J, LaMunyon CW, Said HM. Identification and functional characterization of the Caenorhabditis elegans riboflavin transporters rft-1 and rft-2. PLoS One. 2013; 8(3):e58190. PMID: 23483992.
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    68. Subramanian VS, Ghosal A, Subramanya SB, Lytle C, Said HM. Differentiation-dependent regulation of intestinal vitamin B(2) uptake: studies utilizing human-derived intestinal epithelial Caco-2 cells and native rat intestine. Am J Physiol Gastrointest Liver Physiol. 2013 Apr 15; 304(8):G741-8. PMID: 23413253.
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    69. Moradi H, Said HM, Vaziri ND. Post-transcriptional nature of uremia-induced downregulation of hepatic apolipoprotein A-I production. Transl Res. 2013 Jun; 161(6):477-85. PMID: 23219399.
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    70. Guo S, Al-Sadi R, Said HM, Ma TY. Lipopolysaccharide causes an increase in intestinal tight junction permeability in vitro and in vivo by inducing enterocyte membrane expression and localization of TLR-4 and CD14. Am J Pathol. 2013 Feb; 182(2):375-87. PMID: 23201091.
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    71. Ghosal A, Lambrecht N, Subramanya SB, Kapadia R, Said HM. Conditional knockout of the Slc5a6 gene in mouse intestine impairs biotin absorption. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 01; 304(1):G64-71. PMID: 23104561.
      View in: PubMed
    72. Subramanian VS, Subramanya SB, Ghosal A, Marchant JS, Harada A, Said HM. Modulation of function of sodium-dependent vitamin C transporter 1 (SVCT1) by Rab8a in intestinal epithelial cells: studies utilizing Caco-2 cells and Rab8a knockout mice. Dig Dis Sci. 2013 Mar; 58(3):641-9. PMID: 23014846.
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    73. Ghosal A, Said HM. Mechanism and regulation of vitamin B2 (riboflavin) uptake by mouse and human pancreatic ß-cells/islets: physiological and molecular aspects. Am J Physiol Gastrointest Liver Physiol. 2012 Nov 01; 303(9):G1052-8. PMID: 22917629.
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    74. Nabokina SM, Said HM. A high-affinity and specific carrier-mediated mechanism for uptake of thiamine pyrophosphate by human colonic epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2012 Aug 01; 303(3):G389-95. PMID: 22628036.
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    75. Nabokina SM, Subramanian VS, Said HM. Effect of clinical mutations on functionality of the human riboflavin transporter-2 (hRFT-2). Mol Genet Metab. 2012 Apr; 105(4):652-7. PMID: 22273710.
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    76. Said HM. Biotin: biochemical, physiological and clinical aspects. Subcell Biochem. 2012; 56:1-19. PMID: 22116691.
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    77. Said HM, Kock MM, Ismail NA, Baba K, Omar SV, Osman AG, Hoosen AA, Ehlers MM. Evaluation of the GenoType® MTBDRsl assay for susceptibility testing of second-line anti-tuberculosis drugs. Int J Tuberc Lung Dis. 2012 Jan; 16(1):104-9. PMID: 22236854.
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    78. Subramanian VS, Subramanya SB, Said HM. Relative contribution of THTR-1 and THTR-2 in thiamin uptake by pancreatic acinar cells: studies utilizing Slc19a2 and Slc19a3 knockout mouse models. Am J Physiol Gastrointest Liver Physiol. 2012 Mar 01; 302(5):G572-8. PMID: 22194418.
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    79. Mansour A, Nabil M, Ali-Labib R, Said H, Annos F. Reciprocal expression of survivin and SMAC/DIABLO in primary breast cancer. Med Oncol. 2012 Dec; 29(4):2535-42. PMID: 22161156.
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    80. Ghosal A, Said HM. Cys(294) is essential for the function of the human sodium-dependent multivitamin transporter. Biochim Biophys Acta. 2012 Jan; 1818(1):97-102. PMID: 22015582.
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    81. Biswas A, Senthilkumar SR, Said HM. Effect of chronic alcohol exposure on folate uptake by liver mitochondria. Am J Physiol Cell Physiol. 2012 Jan 01; 302(1):C203-9. PMID: 21956163.
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    82. Subramanya SB, Subramanian VS, Sekar VT, Said HM. Thiamin uptake by pancreatic acinar cells: effect of chronic alcohol feeding/exposure. Am J Physiol Gastrointest Liver Physiol. 2011 Nov; 301(5):G896-904. PMID: 21868632.
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    83. Subramanian VS, Subramanya SB, Rapp L, Marchant JS, Ma TY, Said HM. Differential expression of human riboflavin transporters -1, -2, and -3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake. Biochim Biophys Acta. 2011 Dec; 1808(12):3016-21. PMID: 21854757.
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    84. Nabokina SM, Senthilkumar SR, Said HM. Tspan-1 interacts with the thiamine transporter-1 in human intestinal epithelial cells and modulates its stability. Am J Physiol Gastrointest Liver Physiol. 2011 Nov; 301(5):G808-13. PMID: 21836059.
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    85. Said HM. Intestinal absorption of water-soluble vitamins in health and disease. Biochem J. 2011 Aug 01; 437(3):357-72. PMID: 21749321.
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    86. Ghosal A, Subramanian VS, Said HM. Role of the putative N-glycosylation and PKC-phosphorylation sites of the human sodium-dependent multivitamin transporter (hSMVT) in function and regulation. Biochim Biophys Acta. 2011 Aug; 1808(8):2073-80. PMID: 21570947.
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    87. Subramanian VS, Rapp L, Marchant JS, Said HM. Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2011 Jul; 301(1):G100-9. PMID: 21512156.
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    88. Al-Sadi R, Ye D, Said HM, Ma TY. Cellular and molecular mechanism of interleukin-1ß modulation of Caco-2 intestinal epithelial tight junction barrier. J Cell Mol Med. 2011 Apr; 15(4):970-82. PMID: 20406328.
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    89. Subramanian VS, Subramanya SB, Said HM. Chronic alcohol exposure negatively impacts the physiological and molecular parameters of the renal biotin reabsorption process. Am J Physiol Renal Physiol. 2011 Mar; 300(3):F611-7. PMID: 21209005.
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    90. Nabokina SM, Subramanian VS, Said HM. Association of PDZ-containing protein PDZD11 with the human sodium-dependent multivitamin transporter. Am J Physiol Gastrointest Liver Physiol. 2011 Apr; 300(4):G561-7. PMID: 21183659.
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    91. Bukhari FJ, Moradi H, Gollapudi P, Ju Kim H, Vaziri ND, Said HM. Effect of chronic kidney disease on the expression of thiamin and folic acid transporters. Nephrol Dial Transplant. 2011 Jul; 26(7):2137-44. PMID: 21149507.
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    92. Subramanya SB, Subramanian VS, Kumar JS, Hoiness R, Said HM. Inhibition of intestinal biotin absorption by chronic alcohol feeding: cellular and molecular mechanisms. Am J Physiol Gastrointest Liver Physiol. 2011 Mar; 300(3):G494-501. PMID: 21148397.
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    93. Al-Sadi R, Ye D, Said HM, Ma TY. IL-1beta-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-kappaB pathway. Am J Pathol. 2010 Nov; 177(5):2310-22. PMID: 21048223.
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    94. Ghosal A, Said HM. Structure-function activity of the human sodium-dependent multivitamin transporter: role of His¹¹⁵ and His²54. Am J Physiol Cell Physiol. 2011 Jan; 300(1):C97-104. PMID: 20962270.
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    95. Subramanya SB, Subramanian VS, Said HM. Chronic alcohol consumption and intestinal thiamin absorption: effects on physiological and molecular parameters of the uptake process. Am J Physiol Gastrointest Liver Physiol. 2010 Jul; 299(1):G23-31. PMID: 20448146.
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    96. Austin MU, Liau WS, Balamurugan K, Ashokkumar B, Said HM, LaMunyon CW. Knockout of the folate transporter folt-1 causes germline and somatic defects in C. elegans. BMC Dev Biol. 2010 May 04; 10:46. PMID: 20441590.
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    97. Subramanian VS, Subramanya SB, Tsukamoto H, Said HM. Effect of chronic alcohol feeding on physiological and molecular parameters of renal thiamin transport. Am J Physiol Renal Physiol. 2010 Jul; 299(1):F28-34. PMID: 20427470.
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    98. Said HM, Mee L, Sekar VT, Ashokkumar B, Pandol SJ. Mechanism and regulation of folate uptake by pancreatic acinar cells: effect of chronic alcohol consumption. Am J Physiol Gastrointest Liver Physiol. 2010 Jun; 298(6):G985-93. PMID: 20360131.
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    99. Subramanian VS, Marchant JS, Said HM. Molecular determinants dictating cell surface expression of the human sodium-dependent vitamin C transporter-2 in human liver cells. Am J Physiol Gastrointest Liver Physiol. 2010 Feb; 298(2):G267-74. PMID: 19926816.
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    100. Reidling JC, Lambrecht N, Kassir M, Said HM. Impaired intestinal vitamin B1 (thiamin) uptake in thiamin transporter-2-deficient mice. Gastroenterology. 2010 May; 138(5):1802-9. PMID: 19879271.
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    101. Ashokkumar B, Kumar JS, Hecht GA, Said HM. Enteropathogenic Escherichia coli inhibits intestinal vitamin B1 (thiamin) uptake: studies with human-derived intestinal epithelial Caco-2 cells. Am J Physiol Gastrointest Liver Physiol. 2009 Oct; 297(4):G825-33. PMID: 19628653.
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    102. Ashokkumar B, Nabokina SM, Ma TY, Said HM. Identification of dynein light chain road block-1 as a novel interaction partner with the human reduced folate carrier. Am J Physiol Gastrointest Liver Physiol. 2009 Sep; 297(3):G480-7. PMID: 19571232.
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    103. Mee L, Nabokina SM, Sekar VT, Subramanian VS, Maedler K, Said HM. Pancreatic beta cells and islets take up thiamin by a regulated carrier-mediated process: studies using mice and human pancreatic preparations. Am J Physiol Gastrointest Liver Physiol. 2009 Jul; 297(1):G197-206. PMID: 19423748.
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    104. Subramanian VS, Marchant JS, Boulware MJ, Ma TY, Said HM. Membrane targeting and intracellular trafficking of the human sodium-dependent multivitamin transporter in polarized epithelial cells. Am J Physiol Cell Physiol. 2009 Apr; 296(4):C663-71. PMID: 19211916.
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    105. Said HM. Cell and molecular aspects of human intestinal biotin absorption. J Nutr. 2009 Jan; 139(1):158-62. PMID: 19056639.
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    106. Mock DM, Said H. Introduction to "Advances in understanding of the biological role of biotin at the clinical, biochemical, and molecular level". J Nutr. 2009 Jan; 139(1):152-3. PMID: 19056638.
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    107. Reidling JC, Subramanian VS, Dahhan T, Sadat M, Said HM. Mechanisms and regulation of vitamin C uptake: studies of the hSVCT systems in human liver epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2008 Dec; 295(6):G1217-27. PMID: 18845575.
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    108. Subramanian VS, Reidling JC, Said HM. Differentiation-dependent regulation of the intestinal folate uptake process: studies with Caco-2 cells and native mouse intestine. Am J Physiol Cell Physiol. 2008 Sep; 295(3):C828-35. PMID: 18650265.
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    109. Subramanian VS, Marchant JS, Reidling JC, Said HM. N-Glycosylation is required for Na+-dependent vitamin C transporter functionality. Biochem Biophys Res Commun. 2008 Sep 12; 374(1):123-7. PMID: 18619416.
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    110. Said ZM, Subramanian VS, Vaziri ND, Said HM. Pyridoxine uptake by colonocytes: a specific and regulated carrier-mediated process. Am J Physiol Cell Physiol. 2008 May; 294(5):C1192-7. PMID: 18353902.
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    111. Subramanian VS, Marchant JS, Said HM. Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia. Am J Physiol Cell Physiol. 2008 Jan; 294(1):C233-40. PMID: 18003745.
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    112. Said HM, Nabokina SM, Balamurugan K, Mohammed ZM, Urbina C, Kashyap ML. Mechanism of nicotinic acid transport in human liver cells: experiments with HepG2 cells and primary hepatocytes. Am J Physiol Cell Physiol. 2007 Dec; 293(6):C1773-8. PMID: 17928533.
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    113. Subramanian VS, Marchant JS, Ye D, Ma TY, Said HM. Tight junction targeting and intracellular trafficking of occludin in polarized epithelial cells. Am J Physiol Cell Physiol. 2007 Nov; 293(5):C1717-26. PMID: 17855770.
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    114. Subramanian VS, Marchant JS, Said HM. Targeting and intracellular trafficking of clinically relevant hTHTR1 mutations in human cell lines. Clin Sci (Lond). 2007 Jul; 113(2):93-102. PMID: 17331069.
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    115. Ashokkumar B, Mohammed ZM, Vaziri ND, Said HM. Effect of folate oversupplementation on folate uptake by human intestinal and renal epithelial cells. Am J Clin Nutr. 2007 Jul; 86(1):159-66. PMID: 17616776.
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    116. Balamurugan K, Ashokkumar B, Moussaif M, Sze JY, Said HM. Cloning and functional characterization of a folate transporter from the nematode Caenorhabditis elegans. Am J Physiol Cell Physiol. 2007 Aug; 293(2):C670-81. PMID: 17475669.
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    117. Subramanian VS, Mohammed ZM, Molina A, Marchant JS, Vaziri ND, Said HM. Vitamin B1 (thiamine) uptake by human retinal pigment epithelial (ARPE-19) cells: mechanism and regulation. J Physiol. 2007 Jul 01; 582(Pt 1):73-85. PMID: 17463047.
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    118. Reidling JC, Said HM. Regulation of the human biotin transporter hSMVT promoter by KLF-4 and AP-2: confirmation of promoter activity in vivo. Am J Physiol Cell Physiol. 2007 Apr; 292(4):C1305-12. PMID: 17135299.
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    119. Reidling JC, Nabokina SM, Said HM. Molecular mechanisms involved in the adaptive regulation of human intestinal biotin uptake: A study of the hSMVT system. Am J Physiol Gastrointest Liver Physiol. 2007 Jan; 292(1):G275-81. PMID: 16959947.
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    120. Subramanian VS, Marchant JS, Said HM. Biotin-responsive basal ganglia disease-linked mutations inhibit thiamine transport via hTHTR2: biotin is not a substrate for hTHTR2. Am J Physiol Cell Physiol. 2006 Nov; 291(5):C851-9. PMID: 16790503.
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    121. Ashokkumar B, Vaziri ND, Said HM. Thiamin uptake by the human-derived renal epithelial (HEK-293) cells: cellular and molecular mechanisms. Am J Physiol Renal Physiol. 2006 Oct; 291(4):F796-805. PMID: 16705148.
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    122. Said HM, Mohammed ZM. Intestinal absorption of water-soluble vitamins: an update. Curr Opin Gastroenterol. 2006 Mar; 22(2):140-6. PMID: 16462170.
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    123. Balamurugan K, Said HM. Role of reduced folate carrier in intestinal folate uptake. Am J Physiol Cell Physiol. 2006 Jul; 291(1):C189-93. PMID: 16495369.
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    124. Schrader S, Kneuer C, Said HM, Honscha W. Alternative transcripts of rat slc19a1: defective sorting and inefficient expression of alternative splicing products--an addendum. DNA Seq. 2006 Feb; 17(1):83-6. PMID: 16753822.
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    125. Reidling JC, Nabokina SM, Balamurugan K, Said HM. Developmental maturation of intestinal and renal thiamin uptake: studies in wild-type and transgenic mice carrying human THTR-1 and 2 promoters. J Cell Physiol. 2006 Feb; 206(2):371-7. PMID: 16206251.
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    126. Subramanian VS, Marchant JS, Said HM. Targeting and trafficking of the human thiamine transporter-2 in epithelial cells. J Biol Chem. 2006 Feb 24; 281(8):5233-45. PMID: 16371350.
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    127. Nabokina SM, Reidling JC, Said HM. Differentiation-dependent up-regulation of intestinal thiamin uptake: cellular and molecular mechanisms. J Biol Chem. 2005 Sep 23; 280(38):32676-82. PMID: 16055442.
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    128. Said HM, Wang S, Ma TY. Mechanism of riboflavin uptake by cultured human retinal pigment epithelial ARPE-19 cells: possible regulation by an intracellular Ca2+-calmodulin-mediated pathway. J Physiol. 2005 Jul 15; 566(Pt 2):369-77. PMID: 15878949.
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    129. Ma TY, Boivin MA, Ye D, Pedram A, Said HM. Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression. Am J Physiol Gastrointest Liver Physiol. 2005 Mar; 288(3):G422-30. PMID: 15701621.
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    130. Nabokina SM, Kashyap ML, Said HM. Mechanism and regulation of human intestinal niacin uptake. Am J Physiol Cell Physiol. 2005 Jul; 289(1):C97-103. PMID: 15728713.
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    131. Reidling JC, Said HM. Adaptive regulation of intestinal thiamin uptake: molecular mechanism using wild-type and transgenic mice carrying hTHTR-1 and -2 promoters. Am J Physiol Gastrointest Liver Physiol. 2005 Jun; 288(6):G1127-34. PMID: 15705657.
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    132. Balamurugan K, Vaziri ND, Said HM. Biotin uptake by human proximal tubular epithelial cells: cellular and molecular aspects. Am J Physiol Renal Physiol. 2005 Apr; 288(4):F823-31. PMID: 15561972.
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    133. Nabokina SM, Said HM. Characterization of the 5'-regulatory region of the human thiamin transporter SLC19A3: in vitro and in vivo studies. Am J Physiol Gastrointest Liver Physiol. 2004 Oct; 287(4):G822-9. PMID: 15217784.
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    134. Subramanian VS, Marchant JS, Boulware MJ, Said HM. A C-terminal region dictates the apical plasma membrane targeting of the human sodium-dependent vitamin C transporter-1 in polarized epithelia. J Biol Chem. 2004 Jun 25; 279(26):27719-28. PMID: 15084584.
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    135. Nabokina SM, Ma TY, Said HM. Mechanism and regulation of folate uptake by human pancreatic epithelial MIA PaCa-2 cells. Am J Physiol Cell Physiol. 2004 Jul; 287(1):C142-8. PMID: 14998787.
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    136. Ma TY, Iwamoto GK, Hoa NT, Akotia V, Pedram A, Boivin MA, Said HM. TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation. Am J Physiol Gastrointest Liver Physiol. 2004 Mar; 286(3):G367-76. PMID: 14766535.
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    137. Crisp SE, Griffin JB, White BR, Toombs CF, Camporeale G, Said HM, Zempleni J. Biotin supply affects rates of cell proliferation, biotinylation of carboxylases and histones, and expression of the gene encoding the sodium-dependent multivitamin transporter in JAr choriocarcinoma cells. Eur J Nutr. 2004 Feb; 43(1):23-31. PMID: 14991266.
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    138. Said HM. Recent advances in carrier-mediated intestinal absorption of water-soluble vitamins. Annu Rev Physiol. 2004; 66:419-46. PMID: 14977409.
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    139. Boulware MJ, Subramanian VS, Said HM, Marchant JS. Polarized expression of members of the solute carrier SLC19A gene family of water-soluble multivitamin transporters: implications for physiological function. Biochem J. 2003 Nov 15; 376(Pt 1):43-8. PMID: 14602044.
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    140. Said HM, Balamurugan K, Subramanian VS, Marchant JS. Expression and functional contribution of hTHTR-2 in thiamin absorption in human intestine. Am J Physiol Gastrointest Liver Physiol. 2004 Mar; 286(3):G491-8. PMID: 14615284.
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    141. Reidling JC, Said HM. In vitro and in vivo characterization of the minimal promoter region of the human thiamin transporter SLC19A2. Am J Physiol Cell Physiol. 2003 Sep; 285(3):C633-41. PMID: 12900388.
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    142. Subramanian VS, Chatterjee N, Said HM. Folate uptake in the human intestine: promoter activity and effect of folate deficiency. J Cell Physiol. 2003 Aug; 196(2):403-8. PMID: 12811835.
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    143. Said HM, Ortiz A, Ma TY. A carrier-mediated mechanism for pyridoxine uptake by human intestinal epithelial Caco-2 cells: regulation by a PKA-mediated pathway. Am J Physiol Cell Physiol. 2003 Nov; 285(5):C1219-25. PMID: 12867360.
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    144. Balamurugan K, Said HM. Ontogenic regulation of folate transport across rat jejunal brush-border membrane. Am J Physiol Gastrointest Liver Physiol. 2003 Nov; 285(5):G1068-73. PMID: 12842826.
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    145. Nabokina SM, Subramanian VS, Said HM. Comparative analysis of ontogenic changes in renal and intestinal biotin transport in the rat. Am J Physiol Renal Physiol. 2003 Apr; 284(4):F737-42. PMID: 12620923.
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    146. Balamurugan K, Ortiz A, Said HM. Biotin uptake by human intestinal and liver epithelial cells: role of the SMVT system. Am J Physiol Gastrointest Liver Physiol. 2003 Jul; 285(1):G73-7. PMID: 12646417.
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    147. Dudeja PK, Tyagi S, Gill R, Said HM. Evidence for a carrier-mediated mechanism for thiamine transport to human jejunal basolateral membrane vesicles. Dig Dis Sci. 2003 Jan; 48(1):109-15. PMID: 12645798.
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    148. Said HM, Reidling JC, Ortiz A. Cellular and molecular aspects of thiamin uptake by human liver cells: studies with cultured HepG2 cells. Biochim Biophys Acta. 2002 Dec 23; 1567(1-2):106-12. PMID: 12488043.
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    149. Subramanian VS, Marchant JS, Parker I, Said HM. Cell biology of the human thiamine transporter-1 (hTHTR1). Intracellular trafficking and membrane targeting mechanisms. J Biol Chem. 2003 Feb 07; 278(6):3976-84. PMID: 12454006.
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    150. Balamurugan K, Said HM. Functional role of specific amino acid residues in human thiamine transporter SLC19A2: mutational analysis. Am J Physiol Gastrointest Liver Physiol. 2002 Jul; 283(1):G37-43. PMID: 12065289.
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    151. Marchant JS, Subramanian VS, Parker I, Said HM. Intracellular trafficking and membrane targeting mechanisms of the human reduced folate carrier in Mammalian epithelial cells. J Biol Chem. 2002 Sep 06; 277(36):33325-33. PMID: 12087110.
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    152. Reidling JC, Subramanian VS, Dudeja PK, Said HM. Expression and promoter analysis of SLC19A2 in the human intestine. Biochim Biophys Acta. 2002 Apr 12; 1561(2):180-7. PMID: 11997118.
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    153. Dey S, Subramanian VS, Chatterjee NS, Rubin SA, Said HM. Characterization of the 5' regulatory region of the human sodium-dependent multivitamin transporter, hSMVT. Biochim Biophys Acta. 2002 Mar 19; 1574(2):187-92. PMID: 11955628.
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    154. Said HM, Ortiz A, Vaziri ND. Mechanism and regulation of vitamin B(6) uptake by renal tubular epithelia: studies with cultured OK cells. Am J Physiol Renal Physiol. 2002 Mar; 282(3):F465-71. PMID: 11832427.
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    155. Said HM. Biotin: the forgotten vitamin. Am J Clin Nutr. 2002 Feb; 75(2):179-80. PMID: 11815306.
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    156. Vanselow J, Fürbass R, Zsolnai A, Kalbe C, Said HM, Schwerin M. Expression of the aromatase cytochrome P450 encoding gene in cattle and sheep. J Steroid Biochem Mol Biol. 2001 Dec; 79(1-5):279-88. PMID: 11850234.
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    157. Subramanian VS, Marchant JS, Parker I, Said HM. Intracellular trafficking/membrane targeting of human reduced folate carrier expressed in Xenopus oocytes. Am J Physiol Gastrointest Liver Physiol. 2001 Dec; 281(6):G1477-86. PMID: 11705753.
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    158. Dudeja PK, Tyagi S, Kavilaveettil RJ, Gill R, Said HM. Mechanism of thiamine uptake by human jejunal brush-border membrane vesicles. Am J Physiol Cell Physiol. 2001 Sep; 281(3):C786-92. PMID: 11502555.
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    159. Said HM, Ortiz A, Subramanian VS, Neufeld EJ, Moyer MP, Dudeja PK. Mechanism of thiamine uptake by human colonocytes: studies with cultured colonic epithelial cell line NCM460. Am J Physiol Gastrointest Liver Physiol. 2001 Jul; 281(1):G144-50. PMID: 11408266.
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    160. Dudeja PK, Kode A, Alnounou M, Tyagi S, Torania S, Subramanian VS, Said HM. Mechanism of folate transport across the human colonic basolateral membrane. Am J Physiol Gastrointest Liver Physiol. 2001 Jul; 281(1):G54-60. PMID: 11408255.
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    161. Fürbass R, Said HM, Schwerin M, Vanselow J. Chromatin structure of the bovine Cyp19 promoter 1.1. DNaseI hypersensitive sites and DNA hypomethylation correlate with placental expression. Eur J Biochem. 2001 Mar; 268(5):1222-7. PMID: 11231273.
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    162. Chatterjee NS, Rubin SA, Said HM. Molecular characterization of the 5' regulatory region of rat sodium-dependent multivitamin transporter gene. Am J Physiol Cell Physiol. 2001 Mar; 280(3):C548-55. PMID: 11171574.
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    163. Said HM, Chatterjee N, Haq RU, Subramanian VS, Ortiz A, Matherly LH, Sirotnak FM, Halsted C, Rubin SA. Adaptive regulation of intestinal folate uptake: effect of dietary folate deficiency. Am J Physiol Cell Physiol. 2000 Dec; 279(6):C1889-95. PMID: 11078704.
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    164. Yanagawa N, Shih RN, Jo OD, Said HM. Riboflavin transport by isolated perfused rabbit renal proximal tubules. Am J Physiol Cell Physiol. 2000 Dec; 279(6):C1782-6. PMID: 11078692.
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    165. Said HM, Ortiz A, Moyer MP, Yanagawa N. Riboflavin uptake by human-derived colonic epithelial NCM460 cells. Am J Physiol Cell Physiol. 2000 Feb; 278(2):C270-6. PMID: 10666022.
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    166. Chatterjee NS, Kumar CK, Ortiz A, Rubin SA, Said HM. Molecular mechanism of the intestinal biotin transport process. Am J Physiol. 1999 10; 277(4):C605-13. PMID: 10516089.
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    167. Said HM, Ortiz A, Kumar CK, Chatterjee N, Dudeja PK, Rubin S. Transport of thiamine in human intestine: mechanism and regulation in intestinal epithelial cell model Caco-2. Am J Physiol. 1999 10; 277(4):C645-51. PMID: 10516094.
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    168. Said HM, Kumar C. Intestinal absorption of vitamins. Curr Opin Gastroenterol. 1999 Mar; 15(2):172-6. PMID: 17023940.
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    169. Said HM. Biotin bioavailability and estimated average requirement: why bother? Am J Clin Nutr. 1999 Mar; 69(3):352-3. PMID: 10075316.
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    170. Said HM. Cellular uptake of biotin: mechanisms and regulation. J Nutr. 1999 02; 129(2S Suppl):490S-493S. PMID: 10064315.
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    171. Yanagawa N, Jo OD, Said HM. Riboflavin transport by rabbit renal basolateral membrane vesicles. Biochim Biophys Acta. 1998 Dec 09; 1415(1):56-62. PMID: 9858685.
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    172. Said HM, Ortiz A, McCloud E, Dyer D, Moyer MP, Rubin S. Biotin uptake by human colonic epithelial NCM460 cells: a carrier-mediated process shared with pantothenic acid. Am J Physiol. 1998 11; 275(5):C1365-71. PMID: 9814986.
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    173. Said HM, Ortiz A, Ma TY, McCloud E. Riboflavin uptake by the human-derived liver cells Hep G2: mechanism and regulation. J Cell Physiol. 1998 Sep; 176(3):588-94. PMID: 9699511.
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    174. Kumar CK, Nguyen TT, Gonzales FB, Said HM. Comparison of intestinal folate carrier clone expressed in IEC-6 cells and in Xenopus oocytes. Am J Physiol. 1998 01; 274(1):C289-94. PMID: 9458739.
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    175. Kumar CK, Yanagawa N, Ortiz A, Said HM. Mechanism and regulation of riboflavin uptake by human renal proximal tubule epithelial cell line HK-2. Am J Physiol. 1998 01; 274(1):F104-10. PMID: 9458829.
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    176. Yanagawa N, Jo OD, Said HM. Riboflavin transport by rabbit renal brush border membrane vesicles. Biochim Biophys Acta. 1997 Dec 04; 1330(2):172-8. PMID: 9408170.
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    177. Dudeja PK, Torania SA, Said HM. Evidence for the existence of a carrier-mediated folate uptake mechanism in human colonic luminal membranes. Am J Physiol. 1997 Jun; 272(6 Pt 1):G1408-15. PMID: 9227476.
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    178. Kumar CK, Moyer MP, Dudeja PK, Said HM. A protein-tyrosine kinase-regulated, pH-dependent, carrier-mediated uptake system for folate in human normal colonic epithelial cell line NCM460. J Biol Chem. 1997 Mar 07; 272(10):6226-31. PMID: 9045638.
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    179. Nguyen TT, Dyer DL, Dunning DD, Rubin SA, Grant KE, Said HM. Human intestinal folate transport: cloning, expression, and distribution of complementary RNA. Gastroenterology. 1997 Mar; 112(3):783-91. PMID: 9041240.
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    180. Said HM, Ma TY, Ortiz A, Tapia A, Valerio CK. Intracellular regulation of intestinal folate uptake: studies with cultured IEC-6 epithelial cells. Am J Physiol. 1997 Feb; 272(2 Pt 1):C729-36. PMID: 9124317.
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    181. Dyer DL, Said HM. Biotin uptake in cultured cell lines. Methods Enzymol. 1997; 279:393-405. PMID: 9211292.
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    182. McCloud E, Ma TY, Grant KE, Mathis RK, Said HM. Uptake of L-carnitine by a human intestinal epithelial cell line, Caco-2. Gastroenterology. 1996 Dec; 111(6):1534-40. PMID: 8942732.
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    183. Said HM, Nguyen TT, Dyer DL, Cowan KH, Rubin SA. Intestinal folate transport: identification of a cDNA involved in folate transport and the functional expression and distribution of its mRNA. Biochim Biophys Acta. 1996 Jun 11; 1281(2):164-72. PMID: 8664315.
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    184. Said HM, McCloud E, Yanagawa N. Riboflavin uptake by rat liver basolateral membrane vesicles. Biochim Biophys Acta. 1995 Jun 14; 1236(2):244-8. PMID: 7794963.
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    185. Dyer DL, Said HM. Riboflavin uptake by native Xenopus laevis oocytes. Biochim Biophys Acta. 1995 Mar 08; 1234(1):15-21. PMID: 7880856.
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    186. Said HM, Ma TY, Grant K. Regulation of riboflavin intestinal uptake by protein kinase A: studies with Caco-2 cells. Am J Physiol. 1994 Dec; 267(6 Pt 1):G955-9. PMID: 7528980.
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    187. Said HM, Ma TY, Kamanna VS. Uptake of biotin by human hepatoma cell line, Hep G2: a carrier-mediated process similar to that of normal liver. J Cell Physiol. 1994 Dec; 161(3):483-9. PMID: 7525615.
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    188. McCloud E, Mathis RK, Grant KE, Said HM. Intestinal uptake of uridine in suckling rats: mechanism and ontogeny. Proc Soc Exp Biol Med. 1994 Sep; 206(4):425-30. PMID: 8073053.
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    189. Dyer DL, Kanai Y, Hediger MA, Rubin SA, Said HM. Expression of a rabbit renal ascorbic acid transporter in Xenopus laevis oocytes. Am J Physiol. 1994 Jul; 267(1 Pt 1):C301-6. PMID: 7519399.
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    190. Rigtrup KM, McEwen LR, Said HM, Ong DE. Retinyl ester hydrolytic activity associated with human intestinal brush border membranes. Am J Clin Nutr. 1994 Jul; 60(1):111-6. PMID: 8017323.
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    191. Ma TY, Dyer DL, Said HM. Human intestinal cell line Caco-2: a useful model for studying cellular and molecular regulation of biotin uptake. Biochim Biophys Acta. 1994 Jan 03; 1189(1):81-8. PMID: 7508263.
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    192. Said HM, Ma TY. Mechanism of riboflavine uptake by Caco-2 human intestinal epithelial cells. Am J Physiol. 1994 Jan; 266(1 Pt 1):G15-21. PMID: 8304455.
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    193. Said HM, Mohammadkhani R. Uptake of riboflavin across the brush border membrane of rat intestine: regulation by dietary vitamin levels. Gastroenterology. 1993 Nov; 105(5):1294-8. PMID: 8224633.
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    194. Horne DW, Reed KA, Hoefs J, Said HM. 5-Methyltetrahydrofolate transport in basolateral membrane vesicles from human liver. Am J Clin Nutr. 1993 Jul; 58(1):80-4. PMID: 8317394.
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    195. Said HM, Morgan T, Hoefs J. Effect of chronic portal hypertension on glutamine transport across rat intestinal brush border and basolateral membranes. J Lab Clin Med. 1993 Jul; 122(1):64-8. PMID: 8320492.
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    196. Said HM, Hollander D, Mohammadkhani R. Uptake of riboflavin by intestinal basolateral membrane vesicles: a specialized carrier-mediated process. Biochim Biophys Acta. 1993 Jun 05; 1148(2):263-8. PMID: 8504119.
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    197. Said HM, Mohammadkhani R, McCloud E. Mechanism of transport of riboflavin in rabbit intestinal brush border membrane vesicles. Proc Soc Exp Biol Med. 1993 Apr; 202(4):428-34. PMID: 8456106.
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    198. Said HM, Mohammadkhani R. Folate transport in intestinal brush border membrane: involvement of essential histidine residue(s). Biochem J. 1993 Feb 15; 290 ( Pt 1):237-40. PMID: 8439292.
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    199. Said HM, Thuy LP, Sweetman L, Schatzman B. Transport of the biotin dietary derivative biocytin (N-biotinyl-L-lysine) in rat small intestine. Gastroenterology. 1993 Jan; 104(1):75-80. PMID: 8419264.
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    200. Horne DW, Holloway RS, Said HM. Uptake of 5-formyltetrahydrofolate in isolated rat liver mitochondria is carrier-mediated. J Nutr. 1992 Nov; 122(11):2204-9. PMID: 1432261.
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    201. Said HM, Vaziri ND, Oveisi F, Hussienzadha S. Effect of chronic renal failure on intestinal transport of biotin in the rat. J Lab Clin Med. 1992 Sep; 120(3):471-5. PMID: 1517693.
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    202. Said HM, McAlister-Henn L, Mohammadkhani R, Horne DW. Uptake of biotin by isolated rat liver mitochondria. Am J Physiol. 1992 Jul; 263(1 Pt 1):G81-6. PMID: 1636720.
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    203. Said HM, Mohammadkhani R. Involvement of histidine residues and sulfhydryl groups in the function of the biotin transport carrier of rabbit intestinal brush-border membrane. Biochim Biophys Acta. 1992 Jun 30; 1107(2):238-44. PMID: 1504068.
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    204. Said HM, Hoefs J, Mohammadkhani R, Horne DW. Biotin transport in human liver basolateral membrane vesicles: a carrier-mediated, Na+ gradient-dependent process. Gastroenterology. 1992 Jun; 102(6):2120-5. PMID: 1587433.
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    205. Horne DW, Reed KA, Said HM. Transport of 5-methyltetrahydrofolate in basolateral membrane vesicles of rat liver. Am J Physiol. 1992 Jan; 262(1 Pt 1):G150-8. PMID: 1733262.
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    206. Lo RS, Said HM, Unger TF, Hollander D, Miledi R. An endogenous carrier-mediated uptake system for folate in oocytes of Xenopus laevis. Proc Biol Sci. 1991 Nov 22; 246(1316):161-5. PMID: 1685241.
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    207. Said HM. Movement of biotin across the rat intestinal basolateral membrane. Studies with membrane vesicles. Biochem J. 1991 Nov 01; 279 ( Pt 3):671-4. PMID: 1953660.
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    208. Said HM, Hollander D, Khorchid S. An Na(+)-dependent and an Na(+)-independent system for glutamine transport in rat liver basolateral membrane vesicles. Gastroenterology. 1991 Oct; 101(4):1094-101. PMID: 1889703.
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    209. Said HM, Derweesh I. Carrier-mediated mechanism for biotin transport in rabbit intestine: studies with brush-border membrane vesicles. Am J Physiol. 1991 Jul; 261(1 Pt 2):R94-7. PMID: 1858960.
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    210. Said HM, Arianas P. Transport of riboflavin in human intestinal brush border membrane vesicles. Gastroenterology. 1991 Jan; 100(1):82-8. PMID: 1983852.
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    211. Said HM, Sharifian A, Bagherzadeh A, Mock D. Chronic ethanol feeding and acute ethanol exposure in vitro: effect on intestinal transport of biotin. Am J Clin Nutr. 1990 Dec; 52(6):1083-6. PMID: 2239786.
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    212. Said HM, Korchid S, Horne DW, Howard M. Transport of biotin in basolateral membrane vesicles of rat liver. Am J Physiol. 1990 Nov; 259(5 Pt 1):G865-72. PMID: 2240226.
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    213. Said HM, Sharifian A, Bagherzadeh A. Transport of biotin in the ileum of suckling rats: characteristics and ontogeny. Pediatr Res. 1990 Sep; 28(3):266-9. PMID: 2235125.
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    214. Said HM, Polenzani L, Khorchid S, Hollander D, Miledi R. Uptake of biotin by native Xenopus laevis oocytes. Am J Physiol. 1990 Sep; 259(3 Pt 1):C397-401. PMID: 2399962.
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    215. al-Mahroos FT, Bulus N, Abumrad N, Said H, Ghishan FK. Maturational changes in glutamine transport by rat jejunal brush border membrane vesicles. Pediatr Res. 1990 May; 27(5):519-24. PMID: 2345680.
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    216. Ghishan FK, Arab N, Bulus N, Said H, Pietsch J, Abumrad N. Glutamine transport by human intestinal basolateral membrane vesicle. Am J Clin Nutr. 1990 Apr; 51(4):612-6. PMID: 2321568.
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    217. Van Voorhis K, Said HM, Abumrad N, Ghishan FK. Effect of chemically induced diabetes mellitus on glutamine transport in rat intestine. Gastroenterology. 1990 Apr; 98(4):862-6. PMID: 2155843.
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    218. Said HM, Horne DW, Mock DM. Effect of aging on intestinal biotin transport in the rat. Exp Gerontol. 1990; 25(1):67-73. PMID: 2318284.
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    219. Said HM, Chenoweth M, Dunn A. Metabolism of 3H- and 14C-labeled glutamate, proline, and alanine in normal and adrenalectomized rats using different sites of tracer administration and sampling. Metabolism. 1989 Aug; 38(8):718-27. PMID: 2569659.
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    220. Horne DW, Patterson D, Said HM. Aging: effect on hepatic metabolism and transport of folate in the rat. Am J Clin Nutr. 1989 Aug; 50(2):359-63. PMID: 2756923.
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    221. Said HM, Ong DE, Shingleton JL. Intestinal uptake of retinol: enhancement by bovine milk beta-lactoglobulin. Am J Clin Nutr. 1989 Apr; 49(4):690-4. PMID: 2929489.
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    222. Ghishan FK, Sutter W, Said H, Leonard D, Pietsch J, Abumrad N. Glutamine transport by rat basolateral membrane vesicles. Biochim Biophys Acta. 1989 Feb 13; 979(1):77-81. PMID: 2917169.
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    223. Said HM, Mock DM, Collins JC. Regulation of intestinal biotin transport in the rat: effect of biotin deficiency and supplementation. Am J Physiol. 1989 Feb; 256(2 Pt 1):G306-11. PMID: 2919673.
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    224. Van Voorhis K, Said HM, Ghishan FK, Abumrad NN. Transport of glutamine in rat intestinal brush-border membrane vesicles. Biochim Biophys Acta. 1989 Jan 16; 978(1):51-5. PMID: 2492432.
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    225. Said HM, Redha R, Nylander W. Biotin transport in the human intestine: inhibition by anticonvulsant drugs. Am J Clin Nutr. 1989 Jan; 49(1):127-31. PMID: 2911998.
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    226. Said HM, Van Voorhis K, Ghishan FK, Abumurad N, Nylander W, Redha R. Transport characteristics of glutamine in human intestinal brush-border membrane vesicles. Am J Physiol. 1989 Jan; 256(1 Pt 1):G240-5. PMID: 2492158.
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    227. Barbari A, Vaziri ND, Benavides I, Chen YT, Said H, Pahl MV. Intestinal transport of pyridoxine in experimental renal failure. Life Sci. 1989; 45(7):663-9. PMID: 2770420.
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    228. Said HM, Redha R. Biotin transport in rat intestinal brush-border membrane vesicles. Biochim Biophys Acta. 1988 Nov 22; 945(2):195-201. PMID: 3191121.
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    229. Said HM, Redha R, Nylander W. Biotin transport in the human intestine: site of maximum transport and effect of pH. Gastroenterology. 1988 Nov; 95(5):1312-7. PMID: 3169497.
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    230. Said HM, Ong D, Redha R. Intestinal uptake of retinol in suckling rats: characteristics and ontogeny. Pediatr Res. 1988 Oct; 24(4):481-5. PMID: 3174293.
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    231. Said HM, Ghishan FK, Redha R. Transport of glycyl-L-proline in intestinal brush-border membrane vesicles of the suckling rat: characteristics and maturation. Biochim Biophys Acta. 1988 Jun 22; 941(2):232-40. PMID: 3382647.
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    232. Said HM, Redha R, Nylander W. Biotin transport in basolateral membrane vesicles of human intestine. Gastroenterology. 1988 May; 94(5 Pt 1):1157-63. PMID: 3350285.
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    233. Said HM, Redha R, Tipton W, Nylander W. Folate transport in ileal brush border-membrane vesicles following extensive resection of proximal and middle small intestine in the rat. Am J Clin Nutr. 1988 Jan; 47(1):75-9. PMID: 2892390.
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    234. Said HM, Redah R. Ontogenesis of the intestinal transport of biotin in the rat. Gastroenterology. 1988 Jan; 94(1):68-72. PMID: 3335300.
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    235. Said HM, Redha R, Nylander W. A carrier-mediated, Na+ gradient-dependent transport for biotin in human intestinal brush-border membrane vesicles. Am J Physiol. 1987 Nov; 253(5 Pt 1):G631-6. PMID: 3120597.
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    236. Said HM, Smith R, Redha R. Studies on the intestinal surface acid microclimate: developmental aspects. Pediatr Res. 1987 Nov; 22(5):497-9. PMID: 3684377.
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    237. Said HM, Redha R. A carrier-mediated transport for folate in basolateral membrane vesicles of rat small intestine. Biochem J. 1987 Oct 01; 247(1):141-6. PMID: 3689340.
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    238. Greene HL, Moore MC, Said HM, Ghishan FK, Orth DN. Intestinal glucose transport in suckling rats fed artificial milk with and without added epidermal growth factor. Pediatr Res. 1987 Apr; 21(4):404-8. PMID: 3494980.
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    239. Katz D, Hollander D, Said HM, Dadufalza V. Aging-associated increase in intestinal permeability to polyethylene glycol 900. Dig Dis Sci. 1987 Mar; 32(3):285-8. PMID: 3816482.
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    240. Said HM, Ghishan FK, Redha R. Folate transport by human intestinal brush-border membrane vesicles. Am J Physiol. 1987 Feb; 252(2 Pt 1):G229-36. PMID: 3826350.
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    241. Said HM, Greene HL, Moore MC, Ghishan FK. Developmental maturation of D-glucose active transport system in rat intestine. Digestion. 1987; 36(4):195-200. PMID: 3609499.
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    242. Said HM, Redha R. A carrier-mediated system for transport of biotin in rat intestine in vitro. Am J Physiol. 1987 Jan; 252(1 Pt 1):G52-5. PMID: 3812688.
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    243. Moore MC, Greene HL, Said HM, Ghishan FK, Orth DN. Effect of epidermal growth factor and artificial feeding in suckling rats. Pediatr Res. 1986 Dec; 20(12):1248-51. PMID: 3099252.
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    244. Said HM, Horne DW, Wagner C. Effect of human milk folate binding protein on folate intestinal transport. Arch Biochem Biophys. 1986 Nov 15; 251(1):114-20. PMID: 2878641.
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    245. Said HM, Ghishan FK, Murrell JE. Intestinal transport of 5-methyltetrahydrofolate in streptozotocin-induced diabetes mellitus in the rat. Diabetes Res. 1986 Sep; 3(7):363-7. PMID: 3780134.
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    246. Borowitz SM, Said HM, Ghishan FK. The effects of metabolic acidosis on jejunal phosphate and glucose transport in weanling rats. Pediatr Res. 1986 Aug; 20(8):763-7. PMID: 3755523.
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    247. Said HM, Blair JA, Lucas ML, Hilburn ME. Intestinal surface acid microclimate in vitro and in vivo in the rat. J Lab Clin Med. 1986 May; 107(5):420-4. PMID: 3701189.
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    248. Ghishan FK, Said HM, Wilson PC, Murrell JE, Greene HL. Intestinal transport of zinc and folic acid: a mutual inhibitory effect. Am J Clin Nutr. 1986 Feb; 43(2):258-62. PMID: 3946290.
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    249. Said HM, Hollander D. Inhibitory effect of bile salts on the enterohepatic circulation of methotrexate in the unanesthetized rat: inhibition of methotrexate intestinal absorption. Cancer Chemother Pharmacol. 1986; 16(2):121-4. PMID: 3948296.
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    250. Said HM, Strum WB. Effect of ethanol and other aliphatic alcohols on the intestinal transport of folates. Digestion. 1986; 35(3):129-35. PMID: 3781108.
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    251. Said HM, Ghishan FK, Murrell JE. Ontogenesis of intestinal transport of 5-methyltetrahydrofolate in the rat. Am J Physiol. 1985 Nov; 249(5 Pt 1):G567-71. PMID: 4061644.
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    252. Said HM, Ghishan FK, Greene HL, Hollander D. Development maturation of riboflavin intestinal transport in the rat. Pediatr Res. 1985 Nov; 19(11):1175-8. PMID: 4069826.
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    253. Will M, Barnard JA, Said HM, Ghishan FK. Fetal hydantoin syndrome: inhibition of placental folic acid transport as a potential mechanism for fetal growth retardation in the rat. Res Commun Chem Pathol Pharmacol. 1985 Apr; 48(1):91-8. PMID: 3992032.
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    254. Said HM, Hollander D. Does aging affect the intestinal transport of riboflavin? Life Sci. 1985 Jan 07; 36(1):69-73. PMID: 3965842.
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    255. Vaziri ND, Said HM, Hollander D, Barbari A, Patel N, Dang D, Kariger R. Impaired intestinal absorption of riboflavin in experimental uremia. Nephron. 1985; 41(1):26-9. PMID: 4033840.
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    256. Said HM, Strum WB, Hollander D. Inhibitory effect of unconjugated bile acids on the enterohepatic circulation of methotrexate. J Pharmacol Exp Ther. 1984 Dec; 231(3):660-4. PMID: 6502520.
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    257. Said HM, Hollander D, Strum WB. Inhibitory effect of unconjugated bile acids on the intestinal transport of 5-methyltetrahydrofolate in rat jejunum in vitro. Gut. 1984 Dec; 25(12):1376-9. PMID: 6510770.
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    258. Said HM, Hollander D, Katz D. Absorption of 5-methyltetrahydrofolate in rat jejunum with intact blood and lymphatic vessels. Biochim Biophys Acta. 1984 Sep 05; 775(3):402-8. PMID: 6466681.
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    259. Said HM, Hollander D. Does aging affect the intestinal transport of 5-methyltetrahydrofolate? Digestion. 1984; 30(4):231-5. PMID: 6510574.
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    260. Said HM, Vaziri ND, Kariger RK, Hollander D. Intestinal absorption of 5-methyltetrahydrofolate in experimental uremia. Acta Vitaminol Enzymol. 1984; 6(4):339-46. PMID: 6534176.
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    261. Said HM, Strum WB. Cyclic adenosine-3',5'-monophosphate and folate transport in rat jejunum. Biochem Biophys Res Commun. 1983 Sep 15; 115(2):756-61. PMID: 6194795.
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    262. Said HM, Strum WB. A pH-dependent, carrier-mediated system for transport of 5-methyltetrahydrofolate in rat jejunum. J Pharmacol Exp Ther. 1983 Jul; 226(1):95-9. PMID: 6864553.
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    263. Connor MJ, Blair JA, Said H. Secondary isotope effects in studies using radiolabelled folate tracers. Nature. 1980 Sep 18; 287(5779):253-4. PMID: 7432462.
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