Donovan A Argueta

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-5153
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    Nutrition-based interventions to ameliorate pain in sickle cell disease
    NIH R00AT012494Aug 10, 2026 - Jul 31, 2029
    Role: Principal Investigator
    Nutrition-based interventions to ameliorate pain in sickle cell disease
    NIH K99AT012494Apr 1, 2024 - Mar 31, 2026
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Characterization of a mouse model to study mechanisms of hemophilia A pain. Blood Adv. 2026 Jun 15. Fouda RT, Argueta DA, Goel Y, Velasco GJ, O'Daniel K, Peterson K, Zamora Z, Chumappumkal Joseph B, von Drygalski A, Gupta K. PMID: 42295153.
      View in: PubMed   Mentions:    Fields:    
    2. Simplified Procedure for Isolation and Culture of Neuronal Cells from Brains of Sickle Cell Mice. Cells. 2026 May 26; 15(11). Goel Y, Arellano MA, O'Daniel K, Argueta DA, Lomeli R, Lomeli N, Ordaz DA, Bota DA, Kumaresan V, Gupta K. PMID: 42274569; PMCID: PMC13256901.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. A novel palmitoylethanolamide formulation improves hyperalgesia and red cell instability in murine sickle cell disease. Blood Vessel Thromb Hemost. 2026 Feb; 3(1):100136. Argueta DA, Garcia NR, Mabou Tagne A, Piomelli D, Gupta K. PMID: 41695760; PMCID: PMC12905986.
      View in: PubMed   Mentions:
    4. New kid on the block: hemorphins in sickle cell disease. Pain. 2026 Feb 01; 167(2):249-250. Argueta DA, Gupta K. PMID: 41289493.
      View in: PubMed   Mentions:    Fields:    
    5. Neuroprotective, anti-inflammatory, and analgesic activity of palmitoylethanolamide in sickle cell mice. Blood Adv. 2025 Jun 24; 9(12):3056-3068. Argueta DA, Avalos B, Goel Y, Tran H, Fotio Y, Piomelli D, DiPatrizio NV, Gupta K. PMID: 40085960; PMCID: PMC12209929.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    6. Neuronal p38 MAPK Signaling Contributes to Cisplatin-Induced Peripheral Neuropathy. Antioxidants (Basel). 2025 Apr 08; 14(4). Goel Y, Argueta DA, Peterson K, Lomeli N, Bota DA, Gupta K. PMID: 40298791; PMCID: PMC12024185.
      View in: PubMed   Mentions: 3  
    7. Targeting sickle cell pathobiology and pain with novel transdermal curcumin. PNAS Nexus. 2025 Feb; 4(2):pgaf053. Goel Y, Arellano MA, Fouda RT, Garcia NR, Lomeli RA, Kerr D, Argueta DA, Gupta M, Velasco GJ, Prince R, Banerjee P, Jana S, Alayash AI, Friedman JM, Gupta K. PMID: 40007577; PMCID: PMC11854080.
      View in: PubMed   Mentions: 2  
    8. N-acetylcysteine prevents cisplatin-induced cognitive impairments in an ovarian cancer rat model. Cancer Lett. 2024 Dec 19; 611:217405. Lomeli N, Pearre DC, Lepe J, Argueta DA, Arellano MA, Ricks-Oddie JL, Gupta K, Bota DA. PMID: 39706252; PMCID: PMC12177095.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. Mast cell extracellular trap formation underlies vascular and neural injury and hyperalgesia in sickle cell disease. Life Sci Alliance. 2024 11; 7(11). Argueta DA, Tran H, Goel Y, Nguyen A, Nguyen J, Kiven SB, Chen C, Abdulla F, Vercellotti GM, Belcher JD, Gupta K. PMID: 39242155; PMCID: PMC11381676.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    10. Low-intensity transcranial focused ultrasound suppresses pain by modulating pain-processing brain circuits. Blood. 2024 09 05; 144(10):1101-1115. Kim MG, Yu K, Yeh CY, Fouda R, Argueta D, Kiven S, Ni Y, Niu X, Chen Q, Kim K, Gupta K, He B. PMID: 38976875; PMCID: PMC11406192.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    11. Red Blood Cells as Therapeutic Target to Treat Sickle Cell Disease. Antioxid Redox Signal. 2024 06; 40(16-18):1025-1049. Bhatt S, Argueta DA, Gupta K, Kundu S. PMID: 37975291.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    12. Colchicine reduces inflammation in a humanized transgenic murine model of sickle cell disease. Haematologica. 2024 01 01; 109(1):308-311. Fouda RT, Cherukury HM, Kiven SB, Garcia NR, Argueta DA, Velasco GJ, Gupta K, Roberts JD. PMID: 37534545; PMCID: PMC10772532.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    13. Assessment of gait in mice using simplified analysis tools. Res Sq. 2023 May 05. Fouda R, Argueta D, O'Daniel K, Peterson K, Sorto T, Gupta K. PMID: 37205356; PMCID: PMC10187402.
      View in: PubMed   Mentions:
    14. Cannabidiol attenuates hyperalgesia in a mouse model of sickle cell disease. Blood. 2023 01 12; 141(2):203-208. Cherukury HM, Argueta DA, Garcia N, Fouda R, Kiven S, Lei J, Sagi V, Velasco GJ, Avalos B, DiPatrizio NV, Gupta K. PMID: 36122382; PMCID: PMC9936305.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    15. Pain in Hemophilia: Unexplored Role of Oxidative Stress. Antioxidants (Basel). 2022 Jun 03; 11(6). Fouda R, Argueta DA, Gupta K. PMID: 35740010; PMCID: PMC9220316.
      View in: PubMed   Mentions: 3  
    16. Effects of Selective Breeding, Voluntary Exercise, and Sex on Endocannabinoid Levels in the Mouse Small-Intestinal Epithelium. Physiol Behav. 2022 03 01; 245:113675. Schmill MP, Thompson Z, Argueta DA, DiPatrizio NV, Garland T. PMID: 34929258.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    17. Increased 2-arachidonoyl-sn-glycerol levels normalize cortical responses to sound and improve behaviors in Fmr1 KO mice. J Neurodev Disord. 2021 10 13; 13(1):47. Pirbhoy PS, Jonak CR, Syed R, Argueta DA, Perez PA, Wiley MB, Hessamian K, Lovelace JW, Razak KA, DiPatrizio NV, Ethell IM, Binder DK. PMID: 34645383; PMCID: PMC8513313.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    18. UPLC-MS/MS Method for Analysis of Endocannabinoid and Related Lipid Metabolism in Mouse Mucosal Tissue. Front Physiol. 2021; 12:699712. Wiley MB, Perez PA, Argueta DA, Avalos B, Wood CP, DiPatrizio NV. PMID: 34335305; PMCID: PMC8317065.
      View in: PubMed   Mentions: 6  
    19. Impact of Circulating N-Acylethanolamine Levels with Clinical and Laboratory End Points in Hemodialysis Patients. Am J Nephrol. 2021; 52(1):59-68. Pai AY, Wenziger C, Streja E, Argueta DA, DiPatrizio NV, Rhee CM, Vaziri ND, Kalantar-Zadeh K, Piomelli D, Moradi H. PMID: 33601382; PMCID: PMC7987690.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. β-endorphin at the intersection of pain and cancer progression: Preclinical evidence. Neurosci Lett. 2021 01 23; 744:135601. Argueta DA, Aich A, Lei J, Kiven S, Nguyen A, Wang Y, Gu J, Zhao W, Gupta K. PMID: 33387660; PMCID: PMC7837276.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    21. Considerations for Cannabis Use to Treat Pain in Sickle Cell Disease. J Clin Med. 2020 Dec 01; 9(12). Argueta DA, Aich A, Muqolli F, Cherukury H, Sagi V, DiPatrizio NV, Gupta K. PMID: 33271850; PMCID: PMC7761429.
      View in: PubMed   Mentions: 6  
    22. Maternal transfer of environmentally relevant polybrominated diphenyl ethers (PBDEs) produces a diabetic phenotype and disrupts glucoregulatory hormones and hepatic endocannabinoids in adult mouse female offspring. Sci Rep. 2020 10 22; 10(1):18102. Kozlova EV, Chinthirla BD, Pérez PA, DiPatrizio NV, Argueta DA, Phillips AL, Stapleton HM, González GM, Krum JM, Carrillo V, Bishay AE, Basappa KR, Currás-Collazo MC. PMID: 33093533; PMCID: PMC7582149.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    23. Spatiotemporal Alterations in Gait in Humanized Transgenic Sickle Mice. Front Immunol. 2020; 11:561947. Kiven S, Wang Y, Aich A, Argueta DA, Lei J, Sagi V, Tennakoon M, Bedros SJ, Lambrecht N, Gupta K. PMID: 33178189; PMCID: PMC7593487.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    24. Cannabinoid CB1 Receptors in the Intestinal Epithelium Are Required for Acute Western-Diet Preferences in Mice. Nutrients. 2020 Sep 20; 12(9). Avalos B, Argueta DA, Perez PA, Wiley M, Wood C, DiPatrizio NV. PMID: 32962222; PMCID: PMC7551422.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    25. Integrative approaches to treating pain in sickle cell disease: Pre-clinical and clinical evidence. Complement Ther Med. 2020 Jun; 51:102394. Sagi V, Argueta DA, Kiven S, Gupta K. PMID: 32507420; PMCID: PMC7306403.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    26. A Balanced Approach for Cannabidiol Use in Chronic Pain. Front Pharmacol. 2020; 11:561. Argueta DA, Ventura CM, Kiven S, Sagi V, Gupta K. PMID: 32425793; PMCID: PMC7204604.
      View in: PubMed   Mentions: 26  
    27. Bile acid composition regulates GPR119-dependent intestinal lipid sensing and food intake regulation in mice. Gut. 2020 09; 69(9):1620-1628. Higuchi S, Ahmad TR, Argueta DA, Perez PA, Zhao C, Schwartz GJ, DiPatrizio NV, Haeusler RA. PMID: 32111630; PMCID: PMC7423635.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    28. Circulating Endocannabinoids and Mortality in Hemodialysis Patients. Am J Nephrol. 2020; 51(2):86-95. Moradi H, Park C, Streja E, Argueta DA, DiPatrizio NV, You AS, Rhee CM, Vaziri ND, Kalantar-Zadeh K, Piomelli D. PMID: 31935741; PMCID: PMC7158229.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    29. Serum Endocannabinoid Levels in Patients With End-Stage Renal Disease. J Endocr Soc. 2019 Oct 01; 3(10):1869-1880. Moradi H, Park C, Igarashi M, Streja E, Argueta DA, Soohoo M, Daglian J, You AS, Rhee CM, Kashyap ML, DiPatrizio NV, Vaziri ND, Kalantar-Zadeh K, Piomelli D. PMID: 31583368; PMCID: PMC6767629.
      View in: PubMed   Mentions: 11  
    30. Cannabinoid CB1 Receptors Inhibit Gut-Brain Satiation Signaling in Diet-Induced Obesity. Front Physiol. 2019; 10:704. Argueta DA, Perez PA, Makriyannis A, DiPatrizio NV. PMID: 31281260; PMCID: PMC6597959.
      View in: PubMed   Mentions: 32  
    31. Endocannabinoid System and the Kidneys: From Renal Physiology to Injury and Disease. Cannabis Cannabinoid Res. 2019; 4(1):10-20. Chua JT, Argueta DA, DiPatrizio NV, Kovesdy CP, Vaziri ND, Kalantar-Zadeh K, Moradi H. PMID: 31346545; PMCID: PMC6653784.
      View in: PubMed   Mentions: 24     Fields:    
    32. Host- and Helminth-Derived Endocannabinoids That Have Effects on Host Immunity Are Generated during Infection. Infect Immun. 2018 11; 86(11). Batugedara HM, Argueta D, Jang JC, Lu D, Macchietto M, Kaur J, Ge S, Dillman AR, DiPatrizio NV, Nair MG. PMID: 30104215; PMCID: PMC6204704.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    33. Plasma fatty acid ethanolamides are associated with postprandial triglycerides, ApoCIII, and ApoE in humans consuming a high-fructose corn syrup-sweetened beverage. Am J Physiol Endocrinol Metab. 2018 08 01; 315(2):E141-E149. Price CA, Argueta DA, Medici V, Bremer AA, Lee V, Nunez MV, Chen GX, Keim NL, Havel PJ, Stanhope KL, DiPatrizio NV. PMID: 29634315; PMCID: PMC6335011.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. Plasma endocannabinoid levels in lean, overweight, and obese humans: relationships to intestinal permeability markers, inflammation, and incretin secretion. Am J Physiol Endocrinol Metab. 2018 10 01; 315(4):E489-E495. Little TJ, Cvijanovic N, DiPatrizio NV, Argueta DA, Rayner CK, Feinle-Bisset C, Young RL. PMID: 29438631; PMCID: PMC6230711.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    35. Identification of a Widespread Palmitoylethanolamide Contamination in Standard Laboratory Glassware. Cannabis Cannabinoid Res. 2017; 2(1):123-132. Angelini R, Argueta DA, Piomelli D, DiPatrizio NV. PMID: 28861512; PMCID: PMC5510777.
      View in: PubMed   Mentions: 10     Fields:    
    36. Transient Cannabinoid Receptor 2 Blockade during Immunization Heightens Intensity and Breadth of Antigen-specific Antibody Responses in Young and Aged mice. Sci Rep. 2017 02 17; 7:42584. Dotsey E, Ushach I, Pone E, Nakajima R, Jasinskas A, Argueta DA, Dillon A, DiPatrizio N, Davies H, Zlotnik A, Crompton PD, Felgner PL. PMID: 28209996; PMCID: PMC5314369.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCellsPHPublic Health
    37. Peripheral endocannabinoid signaling controls hyperphagia in western diet-induced obesity. Physiol Behav. 2017 03 15; 171:32-39. Argueta DA, DiPatrizio NV. PMID: 28065722; PMCID: PMC5296283.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    38. Circulating levels of endocannabinoids respond acutely to voluntary exercise, are altered in mice selectively bred for high voluntary wheel running, and differ between the sexes. Physiol Behav. 2017 03 01; 170:141-150. Thompson Z, Argueta D, Garland T, DiPatrizio N. PMID: 28017680; PMCID: PMC5305303.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
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