Kalpna Gupta

Title(s)Professor In Residence, Medicine
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
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    Targeting p38/JNK MAPK to ameliorate cisplatin-induced adverse sequelae on the nervous system
    NIH R01CA263806Jul 1, 2021 - Jun 30, 2026
    Role: Co-Principal Investigator
    Summer Mentoring and Research Training (SMART)
    NIH T35DK128788Apr 1, 2021 - Mar 31, 2026
    Role: Principal Investigator
    Targeting mechanisms contributing to vascular dysfunction and pain in sickle cell disease
    NIH R01HL147562Apr 4, 2019 - Mar 31, 2023
    Role: Principal Investigator
    Cannabinoid-based therapy and approaches to quantify pain in sickle cell disease
    NIH U01HL117664Aug 15, 2013 - May 31, 2019
    Role: Principal Investigator
    Characteristics and mechanisms of pain in sickle cell disease
    NIH R01HL103733Sep 5, 2010 - Aug 31, 2016
    Role: Principal Investigator
    Opioid and Breast Cancer Growth and Metastasis
    NIH R01CA109582Apr 1, 2005 - Feb 29, 2012
    Role: Principal Investigator
    Opioid Activity in Endothelium in Sickle Cell Disease
    NIH R01HL068802Apr 1, 2002 - May 31, 2014
    Role: Principal Investigator
    Cannabinoid Modulation of Hyperalgesia
    NIH R01HL135895Feb 3, 2000 - Jun 30, 2021
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. N-acetylcysteine prevents cisplatin-induced cognitive impairments in an ovarian cancer rat model. Cancer Lett. 2024 Dec 18; 217405. Lomeli N, Pearre DC, Lepe J, Argueta DA, Arellano MA, Ricks-Oddie JL, Gupta K, Bota DA. PMID: 39706252.
      View in: PubMed   Mentions:    Fields:    
    2. Sickle cell disease in India: the journey and hope for the future. Hematology Am Soc Hematol Educ Program. 2024 12 06; 2024(1):1-9. Gupta K, Krishnamurti L, Jain D. PMID: 39644008.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    3. Δ9-Tetrahydrocannabinol Alleviates Hyperalgesia in a Humanized Mouse Model of Sickle Cell Disease. J Pharmacol Exp Ther. 2024 Oct 18; 391(2):174-181. Mabou Tagne A, Fotio Y, Gupta K, Piomelli D. PMID: 38955494.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. Mast cell extracellular trap formation underlies vascular and neural injury and hyperalgesia in sickle cell disease. Life Sci Alliance. 2024 Nov; 7(11). Argueta DA, Tran H, Goel Y, Nguyen A, Nguyen J, Kiven SB, Chen C, Abdulla F, Vercellotti GM, Belcher JD, Gupta K. PMID: 39242155; PMCID: PMC11381676.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Low-intensity transcranial focused ultrasound suppresses pain by modulating pain-processing brain circuits. Blood. 2024 09 05; 144(10):1101-1115. Kim MG, Yu K, Yeh CY, Fouda R, Argueta D, Kiven S, Ni Y, Niu X, Chen Q, Kim K, Gupta K, He B. PMID: 38976875; PMCID: PMC11406192.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    6. Sickle cell disease in India: current status and progress. Lancet Haematol. 2024 May; 11(5):e322-e323. Jain D, Gupta M, Madkaikar M, Jena RK, Khargekar N, Saraf SL, Krishnamurti L, Gupta K. PMID: 38701819.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Red Blood Cells as Therapeutic Target to Treat Sickle Cell Disease. Antioxid Redox Signal. 2024 06; 40(16-18):1025-1049. Bhatt S, Argueta DA, Gupta K, Kundu S. PMID: 37975291.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. Colchicine reduces inflammation in a humanized transgenic murine model of sickle cell disease. Haematologica. 2024 01 01; 109(1):308-311. Fouda RT, Cherukury HM, Kiven SB, Garcia NR, Argueta DA, Velasco GJ, Gupta K, Roberts JD. PMID: 37534545; PMCID: PMC10772532.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    9. Cold exposure induces vaso-occlusion and pain in sickle mice that depend on complement activation. Blood. 2023 11 30; 142(22):1918-1927. Ivy ZK, Belcher JD, Khasabova IA, Chen C, Juliette JP, Abdulla F, Ruan C, Allen K, Nguyen J, Rogness VM, Beckman JD, Khasabov SG, Gupta K, Taylor RP, Simone DA, Vercellotti GM. PMID: 37774369; PMCID: PMC10731576.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    10. Crosstalk of Mast Cells and Natural Killer Cells with Neurons in Chemotherapy-Induced Peripheral Neuropathy. Int J Mol Sci. 2023 Aug 08; 24(16). Yun HD, Goel Y, Gupta K. PMID: 37628724; PMCID: PMC10454469.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Descending Facilitation of Nociceptive Transmission From the Rostral Ventromedial Medulla Contributes to Hyperalgesia in Mice with Sickle Cell Disease. Neuroscience. 2023 08 21; 526:1-12. Rogness VM, Juliette J, Khasabova IA, Gupta K, Khasabov SG, Simone DA. PMID: 37330194; PMCID: PMC10528639.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    12. Assessment of gait in mice using simplified analysis tools. Res Sq. 2023 May 05. Fouda R, Argueta D, O'Daniel K, Peterson K, Sorto T, Gupta K. PMID: 37205356; PMCID: PMC10187402.
      View in: PubMed   Mentions:
    13. Inhibition of DAGLβ as a therapeutic target for pain in sickle cell disease. Haematologica. 2023 03 01; 108(3):859-869. Khasabova IA, Gable J, Johns M, Khasabov SG, Kalyuzhny AE, Golovko MY, Golovko SA, Kiven S, Gupta K, Seybold VS, Simone DA. PMID: 35615929; PMCID: PMC9973472.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    14. Cannabidiol attenuates hyperalgesia in a mouse model of sickle cell disease. Blood. 2023 01 12; 141(2):203-208. Cherukury HM, Argueta DA, Garcia N, Fouda R, Kiven S, Lei J, Sagi V, Velasco GJ, Avalos B, DiPatrizio NV, Gupta K. PMID: 36122382; PMCID: PMC9936305.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    15. A model of painful vaso-occlusive crisis in mice with sickle cell disease. Blood. 2022 10 20; 140(16):1826-1830. Khasabova II, Juliette J, Rogness VM, Khasabov SG, Golovko MY, Golovko SA, Kiven S, Gupta K, Belcher JD, Vercellotti GM, Seybold VS, Simone DA. PMID: 35960856; PMCID: PMC9837430.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    16. Development and characterization of a preclinical total marrow irradiation conditioning-based bone marrow transplant model for sickle cell disease. Front Oncol. 2022; 12:969429. Sargur Madabushi S, Fouda R, Ghimire H, Abdelhamid AMH, Lim JE, Vishwasrao P, Kiven S, Brooks J, Zuro D, Rosenthal J, Guha C, Gupta K, Hui SK. PMID: 36147914; PMCID: PMC9485604.
      View in: PubMed   Mentions: 2  
    17. Pain in Hemophilia: Unexplored Role of Oxidative Stress. Antioxidants (Basel). 2022 Jun 03; 11(6). Fouda R, Argueta DA, Gupta K. PMID: 35740010; PMCID: PMC9220316.
      View in: PubMed   Mentions: 2  
    18. Endoplasmic Reticulum Stress in Chemotherapy-Induced Peripheral Neuropathy: Emerging Role of Phytochemicals. Antioxidants (Basel). 2022 Jan 28; 11(2). Goel Y, Fouda R, Gupta K. PMID: 35204148; PMCID: PMC8868275.
      View in: PubMed   Mentions: 5  
    19. Pain in sickle cell disease: current and potential translational therapies. Transl Res. 2021 08; 234:141-158. Sagi V, Mittal A, Tran H, Gupta K. PMID: 33711512; PMCID: PMC8217144.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    20. Cognitive complications of cancer and cancer-related treatments - Novel paradigms. Neurosci Lett. 2021 04 01; 749:135720. Lomeli N, Lepe J, Gupta K, Bota DA. PMID: 33582187; PMCID: PMC8423125.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    21. Diet and companionship modulate pain via a serotonergic mechanism. Sci Rep. 2021 02 01; 11(1):2330. Tran H, Sagi V, Jarrett S, Palzer EF, Badgaiyan RD, Gupta K. PMID: 33526805; PMCID: PMC7851147.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    22. β-endorphin at the intersection of pain and cancer progression: Preclinical evidence. Neurosci Lett. 2021 01 23; 744:135601. Argueta DA, Aich A, Lei J, Kiven S, Nguyen A, Wang Y, Gu J, Zhao W, Gupta K. PMID: 33387660; PMCID: PMC7837276.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    23. Considerations for Cannabis Use to Treat Pain in Sickle Cell Disease. J Clin Med. 2020 Dec 01; 9(12). Argueta DA, Aich A, Muqolli F, Cherukury H, Sagi V, DiPatrizio NV, Gupta K. PMID: 33271850; PMCID: PMC7761429.
      View in: PubMed   Mentions: 5  
    24. Spatiotemporal Alterations in Gait in Humanized Transgenic Sickle Mice. Front Immunol. 2020; 11:561947. Kiven S, Wang Y, Aich A, Argueta DA, Lei J, Sagi V, Tennakoon M, Bedros SJ, Lambrecht N, Gupta K. PMID: 33178189; PMCID: PMC7593487.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    25. Self-Assembled 3D Nanosplit Rings for Plasmon-Enhanced Optofluidic Sensing. Nano Lett. 2020 09 09; 20(9):6697-6705. Dai C, Lin Z, Agarwal K, Mikhael C, Aich A, Gupta K, Cho JH. PMID: 32808792.
      View in: PubMed   Mentions: 4     Fields:    
    26. Heme Causes Pain in Sickle Mice via Toll-Like Receptor 4-Mediated Reactive Oxygen Species- and Endoplasmic Reticulum Stress-Induced Glial Activation. Antioxid Redox Signal. 2021 02 01; 34(4):279-293. Lei J, Paul J, Wang Y, Gupta M, Vang D, Thompson S, Jha R, Nguyen J, Valverde Y, Lamarre Y, Jones MK, Gupta K. PMID: 32729340; PMCID: PMC7821434.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    27. Effect of Inhaled Cannabis for Pain in Adults With Sickle Cell Disease: A Randomized Clinical Trial. JAMA Netw Open. 2020 07 01; 3(7):e2010874. Abrams DI, Couey P, Dixit N, Sagi V, Hagar W, Vichinsky E, Kelly ME, Connett JE, Gupta K. PMID: 32678452; PMCID: PMC7368173.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    28. Integrative approaches to treating pain in sickle cell disease: Pre-clinical and clinical evidence. Complement Ther Med. 2020 Jun; 51:102394. Sagi V, Argueta DA, Kiven S, Gupta K. PMID: 32507420; PMCID: PMC7306403.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    29. A Balanced Approach for Cannabidiol Use in Chronic Pain. Front Pharmacol. 2020; 11:561. Argueta DA, Ventura CM, Kiven S, Sagi V, Gupta K. PMID: 32425793; PMCID: PMC7204604.
      View in: PubMed   Mentions: 20  
    30. Significant Quantitative Differences in Orexin Neuronal Activation After Pain Assessments in an Animal Model of Sickle Cell Disease. Front Mol Biosci. 2020; 7:5. Richardson K, Sweatt N, Tran H, Apprey V, Uthayathas S, Taylor R, Gupta K. PMID: 32118032; PMCID: PMC7025496.
      View in: PubMed   Mentions: 2  
    31. Substance P modulates electroacupuncture analgesia in humanized mice with sickle cell disease. J Pain Res. 2019; 12:2419-2426. Wang Y, Lei J, Jha RK, Kiven S, Gupta K. PMID: 31447579; PMCID: PMC6682765.
      View in: PubMed   Mentions: 6  
    32. Pain and sickle cell disease. Curr Opin Hematol. 2019 05; 26(3):131-138. Aich A, Jones MK, Gupta K. PMID: 30893088.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    33. Morphine promotes neovascularizing retinopathy in sickle transgeneic mice. Blood Adv. 2019 04 09; 3(7):1073-1083. Gupta K, Chen C, Lutty GA, Hebbel RP. PMID: 30944099; PMCID: PMC6457224.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    34. Effect of chronic opioid therapy on pain and survival in a humanized mouse model of sickle cell disease. Blood Adv. 2019 03 26; 3(6):869-873. Tran H, Sagi V, Leonce Song-Naba W, Wang Y, Mittal A, Lamarre Y, Zhang L, Gupta K. PMID: 30885998; PMCID: PMC6436015.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    35. Mast Cell Neural Interactions in Health and Disease. Front Cell Neurosci. 2019; 13:110. Mittal A, Sagi V, Gupta M, Gupta K. PMID: 30949032; PMCID: PMC6435484.
      View in: PubMed   Mentions: 29  
    36. Sensitization of nociceptors by prostaglandin E2-glycerol contributes to hyperalgesia in mice with sickle cell disease. Blood. 2019 05 02; 133(18):1989-1998. Khasabova IA, Uhelski M, Khasabov SG, Gupta K, Seybold VS, Simone DA. PMID: 30796025; PMCID: PMC6497514.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    37. Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium. Front Cell Neurosci. 2019; 13:56. Tran H, Mittal A, Sagi V, Luk K, Nguyen A, Gupta M, Nguyen J, Lamarre Y, Lei J, Guedes A, Gupta K. PMID: 30837844; PMCID: PMC6389721.
      View in: PubMed   Mentions: 20  
    38. Diet and gender influence survival of transgenic Berkley sickle cell mice. Haematologica. 2019 08; 104(8):e331-e334. Jahagirdar OB, Mittal AM, Song-Naba WL, Jha R, Kiven SB, Thompson ST, Connett JE, Gupta K. PMID: 30765475; PMCID: PMC6669136.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    39. Immune cell neural interactions and their contributions to sickle cell disease. Neurosci Lett. 2019 04 23; 699:167-171. Sagi V, Mittal A, Gupta M, Gupta K. PMID: 30738871.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    40. Bartonella henselae Infection in Sickle Cell Disease Mice Is Associated with Hyperalgesia. Vector Borne Zoonotic Dis. 2019 Feb; 19(2):102-105. de Almeida AR, Vieira-Damiani G, da Silva MN, Lania BG, Soares TCB, Drummond MR, Lins KA, Ericson ME, Gupta K, Velho PENF. PMID: 30272535.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    41. Mouse Models of Pain in Sickle Cell Disease. Curr Protoc Neurosci. 2018 10; 85(1):e54. Sagi V, Song-Naba WL, Benson BA, Joshi SS, Gupta K. PMID: 30265442.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    42. Targeting pain at its source in sickle cell disease. Am J Physiol Regul Integr Comp Physiol. 2018 07 01; 315(1):R104-R112. Gupta K, Jahagirdar O, Gupta K. PMID: 29590553; PMCID: PMC6087885.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    43. Targeting novel mechanisms of pain in sickle cell disease. Hematology Am Soc Hematol Educ Program. 2017 12 08; 2017(1):546-555. Tran H, Gupta M, Gupta K. PMID: 29222304; PMCID: PMC6142592.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    44. Targeting novel mechanisms of pain in sickle cell disease. Blood. 2017 11 30; 130(22):2377-2385. Tran H, Gupta M, Gupta K. PMID: 29187376; PMCID: PMC5709786.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimals
    45. Sensitization of C-fiber nociceptors in mice with sickle cell disease is decreased by local inhibition of anandamide hydrolysis. Pain. 2017 Sep; 158(9):1711-1722. Uhelski ML, Gupta K, Simone DA. PMID: 28570479; PMCID: PMC5561456.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    46. A monocyte-TNF-endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade. Am J Hematol. 2017 Nov; 92(11):1119-1130. Solovey A, Somani A, Belcher JD, Milbauer L, Vincent L, Pawlinski R, Nath KA, Kelm RJ, Mackman N, O'Sullivan MG, Gupta K, Vercellotti GM, Hebbel RP. PMID: 28699284; PMCID: PMC5655742.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    47. Transcriptomic analysis of gene signatures associated with sickle pain. Sci Data. 2017 05 16; 4:170051. Paul JA, Aich A, Abrahante JE, Wang Y, LaRue RS, Rathe SK, Kalland K, Mittal A, Jha R, Peng F, Largaespada DA, Bagchi A, Gupta K. PMID: 29292796; PMCID: PMC5749120.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    48. Functional MRI BOLD response in sickle mice with hyperalgesia. Blood Cells Mol Dis. 2017 06; 65:81-85. Wang Y, Wang X, Chen W, Gupta K, Zhu XH. PMID: 28579187; PMCID: PMC5521217.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    49. Electroacupuncture in conscious free-moving mice reduces pain by ameliorating peripheral and central nociceptive mechanisms. Sci Rep. 2016 Sep 30; 6:34493. Wang Y, Lei J, Gupta M, Peng F, Lam S, Jha R, Raduenz E, Beitz AJ, Gupta K. PMID: 27687125; PMCID: PMC5043286.
      View in: PubMed   Mentions: 13     Fields:    
    50. Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia. PLoS One. 2016; 11(8):e0160608. Lei J, Benson B, Tran H, Ofori-Acquah SF, Gupta K. PMID: 27494522; PMCID: PMC4975462.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    51. Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease. Haematologica. 2016 10; 101(10):e397-e400. Nwankwo JO, Lei J, Xu J, Rivera A, Gupta K, Chishti AH. PMID: 27418647; PMCID: PMC5046659.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    52. Could Perioperative Opioid Use Increase the Risk of Cancer Progression and Metastases? Int Anesthesiol Clin. 2016; 54(4):e1-e16. Aich A, Gupta P, Gupta K. PMID: 27602710; PMCID: PMC5061339.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    53. Cannabinoid receptor-specific mechanisms to alleviate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation. Haematologica. 2016 05; 101(5):566-77. Vincent L, Vang D, Nguyen J, Benson B, Lei J, Gupta K. PMID: 26703965; PMCID: PMC5004356.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    54. Quantification of pain in sickle mice using facial expressions and body measurements. Blood Cells Mol Dis. 2016 Mar; 57:58-66. Mittal A, Gupta M, Lamarre Y, Jahagirdar B, Gupta K. PMID: 26852657; PMCID: PMC4746724.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    55. Mast Cell-Mediated Mechanisms of Nociception. Int J Mol Sci. 2015 Dec 04; 16(12):29069-92. Aich A, Afrin LB, Gupta K. PMID: 26690128; PMCID: PMC4691098.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    56. Spinal glial activation and oxidative stress are alleviated by treatment with curcumin or coenzyme Q in sickle mice. Haematologica. 2016 Feb; 101(2):e44-7. Valverde Y, Benson B, Gupta M, Gupta K. PMID: 26546503; PMCID: PMC4938337.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    57. Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice. Haematologica. 2015 Dec; 100(12):1517-25. Vang D, Paul JA, Nguyen J, Tran H, Vincent L, Yasuda D, Zaveri NT, Gupta K. PMID: 26294734; PMCID: PMC4666327.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    58. Sensitization of nociceptive spinal neurons contributes to pain in a transgenic model of sickle cell disease. Pain. 2015 Apr; 156(4):722-730. Cataldo G, Rajput S, Gupta K, Simone DA. PMID: 25630029; PMCID: PMC4366346.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    59. Dominant lethal pathologies in male mice engineered to contain an X-linked DUX4 transgene. Cell Rep. 2014 Sep 11; 8(5):1484-96. Dandapat A, Bosnakovski D, Hartweck LM, Arpke RW, Baltgalvis KA, Vang D, Baik J, Darabi R, Perlingeiro RC, Hamra FK, Gupta K, Lowe DA, Kyba M. PMID: 25176645; PMCID: PMC4188423.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    60. Mast cell activation contributes to sickle cell pathobiology and pain in mice. Blood. 2013 Sep 12; 122(11):1853-62. Vincent L, Vang D, Nguyen J, Gupta M, Luk K, Ericson ME, Simone DA, Gupta K. PMID: 23775718; PMCID: PMC3772495.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansAnimalsCells
    61. Carbon-fiber microelectrode amperometry reveals sickle-cell-induced inflammation and chronic morphine effects on single mast cells. ACS Chem Biol. 2012 Mar 16; 7(3):543-51. Manning BM, Hebbel RP, Gupta K, Haynes CL. PMID: 22217155; PMCID: PMC3306545.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    62. Influence of morphine on pericyte-endothelial interaction: implications for antiangiogenic therapy. J Oncol. 2012; 2012:458385. Luk K, Boatman S, Johnson KN, Dudek OA, Ristau N, Vang D, Nguyen J, Gupta K. PMID: 22315595; PMCID: PMC3270445.
      View in: PubMed   Mentions: 19  
    63. Mouse models for studying pain in sickle disease: effects of strain, age, and acuteness. Br J Haematol. 2012 Feb; 156(4):535-44. Cain DM, Vang D, Simone DA, Hebbel RP, Gupta K. PMID: 22171826; PMCID: PMC3779783.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimals
    64. Morphine-induced epidermal growth factor pathway activation in non-small cell lung cancer. Anesth Analg. 2011 Dec; 113(6):1353-64. Fujioka N, Nguyen J, Chen C, Li Y, Pasrija T, Niehans G, Johnson KN, Gupta V, Kratzke RA, Gupta K. PMID: 22003224; PMCID: PMC3725599.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    65. CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET). J Biol Chem. 2011 May 20; 286(20):17543-59. Mitra R, Guo Z, Milani M, Mesaros C, Rodriguez M, Nguyen J, Luo X, Clarke D, Lamba J, Schuetz E, Donner DB, Puli N, Falck JR, Capdevila J, Gupta K, Blair IA, Potter DA. PMID: 21402692; PMCID: PMC3093829.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    66. Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids. Blood. 2010 Jul 22; 116(3):456-65. Kohli DR, Li Y, Khasabov SG, Gupta P, Kehl LJ, Ericson ME, Nguyen J, Gupta V, Hebbel RP, Simone DA, Gupta K. PMID: 20304807; PMCID: PMC2913454.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansAnimalsCells
    67. Morphine induces mesangial cell proliferation and glomerulopathy via kappa-opioid receptors. Am J Physiol Renal Physiol. 2008 Jun; 294(6):F1388-97. Weber ML, Farooqui M, Nguyen J, Ansonoff M, Pintar JE, Hebbel RP, Gupta K. PMID: 18385270.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    68. Morphine stimulates vascular endothelial growth factor-like signaling in mouse retinal endothelial cells. Curr Neurovasc Res. 2006 Aug; 3(3):171-80. Chen C, Farooqui M, Gupta K. PMID: 16918381.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
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