Paolo Casali

Title(s)Professor Emeritus, Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-4456
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    Collapse Research 
    Collapse Research Activities and Funding
    Graduate Research in Immunology Program (GRIP): To train graduate students for successful careers in academia, industry and government
    NIH T32AI138944Aug 13, 2018 - Jul 31, 2023
    Role: Co-Principal Investigator
    Intrinsic B cell epigenetic regulation of antibody and autoantibody responses by Sirt1
    NIH R01AI105813Jun 14, 2013 - Jan 31, 2024
    Role: Principal Investigator
    Epigenetic downregulation of the antibody response and inhibition of autoimmunity
    NIH R56AI105813Jun 14, 2013 - Jan 31, 2014
    Role: Principal Investigator
    Immunoglobulin class switch DNA recombination
    NIH R56AI045011Aug 1, 2012 - Jul 31, 2014
    Role: Principal Investigator
    Rab7 and estrogen-ER as B cell-intrinsic mediators of auto/antibody responses
    NIH R01AI079705Jul 1, 2008 - Nov 30, 2020
    Role: Principal Investigator
    Molecular mechanisms in the generation of autoantibodies and lupus
    NIH R56AI079705Jul 1, 2008 - Dec 14, 2009
    Role: Principal Investigator
    Immunology Research Training Grant
    NIH T32AI060573Jul 1, 2004 - Jul 31, 2021
    Role: Co-Principal Investigator
    Immunoglobulin class switch DNA recombination
    NIH R01AI045011May 1, 2000 - Jul 31, 2012
    Role: Principal Investigator
    Immunology and Microbial Pathogenesis Research Training Program
    NIH T32AI007621Sep 1, 1999 - Aug 31, 2016
    Role: Co-Principal Investigator
    AGING--ANTIBODY RESPONSE TO BACTERIAL AND VIRAL AGS
    NIH R01AG013910Aug 15, 1997 - Jul 31, 2003
    Role: Principal Investigator
    MOLECULAR IMMUNOBIOLOGY OF AIDS-LYMPHOMA
    NIH R01CA068541Jan 19, 1995 - Dec 31, 1998
    Role: Principal Investigator
    HUMAN ANTIBODY V GENES--GENOMIC ORGANIZATION/EXPRESSION
    NIH R13AI036255Jul 1, 1994 - Jun 30, 1995
    Role: Principal Investigator
    SOMATIC HYPERMUTATION IN HUMAN B CELLS
    NIH R01AR040908Feb 1, 1992 - Jul 31, 2008
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Management of serious complications in intra-abdominal desmoid-type fibromatosis. Cancer Rep (Hoboken). 2021 Jun 24; e1411. Bini F, Fiore M, Provenzano S, Bertulli R, Ottini A, Colombo C, Vitellaro M, Greco G, Morosi C, Gronchi A, Casali PG, Palassini E. PMID: 34165246.
      View in: PubMed   Mentions:
    2. Magnetic resonance imaging patterns of tumor response to chemotherapy in desmoid-type fibromatosis. Cancer Med. 2021 Jul; 10(13):4356-4365. Zanchetta E, Ciniselli CM, Bardelli A, Colombo C, Stacchiotti S, Baldi GG, Provenzano S, Bertulli R, Bini F, Casale A, Greco FG, Ferrari A, Verderio P, Fiore M, Gronchi A, Casali PG, Morosi C, Palassini E. PMID: 34102009.
      View in: PubMed   Mentions:    Fields:    
    3. Outcome in dedifferentiated chondrosarcoma for patients treated with multimodal therapy: Results from the EUROpean Bone Over 40 Sarcoma Study. Eur J Cancer. 2021 Jul; 151:150-158. Hompland I, Ferrari S, Bielack S, Palmerini E, Hall KS, Picci P, Hecker-Nolting S, Donati DM, Blattmann C, Bjerkehagen B, Staals E, Kager L, Gambarotti M, Kühne T, Eriksson M, Ferraresi V, Kevric M, Biagini R, Baumhoer D, Brosjø O, Comandone A, Schwarz R, Bertulli R, Kessler T, Hansson L, Apice G, Heydrich BN, Setola E, Flörcken A, Ruggieri P, Krasniqi F, Hofmann-Wackersreuther G, Casali P, Reichardt P, Smeland S. PMID: 33990016.
      View in: PubMed   Mentions:    Fields:    
    4. Ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society community of experts on the incidence threshold and the list of entities. Cancer. 2021 Aug 15; 127(16):2934-2942. Stacchiotti S, Frezza AM, Blay JY, Baldini EH, Bonvalot S, Bovée JVMG, Callegaro D, Casali PG, Chiang RC, Demetri GD, Demicco EG, Desai J, Eriksson M, Gelderblom H, George S, Gounder MM, Gronchi A, Gupta A, Haas RL, Hayes-Jardon A, Hohenberger P, Jones KB, Jones RL, Kasper B, Kawai A, Kirsch DG, Kleinerman ES, Le Cesne A, Lim J, Chirlaque López MD, Maestro R, Marcos-Gragera R, Martin Broto J, Matsuda T, Mir O, Patel SR, Raut CP, Razak ARA, Reed DR, Rutkowski P, Sanfilippo RG, Sbaraglia M, Schaefer IM, Strauss DC, Sundby Hall K, Tap WD, Thomas DM, van der Graaf WTA, van Houdt WJ, Visser O, von Mehren M, Wagner AJ, Wilky BA, Won YJ, Fletcher CDM, Dei Tos AP, Trama A. PMID: 33910263.
      View in: PubMed   Mentions:    Fields:    
    5. Impact of Pathological Stratification on the Clinical Outcomes of Advanced Well-Differentiated/Dedifferentiated Liposarcoma Treated with Trabectedin. Cancers (Basel). 2021 Mar 22; 13(6). Fabbroni C, Fucà G, Ligorio F, Fumagalli E, Barisella M, Collini P, Morosi C, Gronchi A, Dei Tos AP, Casali PG, Sanfilippo R. PMID: 33810165.
      View in: PubMed   Mentions:
    6. Systemic therapies in advanced epithelioid haemangioendothelioma: A retrospective international case series from the World Sarcoma Network and a review of literature. Cancer Med. 2021 04; 10(8):2645-2659. Frezza AM, Ravi V, Lo Vullo S, Vincenzi B, Tolomeo F, Chen TW, Teterycz P, Baldi GG, Italiano A, Penel N, Brunello A, Duffaud F, Hindi N, Iwata S, Smrke A, Fedenko A, Gelderblom H, Van Der Graaf W, Vozy A, Connolly E, Grassi M, Benjamin RS, Broto JM, Grignani G, Jones RL, Kawai A, Tysarowski A, Mariani L, Casali PG, Stacchiotti S. PMID: 33713582.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Selinexor versus doxorubicin in dedifferentiated liposarcoma PDXs: evidence of greater activity and apoptotic response dependent on p53 nuclear accumulation and survivin down-regulation. J Exp Clin Cancer Res. 2021 Mar 01; 40(1):83. Zuco V, Pasquali S, Tortoreto M, Brich S, Percio S, Dagrada GP, Colombo C, Sanfilippo R, Lauricella C, Gounder M, El Bezawy R, Barisella M, Dei Tos AP, Casali PG, Gronchi A, Stacchiotti S, Zaffaroni N. PMID: 33648535.
      View in: PubMed   Mentions:    Fields:    
    8. Unplanned Excision of Extremity and Trunk Wall Soft Tissue Sarcoma: To Re-resect or Not to Re-resect? Ann Surg Oncol. 2021 Aug; 28(8):4706-4717. Danieli M, Barretta F, Fiore M, Radaelli S, Sangalli C, Barisella M, Stacchiotti S, Palassini E, Miceli R, Callegaro D, Casali PG, Gronchi A. PMID: 33511543.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Corrigendum to "Italian consensus conference on management of uterine sarcomas on behalf of S.I.G.O. (Societa' italiana di Ginecologia E Ostetricia)" [Eur J Canc. vol. 139 November (2020) Pages 149-168]. Eur J Cancer. 2021 Feb; 144:397-398. Ferrandina G, Aristei C, Biondetti PR, Cananzi FCM, Casali P, Ciccarone F, Colombo N, Comandone A, Corvo' R, De Iaco P, Dei Tos AP, Donato V, Fiore M, Franchi , Gadducci A, Gronchi A, Guerriero S, Infante A, Odicino F, Pirronti T, Quagliuolo V, Sanfilippo R, Testa AC, Zannoni GF, Scambia G, Lorusso D. PMID: 33353792.
      View in: PubMed   Mentions:    Fields:    
    10. Evaluating the effectiveness of clinical ethics committees: a systematic review. Med Health Care Philos. 2021 Mar; 24(1):135-151. Crico C, Sanchini V, Casali PG, Pravettoni G. PMID: 33219898.
      View in: PubMed   Mentions: 1     Fields:    
    11. Epigenetics of the antibody and autoantibody response. Curr Opin Immunol. 2020 12; 67:75-86. Moroney JB, Chupp DP, Xu Z, Zan H, Casali P. PMID: 33176228.
      View in: PubMed   Mentions: 1     Fields:    
    12. Integrative transcriptome and chromatin landscape analysis reveals distinct epigenetic regulations in human memory B cells. Nat Commun. 2020 10 28; 11(1):5435. Moroney JB, Vasudev A, Pertsemlidis A, Zan H, Casali P. PMID: 33116135.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    13. Activity of sirolimus in patients with progressive epithelioid hemangioendothelioma: A case-series analysis within the Italian Rare Cancer Network. Cancer. 2021 Feb 15; 127(4):569-576. Stacchiotti S, Simeone N, Lo Vullo S, Baldi GG, Brunello A, Vincenzi B, Palassini E, Dagrada G, Collini P, Morosi C, Greco FG, Sbaraglia M, Dei Tos AP, Mariani L, Frezza AM, Casali PG. PMID: 33107985.
      View in: PubMed   Mentions: 4     Fields:    
    14. In Reply. Oncologist. 2020 12; 25(12):e2018. Stacchiotti S, Baldi GG, Casali PG. PMID: 32918787.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Italian consensus conference on management of uterine sarcomas on behalf of S.I.G.O. (Societa' italiana di Ginecologia E Ostetricia). Eur J Cancer. 2020 11; 139:149-168. Ferrandina G, Aristei C, Biondetti PR, Cananzi FCM, Casali P, Ciccarone F, Colombo N, Comandone A, Corvo' R, De Iaco P, Dei Tos AP, Donato V, Fiore M, Franchi , Gadducci A, Gronchi A, Guerriero S, Infante A, Odicino F, Pirronti T, Quagliuolo V, Sanfilippo R, Testa AC, Zannoni GF, Scambia G, Lorusso D. PMID: 32992154.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. When does a new sarcoma exist? Clin Sarcoma Res. 2020; 10:19. Casali PG, Dei Tos AP, Gronchi A. PMID: 32944215.
      View in: PubMed   Mentions:
    17. Anthracycline-based and gemcitabine-based chemotherapy in the adjuvant setting for stage I uterine leiomyosarcoma: a retrospective analysis at two reference centers. Clin Sarcoma Res. 2020; 10:17. Fucà G, Fabbroni C, Mancari R, Manglaviti S, Bogani G, Fumagalli E, Bertulli R, Morosi C, Collini P, Raspagliesi F, Colombo N, Casali PG, Sanfilippo R. PMID: 32874547.
      View in: PubMed   Mentions:
    18. The Activity of Chemotherapy in Inflammatory Myofibroblastic Tumors: A Multicenter, European Retrospective Case Series Analysis. Oncologist. 2020 11; 25(11):e1777-e1784. Baldi GG, Brahmi M, Lo Vullo S, Cojocaru E, Mir O, Casanova M, Vincenzi B, De Pas TM, Grignani G, Pantaleo MA, Blay JY, Jones RL, Le Cesne A, Frezza AM, Gronchi A, Collini P, Dei Tos AP, Morosi C, Mariani L, Casali PG, Stacchiotti S. PMID: 32584482.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Rechallenge of denosumab in jaw osteonecrosis of patients with unresectable giant cell tumour of bone: a case series analysis and literature review. ESMO Open. 2020 07; 5(4). Raimondi A, Simeone N, Guzzo M, Maniezzo M, Collini P, Morosi C, Greco FG, Frezza AM, Casali PG, Stacchiotti S. PMID: 32661185.
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    20. Addition of Antiestrogen Treatment in Patients with Malignant PEComa Progressing to mTOR Inhibitors. Clin Cancer Res. 2020 10 15; 26(20):5534-5538. Sanfilippo R, Fabbroni C, Fucà G, Fumagalli E, Morosi C, Sbaraglia M, Gronchi A, Collini P, Dei Tos AP, Casali PG. PMID: 32605908.
      View in: PubMed   Mentions: 5     Fields:    
    21. A randomized double-blind phase II study evaluating the role of maintenance therapy with cabozantinib in high-grade uterine sarcoma after stabilization or response to doxorubicin ± ifosfamide following surgery or in metastatic first line treatment (EORTC62113). Int J Gynecol Cancer. 2020 10; 30(10):1633-1637. Ray-Coquard I, Hatcher H, Bompas E, Casado A, Westermann A, Isambert N, Casali PG, Pratap S, Stark D, Valverde C, Anand A, Huizing M, Floquet A, Lindner L, Hermes B, Seddon B, Coens C, Jones R, Reed N. PMID: 32546554.
      View in: PubMed   Mentions: 1     Fields:    
    22. Quality of Surgery and Outcome in Localized Gastrointestinal Stromal Tumors Treated Within an International Intergroup Randomized Clinical Trial of Adjuvant Imatinib. JAMA Surg. 2020 06 01; 155(6):e200397. Gronchi A, Bonvalot S, Poveda Velasco A, Kotasek D, Rutkowski P, Hohenberger P, Fumagalli E, Judson IR, Italiano A, Gelderblom HJ, van Coevorden F, Penel N, Kopp HG, Duffaud F, Goldstein D, Broto JM, Wardelmann E, Marréaud S, Smithers M, Le Cesne A, Zaffaroni F, Litière S, Blay JY, Casali PG. PMID: 32236507.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    23. Neoadjuvant Chemotherapy in High-Risk Soft Tissue Sarcomas: Final Results of a Randomized Trial From Italian (ISG), Spanish (GEIS), French (FSG), and Polish (PSG) Sarcoma Groups. J Clin Oncol. 2020 07 01; 38(19):2178-2186. Gronchi A, Palmerini E, Quagliuolo V, Martin Broto J, Lopez Pousa A, Grignani G, Brunello A, Blay JY, Tendero O, Diaz Beveridge R, Ferraresi V, Lugowska I, Merlo DF, Fontana V, Marchesi E, Braglia L, Donati DM, Palassini E, Bianchi G, Marrari A, Morosi C, Stacchiotti S, Bagué S, Coindre JM, Dei Tos AP, Picci P, Bruzzi P, Casali PG. PMID: 32421444.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    24. Correction: B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-?B Activation for Antibody Class-Switching. J Immunol. 2020 Jun 01; 204(11):3058. Yan H, Fernandez M, Wang J, Wu S, Wang R, Lou Z, Moroney JB, Rivera CE, Taylor JR, Gan H, Zan H, Kovalskyy D, Liu D, Casali P, Xu Z. PMID: 32277056.
      View in: PubMed   Mentions:    Fields:    
    25. The natural history of epithelioid sarcoma. A retrospective multicentre case-series within the Italian Sarcoma Group. Eur J Surg Oncol. 2020 07; 46(7):1320-1326. Frezza AM, Sbaraglia M, Lo Vullo S, Baldi GG, Simeone N, Frenos F, Campanacci D, Stacchiotti S, Pasquali S, Callegaro D, Gambarotti M, Barisella M, Palomba A, Mariani L, Casali PG, Dei Tos AP, Gronchi A. PMID: 32307188.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. B cell Sirt1 deacetylates histone and non-histone proteins for epigenetic modulation of AID expression and the antibody response. Sci Adv. 2020 04; 6(14):eaay2793. Gan H, Shen T, Chupp DP, Taylor JR, Sanchez HN, Li X, Xu Z, Zan H, Casali P. PMID: 32270032.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    27. Estrogen Reverses HDAC Inhibitor-Mediated Repression of Aicda and Class-Switching in Antibody and Autoantibody Responses by Downregulation of miR-26a. Front Immunol. 2020; 11:491. Casali P, Shen T, Xu Y, Qiu Z, Chupp DP, Im J, Xu Z, Zan H. PMID: 32265934.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    28. Correction: Combination of PPAR? Agonist Pioglitazone and Trabectedin Induce Adipocyte Differentiation to Overcome Trabectedin Resistance in Myxoid Liposarcomas. Clin Cancer Res. 2020 Mar 01; 26(5):1199. Frapolli R, Bello E, Ponzo M, Craparotta I, Mannarino L, Ballabio S, Marchini S, Carrassa L, Ubezio P, Porcu L, Brich S, Sanfilippo R, Casali PG, Gronchi A, Pilotti S, D'Incalci M. PMID: 32122930.
      View in: PubMed   Mentions:    Fields:    
    29. Current models, challenges and best practices for work conducted between European academic cooperative groups and industry. ESMO Open. 2020 03; 5(2). Stahel RA, Lacombe D, Cardoso F, Casali PG, Negrouk A, Marais R, Hiltbrunner A, Vyas M, Clinical Academic Cancer Research Forum (CAREFOR) . PMID: 32213534.
      View in: PubMed   Mentions:
    30. Rationale of the rare cancer list: a consensus paper from the Joint Action on Rare Cancers (JARC) of the European Union (EU). ESMO Open. 2020 03; 5(2). Casali PG, Trama A. PMID: 32220947.
      View in: PubMed   Mentions:
    31. Correction: Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin. Br J Cancer. 2020 Mar; 122(7):1120. Bello E, Brich S, Craparotta I, Mannarino L, Ballabio S, Gatta R, Marchini S, Carrassa L, Matteo C, Sanfilippo R, Gronchi A, Casali PG, Pilotti S, D'Incalci M, Frapolli R. PMID: 32047297.
      View in: PubMed   Mentions:    Fields:    
    32. Pazopanib for treatment of typical solitary fibrous tumours: a multicentre, single-arm, phase 2 trial. Lancet Oncol. 2020 03; 21(3):456-466. Martin-Broto J, Cruz J, Penel N, Le Cesne A, Hindi N, Luna P, Moura DS, Bernabeu D, de Alava E, Lopez-Guerrero JA, Dopazo J, Peña-Chilet M, Gutierrez A, Collini P, Karanian M, Redondo A, Lopez-Pousa A, Grignani G, Diaz-Martin J, Marcilla D, Fernandez-Serra A, Gonzalez-Aguilera C, Casali PG, Blay JY, Stacchiotti S. PMID: 32066540.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    33. B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-?B Activation for Antibody Class-Switching. J Immunol. 2020 03 01; 204(5):1146-1157. Yan H, Fernandez M, Wang J, Wu S, Wang R, Lou Z, Moroney JB, Rivera CE, Taylor JR, Gan H, Zan H, Kolvaskyy D, Liu D, Casali P, Xu Z. PMID: 31932498.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    34. B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids. Nat Commun. 2020 01 02; 11(1):60. Sanchez HN, Moroney JB, Gan H, Shen T, Im JL, Li T, Taylor JR, Zan H, Casali P. PMID: 31896754.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    35. Development and external validation of a dynamic prognostic nomogram for primary extremity soft tissue sarcoma survivors. EClinicalMedicine. 2019 Dec; 17:100215. Callegaro D, Miceli R, Bonvalot S, Ferguson PC, Strauss DC, van Praag VVM, Levy A, Griffin AM, Hayes AJ, Stacchiotti S, Pèchoux CL, Smith MJ, Fiore M, Tos APD, Smith HG, Catton C, Szkandera J, Leithner A, van de Sande MAJ, Casali PG, Wunder JS, Gronchi A. PMID: 31891146.
      View in: PubMed   Mentions:
    36. Systemic treatments in MDM2 positive intimal sarcoma: A multicentre experience with anthracycline, gemcitabine, and pazopanib within the World Sarcoma Network. Cancer. 2020 01 01; 126(1):98-104. Frezza AM, Assi T, Lo Vullo S, Ben-Ami E, Dufresne A, Yonemori K, Noguchi E, Siontis B, Ferraro R, Teterycz P, Duffaud F, Ravi V, Vincenzi B, Gelderblom H, Pantaleo MA, Baldi GG, Desar I, Fedenko A, Maki RG, Jones RL, Benjamin RS, Blay JY, Kawai A, Gounder M, Gronchi A, Le Cesne A, Mir O, Czarnecka AM, Schuetze S, Wagner AJ, Adam J, Barisella M, Sbaraglia M, Hornick JL, Meurgey A, Mariani L, Casali PG, Thornton K, Stacchiotti S. PMID: 31536651.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    37. Combination of PPAR? Agonist Pioglitazone and Trabectedin Induce Adipocyte Differentiation to Overcome Trabectedin Resistance in Myxoid Liposarcomas. Clin Cancer Res. 2019 12 15; 25(24):7565-7575. Frapolli R, Bello E, Ponzo M, Craparotta I, Mannarino L, Ballabio S, Marchini S, Carrassa L, Ubezio P, Porcu L, Brich S, Sanfilippo R, Casali PG, Gronchi A, Pilotti S, D'Incalci M. PMID: 31481505.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    38. Quality of surgery and surgical reporting for patients with primary gastrointestinal stromal tumours participating in the EORTC STBSG 62024 adjuvant imatinib study. Eur J Cancer. 2019 10; 120:47-53. Hohenberger P, Bonvalot S, van Coevorden F, Rutkowski P, Stoeckle E, Olungu C, Litiere S, Wardelmann E, Gronchi A, Casali P. PMID: 31479947.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    39. Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin. Br J Cancer. 2019 09; 121(6):464-473. Bello E, Brich S, Craparotta I, Mannarino L, Ballabio S, Gatta R, Marchini S, Carrassa L, Matteo C, Sanfilippo R, Gronchi A, Casali PG, Pilotti S, D'Incalci M, Frapolli R. PMID: 31409911.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    40. Comparative Assessment of Antitumor Effects and Autophagy Induction as a Resistance Mechanism by Cytotoxics and EZH2 Inhibition in INI1-Negative Epithelioid Sarcoma Patient-Derived Xenograft. Cancers (Basel). 2019 Jul 19; 11(7). Stacchiotti S, Zuco V, Tortoreto M, Cominetti D, Frezza AM, Percio S, Indio V, Barisella M, Monti V, Brich S, Astolfi A, Colombo C, Pasquali S, Folini M, Gounder MM, Pantaleo MA, Collini P, Dei Tos AP, Casali PG, Gronchi A, Zaffaroni N. PMID: 31331120.
      View in: PubMed   Mentions:
    41. Pazopanib for treatment of advanced extraskeletal myxoid chondrosarcoma: a multicentre, single-arm, phase 2 trial. Lancet Oncol. 2019 09; 20(9):1252-1262. Stacchiotti S, Ferrari S, Redondo A, Hindi N, Palmerini E, Vaz Salgado MA, Frezza AM, Casali PG, Gutierrez A, Lopez-Pousa A, Grignani G, Italiano A, LeCesne A, Dumont S, Blay JY, Penel N, Bernabeu D, de Alava E, Karanian M, Morosi C, Brich S, Dagrada GP, Vallacchi V, Castelli C, Brenca M, Racanelli D, Maestro R, Collini P, Cruz J, Martin-Broto J. PMID: 31331701.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    42. Intraperitoneal Invasion of Retroperitoneal Sarcomas: A Risk Factor for Dismal Prognosis. Ann Surg Oncol. 2019 Oct; 26(11):3535-3541. Nizri E, Fiore M, Barretta F, Colombo C, Radaelli S, Callegaro D, Sanfilippo R, Sangalli C, Collini P, Stacchiotti S, Casali PG, Miceli R, Gronchi A. PMID: 31313035.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    43. Role of Chemotherapy, VEGFR Inhibitors, and mTOR Inhibitors in Advanced Perivascular Epithelioid Cell Tumors (PEComas). Clin Cancer Res. 2019 09 01; 25(17):5295-5300. Sanfilippo R, Jones RL, Blay JY, Le Cesne A, Provenzano S, Antoniou G, Mir O, Fucà G, Fumagalli E, Bertulli R, Stacchiotti S, Brahmi M, Grosso F, Dufresne A, Hindi N, Sbaraglia M, Gronchi A, Collini P, Dei Tos AP, Casali PG. PMID: 31217199.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    44. NR4A3 fusion proteins trigger an axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas. J Pathol. 2019 09; 249(1):90-101. Brenca M, Stacchiotti S, Fassetta K, Sbaraglia M, Janjusevic M, Racanelli D, Polano M, Rossi S, Brich S, Dagrada GP, Collini P, Colombo C, Gronchi A, Astolfi A, Indio V, Pantaleo MA, Picci P, Casali PG, Dei Tos AP, Pilotti S, Maestro R. PMID: 31020999.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    45. Management of complicated tumor response to tyrosine-kinase inhibitors in gastrointestinal stromal tumors. J Surg Oncol. 2019 Aug; 120(2):256-261. Tirotta F, Fumagalli E, Colombo C, Morosi C, Barisella M, Radaelli S, Frezza AM, Casali PG, Gronchi A, Fiore M. PMID: 31066052.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    46. Shortages of inexpensive essential medicines. Lancet Oncol. 2019 05; 20(5):e224-e225. Vyas M, de Vries EGE, Casali PG, Tabernero J. PMID: 31006527.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    47. Gain of FGF4 is a frequent event in KIT/PDGFRA/SDH/RAS-P WT GIST. Genes Chromosomes Cancer. 2019 09; 58(9):636-642. Urbini M, Indio V, Tarantino G, Ravegnini G, Angelini S, Nannini M, Saponara M, Santini D, Ceccarelli C, Fiorentino M, Vincenzi B, Fumagalli E, Casali PG, Grignani G, Pession A, Ardizzoni A, Astolfi A, Pantaleo MA. PMID: 30887595.
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    48. Trabectedin and RAdiotherapy in Soft Tissue Sarcoma (TRASTS): Results of a Phase I Study in Myxoid Liposarcoma from Spanish (GEIS), Italian (ISG), French (FSG) Sarcoma Groups. EClinicalMedicine. 2019 Mar; 9:35-43. Gronchi A, Hindi N, Cruz J, Blay JY, Lopez-Pousa A, Italiano A, Alvarez R, Gutierrez A, Rincón I, Sangalli C, Pérez Aguiar JL, Romero J, Morosi C, Sunyach MP, Sanfilippo R, Romagosa C, Ranchere-Vince D, Dei Tos AP, Casali PG, Martin-Broto J. PMID: 31143880.
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    49. The impact of chemotherapy on survival of patients with extremity and trunk wall soft tissue sarcoma: revisiting the results of the EORTC-STBSG 62931 randomised trial. Eur J Cancer. 2019 03; 109:51-60. Pasquali S, Pizzamiglio S, Touati N, Litiere S, Marreaud S, Kasper B, Gelderblom H, Stacchiotti S, Judson I, Dei Tos AP, Verderio P, Casali PG, Woll PJ, Gronchi A, EORTC – Soft Tissue and Bone Sarcoma Group . PMID: 30690293.
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    50. Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trial. Lancet Oncol. 2019 01; 20(1):134-144. Martin-Broto J, Stacchiotti S, Lopez-Pousa A, Redondo A, Bernabeu D, de Alava E, Casali PG, Italiano A, Gutierrez A, Moura DS, Peña-Chilet M, Diaz-Martin J, Biscuola M, Taron M, Collini P, Ranchere-Vince D, Garcia Del Muro X, Grignani G, Dumont S, Martinez-Trufero J, Palmerini E, Hindi N, Sebio A, Dopazo J, Dei Tos AP, LeCesne A, Blay JY, Cruz J. PMID: 30578023.
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    51. Completion surgery of residual disease after primary inadequate surgery of retroperitoneal sarcomas can salvage a selected subgroup of patients-A propensity score analysis. J Surg Oncol. 2019 Mar; 119(3):318-323. Nizri E, Fiore M, Colombo C, Radaelli S, Callegaro D, Sanfilippo R, Sangalli C, Collini P, Morosi C, Stacchiotti S, Casali PG, Gronchi A. PMID: 30554403.
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    52. Treatment Outcomes and Sensitivity to Hormone Therapy of Aggressive Angiomyxoma: A Multicenter, International, Retrospective Study. Oncologist. 2019 07; 24(7):e536-e541. Fucà G, Hindi N, Ray-Coquard I, Colia V, Dei Tos AP, Martin-Broto J, Brahmi M, Collini P, Lorusso D, Raspagliesi F, Pantaleo MA, Vincenzi B, Fumagalli E, Gronchi A, Casali PG, Sanfilippo R. PMID: 30518617.
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    53. Impact of perioperative chemotherapy and radiotherapy in patients with primary extremity soft tissue sarcoma: retrospective analysis across major histological subtypes and major reference centres. Eur J Cancer. 2018 12; 105:19-27. Callegaro D, Miceli R, Bonvalot S, Ferguson P, Strauss DC, Levy A, Griffin A, Hayes AJ, Stacchiotti S, Le Pèchoux C, Smith MJ, Fiore M, Dei Tos AP, Smith HG, Catton C, Casali PG, Wunder JS, Gronchi A. PMID: 30384013.
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    54. Best practices for the management of thymic epithelial tumors: A position paper by the Italian collaborative group for ThYmic MalignanciEs (TYME). Cancer Treat Rev. 2018 Dec; 71:76-87. Imbimbo M, Ottaviano M, Vitali M, Fabbri A, Leuzzi G, Fiore M, Franceschini D, Pasello G, Perrino M, Schiavon M, Pruneri G, Dei Tos AP, Sangalli C, Garassino MC, Berardi R, Alessi A, Calareso G, Petrini I, Scorsetti M, Scotti V, Rosso L, Rea F, Pastorino U, Casali PG, Ramella S, Ricardi U, Abate-Daga L, Torri V, Trama A, Palmieri G, Marino M, Zucali PA, TYME network collaborators . PMID: 30366202.
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    55. Imatinib and everolimus in patients with progressing advanced chordoma: A phase 2 clinical study. Cancer. 2018 10 15; 124(20):4056-4063. Stacchiotti S, Morosi C, Lo Vullo S, Casale A, Palassini E, Frezza AM, Dinoi G, Messina A, Gronchi A, Cavalleri A, Venturelli E, Morelli D, Pilotti S, Collini P, Brich S, Tamborini E, Mariani L, Casali PG. PMID: 30216418.
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    56. Survival of adults with cancers of bone or soft tissue in Europe-Report from the EUROCARE-5 study. Cancer Epidemiol. 2018 10; 56:146-153. Stiller CA, Botta L, Brewster DH, Ho VKY, Frezza AM, Whelan J, Casali PG, Trama A, Gatta G, EUROCARE-5 Working Group . PMID: 30179828.
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    57. Anthracycline, Gemcitabine, and Pazopanib in Epithelioid Sarcoma: A Multi-institutional Case Series. JAMA Oncol. 2018 09 01; 4(9):e180219. Frezza AM, Jones RL, Lo Vullo S, Asano N, Lucibello F, Ben-Ami E, Ratan R, Teterycz P, Boye K, Brahmi M, Palmerini E, Fedenko A, Vincenzi B, Brunello A, Desar IME, Benjamin RS, Blay JY, Broto JM, Casali PG, Gelderblom H, Grignani G, Gronchi A, Hall KS, Mir O, Rutkowski P, Wagner AJ, Anurova O, Collini P, Dei Tos AP, Flucke U, Hornick JL, Lobmaier I, Philippe T, Picci P, Ranchere D, Renne SL, Sbaraglia M, Thway K, Wagrodzki M, Wang WL, Yoshida A, Mariani L, Kawai A, Stacchiotti S. PMID: 29800950.
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    58. Imatinib rechallenge in patients with advanced gastrointestinal stromal tumors following progression with imatinib, sunitinib and regorafenib. Ther Adv Med Oncol. 2018; 10:1758835918794623. Vincenzi B, Nannini M, Badalamenti G, Grignani G, Fumagalli E, Gasperoni S, D'Ambrosio L, Incorvaia L, Stellato M, Spalato Ceruso M, Napolitano A, Valeri S, Santini D, Tonini G, Casali PG, Dei Tos AP, Pantaleo MA. PMID: 30181783.
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    59. A phase II randomised (calibrated design) study on the activity of the single-agent trabectedin in metastatic or locally relapsed uterine leiomyosarcoma. Br J Cancer. 2018 08; 119(5):565-571. Gadducci A, Grosso F, Scambia G, Raspagliesi F, Colombo N, Grignani G, Casali P, Sanfilippo R, Buonadonna A, Santoro A, Bruzzone M, Artioli G, Lorusso D, Biagioli E, Fossati R, Galli F, Negri E, Rulli E, Torri V, D'Incalci M. PMID: 30057406.
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    60. Prolonged activity and toxicity of sirolimus in a patient with metastatic renal perivascular epithelioid cell tumor: a case report and literature review. Anticancer Drugs. 2018 07; 29(6):589-595. Raimondi A, Colombo F, Pintarelli G, Morosi C, Renne SL, Frezza AM, Saponara M, Dei Tos AP, Mazzocchi A, Provenzano S, Casali PG, Stacchiotti S. PMID: 29668485.
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    61. 2018 ESMO Sarcoma and GIST Symposium: 'take-home messages' in soft tissue sarcoma. ESMO Open. 2018; 3(4):e000390. Frezza AM, Lee ATJ, Nizri E, Sbaraglia M, Jones RL, Gronchi A, Dei Tos AP, Casali PG. PMID: 30018812.
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    62. Identification of an Actionable Mutation of KIT in a Case of Extraskeletal Myxoid Chondrosarcoma. Int J Mol Sci. 2018 Jun 23; 19(7). Urbini M, Indio V, Astolfi A, Tarantino G, Renne SL, Pilotti S, Dei Tos AP, Maestro R, Collini P, Nannini M, Saponara M, Murrone L, Dagrada GP, Colombo C, Gronchi A, Pession A, Casali PG, Stacchiotti S, Pantaleo MA. PMID: 29937513.
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    63. Postoperative Morbidity After Radical Resection of Primary Retroperitoneal Sarcoma: A Report From the Transatlantic RPS Working Group. Ann Surg. 2018 05; 267(5):959-964. MacNeill AJ, Gronchi A, Miceli R, Bonvalot S, Swallow CJ, Hohenberger P, Van Coevorden F, Rutkowski P, Callegaro D, Hayes AJ, Honoré C, Fairweather M, Cannell A, Jakob J, Haas RL, Szacht M, Fiore M, Casali PG, Pollock RE, Barretta F, Raut CP, Strauss DC. PMID: 28394870.
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    64. Networking in rare cancers: What was done, what's next. Eur J Surg Oncol. 2019 01; 45(1):16-18. Frezza AM, Trama A, Blay JY, Casali PG. PMID: 29685758.
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    65. Denosumab treatment of inoperable or locally advanced giant cell tumor of bone - Multicenter analysis outside clinical trial. Eur J Surg Oncol. 2018 09; 44(9):1384-1390. Rutkowski P, Gaston L, Borkowska A, Stacchiotti S, Gelderblom H, Baldi GG, Palmerini E, Casali P, Gronchi A, Parry M, Campanacci DA, Scoccianti G, Wagrodzki M, Ferrari S, Dijkstra S, Pienkowski A, Grimer R. PMID: 29650420.
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    66. Nilotinib in locally advanced pigmented villonodular synovitis: a multicentre, open-label, single-arm, phase 2 trial. Lancet Oncol. 2018 05; 19(5):639-648. Gelderblom H, Cropet C, Chevreau C, Boyle R, Tattersall M, Stacchiotti S, Italiano A, Piperno-Neumann S, Le Cesne A, Ferraresi V, Penel N, Duffaud F, Cassier P, Toulmonde M, Casali P, Taieb S, Guillemaut S, Metzger S, Pérol D, Blay JY. PMID: 29571946.
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    67. Adequate Local Control in High-Risk Soft Tissue Sarcoma of the Extremity Treated with Surgery Alone at a Reference Centre: Should Radiotherapy Still be a Standard? Ann Surg Oncol. 2018 Jun; 25(6):1536-1543. Fiore M, Ford S, Callegaro D, Sangalli C, Colombo C, Radaelli S, Frezza AM, Renne SL, Casali PG, Gronchi A. PMID: 29470819.
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    68. High-risk soft tissue sarcomas treated with perioperative chemotherapy: Improving prognostic classification in a randomised clinical trial. Eur J Cancer. 2018 04; 93:28-36. Pasquali S, Colombo C, Pizzamiglio S, Verderio P, Callegaro D, Stacchiotti S, Martin Broto J, Lopez-Pousa A, Ferrari S, Poveda A, De Paoli A, Quagliuolo V, Jurado JC, Comandone A, Grignani G, De Sanctis R, Palassini E, Llomboart-Bosch A, Dei Tos AP, Casali PG, Picci P, Gronchi A. PMID: 29475197.
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    69. Global cancer control: responding to the growing burden, rising costs and inequalities in access. ESMO Open. 2018; 3(2):e000285. Prager GW, Braga S, Bystricky B, Qvortrup C, Criscitiello C, Esin E, Sonke GS, Martínez GA, Frenel JS, Karamouzis M, Strijbos M, Yazici O, Bossi P, Banerjee S, Troiani T, Eniu A, Ciardiello F, Tabernero J, Zielinski CC, Casali PG, Cardoso F, Douillard JY, Jezdic S, McGregor K, Bricalli G, Vyas M, Ilbawi A. PMID: 29464109.
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    70. Response to isolated limb perfusion and chemotherapy with epirubicin plus ifosfamide in a metastatic malignant ossifying fibromyxoid tumor. Clin Sarcoma Res. 2017; 7:20. Provenzano S, Raimondi A, Bertulli RM, Colia V, Renne SL, Collini P, Dagrada G, Callegaro D, Fiore M, Greco FG, Casali PG. PMID: 29299229.
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    71. Personalization of regorafenib treatment in metastatic gastrointestinal stromal tumours in real-life clinical practice. Ther Adv Med Oncol. 2017 Dec; 9(12):731-739. Nannini M, Nigro MC, Vincenzi B, Fumagalli E, Grignani G, D'Ambrosio L, Badalamenti G, Incorvaia L, Bracci R, Gasperoni S, Saponara M, Gatto L, Indio V, Astolfi A, Di Scioscio V, Casali PG, Tonini G, Aglietta M, Russo A, Biasco G, Pantaleo MA. PMID: 29449894.
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    72. Identification of IL-40, a Novel B Cell-Associated Cytokine. J Immunol. 2017 11 01; 199(9):3326-3335. Catalan-Dibene J, Vazquez MI, Luu VP, Nuccio SP, Karimzadeh A, Kastenschmidt JM, Villalta SA, Ushach I, Pone EJ, Casali P, Raffatellu M, Burkhardt AM, Hernandez-Ruiz M, Heller G, Hevezi PA, Zlotnik A. PMID: 28978694.
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    73. Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation. J Vis Exp. 2017 09 20; (127). Sanchez HN, Shen T, Garcia D, Lai Z, Casali P, Zan H. PMID: 28994753.
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    74. Treatment challenges in and outside a network setting: Soft tissue sarcomas. Eur J Surg Oncol. 2019 01; 45(1):31-39. Pasquali S, Bonvalot S, Tzanis D, Casali PG, Trama A, Gronchi A, RARECARENet Working Group . PMID: 28985973.
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    75. High-Dose Ifosfamide Chemotherapy in a Series of Patients Affected by Myxoid Liposarcoma. Sarcoma. 2017; 2017:3739159. Colia V, Fumagalli E, Provenzano S, Bertulli R, Stacchiotti S, Morosi C, Collini P, Gronchi A, Casali PG, Sanfilippo R. PMID: 28947876.
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    76. Activity of anthracycline- and ifosfamide-based chemotherapy in a series of patients affected by advanced myxofibrosarcoma. Clin Sarcoma Res. 2017; 7:16. Colia V, Fiore M, Provenzano S, Fumagalli E, Bertulli R, Morosi C, Dei Tos AP, Barisella M, Gronchi A, Casali PG, Sanfilippo R. PMID: 28852467.
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    77. Activity of Pazopanib and Trabectedin in Advanced Alveolar Soft Part Sarcoma. Oncologist. 2018 01; 23(1):62-70. Stacchiotti S, Mir O, Le Cesne A, Vincenzi B, Fedenko A, Maki RG, Somaiah N, Patel S, Brahmi M, Blay JY, Boye K, Sundby Hall K, Gelderblom H, Hindi N, Martin-Broto J, Kosela H, Rutkowski P, Italiano A, Duffaud F, Kobayashi E, Casali PG, Provenzano S, Kawai A. PMID: 28754721.
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    78. Identifying critical steps towards improved access to innovation in cancer care: a European CanCer Organisation position paper. Eur J Cancer. 2017 09; 82:193-202. Aapro M, Astier A, Audisio R, Banks I, Bedossa P, Brain E, Cameron D, Casali P, Chiti A, De Mattos-Arruda L, Kelly D, Lacombe D, Nilsson PJ, Piccart M, Poortmans P, Riklund K, Saeter G, Schrappe M, Soffietti R, Travado L, van Poppel H, Wait S, Naredi P. PMID: 28692951.
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    79. Neoadjuvant treatment: a novel standard? Curr Opin Oncol. 2017 Jul; 29(4):253-259. Pasquali S, Palassini E, Stacchiotti S, Casali PG, Gronchi A. PMID: 28426465.
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    80. Radiomic analysis of soft tissues sarcomas can distinguish intermediate from high-grade lesions. J Magn Reson Imaging. 2018 03; 47(3):829-840. Corino VDA, Montin E, Messina A, Casali PG, Gronchi A, Marchianò A, Mainardi LT. PMID: 28653477.
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    81. Human equilibrative nucleoside transporter 1 gene expression is associated with gemcitabine efficacy in advanced leiomyosarcoma and angiosarcoma. Br J Cancer. 2017 Jul 25; 117(3):340-346. Vincenzi B, Stacchiotti S, Collini P, Pantano F, Rabitti C, Perrone G, Iuliani M, Baldi A, Badalamenti G, Sanfilippo R, Santini D, Muda AO, Gronchi A, Casali P, Dei Tos AP, Tonini G. PMID: 28641307.
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    82. Identification of SRF-E2F1 fusion transcript in EWSR-negative myoepithelioma of the soft tissue. Oncotarget. 2017 Sep 01; 8(36):60036-60045. Urbini M, Astolfi A, Indio V, Tarantino G, Serravalle S, Saponara M, Nannini M, Gronchi A, Fiore M, Maestro R, Brenca M, Dei Tos AP, Dagrada GP, Negri T, Pilotti S, Casali PG, Biasco G, Pession A, Stacchiotti S, Pantaleo MA. PMID: 28947952.
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    83. Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trial. Lancet Oncol. 2017 06; 18(6):812-822. Gronchi A, Ferrari S, Quagliuolo V, Broto JM, Pousa AL, Grignani G, Basso U, Blay JY, Tendero O, Beveridge RD, Ferraresi V, Lugowska I, Merlo DF, Fontana V, Marchesi E, Donati DM, Palassini E, Palmerini E, De Sanctis R, Morosi C, Stacchiotti S, Bagué S, Coindre JM, Dei Tos AP, Picci P, Bruzzi P, Casali PG. PMID: 28499583.
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    84. HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma. Genes Chromosomes Cancer. 2017 07; 56(7):582-586. Urbini M, Astolfi A, Pantaleo MA, Serravalle S, Dei Tos AP, Picci P, Indio V, Sbaraglia M, Benini S, Righi A, Gambarotti M, Gronchi A, Colombo C, Dagrada GP, Pilotti S, Maestro R, Polano M, Saponara M, Tarantino G, Pession A, Biasco G, Casali PG, Stacchiotti S. PMID: 28383167.
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    85. Improving treatment results with reference centres for rare cancers: where do we stand? Eur J Cancer. 2017 05; 77:90-98. Ray-Coquard I, Pujade Lauraine E, Le Cesne A, Pautier P, Vacher Lavenue MC, Trama A, Casali P, Coindre JM, Blay JY. PMID: 28384534.
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    86. Ten-Year Progression-Free and Overall Survival in Patients With Unresectable or Metastatic GI Stromal Tumors: Long-Term Analysis of the European Organisation for Research and Treatment of Cancer, Italian Sarcoma Group, and Australasian Gastrointestinal Trials Group Intergroup Phase III Randomized Trial on Imatinib at Two Dose Levels. J Clin Oncol. 2017 May 20; 35(15):1713-1720. Casali PG, Zalcberg J, Le Cesne A, Reichardt P, Blay JY, Lindner LH, Judson IR, Schöffski P, Leyvraz S, Italiano A, Grünwald V, Pousa AL, Kotasek D, Sleijfer S, Kerst JM, Rutkowski P, Fumagalli E, Hogendoorn P, Litière S, Marreaud S, van der Graaf W, Gronchi A, Verweij J, European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group, Itali . PMID: 28362562.
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    87. Correction: Scaffold Functions of 14-3-3 Adaptors in B Cell Immunoglobulin Class Switch DNA Recombination. PLoS One. 2017; 12(3):e0174195. Lam T, Thomas LM, White CA, Li G, Pone EJ, Xu Z, Casali P. PMID: 28296964.
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    88. Long-term Efficacy of Methotrexate Plus Vinblastine/Vinorelbine in a Large Series of Patients Affected by Desmoid-Type Fibromatosis. Cancer J. 2017 Mar/Apr; 23(2):86-91. Palassini E, Frezza AM, Mariani L, Lalli L, Colombo C, Fiore M, Messina A, Casale A, Morosi C, Collini P, Stacchiotti S, Casali PG, Gronchi A. PMID: 28410293.
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    89. How a Clinical Trial Unit can improve independent clinical research in rare tumors: the Italian Sarcoma Group experience. Clin Sarcoma Res. 2017; 7:4. Marchesi E, Cagnazzo C, Quattrini I, Leopardi MP, Villa C, Grignani G, D'Ambrosio L, Stacchiotti S, Casali PG, Picci P. PMID: 28261443.
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    90. Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination. Nat Commun. 2017 02 08; 8:14244. Zan H, Tat C, Qiu Z, Taylor JR, Guerrero JA, Shen T, Casali P. PMID: 28176781.
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    91. Post-relapse outcomes after primary extended resection of retroperitoneal sarcoma: A report from the Trans-Atlantic RPS Working Group. Cancer. 2017 06 01; 123(11):1971-1978. MacNeill AJ, Miceli R, Strauss DC, Bonvalot S, Hohenberger P, Van Coevorden F, Rutkowski P, Callegaro D, Hayes AJ, Honoré C, Fairweather M, Cannell A, Jakob J, Haas RL, Szacht M, Fiore M, Casali PG, Pollock RE, Raut CP, Gronchi A, Swallow CJ. PMID: 28152173.
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    92. Genome-Wide Analysis Identifies MEN1 and MAX Mutations and a Neuroendocrine-Like Molecular Heterogeneity in Quadruple WT GIST. Mol Cancer Res. 2017 05; 15(5):553-562. Pantaleo MA, Urbini M, Indio V, Ravegnini G, Nannini M, De Luca M, Tarantino G, Angelini S, Gronchi A, Vincenzi B, Grignani G, Colombo C, Fumagalli E, Gatto L, Saponara M, Ianni M, Paterini P, Santini D, Pirini MG, Ceccarelli C, Altimari A, Gruppioni E, Renne SL, Collini P, Stacchiotti S, Brandi G, Casali PG, Pinna AD, Astolfi A, Biasco G. PMID: 28130400.
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    93. Biosimilars: a position paper of the European Society for Medical Oncology, with particular reference to oncology prescribers. ESMO Open. 2016; 1(6):e000142. Tabernero J, Vyas M, Giuliani R, Arnold D, Cardoso F, Casali PG, Cervantes A, Eggermont AMM, Eniu A, Jassem J, Pentheroudakis G, Peters S, Rauh S, Zielinski CC, Stahel RA, Voest E, Douillard JY, McGregor K, Ciardiello F. PMID: 28848668.
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    94. Advances and controversies in the management of soft tissue sarcomas. Future Oncol. 2017 Jan; 13(1s):3-11. Demetri GD, Blay JY, Casali PG. PMID: 27918199.
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    95. ECCO Essential Requirements for Quality Cancer Care: Soft Tissue Sarcoma in Adults and Bone Sarcoma. A critical review. Crit Rev Oncol Hematol. 2017 02; 110:94-105. Andritsch E, Beishon M, Bielack S, Bonvalot S, Casali P, Crul M, Delgado Bolton R, Donati DM, Douis H, Haas R, Hogendoorn P, Kozhaeva O, Lavender V, Lovey J, Negrouk A, Pereira P, Roca P, de Lempdes GR, Saarto T, van Berck B, Vassal G, Wartenberg M, Yared W, Costa A, Naredi P. PMID: 28109409.
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    96. Career opportunities and benefits for young oncologists in the European Society for Medical Oncology (ESMO). ESMO Open. 2016; 1(6):e000107. Morgan G, Lambertini M, Kourie HR, Amaral T, Argiles G, Banerjee S, Cardone C, Corral J, De Mattos-Arruda L, Öztürk A, Petrova M, Poulsen L, Strijbos M, Tyulyandina A, Vidra R, Califano R, de Azambuja E, Garrido Lopez P, Guarneri V, Reck M, Moiseyenko V, Martinelli E, Douillard JY, Stahel R, Voest E, Arnold D, Cardoso F, Casali P, Cervantes A, Eggermont AMM, Eniu A, Jassem J, Pentheroudakis G, Peters S, McGregor K, Rauh S, Zielinski CC, Ciardiello F, Tabernero J, Preusser M. PMID: 28255451.
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    97. (Neo)adjuvant treatment in localised soft tissue sarcoma: The unsolved affair. Eur J Cancer. 2017 01; 70:1-11. Saponara M, Stacchiotti S, Casali PG, Gronchi A. PMID: 27866094.
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    98. Epithelioid peritoneal mesothelioma: a hybrid phenotype within a mesenchymal-epithelial/epithelial-mesenchymal transition framework. Oncotarget. 2016 11 15; 7(46):75503-75517. Bozzi F, Brich S, Dagrada GP, Negri T, Conca E, Cortelazzi B, Belfiore A, Perrone F, Gualeni AV, Gloghini A, Cabras A, Brenca M, Maestro R, Zaffaroni N, Casali P, Bertulli R, Deraco M, Pilotti S. PMID: 27705913.
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    99. Morcellation worsens survival outcomes in patients with undiagnosed uterine leiomyosarcomas: A retrospective MITO group study. Gynecol Oncol. 2017 Jan; 144(1):90-95. Raspagliesi F, Maltese G, Bogani G, Fucà G, Lepori S, De Iaco P, Perrone M, Scambia G, Cormio G, Bogliolo S, Bergamini A, Bifulco G, Casali PG, Lorusso D. PMID: 27817933.
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    100. Imatinib dose escalation versus sunitinib as a second line treatment in KIT exon 11 mutated GIST: a retrospective analysis. Oncotarget. 2016 10 25; 7(43):69412-69419. Vincenzi B, Nannini M, Fumagalli E, Bronte G, Frezza AM, De Lisi D, Spalato Ceruso M, Santini D, Badalamenti G, Pantaleo MA, Russo A, Dei Tos AP, Casali P, Tonini G. PMID: 26416414.
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    101. Small Molecule Inhibition of Rab7 Impairs B Cell Class Switching and Plasma Cell Survival To Dampen the Autoantibody Response in Murine Lupus. J Immunol. 2016 11 15; 197(10):3792-3805. Lam T, Kulp DV, Wang R, Lou Z, Taylor J, Rivera CE, Yan H, Zhang Q, Wang Z, Zan H, Ivanov DN, Zhong G, Casali P, Xu Z. PMID: 27742832.
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    102. ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016. ESMO Open. 2016; 1(5):e000097. Dittrich C, Kosty M, Jezdic S, Pyle D, Berardi R, Bergh J, El-Saghir N, Lotz JP, Österlund P, Pavlidis N, Purkalne G, Awada A, Banerjee S, Bhatia S, Bogaerts J, Buckner J, Cardoso F, Casali P, Chu E, Close JL, Coiffier B, Connolly R, Coupland S, De Petris L, De Santis M, de Vries EG, Dizon DS, Duff J, Duska LR, Eniu A, Ernstoff M, Felip E, Fey MF, Gilbert J, Girard N, Glaudemans AW, Gopalan PK, Grothey A, Hahn SM, Hanna D, Herold C, Herrstedt J, Homicsko K, Jones DV, Jost L, Keilholz U, Khan S, Kiss A, Köhne CH, Kunstfeld R, Lenz HJ, Lichtman S, Licitra L, Lion T, Litière S, Liu L, Loehrer PJ, Markham MJ, Markman B, Mayerhoefer M, Meran JG, Michielin O, Moser EC, Mountzios G, Moynihan T, Nielsen T, Ohe Y, Öberg K, Palumbo A, Peccatori FA, Pfeilstöcker M, Raut C, Remick SC, Robson M, Rutkowski P, Salgado R, Schapira L, Schernhammer E, Schlumberger M, Schmoll HJ, Schnipper L, Sessa C, Shapiro CL, Steele J, Sternberg CN, Stiefel F, Strasser F, Stupp R, Sullivan R, Tabernero J, Travado L, Verheij M, Voest E, Vokes E, Von Roenn J, Weber JS, Wildiers H, Yarden Y. PMID: 27843641.
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    103. Current status and unanswered questions on the use of Denosumab in giant cell tumor of bone. Clin Sarcoma Res. 2016; 6(1):15. Gaston CL, Grimer RJ, Parry M, Stacchiotti S, Dei Tos AP, Gelderblom H, Ferrari S, Baldi GG, Jones RL, Chawla S, Casali P, LeCesne A, Blay JY, Dijkstra SP, Thomas DM, Rutkowski P. PMID: 27651889.
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    104. Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment. J Invest Dermatol. 2017 02; 137(2):484-493. Tazzari M, Indio V, Vergani B, De Cecco L, Rini F, Negri T, Camisaschi C, Fiore M, Stacchiotti S, Dagrada GP, Casali PG, Gronchi A, Astolfi A, Pantaleo MA, Villa A, Lombardo C, Arienti F, Pilotti S, Rivoltini L, Castelli C. PMID: 27608549.
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    105. Solitary fibrous tumour presenting with a single bone metastasis: report of six cases and literature review. Clin Sarcoma Res. 2016; 6(1):16. Colia V, Provenzano S, Morosi C, Collini P, Renne SL, Dagrada PG, Sangalli C, Dei Tos AP, Marrari A, Casali PG, Stacchiotti S. PMID: 27588167.
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    106. Sirolimus in Advanced Epithelioid Hemangioendothelioma: A Retrospective Case-Series Analysis from the Italian Rare Cancer Network Database. Ann Surg Oncol. 2016 09; 23(9):2735-44. Stacchiotti S, Provenzano S, Dagrada G, Negri T, Brich S, Basso U, Brunello A, Grosso F, Galli L, Palassini E, Libertini M, Colia V, Gronchi A, Dei Tos AP, Crippa F, Morosi C, Pilotti S, Casali PG. PMID: 27334221.
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    107. Evolution of Dermatofibrosarcoma Protuberans to DFSP-Derived Fibrosarcoma: An Event Marked by Epithelial-Mesenchymal Transition-like Process and 22q Loss. Mol Cancer Res. 2016 09; 14(9):820-9. Stacchiotti S, Astolfi A, Gronchi A, Fontana A, Pantaleo MA, Negri T, Brenca M, Tazzari M, Urbini M, Indio V, Colombo C, Radaelli S, Brich S, Dei Tos AP, Casali PG, Castelli C, Dagrada GP, Pilotti S, Maestro R. PMID: 27256159.
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    108. Sacral Chordoma: Long-term Outcome of a Large Series of Patients Surgically Treated at Two Reference Centers. Spine (Phila Pa 1976). 2016 Jun; 41(12):1049-1057. Radaelli S, Stacchiotti S, Ruggieri P, Donati D, Casali PG, Palmerini E, Collini P, Gambarotti M, Porcu L, Boriani S, Gronchi A, Picci P. PMID: 27054448.
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    109. Vascular resection en-bloc with tumor removal and graft reconstruction is safe and effective in soft tissue sarcoma (STS) of the extremities and retroperitoneum. Surg Oncol. 2016 Sep; 25(3):125-31. Radaelli S, Fiore M, Colombo C, Ford S, Palassini E, Sanfilippo R, Stacchiotti S, Sangalli C, Morosi C, Casali PG, Gronchi A. PMID: 27566012.
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    110. Variability in Patterns of Recurrence After Resection of Primary Retroperitoneal Sarcoma (RPS): A Report on 1007 Patients From the Multi-institutional Collaborative RPS Working Group. Ann Surg. 2016 May; 263(5):1002-9. Gronchi A, Strauss DC, Miceli R, Bonvalot S, Swallow CJ, Hohenberger P, Van Coevorden F, Rutkowski P, Callegaro D, Hayes AJ, Honoré C, Fairweather M, Cannell A, Jakob J, Haas RL, Szacht M, Fiore M, Casali PG, Pollock RE, Raut CP. PMID: 26727100.
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    111. Development and external validation of two nomograms to predict overall survival and occurrence of distant metastases in adults after surgical resection of localised soft-tissue sarcomas of the extremities: a retrospective analysis. Lancet Oncol. 2016 05; 17(5):671-80. Callegaro D, Miceli R, Bonvalot S, Ferguson P, Strauss DC, Levy A, Griffin A, Hayes AJ, Stacchiotti S, Pechoux CL, Smith MJ, Fiore M, Dei Tos AP, Smith HG, Mariani L, Wunder JS, Pollock RE, Casali PG, Gronchi A. PMID: 27068860.
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    112. External validation of a multi-institutional retroperitoneal sarcoma nomogram. Cancer. 2016 May 01; 122(9):1417-24. Raut CP, Miceli R, Strauss DC, Swallow CJ, Hohenberger P, van Coevorden F, Rutkowski P, Fiore M, Callegaro D, Casali PG, Haas RL, Hayes AJ, Honore C, Cannell AJ, Jakob J, Szacht M, Fairweather M, Pollock RE, Bonvalot S, Gronchi A. PMID: 26916507.
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    113. Systemic therapy for selected skull base sarcomas: Chondrosarcoma, chordoma, giant cell tumour and solitary fibrous tumour/hemangiopericytoma. Rep Pract Oncol Radiother. 2016 Jul-Aug; 21(4):361-9. Colia V, Provenzano S, Hindi N, Casali PG, Stacchiotti S. PMID: 27330421.
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    114. Editorial: Epigenetics of B Cells and Antibody Responses. Front Immunol. 2015; 6:656. Zan H, Casali P. PMID: 26793194.
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    115. Genome-Wide Analysis Reveals Selective Modulation of microRNAs and mRNAs by Histone Deacetylase Inhibitor in B Cells Induced to Undergo Class-Switch DNA Recombination and Plasma Cell Differentiation. Front Immunol. 2015; 6:627. Shen T, Sanchez HN, Zan H, Casali P. PMID: 26697020.
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    116. Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response. Front Immunol. 2015; 6:631. Zan H, Casali P. PMID: 26697022.
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    117. Adjuvant Imatinib for GI Stromal Tumors: When and For How Long? J Clin Oncol. 2016 Jan 20; 34(3):215-8. Benjamin RS, Casali PG. PMID: 26644523.
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    118. Hormonal manipulation with toremifene in sporadic desmoid-type fibromatosis. Eur J Cancer. 2015 Dec; 51(18):2800-7. Fiore M, Colombo C, Radaelli S, Callegaro D, Palassini E, Barisella M, Morosi C, Baldi GG, Stacchiotti S, Casali PG, Gronchi A. PMID: 26602014.
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    119. Time to Definitive Failure to the First Tyrosine Kinase Inhibitor in Localized GI Stromal Tumors Treated With Imatinib As an Adjuvant: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Intergroup Randomized Trial in Collaboration With the Australasian Gastro-Intestinal Trials Group, UNICANCER, French Sarcoma Group, Italian Sarcoma Group, and Spanish Group for Research on Sarcomas. J Clin Oncol. 2015 Dec 20; 33(36):4276-83. Casali PG, Le Cesne A, Poveda Velasco A, Kotasek D, Rutkowski P, Hohenberger P, Fumagalli E, Judson IR, Italiano A, Gelderblom H, Adenis A, Hartmann JT, Duffaud F, Goldstein D, Broto JM, Gronchi A, Dei Tos AP, Marréaud S, van der Graaf WT, Zalcberg JR, Litière S, Blay JY. PMID: 26573069.
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    120. Regulation of B Cell Differentiation by Intracellular Membrane-Associated Proteins and microRNAs: Role in the Antibody Response. Front Immunol. 2015; 6:537. Lou Z, Casali P, Xu Z. PMID: 26579118.
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    121. Feasibility of Preoperative Chemotherapy With or Without Radiation Therapy in Localized Soft Tissue Sarcomas of Limbs and Superficial Trunk in the Italian Sarcoma Group/Grupo Español de Investigación en Sarcomas Randomized Clinical Trial: Three Versus Five Cycles of Full-Dose Epirubicin Plus Ifosfamide. J Clin Oncol. 2015 Nov 01; 33(31):3628-34. Palassini E, Ferrari S, Verderio P, De Paoli A, Martin Broto J, Quagliuolo V, Comandone A, Sangalli C, Palmerini E, Lopez-Pousa A, De Sanctis R, Bottelli S, Libertini M, Picci P, Casali PG, Gronchi A. PMID: 26351345.
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    122. Imatinib in advanced chordoma: A retrospective case series analysis. Eur J Cancer. 2015 Nov; 51(17):2609-14. Hindi N, Casali PG, Morosi C, Messina A, Palassini E, Pilotti S, Tamborini E, Radaelli S, Gronchi A, Stacchiotti S. PMID: 26283036.
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    123. Efficacy and Biological Activity of Imatinib in Metastatic Dermatofibrosarcoma Protuberans (DFSP). Clin Cancer Res. 2016 Feb 15; 22(4):837-46. Stacchiotti S, Pantaleo MA, Negri T, Astolfi A, Tazzari M, Dagrada GP, Urbini M, Indio V, Maestro R, Gronchi A, Fiore M, Dei Tos AP, Conca E, Palassini E, Vincenzi B, Grosso F, Pilotti S, Castelli C, Casali PG. PMID: 26261104.
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    124. The GOLD ReGISTry: a Global, Prospective, Observational Registry Collecting Longitudinal Data on Patients with Advanced and Localised Gastrointestinal Stromal Tumours. Eur J Cancer. 2015 Nov; 51(16):2423-33. Barrios CH, Blackstein ME, Blay JY, Casali PG, Chacon M, Gu J, Kang YK, Nishida T, Purkayastha D, Woodman RC, Reichardt P. PMID: 26248685.
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    125. Trabectedin in advanced synovial sarcomas: a multicenter retrospective study from four European institutions and the Italian Rare Cancer Network. Anticancer Drugs. 2015 Jul; 26(6):678-81. Sanfilippo R, Dileo P, Blay JY, Constantinidou A, Le Cesne A, Benson C, Vizzini L, Contu M, Baldi GG, Dei Tos AP, Casali PG. PMID: 25763543.
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    126. KIT, PDGFRA, and BRAF mutational spectrum impacts on the natural history of imatinib-naive localized GIST: a population-based study. Am J Surg Pathol. 2015 Jul; 39(7):922-30. Rossi S, Gasparotto D, Miceli R, Toffolatti L, Gallina G, Scaramel E, Marzotto A, Boscato E, Messerini L, Bearzi I, Mazzoleni G, Capella C, Arrigoni G, Sonzogni A, Sidoni A, Mariani L, Amore P, Gronchi A, Casali PG, Maestro R, Dei Tos AP. PMID: 25970686.
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    127. Hope in cancer patients: the relational domain as a crucial factor. Tumori. 2015 Jul-Aug; 101(4):447-54. Proserpio T, Ferrari A, Lo Vullo S, Massimino M, Clerici CA, Veneroni L, Bresciani C, Casali PG, Ferrari M, Bossi P, Galmozzi G, Pierantozzi A, Licitra L, Marceglia S, Mariani L. PMID: 26045106.
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    128. Development and validation of prognostic nomograms for metastatic gastrointestinal stromal tumour treated with imatinib. Eur J Cancer. 2015 May; 51(7):852-60. Lee CK, Goldstein D, Gibbs E, Joensuu H, Zalcberg J, Verweij J, Casali PG, Maki RG, Cioffi A, Mcarthur G, Lord SJ, Yip D, Kanjanapan Y, Rutkowski P. PMID: 25801699.
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    129. Response of conventional chondrosarcoma to gemcitabine alone: a case report. Clin Sarcoma Res. 2015; 5:9. Provenzano S, Hindi N, Morosi C, Ghilardi M, Collini P, Casali PG, Stacchiotti S. PMID: 25793102.
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    130. B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. J Immunol. 2015 Apr 01; 194(7):3065-78. Pone EJ, Lam T, Lou Z, Wang R, Chen Y, Liu D, Edinger AL, Xu Z, Casali P. PMID: 25740947.
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    131. Myogenic differentiation and histologic grading are major prognostic determinants in retroperitoneal liposarcoma. Am J Surg Pathol. 2015 Mar; 39(3):383-93. Gronchi A, Collini P, Miceli R, Valeri B, Renne SL, Dagrada G, Fiore M, Sanfilippo R, Barisella M, Colombo C, Morosi C, Stacchiotti S, Casali PG, Dei Tos AP, Pilotti S. PMID: 25581729.
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    132. Management of Gastrointestinal Stromal Tumour: Current Practices and Visions for the Future. Oncology. 2015; 89(1):1-13. Blay JY, Casali PG, Dei Tos AP, Le Cesne A, Reichardt P. PMID: 25720422.
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    133. Melan-A/MART-1 immunity in a EWS-ATF1 translocated clear cell sarcoma patient treated with sunitinib: a case report. BMC Cancer. 2015 Feb 14; 15:58. Tazzari M, Palassini E, Vergani B, Villa A, Rini F, Negri T, Colombo C, Crippa F, Morosi C, Casali PG, Pilotti S, Stacchiotti S, Rivoltini L, Castelli C. PMID: 25880253.
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    134. B cell TLR1/2, TLR4, TLR7 and TLR9 interact in induction of class switch DNA recombination: modulation by BCR and CD40, and relevance to T-independent antibody responses. Autoimmunity. 2015 Feb; 48(1):1-12. Pone EJ, Lou Z, Lam T, Greenberg ML, Wang R, Xu Z, Casali P. PMID: 25536171.
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    135. Understanding Deviations from Clinical Practice Guidelines in Adult Soft Tissue Sarcoma. Stud Health Technol Inform. 2015; 216:280-4. Goldbraich E, Waks Z, Farkash A, Monti M, Torresani M, Bertulli R, Casali PG, Carmeli B. PMID: 26262055.
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    136. Adjuvant chemotherapy for soft tissue sarcoma. Am Soc Clin Oncol Educ Book. 2015; e629-33. Casali PG. PMID: 25993233.
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    137. Sorafenib and everolimus for patients with unresectable high-grade osteosarcoma progressing after standard treatment: a non-randomised phase 2 clinical trial. Lancet Oncol. 2015 Jan; 16(1):98-107. Grignani G, Palmerini E, Ferraresi V, D'Ambrosio L, Bertulli R, Asaftei SD, Tamburini A, Pignochino Y, Sangiolo D, Marchesi E, Capozzi F, Biagini R, Gambarotti M, Fagioli F, Casali PG, Picci P, Ferrari S, Aglietta M, Italian Sarcoma Group . PMID: 25498219.
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    138. Tenosynovial giant cell tumour/pigmented villonodular synovitis: outcome of 294 patients before the era of kinase inhibitors. Eur J Cancer. 2015 Jan; 51(2):210-7. Palmerini E, Staals EL, Maki RG, Pengo S, Cioffi A, Gambarotti M, Picci P, Daolio PA, Parafioriti A, Morris C, Antonescu CR, Gronchi A, Casali PG, Donati DM, Ferrari S, Stacchiotti S. PMID: 25465190.
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    139. High-dose continuous-infusion ifosfamide in advanced well-differentiated/dedifferentiated liposarcoma. Clin Sarcoma Res. 2014; 4(1):16. Sanfilippo R, Bertulli R, Marrari A, Fumagalli E, Pilotti S, Morosi C, Messina A, Dei Tos AP, Gronchi A, Casali PG. PMID: 25628856.
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    140. Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses. J Immunol. 2014 Dec 15; 193(12):5933-50. White CA, Pone EJ, Lam T, Tat C, Hayama KL, Li G, Zan H, Casali P. PMID: 25392531.
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    141. Personalizing the approach to retroperitoneal soft tissue sarcoma: histology-specific patterns of failure and postrelapse outcome after primary extended resection. Ann Surg Oncol. 2015 May; 22(5):1447-54. Gronchi A, Miceli R, Allard MA, Callegaro D, Le Péchoux C, Fiore M, Honoré C, Sanfilippo R, Coppola S, Stacchiotti S, Terrier P, Casali PG, Le Cesne A, Mariani L, Colombo C, Bonvalot S. PMID: 25300609.
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    142. Folate-related polymorphisms in gastrointestinal stromal tumours: susceptibility and correlation with tumour characteristics and clinical outcome. Eur J Hum Genet. 2015 Jun; 23(6):817-23. Angelini S, Ravegnini G, Nannini M, Bermejo JL, Musti M, Pantaleo MA, Fumagalli E, Venturoli N, Palassini E, Consolini N, Casali PG, Biasco G, Hrelia P. PMID: 25227144.
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    143. Identification of a gene expression driven progression pathway in myxoid liposarcoma. Oncotarget. 2014 Aug 15; 5(15):5965-77. De Cecco L, Negri T, Brich S, Mauro V, Bozzi F, Dagrada G, Disciglio V, Sanfilippo R, Gronchi A, D'Incalci M, Casali PG, Canevari S, Pierotti MA, Pilotti S. PMID: 25115389.
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    144. Type II Toxoplasma gondii induction of CD40 on infected macrophages enhances interleukin-12 responses. Infect Immun. 2014 Oct; 82(10):4047-55. Morgado P, Sudarshana DM, Gov L, Harker KS, Lam T, Casali P, Boyle JP, Lodoen MB. PMID: 25024369.
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    145. MicroRNAs in lupus. Autoimmunity. 2014 Jun; 47(4):272-85. Zan H, Tat C, Casali P. PMID: 24826805.
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    146. Desmoid-type fibromatosis and pregnancy: a multi-institutional analysis of recurrence and obstetric risk. Ann Surg. 2014 May; 259(5):973-8. Fiore M, Coppola S, Cannell AJ, Colombo C, Bertagnolli MM, George S, Le Cesne A, Gladdy RA, Casali PG, Swallow CJ, Gronchi A, Bonvalot S, Raut CP. PMID: 24477160.
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    147. Ewing sarcoma of the small bowel: a study of seven cases, including one with the uncommonly reported EWSR1-FEV translocation. Histopathology. 2014 Jun; 64(7):1014-26. Milione M, Gasparini P, Sozzi G, Mazzaferro V, Ferrari A, Casali PG, Perrone F, Tamborini E, Pellegrinelli A, Gherardi G, Arrigoni G, Collini P, Testi A, De Paoli E, Aiello A, Pilotti S, Pelosi G. PMID: 24898918.
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    148. Emerging therapies for adult soft tissue sarcoma. Expert Rev Anticancer Ther. 2014 Jun; 14(6):689-704. Radaelli S, Stacchiotti S, Casali PG, Gronchi A. PMID: 24555529.
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    149. Successes and limitations of targeted cancer therapy in gastrointestinal stromal tumors. Prog Tumor Res. 2014; 41:51-61. Casali PG. PMID: 24727986.
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    150. Anthracycline-based chemotherapy in extraskeletal myxoid chondrosarcoma: a retrospective study. Clin Sarcoma Res. 2013 Dec 18; 3(1):16. Stacchiotti S, Dagrada GP, Sanfilippo R, Negri T, Vittimberga I, Ferrari S, Grosso F, Apice G, Tricomi M, Colombo C, Gronchi A, Dei Tos AP, Pilotti S, Casali PG. PMID: 24345066.
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    151. Policy statement on multidisciplinary cancer care. Eur J Cancer. 2014 Feb; 50(3):475-80. European Partnership Action Against Cancer consensus group , Borras JM, Albreht T, Audisio R, Briers E, Casali P, Esperou H, Grube B, Hamoir M, Henning G, Kelly J, Knox S, Nabal M, Pierotti M, Lombardo C, van Harten W, Poston G, Prades J, Sant M, Travado L, Valentini V, van de Velde C, van den Bogaert S, van den Bulcke M, van Hoof E, van den Neucker I, Wilson R. PMID: 24321260.
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    152. Preoperative chemo-radiation therapy for localised retroperitoneal sarcoma: a phase I-II study from the Italian Sarcoma Group. Eur J Cancer. 2014 Mar; 50(4):784-92. Gronchi A, De Paoli A, Dani C, Merlo DF, Quagliuolo V, Grignani G, Bertola G, Navarria P, Sangalli C, Buonadonna A, De Sanctis R, Sanfilippo R, Dei Tos AP, Stacchiotti S, Giorello L, Fiore M, Bruzzi P, Casali PG. PMID: 24316063.
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    153. Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination. PLoS One. 2013; 8(11):e80414. Lam T, Thomas LM, White CA, Li G, Pone EJ, Xu Z, Casali P. PMID: 24282540.
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    154. Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination. Cell Rep. 2013 Nov 14; 5(3):702-714. Li G, White CA, Lam T, Pone EJ, Tran DC, Hayama KL, Zan H, Xu Z, Casali P. PMID: 24209747.
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    155. MRP1 overexpression determines poor prognosis in prospectively treated patients with localized high-risk soft tissue sarcoma of limbs and trunk wall: an ISG/GEIS study. . 2014 Jan; 13(1):249-59. Martin-Broto J, Gutierrez AM, Ramos RF, Lopez-Guerrero JA, Ferrari S, Stacchiotti S, Picci P, Calabuig S, Collini P, Gambarotti M, Bague S, Dei Tos AP, Palassini E, Luna P, Cruz J, Cubedo R, Martinez-Trufero J, Poveda A, Casali PG, Fernandez-Serra A, Lopez-Pousa A, Gronchi A. PMID: 24145283.
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    156. Targeted therapies in rare sarcomas: IMT, ASPS, SFT, PEComa, and CCS. Hematol Oncol Clin North Am. 2013 Oct; 27(5):1049-61. Stacchiotti S, Marrari A, Dei Tos AP, Casali PG. PMID: 24093175.
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    157. Adjuvant therapy for high-risk soft tissue sarcoma in the adult. Curr Treat Options Oncol. 2013 Sep; 14(3):415-24. Gronchi A, Casali PG. PMID: 23775297.
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    158. Efficacy and safety of trabectedin as an early treatment for advanced or metastatic liposarcoma and leiomyosarcoma. Future Oncol. 2014 Jan; 10(1):59-68. Blay JY, Casali P, Nieto A, Tanovic A, Le Cesne A. PMID: 23987833.
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    159. TSPAN33 is a novel marker of activated and malignant B cells. Clin Immunol. 2013 Dec; 149(3):388-99. Luu VP, Hevezi P, Vences-Catalan F, Maravillas-Montero JL, White CA, Casali P, Llorente L, Jakez-Ocampo J, Lima G, Vilches-Cisneros N, Flores-Gutiérrez JP, Santos-Argumedo L, Zlotnik A. PMID: 24211713.
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    160. Induction of activation-induced cytidine deaminase-targeting adaptor 14-3-3? is mediated by NF-?B-dependent recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3? promoter and is sustained by E2A. J Immunol. 2013 Aug 15; 191(4):1895-906. Mai T, Pone EJ, Li G, Lam TS, Moehlman J, Xu Z, Casali P. PMID: 23851690.
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    161. Myxoid liposarcoma and the mammalian target of rapamycin pathway. Curr Opin Oncol. 2013 Jul; 25(4):379-83. Sanfilippo R, Dei Tos AP, Casali PG. PMID: 23673410.
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    162. Neoadjuvant imatinib in locally advanced gastrointestinal stromal tumors (GIST): the EORTC STBSG experience. Ann Surg Oncol. 2013 Sep; 20(9):2937-43. Rutkowski P, Gronchi A, Hohenberger P, Bonvalot S, Schöffski P, Bauer S, Fumagalli E, Nyckowski P, Nguyen BP, Kerst JM, Fiore M, Bylina E, Hoiczyk M, Cats A, Casali PG, Le Cesne A, Treckmann J, Stoeckle E, de Wilt JH, Sleijfer S, Tielen R, van der Graaf W, Verhoef C, van Coevorden F. PMID: 23760587.
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    163. The intriguing patterns of tumor response to trabectedin. Expert Rev Anticancer Ther. 2013 Jun; 13(6 Suppl 1):21-4. Sanfilippo R, Casali PG. PMID: 23638727.
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    164. Localised thoracic sarcomas: outcome improvement over time at a single institution. Eur J Cancer. 2013 Aug; 49(12):2689-97. Duranti L, Gronchi A, Stacchiotti S, Fiore M, Casali PG, Collini P, Pelosi G, Galeone C, Pastorino U. PMID: 23683891.
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    165. Response to imatinib in villonodular pigmented synovitis (PVNS) resistant to nilotinib. Clin Sarcoma Res. 2013 May 13; 3(1):8. Stacchiotti S, Crippa F, Messina A, Pilotti S, Gronchi A, Blay JY, Casali PG. PMID: 23668619.
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    166. Epigenetics of the antibody response. Trends Immunol. 2013 Sep; 34(9):460-70. Li G, Zan H, Xu Z, Casali P. PMID: 23643790.
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    167. Solitary fibrous tumor of all sites: outcome of late recurrences in 14 patients. Clin Sarcoma Res. 2013; 3:4. Baldi GG, Stacchiotti S, Mauro V, Dei Tos AP, Gronchi A, Pastorino U, Duranti L, Provenzano S, Marrari A, Libertini M, Pilotti S, Casali PG. PMID: 23551825.
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    168. Improving methodology to go beyond histology in rare cancers. Lancet Oncol. 2013 Apr; 14(4):276-7. Casali PG. PMID: 23477834.
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    169. Role of macrophage targeting in the antitumor activity of trabectedin. Cancer Cell. 2013 Feb 11; 23(2):249-62. Germano G, Frapolli R, Belgiovine C, Anselmo A, Pesce S, Liguori M, Erba E, Uboldi S, Zucchetti M, Pasqualini F, Nebuloni M, van Rooijen N, Mortarini R, Beltrame L, Marchini S, Fuso Nerini I, Sanfilippo R, Casali PG, Pilotti S, Galmarini CM, Anichini A, Mantovani A, D'Incalci M, Allavena P. PMID: 23410977.
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    170. Regulation of Aicda expression and AID activity. Autoimmunity. 2013 Mar; 46(2):83-101. Zan H, Casali P. PMID: 23181381.
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    171. Analyzing the "CareGap": assessing gaps in adherence to clinical guidelines in adult soft tissue sarcoma. Stud Health Technol Inform. 2013; 186:46-50. Waks Z, Goldbraich E, Farkash A, Torresani M, Bertulli R, Restifo N, Locatelli P, Casali P, Carmeli B. PMID: 23542965.
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    172. Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet. 2013 Jan 26; 381(9863):295-302. Demetri GD, Reichardt P, Kang YK, Blay JY, Rutkowski P, Gelderblom H, Hohenberger P, Leahy M, von Mehren M, Joensuu H, Badalamenti G, Blackstein M, Le Cesne A, Schöffski P, Maki RG, Bauer S, Nguyen BB, Xu J, Nishida T, Chung J, Kappeler C, Kuss I, Laurent D, Casali PG, GRID study investigators . PMID: 23177515.
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    173. Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombination. Cell Rep. 2012 Nov 29; 2(5):1220-32. Zan H, White CA, Thomas LM, Mai T, Li G, Xu Z, Zhang J, Casali P. PMID: 23140944.
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    174. Polymorphisms in OCTN1 and OCTN2 transporters genes are associated with prolonged time to progression in unresectable gastrointestinal stromal tumours treated with imatinib therapy. Pharmacol Res. 2013 Feb; 68(1):1-6. Angelini S, Pantaleo MA, Ravegnini G, Zenesini C, Cavrini G, Nannini M, Fumagalli E, Palassini E, Saponara M, Di Battista M, Casali PG, Hrelia P, Cantelli-Forti G, Biasco G. PMID: 23127916.
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    175. Extraskeletal myxoid chondrosarcoma: tumor response to sunitinib. Clin Sarcoma Res. 2012 Oct 11; 2(1):22. Stacchiotti S, Dagrada GP, Morosi C, Negri T, Romanini A, Pilotti S, Gronchi A, Casali PG. PMID: 23058004.
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    176. Adjuvant therapy of gastrointestinal stromal tumors (GIST). Curr Treat Options Oncol. 2012 Sep; 13(3):277-84. Casali PG, Fumagalli E, Gronchi A. PMID: 22743760.
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    177. A retrospective analysis of antitumour activity with trabectedin in translocation-related sarcomas. Eur J Cancer. 2012 Nov; 48(16):3036-44. Le Cesne A, Cresta S, Maki RG, Blay JY, Verweij J, Poveda A, Casali PG, Balaña C, Schöffski P, Grosso F, Lardelli P, Nieto A, Alfaro V, Demetri GD. PMID: 22749255.
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    178. Immunoglobulin class-switch DNA recombination: induction, targeting and beyond. Nat Rev Immunol. 2012 Jun 25; 12(7):517-31. Xu Z, Zan H, Pone EJ, Mai T, Casali P. PMID: 22728528.
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    179. Outcome of patients with platelet-derived growth factor receptor alpha-mutated gastrointestinal stromal tumors in the tyrosine kinase inhibitor era. Clin Cancer Res. 2012 Aug 15; 18(16):4458-64. Cassier PA, Fumagalli E, Rutkowski P, Schöffski P, Van Glabbeke M, Debiec-Rychter M, Emile JF, Duffaud F, Martin-Broto J, Landi B, Adenis A, Bertucci F, Bompas E, Bouché O, Leyvraz S, Judson I, Verweij J, Casali P, Blay JY, Hohenberger P, European Organisation for Research and Treatment of Cancer . PMID: 22718859.
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    180. Complete longitudinal analyses of the randomized, placebo-controlled, phase III trial of sunitinib in patients with gastrointestinal stromal tumor following imatinib failure. Clin Cancer Res. 2012 Jun 01; 18(11):3170-9. Demetri GD, Garrett CR, Schöffski P, Shah MH, Verweij J, Leyvraz S, Hurwitz HI, Pousa AL, Le Cesne A, Goldstein D, Paz-Ares L, Blay JY, McArthur GA, Xu QC, Huang X, Harmon CS, Tassell V, Cohen DP, Casali PG. PMID: 22661587.
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    181. B cell TLRs and induction of immunoglobulin class-switch DNA recombination. Front Biosci (Landmark Ed). 2012 Jun 01; 17:2594-615. Pone EJ, Xu Z, White CA, Zan H, Casali P. PMID: 22652800.
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    182. Tumor response assessment by modified Choi criteria in localized high-risk soft tissue sarcoma treated with chemotherapy. Cancer. 2012 Dec 01; 118(23):5857-66. Stacchiotti S, Verderio P, Messina A, Morosi C, Collini P, Llombart-Bosch A, Martin J, Comandone A, Cruz J, Ferraro A, Grignani G, Pizzamiglio S, Quagliuolo V, Picci P, Frustaci S, Dei Tos AP, Casali PG, Gronchi A. PMID: 22605504.
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    183. Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet. 2012 May 19; 379(9829):1879-86. van der Graaf WT, Blay JY, Chawla SP, Kim DW, Bui-Nguyen B, Casali PG, Schöffski P, Aglietta M, Staddon AP, Beppu Y, Le Cesne A, Gelderblom H, Judson IR, Araki N, Ouali M, Marreaud S, Hodge R, Dewji MR, Coens C, Demetri GD, Fletcher CD, Dei Tos AP, Hohenberger P, EORTC Soft Tissue and Bone Sarcoma Group , PALETTE study group . PMID: 22595799.
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    184. Iron inhibits activation-induced cytidine deaminase enzymatic activity and modulates immunoglobulin class switch DNA recombination. J Biol Chem. 2012 Jun 15; 287(25):21520-9. Li G, Pone EJ, Tran DC, Patel PJ, Dao L, Xu Z, Casali P. PMID: 22556412.
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    185. Leiomyosarcoma and sarcoma with myogenic differentiation: two different entities or 2 faces of the same disease? Cancer. 2012 Nov 01; 118(21):5349-57. Colombo C, Miceli R, Collini P, Radaelli S, Palassini E, Stacchiotti S, Fiore M, Mariani L, Casali PG, Gronchi A. PMID: 22517186.
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    186. BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-?B pathway. Nat Commun. 2012 Apr 03; 3:767. Pone EJ, Zhang J, Mai T, White CA, Li G, Sakakura JK, Patel PJ, Al-Qahtani A, Zan H, Xu Z, Casali P. PMID: 22473011.
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    187. PML expression in soft tissue sarcoma: prognostic and predictive value in alkylating agents/antracycline-based first line therapy. J Cell Physiol. 2012 Apr; 227(4):1657-62. Vincenzi B, Santini D, Schiavon G, Frezza AM, Silletta M, Crucitti P, Casali P, Dei Tos AP, Rossi S, Rizzo S, Badalamenti G, Tomasino RM, Russo A, Butrynski JE, Tonini G. PMID: 21678421.
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    188. Phase II study of imatinib in advanced chordoma. J Clin Oncol. 2012 Mar 20; 30(9):914-20. Stacchiotti S, Longhi A, Ferraresi V, Grignani G, Comandone A, Stupp R, Bertuzzi A, Tamborini E, Pilotti S, Messina A, Spreafico C, Gronchi A, Amore P, Vinaccia V, Casali PG. PMID: 22331945.
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    189. Short, full-dose adjuvant chemotherapy in high-risk adult soft tissue sarcomas: a randomized clinical trial from the Italian Sarcoma Group and the Spanish Sarcoma Group. J Clin Oncol. 2012 Mar 10; 30(8):850-6. Gronchi A, Frustaci S, Mercuri M, Martin J, Lopez-Pousa A, Verderio P, Mariani L, Valagussa P, Miceli R, Stacchiotti S, Dei Tos AP, De Paoli A, Longhi A, Poveda A, Quagliuolo V, Comandone A, Casali PG, Picci P. PMID: 22312103.
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    190. Evicase: an evidence-based case structuring approach for personalized healthcare. Stud Health Technol Inform. 2012; 180:604-8. Carmeli B, Casali P, Goldbraich A, Goldsteen A, Kent C, Licitra L, Locatelli P, Restifo N, Rinott R, Sini E, Torresani M, Waks Z. PMID: 22874262.
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    191. Automatic detection of inconsistencies between free text and coded data in Sarcoma discharge letters. Stud Health Technol Inform. 2012; 180:661-6. Rinott R, Torresani M, Bertulli R, Goldsteen A, Casali P, Carmeli B, Slonim N. PMID: 22874274.
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    192. Patterns of care, prognosis, and survival in patients with metastatic gastrointestinal stromal tumors (GIST) refractory to first-line imatinib and second-line sunitinib. Ann Surg Oncol. 2012 May; 19(5):1551-9. Italiano A, Cioffi A, Coco P, Maki RG, Schöffski P, Rutkowski P, Le Cesne A, Duffaud F, Adenis A, Isambert N, Bompas E, Blay JY, Casali P, Keohan ML, Toulmonde M, Antonescu CR, Debiec-Rychter M, Coindre JM, Bui B. PMID: 22065192.
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    193. Natural history of imatinib-naive GISTs: a retrospective analysis of 929 cases with long-term follow-up and development of a survival nomogram based on mitotic index and size as continuous variables. Am J Surg Pathol. 2011 Nov; 35(11):1646-56. Rossi S, Miceli R, Messerini L, Bearzi I, Mazzoleni G, Capella C, Arrigoni G, Sonzogni A, Sidoni A, Toffolatti L, Laurino L, Mariani L, Vinaccia V, Gnocchi C, Gronchi A, Casali PG, Dei Tos AP. PMID: 21997685.
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    194. Receptor tyrosine kinase pathway analysis sheds light on similarities between clear-cell sarcoma and metastatic melanoma. Genes Chromosomes Cancer. 2012 Feb; 51(2):111-26. Negri T, Brich S, Conca E, Bozzi F, Orsenigo M, Stacchiotti S, Alberghini M, Mauro V, Gronchi A, Dusio GF, Pelosi G, Picci P, Casali PG, Pierotti MA, Pilotti S. PMID: 22045652.
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    195. Rare cancers are not so rare: the rare cancer burden in Europe. Eur J Cancer. 2011 Nov; 47(17):2493-511. Gatta G, van der Zwan JM, Casali PG, Siesling S, Dei Tos AP, Kunkler I, Otter R, Licitra L, Mallone S, Tavilla A, Trama A, Capocaccia R, RARECARE working group . PMID: 22033323.
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    196. Trabectedin in advanced uterine leiomyosarcomas: a retrospective case series analysis from two reference centers. Gynecol Oncol. 2011 Dec; 123(3):553-6. Sanfilippo R, Grosso F, Jones RL, Banerjee S, Pilotti S, D'Incalci M, Dei Tos AP, Raspagliesi F, Judson I, Casali PG. PMID: 21917307.
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    197. Uterine sarcomas: a multidisciplinary challenge. Eur J Cancer. 2011 Sep; 47 Suppl 3:S326-7. Casali PG, Sanfilippo R. PMID: 21944001.
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    198. Systemic therapy options for unresectable and metastatic chordomas. Curr Oncol Rep. 2011 Aug; 13(4):323-30. Stacchiotti S, Casali PG. PMID: 21584646.
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    199. Surgical technique, morbidity, and outcome of primary retroperitoneal sarcoma involving inferior vena cava. Ann Surg Oncol. 2012 Feb; 19(2):511-8. Fiore M, Colombo C, Locati P, Berselli M, Radaelli S, Morosi C, Casali PG, Gronchi A. PMID: 21792507.
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    200. A new journal... on spindle cells. Clin Sarcoma Res. 2011 Jul 25; 1(1):1. Casali PG, Dei Tos AP. PMID: 22613678.
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    201. AID dysregulation in lupus-prone MRL/Fas(lpr/lpr) mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4. Autoimmunity. 2011 Dec; 44(8):585-98. White CA, Seth Hawkins J, Pone EJ, Yu ES, Al-Qahtani A, Mai T, Zan H, Casali P. PMID: 21585311.
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    202. Dermatofibrosarcoma protuberans-derived fibrosarcoma: clinical history, biological profile and sensitivity to imatinib. Int J Cancer. 2011 Oct 01; 129(7):1761-72. Stacchiotti S, Pedeutour F, Negri T, Conca E, Marrari A, Palassini E, Collini P, Keslair F, Morosi C, Gronchi A, Pilotti S, Casali PG. PMID: 21128251.
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    203. Imatinib response in two GIST patients carrying two hitherto functionally uncharacterized PDGFRA mutations: an imaging, biochemical and molecular modeling study. Int J Cancer. 2011 Feb 15; 128(4):983-90. Dileo P, Pricl S, Tamborini E, Negri T, Stacchiotti S, Gronchi A, Posocco P, Laurini E, Coco P, Fumagalli E, Casali PG, Pilotti S. PMID: 20473908.
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    204. ERCC5/XPG, ERCC1, and BRCA1 gene status and clinical benefit of trabectedin in patients with soft tissue sarcoma. Cancer. 2011 Aug 01; 117(15):3445-56. Italiano A, Laurand A, Laroche A, Casali P, Sanfilippo R, Le Cesne A, Judson I, Blay JY, Ray-Coquard I, Bui B, Coindre JM, Nieto A, Tercero JC, Jimeno J, Robert J, Pourquier P. PMID: 21287534.
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    205. Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions. Mol Immunol. 2011 Jan; 48(4):610-22. Zan H, Zhang J, Al-Qahtani A, Pone EJ, White CA, Lee D, Yel L, Mai T, Casali P. PMID: 21111482.
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    206. A phase 2 trial of imatinib mesylate in patients with recurrent nonresectable chondrosarcomas expressing platelet-derived growth factor receptor-a or -ß: An Italian Sarcoma Group study. Cancer. 2011 Feb 15; 117(4):826-31. Grignani G, Palmerini E, Stacchiotti S, Boglione A, Ferraresi V, Frustaci S, Comandone A, Casali PG, Ferrari S, Aglietta M. PMID: 20925044.
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    207. Molecular and clinicopathologic characterization of gastrointestinal stromal tumors (GISTs) of small size. Am J Surg Pathol. 2010 Oct; 34(10):1480-91. Rossi S, Gasparotto D, Toffolatti L, Pastrello C, Gallina G, Marzotto A, Sartor C, Barbareschi M, Cantaloni C, Messerini L, Bearzi I, Arrigoni G, Mazzoleni G, Fletcher JA, Casali PG, Talamini R, Maestro R, Maestra R, Dei Tos AP. PMID: 20861712.
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    208. Myxofibrosarcoma: prognostic factors and survival in a series of patients treated at a single institution. Ann Surg Oncol. 2011 Mar; 18(3):720-5. Sanfilippo R, Miceli R, Grosso F, Fiore M, Puma E, Pennacchioli E, Barisella M, Sangalli C, Mariani L, Casali PG, Gronchi A. PMID: 20878245.
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    209. Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutation. J Biol Chem. 2010 Nov 26; 285(48):37797-810. Mai T, Zan H, Zhang J, Hawkins JS, Xu Z, Casali P. PMID: 20855884.
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    210. Specific cross-reaction of anti-dsDNA antibody with platelet integrin GPIIIa49-66. Autoimmunity. 2010 Dec; 43(8):682-9. Zhang W, Dang S, Wang J, Nardi MA, Zan H, Casali P, Li Z. PMID: 20828249.
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    211. PML down-regulation in soft tissue sarcomas. J Cell Physiol. 2010 Sep; 224(3):644-8. Vincenzi B, Perrone G, Santini D, Grosso F, Silletta M, Frezza A, Rossi S, Russo A, Rabitti C, Gebbia N, Badalamenti G, Casali P, Muda AO, Dei Tos AP, Tonini G. PMID: 20578240.
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    212. 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination. Nat Struct Mol Biol. 2010 Sep; 17(9):1124-35. Xu Z, Fulop Z, Wu G, Pone EJ, Zhang J, Mai T, Thomas LM, Al-Qahtani A, White CA, Park SR, Steinacker P, Li Z, Yates J, Herron B, Otto M, Zan H, Fu H, Casali P. PMID: 20729863.
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    213. Novel models of myxoid liposarcoma xenografts mimicking the biological and pharmacologic features of human tumors. Clin Cancer Res. 2010 Oct 15; 16(20):4958-67. Frapolli R, Tamborini E, Virdis E, Bello E, Tarantino E, Marchini S, Grosso F, Sanfilippo R, Gronchi A, Tercero JC, Peloso G, Casali P, Pilotti S, D'Incalci M. PMID: 20732964.
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    214. Fluorescence in situ hybridization analysis and immunophenotyping of c-Kit/PDGFRA and Bcl-2 expression in gastrointestinal stromal tumors. Anal Quant Cytol Histol. 2010 Aug; 32(4):225-33. Orsenigo M, Brich S, Riva C, Conca E, Bertulli R, Dileo P, Gronchi A, Casali PG, Pierotti MA, Tamborini E, Pilotti S. PMID: 21434524.
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    215. Alveolar soft part sarcoma: clinical presentation, treatment, and outcome in a series of 33 patients at a single institution. Ann Surg Oncol. 2010 Dec; 17(12):3229-33. Pennacchioli E, Fiore M, Collini P, Radaelli S, Dileo P, Stacchiotti S, Casali PG, Gronchi A. PMID: 20593242.
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    216. Trabectedin therapy for sarcomas. Curr Opin Oncol. 2010 Jul; 22(4):342-6. Casali PG, Sanfilippo R, D'Incalci M. PMID: 20489618.
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    217. Do rare cancers deserve specific strategies for cancer research? Lancet Oncol. 2010 Jun; 11(6):506-7. Casali PG. PMID: 20522374.
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    218. Aggressive surgery in retroperitoneal soft tissue sarcoma carried out at high-volume centers is safe and is associated with improved local control. Ann Surg Oncol. 2010 Jun; 17(6):1507-14. Bonvalot S, Miceli R, Berselli M, Causeret S, Colombo C, Mariani L, Bouzaiene H, Le Péchoux C, Casali PG, Le Cesne A, Fiore M, Gronchi A. PMID: 20393803.
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    219. Histology-specific nomogram for primary retroperitoneal soft tissue sarcoma. Cancer. 2010 May 15; 116(10):2429-36. Ardoino I, Miceli R, Berselli M, Mariani L, Biganzoli E, Fiore M, Collini P, Stacchiotti S, Casali PG, Gronchi A. PMID: 20209615.
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    220. Sunitinib malate and figitumumab in solitary fibrous tumor: patterns and molecular bases of tumor response. . 2010 May; 9(5):1286-97. Stacchiotti S, Negri T, Palassini E, Conca E, Gronchi A, Morosi C, Messina A, Pastorino U, Pierotti MA, Casali PG, Pilotti S. PMID: 20457621.
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    221. Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells. Cancer Res. 2010 Mar 15; 70(6):2235-44. Germano G, Frapolli R, Simone M, Tavecchio M, Erba E, Pesce S, Pasqualini F, Grosso F, Sanfilippo R, Casali PG, Gronchi A, Virdis E, Tarantino E, Pilotti S, Greco A, Nebuloni M, Galmarini CM, Tercero JC, Mantovani A, D'Incalci M, Allavena P. PMID: 20215499.
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    222. Extremity soft tissue sarcoma in a series of patients treated at a single institution: local control directly impacts survival. Ann Surg. 2010 Mar; 251(3):506-11. Gronchi A, Lo Vullo S, Colombo C, Collini P, Stacchiotti S, Mariani L, Fiore M, Casali PG. PMID: 20130465.
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    223. Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas. Neuro Oncol. 2010 Aug; 12(8):776-89. Tamborini E, Virdis E, Negri T, Orsenigo M, Brich S, Conca E, Gronchi A, Stacchiotti S, Manenti G, Casali PG, Pierotti MA, Pilotti S. PMID: 20164240.
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    224. Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses. Crit Rev Immunol. 2010; 30(1):1-29. Pone EJ, Zan H, Zhang J, Al-Qahtani A, Xu Z, Casali P. PMID: 20370617.
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    225. Chordoma of the mobile spine and sacrum: a retrospective analysis of a series of patients surgically treated at two referral centers. Ann Surg Oncol. 2010 Jan; 17(1):211-9. Stacchiotti S, Casali PG, Lo Vullo S, Mariani L, Palassini E, Mercuri M, Alberghini M, Pilotti S, Zanella L, Gronchi A, Picci P. PMID: 19847568.
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    226. International collaborations in cancer control and the Third International Cancer Control Congress. Tumori. 2009 Sep-Oct; 95(5):579-96. Micheli A, Sanz N, Mwangi-Powell F, Coleman MP, Neal C, Ullrich A, Travado L, Santini LA, Grassi L, De Lorenzo F, Costa A, Dangou JM, Bisanti L, Seniori Costantini A, Abu-Rmeileh N, Kamal M, Federico M, Saracci R, Rennert G, Stefanini A, Cavalli F, Cazap E, Redmond K, O'Reilly S, Muti P, Casali P, Gatta G, Ferrari A, Koifman S, Bah E, Pastore G, Barr R, Lombardo C, Frazzingaro C, Ciampichini R, Baili P, ICCC-3 Session B Group . PMID: 19999949.
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    227. A phase I study of single-agent nilotinib or in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors. Clin Cancer Res. 2009 Sep 15; 15(18):5910-6. Demetri GD, Casali PG, Blay JY, von Mehren M, Morgan JA, Bertulli R, Ray-Coquard I, Cassier P, Davey M, Borghaei H, Pink D, Debiec-Rychter M, Cheung W, Bailey SM, Veronese ML, Reichardt A, Fumagalli E, Reichardt P. PMID: 19723647.
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    228. Translocation-related sarcomas. Semin Oncol. 2009 Aug; 36(4):312-23. Mertens F, Antonescu CR, Hohenberger P, Ladanyi M, Modena P, D'Incalci M, Casali PG, Aglietta M, Alvegård T. PMID: 19664492.
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    229. Absence of progression as assessed by response evaluation criteria in solid tumors predicts survival in advanced GI stromal tumors treated with imatinib mesylate: the intergroup EORTC-ISG-AGITG phase III trial. J Clin Oncol. 2009 Aug 20; 27(24):3969-74. Le Cesne A, Van Glabbeke M, Verweij J, Casali PG, Findlay M, Reichardt P, Issels R, Judson I, Schoffski P, Leyvraz S, Bui B, Hogendoorn PC, Sciot R, Blay JY. PMID: 19620483.
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    230. Desmoid-type fibromatosis: a front-line conservative approach to select patients for surgical treatment. Ann Surg Oncol. 2009 Sep; 16(9):2587-93. Fiore M, Rimareix F, Mariani L, Domont J, Collini P, Le Péchoux C, Casali PG, Le Cesne A, Gronchi A, Bonvalot S. PMID: 19568815.
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    231. HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation. Nat Immunol. 2009 May; 10(5):540-50. Park SR, Zan H, Pal Z, Zhang J, Al-Qahtani A, Pone EJ, Xu Z, Mai T, Casali P. PMID: 19363484.
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    232. Adjuvant treatment of GIST with imatinib: solid ground or still quicksand? A comment on behalf of the EORTC Soft Tissue and Bone Sarcoma Group, the Italian Sarcoma Group, the NCRI Sarcoma Clinical Studies Group (UK), the Japanese Study Group on GIST, the French Sarcoma Group and the Spanish Sarcoma Group (GEIS). Eur J Cancer. 2009 May; 45(7):1103-1106. Gronchi A, Judson I, Nishida T, Poveda A, Martin J, Reichardt P, Casali PG, Cesne AL, Hohenberger P, Blay JY. PMID: 19286368.
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    233. Resection of uninvolved adjacent organs can be part of surgery for retroperitoneal soft tissue sarcoma. J Clin Oncol. 2009 Apr 20; 27(12):2106-7; author reply 2107-8. Gronchi A, Bonvalot S, Le Cesne A, Casali PG. PMID: 19273692.
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    234. High-grade soft-tissue sarcomas: tumor response assessment--pilot study to assess the correlation between radiologic and pathologic response by using RECIST and Choi criteria. Radiology. 2009 May; 251(2):447-56. Stacchiotti S, Collini P, Messina A, Morosi C, Barisella M, Bertulli R, Piovesan C, Dileo P, Torri V, Gronchi A, Casali PG. PMID: 19261927.
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    235. Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors. . 2009 Feb; 8(2):449-57. Forni C, Minuzzo M, Virdis E, Tamborini E, Simone M, Tavecchio M, Erba E, Grosso F, Gronchi A, Aman P, Casali P, D'Incalci M, Pilotti S, Mantovani R. PMID: 19190116.
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    236. Response to sunitinib malate in advanced alveolar soft part sarcoma. Clin Cancer Res. 2009 Feb 01; 15(3):1096-104. Stacchiotti S, Tamborini E, Marrari A, Brich S, Rota SA, Orsenigo M, Crippa F, Morosi C, Gronchi A, Pierotti MA, Casali PG, Pilotti S. PMID: 19188185.
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    237. Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somatic hypermutation and class switch DNA recombination. Autoimmunity. 2009 Feb; 42(2):89-103. Zan H, Zhang J, Ardeshna S, Xu Z, Park SR, Casali P. PMID: 19156553.
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    238. Is autophagy rather than apoptosis the regression driver in imatinib-treated gastrointestinal stromal tumors? Transl Oncol. 2008 Dec; 1(4):177-86. Miselli F, Negri T, Gronchi A, Losa M, Conca E, Brich S, Fumagalli E, Fiore M, Casali PG, Pierotti MA, Tamborini E, Pilotti S. PMID: 19043528.
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    239. Aggressive surgical policies in a retrospectively reviewed single-institution case series of retroperitoneal soft tissue sarcoma patients. J Clin Oncol. 2009 Jan 01; 27(1):24-30. Gronchi A, Lo Vullo S, Fiore M, Mussi C, Stacchiotti S, Collini P, Lozza L, Pennacchioli E, Mariani L, Casali PG. PMID: 19047283.
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    240. The prognostic impact of dedifferentiation in retroperitoneal liposarcoma: a series of surgically treated patients at a single institution. Cancer. 2008 Oct 01; 113(7):1657-65. Mussi C, Collini P, Miceli R, Barisella M, Mariani L, Fiore M, Casali PG, Gronchi A. PMID: 18704991.
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    241. The consensus statement on the locoregional treatment of abdominal sarcomatosis. J Surg Oncol. 2008 Sep 15; 98(4):291-4. Rossi CR, Casali P, Kusamura S, Baratti D, Deraco M. PMID: 18726899.
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    242. AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID. Mol Immunol. 2008 Nov; 46(1):45-61. Zan H, Casali P. PMID: 18760480.
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    243. A role for DRAK2 in the germinal center reaction and the antibody response. Autoimmunity. 2008 Aug; 41(5):341-52. Al-Qahtani A, Xu Z, Zan H, Walsh CM, Casali P. PMID: 18568639.
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    244. Epithelioid sarcoma: prognostic factors and survival in a series of patients treated at a single institution. Ann Surg Oncol. 2007 Dec; 14(12):3542-51. Baratti D, Pennacchioli E, Casali PG, Bertulli R, Lozza L, Olmi P, Collini P, Radaelli S, Fiore M, Gronchi A. PMID: 17909905.
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    245. Combined modalities approach for localized adult extremity soft-tissue sarcoma. Expert Rev Anticancer Ther. 2007 Aug; 7(8):1135-44. Gronchi A, Olmi P, Casali PG. PMID: 18028022.
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    246. NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST)--update of the NCCN clinical practice guidelines. J Natl Compr Canc Netw. 2007 Jul; 5 Suppl 2:S1-29; quiz S30. Demetri GD, Benjamin RS, Blanke CD, Blay JY, Casali P, Choi H, Corless CL, Debiec-Rychter M, DeMatteo RP, Ettinger DS, Fisher GA, Fletcher CD, Gronchi A, Hohenberger P, Hughes M, Joensuu H, Judson I, Le Cesne A, Maki RG, Morse M, Pappo AS, Pisters PW, Raut CP, Reichardt P, Tyler DS, Van den Abbeele AD, von Mehren M, Wayne JD, Zalcberg J, NCCN Task Force . PMID: 17624289.
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    247. Chordoma. Curr Opin Oncol. 2007 Jul; 19(4):367-70. Casali PG, Stacchiotti S, Sangalli C, Olmi P, Gronchi A. PMID: 17545801.
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    248. Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study. Lancet Oncol. 2007 Jul; 8(7):595-602. Grosso F, Jones RL, Demetri GD, Judson IR, Blay JY, Le Cesne A, Sanfilippo R, Casieri P, Collini P, Dileo P, Spreafico C, Stacchiotti S, Tamborini E, Tercero JC, Jimeno J, D'Incalci M, Gronchi A, Fletcher JA, Pilotti S, Casali PG. PMID: 17586092.
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    249. A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake. J Clin Endocrinol Metab. 2007 Sep; 92(9):3531-4. Mannavola D, Coco P, Vannucchi G, Bertuelli R, Carletto M, Casali PG, Beck-Peccoz P, Fugazzola L. PMID: 17595247.
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    250. Myxoid/round cell and pleomorphic liposarcomas: prognostic factors and survival in a series of patients treated at a single institution. Cancer. 2007 Jun 15; 109(12):2522-31. Fiore M, Grosso F, Lo Vullo S, Pennacchioli E, Stacchiotti S, Ferrari A, Collini P, Lozza L, Mariani L, Casali PG, Gronchi A. PMID: 17510918.
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    251. c-Kit/PDGFRA gene status alterations possibly related to primary imatinib resistance in gastrointestinal stromal tumors. Clin Cancer Res. 2007 Apr 15; 13(8):2369-77. Miselli FC, Casieri P, Negri T, Orsenigo M, Lagonigro MS, Gronchi A, Fiore M, Casali PG, Bertulli R, Carbone A, Pierotti MA, Tamborini E, Pilotti S. PMID: 17438095.
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    252. Imatinib does not induce cardiac left ventricular failure in gastrointestinal stromal tumours patients: analysis of EORTC-ISG-AGITG study 62005. Eur J Cancer. 2007 Apr; 43(6):974-8. Verweij J, Casali PG, Kotasek D, Le Cesne A, Reichard P, Judson IR, Issels R, van Oosterom AT, Van Glabbeke M, Blay JY. PMID: 17336514.
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    253. Surgery of residual disease following molecular-targeted therapy with imatinib mesylate in advanced/metastatic GIST. Ann Surg. 2007 Mar; 245(3):341-6. Gronchi A, Fiore M, Miselli F, Lagonigro MS, Coco P, Messina A, Pilotti S, Casali PG. PMID: 17435538.
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    254. Extremity soft tissue sarcoma: adding to the prognostic meaning of local failure. Ann Surg Oncol. 2007 May; 14(5):1583-90. Gronchi A, Miceli R, Fiore M, Collini P, Lozza L, Grosso F, Mariani L, Casali PG. PMID: 17260106.
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    255. DNA replication to aid somatic hypermutation. Adv Exp Med Biol. 2007; 596:111-27. Xu Z, Zan H, Pal Z, Casali P. PMID: 17338180.
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    256. Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination. Crit Rev Immunol. 2007; 27(4):367-97. Xu Z, Pone EJ, Al-Qahtani A, Park SR, Zan H, Casali P. PMID: 18197815.
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    257. Postoperative radiotherapy for synovial sarcoma of the head and neck during pregnancy: clinical and technical management and fetal dose estimates. Tumori. 2007 Jan-Feb; 93(1):45-52. Orlandi E, Zonca G, Pignoli E, Stucchi C, Borroni M, Collini P, Cantù G, Casali PG, Grosso F, Cerrotta A, Fallai C, Olmi P. PMID: 17455871.
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    258. Molecular and biochemical analyses of platelet-derived growth factor receptor (PDGFR) B, PDGFRA, and KIT receptors in chordomas. Clin Cancer Res. 2006 Dec 01; 12(23):6920-8. Tamborini E, Miselli F, Negri T, Lagonigro MS, Staurengo S, Dagrada GP, Stacchiotti S, Pastore E, Gronchi A, Perrone F, Carbone A, Pierotti MA, Casali PG, Pilotti S. PMID: 17145809.
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    259. Advanced extremity soft tissue sarcoma: prognostic effect of isolated limb perfusion in a series of 88 patients treated at a single institution. Ann Surg Oncol. 2007 Feb; 14(2):553-9. Pennacchioli E, Deraco M, Mariani L, Fiore M, Mussi C, Collini P, Olmi P, Casali PG, Santinami M, Gronchi A. PMID: 17122991.
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    260. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet. 2006 Oct 14; 368(9544):1329-38. Demetri GD, van Oosterom AT, Garrett CR, Blackstein ME, Shah MH, Verweij J, McArthur G, Judson IR, Heinrich MC, Morgan JA, Desai J, Fletcher CD, George S, Bello CL, Huang X, Baum CM, Casali PG. PMID: 17046465.
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    261. Malignant peripheral nerve sheath tumors: prognostic factors and survival in a series of patients treated at a single institution. Cancer. 2006 Sep 01; 107(5):1065-74. Anghileri M, Miceli R, Fiore M, Mariani L, Ferrari A, Mussi C, Lozza L, Collini P, Olmi P, Casali PG, Pilotti S, Gronchi A. PMID: 16881077.
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    262. Predicting toxicities for patients with advanced gastrointestinal stromal tumours treated with imatinib: a study of the European Organisation for Research and Treatment of Cancer, the Italian Sarcoma Group, and the Australasian Gastro-Intestinal Trials Group (EORTC-ISG-AGITG). Eur J Cancer. 2006 Sep; 42(14):2277-85. Van Glabbeke M, Verweij J, Casali PG, Simes J, Le Cesne A, Reichardt P, Issels R, Judson IR, van Oosterom AT, Blay JY. PMID: 16876399.
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    263. DNA repair in antibody somatic hypermutation. Trends Immunol. 2006 Jul; 27(7):313-21. Casali P, Pal Z, Xu Z, Zan H. PMID: 16737852.
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    264. A role for the MutL mismatch repair Mlh3 protein in immunoglobulin class switch DNA recombination and somatic hypermutation. J Immunol. 2006 May 01; 176(9):5426-37. Wu X, Tsai CY, Patam MB, Zan H, Chen JP, Lipkin SM, Casali P. PMID: 16622010.
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    265. KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours. Eur J Cancer. 2006 May; 42(8):1093-103. Debiec-Rychter M, Sciot R, Le Cesne A, Schlemmer M, Hohenberger P, van Oosterom AT, Blay JY, Leyvraz S, Stul M, Casali PG, Zalcberg J, Verweij J, Van Glabbeke M, Hagemeijer A, Judson I, EORTC Soft Tissue and Bone Sarcoma Group , Italian Sarcoma Group , Australasian GastroIntestinal Trials Group . PMID: 16624552.
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    266. Reduced tetanus antibody titers in overweight children. Autoimmunity. 2006 Mar; 39(2):137-41. Eliakim A, Schwindt C, Swindt C, Zaldivar F, Casali P, Cooper DM. PMID: 16698670.
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    267. Prognostic analysis of clinicopathologic factors in 49 patients with diffuse malignant peritoneal mesothelioma treated with cytoreductive surgery and intraperitoneal hyperthermic perfusion. Ann Surg Oncol. 2006 Feb; 13(2):229-37. Deraco M, Nonaka D, Baratti D, Casali P, Rosai J, Younan R, Salvatore A, Cabras Ad AD, Kusamura S. PMID: 16444562.
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    268. Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells. Mol Immunol. 2006 Apr; 43(11):1817-26. Komori A, Xu Z, Wu X, Zan H, Casali P. PMID: 16412510.
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    269. Prognostic effect of re-excision in adult soft tissue sarcoma of the extremity. Ann Surg Oncol. 2006 Jan; 13(1):110-7. Fiore M, Casali PG, Miceli R, Mariani L, Bertulli R, Lozza L, Collini P, Olmi P, Mussi C, Gronchi A. PMID: 16372156.
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    270. Diffuse malignant mesothelioma of the peritoneum: a clinicopathological study of 35 patients treated locoregionally at a single institution. Cancer. 2005 Nov 15; 104(10):2181-8. Nonaka D, Kusamura S, Baratti D, Casali P, Cabras AD, Younan R, Rosai J, Deraco M. PMID: 16206294.
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    271. Dermatofibrosarcoma protuberans treated at a single institution: a surgical disease with a high cure rate. J Clin Oncol. 2005 Oct 20; 23(30):7669-75. Fiore M, Miceli R, Mussi C, Lo Vullo S, Mariani L, Lozza L, Collini P, Olmi P, Casali PG, Gronchi A. PMID: 16234529.
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    272. The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation. EMBO J. 2005 Nov 02; 24(21):3757-69. Zan H, Shima N, Xu Z, Al-Qahtani A, Evinger Iii AJ, Zhong Y, Schimenti JC, Casali P. PMID: 16222339.
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    273. Etoposide, doxorubicin and cisplatin plus mitotane in the treatment of advanced adrenocortical carcinoma: a large prospective phase II trial. Endocr Relat Cancer. 2005 Sep; 12(3):657-66. Berruti A, Terzolo M, Sperone P, Pia A, Della Casa S, Gross DJ, Carnaghi C, Casali P, Porpiglia F, Mantero F, Reimondo G, Angeli A, Dogliotti L. PMID: 16172198.
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    274. Initial and late resistance to imatinib in advanced gastrointestinal stromal tumors are predicted by different prognostic factors: a European Organisation for Research and Treatment of Cancer-Italian Sarcoma Group-Australasian Gastrointestinal Trials Group study. J Clin Oncol. 2005 Aug 20; 23(24):5795-804. Van Glabbeke M, Verweij J, Casali PG, Le Cesne A, Hohenberger P, Ray-Coquard I, Schlemmer M, van Oosterom AT, Goldstein D, Sciot R, Hogendoorn PC, Brown M, Bertulli R, Judson IR. PMID: 16110036.
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    275. Outcome of patients with advanced gastro-intestinal stromal tumours crossing over to a daily imatinib dose of 800 mg after progression on 400 mg. Eur J Cancer. 2005 Aug; 41(12):1751-7. Zalcberg JR, Verweij J, Casali PG, Le Cesne A, Reichardt P, Blay JY, Schlemmer M, Van Glabbeke M, Brown M, Judson IR, EORTC Soft Tissue and Bone Sarcoma Group, the Italian Sarcoma Group , Australasian Gastrointestinal Trials Group . PMID: 16098458.
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    276. Adjuvant chemotherapy for soft tissue sarcoma. Curr Opin Oncol. 2005 Jul; 17(4):361-5. Casali PG, Picci P. PMID: 15933469.
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    277. DNA lesions and repair in immunoglobulin class switch recombination and somatic hypermutation. Ann N Y Acad Sci. 2005 Jun; 1050:146-62. Xu Z, Fulop Z, Zhong Y, Evinger AJ, Zan H, Casali P. PMID: 16014529.
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    278. Validation and adaptation of a nomogram for predicting the survival of patients with extremity soft tissue sarcoma using a three-grade system. Cancer. 2005 Jan 15; 103(2):402-8. Mariani L, Miceli R, Kattan MW, Brennan MF, Colecchia M, Fiore M, Casali PG, Gronchi A. PMID: 15578681.
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    279. Carney triad: case report and molecular analysis of gastric tumor. Hum Pathol. 2005 Jan; 36(1):112-6. Diment J, Tamborini E, Casali P, Gronchi A, Carney JA, Colecchia M. PMID: 15712189.
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    280. Class switching and Myc translocation: how does DNA break? Nat Immunol. 2004 Nov; 5(11):1101-3. Casali P, Zan H. PMID: 15496946.
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    281. Imatinib mesylate in chordoma. Cancer. 2004 Nov 01; 101(9):2086-97. Casali PG, Messina A, Stacchiotti S, Tamborini E, Crippa F, Gronchi A, Orlandi R, Ripamonti C, Spreafico C, Bertieri R, Bertulli R, Colecchia M, Fumagalli E, Greco A, Grosso F, Olmi P, Pierotti MA, Pilotti S. PMID: 15372471.
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    282. Ongoing immunoglobulin class switch DNA recombination in lupus B cells: analysis of switch regulatory regions. Autoimmunity. 2004 Sep-Nov; 37(6-7):431-443. Liu S, Cerutti A, Casali P, Crow MK. PMID: 15621569.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    283. Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial. Lancet. 2004 Sep 25-Oct 1; 364(9440):1127-34. Verweij J, Casali PG, Zalcberg J, LeCesne A, Reichardt P, Blay JY, Issels R, van Oosterom A, Hogendoorn PC, Van Glabbeke M, Bertulli R, Judson I. PMID: 15451219.
      View in: PubMed   Mentions: 496     Fields:    Translation:HumansCTClinical Trials
    284. Synovial sarcoma: a retrospective analysis of 271 patients of all ages treated at a single institution. Cancer. 2004 Aug 01; 101(3):627-34. Ferrari A, Gronchi A, Casanova M, Meazza C, Gandola L, Collini P, Lozza L, Bertulli R, Olmi P, Casali PG. PMID: 15274077.
      View in: PubMed   Mentions: 86     Fields:    Translation:Humans
    285. The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombination. J Biol Chem. 2004 Oct 01; 279(40):42258-69. Kim EC, Edmonston CR, Wu X, Schaffer A, Casali P. PMID: 15252056.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    286. A new mutation in the KIT ATP pocket causes acquired resistance to imatinib in a gastrointestinal stromal tumor patient. Gastroenterology. 2004 Jul; 127(1):294-9. Tamborini E, Bonadiman L, Greco A, Albertini V, Negri T, Gronchi A, Bertulli R, Colecchia M, Casali PG, Pierotti MA, Pilotti S. PMID: 15236194.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    287. Retroperitoneal soft tissue sarcomas: patterns of recurrence in 167 patients treated at a single institution. Cancer. 2004 Jun 01; 100(11):2448-55. Gronchi A, Casali PG, Fiore M, Mariani L, Lo Vullo S, Bertulli R, Colecchia M, Lozza L, Olmi P, Santinami M, Rosai J. PMID: 15160351.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    288. Expression of ligand-activated KIT and platelet-derived growth factor receptor beta tyrosine kinase receptors in synovial sarcoma. Clin Cancer Res. 2004 Feb 01; 10(3):938-43. Tamborini E, Bonadiman L, Greco A, Gronchi A, Riva C, Bertulli R, Casali PG, Pierotti MA, Pilotti S. PMID: 14871970.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    289. Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome. J Clin Invest. 2003 Dec; 112(11):1644-54. Girardi G, Berman J, Redecha P, Spruce L, Thurman JM, Kraus D, Hollmann TJ, Casali P, Caroll MC, Wetsel RA, Lambris JD, Holers VM, Salmon JE. PMID: 14660741.
      View in: PubMed   Mentions: 176     Fields:    Translation:AnimalsCells
    290. Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution. Cancer. 2003 Aug 01; 98(3):571-80. Ferrari A, Dileo P, Casanova M, Bertulli R, Meazza C, Gandola L, Navarria P, Collini P, Gronchi A, Olmi P, Fossati-Bellani F, Casali PG. PMID: 12879475.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    291. Immunoglobulin somatic hypermutation: double-strand DNA breaks, AID and error-prone DNA repair. J Clin Immunol. 2003 Jul; 23(4):235-46. Wu X, Feng J, Komori A, Kim EC, Zan H, Casali P. PMID: 12959216.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    292. Peritoneal mesothelioma treated by induction chemotherapy, cytoreductive surgery, and intraperitoneal hyperthermic perfusion. J Surg Oncol. 2003 Jul; 83(3):147-53. Deraco M, Casali P, Inglese MG, Baratti D, Pennacchioli E, Bertulli R, Kusamura S. PMID: 12827682.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    293. AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation. Immunity. 2003 Jun; 18(6):727-38. Zan H, Wu X, Komori A, Holloman WK, Casali P. PMID: 12818155.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    294. Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements. J Biol Chem. 2003 Jun 20; 278(25):23141-50. Schaffer A, Kim EC, Wu X, Zan H, Testoni L, Salamon S, Cerutti A, Casali P. PMID: 12672812.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    295. Gastrointestinal stromal tumors: should they be treated with the same systemic chemotherapy as other soft tissue sarcomas? Oncology. 2003; 64(2):186-8. de Pas T, Casali PG, Toma S, Romanini A, Massidda B, Comandone A, Labianca R, Massacesi C, Tucci A, Antimi M, Biasco G, Aglietta M, Apice G, de Braud F, Italian Sarcoma Group . PMID: 12566918.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    296. Diversity and somatic hypermutation of the Ig VHDJH, V kappa J kappa, and V lambda J lambda gene segments in lymphoma B cells: relevance to the origin of the neoplastic B cell clone. Hum Immunol. 2003 Jan; 64(1):69-81. Riboldi P, Ikematsu W, Brambilla B, Caprani C, Gerosa M, Casali P. PMID: 12507816.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    297. Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells. J Immunol. 2002 Dec 01; 169(11):6594-603. Cerutti A, Zan H, Kim EC, Shah S, Schattner EJ, Schaffer A, Casali P. PMID: 12444172.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    298. Chronic lymphocytic leukemia B cells can undergo somatic hypermutation and intraclonal immunoglobulin V(H)DJ(H) gene diversification. J Exp Med. 2002 Sep 02; 196(5):629-39. Gurrieri C, McGuire P, Zan H, Yan XJ, Cerutti A, Albesiano E, Allen SL, Vinciguerra V, Rai KR, Ferrarini M, Casali P, Chiorazzi N. PMID: 12208878.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    299. DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. Nat Immunol. 2002 Sep; 3(9):822-9. Litinskiy MB, Nardelli B, Hilbert DM, He B, Schaffer A, Casali P, Cerutti A. PMID: 12154359.
      View in: PubMed   Mentions: 412     Fields:    Translation:HumansCells
    300. Somatic immunoglobulin hypermutation. Curr Opin Immunol. 2002 Apr; 14(2):235-40. Diaz M, Casali P. PMID: 11869898.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
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