Frances Anne Jurnak

Title(s)Professor Emeritus, Physiology and Biophysics
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-5865
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    COMPLETE AREA DETECTOR SYSTEM FOR BIOTECHNOLOGY RESEARCH
    NIH S10RR005070Jun 14, 1989 - Jun 13, 1990
    Role: Principal Investigator
    BIOCHEMICAL AND STRUCTURAL STUDIES OF ELONGATION FACTORS
    NIH R01GM026895Aug 1, 1979 - Aug 31, 2002
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Pivotal Role of Aldehyde Toxicity in Autism Spectrum Disorder: The Therapeutic Potential of Micronutrient Supplementation. Nutr Metab Insights. 2015; 8(Suppl 1):57-77. Jurnak F. PMID: 27330305.
      View in: PubMed   Mentions:
    2. Dancer perceptions of the cognitive, social, emotional, and physical benefits of modern styles of partnered dancing. Complement Ther Med. 2016 Jun; 26:117-22. Lakes KD, Marvin S, Rowley J, Nicolas MS, Arastoo S, Viray L, Orozco A, Jurnak F. PMID: 27261991.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    3. WIF1, a Wnt pathway inhibitor, regulates SKP2 and c-myc expression leading to G1 arrest and growth inhibition of human invasive urinary bladder cancer cells. . 2009 Feb; 8(2):458-68. Tang Y, Simoneau AR, Liao WX, Yi G, Hope C, Liu F, Li S, Xie J, Holcombe RF, Jurnak FA, Mercola D, Hoang BH, Zi X. PMID: 19174556.
      View in: PubMed   Mentions:
    4. Investigation of folding of purified recombinant GRA1 protein using web based protein disorder servers and trypsin digestion. Protein Pept Lett. 2009; 16(7):834-41. Döskaya M, Caner A, Degirmenci A, Jurnak F, Gürüz Y. PMID: 19601915.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Discerning the Mauve factor, Part 2. Altern Ther Health Med. 2008 May-Jun; 14(3):56-62. McGinnis WR, Audhya T, Walsh WJ, Jackson JA, McLaren-Howard J, Lewis A, Lauda PH, Bibus DM, Jurnak F, Lietha R, Hoffer A. PMID: 18517107.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Discerning the Mauve Factor, Part 1. Altern Ther Health Med. 2008 Mar-Apr; 14(2):40-50. McGinnis WR, Audhya T, Walsh WJ, Jackson JA, McLaren-Howard J, Lewis A, Lauda PH, Bibus DM, Jurnak F, Lietha R, Hoffer A. PMID: 18383989.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    7. Expression of Wnt pathway components frizzled and disheveled in colon cancer arising in patients with inflammatory bowel disease. Oncol Rep. 2007 Sep; 18(3):691-4. You XJ, Bryant PJ, Jurnak F, Holcombe RF. PMID: 17671721.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    8. GRA1 protein vaccine confers better immune response compared to codon-optimized GRA1 DNA vaccine. Vaccine. 2007 Feb 26; 25(10):1824-37. Döskaya M, Kalantari-Dehaghi M, Walsh CM, Hiszczynska-Sawicka E, Davies DH, Felgner PL, Larsen LS, Lathrop RH, Hatfield GW, Schulz JR, Gürüz Y, Jurnak F. PMID: 17234306.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    9. Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu. Acta Crystallogr D Biol Crystallogr. 2006 Nov; 62(Pt 11):1392-400. Heffron SE, Mui S, Aorora A, Abel K, Bergmann E, Jurnak F. PMID: 17057344.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    10. Solving the structure of Escherichia coli elongation factor Tu using a twinned data set. Acta Crystallogr D Biol Crystallogr. 2006 Apr; 62(Pt 4):433-8. Heffron SE, Moeller R, Jurnak F. PMID: 16552145.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    11. Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor. . 2005 Dec; 4(12):1923-35. Yang S, Irani K, Heffron SE, Jurnak F, Meyskens FL. PMID: 16373707.
      View in: PubMed   Mentions:
    12. Resolving the space-group ambiguity of crystals of tomato fruit polygalacturonase. Acta Crystallogr D Biol Crystallogr. 2003 Dec; 59(Pt 12):2088-93. Heffron S, Watkins S, Moeller R, Taban AH, Butowt R, DellaPenna D, Jurnak F. PMID: 14646066.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    13. EF-Tu binding peptides identified, dissected, and affinity optimized by phage display. Chem Biol. 2003 Feb; 10(2):161-8. Murase K, Morrison KL, Tam PY, Stafford RL, Jurnak F, Weiss GA. PMID: 12618188.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    14. Characterization and implications of Ca2+ binding to pectate lyase C. J Biol Chem. 2003 Apr 04; 278(14):12271-7. Herron SR, Scavetta RD, Garrett M, Legner M, Jurnak F. PMID: 12540845.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    15. GE2270A-resistant mutations in elongation factor Tu allow productive aminoacyl-tRNA binding to EF-Tu.GTP.GE2270A complexes. J Mol Biol. 2000 Dec 15; 304(5):995-1005. Zuurmond AM, Martien de Graaf J, Olsthoorn-Tieleman LN, van Duyl BY, Mörhle VG, Jurnak F, Mesters JR, Hilgenfeld R, Kraal B. PMID: 11124042.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    16. Structure and function of pectic enzymes: virulence factors of plant pathogens. Proc Natl Acad Sci U S A. 2000 Aug 01; 97(16):8762-9. Herron SR, Benen JA, Scavetta RD, Visser J, Jurnak F. PMID: 10922032.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    17. Structure of an EF-Tu complex with a thiazolyl peptide antibiotic determined at 2.35 A resolution: atomic basis for GE2270A inhibition of EF-Tu. Biochemistry. 2000 Jan 11; 39(1):37-45. Heffron SE, Jurnak F. PMID: 10625477.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    18. Structure of a plant cell wall fragment complexed to pectate lyase C. Plant Cell. 1999 Jun; 11(6):1081-92. Scavetta RD, Herron SR, Hotchkiss AT, Kita N, Keen NT, Benen JA, Kester HC, Visser J, Jurnak F. PMID: 10368179.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    19. Sequence profile of the parallel beta helix in the pectate lyase superfamily. J Struct Biol. 1998; 122(1-2):223-35. Heffron S, Moe GR, Sieber V, Mengaud J, Cossart P, Vitali J, Jurnak F. PMID: 9724624.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    20. Differential effect of site-directed mutations in pelC on pectate lyase activity, plant tissue maceration, and elicitor activity. J Biol Chem. 1996 Oct 25; 271(43):26529-35. Kita N, Boyd CM, Garrett MR, Jurnak F, Keen NT. PMID: 8900122.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    21. An alpha to beta conformational switch in EF-Tu. Structure. 1996 Oct 15; 4(10):1153-9. Abel K, Yoder MD, Hilgenfeld R, Jurnak F. PMID: 8939740.
      View in: PubMed   Mentions: 55     Fields:    Translation:Cells
    22. The Refined Three-Dimensional Structure of Pectate Lyase E from Erwinia chrysanthemi at 2.2 A Resolution. Plant Physiol. 1996 May; 111(1):73-92. Lietzke SE, Scavetta RD, Yoder MD, Jurnak F. PMID: 12226275.
      View in: PubMed   Mentions: 11     Fields:    
    23. A complex profile of protein elongation: translating chemical energy into molecular movement. Structure. 1996 Mar 15; 4(3):229-38. Abel K, Jurnak F. PMID: 8805530.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    24. Circular dichroism of the parallel beta helical proteins pectate lyase C and E. Proteins. 1995 Sep; 23(1):32-7. Sieber V, Jurnak F, Moe GR. PMID: 8539248.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    25. Structure-based multiple alignment of extracellular pectate lyase sequences. Mol Plant Microbe Interact. 1995 Mar-Apr; 8(2):331-4. Heffron S, Henrissat B, Yoder MD, Lietzke S, Jurnak F. PMID: 7756698.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    26. Functional implications of structure-based sequence alignment of proteins in the extracellular pectate lyase superfamily. Plant Physiol. 1995 Mar; 107(3):963-76. Henrissat B, Heffron SE, Yoder MD, Lietzke SE, Jurnak F. PMID: 7716248.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    27. The Refined Three-Dimensional Structure of Pectate Lyase C from Erwinia chrysanthemi at 2.2 Angstrom Resolution (Implications for an Enzymatic Mechanism). Plant Physiol. 1995 Feb; 107(2):349-364. Yoder MD, Jurnak F. PMID: 12228363.
      View in: PubMed   Mentions: 14     Fields:    
    28. New domain motif: the structure of pectate lyase C, a secreted plant virulence factor. Science. 1993 Jun 04; 260(5113):1503-7. Yoder MD, Keen NT, Jurnak F. PMID: 8502994.
      View in: PubMed   Mentions: 101     Fields:    Translation:Cells
    29. An isotope edited classical Raman difference spectroscopic study of the interactions of guanine nucleotides with elongation factor Tu and H-ras p21. Biochemistry. 1991 Nov 12; 30(45):10914-20. Manor D, Weng GZ, Deng H, Cosloy S, Chen CX, Balogh-Nair V, Delaria K, Jurnak F, Callender R. PMID: 1932015.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    30. Stabilization of the Escherichia coli elongation factor Tu-GTP-aminoacyl-tRNA complex. Arch Biochem Biophys. 1991 Apr; 286(1):207-11. Delaria K, Guillen M, Louie A, Jurnak F. PMID: 1897948.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    31. Genetic engineering, isolation and characterization of a truncated Escherichia coli elongation factor Tu comprising domains 2 and 3. Biochim Biophys Acta. 1990 Oct 23; 1087(2):147-56. Pieper U, Ehbrecht HJ, Fliess A, Schick B, Jurnak F, Pingoud A. PMID: 2223877.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    32. Three-dimensional models of the GDP and GTP forms of the guanine nucleotide domain of Escherichia coli elongation factor Tu. Biochim Biophys Acta. 1990 Aug 27; 1050(1-3):209-14. Jurnak F, Heffron S, Schick B, Delaria K. PMID: 2119811.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    33. Preliminary crystallographic analysis of a complex between tetracycline and the trypsin-modified form of Escherichia coli elongation factor Tu. J Mol Biol. 1990 Apr 05; 212(3):445-7. Mui S, Delaria K, Jurnak F. PMID: 2182884.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    34. Conformational changes involved in the activation of ras p21: implications for related proteins. Cell. 1990 Feb 23; 60(4):525-8. Jurnak F, Heffron S, Bergmann E. PMID: 2105846.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    35. Preparation of Escherichia coli elongation factor Tu-guanosine 5'-triphosphate analogs. Anal Biochem. 1989 Feb 15; 177(1):188-93. Delaria K, Jurnak F. PMID: 2662816.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    36. Kinetic studies of Escherichia coli elongation factor Tu-guanosine 5'-triphosphate-aminoacyl-tRNA complexes. Biochemistry. 1985 Nov 05; 24(23):6433-9. Louie A, Jurnak F. PMID: 3910093.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    37. Structure of the GDP domain of EF-Tu and location of the amino acids homologous to ras oncogene proteins. Science. 1985 Oct 04; 230(4721):32-6. Jurnak F. PMID: 3898365.
      View in: PubMed   Mentions: 123     Fields:    Translation:Cells
    38. Bulk preparation and crystallization of the Escherichia coli elongation factor Tu-Ts complex. Anal Biochem. 1985 Oct; 150(1):243-8. Yoder M, Torres C, Corelli R, Jurnak F. PMID: 3909845.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    39. Induction of elongation factor Tu-GDP crystal polymorphism by polyethylene glycol contaminants. J Mol Biol. 1985 Sep 05; 185(1):215-7. Jurnak F. PMID: 3900422.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    40. Effect of trypsin modification of the Escherichia coli elongation factor Tu on the ternary complex with aminoacyl-tRNA. J Biol Chem. 1985 Jul 25; 260(15):8702-5. Masuda E, Louie A, Jurnak F. PMID: 3894346.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    41. Elongation factor Tu ternary complex binds to small ribosomal subunits in a functionally active state. Biochemistry. 1984 Dec 04; 23(25):6171-8. Langer JA, Jurnak F, Lake JA. PMID: 6395891.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    42. Relative affinities of all Escherichia coli aminoacyl-tRNAs for elongation factor Tu-GTP. J Biol Chem. 1984 Apr 25; 259(8):5010-6. Louie A, Ribeiro NS, Reid BR, Jurnak F. PMID: 6370998.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    43. Biochemical and structural studies of the tetragonal crystalline modification of the Escherichia coli elongation factor Tu. J Biol Chem. 1980 Jul 25; 255(14):6751-7. Jurnak F, McPherson A, Wang AH, Rich A. PMID: 6993478.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    44. Preliminary x-ray diffraction data for tetragonal crystals of trypsinized Escherichia coli elongation factor. J Mol Biol. 1977 Sep; 115(1):103-10. Jurnak F, Rich A, Miller D. PMID: 336895.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
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