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Nesburn, Anthony B

TitleAdjunct Professor
InstitutionUniversity of California, Irvine
DepartmentOphthalmology
Address1001 Health Sciences Road
CA 92697-3950
Phone(949) 824-6892
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    Collapse Research 
    Collapse Research Activities and Funding
    VISION RESEARCH INFRASTRUCTURE DEVELOPMENT GRANT
    NIH/NEI R24EY016663Jun 1, 2005 - May 31, 2011
    Role: Principal Investigator
    Ocular Mucosal Immunity
    NIH/NEI R01EY015225Aug 1, 2004 - Jun 30, 2008
    Role: Principal Investigator
    THERAPEUTIC VACCINES TO REDUCE OCULAR HSV RECURRENCE
    NIH/NEI R01EY009392Jan 1, 1992 - Mar 31, 2005
    Role: Principal Investigator
    OCULAR HERPES AND RECURRENCE
    NIH/NEI R01EY005939Apr 1, 1986 - Mar 31, 1991
    Role: Principal Investigator
    HERPES SIMPLEX OF THE EYE: PATHOGENESIS AND TREATMENT
    NIH/NEI R01EY006398Jun 1, 1985 - Mar 31, 1986
    Role: Principal Investigator
    HERPES SIMPLEX OF THE EYE: PATHOGENESIS AND TREATMENT
    NIH/NEI R01EY000858Sep 30, 1976 - May 31, 1985
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lopes PP, Todorov G, Pham TT, Nesburn A, Bahraoui E, BenMohamed L. Laser Adjuvant-Assisted Peptide Vaccine Promotes Skin Mobilization of Dendritic Cells and Enhances Protective CD8+ TEM and TRM Cell Responses against Herpesvirus Infection and Disease. J Virol. 2018 04 15; 92(8). PMID: 29437976.
      View in: PubMed
    2. Nashine S, Cohen P, Chwa M, Lu S, Nesburn A, Kuppermann BD, Kenney MC. Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage. Cell Death Dis. 2017 07 20; 8(7):e2951. PMID: 28726777.
      View in: PubMed
    3. Srivastava R, Khan AA, Garg S, Syed SA, Furness JN, Vahed H, Pham T, Yu HT, Nesburn A, BenMohamed L. Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocular Herpesvirus Infection. J Virol. 2017 Jan 15; 91(2). PMID: 27847359.
      View in: PubMed
    4. Nesburn A, BenMohamed L. A Tribute to Professor Steven L. Wechsler (1948-2016): The Man and the Scientist. Curr Eye Res. 2017 01; 42(1):161-162. PMID: 27911113.
      View in: PubMed
    5. Nashine S, Chwa M, Kazemian M, Thaker K, Lu S, Nesburn A, Kuppermann BD, Kenney MC. Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids. PLoS One. 2016; 11(8):e0159828. PMID: 27486856; PMCID: PMC4972370.
    6. Thaker K, Chwa M, Atilano SR, Coskun P, Cáceres-Del-Carpio J, Udar N, Boyer DS, Jazwinski SM, Miceli MV, Nesburn A, Kuppermann BD, Kenney MC. Increased expression of ApoE and protection from amyloid-beta toxicity in transmitochondrial cybrids with haplogroup K mtDNA. Neurobiol Dis. 2016 09; 93:64-77. PMID: 27109188.
      View in: PubMed
    7. Srivastava R, Dervillez X, Khan AA, Chentoufi AA, Chilukuri S, Shukr N, Fazli Y, Ong NN, Afifi RE, Osorio N, Geertsema R, Nesburn A, Wechsler SL, BenMohamed L. The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits. J Virol. 2016 Apr; 90(8):3913-3928. PMID: 26842468.
      View in: PubMed
    8. Khan AA, Srivastava R, Chentoufi AA, Geertsema R, Thai NT, Dasgupta G, Osorio N, Kalantari M, Nesburn A, Wechsler SL, BenMohamed L. Therapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of local PD-1+ TIM-3+ CD8+ exhausted T cells. J Virol. 2015 Jul; 89(13):6619-32. PMID: 25878105; PMCID: PMC4468472.
    9. Srivastava R, Khan AA, Huang J, Nesburn A, Wechsler SL, BenMohamed L. A Herpes Simplex Virus Type 1 Human Asymptomatic CD8+ T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a "Humanized" HLA Transgenic Rabbit Model. Invest Ophthalmol Vis Sci. 2015 Jun; 56(6):4013-28. PMID: 26098469; PMCID: PMC4477261.
    10. Atilano SR, Malik D, Chwa M, Cáceres-Del-Carpio J, Nesburn A, Boyer DS, Kuppermann BD, Jazwinski SM, Miceli MV, Wallace DC, Udar N, Kenney MC. Mitochondrial DNA variants can mediate methylation status of inflammation, angiogenesis and signaling genes. Hum Mol Genet. 2015 Aug 15; 24(16):4491-503. PMID: 25964427; PMCID: PMC4512622.
    11. Srivastava R, Khan AA, Spencer D, Vahed H, Lopes PP, Thai NT, Wang C, Pham TT, Huang J, Scarfone VM, Nesburn A, Wechsler SL, BenMohamed L. HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgenic mice against ocular herpes. J Immunol. 2015 Mar 01; 194(5):2232-48. PMID: 25617474; PMCID: PMC4340763.
    12. Khan AA, Srivastava R, Spencer D, Garg S, Fremgen D, Vahed H, Lopes PP, Pham TT, Hewett C, Kuang J, Ong N, Huang L, Scarfone VM, Nesburn A, Wechsler SL, BenMohamed L. Phenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpes. J Virol. 2015 Apr; 89(7):3776-92. PMID: 25609800; PMCID: PMC4403403.
    13. Farid M, Agrawal A, Fremgen D, Tao J, Chuyi H, Nesburn A, BenMohamed L. Age-related Defects in Ocular and Nasal Mucosal Immune System and the Immunopathology of Dry Eye Disease. Ocul Immunol Inflamm. 2016 Jun; 24(3):327-47. PMID: 25535823; PMCID: PMC4478284.
    14. Malik D, Hsu T, Falatoonzadeh P, Cáceres-del-Carpio J, Tarek M, Chwa M, Atilano SR, Ramirez C, Nesburn A, Boyer DS, Kuppermann BD, Jazwinski SM, Miceli MV, Wallace DC, Udar N, Kenney MC. Human retinal transmitochondrial cybrids with J or H mtDNA haplogroups respond differently to ultraviolet radiation: implications for retinal diseases. PLoS One. 2014; 9(2):e99003. PMID: 24919117; PMCID: PMC4053329.
    15. Kenney MC, Chwa M, Atilano SR, Falatoonzadeh P, Ramirez C, Malik D, Tarek M, Cáceres-del-Carpio J, Nesburn A, Boyer DS, Kuppermann BD, Vawter M, Jazwinski SM, Miceli M, Wallace DC, Udar N. Inherited mitochondrial DNA variants can affect complement, inflammation and apoptosis pathways: insights into mitochondrial-nuclear interactions. Hum Mol Genet. 2014 Jul 01; 23(13):3537-51. PMID: 24584571; PMCID: PMC4049308.
    16. Kenney MC, Chwa M, Atilano SR, Falatoonzadeh P, Ramirez C, Malik D, Tarek M, Del Carpio JC, Nesburn A, Boyer DS, Kuppermann BD, Vawter MP, Jazwinski SM, Miceli MV, Wallace DC, Udar N. Molecular and bioenergetic differences between cells with African versus European inherited mitochondrial DNA haplogroups: implications for population susceptibility to diseases. Biochim Biophys Acta. 2014 Feb; 1842(2):208-19. PMID: 24200652; PMCID: PMC4326177.
    17. Dervillez X, Qureshi H, Chentoufi AA, Khan AA, Kritzer E, Yu DC, Diaz OR, Gottimukkala C, Kalantari M, Villacres MC, Scarfone VM, McKinney DM, Sidney J, Sette A, Nesburn A, Wechsler SL, BenMohamed L. Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes. J Immunol. 2013 Nov 15; 191(10):5124-38. PMID: 24101547; PMCID: PMC4057607.
    18. Kenney MC, Chwa M, Atilano SR, Pavlis JM, Falatoonzadeh P, Ramirez C, Malik D, Hsu T, Woo G, Soe K, Nesburn A, Boyer DS, Kuppermann BD, Jazwinski SM, Miceli MV, Wallace DC, Udar N. Mitochondrial DNA variants mediate energy production and expression levels for CFH, C3 and EFEMP1 genes: implications for age-related macular degeneration. PLoS One. 2013; 8(1):e54339. PMID: 23365660; PMCID: PMC3554762.
    19. Kenney MC, Hertzog D, Chak G, Atilano SR, Khatibi N, Soe K, Nobe A, Yang E, Chwa M, Zhu F, Memarzadeh M, King J, Langberg J, Small K, Nesburn A, Boyer DS, Udar N. Mitochondrial DNA haplogroups confer differences in risk for age-related macular degeneration: a case control study. BMC Med Genet. 2013 Jan 09; 14:4. PMID: 23302509; PMCID: PMC3566905.
    20. Chentoufi AA, Dervillez X, Dasgupta G, Nguyen C, Kabbara KW, Jiang X, Nesburn A, Wechsler SL, Benmohamed L. The herpes simplex virus type 1 latency-associated transcript inhibits phenotypic and functional maturation of dendritic cells. Viral Immunol. 2012 Jun; 25(3):204-15. PMID: 22512280; PMCID: PMC3366336.
    21. Dervillez X, Gottimukkala C, Kabbara KW, Nguyen C, Badakhshan T, Kim SM, Nesburn A, Wechsler SL, Benmohamed L. Future of an "Asymptomatic" T-cell Epitope-Based Therapeutic Herpes Simplex Vaccine. Future Virol. 2012 Apr 01; 7(4):371-378. PMID: 22701511.
      View in: PubMed
    22. Chentoufi AA, Kritzer E, Yu DM, Nesburn A, Benmohamed L. Towards a rational design of an asymptomatic clinical herpes vaccine: the old, the new, and the unknown. Clin Dev Immunol. 2012; 2012:187585. PMID: 22548113; PMCID: PMC3324142.
    23. Chentoufi AA, Dervillez X, Rubbo PA, Kuo T, Zhang X, Nagot N, Tuaillon E, Van De Perre P, Nesburn A, Benmohamed L. Current trends in negative immuno-synergy between two sexually transmitted infectious viruses: HIV-1 and HSV-1/2. Curr Trends Immunol. 2012; 13:51-68. PMID: 23355766.
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    24. Chentoufi AA, Kritzer E, Tran MV, Dasgupta G, Lim CH, Yu DC, Afifi RE, Jiang X, Carpenter D, Osorio N, Hsiang C, Nesburn A, Wechsler SL, BenMohamed L. The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism. J Virol. 2011 Sep; 85(17):9127-38. PMID: 21715478; PMCID: PMC3165846.
    25. Dasgupta G, Chentoufi AA, You S, Falatoonzadeh P, Urbano LA, Akhtarmalik A, Nguyen K, Ablabutyan L, Nesburn A, BenMohamed L. Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses. Invest Ophthalmol Vis Sci. 2011 May 17; 52(6):3321-33. PMID: 21273544; PMCID: PMC3109031.
    26. Renaudet O, Dasgupta G, Bettahi I, Shi A, Nesburn A, Dumy P, BenMohamed L. Linear and branched glyco-lipopeptide vaccines follow distinct cross-presentation pathways and generate different magnitudes of antitumor immunity. PLoS One. 2010 Jun 21; 5(6):e11216. PMID: 20574522; PMCID: PMC2888579.
    27. Kenney MC, Atilano SR, Boyer D, Chwa M, Chak G, Chinichian S, Coskun P, Wallace DC, Nesburn A, Udar NS. Characterization of retinal and blood mitochondrial DNA from age-related macular degeneration patients. Invest Ophthalmol Vis Sci. 2010 Aug; 51(8):4289-97. PMID: 20357205.
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    28. Chentoufi AA, Dasgupta G, Christensen ND, Hu J, Choudhury ZS, Azeem A, Jester JV, Nesburn A, Wechsler SL, BenMohamed L. A novel HLA (HLA-A*0201) transgenic rabbit model for preclinical evaluation of human CD8+ T cell epitope-based vaccines against ocular herpes. J Immunol. 2010 Mar 01; 184(5):2561-71. PMID: 20124097; PMCID: PMC3752373.
    29. Chentoufi AA, Dasgupta G, Nesburn A, Bettahi I, Binder NR, Choudhury ZS, Chamberlain WD, Wechsler SL, BenMohamed L. Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization. Clin Vaccine Immunol. 2010 Mar; 17(3):342-53. PMID: 20089796; PMCID: PMC2837957.
    30. Dasgupta G, Nesburn A, Wechsler SL, BenMohamed L. Developing an asymptomatic mucosal herpes vaccine: the present and the future. Future Microbiol. 2010 Jan; 5(1):1-4. PMID: 20020824; PMCID: PMC4512283.
    31. Chentoufi AA, Nesburn A, BenMohamed L. Recent advances in multivalent self adjuvanting glycolipopeptide vaccine strategies against breast cancer. Arch Immunol Ther Exp (Warsz). 2009 Nov-Dec; 57(6):409-23. PMID: 19866342.
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    32. Udar N, Atilano SR, Small K, Nesburn A, Kenney MC. SOD1 haplotypes in familial keratoconus. Cornea. 2009 Sep; 28(8):902-7. PMID: 19654524.
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    33. Dasgupta G, Chentoufi AA, Nesburn A, Wechsler SL, BenMohamed L. New concepts in herpes simplex virus vaccine development: notes from the battlefield. Expert Rev Vaccines. 2009 Aug; 8(8):1023-35. PMID: 19627185; PMCID: PMC2760836.
    34. Udar N, Atilano SR, Memarzadeh M, Boyer DS, Chwa M, Lu S, Maguen B, Langberg J, Coskun P, Wallace DC, Nesburn A, Khatibi N, Hertzog D, Le K, Hwang D, Kenney MC. Mitochondrial DNA haplogroups associated with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2009 Jun; 50(6):2966-74. PMID: 19151382.
      View in: PubMed
    35. Zhang X, Chentoufi AA, Dasgupta G, Nesburn A, Wu M, Zhu X, Carpenter D, Wechsler SL, You S, BenMohamed L. A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge. Mucosal Immunol. 2009 Mar; 2(2):129-143. PMID: 19129756; PMCID: PMC4509510.
    36. Chentoufi AA, Zhang X, Lamberth K, Dasgupta G, Bettahi I, Nguyen A, Wu M, Zhu X, Mohebbi A, Buus S, Wechsler SL, Nesburn A, BenMohamed L. HLA-A*0201-restricted CD8+ cytotoxic T lymphocyte epitopes identified from herpes simplex virus glycoprotein D. J Immunol. 2008 Jan 01; 180(1):426-37. PMID: 18097044.
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    37. Bettahi I, Nesburn A, Yoon S, Zhang X, Mohebbi A, Sue V, Vanderberg A, Wechsler SL, BenMohamed L. Protective immunity against ocular herpes infection and disease induced by highly immunogenic self-adjuvanting glycoprotein D lipopeptide vaccines. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4643-53. PMID: 17898288.
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    38. Nesburn A, Bettahi I, Dasgupta G, Chentoufi AA, Zhang X, You S, Morishige N, Wahlert AJ, Brown DJ, Jester JV, Wechsler SL, BenMohamed L. Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection. J Virol. 2007 Jul; 81(14):7647-61. PMID: 17475646; PMCID: PMC1933381.
    39. Mott KR, Osorio Y, Maguen E, Nesburn A, Wittek AE, Cai S, Chattopadhyay S, Ghiasi H. Role of anti-glycoproteins D (anti-gD) and K (anti-gK) IgGs in pathology of herpes stromal keratitis in humans. Invest Ophthalmol Vis Sci. 2007 May; 48(5):2185-93. PMID: 17460278.
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    40. Narayanan R, Butani V, Boyer DS, Atilano SR, Resende GP, Kim DS, Chakrabarti S, Kuppermann BD, Khatibi N, Chwa M, Nesburn A, Kenney MC. Complement factor H polymorphism in age-related macular degeneration. Ophthalmology. 2007 Jul; 114(7):1327-31. PMID: 17306880.
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    41. Nesburn A, Bettahi I, Zhang X, Zhu X, Chamberlain W, Afifi RE, Wechsler SL, BenMohamed L. Topical/mucosal delivery of sub-unit vaccines that stimulate the ocular mucosal immune system. Ocul Surf. 2006 Oct; 4(4):178-87. PMID: 17146573.
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    42. Udar N, Atilano SR, Brown DJ, Holguin B, Small K, Nesburn A, Kenney MC. SOD1: a candidate gene for keratoconus. Invest Ophthalmol Vis Sci. 2006 Aug; 47(8):3345-51. PMID: 16877401.
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    43. Zhang X, Issagholian A, Berg EA, Fishman JB, Nesburn A, BenMohamed L. Th-cytotoxic T-lymphocyte chimeric epitopes extended by Nepsilon-palmitoyl lysines induce herpes simplex virus type 1-specific effector CD8+ Tc1 responses and protect against ocular infection. J Virol. 2005 Dec; 79(24):15289-301. PMID: 16306600; PMCID: PMC1316035.
    44. Nesburn A, Ramos TV, Zhu X, Asgarzadeh H, Nguyen V, BenMohamed L. Local and systemic B cell and Th1 responses induced following ocular mucosal delivery of multiple epitopes of herpes simplex virus type 1 glycoprotein D together with cytosine-phosphate-guanine adjuvant. Vaccine. 2005 Jan 04; 23(7):873-83. PMID: 15603887.
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    45. Peng W, Jin L, Henderson G, Perng GC, Brick DJ, Nesburn A, Wechsler SL, Jones C. Mapping herpes simplex virus type 1 latency-associated transcript sequences that protect from apoptosis mediated by a plasmid expressing caspase-8. J Neurovirol. 2004 Aug; 10(4):260-5. PMID: 15371157.
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    46. Jin L, Perng GC, Brick DJ, Naito J, Nesburn A, Jones C, Wechsler SL. Methods for detecting the HSV-1 LAT anti-apoptosis activity in virus infected tissue culture cells. J Virol Methods. 2004 Jun 01; 118(1):9-13. PMID: 15158063.
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    47. Henderson G, Perng GC, Nesburn A, Wechsler SL, Jones C. The latency-related gene encoded by bovine herpesvirus 1 can suppress caspase 3 and caspase 9 cleavage during productive infection. J Neurovirol. 2004 Feb; 10(1):64-70. PMID: 14982730.
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    48. Udar N, Kenney MC, Chalukya M, Anderson T, Morales L, Brown D, Nesburn A, Small K. Keratoconus--no association with the transforming growth factor beta-induced gene in a cohort of American patients. Cornea. 2004 Jan; 23(1):13-7. PMID: 14701952.
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    49. Peng W, Henderson G, Perng GC, Nesburn A, Wechsler SL, Jones C. The gene that encodes the herpes simplex virus type 1 latency-associated transcript influences the accumulation of transcripts (Bcl-x(L) and Bcl-x(S)) that encode apoptotic regulatory proteins. J Virol. 2003 Oct; 77(19):10714-8. PMID: 12970460; PMCID: PMC228484.
    50. BenMohamed L, Bertrand G, McNamara CD, Gras-Masse H, Hammer J, Wechsler SL, Nesburn A. Identification of novel immunodominant CD4+ Th1-type T-cell peptide epitopes from herpes simplex virus glycoprotein D that confer protective immunity. J Virol. 2003 Sep; 77(17):9463-73. PMID: 12915561; PMCID: PMC187395.
    51. Ong JM, Zorapapel NC, Aoki AM, Brown DJ, Nesburn A, Rich KA, Kenney CM. Impaired electroretinogram (ERG) response in apolipoprotein E-deficient mice. Curr Eye Res. 2003 Jul; 27(1):15-24. PMID: 12868005.
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    52. Jin L, Peng W, Perng GC, Brick DJ, Nesburn A, Jones C, Wechsler SL. Identification of herpes simplex virus type 1 latency-associated transcript sequences that both inhibit apoptosis and enhance the spontaneous reactivation phenotype. J Virol. 2003 Jun; 77(11):6556-61. PMID: 12743314; PMCID: PMC155006.
    53. Ong JM, Aoki AM, Seigel GM, Sacerio I, Castellon R, Nesburn A, Kenney MC. Oxysterol-induced toxicity in R28 and ARPE-19 cells. Neurochem Res. 2003 Jun; 28(6):883-91. PMID: 12718442.
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    54. Schmidt S, Klaver C, Saunders A, Postel E, De La Paz M, Agarwal A, Small K, Udar N, Ong J, Chalukya M, Nesburn A, Kenney C, Domurath R, Hogan M, Mah T, Conley Y, Ferrell R, Weeks D, de Jong PT, van Duijn C, Haines J, Pericak-Vance M, Gorin M. A pooled case-control study of the apolipoprotein E (APOE) gene in age-related maculopathy. Ophthalmic Genet. 2002 Dec; 23(4):209-23. PMID: 12567264.
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    55. Perng GC, Mott KR, Osorio N, Yukht A, Salina S, Nguyen QH, Nesburn A, Wechsler SL. Herpes simplex virus type 1 mutants containing the KOS strain ICP34.5 gene in place of the McKrae ICP34.5 gene have McKrae-like spontaneous reactivation but non-McKrae-like virulence. J Gen Virol. 2002 Dec; 83(Pt 12):2933-42. PMID: 12466469.
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    56. Osorio Y, Wechsler SL, Nesburn A, Ghiasi H. Reduced severity of HSV-1-induced corneal scarring in IL-12-deficient mice. Virus Res. 2002 Dec; 90(1-2):317-26. PMID: 12457985.
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    57. Henderson G, Peng W, Jin L, Perng GC, Nesburn A, Wechsler SL, Jones C. Regulation of caspase 8- and caspase 9-induced apoptosis by the herpes simplex virus type 1 latency-associated transcript. J Neurovirol. 2002 Dec; 8 Suppl 2:103-11. PMID: 12491160.
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    58. Ghiasi H, Osorio Y, Nesburn A, Wechsler SL. Enhanced clearance of herpes simplex virus type 1 and reduced herpetic eye disease in STAT6 knockout mice is associated with increased IL-2. Virology. 2002 Oct 25; 302(2):286-93. PMID: 12441072.
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    59. Ghiasi H, Osorio Y, Hedvat Y, Perng GC, Nesburn A, Wechsler SL. Infection of BALB/c mice with a herpes simplex virus type 1 recombinant virus expressing IFN-gamma driven by the LAT promoter. Virology. 2002 Oct 10; 302(1):144-54. PMID: 12429523.
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    60. Ghiasi H, Osorio Y, Perng GC, Nesburn A, Wechsler SL. Overexpression of interleukin-2 by a recombinant herpes simplex virus type 1 attenuates pathogenicity and enhances antiviral immunity. J Virol. 2002 Sep; 76(18):9069-78. PMID: 12186890; PMCID: PMC136420.
    61. Perng GC, Maguen B, Jin L, Mott KR, Kurylo J, BenMohamed L, Yukht A, Osorio N, Nesburn A, Henderson G, Inman M, Jones C, Wechsler SL. A novel herpes simplex virus type 1 transcript (AL-RNA) antisense to the 5' end of the latency-associated transcript produces a protein in infected rabbits. J Virol. 2002 Aug; 76(16):8003-10. PMID: 12134005; PMCID: PMC155148.
    62. Hamdi HK, Reznik J, Castellon R, Atilano SR, Ong JM, Udar N, Tavis JH, Aoki AM, Nesburn A, Boyer DS, Small KW, Brown DJ, Kenney MC. Alu DNA polymorphism in ACE gene is protective for age-related macular degeneration. Biochem Biophys Res Commun. 2002 Jul 19; 295(3):668-72. PMID: 12099691.
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    63. BenMohamed L, Wechsler SL, Nesburn A. Lipopeptide vaccines--yesterday, today, and tomorrow. Lancet Infect Dis. 2002 Jul; 2(7):425-31. PMID: 12127354.
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    64. Samoto K, Ehtesham M, Perng GC, Hashizume K, Wechsler SL, Nesburn A, Black KL, Yu JS. A herpes simplex virus type 1 mutant with gamma 34.5 and LAT deletions effectively oncolyses human U87 glioblastomas in nude mice. Neurosurgery. 2002 Mar; 50(3):599-605; discussion 605-6. PMID: 11841729.
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    65. Perng GC, Maguen B, Jin L, Mott KR, Osorio N, Slanina SM, Yukht A, Ghiasi H, Nesburn A, Inman M, Henderson G, Jones C, Wechsler SL. A gene capable of blocking apoptosis can substitute for the herpes simplex virus type 1 latency-associated transcript gene and restore wild-type reactivation levels. J Virol. 2002 Feb; 76(3):1224-35. PMID: 11773398; PMCID: PMC135864.
    66. Ljubimov AV, Atilano SR, Garner MH, Maguen E, Nesburn A, Kenney MC. Extracellular matrix and Na+,K+-ATPase in human corneas following cataract surgery: comparison with bullous keratopathy and Fuchs' dystrophy corneas. Cornea. 2002 Jan; 21(1):74-80. PMID: 11805512.
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    67. Perng GC, Esmaili D, Slanina SM, Yukht A, Ghiasi H, Osorio N, Mott KR, Maguen B, Jin L, Nesburn A, Wechsler SL. Three herpes simplex virus type 1 latency-associated transcript mutants with distinct and asymmetric effects on virulence in mice compared with rabbits. J Virol. 2001 Oct; 75(19):9018-28. PMID: 11533165; PMCID: PMC114470.
    68. Ghiasi H, Osorio Y, Perng GC, Nesburn A, Wechsler SL. Recombinant herpes simplex virus type 1 expressing murine interleukin-4 is less virulent than wild-type virus in mice. J Virol. 2001 Oct; 75(19):9029-36. PMID: 11533166; PMCID: PMC114471.
    69. Perng GC, Slanina SM, Ghiasi H, Nesburn A, Wechsler SL. The effect of latency-associated transcript on the herpes simplex virus type 1 latency-reactivation phenotype is mouse strain-dependent. J Gen Virol. 2001 May; 82(Pt 5):1117-22. PMID: 11297686.
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    70. Samoto K, Perng GC, Ehtesham M, Liu Y, Wechsler SL, Nesburn A, Black KL, Yu JS. A herpes simplex virus type 1 mutant deleted for gamma34.5 and LAT kills glioma cells in vitro and is inhibited for in vivo reactivation. Cancer Gene Ther. 2001 Apr; 8(4):269-77. PMID: 11393279.
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    71. Inman M, Perng GC, Henderson G, Ghiasi H, Nesburn A, Wechsler SL, Jones C. Region of herpes simplex virus type 1 latency-associated transcript sufficient for wild-type spontaneous reactivation promotes cell survival in tissue culture. J Virol. 2001 Apr; 75(8):3636-46. PMID: 11264353; PMCID: PMC114855.
    72. McDonald MB, Carr JD, Frantz JM, Kozarsky AM, Maguen E, Nesburn A, Rabinowitz YS, Salz JJ, Stulting RD, Thompson KP, Waring GO. Laser in situ keratomileusis for myopia up to -11 diopters with up to -5 diopters of astigmatism with the summit autonomous LADARVision excimer laser system. Ophthalmology. 2001 Feb; 108(2):309-16. PMID: 11158804.
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    73. Ghiasi H, Hofman FM, Wallner K, Cai S, Perng G, Nesburn A, Wechsler SL. Corneal macrophage infiltrates following ocular herpes simplex virus type 1 challenge vary in BALB/c mice vaccinated with different vaccines. Vaccine. 2000 Dec 08; 19(9-10):1266-73. PMID: 11137266.
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    74. Ghiasi H, Perng GC, Nesburn A, Wechsler SL. Antibody-dependent enhancement of HSV-1 infection by anti-gK sera. Virus Res. 2000 Jul; 68(2):137-44. PMID: 10958985.
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    75. Ghiasi H, Cai S, Perng GC, Nesburn A, Wechsler SL. Both CD4+ and CD8+ T cells are involved in protection against HSV-1 induced corneal scarring. Br J Ophthalmol. 2000 Apr; 84(4):408-12. PMID: 10729300; PMCID: PMC1723442.
    76. Perng GC, Jones C, Ciacci-Zanella J, Stone M, Henderson G, Yukht A, Slanina SM, Hofman FM, Ghiasi H, Nesburn A, Wechsler SL. Virus-induced neuronal apoptosis blocked by the herpes simplex virus latency-associated transcript. Science. 2000 Feb 25; 287(5457):1500-3. PMID: 10688801.
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    77. Perng GC, Slanina SM, Yukht A, Ghiasi H, Nesburn A, Wechsler SL. The latency-associated transcript gene enhances establishment of herpes simplex virus type 1 latency in rabbits. J Virol. 2000 Feb; 74(4):1885-91. PMID: 10644361; PMCID: PMC111666.
    78. Ghiasi H, Cai S, Perng GC, Nesburn A, Wechsler SL. The role of natural killer cells in protection of mice against death and corneal scarring following ocular HSV-1 infection. Antiviral Res. 2000 Jan; 45(1):33-45. PMID: 10774588.
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    79. Ghiasi H, Cai S, Perng G, Nesburn A, Wechsler SL. Perforin pathway is essential for protection of mice against lethal ocular HSV-1 challenge but not corneal scarring. Virus Res. 1999 Dec 15; 65(2):97-101. PMID: 10581382.
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    80. Ghiasi H, Perng G, Nesburn A, Wechsler SL. Either a CD4(+)or CD8(+)T cell function is sufficient for clearance of infectious virus from trigeminal ganglia and establishment of herpes simplex virus type 1 latency in mice. Microb Pathog. 1999 Dec; 27(6):387-94. PMID: 10588911.
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    81. Perng GC, Slanina SM, Yukht A, Ghiasi H, Nesburn A, Wechsler SL. Herpes simplex virus type 1 serum neutralizing antibody titers increase during latency in rabbits latently infected with latency-associated transcript (LAT)-positive but not LAT-negative viruses. J Virol. 1999 Nov; 73(11):9669-72. PMID: 10516082; PMCID: PMC113008.
    82. McDonald MB, Deitz MR, Frantz JM, Kraff MC, Krueger RR, Salz JJ, Kraff CR, Maguen E, Matta CS, Nesburn A, Piebenga LW. Photorefractive keratectomy for low-to-moderate myopia and astigmatism with a small-beam, tracker-directed excimer laser. Ophthalmology. 1999 Aug; 106(8):1481-8; discussion 1488-9. PMID: 10442891.
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    83. Ghiasi H, Perng GC, Hofman FM, Cai S, Nesburn A, Wechsler SL, Pemg GC. Specific and nonspecific immune stimulation of MHC-II-deficient mice results in chronic HSV-1 infection of the trigeminal ganglia following ocular challenge. Virology. 1999 Jun 05; 258(2):208-16. PMID: 10366558.
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    84. Ghiasi H, Hofman FM, Cai S, Perng GC, Nesburn A, Wechsler SL. Vaccination with different HSV-1 glycoproteins induces different patterns of ocular cytokine responses following HSV-1 challenge of vaccinated mice. Vaccine. 1999 Jun 04; 17(20-21):2576-82. PMID: 10418905.
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    85. Ghiasi H, Cai S, Slanina SM, Perng GC, Nesburn A, Wechsler SL. The role of interleukin (IL)-2 and IL-4 in herpes simplex virus type 1 ocular replication and eye disease. J Infect Dis. 1999 May; 179(5):1086-93. PMID: 10191208.
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    86. Perng GC, Slanina SM, Yukht A, Drolet BS, Keleher W, Ghiasi H, Nesburn A, Wechsler SL. A herpes simplex virus type 1 latency-associated transcript mutant with increased virulence and reduced spontaneous reactivation. J Virol. 1999 Feb; 73(2):920-9. PMID: 9882292; PMCID: PMC103911.
    87. Drolet BS, Perng GC, Villosis RJ, Slanina SM, Nesburn A, Wechsler SL. Expression of the first 811 nucleotides of the herpes simplex virus type 1 latency-associated transcript (LAT) partially restores wild-type spontaneous reactivation to a LAT-null mutant. Virology. 1999 Jan 05; 253(1):96-106. PMID: 9887322.
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    88. Loutsch JM, Perng GC, Hill JM, Zheng X, Marquart ME, Block TM, Ghiasi H, Nesburn A, Wechsler SL. Identical 371-base-pair deletion mutations in the LAT genes of herpes simplex virus type 1 McKrae and 17syn+ result in different in vivo reactivation phenotypes. J Virol. 1999 Jan; 73(1):767-71. PMID: 9847385; PMCID: PMC103886.
    89. Nesburn A, Burke RL, Ghiasi H, Slanina SM, Wechsler SL. Therapeutic periocular vaccination with a subunit vaccine induces higher levels of herpes simplex virus-specific tear secretory immunoglobulin A than systemic vaccination and provides protection against recurrent spontaneous ocular shedding of virus in latently infected rabbits. Virology. 1998 Dec 05; 252(1):200-9. PMID: 9875329.
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    90. Ghiasi H, Wechsler SL, Cai S, Nesburn A, Hofman FM. The role of neutralizing antibody and T-helper subtypes in protection and pathogenesis of vaccinated mice following ocular HSV-1 challenge. Immunology. 1998 Nov; 95(3):352-9. PMID: 9824497; PMCID: PMC1364400.
    91. Nesburn A, Slanina S, Burke RL, Ghiasi H, Bahri S, Wechsler SL. Local periocular vaccination protects against eye disease more effectively than systemic vaccination following primary ocular herpes simplex virus infection in rabbits. J Virol. 1998 Oct; 72(10):7715-21. PMID: 9733807; PMCID: PMC110076.
    92. Ljubimov AV, Alba SA, Burgeson RE, Ninomiya Y, Sado Y, Sun TT, Nesburn A, Kenney MC, Maguen E. Extracellular matrix changes in human corneas after radial keratotomy. Exp Eye Res. 1998 Sep; 67(3):265-72. PMID: 9778407.
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    93. Nesburn A, Burke RL, Ghiasi H, Slanina SM, Wechsler SL. A therapeutic vaccine that reduces recurrent herpes simplex virus type 1 corneal disease. Invest Ophthalmol Vis Sci. 1998 Jun; 39(7):1163-70. PMID: 9620075.
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    94. Drolet BS, Perng GC, Cohen J, Slanina SM, Yukht A, Nesburn A, Wechsler SL. The region of the herpes simplex virus type 1 LAT gene involved in spontaneous reactivation does not encode a functional protein. Virology. 1998 Mar 01; 242(1):221-32. PMID: 9501054.
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    95. Ghiasi H, Nesburn A, Cai S, Wechsler SL. The US5 open reading frame of herpes simplex virus type 1 does encode a glycoprotein (gJ). Intervirology. 1998; 41(2-3):91-7. PMID: 9820842.
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    96. Ghiasi H, Cai S, Nesburn A, Wechsler SL. MHC-II but not MHC-I responses are required for vaccine-induced protection against ocular challenge with HSV-1. Curr Eye Res. 1997 Nov; 16(11):1152-8. PMID: 9395776.
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    97. Maguen E, Alba SA, Burgeson RE, Butkowski RJ, Michael AF, Kenney MC, Nesburn A, Ljubimov AV. Alterations of corneal extracellular matrix after multiple refractive procedures: a clinical and immunohistochemical study. Cornea. 1997 Nov; 16(6):675-82. PMID: 9395878.
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    98. Ghiasi H, Roopenian DC, Slanina S, Cai S, Nesburn A, Wechsler SL. The importance of MHC-I and MHC-II responses in vaccine efficacy against lethal herpes simplex virus type 1 challenge. Immunology. 1997 Jul; 91(3):430-5. PMID: 9301533; PMCID: PMC1364013.
    99. Kenney MC, Nesburn A, Burgeson RE, Butkowski RJ, Ljubimov AV. Abnormalities of the extracellular matrix in keratoconus corneas. Cornea. 1997 May; 16(3):345-51. PMID: 9143810.
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    100. Ghiasi H, Cai S, Slanina S, Nesburn A, Wechsler SL. Nonneutralizing antibody against the glycoprotein K of herpes simplex virus type-1 exacerbates herpes simplex virus type-1-induced corneal scarring in various virus-mouse strain combinations. Invest Ophthalmol Vis Sci. 1997 May; 38(6):1213-21. PMID: 9152241.
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    101. Maguen E, Nesburn A, Salz JJ. Bilateral photorefractive keratectomy with intentional unilateral undercorrection in an aircraft pilot. J Cataract Refract Surg. 1997 Mar; 23(2):294-6. PMID: 9113585.
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    102. Ljubimov AV, Burgeson RE, Butkowski RJ, Couchman JR, Zardi L, Ninomiya Y, Sado Y, Huang ZS, Nesburn A, Kenney MC. Basement membrane abnormalities in human eyes with diabetic retinopathy. J Histochem Cytochem. 1996 Dec; 44(12):1469-79. PMID: 8985139.
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    103. Ghiasi H, Cai S, Nesburn A, Wechsler SL. Vaccination with herpes simplex virus type 1 glycoprotein K impairs clearance of virus from the trigeminal ganglia resulting in chronic infection. Virology. 1996 Oct 01; 224(1):330-3. PMID: 8862430.
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    104. Ghiasi H, Perng GC, Cai S, Nesburn A, Wechsler SL. The UL3 open reading frame of herpes simplex virus type 1 codes for a phosphoprotein. Virus Res. 1996 Oct; 44(2):137-42. PMID: 8879142.
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    105. Ljubimov AV, Burgeson RE, Butkowski RJ, Couchman JR, Wu RR, Ninomiya Y, Sado Y, Maguen E, Nesburn A, Kenney MC. Extracellular matrix alterations in human corneas with bullous keratopathy. Invest Ophthalmol Vis Sci. 1996 May; 37(6):997-1007. PMID: 8631643.
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    106. Perng GC, Ghiasi H, Slanina SM, Nesburn A, Wechsler SL. High-dose ocular infection with a herpes simplex virus type 1 ICP34.5 deletion mutant produces no corneal disease or neurovirulence yet results in wild-type levels of spontaneous reactivation. J Virol. 1996 May; 70(5):2883-93. PMID: 8627763; PMCID: PMC190146.
    107. Perng GC, Slanina SM, Ghiasi H, Nesburn A, Wechsler SL. A 371-nucleotide region between the herpes simplex virus type 1 (HSV-1) LAT promoter and the 2-kilobase LAT is not essential for efficient spontaneous reactivation of latent HSV-1. J Virol. 1996 Mar; 70(3):2014-8. PMID: 8627728; PMCID: PMC190031.
    108. Perng GC, Ghiasi H, Slanina SM, Nesburn A, Wechsler SL. The spontaneous reactivation function of the herpes simplex virus type 1 LAT gene resides completely within the first 1.5 kilobases of the 8.3-kilobase primary transcript. J Virol. 1996 Feb; 70(2):976-84. PMID: 8551638; PMCID: PMC189902.
    109. Ghiasi H, Nesburn A, Wechsler SL. Vaccination with a cocktail of seven recombinantly expressed HSV-1 glycoproteins protects against ocular HSV-1 challenge more efficiently than vaccination with any individual glycoprotein. Vaccine. 1996 Feb; 14(2):107-12. PMID: 8852405.
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    110. Perng GC, Chokephaibulkit K, Thompson RL, Sawtell NM, Slanina SM, Ghiasi H, Nesburn A, Wechsler SL. The region of the herpes simplex virus type 1 LAT gene that is colinear with the ICP34.5 gene is not involved in spontaneous reactivation. J Virol. 1996 Jan; 70(1):282-91. PMID: 8523537; PMCID: PMC189815.
    111. Ghiasi H, Cai S, Slanina S, Nesburn A, Wechsler SL. Vaccination of mice with herpes simplex virus type 1 glycoprotein D DNA produces low levels of protection against lethal HSV-1 challenge. Antiviral Res. 1995 Oct; 28(2):147-57. PMID: 8585768.
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    112. Ghiasi H, Bahri S, Nesburn A, Wechsler SL. Protection against herpes simplex virus-induced eye disease after vaccination with seven individually expressed herpes simplex virus 1 glycoproteins. Invest Ophthalmol Vis Sci. 1995 Jun; 36(7):1352-60. PMID: 7775113.
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    113. Terrell J, Bechara SJ, Nesburn A, Waring GO, Macy J, Maloney RK. The effect of globe fixation on ablation zone centration in photorefractive keratectomy. Am J Ophthalmol. 1995 May; 119(5):612-9. PMID: 7733186.
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    114. Perng GC, Thompson RL, Sawtell NM, Taylor WE, Slanina SM, Ghiasi H, Kaiwar R, Nesburn A, Wechsler SL. An avirulent ICP34.5 deletion mutant of herpes simplex virus type 1 is capable of in vivo spontaneous reactivation. J Virol. 1995 May; 69(5):3033-41. PMID: 7707530; PMCID: PMC189003.
    115. Nesburn A, Bahri S, Salz J, Rabinowitz YS, Maguen E, Hofbauer J, Berlin M, Macy JI. Keratoconus detected by videokeratography in candidates for photorefractive keratectomy. J Refract Surg. 1995 May-Jun; 11(3):194-201. PMID: 7553090.
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    116. Ghiasi H, Wechsler SL, Kaiwar R, Nesburn A, Hofman FM. Local expression of tumor necrosis factor alpha and interleukin-2 correlates with protection against corneal scarring after ocular challenge of vaccinated mice with herpes simplex virus type 1. J Virol. 1995 Jan; 69(1):334-40. PMID: 7983727; PMCID: PMC188580.
    117. Perng GC, Dunkel EC, Geary PA, Slanina SM, Ghiasi H, Kaiwar R, Nesburn A, Wechsler SL. The latency-associated transcript gene of herpes simplex virus type 1 (HSV-1) is required for efficient in vivo spontaneous reactivation of HSV-1 from latency. J Virol. 1994 Dec; 68(12):8045-55. PMID: 7966594; PMCID: PMC237268.
    118. Maguen E, Salz JJ, Nesburn A, Warren C, Macy JI, Papaioannou T, Hofbauer J, Berlin MS. Results of excimer laser photorefractive keratectomy for the correction of myopia. Ophthalmology. 1994 Sep; 101(9):1548-56; discussion 1556-7. PMID: 8090457.
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    119. Nesburn A, Burke RL, Ghiasi H, Slanina S, Bahri S, Wechsler SL. Vaccine therapy for ocular herpes simplex virus (HSV) infection: periocular vaccination reduces spontaneous ocular HSV type 1 shedding in latently infected rabbits. J Virol. 1994 Aug; 68(8):5084-92. PMID: 8035508; PMCID: PMC236451.
    120. Maguen E, Rosner IR, Caroline P, Macy JI, Nesburn A. A retrospective study of disposable extended wear lenses in 100 patients: year 3. CLAO J. 1994 Jul; 20(3):179-82. PMID: 7955298.
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    121. Perng GC, Zwaagstra JC, Ghiasi H, Kaiwar R, Brown DJ, Nesburn A, Wechsler SL. Similarities in regulation of the HSV-1 LAT promoter in corneal and neuronal cells. Invest Ophthalmol Vis Sci. 1994 Jun; 35(7):2981-9. PMID: 8206716.
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    122. Maguen E, Nesburn A, Papaioannou T, Salz JJ, Macy JI, Warren C. Effect of nitrogen flow on recovery of vision after excimer laser photorefractive keratectomy without nitrogen flow. J Refract Corneal Surg. 1994 May-Jun; 10(3):321-6. PMID: 7522088.
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    123. Ghiasi H, Kaiwar R, Nesburn A, Slanina S, Wechsler SL. Expression of seven herpes simplex virus type 1 glycoproteins (gB, gC, gD, gE, gG, gH, and gI): comparative protection against lethal challenge in mice. J Virol. 1994 Apr; 68(4):2118-26. PMID: 8138996; PMCID: PMC236686.
    124. Ghiasi H, Slanina S, Nesburn A, Wechsler SL. Characterization of baculovirus-expressed herpes simplex virus type 1 glycoprotein K. J Virol. 1994 Apr; 68(4):2347-54. PMID: 8139020; PMCID: PMC236711.
    125. Perng GC, Ghiasi H, Kaiwar R, Nesburn A, Wechsler SL. An improved method for cloning portions of the repeat regions of herpes simplex virus type 1. J Virol Methods. 1994 Feb; 46(2):111-6. PMID: 8188808.
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    126. Ghiasi H, Kaiwar R, Slanina S, Nesburn A, Wechsler SL. Expression and characterization of baculovirus expressed herpes simplex virus type 1 glycoprotein L. Arch Virol. 1994; 138(3-4):199-212. PMID: 7998829.
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    127. Salz JJ, Maguen E, Nesburn A, Warren C, Macy JI, Hofbauer JD, Papaioannou T, Berlin M. A two-year experience with excimer laser photorefractive keratectomy for myopia. Ophthalmology. 1993 Jun; 100(6):873-82. PMID: 8510900.
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    128. Rabinowitz YS, Nesburn A, McDonnell PJ. Videokeratography of the fellow eye in unilateral keratoconus. Ophthalmology. 1993 Feb; 100(2):181-6. PMID: 8437824.
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    129. Maguen E, Rosner I, Caroline P, Macy JI, Nesburn A. A retrospective study of disposable extended wear lenses in 100 patients: year 2. CLAO J. 1992 Oct; 18(4):229-31. PMID: 1424056.
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    130. Ghiasi H, Kaiwar R, Nesburn A, Wechsler SL. Baculovirus-expressed glycoprotein G of herpes simplex virus type 1 partially protects vaccinated mice against lethal HSV-1 challenge. Virology. 1992 Sep; 190(1):233-9. PMID: 1529531.
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    131. Salz JJ, Maguen E, Macy JI, Papaioannou T, Hofbauer J, Nesburn A. One-year results of excimer laser photorefractive keratectomy for myopia. Refract Corneal Surg. 1992 Jul-Aug; 8(4):269-73. PMID: 1390405.
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    132. Maguen E, Caroline P, Rosner IR, Macy JI, Nesburn A. The use of the SoftPerm lens for the correction of irregular astigmatism. CLAO J. 1992 Jul; 18(3):173-6. PMID: 1499124.
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    133. Ghiasi H, Kaiwar R, Nesburn A, Wechsler SL. Baculovirus expressed herpes simplex virus type 1 glycoprotein C protects mice from lethal HSV-1 infection. Antiviral Res. 1992 Jun; 18(3-4):291-302. PMID: 1416910.
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    134. Ghiasi H, Kaiwar R, Nesburn A, Slanina S, Wechsler SL. Baculovirus-expressed glycoprotein E (gE) of herpes simplex virus type-1 (HSV-1) protects mice against lethal intraperitoneal and lethal ocular HSV-1 challenge. Virology. 1992 Jun; 188(2):469-76. PMID: 1585630.
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    135. Ghiasi H, Kaiwar R, Nesburn A, Wechsler SL. Expression of herpes simplex virus type 1 glycoprotein I in baculovirus: preliminary biochemical characterization and protection studies. J Virol. 1992 Apr; 66(4):2505-9. PMID: 1548774; PMCID: PMC289047.
    136. Maguen E, Salz JJ, Nesburn A. Pseudomonas corneal ulcer associated with rigid, gas-permeable, daily-wear lenses in a patient infected with human immunodeficiency virus. Am J Ophthalmol. 1992 Mar 15; 113(3):336-7. PMID: 1543232.
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    137. Ghiasi H, Kaiwar R, Nesburn A, Wechsler SL. Baculovirus-expressed glycoprotein H of herpes simplex virus type 1 (HSV-1) induces neutralizing antibody and delayed type hypersensitivity responses, but does not protect immunized mice against lethal HSV-1 challenge. J Gen Virol. 1992 Mar; 73 ( Pt 3):719-22. PMID: 1312127.
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    138. Ghiasi H, Kaiwar R, Nesburn A, Wechsler SL. Expression of herpes simplex virus type 1 glycoprotein B in insect cells. Initial analysis of its biochemical and immunological properties. Virus Res. 1992 Jan; 22(1):25-39. PMID: 1311136.
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    139. Ghiasi H, Nesburn A, Wechsler SL. Cell surface expression of herpes simplex virus type 1 glycoprotein H in recombinant baculovirus-infected cells. Virology. 1991 Nov; 185(1):187-94. PMID: 1656584.
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    140. Maguen E, Tsai JC, Martinez M, Rosner I, Cot PC, Macy JI, Nesburn A. A retrospective study of disposable extended-wear lenses in 100 patients. Ophthalmology. 1991 Nov; 98(11):1685-9. PMID: 1800930.
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    141. Zwaagstra JC, Ghiasi H, Nesburn A, Wechsler SL. Identification of a major regulatory sequence in the latency associated transcript (LAT) promoter of herpes simplex virus type 1 (HSV-1). Virology. 1991 May; 182(1):287-97. PMID: 1850907.
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    142. Ghiasi H, Nesburn A, Kaiwar R, Wechsler SL. Immunoselection of recombinant baculoviruses expressing high levels of biologically active herpes simplex virus type 1 glycoprotein D. Arch Virol. 1991; 121(1-4):163-78. PMID: 1662037.
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    143. Maguen E, Martinez M, Rosner IR, Caroline P, Macy J, Nesburn A. The use of Saturn II lenses in keratoconus. CLAO J. 1991 Jan; 17(1):41-3. PMID: 2007284.
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    144. Zwaagstra JC, Ghiasi H, Slanina SM, Nesburn A, Wheatley SC, Lillycrop K, Wood J, Latchman DS, Patel K, Wechsler SL. Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript. J Virol. 1990 Oct; 64(10):5019-28. PMID: 2168984; PMCID: PMC247993.
    145. Nesburn A, Ghiasi H, Wechsler SL. Ocular safety and efficacy of an HSV-1 gD vaccine during primary and latent infection. Invest Ophthalmol Vis Sci. 1990 Aug; 31(8):1497-502. PMID: 2167298.
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    146. Zwaagstra J, Ghiasi H, Nesburn A, Wechsler SL. In vitro promoter activity associated with the latency-associated transcript gene of herpes simplex virus type 1. J Gen Virol. 1989 Aug; 70 ( Pt 8):2163-9. PMID: 2549185.
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    147. Maguen E, Martinez M, Grundfest W, Papaioannou T, Berlin M, Nesburn A. Excimer laser ablation of the human lens at 308 nm with a fiber delivery system. J Cataract Refract Surg. 1989 Jul; 15(4):409-14. PMID: 2778687.
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    148. Wechsler SL, Nesburn A, Zwaagstra J, Ghiasi H. Sequence of the latency-related gene of herpes simplex virus type 1. Virology. 1989 Jan; 168(1):168-72. PMID: 2535901.
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    149. Wechsler SL, Nesburn A, Watson R, Slanina S, Ghiasi H. Fine mapping of the major latency-related RNA of herpes simplex virus type 1 in humans. J Gen Virol. 1988 Dec; 69 ( Pt 12):3101-6. PMID: 2848928.
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    150. Wechsler SL, Nesburn A, Watson R, Slanina SM, Ghiasi H. Fine mapping of the latency-related gene of herpes simplex virus type 1: alternative splicing produces distinct latency-related RNAs containing open reading frames. J Virol. 1988 Nov; 62(11):4051-8. PMID: 2845123; PMCID: PMC253835.
    151. Critchfield JW, Calandra AJ, Nesburn A, Kenney MC. Keratoconus: I. Biochemical studies. Exp Eye Res. 1988 Jun; 46(6):953-63. PMID: 3197764.
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    152. Rock DL, Nesburn A, Ghiasi H, Ong J, Lewis TL, Lokensgard JR, Wechsler SL. Detection of latency-related viral RNAs in trigeminal ganglia of rabbits latently infected with herpes simplex virus type 1. J Virol. 1987 Dec; 61(12):3820-6. PMID: 2824816; PMCID: PMC255998.
    153. Maguen E, Nesburn A. Extended-wear cosmetic lenses. Int Ophthalmol Clin. 1986; 26(1):149-60. PMID: 3456341.
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    154. Maguen E, Isitt J, Pinhas S, Nesburn A. Extraction of soluble proteins reduces rejection in rabbit porcine corneal xenografts. Cornea. 1986; 5(3):163-6. PMID: 2980834.
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    155. Willey DE, Smith MD, Nesburn A, Trousdale MD. Sequential analysis of antibody responses in serum, aqueous humor and tear film during latent and induced recurrent HSV infections. Curr Eye Res. 1985 Dec; 4(12):1235-40. PMID: 3878766.
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    156. Maguen E, Nesburn A, Jackman N, Macy JI. Broken semiflexible intraocular lens implant. Am J Ophthalmol. 1985 Feb 15; 99(2):170-2. PMID: 3970120.
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    157. Nesburn A, Lowe GH, Lepoff NJ, Maguen E. Effect of topical trifluridine on Thygeson's superficial punctate keratitis. Ophthalmology. 1984 Oct; 91(10):1188-92. PMID: 6440070.
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    158. Maguen E, Nesburn A, Verity SM, Rosner IR. Myopic extended wear contact lenses in 100 patients: a retrospective study. CLAO J. 1984 Oct-Dec; 10(4):335-40. PMID: 6595078.
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    159. Trousdale MD, Nesburn A, Willey DE, Taaid H. Efficacy of BW759 (9-[[2-hydroxy-1(hydroxymethyl)ethoxy]methyl]guanine) against herpes simplex virus type 1 keratitis in rabbits. Curr Eye Res. 1984 Aug; 3(8):1007-15. PMID: 6333319.
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    160. Willey DE, Trousdale MD, Nesburn A. Reactivation of murine latent HSV infection by epinephrine iontophoresis. Invest Ophthalmol Vis Sci. 1984 Aug; 25(8):945-50. PMID: 6086546.
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    161. Trousdale MD, Nesburn A. Human interferon alpha A or alpha D and trifluridine treatment for herpetic keratitis in rabbits. Invest Ophthalmol Vis Sci. 1984 Apr; 25(4):480-3. PMID: 6423563.
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    162. Trousdale MD, Gordon YJ, Peters AC, Gropen TI, Nelson E, Nesburn A. Evaluation of lithium as an inhibitory agent of herpes simplex virus in cell cultures and during reactivation of latent infection in rabbits. Antimicrob Agents Chemother. 1984 Apr; 25(4):522-3. PMID: 6329084; PMCID: PMC185570.
    163. Maguen E, Nesburn A, Macy JI. Combined use of sodium hyaluronate and tissue adhesive in penetrating keratoplasty of corneal perforations. Ophthalmic Surg. 1984 Jan; 15(1):55-7. PMID: 6366683.
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    164. Willey DE, Maguen E, Pinhas S, Verity SM, Nesburn A. Antibody response following implantation of xenogenic lenticules. Cornea. 1984; 3(1):33-6. PMID: 6536423.
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    165. Maguen E, Pinhas S, Verity SM, Nesburn A. Keratophakia with lyophilized cornea lathed at room temperature: new techniques and experimental surgical results. Ophthalmic Surg. 1983 Sep; 14(9):759-62. PMID: 6358989.
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    166. Nesburn A, Mandelbaum S, Willey DE, Trousdale MD, Maguen E, Ward DE. A specular microscopic viewing system for donor corneas. Ophthalmology. 1983 Jun; 90(6):686-91. PMID: 6350972.
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    167. Trousdale MD, Nesburn A, Su TL, Lopez C, Watanabe KA, Fox JJ. Activity of 1-(2'-fluoro-2'-deoxy-beta-D-arabinofuranosyl)thymine against herpes simplex virus in cell cultures and rabbit eyes. Antimicrob Agents Chemother. 1983 Jun; 23(6):808-13. PMID: 6311085; PMCID: PMC184970.
    168. Nesburn A, Willey DE, Trousdale MD. Effect of intensive acyclovir therapy during artificial reactivation of latent herpes simplex virus. Proc Soc Exp Biol Med. 1983 Mar; 172(3):316-23. PMID: 6302707.
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    169. Maguen E, Espinosa G, Rosner IR, Nesburn A. Long-term wear of Polycon contact lenses in keratoconus. CLAO J. 1983 Jan-Mar; 9(1):57-9. PMID: 6839436.
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    170. Maguen E, Azen SP, Pinhas S, Villaseñor RA, Nesburn A. Evaluation of sources of variation on the accuracy and reproducibility of microkeratome sections with the modified artificial anterior chamber. Ophthalmic Surg. 1982 Mar; 13(3):217-20. PMID: 7045759.
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    171. Maguen E, Nesburn A. A new technique for lathing lyophilized cornea for refractive keratoplasty. Arch Ophthalmol. 1982 Jan; 100(1):119-21. PMID: 7034703.
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    172. Villasenor RA, Jester JV, Salz J, Steel D, Maguen E, Nesburn A, Krasnow M, Smith RE. Preliminary study of keratomileusis in primates (Macaca speciosa). Ophthalmology. 1981 Aug; 88(8):724-8. PMID: 7322494.
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    173. Salz J, Lee JS, Jester JV, Steel D, Villasenor RA, Nesburn A, Smith RE. Radial keratotomy in fresh human cadaver eyes. Ophthalmology. 1981 Aug; 88(8):742-6. PMID: 7322496.
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    174. Trousdale MD, Nesburn A, Miller CA. Assessment of acyclovir on acute ocular infection induced by drug-resistant strains of HSV-1. Invest Ophthalmol Vis Sci. 1981 Feb; 20(2):230-5. PMID: 6257622.
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    175. Nesburn A, Maguen E. Cosmetic lenses. Int Ophthalmol Clin. 1981; 21(2):209-19. PMID: 6165696.
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    176. Trousdale MD, Dunkel EC, Nesburn A. Effect of acyclovir on acute and latent herpes simplex virus infections in the rabbit. Invest Ophthalmol Vis Sci. 1980 Nov; 19(11):1336-41. PMID: 7429768.
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    177. Maguen E, Villaseñor RA, Ward DE, Nesburn A. A modified artificial anterior chamber for use in refractive keratoplasty. Am J Ophthalmol. 1980 May; 89(5):742-4. PMID: 6990768.
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    178. Trousdale MD, Dunkel EC, Nesburn A. Effect of flurbiprofen on herpes simplex keratitis in rabbits. Invest Ophthalmol Vis Sci. 1980 Mar; 19(3):267-70. PMID: 7358477.
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    179. Nesburn A, Green MT, Radnoti M, Walker B. Reliable in vivo model for latent herpes simplex virus reactivation with peripheral virus shedding. Infect Immun. 1977 Mar; 15(3):772-5. PMID: 192675; PMCID: PMC421438.
    180. Nesburn A, Dickinson R, Radnoti M. The effect of trigeminal nerve and ganglion manipulation on recurrence of ocular herpes simplex in rabbits. Invest Ophthalmol. 1976 Sep; 15(9):726-31. PMID: 183501.
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    181. Nesburn A, Dickinson R, Radnoti M, Green MJ. Experimental reactivation of ocular herpes simplex in rabbits. Surv Ophthalmol. 1976 Sep-Oct; 21(2):185-90. PMID: 185740.
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    182. Nesburn A. Recurrence in ocular herpes simplex infection. Int Ophthalmol Clin. 1975; 15(4):101-10. PMID: 178617.
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    183. Nesburn A, Cook ML, Stevens JG. Latent herpes simplex virus. Isolation from rabbit trigeminal ganglia between episodes of recurrent ocular infection. Arch Ophthalmol. 1972 Oct; 88(4):412-7. PMID: 4342439.
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    184. Stevens JG, Nesburn A, Cook ML. Latent herpes simplex virus from trigeminal ganglia of rabbits with recurrent eye infection. Nat New Biol. 1972 Feb 16; 235(59):216-7. PMID: 4334930.
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    185. Nesburn A, Ziniti PJ. Long-term poly I:C in experimental chronic ocular herpes simplex infection. Am J Ophthalmol. 1971 Oct; 72(4):821-6. PMID: 4329367.
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    186. Nesburn A. Isolation and characterization of a herpes-like virus from New Zealand albino rabbit kidney cell cultures: a probable reisolation of virus 3 of Rivers. J Virol. 1969 Jan; 3(1):59-69. PMID: 4977241; PMCID: PMC375730.
    187. Pavan-Langston D, Nesburn A. The chronology of primary herpes simplex infection of the eye and adnexal glands. Arch Ophthalmol. 1968 Aug; 80(2):258-64. PMID: 4298542.
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    188. Brown DC, Nesburn A, Nauheim JS, Pavan-Langston D, Kaufman HE. Recurrent herpes simplex conjunctivitis. Arch Ophthalmol. 1968 Jun; 79(6):733-5. PMID: 5652264.
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    189. Nesburn A, Elliott JH, Leibowitz HM. Spontaneous reactivation of experimental herpes simplex keratitis in rabbits. Arch Ophthalmol. 1967 Oct; 78(4):523-9. PMID: 4167294.
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