Lbachir Benmohamed

Title(s)Professor, Ophthalmology
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-8937
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    Collapse Research 
    Collapse Research Activities and Funding
    Developing a Multi-epitope Pan-Coronavirus Vaccine
    NIH R01AI158060Aug 7, 2020 - Jul 31, 2025
    Role: Principal Investigator
    A Novel Prime/Pull Therapeutic Vaccine Strategy to Prevent Recurrent Genital Herpes
    NIH R01AI150091Jan 10, 2020 - Dec 31, 2024
    Role: Principal Investigator
    Mucosal Chemokines and CD8+ T Cell Immunity to Genital Herpes
    NIH R01AI143348Aug 15, 2019 - Jul 31, 2023
    Role: Principal Investigator
    PROTECTIVE IMMUNITY AGAINST RECURRENT OCULAR HERPES INDUCED WITH SELF-ASSEMBLING PROTEIN NANOPARTICLES
    NIH R21AI147499Jun 6, 2019 - May 31, 2021
    Role: Principal Investigator
    Impact of Immune Checkpoints Blockade on HSV-1 Neuro-Pathogenesis
    NIH R21AI143326Jan 14, 2019 - Dec 31, 2020
    Role: Principal Investigator
    A NOVEL SELF-ASSEMBLING PROTEIN NANOPARTICLES-BASED GENITAL HERPES VACCINE
    NIH R41AI138764Apr 1, 2018 - Mar 31, 2020
    Role: Principal Investigator
    Mechanisms of CD8+ T Cell Dynamics in Recurrent Ocular Herpetic Disease
    NIH R01EY026103Aug 1, 2016 - Jul 31, 2021
    Role: Principal Investigator
    LAT-HVEM Interactions Effect HSV-1 Latency/Reactivation
    NIH R21AI110902Jul 1, 2015 - Jun 30, 2018
    Role: Principal Investigator
    Blockade of T-cell Co-Inhibitory Pathways & Immunotherapy to Prevent Ocular Herpe
    NIH R01EY024618Sep 3, 2014 - Aug 31, 2018
    Role: Principal Investigator
    Therapeutic Ocular HSV Vaccine in HLA Transgenic Rabbits
    NIH R01EY019896Sep 1, 2010 - Mar 31, 2021
    Role: Principal Investigator
    Ocular Mucosal Immunity Induced by HSV-1 Lipopeptide
    NIH R01EY014900Sep 30, 2003 - Mar 31, 2016
    Role: Principal Investigator
    Interaction of HSV-1 LAT Gene &Dendritic Cells Function
    NIH R03EY014017Apr 1, 2002 - Mar 31, 2005
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dynamics of Spike-Specific Neutralizing Antibodies Across Five-Year Emerging SARS-CoV-2 Variants of Concern Reveal Conserved Epitopes that Protect Against Severe COVID-19. bioRxiv. 2024 Sep 25. Zayou L, Prakash S, Vahed H, Dhanushkodi NR, Quadiri A, Belmouden A, Lemkhente Z, Chentoufi A, Gil D, Ulmer JB, BenMohamed L. PMID: 39386567; PMCID: PMC11463540.
      View in: PubMed   Mentions:
    2. Therapeutic prime/pull vaccination of HSV-2-infected guinea pigs with the ribonucleotide reductase 2 (RR2) protein and CXCL11 chemokine boosts antiviral local tissue-resident and effector memory CD4+ and CD8+ T cells and protects against recurrent genital herpes. J Virol. 2024 May 14; 98(5):e0159623. Quadiri A, Prakash S, Dhanushkodi NR, Singer M, Zayou L, Shaik AM, Sun M, Suzer B, Lau LSL, Chilukurri A, Vahed H, Schaefer H, BenMohamed L. PMID: 38587378; PMCID: PMC11092353.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    3. High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4+ and CD8+ memory T cells are associated with protection from symptomatic and fatal SARS-CoV-2 infections in unvaccinated COVID-19 patients. Front Immunol. 2024; 15:1343716. Coulon PG, Prakash S, Dhanushkodi NR, Srivastava R, Zayou L, Tifrea DF, Edwards RA, Figueroa CJ, Schubl SD, Hsieh L, Nesburn AB, Kuppermann BD, Bahraoui E, Vahed H, Gil D, Jones TM, Ulmer JB, BenMohamed L. PMID: 38605956; PMCID: PMC11007208.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model. bioRxiv. 2024 Feb 15. Prakash S, Dhanushkodi NR, Singer M, Quadiri A, Zayou L, Vahed H, Coulon PG, Ibraim IC, Tafoya C, Hitchcock L, Landucci G, Forthal DN, El Babsiri A, Tifrea DF, Figueroa CJ, Nesburn AB, Kuppermann BD, Gil D, Jones TM, Ulmer JB, BenMohamed L. PMID: 38405942; PMCID: PMC10888826.
      View in: PubMed   Mentions:
    5. Antiviral and Anti-Inflammatory Therapeutic Effect of RAGE-Ig Protein against Multiple SARS-CoV-2 Variants of Concern Demonstrated in K18-hACE2 Mouse and Syrian Golden Hamster Models. J Immunol. 2024 Feb 15; 212(4):576-585. Dhanushkodi NR, Prakash S, Quadiri A, Zayou L, Srivastava R, Shaik AM, Suzer B, Ibraim IC, Landucci G, Tifrea DF, Singer M, Jamal L, Edwards RA, Vahed H, Brown L, BenMohamed L. PMID: 38180084.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. Cross-protection induced by highly conserved human B, CD4+, and CD8+ T-cell epitopes-based vaccine against severe infection, disease, and death caused by multiple SARS-CoV-2 variants of concern. Front Immunol. 2024; 15:1328905. Prakash S, Dhanushkodi NR, Zayou L, Ibraim IC, Quadiri A, Coulon PG, Tifrea DF, Suzer B, Shaik AM, Chilukuri A, Edwards RA, Singer M, Vahed H, Nesburn AB, Kuppermann BD, Ulmer JB, Gil D, Jones TM, BenMohamed L. PMID: 38318166; PMCID: PMC10839970.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    7. A multi-epitope/CXCL11 prime/pull coronavirus mucosal vaccine boosts the frequency and the function of lung-resident memory CD4+ and CD8+ T cells and enhanced protection against COVID-19-like symptoms and death caused by SARS-CoV-2 infection. J Virol. 2023 Dec 21; 97(12):e0109623. Zayou L, Prakash S, Dhanushkodi NR, Quadiri A, Ibraim IC, Singer M, Salem A, Shaik AM, Suzer B, Chilukuri A, Tran J, Nguyen PC, Sun M, Hormi-Carver KK, Belmouden A, Vahed H, Gil D, Ulmer JB, BenMohamed L. PMID: 38038432; PMCID: PMC10734477.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    8. Therapeutic Prime/Pull Vaccination of HSV-2 Infected Guinea Pigs with the Ribonucleotide Reductase 2 (RR2) Protein and CXCL11 Chemokine Boosts Antiviral Local Tissue-Resident and Effector Memory CD4+ and CD8+ T Cells and Protects Against Recurrent Genital Herpes. bioRxiv. 2023 Aug 09. Quadiri A, Prakash S, Dhanushkodi NR, Singer M, Zayou L, Shaik AM, Sun M, Suzer B, Lau L, Chilukurri A, Vahed H, Schaefer H, BenMohamed L. PMID: 37609157; PMCID: PMC10441333.
      View in: PubMed   Mentions:
    9. Mucosal CCL28 Chemokine Improves Protection against Genital Herpes through Mobilization of Antiviral Effector Memory CCR10+CD44+ CD62L-CD8+ T Cells and Memory CCR10+B220+CD27+ B Cells into the Infected Vaginal Mucosa. J Immunol. 2023 07 01; 211(1):118-129. Dhanushkodi NR, Prakash S, Quadiri A, Zayou L, Srivastava R, Tran J, Dang V, Shaik AM, Chilukurri A, Suzer B, Vera P, Sun M, Nguyen P, Lee A, Salem A, Loi J, Singer M, Nakayama T, Vahed H, Nesburn AB, BenMohamed L. PMID: 37222480; PMCID: PMC10330291.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    10. Cross-Protection Induced by Highly Conserved Human B, CD4+, and CD8+ T Cell Epitopes-Based Coronavirus Vaccine Against Severe Infection, Disease, and Death Caused by Multiple SARS-CoV-2 Variants of Concern. bioRxiv. 2023 May 24. Prakash S, Dhanushkodi NR, Zayou L, Ibraim IC, Quadiri A, Coulon PG, Tifrea DF, Suzler B, Amin M, Chilukuri A, Edwards RA, Vahed H, Nesburn AB, Kuppermann BD, Ulmer JB, Gil D, Jones TM, BenMohamed L. PMID: 37292861; PMCID: PMC10245830.
      View in: PubMed   Mentions:
    11. High Frequencies of Antiviral Effector Memory TEM Cells and Memory B Cells Mobilized into Herpes Infected Vaginal Mucosa Associated With Protection Against Genital Herpes. bioRxiv. 2023 May 24. Dhanushkodi NR, Prakash S, Quadiri A, Zayou L, Singer M, Takashi N, Vahed H, BenMohamed L. PMID: 37292784; PMCID: PMC10245907.
      View in: PubMed   Mentions:
    12. High Frequencies of Phenotypically and Functionally Senescent and Exhausted CD56+CD57+PD-1+ Natural Killer Cells, SARS-CoV-2-Specific Memory CD4+ and CD8+ T cells Associated with Severe Disease in Unvaccinated COVID-19 Patients. bioRxiv. 2022 Jul 27. Srivastava R, Dhanushkodi N, Prakash S, Coulon PG, Vahed H, Zayou L, Quadiri A, BenMohamed L. PMID: 35923316; PMCID: PMC9347283.
      View in: PubMed   Mentions:
    13. SARS-CoV-2 Envelope (E) Protein Binds and Activates TLR2 Pathway: A Novel Molecular Target for COVID-19 Interventions. Viruses. 2022 05 08; 14(5). Planès R, Bert JB, Tairi S, BenMohamed L, Bahraoui E. PMID: 35632741; PMCID: PMC9146335.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    14. Combinatorial Herpes Simplex Vaccine Strategies: From Bedside to Bench and Back. Front Immunol. 2022; 13:849515. Chentoufi AA, Dhanushkodi NR, Srivastava R, Prakash S, Coulon PA, Zayou L, Vahed H, Chentoufi HA, Hormi-Carver KK, BenMohamed L. PMID: 35547736; PMCID: PMC9082490.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    15. Antiviral CD19+CD27+ Memory B Cells Are Associated with Protection from Recurrent Asymptomatic Ocular Herpesvirus Infection. J Virol. 2022 03 09; 96(5):e0205721. Dhanushkodi NR, Prakash S, Srivastava R, Coulon PA, Arellano D, Kapadia RV, Fahim R, Suzer B, Jamal L, Vahed H, BenMohamed L. PMID: 34985998; PMCID: PMC8906405.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    16. Healing of Ocular Herpetic Disease Following Treatment With an Engineered FGF-1 Is Associated With Increased Corneal Anti-Inflammatory M2 Macrophages. Front Immunol. 2021; 12:673763. Dhanushkodi NR, Srivastava R, Coulon PA, Prakash S, Roy S, Bagnol D, David ED, BenMohamed L. PMID: 34054858; PMCID: PMC8158292.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    17. Genome-Wide B Cell, CD4+, and CD8+ T Cell Epitopes That Are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Targets for Preemptive Pan-Coronavirus Vaccines. J Immunol. 2021 06 01; 206(11):2566-2582. Prakash S, Srivastava R, Coulon PG, Dhanushkodi NR, Chentoufi AA, Tifrea DF, Edwards RA, Figueroa CJ, Schubl SD, Hsieh L, Buchmeier MJ, Bouziane M, Nesburn AB, Kuppermann BD, BenMohamed L. PMID: 33911008; PMCID: PMC8722450.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    18. Genome-Wide Asymptomatic B-Cell, CD4 + and CD8 + T-Cell Epitopes, that are Highly Conserved Between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Immune Targets for Pre-Emptive Pan-Coronavirus Vaccines. bioRxiv. 2020 Sep 28. Prakash S, Srivastava R, Coulon PG, Dhanushkodi NR, Chentoufi AA, Tifrea DF, Edwards RA, Figueroa CJ, Schubl SD, Hsieh L, Buchmeier MJ, Bouziane M, Nesburn AB, Kuppermann BD, BenMohamed L. PMID: 33024971; PMCID: PMC7536874.
      View in: PubMed   Mentions:
    19. Unique molecular signatures of antiviral memory CD8+ T cells associated with asymptomatic recurrent ocular herpes. Sci Rep. 2020 08 14; 10(1):13843. Prakash S, Roy S, Srivastava R, Coulon PG, Dhanushkodi NR, Vahed H, Jankeel A, Geertsema R, Amezquita C, Nguyen L, Messaoudi I, Burkhardt AM, BenMohamed L. PMID: 32796943; PMCID: PMC7427992.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    20. Upregulation of Multiple CD8+ T Cell Exhaustion Pathways Is Associated with Recurrent Ocular Herpes Simplex Virus Type 1 Infection. J Immunol. 2020 07 15; 205(2):454-468. Coulon PG, Roy S, Prakash S, Srivastava R, Dhanushkodi N, Salazar S, Amezquita C, Nguyen L, Vahed H, Nguyen AM, Warsi WR, Ye C, Carlos-Cruz EA, Mai UT, BenMohamed L. PMID: 32540992; PMCID: PMC7343593.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    21. High Frequency of Gamma Interferon-Producing PLZFloRORγtlo Invariant Natural Killer 1 Cells Infiltrating Herpes Simplex Virus 1-Infected Corneas Is Associated with Asymptomatic Ocular Herpesvirus Infection. J Virol. 2020 04 16; 94(9). Dhanushkodi NR, Srivastava R, Prakash S, Roy S, Coulon PA, Vahed H, Nguyen AM, Salazar S, Nguyen L, Amezquita C, Ye C, Nguyen V, BenMohamed L. PMID: 32102882; PMCID: PMC7163123.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    22. Human Epitopes Identified from Herpes Simplex Virus Tegument Protein VP11/12 (UL46) Recall Multifunctional Effector Memory CD4+ TEM Cells in Asymptomatic Individuals and Protect from Ocular Herpes Infection and Disease in "Humanized" HLA-DR Transgenic Mice. J Virol. 2020 03 17; 94(7). Srivastava R, Coulon PA, Prakash S, Dhanushkodi NR, Roy S, Nguyen AM, Alomari NI, Mai UT, Amezquita C, Ye C, Maillère B, BenMohamed L. PMID: 31915285; PMCID: PMC7081904.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    23. Trimeric heptad repeat synthetic peptides HR1 and HR2 efficiently inhibit HIV-1 entry. Biosci Rep. 2019 09 30; 39(9). Mzoughi O, Teixido M, Planès R, Serrero M, Hamimed I, Zurita E, Moreno M, Granados G, Lakhdar-Ghazal F, BenMohamed L, Giralt E, Bahraoui E. PMID: 31477581; PMCID: PMC6757187.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    24. Blockade of PD-1 and LAG-3 Immune Checkpoints Combined with Vaccination Restores the Function of Antiviral Tissue-Resident CD8+ TRM Cells and Reduces Ocular Herpes Simplex Infection and Disease in HLA Transgenic Rabbits. J Virol. 2019 09 15; 93(18). Roy S, Coulon PG, Prakash S, Srivastava R, Geertsema R, Dhanushkodi N, Lam C, Nguyen V, Gorospe E, Nguyen AM, Salazar S, Alomari NI, Warsi WR, BenMohamed L. PMID: 31217250; PMCID: PMC6714801.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    25. NLRP3, NLRP12, and IFI16 Inflammasomes Induction and Caspase-1 Activation Triggered by Virulent HSV-1 Strains Are Associated With Severe Corneal Inflammatory Herpetic Disease. Front Immunol. 2019; 10:1631. Coulon PG, Dhanushkodi N, Prakash S, Srivastava R, Roy S, Alomari NI, Nguyen AM, Warsi WR, Ye C, Carlos-Cruz EA, Mai UT, Cruel AC, Ekmekciyan KM, Pearlman E, BenMohamed L. PMID: 31367214; PMCID: PMC6644090.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    26. Author Correction: The wide utility of rabbits as models of human diseases. Exp Mol Med. 2019 Jul 04; 51(7):1. Esteves PJ, Abrantes J, Baldauf HM, BenMohamed L, Chen Y, Christensen N, González-Gallego J, Giacani L, Hu J, Kaplan G, Keppler OT, Knight KL, Kong XP, Lanning DK, Le Pendu J, de Matos AL, Liu J, Liu S, Lopes AM, Lu S, Lukehart S, Manabe YC, Neves F, McFadden G, Pan R, Peng X, de Sousa-Pereira P, Pinheiro A, Rahman M, Ruvoën-Clouet N, Subbian S, Tuñón MJ, van der Loo W, Vaine M, Via LE, Wang S, Mage R. PMID: 31270317; PMCID: PMC6802666.
      View in: PubMed   Mentions: 7     Fields:    
    27. Therapeutic Mucosal Vaccination of Herpes Simplex Virus 2-Infected Guinea Pigs with Ribonucleotide Reductase 2 (RR2) Protein Boosts Antiviral Neutralizing Antibodies and Local Tissue-Resident CD4+ and CD8+ TRM Cells Associated with Protection against Recurrent Genital Herpes. J Virol. 2019 05 01; 93(9). Srivastava R, Roy S, Coulon PG, Vahed H, Prakash S, Dhanushkodi N, Kim GJ, Fouladi MA, Campo J, Teng AA, Liang X, Schaefer H, BenMohamed L. PMID: 30787156; PMCID: PMC6475797.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    28. Unique Type I Interferon, Expansion/Survival Cytokines, and JAK/STAT Gene Signatures of Multifunctional Herpes Simplex Virus-Specific Effector Memory CD8+ TEM Cells Are Associated with Asymptomatic Herpes in Humans. J Virol. 2019 02 15; 93(4). Vahed H, Agrawal A, Srivastava R, Prakash S, Coulon PA, Roy S, BenMohamed L. PMID: 30487281; PMCID: PMC6364001.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsPHPublic Health
    29. Blockade of LAG-3 Immune Checkpoint Combined With Therapeutic Vaccination Restore the Function of Tissue-Resident Anti-viral CD8+ T Cells and Protect Against Recurrent Ocular Herpes Simplex Infection and Disease. Front Immunol. 2018; 9:2922. Roy S, Coulon PG, Srivastava R, Vahed H, Kim GJ, Walia SS, Yamada T, Fouladi MA, Ly VT, BenMohamed L. PMID: 30619285; PMCID: PMC6304367.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    30. HIV-1 Envelope Glycoproteins Induce the Production of TNF-α and IL-10 in Human Monocytes by Activating Calcium Pathway. Sci Rep. 2018 11 21; 8(1):17215. Planès R, Serrero M, Leghmari K, BenMohamed L, Bahraoui E. PMID: 30464243; PMCID: PMC6249280.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    31. Phenotypic and Functional Signatures of Herpes Simplex Virus-Specific Effector Memory CD73+CD45RAhighCCR7lowCD8+ TEMRA and CD73+CD45RAlowCCR7lowCD8+ TEM Cells Are Associated with Asymptomatic Ocular Herpes. J Immunol. 2018 10 15; 201(8):2315-2330. Srivastava R, Coulon PG, Roy S, Chilukuri S, Garg S, BenMohamed L. PMID: 30201808; PMCID: PMC6195422.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    32. Human Asymptomatic Epitope Peptide/CXCL10-Based Prime/Pull Vaccine Induces Herpes Simplex Virus-Specific Gamma Interferon-Positive CD107+ CD8+ T Cells That Infiltrate the Corneas and Trigeminal Ganglia of Humanized HLA Transgenic Rabbits and Protect against Ocular Herpes Challenge. J Virol. 2018 08 15; 92(16). Khan AA, Srivastava R, Vahed H, Roy S, Walia SS, Kim GJ, Fouladi MA, Yamada T, Ly VT, Lam C, Lou A, Nguyen V, Boldbaatar U, Geertsema R, Fraser NW, BenMohamed L. PMID: 29899087; PMCID: PMC6069188.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    33. The wide utility of rabbits as models of human diseases. Exp Mol Med. 2018 05 22; 50(5):1-10. Esteves PJ, Abrantes J, Baldauf HM, BenMohamed L, Chen Y, Christensen N, González-Gallego J, Giacani L, Hu J, Kaplan G, Keppler OT, Knight KL, Kong XP, Lanning DK, Le Pendu J, de Matos AL, Liu J, Liu S, Lopes AM, Lu S, Lukehart S, Manabe YC, Neves F, McFadden G, Pan R, Peng X, de Sousa-Pereira P, Pinheiro A, Rahman M, Ruvoën-Clouet N, Subbian S, Tuñón MJ, van der Loo W, Vaine M, Via LE, Wang S, Mage R. PMID: 29789565; PMCID: PMC5964082.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimals
    34. Laser Adjuvant-Assisted Peptide Vaccine Promotes Skin Mobilization of Dendritic Cells and Enhances Protective CD8+ TEM and TRM Cell Responses against Herpesvirus Infection and Disease. J Virol. 2018 04 15; 92(8). Lopes PP, Todorov G, Pham TT, Nesburn AB, Bahraoui E, BenMohamed L. PMID: 29437976; PMCID: PMC5874417.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    35. CXCL17 Chemokine-Dependent Mobilization of CXCR8+CD8+ Effector Memory and Tissue-Resident Memory T Cells in the Vaginal Mucosa Is Associated with Protection against Genital Herpes. J Immunol. 2018 04 15; 200(8):2915-2926. Srivastava R, Hernández-Ruiz M, Khan AA, Fouladi MA, Kim GJ, Ly VT, Yamada T, Lam C, Sarain SAB, Boldbaatar U, Zlotnik A, Bahraoui E, BenMohamed L. PMID: 29549178; PMCID: PMC5893430.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    36. CXCL10/CXCR3-Dependent Mobilization of Herpes Simplex Virus-Specific CD8+ TEM and CD8+ TRM Cells within Infected Tissues Allows Efficient Protection against Recurrent Herpesvirus Infection and Disease. J Virol. 2017 07 15; 91(14). Srivastava R, Khan AA, Chilukuri S, Syed SA, Tran TT, Furness J, Bahraoui E, BenMohamed L. PMID: 28468883; PMCID: PMC5487556.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    37. Bolstering the Number and Function of HSV-1-Specific CD8+ Effector Memory T Cells and Tissue-Resident Memory T Cells in Latently Infected Trigeminal Ganglia Reduces Recurrent Ocular Herpes Infection and Disease. J Immunol. 2017 07 01; 199(1):186-203. Khan AA, Srivastava R, Chentoufi AA, Kritzer E, Chilukuri S, Garg S, Yu DC, Vahed H, Huang L, Syed SA, Furness JN, Tran TT, Anthony NB, McLaren CE, Sidney J, Sette A, Noelle RJ, BenMohamed L. PMID: 28539429; PMCID: PMC5515716.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    38. Airway epithelial cells enhance the immunogenicity of human myeloid dendritic cells under steady state. Clin Exp Immunol. 2017 09; 189(3):279-289. Agrawal S, Srivastava R, Rahmatpanah F, Madiraju C, BenMohamed L, Agrawal A. PMID: 28470729; PMCID: PMC5543474.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    39. Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy. Inflammation. 2017 Feb; 40(1):21-41. Nalbandian A, Khan AA, Srivastava R, Llewellyn KJ, Tan B, Shukr N, Fazli Y, Kimonis VE, BenMohamed L. PMID: 27730320; PMCID: PMC5800525.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    40. Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocular Herpesvirus Infection. J Virol. 2017 Jan 15; 91(2). Srivastava R, Khan AA, Garg S, Syed SA, Furness JN, Vahed H, Pham T, Yu HT, Nesburn AB, BenMohamed L. PMID: 27847359; PMCID: PMC5215341.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    41. A Tribute to Professor Steven L. Wechsler (1948-2016): The Man and the Scientist. Curr Eye Res. 2017 01; 42(1):161-162. Nesburn AB, BenMohamed L. PMID: 27911113; PMCID: PMC6235443.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    42. HIV-1 Tat Protein Activates both the MyD88 and TRIF Pathways To Induce Tumor Necrosis Factor Alpha and Interleukin-10 in Human Monocytes. J Virol. 2016 07 01; 90(13):5886-5898. Planès R, Ben Haij N, Leghmari K, Serrero M, BenMohamed L, Bahraoui E. PMID: 27053552; PMCID: PMC4907244.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    43. The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits. J Virol. 2016 Apr; 90(8):3913-3928. Srivastava R, Dervillez X, Khan AA, Chentoufi AA, Chilukuri S, Shukr N, Fazli Y, Ong NN, Afifi RE, Osorio N, Geertsema R, Nesburn AB, Wechsler SL, BenMohamed L. PMID: 26842468; PMCID: PMC4810530.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    44. Confocal Microscopic Analysis of a Rabbit Eye Model of High-Incidence Recurrent Herpes Stromal Keratitis. Cornea. 2016 Jan; 35(1):81-8. Jester JV, Morishige N, BenMohamed L, Brown DJ, Osorio N, Hsiang C, Perng GC, Jones C, Wechsler SL. PMID: 26555580; PMCID: PMC4674384.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    45. Prior Corneal Scarification and Injection of Immune Serum are Not Required Before Ocular HSV-1 Infection for UV-B-Induced Virus Reactivation and Recurrent Herpetic Corneal Disease in Latently Infected Mice. Curr Eye Res. 2016 06; 41(6):747-56. BenMohamed L, Osorio N, Khan AA, Srivastava R, Huang L, Krochmal JJ, Garcia JM, Simpson JL, Wechsler SL. PMID: 26398722; PMCID: PMC5349863.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    46. Significant Impact of Immunogen Design on the Diversity of Antibodies Generated by Carbohydrate-Based Anticancer Vaccine. ACS Chem Biol. 2015 Oct 16; 10(10):2364-72. Yin Z, Chowdhury S, McKay C, Baniel C, Wright WS, Bentley P, Kaczanowska K, Gildersleeve JC, Finn MG, BenMohamed L, Huang X. PMID: 26262839; PMCID: PMC4725323.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    47. A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy. PLoS One. 2015; 10(7):e0131995. Llewellyn KJ, Walker N, Nguyen C, Tan B, BenMohamed L, Kimonis VE, Nalbandian A. PMID: 26134519; PMCID: PMC4489713.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    48. Therapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of local PD-1+ TIM-3+ CD8+ exhausted T cells. J Virol. 2015 Jul; 89(13):6619-32. Khan AA, Srivastava R, Chentoufi AA, Geertsema R, Thai NT, Dasgupta G, Osorio N, Kalantari M, Nesburn AB, Wechsler SL, BenMohamed L. PMID: 25878105; PMCID: PMC4468472.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    49. HIV-1 Tat Protein Induces Production of Proinflammatory Cytokines by Human Dendritic Cells and Monocytes/Macrophages through Engagement of TLR4-MD2-CD14 Complex and Activation of NF-κB Pathway. PLoS One. 2015; 10(6):e0129425. Ben Haij N, Planès R, Leghmari K, Serrero M, Delobel P, Izopet J, BenMohamed L, Bahraoui E. PMID: 26090662; PMCID: PMC4474861.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    50. The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) protects cells against cold-shock-induced apoptosis by maintaining phosphorylation of protein kinase B (AKT). J Neurovirol. 2015 Oct; 21(5):568-75. Carpenter D, Hsiang C, Jiang X, Osorio N, BenMohamed L, Jones C, Wechsler SL. PMID: 26071090; PMCID: PMC5349860.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    51. Increased neurovirulence and reactivation of the herpes simplex virus type 1 latency-associated transcript (LAT)-negative mutant dLAT2903 with a disrupted LAT miR-H2. J Neurovirol. 2016 Feb; 22(1):38-49. Jiang X, Brown D, Osorio N, Hsiang C, BenMohamed L, Wechsler SL. PMID: 26069184; PMCID: PMC4676951.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    52. A Herpes Simplex Virus Type 1 Human Asymptomatic CD8+ T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a "Humanized" HLA Transgenic Rabbit Model. Invest Ophthalmol Vis Sci. 2015 Jun; 56(6):4013-28. Srivastava R, Khan AA, Huang J, Nesburn AB, Wechsler SL, BenMohamed L. PMID: 26098469; PMCID: PMC4477261.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    53. Decreased reactivation of a herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) mutant using the in vivo mouse UV-B model of induced reactivation. J Neurovirol. 2015 Oct; 21(5):508-17. BenMohamed L, Osorio N, Srivastava R, Khan AA, Simpson JL, Wechsler SL. PMID: 26002839; PMCID: PMC4618093.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    54. Large Amounts of Reactivated Virus in Tears Precedes Recurrent Herpes Stromal Keratitis in Stressed Rabbits Latently Infected with Herpes Simplex Virus. Curr Eye Res. 2016; 41(3):284-91. Perng GC, Osorio N, Jiang X, Geertsema R, Hsiang C, Brown D, BenMohamed L, Wechsler SL. PMID: 25859798; PMCID: PMC5349859.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    55. A herpes simplex virus type 1 mutant disrupted for microRNA H2 with increased neurovirulence and rate of reactivation. J Neurovirol. 2015 Apr; 21(2):199-209. Jiang X, Brown D, Osorio N, Hsiang C, Li L, Chan L, BenMohamed L, Wechsler SL. PMID: 25645379; PMCID: PMC4375036.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    56. HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgenic mice against ocular herpes. J Immunol. 2015 Mar 01; 194(5):2232-48. Srivastava R, Khan AA, Spencer D, Vahed H, Lopes PP, Thai NT, Wang C, Pham TT, Huang J, Scarfone VM, Nesburn AB, Wechsler SL, BenMohamed L. PMID: 25617474; PMCID: PMC4340763.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    57. Phenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpes. J Virol. 2015 Apr; 89(7):3776-92. Khan AA, Srivastava R, Spencer D, Garg S, Fremgen D, Vahed H, Lopes PP, Pham TT, Hewett C, Kuang J, Ong N, Huang L, Scarfone VM, Nesburn AB, Wechsler SL, BenMohamed L. PMID: 25609800; PMCID: PMC4403403.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    58. Age-related Defects in Ocular and Nasal Mucosal Immune System and the Immunopathology of Dry Eye Disease. Ocul Immunol Inflamm. 2016 Jun; 24(3):327-47. Farid M, Agrawal A, Fremgen D, Tao J, Chuyi H, Nesburn AB, BenMohamed L. PMID: 25535823; PMCID: PMC4478284.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    59. The challenges and opportunities for the development of a T-cell epitope-based herpes simplex vaccine. Vaccine. 2014 Nov 28; 32(50):6733-45. Kuo T, Wang C, Badakhshan T, Chilukuri S, BenMohamed L. PMID: 25446827; PMCID: PMC4254646.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    60. A cancer therapeutic vaccine based on clustered Tn-antigen mimetics induces strong antibody-mediated protective immunity. Angew Chem Int Ed Engl. 2014 Oct 27; 53(44):11917-20. Richichi B, Thomas B, Fiore M, Bosco R, Qureshi H, Nativi C, Renaudet O, BenMohamed L. PMID: 25168881; PMCID: PMC4564297.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    61. Associations of HLA-A, HLA-B and HLA-C alleles frequency with prevalence of herpes simplex virus infections and diseases across global populations: implication for the development of an universal CD8+ T-cell epitope-based vaccine. Hum Immunol. 2014 Aug; 75(8):715-29. Samandary S, Kridane-Miledi H, Sandoval JS, Choudhury Z, Langa-Vives F, Spencer D, Chentoufi AA, Lemonnier FA, BenMohamed L. PMID: 24798939; PMCID: PMC4119854.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    62. Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state. Mucosal Immunol. 2014 Nov; 7(6):1386-94. Prakash S, Agrawal S, Vahed H, Ngyuen M, BenMohamed L, BenMohamad L, Gupta S, Agrawal A. PMID: 24759206; PMCID: PMC4205198.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCellsCTClinical Trials
    63. HIV-1 Tat protein induces PD-L1 (B7-H1) expression on dendritic cells through tumor necrosis factor alpha- and toll-like receptor 4-mediated mechanisms. J Virol. 2014 Jun; 88(12):6672-89. Planès R, BenMohamed L, Leghmari K, Delobel P, Izopet J, Bahraoui E. PMID: 24696476; PMCID: PMC4054384.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    64. Asymptomatic memory CD8+ T cells: from development and regulation to consideration for human vaccines and immunotherapeutics. Hum Vaccin Immunother. 2014; 10(4):945-63. Khan AA, Srivastava R, Lopes PP, Wang C, Pham TT, Cochrane J, Thai NT, Gutierrez L, Benmohamed L. PMID: 24499824; PMCID: PMC4896594.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    65. Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes. J Immunol. 2013 Nov 15; 191(10):5124-38. Dervillez X, Qureshi H, Chentoufi AA, Khan AA, Kritzer E, Yu DC, Diaz OR, Gottimukkala C, Kalantari M, Villacres MC, Scarfone VM, McKinney DM, Sidney J, Sette A, Nesburn AB, Wechsler SL, BenMohamed L. PMID: 24101547; PMCID: PMC4057607.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    66. Cytokine profiling in patients with VCP-associated disease. Clin Transl Sci. 2014 Feb; 7(1):29-32. Dec E, Rana P, Katheria V, Dec R, Khare M, Nalbandian A, Leu SY, Radom-Aizik S, Llewellyn K, BenMohamed L, Zaldivar F, Kimonis V. PMID: 24119107; PMCID: PMC4057603.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    67. HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 monochain transgenic/H-2 class I null mice: novel versatile preclinical models of human T cell responses. J Immunol. 2013 Jul 15; 191(2):583-93. Boucherma R, Kridane-Miledi H, Bouziat R, Rasmussen M, Gatard T, Langa-Vives F, Lemercier B, Lim A, Bérard M, Benmohamed L, Buus S, Rooke R, Lemonnier FA. PMID: 23776170; PMCID: PMC4057605.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    68. Boosting immunity to small tumor-associated carbohydrates with bacteriophage qβ capsids. ACS Chem Biol. 2013; 8(6):1253-62. Yin Z, Comellas-Aragones M, Chowdhury S, Bentley P, Kaczanowska K, Benmohamed L, Gildersleeve JC, Finn MG, Huang X. PMID: 23505965; PMCID: PMC3735802.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    69. Immunity to ocular and genital herpes simplex viruses infections. Clin Dev Immunol. 2012; 2012:732546. Chentoufi AA, BenMohamed L, Van De Perre P, Ashkar AA. PMID: 23326289; PMCID: PMC3541643.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    70. Mucosal herpes immunity and immunopathology to ocular and genital herpes simplex virus infections. Clin Dev Immunol. 2012; 2012:149135. Chentoufi AA, Benmohamed L. PMID: 23320014; PMCID: PMC3540975.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    71. Targeting the genital tract mucosa with a lipopeptide/recombinant adenovirus prime/boost vaccine induces potent and long-lasting CD8+ T cell immunity against herpes: importance of MyD88. J Immunol. 2012 Nov 01; 189(9):4496-509. Zhang X, Dervillez X, Chentoufi AA, Badakhshan T, Bettahi I, Benmohamed L. PMID: 23018456; PMCID: PMC3478413.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    72. The herpes simplex virus type 1 latency-associated transcript inhibits phenotypic and functional maturation of dendritic cells. Viral Immunol. 2012 Jun; 25(3):204-15. Chentoufi AA, Dervillez X, Dasgupta G, Nguyen C, Kabbara KW, Jiang X, Nesburn AB, Wechsler SL, Benmohamed L. PMID: 22512280; PMCID: PMC3366336.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    73. Future of an "Asymptomatic" T-cell Epitope-Based Therapeutic Herpes Simplex Vaccine. Future Virol. 2012 Apr 01; 7(4):371-378. Dervillez X, Gottimukkala C, Kabbara KW, Nguyen C, Badakhshan T, Kim SM, Nesburn AB, Wechsler SL, Benmohamed L. PMID: 22701511; PMCID: PMC3372919.
      View in: PubMed   Mentions: 27  
    74. Towards a rational design of an asymptomatic clinical herpes vaccine: the old, the new, and the unknown. Clin Dev Immunol. 2012; 2012:187585. Chentoufi AA, Kritzer E, Yu DM, Nesburn AB, Benmohamed L. PMID: 22548113; PMCID: PMC3324142.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCellsPHPublic Health
    75. Immunodominant "asymptomatic" herpes simplex virus 1 and 2 protein antigens identified by probing whole-ORFome microarrays with serum antibodies from seropositive asymptomatic versus symptomatic individuals. J Virol. 2012 Apr; 86(8):4358-69. Dasgupta G, Chentoufi AA, Kalantari M, Falatoonzadeh P, Chun S, Lim CH, Felgner PL, Davies DH, BenMohamed L. PMID: 22318137; PMCID: PMC3318627.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    76. Discovery of potential diagnostic and vaccine antigens in herpes simplex virus 1 and 2 by proteome-wide antibody profiling. J Virol. 2012 Apr; 86(8):4328-39. Kalantari-Dehaghi M, Chun S, Chentoufi AA, Pablo J, Liang L, Dasgupta G, Molina DM, Jasinskas A, Nakajima-Sasaki R, Felgner J, Hermanson G, BenMohamed L, Felgner PL, Davies DH. PMID: 22318154; PMCID: PMC3318641.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    77. Current trends in negative immuno-synergy between two sexually transmitted infectious viruses: HIV-1 and HSV-1/2. Curr Trends Immunol. 2012; 13:51-68. Chentoufi AA, Dervillez X, Rubbo PA, Kuo T, Zhang X, Nagot N, Tuaillon E, Van De Perre P, Nesburn AB, Benmohamed L. PMID: 23355766; PMCID: PMC3552495.
      View in: PubMed   Mentions: 11  
    78. HIV-1 infection impairs HSV-specific CD4(+) and CD8(+) T-cell response by reducing Th1 cytokines and CCR5 ligand secretion. J Acquir Immune Defic Syndr. 2011 Sep 01; 58(1):9-17. Rubbo PA, Tuaillon E, Nagot N, Chentoufi AA, Bolloré K, Reynes J, Vendrell JP, BenMohamed L, Van De Perre P. PMID: 21646911.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    79. CD11c controls herpes simplex virus 1 responses to limit virus replication during primary infection. J Virol. 2011 Oct; 85(19):9945-55. Allen SJ, Mott KR, Chentoufi AA, BenMohamed L, Wechsler SL, Ballantyne CM, Ghiasi H. PMID: 21775452; PMCID: PMC3196403.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    80. The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism. J Virol. 2011 Sep; 85(17):9127-38. Chentoufi AA, Kritzer E, Tran MV, Dasgupta G, Lim CH, Yu DC, Afifi RE, Jiang X, Carpenter D, Osorio N, Hsiang C, Nesburn AB, Wechsler SL, BenMohamed L. PMID: 21715478; PMCID: PMC3165846.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    81. Of mice and not humans: how reliable are animal models for evaluation of herpes CD8(+)-T cell-epitopes-based immunotherapeutic vaccine candidates? Vaccine. 2011 Aug 11; 29(35):5824-36. Dasgupta G, BenMohamed L. PMID: 21718746; PMCID: PMC3159167.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    82. Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses. Invest Ophthalmol Vis Sci. 2011 May 17; 52(6):3321-33. Dasgupta G, Chentoufi AA, You S, Falatoonzadeh P, Urbano LA, Akhtarmalik A, Nguyen K, Ablabutyan L, Nesburn AB, BenMohamed L. PMID: 21273544; PMCID: PMC3109031.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    83. The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1. J Virol. 2011 May; 85(9):4184-97. Allen SJ, Hamrah P, Gate D, Mott KR, Mantopoulos D, Zheng L, Town T, Jones C, von Andrian UH, Freeman GJ, Sharpe AH, BenMohamed L, Ahmed R, Wechsler SL, Ghiasi H. PMID: 21307196; PMCID: PMC3126262.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    84. Interferon-γ, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity. Malar J. 2011 Feb 08; 10:27. Perlaza BL, Sauzet JP, Brahimi K, BenMohamed L, Druilhe P. PMID: 21303495; PMCID: PMC3046914.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    85. The herpes simplex virus type 1 latency-associated transcript can protect neuron-derived C1300 and Neuro2A cells from granzyme B-induced apoptosis and CD8 T-cell killing. J Virol. 2011 Mar; 85(5):2325-32. Jiang X, Chentoufi AA, Hsiang C, Carpenter D, Osorio N, BenMohamed L, Fraser NW, Jones C, Wechsler SL. PMID: 21177822; PMCID: PMC3067767.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    86. Future viral vectors for the delivery of asymptomatic herpes epitope-based immunotherapeutic vaccines. Future Virol. 2010 Sep 01; 5(5):525-528. Chentoufi AA, BenMohamed L. PMID: 21442030; PMCID: PMC3063648.
      View in: PubMed   Mentions: 20  
    87. Linear and branched glyco-lipopeptide vaccines follow distinct cross-presentation pathways and generate different magnitudes of antitumor immunity. PLoS One. 2010 Jun 21; 5(6):e11216. Renaudet O, Dasgupta G, Bettahi I, Shi A, Nesburn AB, Dumy P, BenMohamed L. PMID: 20574522; PMCID: PMC2888579.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    88. A novel HLA (HLA-A*0201) transgenic rabbit model for preclinical evaluation of human CD8+ T cell epitope-based vaccines against ocular herpes. J Immunol. 2010 Mar 01; 184(5):2561-71. Chentoufi AA, Dasgupta G, Christensen ND, Hu J, Choudhury ZS, Azeem A, Jester JV, Nesburn AB, Wechsler SL, BenMohamed L. PMID: 20124097; PMCID: PMC3752373.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    89. Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization. Clin Vaccine Immunol. 2010 Mar; 17(3):342-53. Chentoufi AA, Dasgupta G, Nesburn AB, Bettahi I, Binder NR, Choudhury ZS, Chamberlain WD, Wechsler SL, BenMohamed L. PMID: 20089796; PMCID: PMC2837957.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCellsPHPublic Health
    90. Developing an asymptomatic mucosal herpes vaccine: the present and the future. Future Microbiol. 2010 Jan; 5(1):1-4. Dasgupta G, Nesburn AB, Wechsler SL, BenMohamed L. PMID: 20020824; PMCID: PMC4512283.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    91. Recent advances in multivalent self adjuvanting glycolipopeptide vaccine strategies against breast cancer. Arch Immunol Ther Exp (Warsz). 2009 Nov-Dec; 57(6):409-23. Chentoufi AA, Nesburn AB, BenMohamed L. PMID: 19866342.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    92. New concepts in herpes simplex virus vaccine development: notes from the battlefield. Expert Rev Vaccines. 2009 Aug; 8(8):1023-35. Dasgupta G, Chentoufi AA, Nesburn AB, Wechsler SL, BenMohamed L. PMID: 19627185; PMCID: PMC2760836.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    93. The role of a glycoprotein K (gK) CD8+ T-cell epitope of herpes simplex virus on virus replication and pathogenicity. Invest Ophthalmol Vis Sci. 2009 Jun; 50(6):2903-12. Mott KR, Chentoufi AA, Carpenter D, BenMohamed L, Wechsler SL, Ghiasi H. PMID: 19168902.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCellsPHPublic Health
    94. A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge. Mucosal Immunol. 2009 Mar; 2(2):129-143. Zhang X, Chentoufi AA, Dasgupta G, Nesburn AB, Wu M, Zhu X, Carpenter D, Wechsler SL, You S, BenMohamed L. PMID: 19129756; PMCID: PMC4509510.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    95. Level of herpes simplex virus type 1 latency correlates with severity of corneal scarring and exhaustion of CD8+ T cells in trigeminal ganglia of latently infected mice. J Virol. 2009 Mar; 83(5):2246-54. Mott KR, Bresee CJ, Allen SJ, BenMohamed L, Wechsler SL, Ghiasi H. PMID: 19091870; PMCID: PMC2643740.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    96. Asymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein B. J Virol. 2008 Dec; 82(23):11792-802. Chentoufi AA, Binder NR, Berka N, Durand G, Nguyen A, Bettahi I, Maillère B, BenMohamed L. PMID: 18799581; PMCID: PMC2583686.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    97. Gender-dependent HLA-DR-restricted epitopes identified from herpes simplex virus type 1 glycoprotein D. Clin Vaccine Immunol. 2008 Sep; 15(9):1436-49. Zhang X, Castelli FA, Zhu X, Wu M, Maillère B, BenMohamed L. PMID: 18667634; PMCID: PMC2546687.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    98. Antitumor activity of a self-adjuvanting glyco-lipopeptide vaccine bearing B cell, CD4+ and CD8+ T cell epitopes. Cancer Immunol Immunother. 2009 Feb; 58(2):187-200. Bettahi I, Dasgupta G, Renaudet O, Chentoufi AA, Zhang X, Carpenter D, Yoon S, Dumy P, BenMohamed L. PMID: 18584174; PMCID: PMC11030914.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    99. Towards a self-adjuvanting multivalent B and T cell epitope containing synthetic glycolipopeptide cancer vaccine. ChemMedChem. 2008 May; 3(5):737-41. Renaudet O, BenMohamed L, Dasgupta G, Bettahi I, Dumy P. PMID: 18205167.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    100. HLA-A*0201-restricted CD8+ cytotoxic T lymphocyte epitopes identified from herpes simplex virus glycoprotein D. J Immunol. 2008 Jan 01; 180(1):426-37. Chentoufi AA, Zhang X, Lamberth K, Dasgupta G, Bettahi I, Nguyen A, Wu M, Zhu X, Mohebbi A, Buus S, Wechsler SL, Nesburn AB, BenMohamed L. PMID: 18097044.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    101. Protective immunity against ocular herpes infection and disease induced by highly immunogenic self-adjuvanting glycoprotein D lipopeptide vaccines. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4643-53. Bettahi I, Nesburn AB, Yoon S, Zhang X, Mohebbi A, Sue V, Vanderberg A, Wechsler SL, BenMohamed L. PMID: 17898288.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCellsPHPublic Health
    102. Stable cell lines expressing high levels of the herpes simplex virus type 1 LAT are refractory to caspase 3 activation and DNA laddering following cold shock induced apoptosis. Virology. 2007 Dec 05; 369(1):12-8. Carpenter D, Hsiang C, Brown DJ, Jin L, Osorio N, BenMohamed L, Jones C, Wechsler SL. PMID: 17727910; PMCID: PMC2276668.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    103. Introducing point mutations into the ATGs of the putative open reading frames of the HSV-1 gene encoding the latency associated transcript (LAT) reduces its anti-apoptosis activity. Microb Pathog. 2008 Feb; 44(2):98-102. Carpenter D, Henderson G, Hsiang C, Osorio N, BenMohamed L, Jones C, Wechsler SL. PMID: 17900852; PMCID: PMC2291025.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    104. Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection. J Virol. 2007 Jul; 81(14):7647-61. Nesburn AB, Bettahi I, Dasgupta G, Chentoufi AA, Zhang X, You S, Morishige N, Wahlert AJ, Brown DJ, Jester JV, Wechsler SL, BenMohamed L. PMID: 17475646; PMCID: PMC1933381.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    105. Topical/mucosal delivery of sub-unit vaccines that stimulate the ocular mucosal immune system. Ocul Surf. 2006 Oct; 4(4):178-87. Nesburn AB, Bettahi I, Zhang X, Zhu X, Chamberlain W, Afifi RE, Wechsler SL, BenMohamed L. PMID: 17146573.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsPHPublic Health
    106. Protective immunity to genital herpes simplex virus type 1 and type 2 provided by self-adjuvanting lipopeptides that drive dendritic cell maturation and elicit a polarized Th1 immune response. Viral Immunol. 2006; 19(2):220-36. Bettahi I, Zhang X, Afifi RE, BenMohamed L. PMID: 16817765.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    107. Th-cytotoxic T-lymphocyte chimeric epitopes extended by Nepsilon-palmitoyl lysines induce herpes simplex virus type 1-specific effector CD8+ Tc1 responses and protect against ocular infection. J Virol. 2005 Dec; 79(24):15289-301. Zhang X, Issagholian A, Berg EA, Fishman JB, Nesburn AB, BenMohamed L. PMID: 16306600; PMCID: PMC1316035.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    108. The locus encompassing the latency-associated transcript of herpes simplex virus type 1 interferes with and delays interferon expression in productively infected neuroblastoma cells and trigeminal Ganglia of acutely infected mice. J Virol. 2005 May; 79(10):6162-71. Peng W, Henderson G, Inman M, BenMohamed L, Perng GC, Wechsler SL, Jones C. PMID: 15858001; PMCID: PMC1091686.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    109. Local and systemic B cell and Th1 responses induced following ocular mucosal delivery of multiple epitopes of herpes simplex virus type 1 glycoprotein D together with cytosine-phosphate-guanine adjuvant. Vaccine. 2005 Jan 04; 23(7):873-83. Nesburn AB, Ramos TV, Zhu X, Asgarzadeh H, Nguyen V, BenMohamed L. PMID: 15603887.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    110. Lipopeptide epitopes extended by an Nepsilon-palmitoyl-lysine moiety increase uptake and maturation of dendritic cells through a Toll-like receptor-2 pathway and trigger a Th1-dependent protective immunity. Eur J Immunol. 2004 Nov; 34(11):3102-14. Zhu X, Ramos TV, Gras-Masse H, Kaplan BE, BenMohamed L. PMID: 15368273.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCellsPHPublic Health
    111. Long-term multiepitopic cytotoxic-T-lymphocyte responses induced in chimpanzees by combinations of Plasmodium falciparum liver-stage peptides and lipopeptides. Infect Immun. 2004 Aug; 72(8):4376-84. BenMohamed L, Thomas A, Druilhe P. PMID: 15271893; PMCID: PMC470687.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    112. A fully synthetic therapeutic vaccine candidate targeting carcinoma-associated Tn carbohydrate antigen induces tumor-specific antibodies in nonhuman primates. Cancer Res. 2004 Jul 15; 64(14):4987-94. Lo-Man R, Vichier-Guerre S, Perraut R, Dériaud E, Huteau V, BenMohamed L, Diop OM, Livingston PO, Bay S, Leclerc C. PMID: 15256473.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    113. Identification of novel immunodominant CD4+ Th1-type T-cell peptide epitopes from herpes simplex virus glycoprotein D that confer protective immunity. J Virol. 2003 Sep; 77(17):9463-73. BenMohamed L, Bertrand G, McNamara CD, Gras-Masse H, Hammer J, Wechsler SL, Nesburn AB. PMID: 12915561; PMCID: PMC187395.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCellsPHPublic Health
    114. Induction of carbohydrate-specific antibodies in HLA-DR transgenic mice by a synthetic glycopeptide: a potential anti cancer vaccine for human use. J Pept Res. 2003 Sep; 62(3):117-24. Vichier-Guerre S, Lo-Man R, BenMohamed L, Dériaud E, Kovats S, Leclerc C, Bay S. PMID: 12895273.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    115. A novel herpes simplex virus type 1 transcript (AL-RNA) antisense to the 5' end of the latency-associated transcript produces a protein in infected rabbits. J Virol. 2002 Aug; 76(16):8003-10. Perng GC, Maguen B, Jin L, Mott KR, Kurylo J, BenMohamed L, Yukht A, Osorio N, Nesburn AB, Henderson G, Inman M, Jones C, Wechsler SL. PMID: 12134005; PMCID: PMC155148.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    116. Systemic immune responses induced by mucosal administration of lipopeptides without adjuvant. Eur J Immunol. 2002 Aug; 32(8):2274-81. BenMohamed L, Belkaid Y, Loing E, Brahimi K, Gras-Masse H, Druilhe P. PMID: 12209640.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCellsPHPublic Health
    117. Lipopeptide vaccines--yesterday, today, and tomorrow. Lancet Infect Dis. 2002 Jul; 2(7):425-31. BenMohamed L, Wechsler SL, Nesburn AB. PMID: 12127354.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    118. Intranasal administration of a synthetic lipopeptide without adjuvant induces systemic immune responses. Immunology. 2002 May; 106(1):113-21. BenMohamed L, Krishnan R, Auge C, Primus JF, Diamond DJ. PMID: 11972639; PMCID: PMC1782698.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    119. Human antibodies against Plasmodium falciparum liver-stage antigen 3 cross-react with Plasmodium yoelii preerythrocytic-stage epitopes and inhibit sporozoite invasion in vitro and in vivo. Infect Immun. 2001 Jun; 69(6):3845-52. Brahimi K, Badell E, Sauzet JP, BenMohamed L, Daubersies P, Guérin-Marchand C, Snounou G, Druilhe P. PMID: 11349050; PMCID: PMC98406.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    120. Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3. Nat Med. 2000 Nov; 6(11):1258-63. Daubersies P, Thomas AW, Millet P, Brahimi K, Langermans JA, Ollomo B, BenMohamed L, Slierendregt B, Eling W, Van Belkum A, Dubreuil G, Meis JF, Guérin-Marchand C, Cayphas S, Cohen J, Gras-Masse H, Druilhe P, Mohamed LB. PMID: 11062538.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    121. Induction of CTL response by a minimal epitope vaccine in HLA A*0201/DR1 transgenic mice: dependence on HLA class II restricted T(H) response. Hum Immunol. 2000 Aug; 61(8):764-79. BenMohamed L, Krishnan R, Longmate J, Auge C, Low L, Primus J, Diamond DJ. PMID: 10980387.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    122. High immunogenicity in chimpanzees of peptides and lipopeptides derived from four new Plasmodium falciparum pre-erythrocytic molecules. Vaccine. 2000 Jun 15; 18(25):2843-55. Benmohamed L, Thomas A, Bossus M, Brahimi K, Wubben J, Gras-Masse H, Druilhe P. PMID: 10812228.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    123. Lipopeptide immunization without adjuvant induces potent and long-lasting B, T helper, and cytotoxic T lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees. Eur J Immunol. 1997 May; 27(5):1242-53. BenMohamed L, Gras-Masse H, Tartar A, Daubersies P, Brahimi K, Bossus M, Thomas A, Druilhe P. PMID: 9174617.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    124. Improved detection of human antibodies to a Plasmodium antigen using a peptide modified with Aib residues. J Pept Sci. 1997 Jan-Feb; 3(1):47-53. Bossus M, BenMohamed L, Londono A, Barbier B, Tartar A, Druilhe P, Gras-Masse H, Mohammed L. PMID: 9230470.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    125. A novel Plasmodium falciparum sporozoite and liver stage antigen (SALSA) defines major B, T helper, and CTL epitopes. J Immunol. 1996 Apr 15; 156(8):2874-84. Bottius E, BenMohamed L, Brahimi K, Gras H, Lepers JP, Raharimalala L, Aikawa M, Meis J, Slierendregt B, Tartar A, Thomas A, Druilhe P. PMID: 8609407.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    126. Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T cell determinants. J Immunol. 1994 Jul 01; 153(1):190-204. Fidock DA, Gras-Masse H, Lepers JP, Brahimi K, Benmohamed L, Mellouk S, Guerin-Marchand C, Londono A, Raharimalala L, Meis JF, et al. PMID: 7515922.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
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