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Gupta, Sudhir

TitleProfessor
InstitutionUniversity of California, Irvine
DepartmentMedicine
Address1001 Health Sciences Road
CA 92697-3950
Phone(949) 824-5818, 8600
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    Collapse Research 
    Collapse Research Activities and Funding
    TNF-Induced Apoptosis of Lymphocytes in Aged Humans
    NIH/NIA R01AG018313Jun 1, 2002 - Apr 30, 2006
    Role: Principal Investigator
    CELL CYCLE &PROGRAMMED CELL DEATH IN THE IMMUNE SYSTEM
    NIH/NIAID R13AI039530Feb 1, 1996 - Jan 31, 1997
    Role: Principal Investigator
    CONFERENCE ON LYMPHOCYTE ACTIVATION &IMMUNOREGULATION
    NIH/NIAID R13AI029498Feb 15, 1990 - Feb 14, 1991
    Role: Principal Investigator
    CYCLOSPORINE A AND SIGNAL TRANSDUCTION
    NIH/NIAID R01AI026465Jul 1, 1988 - Mar 31, 1992
    Role: Principal Investigator
    CONFERENCE ON LYMPHOCYTE ACTIVATION/IMMUNE REGULATION
    NIH/NIAID R13AI025809Sep 30, 1987 - Aug 31, 1988
    Role: Principal Investigator
    CONFERENCE ON LYMPHOCYTE ACTIVATION &IMMUNOLOGY
    NIH/NIAID R13AI023582Feb 26, 1986 - Feb 25, 1987
    Role: Principal Investigator
    CELLULAR AND MOLECULAR INTERACTIONS IN AGING HUMANS
    NIH/NIA R01AG004361Apr 1, 1984 - Nov 30, 1987
    Role: Principal Investigator
    AMLR AND LYMPHOID DIFFERENTIATION IN AIDS
    NIH/NIAID R01AI020717Sep 15, 1983 - Mar 31, 1987
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Gupta S, Su H, Agrawal S, Gollapudi S. Molecular changes associated with increased TNF-a-induced apoptotis in naïve (TN) and central memory (TCM) CD8+ T cells in aged humans. Immun Ageing. 2018; 15:2. PMID: 29387134.
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    2. Hamadani S, Wang B, Gupta S. IgG4-related disease presenting as hoarseness and postcricoid ulcer. Ann Allergy Asthma Immunol. 2018 Feb; 120(2):211-212. PMID: 29217085.
      View in: PubMed
    3. Gupta S, Gupta A. Selective IgM Deficiency-An Underestimated Primary Immunodeficiency. Front Immunol. 2017; 8:1056. PMID: 28928736.
      View in: PubMed
    4. Agrawal A, Agrawal S, Gupta S. Role of Dendritic Cells in Inflammation and Loss of Tolerance in the Elderly. Front Immunol. 2017; 8:896. PMID: 28798751.
      View in: PubMed
    5. Gupta S, Agrawal S, Gollapudi S, Kubagawa H. FcµR in human B cell subsets in primary selective IgM deficiency, and regulation of FcµR and production of natural IgM antibodies by IGIV. Hum Immunol. 2016 Dec; 77(12):1194-1201. PMID: 27751883.
      View in: PubMed
    6. Williams SJ, Gupta S. Anaphylaxis to IVIG. Arch Immunol Ther Exp (Warsz). 2017 Feb; 65(1):11-19. PMID: 27412077.
      View in: PubMed
    7. Gharib A, Caperton C, Gupta S. Anaphylaxis to IGIV in immunoglobulin-naïve common variable immunodeficiency patient in the absence of IgG anti-IgA antibodies: successful administration of low IgA-containing immunoglobulin. Allergy Asthma Clin Immunol. 2016; 12:23. PMID: 27190527; PMCID: PMC4869305.
    8. Gupta S. Ins and Outs of Antibodies. J Clin Immunol. 2016 May; 36 Suppl 1:1-4. PMID: 27169867.
      View in: PubMed
    9. Gollapudi S, Gupta S. Reversal of oxidative stress-induced apoptosis in T and B lymphocytes by Coenzyme Q10 (CoQ10). Am J Clin Exp Immunol. 2016; 5(2):41-7. PMID: 27168954; PMCID: PMC4858601.
    10. Louis AG, Agrawal S, Gupta S. Analysis of subsets of B cells, Breg, CD4Treg and CD8Treg cells in adult patients with primary selective IgM deficiency. Am J Clin Exp Immunol. 2016; 5(1):21-32. PMID: 27168952; PMCID: PMC4858603.
    11. Louis AG, Yel L, Cao JN, Agrawal S, Gupta S. Common variable immunodeficiency associated with microdeletion of chromosome 1q42.1-q42.3 and inositol 1,4,5-trisphosphate kinase B (ITPKB) deficiency. Clin Transl Immunology. 2016 Jan; 5(1):e59. PMID: 26900472.
      View in: PubMed
    12. Caperton C, Agrawal S, Gupta S. Good syndrome presenting with CD8? T-Cell large granular lymphocyte leukemia. Oncotarget. 2015 Nov 03; 6(34):36577-86. PMID: 26429871; PMCID: PMC4742196.
    13. Gharib A, Louis AG, Agrawal S, Gupta S. Syndrome of selective IgM deficiency with severe T cell deficiency associated with disseminated cutaneous mycobacterium avium intracellulaire infection. Am J Clin Exp Immunol. 2015; 4(2):15-27. PMID: 26550546; PMCID: PMC4620120.
    14. Wei C, Kim IK, Li L, Wu L, Gupta S. Thymosin Beta 4 protects mice from monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy. PLoS One. 2014; 9(11):e110598. PMID: 25412097; PMCID: PMC4239012.
    15. Cao JN, Agrawal A, Sharman E, Jia Z, Gupta S. Alterations in gene array patterns in dendritic cells from aged humans. PLoS One. 2014; 9(9):e106471. PMID: 25191744; PMCID: PMC4156347.
    16. Prakash S, Agrawal S, Ma D, Gupta S, Peterson EM, Agrawal A. Dendritic cells from aged subjects display enhanced inflammatory responses to Chlamydophila pneumoniae. Mediators Inflamm. 2014; 2014:436438. PMID: 25253920; PMCID: PMC4165882.
    17. Gupta S, Schwarz HP. The science and arts of antibodies. J Clin Immunol. 2014 Jul; 34 Suppl 1:S1-3. PMID: 24760115.
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    18. Thakur S, Li L, Gupta S. NF-?B-mediated integrin-linked kinase regulation in angiotensin II-induced pro-fibrotic process in cardiac fibroblasts. Life Sci. 2014 Jun 27; 107(1-2):68-75. PMID: 24802124.
      View in: PubMed
    19. Louis AG, Gupta S. Primary selective IgM deficiency: an ignored immunodeficiency. Clin Rev Allergy Immunol. 2014 Apr; 46(2):104-11. PMID: 23760686.
      View in: PubMed
    20. Li L, Wei C, Kim IK, Janssen-Heininger Y, Gupta S. Inhibition of nuclear factor-?B in the lungs prevents monocrotaline-induced pulmonary hypertension in mice. Hypertension. 2014 Jun; 63(6):1260-9. PMID: 24614212.
      View in: PubMed
    21. Gupta S. Role of dendritic cells in innate and adaptive immune response in human aging. Exp Gerontol. 2014 Jun; 54:47-52. PMID: 24370374.
      View in: PubMed
    22. Gupta S, Agrawal A. Inflammation & autoimmunity in human ageing: dendritic cells take a center stage. Indian J Med Res. 2013 Nov; 138(5):711-6. PMID: 24434323; PMCID: PMC3928701.
    23. Wei C, Li L, Gupta S. NF-?B-mediated miR-30b regulation in cardiomyocytes cell death by targeting Bcl-2. Mol Cell Biochem. 2014 Feb; 387(1-2):135-41. PMID: 24178239.
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    24. Gupta S, Louis AG. Tolerance and autoimmunity in primary immunodeficiency disease: a comprehensive review. Clin Rev Allergy Immunol. 2013 Oct; 45(2):162-9. PMID: 23296947.
      View in: PubMed
    25. Agrawal S, Gollapudi S, Gupta S, Agrawal A. Dendritic cells from the elderly display an intrinsic defect in the production of IL-10 in response to lithium chloride. Exp Gerontol. 2013 Nov; 48(11):1285-92. PMID: 23988651.
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    26. Wei C, Henderson H, Spradley C, Li L, Kim IK, Kumar S, Hong N, Arroliga AC, Gupta S. Circulating miRNAs as potential marker for pulmonary hypertension. PLoS One. 2013; 8(5):e64396. PMID: 23717609; PMCID: PMC3662705.
    27. Gupta S, Agrawal S, Gollapudi S. Increased activation and cytokine secretion in B cells stimulated with leptin in aged humans. Immun Ageing. 2013 Jan 23; 10(1):3. PMID: 23343052; PMCID: PMC3557206.
    28. Prakash S, Agrawal S, Cao JN, Gupta S, Agrawal A. Impaired secretion of interferons by dendritic cells from aged subjects to influenza : role of histone modifications. Age (Dordr). 2013 Oct; 35(5):1785-97. PMID: 23007963; PMCID: PMC3776111.
    29. Agrawal A, Su H, Chen J, Osann K, Agrawal S, Gupta S. Increased IL-21 secretion by aged CD4+T cells is associated with prolonged STAT-4 activation and CMV seropositivity. Aging (Albany NY). 2012 Sep; 4(9):648-59. PMID: 23064011; PMCID: PMC3492228.
    30. Wei C, Kumar S, Kim IK, Gupta S. Thymosin beta 4 protects cardiomyocytes from oxidative stress by targeting anti-oxidative enzymes and anti-apoptotic genes. PLoS One. 2012; 7(8):e42586. PMID: 22880044; PMCID: PMC3411836.
    31. Gupta S, Samra D, Yel L, Agrawal S. T and B cell deficiency associated with yellow nail syndrome. Scand J Immunol. 2012 Mar; 75(3):329-35. PMID: 21995335.
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    32. Kumar S, Wei C, Thomas CM, Kim IK, Seqqat R, Kumar R, Baker KM, Jones WK, Gupta S. Cardiac-specific genetic inhibition of nuclear factor-?B prevents right ventricular hypertrophy induced by monocrotaline. Am J Physiol Heart Circ Physiol. 2012 Apr 15; 302(8):H1655-66. PMID: 22245771.
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    33. Gupta S, Madkaikar M, Singh S, Sehgal S. Primary immunodeficiencies in India: a perspective. Ann N Y Acad Sci. 2012 Feb; 1250:73-9. PMID: 22224794.
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    34. Kumar S, Gupta S. Thymosin beta 4 prevents oxidative stress by targeting antioxidant and anti-apoptotic genes in cardiac fibroblasts. PLoS One. 2011; 6(10):e26912. PMID: 22046407; PMCID: PMC3201979.
    35. Sopko N, Qin Y, Finan A, Dadabayev A, Chigurupati S, Qin J, Penn MS, Gupta S. Significance of thymosin ß4 and implication of PINCH-1-ILK-a-parvin (PIP) complex in human dilated cardiomyopathy. PLoS One. 2011; 6(5):e20184. PMID: 21625516; PMCID: PMC3098280.
    36. Agrawal S, Gollapudi S, Su H, Gupta S. Leptin activates human B cells to secrete TNF-a, IL-6, and IL-10 via JAK2/STAT3 and p38MAPK/ERK1/2 signaling pathway. J Clin Immunol. 2011 Jun; 31(3):472-8. PMID: 21243519; PMCID: PMC3132280.
    37. Gupta S. A farewell. J Clin Immunol. 2010 Nov; 30(6):775-6. PMID: 20953682; PMCID: PMC2970814.
    38. Agrawal S, Gupta S, Agrawal A. Human dendritic cells activated via dectin-1 are efficient at priming Th17, cytotoxic CD8 T and B cell responses. PLoS One. 2010 Oct 18; 5(10):e13418. PMID: 20976143; PMCID: PMC2956651.
    39. Sridharan A, Esposo M, Kaushal K, Tay J, Osann K, Agrawal S, Gupta S, Agrawal A. Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity. Age (Dordr). 2011 Sep; 33(3):363-76. PMID: 20953722; PMCID: PMC3168606.
    40. Agrawal S, Gupta S. TLR1/2, TLR7, and TLR9 signals directly activate human peripheral blood naive and memory B cell subsets to produce cytokines, chemokines, and hematopoietic growth factors. J Clin Immunol. 2011 Feb; 31(1):89-98. PMID: 20821041; PMCID: PMC3064903.
    41. Nyugen J, Agrawal S, Gollapudi S, Gupta S. Impaired functions of peripheral blood monocyte subpopulations in aged humans. J Clin Immunol. 2010 Nov; 30(6):806-13. PMID: 20703784; PMCID: PMC2970801.
    42. Agrawal A, Gupta S. Impact of aging on dendritic cell functions in humans. Ageing Res Rev. 2011 Jul; 10(3):336-45. PMID: 20619360; PMCID: PMC3030666.
    43. Gupta S. Antibodies: basic mechanisms and emerging concepts. J Clin Immunol. 2010 May; 30 Suppl 1:S1-3. PMID: 20387105.
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    44. Gupta S, Samra D, Agrawal S. Adaptive and Innate Immune Responses in Autism: Rationale for Therapeutic Use of Intravenous Immunoglobulin. J Clin Immunol. 2010 May; 30 Suppl 1:S90-6. PMID: 20393790.
      View in: PubMed
    45. Agrawal A, Tay J, Yang GE, Agrawal S, Gupta S. Age-associated epigenetic modifications in human DNA increase its immunogenicity. Aging (Albany NY). 2010 Mar 20; 2(2):93-100. PMID: 20354270; PMCID: PMC2850145.
    46. Hong R, Agrawal S, Gollapudi S, Gupta S. Impaired pneumovax-23-induced monocyte-derived cytokine production in patients with common variable immunodeficiency. J Clin Immunol. 2010 May; 30(3):435-41. PMID: 20177958.
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    47. Cao JN, Gollapudi S, Sharman EH, Jia Z, Gupta S. Age-related alterations of gene expression patterns in human CD8+ T cells. Aging Cell. 2010 Feb; 9(1):19-31. PMID: 19878143.
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    48. Yel L, Ramanuja S, Gupta S. Clinical and immunological features in IgM deficiency. Int Arch Allergy Immunol. 2009; 150(3):291-8. PMID: 19494527.
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    49. Gupta S, Agrawal S, Gollapudi S. Differential effect of human herpesvirus 6A on cell division and apoptosis among naive and central and effector memory CD4+ and CD8+ T-cell subsets. J Virol. 2009 Jun; 83(11):5442-50. PMID: 19297473; PMCID: PMC2681935.
    50. Haider N, Arbustini E, Gupta S, Liu H, Narula N, Hajjar R, Moorjani N, Westaby S, Semigran MJ, Dec GW, Chandrashekhar Y, Narula J. Concurrent upregulation of endogenous proapoptotic and antiapoptotic factors in failing human hearts. Nat Clin Pract Cardiovasc Med. 2009 Mar; 6(3):250-61. PMID: 19234503.
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    51. Agrawal A, Tay J, Ton S, Agrawal S, Gupta S. Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA. J Immunol. 2009 Jan 15; 182(2):1138-45. PMID: 19124757; PMCID: PMC2621318.
    52. Gupta S. Immune homeostasis: regulatory T cells (Treg) and molecules. J Clin Immunol. 2008 Nov; 28(6):617-8. PMID: 18982430.
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    53. Agrawal S, Gupta S, Agrawal A. Vaccinia virus proteins activate human dendritic cells to induce T cell responses in vitro. Vaccine. 2009 Jan 01; 27(1):88-92. PMID: 18977270.
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    54. Young D, Popovic ZB, Jones WK, Gupta S. Blockade of NF-kappaB using IkappaB alpha dominant-negative mice ameliorates cardiac hypertrophy in myotrophin-overexpressed transgenic mice. J Mol Biol. 2008 Sep 05; 381(3):559-68. PMID: 18620706; PMCID: PMC2688722.
    55. Gupta S, Gollapudi S. CD95-mediated apoptosis in naïve, central and effector memory subsets of CD4+ and CD8+ T cells in aged humans. Exp Gerontol. 2008 Apr; 43(4):266-74. PMID: 18215485.
      View in: PubMed
    56. Sarai M, Hartung D, Petrov A, Zhou J, Narula N, Hofstra L, Kolodgie F, Isobe S, Fujimoto S, Vanderheyden JL, Virmani R, Reutelingsperger C, Wong ND, Gupta S, Narula J. Broad and specific caspase inhibitor-induced acute repression of apoptosis in atherosclerotic lesions evaluated by radiolabeled annexin A5 imaging. J Am Coll Cardiol. 2007 Dec 11; 50(24):2305-12. PMID: 18068039.
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    57. Gupta S, Young D, Maitra RK, Gupta A, Popovic ZB, Yong SL, Mahajan A, Wang Q, Sen S. Prevention of cardiac hypertrophy and heart failure by silencing of NF-kappaB. J Mol Biol. 2008 Jan 18; 375(3):637-49. PMID: 18037434; PMCID: PMC2277468.
    58. Agrawal A, Agrawal S, Tay J, Gupta S. Biology of dendritic cells in aging. J Clin Immunol. 2008 Jan; 28(1):14-20. PMID: 17828583.
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    59. Gupta S, Young T, Yel L, Su H, Gollapudi S. Differential sensitivity of naïve and subsets of memory CD4+ and CD8+ T cells to hydrogen peroxide-induced apoptosis. Genes Immun. 2007 Oct; 8(7):560-9. PMID: 17690685.
      View in: PubMed
    60. Gupta S, Gollapudi S. Effector memory CD8+ T cells are resistant to apoptosis. Ann N Y Acad Sci. 2007 Aug; 1109:145-50. PMID: 17785300.
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    61. Gupta S, Gupta AA. Death of memory T-cell subsets in humans: changes during aging. Expert Rev Clin Immunol. 2007 Jul; 3(4):637-45. PMID: 20477167.
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    62. Agrawal A, Agrawal S, Cao JN, Su H, Osann K, Gupta S. Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway. J Immunol. 2007 Jun 01; 178(11):6912-22. PMID: 17513740.
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    63. Young TY, Jerome D, Gupta S. Hyperimmunoglobulinemia E syndrome associated with coronary artery aneurysms: deficiency of central memory CD4+ T cells and expansion of effector memory CD4+ T cells. Ann Allergy Asthma Immunol. 2007 Apr; 98(4):389-92. PMID: 17458437.
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    64. Gupta S, Gollapudi S. Susceptibility of naïve and subsets of memory T cells to apoptosis via multiple signaling pathways. Autoimmun Rev. 2007 Aug; 6(7):476-81. PMID: 17643936.
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    65. Baysan A, Yel L, Gollapudi S, Su H, Gupta S. Arsenic trioxide induces apoptosis via the mitochondrial pathway by upregulating the expression of Bax and Bim in human B cells. Int J Oncol. 2007 Feb; 30(2):313-8. PMID: 17203211.
      View in: PubMed
    66. Agrawal A, Agrawal S, Gupta S. Dendritic cells in human aging. Exp Gerontol. 2007 May; 42(5):421-6. PMID: 17182207; PMCID: PMC1909691.
    67. Agrawal A, Kaushal P, Agrawal S, Gollapudi S, Gupta S. Thimerosal induces TH2 responses via influencing cytokine secretion by human dendritic cells. J Leukoc Biol. 2007 Feb; 81(2):474-82. PMID: 17079650.
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    68. Gupta S, Su H, Bi R, Gollapudi S. Differential sensitivity of naïve and memory subsets of human CD8+ T cells to TNF-alpha-induced apoptosis. J Clin Immunol. 2006 May; 26(3):193-203. PMID: 16783459.
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    69. Gupta S, Agrawal A, Agrawal S, Su H, Gollapudi S. A paradox of immunodeficiency and inflammation in human aging: lessons learned from apoptosis. Immun Ageing. 2006 May 19; 3:5. PMID: 16712718; PMCID: PMC1475884.
    70. Narula N, Gupta S, Narula J. The primary vasculitides: a clinicopathologic correlation. Am J Clin Pathol. 2005 Dec; 124 Suppl:S84-95. PMID: 16468419.
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    71. Yel L, Brown LE, Su K, Gollapudi S, Gupta S. Thimerosal induces neuronal cell apoptosis by causing cytochrome c and apoptosis-inducing factor release from mitochondria. Int J Mol Med. 2005 Dec; 16(6):971-7. PMID: 16273274.
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    72. Gupta S, Gollapudi S. TNF-alpha-induced apoptosis in human naïve and memory CD8+ T cells in aged humans. Exp Gerontol. 2006 Jan; 41(1):69-77. PMID: 16289923.
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    73. Gupta S, Gollapudi S. Molecular mechanisms of TNF-alpha-induced apoptosis in naïve and memory T cell subsets. Autoimmun Rev. 2006 Apr; 5(4):264-8. PMID: 16697967.
      View in: PubMed
    74. Gupta S, Su H, Bi R, Agrawal S, Gollapudi S. Life and death of lymphocytes: a role in immunesenescence. Immun Ageing. 2005 Aug 23; 2:12. PMID: 16115325; PMCID: PMC1236953.
    75. Gupta S, Sen S. Role of the NF-kappaB signaling cascade and NF-kappaB-targeted genes in failing human hearts. J Mol Med (Berl). 2005 Dec; 83(12):993-1004. PMID: 16133425.
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    76. Gupta S, Bi R, Gollapudi S. Central memory and effector memory subsets of human CD4(+) and CD8(+) T cells display differential sensitivity to TNF-{alpha}-induced apoptosis. Ann N Y Acad Sci. 2005 Jun; 1050:108-14. PMID: 16014525.
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    77. Gupta S. Molecular mechanisms of apoptosis in the cells of the immune system in human aging. Immunol Rev. 2005 Jun; 205:114-29. PMID: 15882349.
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    78. Gupta S, Reutelingsperger C, Narula J. Mortals turn me on... J Nucl Med. 2005 Jun; 46(6):906-8. PMID: 15937298.
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    79. Zhang Y, Da RR, Guo W, Ren HM, Hilgenberg LG, Sobel RA, Tourtellotte WW, Smith MA, Olek M, Gupta S, Robertson RT, Nagra R, Van Den Noort S, Qin Y. Axon reactive B cells clonally expanded in the cerebrospinal fluid of patients with multiple sclerosis. J Clin Immunol. 2005 May; 25(3):254-64. PMID: 15981091.
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    80. Gupta S, Gollapudi S. Molecular mechanisms of TNF-alpha-induced apoptosis in aging human T cell subsets. Int J Biochem Cell Biol. 2005 May; 37(5):1034-42. PMID: 15743676.
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    81. Gupta S, Young D, Sen S. Inhibition of NF-kappaB induces regression of cardiac hypertrophy, independent of blood pressure control, in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol. 2005 Jul; 289(1):H20-9. PMID: 15749748.
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    82. Gupta S, Bi R, Kim C, Chiplunkar S, Yel L, Gollapudi S. Role of NF-kappaB signaling pathway in increased tumor necrosis factor-alpha-induced apoptosis of lymphocytes in aged humans. Cell Death Differ. 2005 Feb; 12(2):177-83. PMID: 15647756.
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    83. Da RR, Kao G, Guo WZ, Olek M, Gupta S, Zhang Y, Van Den Noort S, Qin Y. Polyclonal B-cell expansion in the cerebrospinal fluid of patients with pseudotumor cerebri. J Clin Immunol. 2004 Nov; 24(6):674-82. PMID: 15622452.
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    84. Gupta S, Bi R, Su K, Yel L, Chiplunkar S, Gollapudi S. Characterization of naïve, memory and effector CD8+ T cells: effect of age. Exp Gerontol. 2004 Apr; 39(4):545-50. PMID: 15050289.
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    85. Sarkar S, Leaman DW, Gupta S, Sil P, Young D, Morehead A, Mukherjee D, Ratliff N, Sun Y, Rayborn M, Hollyfield J, Sen S. Cardiac overexpression of myotrophin triggers myocardial hypertrophy and heart failure in transgenic mice. J Biol Chem. 2004 May 07; 279(19):20422-34. PMID: 14970239.
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    86. Kim CH, Chiplunkar S, Gupta S. Chronic HIV type 1 infection down-regulates expression of DAP kinase and p19ARF-p53 checkpoint and is associated with resistance to CD95-mediated apoptosis in HUT78 T cells. AIDS Res Hum Retroviruses. 2004 Feb; 20(2):183-9. PMID: 15018706.
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    87. Gupta S. A role of inhibitor of apoptosis (IAP) proteins in increased lymphocyte apoptosis in aged humans. Mech Ageing Dev. 2004 Feb; 125(2):99-101. PMID: 15037009.
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    88. Gupta S, Kim C, Yel L, Gollapudi S. A role of fas-associated death domain (FADD) in increased apoptosis in aged humans. J Clin Immunol. 2004 Jan; 24(1):24-9. PMID: 14997030.
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    89. Yel L, Chen W, Gupta S. Cellular immunodeficiency and autoimmunity in long-term mineral oil administration. Ann Allergy Asthma Immunol. 2004 Jan; 92(1):88-91. PMID: 14756470.
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    90. Yel L, Liao O, Lin F, Gupta S. Severe T- and B-cell immune deficiency associated with malignant thymoma. Ann Allergy Asthma Immunol. 2003 Nov; 91(5):501-5. PMID: 14692437.
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    91. Gupta S, Yel L, Kim D, Kim C, Chiplunkar S, Gollapudi S. Arsenic trioxide induces apoptosis in peripheral blood T lymphocyte subsets by inducing oxidative stress: a role of Bcl-2. Mol Cancer Ther. 2003 Aug; 2(8):711-9. PMID: 12939460.
      View in: PubMed
    92. Gupta S, Chiplunkar S, Gupta A, Gollapudi S. Increased spontaneous, tumor necrosis factor receptor- and CD95 (Fas)-mediated apoptosis in cord blood T-cell subsets from Turner's syndrome. Genes Immun. 2003 Apr; 4(3):239-43. PMID: 12700600.
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    93. Gupta S, Chiplunkar S, Kim C, Yel L, Gollapudi S. Effect of age on molecular signaling of TNF-alpha-induced apoptosis in human lymphocytes. Mech Ageing Dev. 2003 Apr; 124(4):503-9. PMID: 12714259.
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    94. Gollapudi S, McCormick MJ, Gupta S. Changes in mitochondrial membrane potential and mitochondrial mass occur independent of the activation of caspase-8 and caspase-3 during CD95-mediated apoptosis in peripheral blood T cells. Int J Oncol. 2003 Mar; 22(3):597-600. PMID: 12579313.
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    95. Gollapudi S, Jaidka S, Gupta S. Molecular basis of rifampicin-induced inhibition of anti-CD95-induced apoptosis of peripheral blood T lymphocytes: the role of CD95 ligand and FLIPs. J Clin Immunol. 2003 Jan; 23(1):11-22. PMID: 12645856.
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    96. Gupta S. Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review). Int J Oncol. 2003 Jan; 22(1):15-20. PMID: 12469180.
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    97. Gupta S, Purcell NH, Lin A, Sen S. Activation of nuclear factor-kappaB is necessary for myotrophin-induced cardiac hypertrophy. J Cell Biol. 2002 Dec 23; 159(6):1019-28. PMID: 12486112; PMCID: PMC2173971.
    98. Gupta S. A decision between life and death during TNF-alpha-induced signaling. J Clin Immunol. 2002 Jul; 22(4):185-94. PMID: 12148593.
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    99. Gupta S, Sen S. Myotrophin-kappaB DNA interaction in the initiation process of cardiac hypertrophy. Biochim Biophys Acta. 2002 May 08; 1589(3):247-60. PMID: 12031792.
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    100. Gupta S. Tumor necrosis factor-alpha-induced apoptosis in T cells from aged humans: a role of TNFR-I and downstream signaling molecules. Exp Gerontol. 2002 Jan-Mar; 37(2-3):293-9. PMID: 11772515.
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    101. Yerramasetti R, Gollapudi S, Gupta S. Rifampicin inhibits CD95-mediated apoptosis of Jurkat T cells via glucocorticoid receptors by modifying the expression of molecules regulating apoptosis. J Clin Immunol. 2002 Jan; 22(1):37-47. PMID: 11958592.
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    102. Gupta S. Molecular steps of tumor necrosis factor receptor-mediated apoptosis. Curr Mol Med. 2001 Jul; 1(3):317-24. PMID: 11899080.
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    103. Gupta S. Immunological treatments for autism. J Autism Dev Disord. 2000 Oct; 30(5):475-9. PMID: 11098887.
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