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Timothy L. Downing

TitleAssistant Professor
InstitutionUniversity of California, Irvine
DepartmentBiomedical Engineering
Address2408 Engineering III
Zot 2730
Irvine CA 92697
Phone(949) 824-8744
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Charlton J, Downing TL, Smith ZD, Gu H, Clement K, Pop R, Akopian V, Klages S, Santos DP, Tsankov AM, Timmermann B, Ziller MJ, Kiskinis E, Gnirke A, Meissner A. Author Correction: Global delay in nascent strand DNA methylation. Nat Struct Mol Biol. 2018 Apr; 25(4):355. PMID: 29581568.
      View in: PubMed
    2. Charlton J, Downing TL, Smith ZD, Gu H, Clement K, Pop R, Akopian V, Klages S, Santos DP, Tsankov AM, Timmermann B, Ziller MJ, Kiskinis E, Gnirke A, Meissner A. Global delay in nascent strand DNA methylation. Nat Struct Mol Biol. 2018 Apr; 25(4):327-332. PMID: 29531288.
      View in: PubMed
    3. Liu L, Zhang SX, Liao W, Farhoodi HP, Wong CW, Chen CC, S├ęgaliny AI, Chacko JV, Nguyen LP, Lu M, Polovin G, Pone EJ, Downing TL, Lawson DA, Digman MA, Zhao W. Mechanoresponsive stem cells to target cancer metastases through biophysical cues. Sci Transl Med. 2017 Jul 26; 9(400). PMID: 28747514.
      View in: PubMed
    4. Downing TL, Soto J, Morez C, Houssin T, Fritz A, Yuan F, Chu J, Patel S, Schaffer DV, Li S. Biophysical regulation of epigenetic state and cell reprogramming. Nat Mater. 2013 Dec; 12(12):1154-62. PMID: 24141451.
      View in: PubMed
    5. Saadai P, Wang A, Nout YS, Downing TL, Lofberg K, Beattie MS, Bresnahan JC, Li S, Farmer DL. Human induced pluripotent stem cell-derived neural crest stem cells integrate into the injured spinal cord in the fetal lamb model of myelomeningocele. J Pediatr Surg. 2013 Jan; 48(1):158-63. PMID: 23331809.
      View in: PubMed
    6. Downing TL, Wang A, Yan ZQ, Nout Y, Lee AL, Beattie MS, Bresnahan JC, Farmer DL, Li S. Drug-eluting microfibrous patches for the local delivery of rolipram in spinal cord repair. J Control Release. 2012 Aug 10; 161(3):910-7. PMID: 22634093; PMCID: PMC3698241.
    7. Saadai P, Nout YS, Encinas J, Wang A, Downing TL, Beattie MS, Bresnahan JC, Li S, Farmer DL. Prenatal repair of myelomeningocele with aligned nanofibrous scaffolds-a pilot study in sheep. J Pediatr Surg. 2011 Dec; 46(12):2279-83. PMID: 22152865.
      View in: PubMed