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William E Karnes

Title(s)Health Sciences Professor, Medicine
Phone(714) 456-6745
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    Collapse Research Activities and Funding
    BETA-CATENIN AND RAR INTERACT AT THE PKC ALPHA PROMOTER
    NIH/NIDDK R01DK056378Aug 1, 1999 - Jul 31, 2004
    Role: Co-Principal Investigator
    PKC--MEDIATED GROWTH AND APOPTOSIS
    NIH/NCI R29CA071974Sep 30, 1996 - Sep 29, 2001
    Role: Principal Investigator
    MECHANISMS OF LIGAND-INDEPENDENT TRANSFORMATION BY C-ERB
    NIH/NCI K11CA001674Sep 1, 1992 - Aug 31, 1997
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hashimoto R, Requa J, Tyler D, Ninh A, Tran E, Mai D, Lugo M, El-Hage Chehade N, Chang KJ, Karnes WE, Samarasena J. Artificial intelligence using convolutional neural networks for real-time detection of early esophageal neoplasia in Barrett's esophagus (with video). Gastrointest Endosc. 2020 Jan 10. PMID: 31930967.
      View in: PubMed
    2. Zachariah R, Samarasena J, Luba D, Duh E, Dao T, Requa J, Ninh A, Karnes W. Prediction of Polyp Pathology Using Convolutional Neural Networks Achieves "Resect and Discard" Thresholds. Am J Gastroenterol. 2020 Jan; 115(1):138-144. PMID: 31651444.
      View in: PubMed
    3. Urban G, Tripathi P, Alkayali T, Mittal M, Jalali F, Karnes W, Baldi P. Deep Learning Localizes and Identifies Polyps in Real Time With 96% Accuracy in Screening Colonoscopy. Gastroenterology. 2018 10; 155(4):1069-1078.e8. PMID: 29928897.
      View in: PubMed
    4. Chin M, Karnes W, Jamal MM, Lee JG, Lee R, Samarasena J, Bechtold ML, Nguyen DL. Use of the Endocuff during routine colonoscopy examination improves adenoma detection: A meta-analysis. World J Gastroenterol. 2016 Nov 21; 22(43):9642-9649. PMID: 27920485.
      View in: PubMed
    5. Tsang WY, Ziogas A, Lin BS, Seery TE, Karnes W, Stamos MJ, Zell JA. Role of primary tumor resection among chemotherapy-treated patients with synchronous stage IV colorectal cancer: a survival analysis. J Gastrointest Surg. 2014 Mar; 18(3):592-8. PMID: 24297651.
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    6. Weller SG, Klein IK, Penington RC, Karnes WE. Distinct protein kinase C isozymes signal mitogenesis and apoptosis in human colon cancer cells. Gastroenterology. 1999 Oct; 117(4):848-57. PMID: 10500067.
      View in: PubMed
    7. Karnes WE, Shattuck-Brandt R, Burgart LJ, DuBois RN, Tester DJ, Cunningham JM, Kim CY, McDonnell SK, Schaid DJ, Thibodeau SN. Reduced COX-2 protein in colorectal cancer with defective mismatch repair. Cancer Res. 1998 Dec 01; 58(23):5473-7. PMID: 9850081.
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    8. Karnes WE, Weller SG, Adjei PN, Kottke TJ, Glenn KS, Gores GJ, Kaufmann SH. Inhibition of epidermal growth factor receptor kinase induces protease-dependent apoptosis in human colon cancer cells. Gastroenterology. 1998 May; 114(5):930-9. PMID: 9558281.
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    9. Boardman LA, Karnes WE. Src family of tyrosine kinases: a role of c-yes in colon carcinogenesis? Gastroenterology. 1995 Jan; 108(1):291-4. PMID: 7806054.
      View in: PubMed
    10. Karnes WE, Walsh JH, Wu SV, Kim RS, Martin MG, Wong HC, Mendelsohn J, Park JG, Cuttitta F. Autonomous proliferation of colon cancer cells that coexpress transforming growth factor alpha and its receptor. Variable effects of receptor-blocking antibody. Gastroenterology. 1992 Feb; 102(2):474-85. PMID: 1732118.
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    11. Goldschmiedt M, Barnett CC, Schwarz BE, Karnes WE, Redfern JS, Feldman M. Effect of age on gastric acid secretion and serum gastrin concentrations in healthy men and women. Gastroenterology. 1991 Oct; 101(4):977-90. PMID: 1889722.
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    12. Karnes WE, Samloff IM, Siurala M, Kekki M, Sipponen P, Kim SW, Walsh JH. Positive serum antibody and negative tissue staining for Helicobacter pylori in subjects with atrophic body gastritis. Gastroenterology. 1991 Jul; 101(1):167-74. PMID: 2044906.
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