Zaragoza, Michael Vincent

Title(s)Associate Professor, Pediatrics
Phone(949) 824-8813
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    Collapse Research Activities and Funding
    Cardiac Functional and Structural Implications of Lamin A/C Mutations
    NIH/NHLBI R01HL129008Sep 4, 2015 - Apr 30, 2020
    Role: Co-Principal Investigator
    Mitochondrial Dysfunction &Noncompaction Cardiomyopathy
    NIH/NHLBI K08HL081222Sep 29, 2006 - Sep 30, 2011
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Core JQ, Mehrabi M, Robinson ZR, Ochs AR, McCarthy LA, Zaragoza MV, Grosberg A. Age of heart disease presentation and dysmorphic nuclei in patients with LMNA mutations. PLoS One. 2017; 12(11):e0188256. PMID: 29149195.
      View in: PubMed
    2. Zaragoza MV, Nguyen CHH, Widyastuti HP, McCarthy LA, Grosberg A. Dupuytren's and Ledderhose Diseases in a Family with LMNA-Related Cardiomyopathy and a Novel Variant in the ASTE1 Gene. Cells. 2017 Nov 01; 6(4). PMID: 29104234.
      View in: PubMed
    3. Zaragoza MV, Fung L, Jensen E, Oh F, Cung K, McCarthy LA, Tran CK, Hoang V, Hakim SA, Grosberg A. Exome Sequencing Identifies a Novel LMNA Splice-Site Mutation and Multigenic Heterozygosity of Potential Modifiers in a Family with Sick Sinus Syndrome, Dilated Cardiomyopathy, and Sudden Cardiac Death. PLoS One. 2016; 11(5):e0155421. PMID: 27182706.
      View in: PubMed
    4. Marshall LS, Simon J, Wood T, Peng M, Owen R, Feldman GS, Zaragoza MV. Deletion Xq27.3q28 in female patient with global developmental delays and skewed X-inactivation. BMC Med Genet. 2013 May 01; 14:49. PMID: 23634718; PMCID: PMC3643848.
    5. Strauss KA, DuBiner L, Simon M, Zaragoza M, Sengupta PP, Li P, Narula N, Dreike S, Platt J, Procaccio V, Ortiz-González XR, Puffenberger EG, Kelley RI, Morton DH, Narula J, Wallace DC. Severity of cardiomyopathy associated with adenine nucleotide translocator-1 deficiency correlates with mtDNA haplogroup. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3453-8. PMID: 23401503; PMCID: PMC3587196.
    6. Ronvelia D, Greenwood J, Platt J, Hakim S, Zaragoza MV. Intrafamilial variability for novel TAZ gene mutation: Barth syndrome with dilated cardiomyopathy and heart failure in an infant and left ventricular noncompaction in his great-uncle. Mol Genet Metab. 2012 Nov; 107(3):428-32. PMID: 23031367; PMCID: PMC3483384.
    7. Narula N, Zaragoza MV, Sengupta PP, Li P, Haider N, Verjans J, Waymire K, Vannan M, Wallace DC. Adenine nucleotide translocase 1 deficiency results in dilated cardiomyopathy with defects in myocardial mechanics, histopathological alterations, and activation of apoptosis. JACC Cardiovasc Imaging. 2011 Jan; 4(1):1-10. PMID: 21232697; PMCID: PMC4023693.
    8. Zaragoza MV, Brandon MC, Diegoli M, Arbustini E, Wallace DC. Mitochondrial cardiomyopathies: how to identify candidate pathogenic mutations by mitochondrial DNA sequencing, MITOMASTER and phylogeny. Eur J Hum Genet. 2011 Feb; 19(2):200-7. PMID: 20978534; PMCID: PMC3025796.
    9. Zaragoza MV, Fass J, Diegoli M, Lin D, Arbustini E. Mitochondrial DNA variant discovery and evaluation in human Cardiomyopathies through next-generation sequencing. PLoS One. 2010 Aug 20; 5(8):e12295. PMID: 20808834; PMCID: PMC2924892.
    10. Lindvall LE, Kormeili T, Chen E, Ramirez MC, Grum-Tokars V, Glucksman MJ, Martignetti JA, Zaragoza MV, Dyson SW. Infantile systemic hyalinosis: Case report and review of the literature. J Am Acad Dermatol. 2008 Feb; 58(2):303-7. PMID: 18222328.
      View in: PubMed
    11. Zaragoza MV, Arbustini E, Narula J. Noncompaction of the left ventricle: primary cardiomyopathy with an elusive genetic etiology. Curr Opin Pediatr. 2007 Dec; 19(6):619-27. PMID: 18025927.
      View in: PubMed
    12. Pop R, Zaragoza MV, Gaudette M, Dohrmann U, Scherer G. A homozygous nonsense mutation in SOX9 in the dominant disorder campomelic dysplasia: a case of mitotic gene conversion. Hum Genet. 2005 Jun; 117(1):43-53. PMID: 15806394.
      View in: PubMed
    13. Zaragoza MV, Lewis LE, Sun G, Wang E, Li L, Said-Salman I, Feucht L, Huang T. Identification of the TBX5 transactivating domain and the nuclear localization signal. Gene. 2004 Apr 14; 330:9-18. PMID: 15087119.
      View in: PubMed