Cho, Ken Won-Young

InstitutionUniversity of California, Irvine
DepartmentDevelopmental & Cell Biology
Address4400 Natural Sciences II
Zot 2300
CA 92697
Phone(949) 824-7950, 4067
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Charney RM, Paraiso KD, Blitz IL, Cho K. A gene regulatory program controlling early Xenopus mesendoderm formation: Network conservation and motifs. Semin Cell Dev Biol. 2017 06; 66:12-24. PMID: 28341363.
      View in: PubMed
    2. Charney RM, Forouzmand E, Cho JS, Cheung J, Paraiso KD, Yasuoka Y, Takahashi S, Taira M, Blitz IL, Xie X, Cho K. Foxh1 Occupies cis-Regulatory Modules Prior to Dynamic Transcription Factor Interactions Controlling the Mesendoderm Gene Program. Dev Cell. 2017 03 27; 40(6):595-607.e4. PMID: 28325473.
      View in: PubMed
    3. Blitz IL, Paraiso KD, Patrushev I, Chiu WTY, Cho K, Gilchrist MJ. A catalog of Xenopus tropicalis transcription factors and their regional expression in the early gastrula stage embryo. Dev Biol. 2017 06 15; 426(2):409-417. PMID: 27475627.
      View in: PubMed
    4. Forouzmand E, Owens NDL, Blitz IL, Paraiso KD, Khokha MK, Gilchrist MJ, Xie X, Cho K. Developmentally regulated long non-coding RNAs in Xenopus tropicalis. Dev Biol. 2017 06 15; 426(2):401-408. PMID: 27418388.
      View in: PubMed
    5. Blitz IL, Fish MB, Cho K. Leapfrogging: primordial germ cell transplantation permits recovery of CRISPR/Cas9-induced mutations in essential genes. Development. 2016 08 01; 143(15):2868-75. PMID: 27385011; PMCID: PMC5004912 [Available on 08/01/17].
    6. Owens NDL, Blitz IL, Lane MA, Patrushev I, Overton JD, Gilchrist MJ, Cho K, Khokha MK. Measuring Absolute RNA Copy Numbers at High Temporal Resolution Reveals Transcriptome Kinetics in Development. Cell Rep. 2016 Jan 26; 14(3):632-647. PMID: 26774488; PMCID: PMC4731879.
    7. Chiang M, Hallman S, Cinquin A, de Mochel NR, Paz A, Kawauchi S, Calof AL, Cho K, Fowlkes CC, Cinquin O. Analysis of in vivo single cell behavior by high throughput, human-in-the-loop segmentation of three-dimensional images. BMC Bioinformatics. 2015 Nov 25; 16:397. PMID: 26607933; PMCID: PMC4659165.
    8. Wang X, Hsi TC, Guerrero-Juarez CF, Pham K, Cho K, McCusker CD, Monuki ES, Cho K, Gay DL, Plikus MV. Principles and mechanisms of regeneration in the mouse model for wound-induced hair follicle neogenesis. Regeneration (Oxf). 2015 Aug; 2(4):169-181. PMID: 26504521.
      View in: PubMed
    9. Chiu WT, Charney Le R, Blitz IL, Fish MB, Li Y, Biesinger J, Xie X, Cho K. Genome-wide view of TGFß/Foxh1 regulation of the early mesendoderm program. Development. 2014 Dec; 141(23):4537-47. PMID: 25359723; PMCID: PMC4302925.
    10. Reyes de Mochel NS, Luong M, Chiang M, Javier AL, Luu E, Toshihiko F, MacGregor GR, Cinquin O, Cho K. BMP signaling is required for cell cleavage in preimplantation-mouse embryos. Dev Biol. 2015 Jan 01; 397(1):45-55. PMID: 25446538; PMCID: PMC4309750.
    11. Yang G, Yuan G, Ye W, Cho K, Chen Y. An atypical canonical bone morphogenetic protein (BMP) signaling pathway regulates Msh homeobox 1 (Msx1) expression during odontogenesis. J Biol Chem. 2014 Nov 07; 289(45):31492-502. PMID: 25274628; PMCID: PMC4223347.
    12. Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho K, Asashima M, Sugano S, Taira M. Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification. Nat Commun. 2014 Jul 09; 5:4322. PMID: 25005894; PMCID: PMC4805429.
    13. Zheng Z, Christley S, Chiu WT, Blitz IL, Xie X, Cho K, Nie Q. Inference of the Xenopus tropicalis embryonic regulatory network and spatial gene expression patterns. BMC Syst Biol. 2014 Jan 08; 8:3. PMID: 24397936; PMCID: PMC3896677.
    14. Nakayama T, Blitz IL, Fish MB, Odeleye AO, Manohar S, Cho K, Grainger RM. Cas9-based genome editing in Xenopus tropicalis. Methods Enzymol. 2014; 546:355-75. PMID: 25398349; PMCID: PMC4284096.
    15. Blitz IL, Biesinger J, Xie X, Cho K. Biallelic genome modification in F(0) Xenopus tropicalis embryos using the CRISPR/Cas system. Genesis. 2013 Dec; 51(12):827-34. PMID: 24123579; PMCID: PMC4039559.
    16. Javier AL, Doan LT, Luong M, Reyes de Mochel NS, Sun A, Monuki ES, Cho K. Bmp indicator mice reveal dynamic regulation of transcriptional response. PLoS One. 2012; 7(9):e42566. PMID: 22984405; PMCID: PMC3439458.
    17. Doan LT, Javier AL, Furr NM, Nguyen KL, Cho K, Monuki ES. A Bmp reporter with ultrasensitive characteristics reveals that high Bmp signaling is not required for cortical hem fate. PLoS One. 2012; 7(9):e44009. PMID: 22984456; PMCID: PMC3439469.
    18. Cho K. Enhancers. Wiley Interdiscip Rev Dev Biol. 2012 Jul-Aug; 1(4):469-78. PMID: 23801531; PMCID: PMC3979590.
    19. Alexander C, Zuniga E, Blitz IL, Wada N, Le Pabic P, Javidan Y, Zhang T, Cho K, Crump JG, Schilling TF. Combinatorial roles for BMPs and Endothelin 1 in patterning the dorsal-ventral axis of the craniofacial skeleton. Development. 2011 Dec; 138(23):5135-46. PMID: 22031543; PMCID: PMC3210495.
    20. Onai T, Yu JK, Blitz IL, Cho K, Holland LZ. Opposing Nodal/Vg1 and BMP signals mediate axial patterning in embryos of the basal chordate amphioxus. Dev Biol. 2010 Aug 01; 344(1):377-89. PMID: 20488174; PMCID: PMC4781670.
    21. Blitz IL, Cho K. Finding partners: how BMPs select their targets. Dev Dyn. 2009 Jun; 238(6):1321-31. PMID: 19441058.
      View in: PubMed
    22. Hayata T, Blitz IL, Iwata N, Cho K. Identification of embryonic pancreatic genes using Xenopus DNA microarrays. Dev Dyn. 2009 Jun; 238(6):1455-66. PMID: 19191222; PMCID: PMC4203858.
    23. Karaulanov E, Böttcher RT, Stannek P, Wu W, Rau M, Ogata S, Cho K, Niehrs C. Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryos. PLoS One. 2009 May 29; 4(5):e5742. PMID: 19492039; PMCID: PMC2683942.
    24. Jarikji Z, Horb LD, Shariff F, Mandato CA, Cho K, Horb ME. The tetraspanin Tm4sf3 is localized to the ventral pancreas and regulates fusion of the dorsal and ventral pancreatic buds. Development. 2009 Jun; 136(11):1791-800. PMID: 19403659; PMCID: PMC2680106.
    25. Maretto S, Müller PS, Aricescu AR, Cho K, Bikoff EK, Robertson EJ. Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3. Dev Biol. 2008 Jun 01; 318(1):184-93. PMID: 18448090.
      View in: PubMed
    26. Ogata S, Morokuma J, Hayata T, Kolle G, Niehrs C, Ueno N, Cho K. TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis. Genes Dev. 2007 Jul 15; 21(14):1817-31. PMID: 17639085; PMCID: PMC1920175.
    27. Park EC, Hayata T, Cho K, Han JK. Xenopus cDNA microarray identification of genes with endodermal organ expression. Dev Dyn. 2007 Jun; 236(6):1633-49. PMID: 17474120.
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    28. Ogata S, Cho K. Dissection of organizer and animal pole explants from Xenopus laevis embryos and assembly of a cell adhesion assay. J Vis Exp. 2007; (3):187. PMID: 18978993; PMCID: PMC2535839.
    29. Ogata S, Kawauchi S, Calof A, Cho K. Plastic embedding and sectioning of Xenopus laevis embryos. J Vis Exp. 2007; (3):188. PMID: 18978994; PMCID: PMC2535840.
    30. Suzawa K, Yukita A, Hayata T, Goto T, Danno H, Michiue T, Cho K, Asashima M. Xenopus glucose transporter 1 (xGLUT1) is required for gastrulation movement in Xenopus laevis. Int J Dev Biol. 2007; 51(3):183-90. PMID: 17486538.
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    31. Li S, Shin Y, Cho K, Merzdorf CS. The Xfeb gene is directly upregulated by Zic1 during early neural development. Dev Dyn. 2006 Oct; 235(10):2817-27. PMID: 16871635.
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    32. Yao LC, Blitz IL, Peiffer DA, Phin S, Wang Y, Ogata S, Cho K, Arora K, Warrior R. Schnurri transcription factors from Drosophila and vertebrates can mediate Bmp signaling through a phylogenetically conserved mechanism. Development. 2006 Oct; 133(20):4025-34. PMID: 17008448.
      View in: PubMed
    33. Koide T, Hayata T, Cho K. Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase. Development. 2006 Jun; 133(12):2395-405. PMID: 16687448.
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    34. Chalmers AD, Lachani K, Shin Y, Sherwood V, Cho K, Papalopulu N. Grainyhead-like 3, a transcription factor identified in a microarray screen, promotes the specification of the superficial layer of the embryonic epidermis. Mech Dev. 2006 Sep; 123(9):702-18. PMID: 16916602.
      View in: PubMed
    35. Murato Y, Yamaguti M, Katamura M, Cho K, Hashimoto C. Two modes of action by which Xenopus hairy2b establishes tissue demarcation in the Spemann-Mangold organizer. Int J Dev Biol. 2006; 50(5):463-71. PMID: 16586347.
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    36. Yamaguti M, Cho K, Hashimoto C. Xenopus hairy2b specifies anterior prechordal mesoderm identity within Spemann's organizer. Dev Dyn. 2005 Sep; 234(1):102-13. PMID: 16059909.
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    37. Luo T, Zhang Y, Khadka D, Rangarajan J, Cho K, Sargent TD. Regulatory targets for transcription factor AP2 in Xenopus embryos. Dev Growth Differ. 2005 Aug; 47(6):403-13. PMID: 16109038.
      View in: PubMed
    38. von Bubnoff A, Peiffer DA, Blitz IL, Hayata T, Ogata S, Zeng Q, Trunnell M, Cho K. Phylogenetic footprinting and genome scanning identify vertebrate BMP response elements and new target genes. Dev Biol. 2005 May 15; 281(2):210-26. PMID: 15893974.
      View in: PubMed
    39. Koide T, Hayata T, Cho K. Xenopus as a model system to study transcriptional regulatory networks. Proc Natl Acad Sci U S A. 2005 Apr 05; 102(14):4943-8. PMID: 15795378; PMCID: PMC555977.
    40. Taverner NV, Kofron M, Shin Y, Kabitschke C, Gilchrist MJ, Wylie C, Cho K, Heasman J, Smith JC. Microarray-based identification of VegT targets in Xenopus. Mech Dev. 2005 Mar; 122(3):333-54. PMID: 15763211.
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    41. Baldessari D, Shin Y, Krebs O, König R, Koide T, Vinayagam A, Fenger U, Mochii M, Terasaka C, Kitayama A, Peiffer D, Ueno N, Eils R, Cho K, Niehrs C. Global gene expression profiling and cluster analysis in Xenopus laevis. Mech Dev. 2005 Mar; 122(3):441-75. PMID: 15763214.
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    42. Shin Y, Kitayama A, Koide T, Peiffer DA, Mochii M, Liao A, Ueno N, Cho K. Identification of neural genes using Xenopus DNA microarrays. Dev Dyn. 2005 Feb; 232(2):432-44. PMID: 15614765.
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    43. Arima K, Shiotsugu J, Niu R, Khandpur R, Martinez M, Shin Y, Koide T, Cho K, Kitayama A, Ueno N, Chandraratna RA, Blumberg B. Global analysis of RAR-responsive genes in the Xenopus neurula using cDNA microarrays. Dev Dyn. 2005 Feb; 232(2):414-31. PMID: 15614783.
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    44. Peiffer DA, Von Bubnoff A, Shin Y, Kitayama A, Mochii M, Ueno N, Cho K. A Xenopus DNA microarray approach to identify novel direct BMP target genes involved in early embryonic development. Dev Dyn. 2005 Feb; 232(2):445-56. PMID: 15614776.
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    45. Meek LM, Hayata T, Shin YC, Evinger AJ, Cho K. Cloning and expression of an SH3 domain-containing protein (Xchef-1), a novel downstream target of activin/nodal signaling. Gene Expr Patterns. 2004 Oct; 4(6):719-24. PMID: 15465495.
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    46. Blitz IL, Cho K, Chang C. Twisted gastrulation loss-of-function analyses support its role as a BMP inhibitor during early Xenopus embryogenesis. Development. 2003 Oct; 130(20):4975-88. PMID: 12952901.
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    47. Tsuji S, Cho K, Hashimoto C. Expression pattern of a basic helix-loop-helix transcription factor Xhairy2b during Xenopus laevis development. Dev Genes Evol. 2003 Aug; 213(8):407-11. PMID: 12774230.
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    48. Yoshida Y, von Bubnoff A, Ikematsu N, Blitz IL, Tsuzuku JK, Yoshida EH, Umemori H, Miyazono K, Yamamoto T, Cho K. Tob proteins enhance inhibitory Smad-receptor interactions to repress BMP signaling. Mech Dev. 2003 May; 120(5):629-37. PMID: 12782279.
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    49. Hashimoto-Partyka MK, Yuge M, Cho K. Nodal signaling in Xenopus gastrulae is cell-autonomous and patterned by beta-catenin. Dev Biol. 2003 Jan 01; 253(1):125-38. PMID: 12490202.
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    50. Tran PH, Peiffer DA, Shin Y, Meek LM, Brody JP, Cho K. Microarray optimizations: increasing spot accuracy and automated identification of true microarray signals. Nucleic Acids Res. 2002 Jun 15; 30(12):e54. PMID: 12060692; PMCID: PMC117296.
    51. Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho K. The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling. Genes Dev. 2002 Apr 01; 16(7):820-35. PMID: 11937490; PMCID: PMC186325.
    52. Cho K, Blitz IL. BMPs, Smads and metalloproteases: extracellular and intracellular modes of negative regulation. Curr Opin Genet Dev. 1998 Aug; 8(4):443-9. PMID: 9729721.
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