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Cho, Ken Won-Young

TitleProfessor
InstitutionUniversity of California, Irvine
DepartmentDevelopmental & Cell Biology
Address4400 Natural Sciences II
Zot 2300
Irvine CA 92697
Phone(949) 824-7950, 4067
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Cho JS, Blitz IL, Cho KWY. DNase-seq to Study Chromatin Accessibility in Early Xenopus tropicalis Embryos. Cold Spring Harb Protoc. 2018 Aug 21. PMID: 30131367.
      View in: PubMed
    2. Charney RM, Paraiso KD, Blitz IL, Cho KWY. A gene regulatory program controlling early Xenopus mesendoderm formation: Network conservation and motifs. Semin Cell Dev Biol. 2017 06; 66:12-24. PMID: 28341363.
      View in: PubMed
    3. Charney RM, Forouzmand E, Cho JS, Cheung J, Paraiso KD, Yasuoka Y, Takahashi S, Taira M, Blitz IL, Xie X, Cho KW. Foxh1 Occupies cis-Regulatory Modules Prior to Dynamic Transcription Factor Interactions Controlling the Mesendoderm Gene Program. Dev Cell. 2017 03 27; 40(6):595-607.e4. PMID: 28325473.
      View in: PubMed
    4. Blitz IL, Paraiso KD, Patrushev I, Chiu WTY, Cho KWY, Gilchrist MJ. A catalog of Xenopus tropicalis transcription factors and their regional expression in the early gastrula stage embryo. Dev Biol. 2017 06 15; 426(2):409-417. PMID: 27475627.
      View in: PubMed
    5. Forouzmand E, Owens NDL, Blitz IL, Paraiso KD, Khokha MK, Gilchrist MJ, Xie X, Cho KWY. Developmentally regulated long non-coding RNAs in Xenopus tropicalis. Dev Biol. 2017 06 15; 426(2):401-408. PMID: 27418388.
      View in: PubMed
    6. Blitz IL, Fish MB, Cho KW. Leapfrogging: primordial germ cell transplantation permits recovery of CRISPR/Cas9-induced mutations in essential genes. Development. 2016 08 01; 143(15):2868-75. PMID: 27385011; PMCID: PMC5004912 [Available on 08/01/17].
    7. Owens NDL, Blitz IL, Lane MA, Patrushev I, Overton JD, Gilchrist MJ, Cho KWY, Khokha MK. Measuring Absolute RNA Copy Numbers at High Temporal Resolution Reveals Transcriptome Kinetics in Development. Cell Rep. 2016 Jan 26; 14(3):632-647. PMID: 26774488; PMCID: PMC4731879.
    8. Chiang M, Hallman S, Cinquin A, de Mochel NR, Paz A, Kawauchi S, Calof AL, Cho KW, Fowlkes CC, Cinquin O. Analysis of in vivo single cell behavior by high throughput, human-in-the-loop segmentation of three-dimensional images. BMC Bioinformatics. 2015 Nov 25; 16:397. PMID: 26607933; PMCID: PMC4659165.
    9. Wang X, Hsi TC, Guerrero-Juarez CF, Pham K, Cho K, McCusker CD, Monuki ES, Cho KW, Gay DL, Plikus MV. Principles and mechanisms of regeneration in the mouse model for wound-induced hair follicle neogenesis. Regeneration (Oxf). 2015 Aug; 2(4):169-181. PMID: 26504521.
      View in: PubMed
    10. Chiu WT, Charney Le R, Blitz IL, Fish MB, Li Y, Biesinger J, Xie X, Cho KW. Genome-wide view of TGFß/Foxh1 regulation of the early mesendoderm program. Development. 2014 Dec; 141(23):4537-47. PMID: 25359723; PMCID: PMC4302925.
    11. Reyes de Mochel NS, Luong M, Chiang M, Javier AL, Luu E, Toshihiko F, MacGregor GR, Cinquin O, Cho KW. BMP signaling is required for cell cleavage in preimplantation-mouse embryos. Dev Biol. 2015 Jan 01; 397(1):45-55. PMID: 25446538; PMCID: PMC4309750.
    12. Yang G, Yuan G, Ye W, Cho KW, Chen Y. An atypical canonical bone morphogenetic protein (BMP) signaling pathway regulates Msh homeobox 1 (Msx1) expression during odontogenesis. J Biol Chem. 2014 Nov 07; 289(45):31492-502. PMID: 25274628; PMCID: PMC4223347.
    13. Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M. Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification. Nat Commun. 2014 Jul 09; 5:4322. PMID: 25005894; PMCID: PMC4805429.
    14. Zheng Z, Christley S, Chiu WT, Blitz IL, Xie X, Cho KW, Nie Q. Inference of the Xenopus tropicalis embryonic regulatory network and spatial gene expression patterns. BMC Syst Biol. 2014 Jan 08; 8:3. PMID: 24397936; PMCID: PMC3896677.
    15. Nakayama T, Blitz IL, Fish MB, Odeleye AO, Manohar S, Cho KW, Grainger RM. Cas9-based genome editing in Xenopus tropicalis. Methods Enzymol. 2014; 546:355-75. PMID: 25398349; PMCID: PMC4284096.
    16. Blitz IL, Biesinger J, Xie X, Cho KW. Biallelic genome modification in F(0) Xenopus tropicalis embryos using the CRISPR/Cas system. Genesis. 2013 Dec; 51(12):827-34. PMID: 24123579; PMCID: PMC4039559.
    17. Javier AL, Doan LT, Luong M, Reyes de Mochel NS, Sun A, Monuki ES, Cho KW. Bmp indicator mice reveal dynamic regulation of transcriptional response. PLoS One. 2012; 7(9):e42566. PMID: 22984405; PMCID: PMC3439458.
    18. Doan LT, Javier AL, Furr NM, Nguyen KL, Cho KW, Monuki ES. A Bmp reporter with ultrasensitive characteristics reveals that high Bmp signaling is not required for cortical hem fate. PLoS One. 2012; 7(9):e44009. PMID: 22984456; PMCID: PMC3439469.
    19. Cho KW. Enhancers. Wiley Interdiscip Rev Dev Biol. 2012 Jul-Aug; 1(4):469-78. PMID: 23801531; PMCID: PMC3979590.
    20. Alexander C, Zuniga E, Blitz IL, Wada N, Le Pabic P, Javidan Y, Zhang T, Cho KW, Crump JG, Schilling TF. Combinatorial roles for BMPs and Endothelin 1 in patterning the dorsal-ventral axis of the craniofacial skeleton. Development. 2011 Dec; 138(23):5135-46. PMID: 22031543; PMCID: PMC3210495.
    21. Onai T, Yu JK, Blitz IL, Cho KW, Holland LZ. Opposing Nodal/Vg1 and BMP signals mediate axial patterning in embryos of the basal chordate amphioxus. Dev Biol. 2010 Aug 01; 344(1):377-89. PMID: 20488174; PMCID: PMC4781670.
    22. Blitz IL, Cho KW. Finding partners: how BMPs select their targets. Dev Dyn. 2009 Jun; 238(6):1321-31. PMID: 19441058.
      View in: PubMed
    23. Hayata T, Blitz IL, Iwata N, Cho KW. Identification of embryonic pancreatic genes using Xenopus DNA microarrays. Dev Dyn. 2009 Jun; 238(6):1455-66. PMID: 19191222; PMCID: PMC4203858.
    24. Karaulanov E, Böttcher RT, Stannek P, Wu W, Rau M, Ogata S, Cho KW, Niehrs C. Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryos. PLoS One. 2009 May 29; 4(5):e5742. PMID: 19492039; PMCID: PMC2683942.
    25. Jarikji Z, Horb LD, Shariff F, Mandato CA, Cho KW, Horb ME. The tetraspanin Tm4sf3 is localized to the ventral pancreas and regulates fusion of the dorsal and ventral pancreatic buds. Development. 2009 Jun; 136(11):1791-800. PMID: 19403659; PMCID: PMC2680106.
    26. Maretto S, Müller PS, Aricescu AR, Cho KW, Bikoff EK, Robertson EJ. Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3. Dev Biol. 2008 Jun 01; 318(1):184-93. PMID: 18448090.
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    27. Ogata S, Morokuma J, Hayata T, Kolle G, Niehrs C, Ueno N, Cho KW. TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis. Genes Dev. 2007 Jul 15; 21(14):1817-31. PMID: 17639085; PMCID: PMC1920175.
    28. Park EC, Hayata T, Cho KW, Han JK. Xenopus cDNA microarray identification of genes with endodermal organ expression. Dev Dyn. 2007 Jun; 236(6):1633-49. PMID: 17474120.
      View in: PubMed
    29. Ogata S, Cho KW. Dissection of organizer and animal pole explants from Xenopus laevis embryos and assembly of a cell adhesion assay. J Vis Exp. 2007; (3):187. PMID: 18978993; PMCID: PMC2535839.
    30. Ogata S, Kawauchi S, Calof A, Cho KW. Plastic embedding and sectioning of Xenopus laevis embryos. J Vis Exp. 2007; (3):188. PMID: 18978994; PMCID: PMC2535840.
    31. Suzawa K, Yukita A, Hayata T, Goto T, Danno H, Michiue T, Cho KW, Asashima M. Xenopus glucose transporter 1 (xGLUT1) is required for gastrulation movement in Xenopus laevis. Int J Dev Biol. 2007; 51(3):183-90. PMID: 17486538.
      View in: PubMed
    32. Li S, Shin Y, Cho KW, Merzdorf CS. The Xfeb gene is directly upregulated by Zic1 during early neural development. Dev Dyn. 2006 Oct; 235(10):2817-27. PMID: 16871635.
      View in: PubMed
    33. Yao LC, Blitz IL, Peiffer DA, Phin S, Wang Y, Ogata S, Cho KW, Arora K, Warrior R. Schnurri transcription factors from Drosophila and vertebrates can mediate Bmp signaling through a phylogenetically conserved mechanism. Development. 2006 Oct; 133(20):4025-34. PMID: 17008448.
      View in: PubMed
    34. Koide T, Hayata T, Cho KW. Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase. Development. 2006 Jun; 133(12):2395-405. PMID: 16687448.
      View in: PubMed
    35. Chalmers AD, Lachani K, Shin Y, Sherwood V, Cho KW, Papalopulu N. Grainyhead-like 3, a transcription factor identified in a microarray screen, promotes the specification of the superficial layer of the embryonic epidermis. Mech Dev. 2006 Sep; 123(9):702-18. PMID: 16916602.
      View in: PubMed
    36. Murato Y, Yamaguti M, Katamura M, Cho KW, Hashimoto C. Two modes of action by which Xenopus hairy2b establishes tissue demarcation in the Spemann-Mangold organizer. Int J Dev Biol. 2006; 50(5):463-71. PMID: 16586347.
      View in: PubMed
    37. Yamaguti M, Cho KW, Hashimoto C. Xenopus hairy2b specifies anterior prechordal mesoderm identity within Spemann's organizer. Dev Dyn. 2005 Sep; 234(1):102-13. PMID: 16059909.
      View in: PubMed
    38. Luo T, Zhang Y, Khadka D, Rangarajan J, Cho KW, Sargent TD. Regulatory targets for transcription factor AP2 in Xenopus embryos. Dev Growth Differ. 2005 Aug; 47(6):403-13. PMID: 16109038.
      View in: PubMed
    39. von Bubnoff A, Peiffer DA, Blitz IL, Hayata T, Ogata S, Zeng Q, Trunnell M, Cho KW. Phylogenetic footprinting and genome scanning identify vertebrate BMP response elements and new target genes. Dev Biol. 2005 May 15; 281(2):210-26. PMID: 15893974.
      View in: PubMed
    40. Koide T, Hayata T, Cho KW. Xenopus as a model system to study transcriptional regulatory networks. Proc Natl Acad Sci U S A. 2005 Apr 05; 102(14):4943-8. PMID: 15795378; PMCID: PMC555977.
    41. Taverner NV, Kofron M, Shin Y, Kabitschke C, Gilchrist MJ, Wylie C, Cho KW, Heasman J, Smith JC. Microarray-based identification of VegT targets in Xenopus. Mech Dev. 2005 Mar; 122(3):333-54. PMID: 15763211.
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    42. Baldessari D, Shin Y, Krebs O, König R, Koide T, Vinayagam A, Fenger U, Mochii M, Terasaka C, Kitayama A, Peiffer D, Ueno N, Eils R, Cho KW, Niehrs C. Global gene expression profiling and cluster analysis in Xenopus laevis. Mech Dev. 2005 Mar; 122(3):441-75. PMID: 15763214.
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    43. Shin Y, Kitayama A, Koide T, Peiffer DA, Mochii M, Liao A, Ueno N, Cho KW. Identification of neural genes using Xenopus DNA microarrays. Dev Dyn. 2005 Feb; 232(2):432-44. PMID: 15614765.
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    44. Arima K, Shiotsugu J, Niu R, Khandpur R, Martinez M, Shin Y, Koide T, Cho KW, Kitayama A, Ueno N, Chandraratna RA, Blumberg B. Global analysis of RAR-responsive genes in the Xenopus neurula using cDNA microarrays. Dev Dyn. 2005 Feb; 232(2):414-31. PMID: 15614783.
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    45. Peiffer DA, Von Bubnoff A, Shin Y, Kitayama A, Mochii M, Ueno N, Cho KW. A Xenopus DNA microarray approach to identify novel direct BMP target genes involved in early embryonic development. Dev Dyn. 2005 Feb; 232(2):445-56. PMID: 15614776.
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    46. Meek LM, Hayata T, Shin YC, Evinger AJ, Cho KW. Cloning and expression of an SH3 domain-containing protein (Xchef-1), a novel downstream target of activin/nodal signaling. Gene Expr Patterns. 2004 Oct; 4(6):719-24. PMID: 15465495.
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    47. Blitz IL, Cho KW, Chang C. Twisted gastrulation loss-of-function analyses support its role as a BMP inhibitor during early Xenopus embryogenesis. Development. 2003 Oct; 130(20):4975-88. PMID: 12952901.
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    48. Tsuji S, Cho KW, Hashimoto C. Expression pattern of a basic helix-loop-helix transcription factor Xhairy2b during Xenopus laevis development. Dev Genes Evol. 2003 Aug; 213(8):407-11. PMID: 12774230.
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    49. Yoshida Y, von Bubnoff A, Ikematsu N, Blitz IL, Tsuzuku JK, Yoshida EH, Umemori H, Miyazono K, Yamamoto T, Cho KW. Tob proteins enhance inhibitory Smad-receptor interactions to repress BMP signaling. Mech Dev. 2003 May; 120(5):629-37. PMID: 12782279.
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    50. Hashimoto-Partyka MK, Yuge M, Cho KW. Nodal signaling in Xenopus gastrulae is cell-autonomous and patterned by beta-catenin. Dev Biol. 2003 Jan 01; 253(1):125-38. PMID: 12490202.
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    51. Tran PH, Peiffer DA, Shin Y, Meek LM, Brody JP, Cho KW. Microarray optimizations: increasing spot accuracy and automated identification of true microarray signals. Nucleic Acids Res. 2002 Jun 15; 30(12):e54. PMID: 12060692; PMCID: PMC117296.
    52. Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho KW. The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling. Genes Dev. 2002 Apr 01; 16(7):820-35. PMID: 11937490; PMCID: PMC186325.
    53. Cho KW, Blitz IL. BMPs, Smads and metalloproteases: extracellular and intracellular modes of negative regulation. Curr Opin Genet Dev. 1998 Aug; 8(4):443-9. PMID: 9729721.
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