James P. Brody

Title(s)Associate Professor, Biomedical Engineering
SchoolSamueli School of Engineering
Address3111 Natural Sciences II
Zot 2715
Irvine CA 92697
Phone(949) 824-2471
ORCID ORCID Icon0000-0002-7995-5197 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Massachusetts Institute of Technology, Cambridge, MABS06/1989Physics
    Princeton University, Princeton, NJPhD06/1994Physics
    Collapse Awards and Honors
    Innovations in Teaching University of California, Irvine2022Jim Brody

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ex vivo discovery of synergistic drug combinations for hematologic malignancies. SLAS Discov. 2024 Mar; 29(2):100129. Ali KA, Shah RD, Dhar A, Myers NM, Nguyen C, Paul A, Mancuso JE, Scott Patterson A, Brody JP, Heiser D. PMID: 38101570.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Predicting moderate drinking behaviors in National Health and Nutrition Examination Survey participants using biochemical and demographical factors with machine learning. Alcohol. 2023 12; 113:1-10. Leaks K, Norden-Krichmar T, Brody JP. PMID: 37543050.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Evaluation of a genetic risk score computed using human chromosomal-scale length variation to predict breast cancer. Hum Genomics. 2023 06 16; 17(1):53. Ko C, Brody JP. PMID: 37328908; PMCID: PMC10273758.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Development of a Machine Learning Model to Predict Recurrence of Oral Tongue Squamous Cell Carcinoma. Cancers (Basel). 2023 May 16; 15(10). Fatapour Y, Abiri A, Kuan EC, Brody JP. PMID: 37345106; PMCID: PMC10216090.
      View in: PubMed   Mentions: 5  
    5. Genetic Risk Scores and Missing Heritability in Ovarian Cancer. Genes (Basel). 2023 03 21; 14(3). Fatapour Y, Brody JP. PMID: 36981032; PMCID: PMC10048518.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. A genetic risk score using human chromosomal-scale length variation can predict schizophrenia. Sci Rep. 2021 09 22; 11(1):18866. Toh C, Brody JP. PMID: 34552103; PMCID: PMC8458522.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. Comment on "comparative analysis of triple-negative breast cancer transcriptomics of Kenyan, African American and Caucasian women" by Saleh et al. Transl Oncol. 2021 Sep; 14(9):101164. Brody JP. PMID: 34171558; PMCID: PMC8243121.
      View in: PubMed   Mentions:
    8. A genetic risk score for glioblastoma multiforme based on copy number variations. Cancer Treat Res Commun. 2021; 27:100352. Ko C, Brody JP. PMID: 33756171.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    9. Genetic risk score for ovarian cancer based on chromosomal-scale length variation. BioData Min. 2021 Mar 09; 14(1):18. Toh C, Brody JP. PMID: 33750420; PMCID: PMC7941679.
      View in: PubMed   Mentions: 3  
    10. Evaluation of a genetic risk score for severity of COVID-19 using human chromosomal-scale length variation. Hum Genomics. 2020 10 09; 14(1):36. Toh C, Brody JP. PMID: 33036646; PMCID: PMC7546598.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsPHPublic Health
    11. Laboratory tests as short-term correlates of stroke. BMC Neurol. 2016 Jul 21; 16:112. Sughrue T, Swiernik MA, Huang Y, Brody JP. PMID: 27439507; PMCID: PMC4955202.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Breast tumor laterality in the United States depends upon the country of birth, but not race. PLoS One. 2014; 9(8):e103313. Sughrue T, Brody JP. PMID: 25083708; PMCID: PMC4118871.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    13. Similarities in the Age-Specific Incidence of Colon and Testicular Cancers. PLoS One. 2013; 8(6):e66694. Soto-Ortiz L, Brody JP. PMID: 23840520; PMCID: PMC3694153.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. Age-specific incidence data indicate four mutations are required for human testicular cancers. PLoS One. 2011; 6(10):e25978. Brody JP. PMID: 21998737; PMCID: PMC3188587.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    15. Reverse engineering the yeast RNR1 transcriptional control system. PLoS One. 2010 Nov 16; 5(11):e13895. Mao G, Brody JP. PMID: 21103376; PMCID: PMC2982837.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    16. Parallel routes of human carcinoma development: implications of the age-specific incidence data. PLoS One. 2009 Sep 23; 4(9):e7053. Brody JP. PMID: 19774079; PMCID: PMC2743810.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Microfabricated arrays of cylindrical wells facilitate single-molecule enzymology of alpha-chymotrypsin. Biotechnol Prog. 2009 Jul-Aug; 25(4):929-37. Chen AY, Jani AS, Zheng L, Burke PJ, Brody JP. PMID: 19610052.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    18. Generation of stable complex gradients across two-dimensional surfaces and three-dimensional gels. Langmuir. 2007 Oct 23; 23(22):10910-2. Mosadegh B, Huang C, Park JW, Shin HS, Chung BG, Hwang SK, Lee KH, Kim HJ, Brody J, Jeon NL. PMID: 17910490.
      View in: PubMed   Mentions: 43     Fields:    
    19. Diffuse large B-cell lymphoma with a novel translocation involving BCL6. Cancer Genet Cytogenet. 2007 Oct 01; 178(1):73-6. Iqbal J, Gupta S, Chen QH, Brody JP, Koduru P. PMID: 17889713.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    20. Dynamic SPR monitoring of yeast nuclear protein binding to a cis-regulatory element. Biochem Biophys Res Commun. 2007 Nov 09; 363(1):153-8. Mao G, Brody JP. PMID: 17850763; PMCID: PMC2699948.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    21. Diversity in the activity of individual enzymes. Curr Pharm Biotechnol. 2005 Dec; 6(6):415-25. Lee AI, Brody JP. PMID: 16375726.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    22. Microlicensing particles and applications. 2005. Quake; Stephen R. and Brody, James P.
    23. Single-molecule enzymology of chymotrypsin using water-in-oil emulsion. Biophys J. 2005 Jun; 88(6):4303-11. Lee AI, Brody JP. PMID: 15764670; PMCID: PMC1305659.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    24. Surface plasmon resonance-based sensors to identify cis-regulatory elements. Anal Chem. 2004 Nov 15; 76(22):6555-9. Lin L, Harris JW, Thompson HG, Brody JP. PMID: 15538776.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    25. Electronic manipulation of DNA, proteins, and nanoparticles for potential circuit assembly. Biosens Bioelectron. 2004 Oct 15; 20(3):606-19. Zheng L, Brody JP, Burke PJ. PMID: 15494246.
      View in: PubMed   Mentions: 37     Fields:    
    26. Manipulating nanoparticles in solution with electrically contacted nanotubes using dielectrophoresis. Langmuir. 2004 Sep 28; 20(20):8612-9. Zheng L, Li S, Brody JP, Burke PJ. PMID: 15379482.
      View in: PubMed   Mentions: 7     Fields:    
    27. Post-translationally modified S12, absent in transformed breast epithelial cells, is not associated with the 26S proteasome and is induced by proteasome inhibitor. Int J Cancer. 2004 Sep 01; 111(3):338-47. Thompson HG, Harris JW, Brody JP. PMID: 15221960.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    28. Identification of the protein Zibra, its genomic organization, regulation, and expression in breast cancer cells. Exp Cell Res. 2004 May 01; 295(2):448-59. Thompson HG, Harris JW, Lin L, Brody JP. PMID: 15093743.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    29. p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells. Oncogene. 2003 Apr 17; 22(15):2322-33. Thompson HG, Harris JW, Wold BJ, Lin F, Brody JP. PMID: 12700667.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    30. Identification and confirmation of a module of coexpressed genes. Genome Res. 2002 Oct; 12(10):1517-22. Thompson HG, Harris JW, Wold BJ, Quake SR, Brody JP. PMID: 12368243; PMCID: PMC187523.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    31. Significance and statistical errors in the analysis of DNA microarray data. Proc Natl Acad Sci U S A. 2002 Oct 01; 99(20):12975-8. Brody JP, Williams BA, Wold BJ, Quake SR. PMID: 12235357; PMCID: PMC130571.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    32. Microarray optimizations: increasing spot accuracy and automated identification of true microarray signals. Nucleic Acids Res. 2002 Jun 15; 30(12):e54. Tran PH, Peiffer DA, Shin Y, Meek LM, Brody JP, Cho KW. PMID: 12060692; PMCID: PMC117296.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    33. The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins. Blood. 2001 Dec 15; 98(13):3778-83. Demiroglu A, Steer EJ, Heath C, Taylor K, Bentley M, Allen SL, Koduru P, Brody JP, Hawson G, Rodwell R, Doody ML, Carnicero F, Reiter A, Goldman JM, Melo JV, Cross NC. PMID: 11739186.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    34. Valveless liquid microswitch. 1998. Brody, James P.
    35. Cytodiagnosis of a primary effusion lymphoma. A case report. Acta Cytol. 1998 Mar-Apr; 42(2):374-6. Vadmal MS, Smilari TF, Brody JP, Koduru P, Hajdu SI. PMID: 9568139.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Microfabricated diffusion based chemical sensor,. 1998. Yager; Paul; Weigl; Bernhard H.; Brody; James P.; Holl; Mark R. .
    37. Biotechnology at low Reynolds numbers. Biophys J. 1996 Dec; 71(6):3430-41. Brody JP, Yager P, Goldstein RE, Austin RH. PMID: 8968612; PMCID: PMC1233830.
      View in: PubMed   Mentions: 66     Fields:    
    38. Deformation and flow of red blood cells in a synthetic lattice: evidence for an active cytoskeleton. Biophys J. 1995 Jun; 68(6):2224-32. Brody JP, Han Y, Austin RH, Bitensky M. PMID: 7647230; PMCID: PMC1282133.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    39. Acute agranular CD4-positive natural killer cell leukemia. Comprehensive clinicopathologic studies including virologic and in vitro culture with inducing agents. Cancer. 1995 May 15; 75(10):2474-83. Brody JP, Allen S, Schulman P, Sun T, Chan WC, Friedman HD, Teichberg S, Koduru P, Cone RW, Loughran TP. PMID: 7736391.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
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