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Blumberg, Bruce

TitleProfessor
InstitutionUniversity of California, Irvine
DepartmentDevelopmental & Cell Biology
Address4103 Natural Sciences II
Zot 2305
CA 92697
Phone(949) 824-8573, 6873
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    Collapse Research 
    Collapse Research Activities and Funding
    2014 Environmental Endocrine Disruptors Gordon Research Conference &Gordon Resea
    NIH/NIEHS R13ES024025Apr 10, 2014 - Mar 31, 2015
    Role: Principal Investigator
    Transgenerational inheritance of prenatal obesogen exposure
    NIH/NIEHS R01ES023316Sep 1, 2013 - Jul 31, 2018
    Role: Principal Investigator
    Endocrine disrupter modulation of SXR in development and lymphomagenesis
    NIH/NIEHS R01ES021832May 15, 2013 - Jan 31, 2018
    Role: Principal Investigator
    Is bisphenol A diglycidyl ether (BADGE) and obesogen?
    NIH/NIEHS R21ES021020Jan 10, 2012 - Dec 31, 2014
    Role: Principal Investigator
    Endocrine disruption by organotins in obesity and diabetes
    NIH/NIEHS R01ES015849Aug 3, 2007 - Apr 30, 2013
    Role: Principal Investigator
    New vertebrate model organism cDNA libraries
    NIH/NCRR R24RR015088Apr 1, 2001 - Mar 31, 2006
    Role: Principal Investigator
    SXR--A TARGET FOR BREAST CANCER PREVENTION AND TREATMENT
    NIH/NCI R21CA087222Jul 1, 2000 - Jun 30, 2002
    Role: Principal Investigator
    BXR SIGNALING IN VERTEBRATE DEVELOPMENT
    NIH/NIGMS R01GM060572Feb 1, 2000 - Jan 31, 2006
    Role: Principal Investigator
    MATERNALLY-EXPRESSED DEVELOPMENTAL GENES IN XENOPUS
    NIH/NICHD F32HD007273Mar 27, 1989
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shoucri BM, Hung VT, Chamorro-García R, Shioda T, Blumberg B. Retinoid X receptor activation during adipogenesis of female mesenchymal stem cells programs a dysfunctional adipocyte. Endocrinology. 2018 May 31. PMID: 29860300.
      View in: PubMed
    2. Chamorro-García R, Shoucri BM, Willner S, Käch H, Janesick A, Blumberg B. Effects of Perinatal Exposure to Dibutyltin Chloride on Fat and Glucose Metabolism in Mice, and Molecular Mechanisms, in Vitro. Environ Health Perspect. 2018 05; 126(5):057006. PMID: 29787037.
      View in: PubMed
    3. Chamorro-Garcia R, Diaz-Castillo C, Shoucri BM, Käch H, Leavitt R, Shioda T, Blumberg B. Ancestral perinatal obesogen exposure results in a transgenerational thrifty phenotype in mice. Nat Commun. 2017 Dec 08; 8(1):2012. PMID: 29222412.
      View in: PubMed
    4. Heindel JJ, Vom Saal FS, Blumberg B, Bovolin P, Calamandrei G, Ceresini G, Cohn BA, Fabbri E, Gioiosa L, Kassotis C, Legler J, La Merrill M, Rizzi L, Machtinger R, Mantovani A, Mendez MA, Montanini L, Molteni L, Nagel SC, Parmigiani S, Panzica G, Paterlini S, Pomatto V, Ruzzin J, Sartor G, Schug TT, Street ME, Suvorov A, Volpi R, Zoeller RT, Palanza P. Correction to: Parma consensus statement on metabolic disruptors. Environ Health. 2017 12 06; 16(1):130. PMID: 29212512.
      View in: PubMed
    5. Shoucri BM, Martinez ES, Abreo TJ, Hung VT, Moosova Z, Shioda T, Blumberg B. Retinoid X Receptor Activation Alters the Chromatin Landscape To Commit Mesenchymal Stem Cells to the Adipose Lineage. Endocrinology. 2017 10 01; 158(10):3109-3125. PMID: 28977589.
      View in: PubMed
    6. Bornman MS, Aneck-Hahn NH, de Jager C, Wagenaar GM, Bouwman H, Barnhoorn IEJ, Patrick SM, Vandenberg LN, Kortenkamp A, Blumberg B, Kimmins S, Jegou B, Auger J, DiGangi J, Heindel JJ. Endocrine Disruptors and Health Effects in Africa: A Call for Action. Environ Health Perspect. 2017 08 22; 125(8):085005. PMID: 28935616.
      View in: PubMed
    7. Janesick A, Tang W, Nguyen TTL, Blumberg B. RARß2 is required for vertebrate somitogenesis. Development. 2017 06 01; 144(11):1997-2008. PMID: 28432217.
      View in: PubMed
    8. Vandenberg LN, Blumberg B, Antoniou MN, Benbrook CM, Carroll L, Colborn T, Everett LG, Hansen M, Landrigan PJ, Lanphear BP, Mesnage R, Vom Saal FS, Welshons WV, Myers JP. Is it time to reassess current safety standards for glyphosate-based herbicides? J Epidemiol Community Health. 2017 Jun; 71(6):613-618. PMID: 28320775.
      View in: PubMed
    9. Janesick AS, Dimastrogiovanni G, Chamorro-Garcia R, Blumberg B. Reply to "Comment on 'On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens'". Environ Health Perspect. 2017 01 01; 125(1):A12-A14. PMID: 28055946.
      View in: PubMed
    10. Zhu J, Janesick A, Wu L, Hu L, Tang W, Blumberg B, Shi H. The unexpected teratogenicity of RXR antagonist UVI3003 via activation of PPAR? in Xenopus tropicalis. Toxicol Appl Pharmacol. 2017 Jan 01; 314:91-97. PMID: 27894914.
      View in: PubMed
    11. Heindel JJ, Blumberg B, Cave M, Machtinger R, Mantovani A, Mendez MA, Nadal A, Palanza P, Panzica G, Sargis R, Vandenberg LN, Vom Saal F. Metabolism disrupting chemicals and metabolic disorders. Reprod Toxicol. 2017 03; 68:3-33. PMID: 27760374.
      View in: PubMed
    12. Janesick AS, Blumberg B. Reply. Am J Obstet Gynecol. 2016 10; 215(4):533. PMID: 27242202.
      View in: PubMed
    13. Lind L, Lind PM, Lejonklou MH, Dunder L, Bergman Å, Guerrero-Bosagna C, Lampa E, Lee HK, Legler J, Nadal A, Pak YK, Phipps RP, Vandenberg LN, Zalko D, Ågerstrand M, Öberg M, Blumberg B, Heindel JJ, Birnbaum LS. Uppsala Consensus Statement on Environmental Contaminants and the Global Obesity Epidemic. Environ Health Perspect. 2016 05 01; 124(5):A81-3. PMID: 27135406.
      View in: PubMed
    14. Myers JP, Antoniou MN, Blumberg B, Carroll L, Colborn T, Everett LG, Hansen M, Landrigan PJ, Lanphear BP, Mesnage R, Vandenberg LN, Vom Saal FS, Welshons WV, Benbrook CM. Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement. Environ Health. 2016 Feb 17; 15:19. PMID: 26883814; PMCID: PMC4756530.
    15. Wang J, Bi W, Zhao W, Varghese M, Koch RJ, Walker RH, Chandraratna RA, Sanders ME, Janesick A, Blumberg B, Ward L, Ho L, Pasinetti GM. Selective brain penetrable Nurr1 transactivator for treating Parkinson's disease. Oncotarget. 2016 Feb 16; 7(7):7469-79. PMID: 26862735; PMCID: PMC4884932.
    16. Janesick AS, Blumberg B. Obesogens: an emerging threat to public health. Am J Obstet Gynecol. 2016 05; 214(5):559-65. PMID: 26829510; PMCID: PMC4851574 [Available on 05/01/17].
    17. Janesick AS, Dimastrogiovanni G, Vanek L, Boulos C, Chamorro-García R, Tang W, Blumberg B. On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens. Environ Health Perspect. 2016 08; 124(8):1214-26. PMID: 26757984; PMCID: PMC4977052.
    18. Pedram A, Razandi M, Blumberg B, Levin ER. Membrane and nuclear estrogen receptor a collaborate to suppress adipogenesis but not triglyceride content. FASEB J. 2016 Jan; 30(1):230-40. PMID: 26373802; PMCID: PMC4684544 [Available on 01/01/17].
    19. Bergman Å, Becher G, Blumberg B, Bjerregaard P, Bornman R, Brandt I, Casey SC, Frouin H, Giudice LC, Heindel JJ, Iguchi T, Jobling S, Kidd KA, Kortenkamp A, Lind PM, Muir D, Ochieng R, Ropstad E, Ross PS, Skakkebaek NE, Toppari J, Vandenberg LN, Woodruff TJ, Zoeller RT. Manufacturing doubt about endocrine disrupter science--A rebuttal of industry-sponsored critical comments on the UNEP/WHO report "State of the Science of Endocrine Disrupting Chemicals 2012". Regul Toxicol Pharmacol. 2015 Dec; 73(3):1007-17. PMID: 26239693.
      View in: PubMed
    20. Heindel JJ, Vom Saal FS, Blumberg B, Bovolin P, Calamandrei G, Ceresini G, Cohn BA, Fabbri E, Gioiosa L, Kassotis C, Legler J, La Merrill M, Rizzir L, Machtinger R, Mantovani A, Mendez MA, Montanini L, Molteni L, Nagel SC, Parmigiani S, Panzica G, Paterlini S, Pomatto V, Ruzzin J, Sartor G, Schug TT, Street ME, Suvorov A, Volpi R, Zoeller RT, Palanza P. Parma consensus statement on metabolic disruptors. Environ Health. 2015 06 20; 14:54. PMID: 26092037.
      View in: PubMed
    21. Azuma K, Casey SC, Urano T, Horie-Inoue K, Ouchi Y, Blumberg B, Inoue S. Pregnane X receptor knockout mice display aging-dependent wearing of articular cartilage. PLoS One. 2015; 10(3):e0119177. PMID: 25749104.
      View in: PubMed
    22. Legler J, Fletcher T, Govarts E, Porta M, Blumberg B, Heindel JJ, Trasande L. Obesity, diabetes, and associated costs of exposure to endocrine-disrupting chemicals in the European Union. J Clin Endocrinol Metab. 2015 Apr; 100(4):1278-88. PMID: 25742518; PMCID: PMC4399302.
    23. Lille-Langøy R, Goldstone JV, Rusten M, Milnes MR, Male R, Stegeman JJ, Blumberg B, Goksøyr A. Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently. Toxicol Appl Pharmacol. 2015 Apr 01; 284(1):54-64. PMID: 25680588; PMCID: PMC4387200.
    24. Janesick A, Wu SC, Blumberg B. Retinoic acid signaling and neuronal differentiation. Cell Mol Life Sci. 2015 Apr; 72(8):1559-76. PMID: 25558812.
      View in: PubMed
    25. Chamorro-García R, Blumberg B. Transgenerational effects of obesogens and the obesity epidemic. Curr Opin Pharmacol. 2014 Dec; 19:153-8. PMID: 25460228; PMCID: PMC4297575.
    26. Janesick AS, Shioda T, Blumberg B. Transgenerational inheritance of prenatal obesogen exposure. Mol Cell Endocrinol. 2014 Dec; 398(1-2):31-5. PMID: 25218215; PMCID: PMC4262625.
    27. Blumberg B. Andrés Carrasco (1946-2014). Dev Biol. 2014 Sep 01; 393(1):1-2. PMID: 25275141.
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    28. Janesick A, Nguyen TT, Aisaki K, Igarashi K, Kitajima S, Chandraratna RA, Kanno J, Blumberg B. Active repression by RAR? signaling is required for vertebrate axial elongation. Development. 2014 Jun; 141(11):2260-70. PMID: 24821986.
      View in: PubMed
    29. Kamstra JH, Hruba E, Blumberg B, Janesick A, Mandrup S, Hamers T, Legler J. Transcriptional and epigenetic mechanisms underlying enhanced in vitro adipocyte differentiation by the brominated flame retardant BDE-47. Environ Sci Technol. 2014 Apr 01; 48(7):4110-9. PMID: 24559133; PMCID: PMC3983330.
    30. Ortiz L, Nakamura B, Li X, Blumberg B, Luderer U. Reprint of "In utero exposure to benzo[a]pyrene increases adiposity and causes hepatic steatosis in female mice, and glutathione deficiency is protective". Toxicol Lett. 2014 Oct 15; 230(2):314-21. PMID: 24291350.
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    31. Ortiz L, Nakamura B, Li X, Blumberg B, Luderer U. In utero exposure to benzo[a]pyrene increases adiposity and causes hepatic steatosis in female mice, and glutathione deficiency is protective. Toxicol Lett. 2013 Nov 25; 223(2):260-7. PMID: 24107266; PMCID: PMC3856224.
    32. Bergman Å, Andersson AM, Becher G, van den Berg M, Blumberg B, Bjerregaard P, Bornehag CG, Bornman R, Brandt I, Brian JV, Casey SC, Fowler PA, Frouin H, Giudice LC, Iguchi T, Hass U, Jobling S, Juul A, Kidd KA, Kortenkamp A, Lind M, Martin OV, Muir D, Ochieng R, Olea N, Norrgren L, Ropstad E, Ross PS, Rudén C, Scheringer M, Skakkebaek NE, Söder O, Sonnenschein C, Soto A, Swan S, Toppari J, Tyler CR, Vandenberg LN, Vinggaard AM, Wiberg K, Zoeller RT. Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors. Environ Health. 2013 Aug 27; 12:69. PMID: 23981490; PMCID: PMC3765603.
    33. Janesick A, Abbey R, Chung C, Liu S, Taketani M, Blumberg B. ERF and ETV3L are retinoic acid-inducible repressors required for primary neurogenesis. Development. 2013 Aug; 140(15):3095-106. PMID: 23824578.
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    34. Goran MI, Dumke K, Bouret SG, Kayser B, Walker RW, Blumberg B. The obesogenic effect of high fructose exposure during early development. Nat Rev Endocrinol. 2013 Aug; 9(8):494-500. PMID: 23732284; PMCID: PMC4916951.
    35. Chamorro-García R, Sahu M, Abbey RJ, Laude J, Pham N, Blumberg B. Transgenerational inheritance of increased fat depot size, stem cell reprogramming, and hepatic steatosis elicited by prenatal exposure to the obesogen tributyltin in mice. Environ Health Perspect. 2013 Mar; 121(3):359-66. PMID: 23322813; PMCID: PMC3621201.
    36. Li X, Pham HT, Janesick AS, Blumberg B. Triflumizole is an obesogen in mice that acts through peroxisome proliferator activated receptor gamma (PPAR?). Environ Health Perspect. 2012 Dec; 120(12):1720-6. PMID: 23086663; PMCID: PMC3548286.
    37. Boekelheide K, Blumberg B, Chapin RE, Cote I, Graziano JH, Janesick A, Lane R, Lillycrop K, Myatt L, States JC, Thayer KA, Waalkes MP, Rogers JM. Predicting later-life outcomes of early-life exposures. Environ Health Perspect. 2012 Oct; 120(10):1353-61. PMID: 22672778; PMCID: PMC3491941.
    38. Chamorro-García R, Kirchner S, Li X, Janesick A, Casey SC, Chow C, Blumberg B. Bisphenol A diglycidyl ether induces adipogenic differentiation of multipotent stromal stem cells through a peroxisome proliferator-activated receptor gamma-independent mechanism. Environ Health Perspect. 2012 Jul; 120(7):984-9. PMID: 22763116; PMCID: PMC3404682.
    39. Casey SC, Blumberg B. The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. Mol Endocrinol. 2012 Jun; 26(6):916-25. PMID: 22496360; PMCID: PMC3355537.
    40. Janesick A, Shiotsugu J, Taketani M, Blumberg B. RIPPLY3 is a retinoic acid-inducible repressor required for setting the borders of the pre-placodal ectoderm. Development. 2012 Mar; 139(6):1213-24. PMID: 22354841; PMCID: PMC3283127.
    41. Janesick A, Blumberg B. Obesogens, stem cells and the developmental programming of obesity. Int J Androl. 2012 Jun; 35(3):437-48. PMID: 22372658; PMCID: PMC3358413.
    42. Hennig B, Ormsbee L, McClain CJ, Watkins BA, Blumberg B, Bachas LG, Sanderson W, Thompson C, Suk WA. Nutrition can modulate the toxicity of environmental pollutants: implications in risk assessment and human health. Environ Health Perspect. 2012 Jun; 120(6):771-4. PMID: 22357258; PMCID: PMC3385446.
    43. Igarashi K, Kitajima S, Aisaki K, Tanemura K, Taquahashi Y, Moriyama N, Ikeno E, Matsuda N, Saga Y, Blumberg B, Kanno J. Development of humanized steroid and xenobiotic receptor mouse by homologous knock-in of the human steroid and xenobiotic receptor ligand binding domain sequence. J Toxicol Sci. 2012; 37(2):373-80. PMID: 22467028.
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    44. Schug TT, Janesick A, Blumberg B, Heindel JJ. Endocrine disrupting chemicals and disease susceptibility. J Steroid Biochem Mol Biol. 2011 Nov; 127(3-5):204-15. PMID: 21899826.
      View in: PubMed
    45. Blumberg B, Iguchi T, Odermatt A. Endocrine disrupting chemicals. J Steroid Biochem Mol Biol. 2011 Oct; 127(1-2):1-3. PMID: 21839836.
      View in: PubMed
    46. Casey SC, Nelson EL, Turco GM, Janes MR, Fruman DA, Blumberg B. B-1 cell lymphoma in mice lacking the steroid and xenobiotic receptor, SXR. Mol Endocrinol. 2011 Jun; 25(6):933-43. PMID: 21436254; PMCID: PMC3100607.
    47. Li X, Ycaza J, Blumberg B. The environmental obesogen tributyltin chloride acts via peroxisome proliferator activated receptor gamma to induce adipogenesis in murine 3T3-L1 preadipocytes. J Steroid Biochem Mol Biol. 2011 Oct; 127(1-2):9-15. PMID: 21397693; PMCID: PMC3281769.
    48. Janesick A, Blumberg B. Endocrine disrupting chemicals and the developmental programming of adipogenesis and obesity. Birth Defects Res C Embryo Today. 2011 Mar; 93(1):34-50. PMID: 21425440; PMCID: PMC4919125.
    49. Janesick A, Blumberg B. Minireview: PPAR? as the target of obesogens. J Steroid Biochem Mol Biol. 2011 Oct; 127(1-2):4-8. PMID: 21251979; PMCID: PMC3116997.
    50. Azuma K, Casey SC, Ito M, Urano T, Horie K, Ouchi Y, Kirchner S, Blumberg B, Inoue S. Pregnane X receptor knockout mice display osteopenia with reduced bone formation and enhanced bone resorption. J Endocrinol. 2010 Dec; 207(3):257-63. PMID: 20876238; PMCID: PMC4476281.
    51. Hellsten U, Harland RM, Gilchrist MJ, Hendrix D, Jurka J, Kapitonov V, Ovcharenko I, Putnam NH, Shu S, Taher L, Blitz IL, Blumberg B, Dichmann DS, Dubchak I, Amaya E, Detter JC, Fletcher R, Gerhard DS, Goodstein D, Graves T, Grigoriev IV, Grimwood J, Kawashima T, Lindquist E, Lucas SM, Mead PE, Mitros T, Ogino H, Ohta Y, Poliakov AV, Pollet N, Robert J, Salamov A, Sater AK, Schmutz J, Terry A, Vize PD, Warren WC, Wells D, Wills A, Wilson RK, Zimmerman LB, Zorn AM, Grainger R, Grammer T, Khokha MK, Richardson PM, Rokhsar DS. The genome of the Western clawed frog Xenopus tropicalis. Science. 2010 Apr 30; 328(5978):633-6. PMID: 20431018; PMCID: PMC2994648.
    52. Kirchner S, Kieu T, Chow C, Casey S, Blumberg B. Prenatal exposure to the environmental obesogen tributyltin predisposes multipotent stem cells to become adipocytes. Mol Endocrinol. 2010 Mar; 24(3):526-39. PMID: 20160124; PMCID: PMC2840805.
    53. Grün F, Blumberg B. Minireview: the case for obesogens. Mol Endocrinol. 2009 Aug; 23(8):1127-34. PMID: 19372238; PMCID: PMC2718750.
    54. Grün F, Blumberg B. Endocrine disrupters as obesogens. Mol Cell Endocrinol. 2009 May 25; 304(1-2):19-29. PMID: 19433244; PMCID: PMC2713042.
    55. Zhou C, Verma S, Blumberg B. The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism. Nucl Recept Signal. 2009; 7:e001. PMID: 19240808; PMCID: PMC2646121.
    56. Verma S, Tabb MM, Blumberg B. Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cells. BMC Cancer. 2009 Jan 05; 9:3. PMID: 19123943; PMCID: PMC2631587.
    57. Milnes MR, Garcia A, Grossman E, Grün F, Shiotsugu J, Tabb MM, Kawashima Y, Katsu Y, Watanabe H, Iguchi T, Blumberg B. Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model species. Environ Health Perspect. 2008 Jul; 116(7):880-5. PMID: 18629309; PMCID: PMC2453155.
    58. Blumberg B, Izpisúa Belmonte JC. Subtractive hybridization and construction of cDNA libraries. Methods Mol Biol. 2008; 461:569-87. PMID: 19030824.
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    59. Kumagai J, Fujimura T, Takahashi S, Urano T, Ogushi T, Horie-Inoue K, Ouchi Y, Kitamura T, Muramatsu M, Blumberg B, Inoue S. Cytochrome P450 2B6 is a growth-inhibitory and prognostic factor for prostate cancer. Prostate. 2007 Jul 01; 67(10):1029-37. PMID: 17455229.
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    60. Grün F, Blumberg B. Perturbed nuclear receptor signaling by environmental obesogens as emerging factors in the obesity crisis. Rev Endocr Metab Disord. 2007 Jun; 8(2):161-71. PMID: 17657605.
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    61. Mensah-Osman EJ, Thomas DG, Tabb MM, Larios JM, Hughes DP, Giordano TJ, Lizyness ML, Rae JM, Blumberg B, Hollenberg PF, Baker LH. Expression levels and activation of a PXR variant are directly related to drug resistance in osteosarcoma cell lines. Cancer. 2007 Mar 01; 109(5):957-65. PMID: 17279585; PMCID: PMC3125968.
    62. Adam MP, Schelley S, Gallagher R, Brady AN, Barr K, Blumberg B, Shieh JT, Graham J, Slavotinek A, Martin M, Keppler-Noreuil K, Storm AL, Hudgins L. Clinical features and management issues in Mowat-Wilson syndrome. Am J Med Genet A. 2006 Dec 15; 140(24):2730-41. PMID: 17103451.
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    63. Zhou C, Poulton EJ, Grün F, Bammler TK, Blumberg B, Thummel KE, Eaton DL. The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor. Mol Pharmacol. 2007 Jan; 71(1):220-9. PMID: 17028159.
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    64. Zhou C, Tabb MM, Nelson EL, Grün F, Verma S, Sadatrafiei A, Lin M, Mallick S, Forman BM, Thummel KE, Blumberg B. Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation. J Clin Invest. 2006 Aug; 116(8):2280-2289. PMID: 16841097; PMCID: PMC1501109.
    65. Grün F, Blumberg B. Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling. Endocrinology. 2006 Jun; 147(6 Suppl):S50-5. PMID: 16690801.
      View in: PubMed
    66. Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, Thummel KE. Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. J Clin Invest. 2006 Jun; 116(6):1703-12. PMID: 16691293; PMCID: PMC1459072.
    67. Grün F, Watanabe H, Zamanian Z, Maeda L, Arima K, Cubacha R, Gardiner DM, Kanno J, Iguchi T, Blumberg B. Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates. Mol Endocrinol. 2006 Sep; 20(9):2141-55. PMID: 16613991.
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    68. Ichikawa T, Horie-Inoue K, Ikeda K, Blumberg B, Inoue S. Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells. J Biol Chem. 2006 Jun 23; 281(25):16927-34. PMID: 16606623.
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    69. Miki Y, Suzuki T, Kitada K, Yabuki N, Shibuya R, Moriya T, Ishida T, Ohuchi N, Blumberg B, Sasano H. Expression of the steroid and xenobiotic receptor and its possible target gene, organic anion transporting polypeptide-A, in human breast carcinoma. Cancer Res. 2006 Jan 01; 66(1):535-42. PMID: 16397270.
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    70. Tabb MM, Blumberg B. New modes of action for endocrine-disrupting chemicals. Mol Endocrinol. 2006 Mar; 20(3):475-82. PMID: 16037129.
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    71. Arima K, Shiotsugu J, Niu R, Khandpur R, Martinez M, Shin Y, Koide T, Cho KW, Kitayama A, Ueno N, Chandraratna RA, Blumberg B. Global analysis of RAR-responsive genes in the Xenopus neurula using cDNA microarrays. Dev Dyn. 2005 Feb; 232(2):414-31. PMID: 15614783.
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    72. Miki Y, Suzuki T, Tazawa C, Blumberg B, Sasano H. Steroid and xenobiotic receptor (SXR), cytochrome P450 3A4 and multidrug resistance gene 1 in human adult and fetal tissues. Mol Cell Endocrinol. 2005 Feb 28; 231(1-2):75-85. PMID: 15713537.
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    73. Zhou C, Tabb MM, Sadatrafiei A, Grün F, Sun A, Blumberg B. Hyperforin, the active component of St. John's wort, induces IL-8 expression in human intestinal epithelial cells via a MAPK-dependent, NF-kappaB-independent pathway. J Clin Immunol. 2004 Nov; 24(6):623-36. PMID: 15622447.
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    74. Zhou C, Tabb MM, Sadatrafiei A, Grün F, Blumberg B. Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. Drug Metab Dispos. 2004 Oct; 32(10):1075-82. PMID: 15269186.
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    75. Shiotsugu J, Katsuyama Y, Arima K, Baxter A, Koide T, Song J, Chandraratna RA, Blumberg B. Multiple points of interaction between retinoic acid and FGF signaling during embryonic axis formation. Development. 2004 Jun; 131(11):2653-67. PMID: 15128657.
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    76. Tabb MM, Kholodovych V, Grün F, Zhou C, Welsh WJ, Blumberg B. Highly chlorinated PCBs inhibit the human xenobiotic response mediated by the steroid and xenobiotic receptor (SXR). Environ Health Perspect. 2004 Feb; 112(2):163-9. PMID: 14754570; PMCID: PMC1241825.
    77. Tabb MM, Sun A, Zhou C, Grün F, Errandi J, Romero K, Pham H, Inoue S, Mallick S, Lin M, Forman BM, Blumberg B. Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR. J Biol Chem. 2003 Nov 07; 278(45):43919-27. PMID: 12920130.
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    78. Weston AD, Blumberg B, Underhill TM. Active repression by unliganded retinoid receptors in development: less is sometimes more. J Cell Biol. 2003 Apr 28; 161(2):223-8. PMID: 12719467; PMCID: PMC2172895.
    79. Zhou C, Blumberg B. Overlapping gene structure of human VLCAD and DLG4. Gene. 2003 Feb 27; 305(2):161-6. PMID: 12609736.
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