Jogeshwar Mukherjee

Title(s)Professor In Residence, Radiological Sciences
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-2018
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    Collapse Research 
    Collapse Research Activities and Funding
    PET imaging of a4b2 nicotinic receptor upregulation and smoking cessation
    NIH R01DA044760Jul 1, 2017 - Apr 30, 2022
    Role: Co-Principal Investigator
    Fluorine-18 Labeled Functional Dopamine Receptor Imaging Agents
    NIH R21DA038866Jul 1, 2015 - Jun 30, 2019
    Role: Principal Investigator
    Cyclotron for PET Radiopharmaceuticals
    NIH S10OD012259Apr 19, 2013 - Apr 18, 2016
    Role: Principal Investigator
    Imaging Adrenergic Stimulation of Brown Adipose Tissue
    NIH R21DK092917Sep 1, 2011 - Aug 31, 2014
    Role: Principal Investigator
    PET Imaging Agent for Diabetes Mellitus
    NIH RC1DK087352Sep 19, 2009 - Aug 31, 2012
    Role: Principal Investigator
    Small Animal MicroCT
    NIH S10RR024546May 1, 2009 - Apr 30, 2010
    Role: Principal Investigator
    Dopamine D2/D3 Receptor Agonists for PET Imaging
    NIH R01EB006110Aug 6, 2007 - Apr 30, 2012
    Role: Principal Investigator
    18F-Mefway PET for Human Aging and Alzheimer's Disease
    NIH R33AG030524Jul 1, 2007 - Aug 31, 2015
    Role: Principal Investigator
    18F-Mefway for Imaging Mood Disorders and Alzheimer's Disease
    NIH R21AG030524Jul 1, 2007 - Aug 31, 2011
    Role: Principal Investigator
    PET Imaging agents for a4b2 Nicotinic Receptors
    NIH RF1AG029479Jun 1, 2007 - Jul 31, 2022
    Role: Principal Investigator
    PET Imaging Agents for a4b2 Nicotinic Receptors
    NIH R01AG029479Jun 1, 2007 - Aug 14, 2019
    Role: Principal Investigator
    Small Animal PET (microPET)
    NIH S10RR019269Apr 1, 2007 - Mar 31, 2008
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Glutamate's Effects on the N-Methyl-D-Aspartate (NMDA) Receptor Ion Channel in Alzheimer's Disease Brain: Challenges for PET Radiotracer Development for Imaging the NMDA Ion Channel. Molecules. 2023 Dec 19; 29(1). Shah NM, Ghazaryan N, Gonzaga NL, Paclibar CG, Biju AP, Liang C, Mukherjee J. PMID: 38202606; PMCID: PMC10779680.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    2. Synthesis and Evaluation of Compound Targeting α7 and β2 Subunits in Nicotinic Acetylcholinergic Receptor. Molecules. 2023 Dec 16; 28(24). Singh K, Ngo A, Keerthisinghe OV, Patel KK, Liang C, Mukherjee J. PMID: 38138615; PMCID: PMC10745926.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    3. A simplified protocol for the automated production of 2-[18 F]fluoro-3-[2-((S)-3-pyrrolinyl)methoxy]pyridine ([18 F]nifene) on an IBA Synthera® module. J Labelled Comp Radiopharm. 2024 Jan; 67(1):31-36. Bhuiyan M, Souris J, Kucharski A, Freifelder R, Mukherjee J, Chen CT. PMID: 37927198.
      View in: PubMed   Mentions:    Fields:    
    4. Evaluation of an Image-Derived Input Function for Kinetic Modeling of Nicotinic Acetylcholine Receptor-Binding PET Ligands in Mice. Int J Mol Sci. 2023 Oct 24; 24(21). Zammit M, Kao CM, Zhang HJ, Tsai HM, Holderman N, Mitchell S, Tanios E, Bhuiyan M, Freifelder R, Kucharski A, Green WN, Mukherjee J, Chen CT. PMID: 37958495; PMCID: PMC10650787.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. [125I]INFT: Synthesis and Evaluation of a New Imaging Agent for Tau Protein in Post-Mortem Human Alzheimer's Disease Brain. Molecules. 2023 Jul 31; 28(15). Limpengco RR, Liang C, Sandhu YK, Mukherjee J. PMID: 37570739; PMCID: PMC10421386.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Comparison of Monoamine Oxidase-A, Aβ Plaques, Tau, and Translocator Protein Levels in Postmortem Human Alzheimer's Disease Brain. Int J Mol Sci. 2023 Jun 28; 24(13). Syed AU, Liang C, Patel KK, Mondal R, Kamalia VM, Moran TR, Ahmed ST, Mukherjee J. PMID: 37445985; PMCID: PMC10341404.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Measurement of Aβ Amyloid Plaques and Tau Protein in Postmortem Human Alzheimer's Disease Brain by Autoradiography Using [18F]Flotaza, [125I]IBETA, [124/125I]IPPI and Immunohistochemistry Analysis Using QuPath. Biomedicines. 2023 Mar 27; 11(4). Mondal R, Sandhu YK, Kamalia VM, Delaney BA, Syed AU, Nguyen GAH, Moran TR, Limpengco RR, Liang C, Mukherjee J. PMID: 37189652; PMCID: PMC10136263.
      View in: PubMed   Mentions: 3  
    8. Abnormal [18 F]NIFENE binding in transgenic 5xFAD mouse model of Alzheimer's disease: In vivo PET/CT imaging studies of α4β2* nicotinic acetylcholinergic receptors and in vitro correlations with Aβ plaques. Synapse. 2023 05; 77(3):e22265. Liang C, Nguyen GA, Danh TB, Sandhu AK, Melkonyan LL, Syed AU, Mukherjee J. PMID: 36749986; PMCID: PMC10148164.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    9. Development of [124/125I]IAZA as a New Proteinopathy Imaging Agent for Alzheimer's Disease. Molecules. 2023 Jan 15; 28(2). Reddy TT, Iguban MH, Melkonyan LL, Shergill J, Liang C, Mukherjee J. PMID: 36677925; PMCID: PMC9863004.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Elevated Monoamine Oxidase-A in Anterior Cingulate of Post-Mortem Human Parkinson's Disease: A Potential Surrogate Biomarker for Lewy Bodies? Cells. 2022 Dec 10; 11(24). Mukherjee J, Ladwa RM, Liang C, Syed AU. PMID: 36552764.
      View in: PubMed   Mentions: 5     Fields:    
    11. Trapping of Nicotinic Acetylcholine Receptor Ligands Assayed by In Vitro Cellular Studies and In Vivo PET Imaging. J Neurosci. 2023 01 04; 43(1):2-13. Zhang HJ, Zammit M, Kao CM, Govind AP, Mitchell S, Holderman N, Bhuiyan M, Freifelder R, Kucharski A, Zhuang X, Mukherjee J, Chen CT, Green WN. PMID: 36028313; PMCID: PMC9838697.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    12. [124I]IBETA: A New Aβ Plaque Positron Emission Tomography Imaging Agent for Alzheimer's Disease. Molecules. 2022 Jul 17; 27(14). Nguyen GAH, Liang C, Mukherjee J. PMID: 35889425; PMCID: PMC9319930.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    13. Four-modality imaging of unmedicated subjects with schizophrenia: 18F-fluorodeoxyglucose and 18F-fallypride PET, diffusion tensor imaging, and MRI. Psychiatry Res Neuroimaging. 2022 03; 320:111428. Buchsbaum MS, Mitelman SA, Christian BT, Merrill BM, Buchsbaum BR, Mitelman D, Mukherjee J, Lehrer DS. PMID: 34954446.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. [18F]Nifene PET/CT Imaging in Mice: Improved Methods and Preliminary Studies of α4β2* Nicotinic Acetylcholinergic Receptors in Transgenic A53T Mouse Model of α-Synucleinopathy and Post-Mortem Human Parkinson's Disease. Molecules. 2021 Dec 04; 26(23). Campoy AT, Liang C, Ladwa RM, Patel KK, Patel IH, Mukherjee J. PMID: 34885943; PMCID: PMC8659100.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    15. Reading abilities and dopamine D2/D3 receptor availability: An inverted U-shaped association in subjects with schizophrenia. Brain Lang. 2021 12; 223:105046. Mitelman SA, Buchsbaum MS, Vyas NS, Christian BT, Merrill BM, Buchsbaum BR, Mitelman AM, Mukherjee J, Lehrer DS. PMID: 34763166.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    16. [ 18 F]FDG PET/CT Studies in Transgenic Hualpha-Syn (A53T) Parkinson's Disease Mouse Model of α-Synucleinopathy. Front Neurosci. 2021; 15:676257. Mondal R, Campoy AT, Liang C, Mukherjee J. PMID: 34211366; PMCID: PMC8239288.
      View in: PubMed   Mentions: 7  
    17. Development and evaluation of [18F]Flotaza for Aβ plaque imaging in postmortem human Alzheimer's disease brain. Bioorg Med Chem Lett. 2021 08 15; 46:128164. Kaur H, Felix MR, Liang C, Mukherjee J. PMID: 34082067; PMCID: PMC8379902.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    18. Development and evaluation of [125 I]IPPI for Tau imaging in postmortem human Alzheimer's disease brain. Synapse. 2021 01; 75(1):e22183. Mukherjee J, Liang C, Patel KK, Lam PQ, Mondal R. PMID: 32722889; PMCID: PMC8373522.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    19. Dopamine receptor density and white mater integrity: 18F-fallypride positron emission tomography and diffusion tensor imaging study in healthy and schizophrenia subjects. Brain Imaging Behav. 2020 Jun; 14(3):736-752. Mitelman SA, Buchsbaum MS, Christian BT, Merrill BM, Buchsbaum BR, Mukherjee J, Lehrer DS. PMID: 30523488.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    20. Development of zirconium-89 PET for in vivo imaging of alpha-klotho. Am J Nucl Med Mol Imaging. 2020; 10(2):95-105. Lau WL, Liang C, Liu H, Singh K, Mukherjee J. PMID: 32419978; PMCID: PMC7218695.
      View in: PubMed   Mentions: 2  
    21. Positive association between cerebral grey matter metabolism and dopamine D2/D3 receptor availability in healthy and schizophrenia subjects: An 18F-fluorodeoxyglucose and 18F-fallypride positron emission tomography study. World J Biol Psychiatry. 2020 06; 21(5):368-382. Mitelman SA, Buchsbaum MS, Christian BT, Merrill BM, Buchsbaum BR, Mukherjee J, Lehrer DS. PMID: 31552783.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    22. Dual targeting agents for Aβ plaque/P-glycoprotein and Aβ plaque/nicotinic acetylcholine α4β2* receptors-potential approaches to facilitate Aβ plaque removal in Alzheimer's disease brain. Med Chem Res. 2018 Jun; 27(6):1634-1646. Samra GK, Dang K, Ho H, Baranwal A, Mukherjee J. PMID: 29937677; PMCID: PMC6013267.
      View in: PubMed   Mentions: 6  
    23. Development of fluorescence imaging probes for nicotinic acetylcholine α4β2∗ receptors. Bioorg Med Chem Lett. 2018 02 01; 28(3):371-377. Samra GK, Intskirveli I, Govind AP, Liang C, Lazar R, Green WN, Metherate R, Mukherjee J. PMID: 29277457; PMCID: PMC6004331.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    24. Human brain imaging of nicotinic acetylcholine α4β2* receptors using [18 F]Nifene: Selectivity, functional activity, toxicity, aging effects, gender effects, and extrathalamic pathways. J Comp Neurol. 2018 Jan 01; 526(1):80-95. Mukherjee J, Lao PJ, Betthauser TJ, Samra GK, Pan ML, Patel IH, Liang C, Metherate R, Christian BT. PMID: 28875553; PMCID: PMC5788574.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    25. Human biodistribution and dosimetry of [18F]nifene, an α4β2* nicotinic acetylcholine receptor PET tracer. Nucl Med Biol. 2017 Dec; 55:7-11. Betthauser TJ, Hillmer AT, Lao PJ, Ehlerding E, Mukherjee J, Stone CK, Christian BT. PMID: 28963927; PMCID: PMC5709231.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    26. D2/D3 dopamine receptor binding with [F-18]fallypride correlates of executive function in medication-naïve patients with schizophrenia. Schizophr Res. 2018 02; 192:442-456. Vyas NS, Buchsbaum MS, Lehrer DS, Merrill BM, DeCastro A, Doninger NA, Christian BT, Mukherjee J. PMID: 28576546.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    27. [18 F]Nifene test-retest reproducibility in first-in-human imaging of α4β2* nicotinic acetylcholine receptors. Synapse. 2017 08; 71(8). Lao PJ, Betthauser TJ, Tudorascu DL, Barnhart TE, Hillmer AT, Stone CK, Mukherjee J, Christian BT. PMID: 28420041; PMCID: PMC5541262.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    28. Brain and Brown Adipose Tissue Metabolism in Transgenic Tg2576 Mice Models of Alzheimer Disease Assessed Using 18F-FDG PET Imaging. Mol Imaging. 2017 01 01; 16:1536012117704557. Coleman RA, Liang C, Patel R, Ali S, Mukherjee J. PMID: 28654383; PMCID: PMC5470140.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    29. PET radiotracer development for imaging high-affinity state of dopamine D2 and D3 receptors: Binding studies of fluorine-18 labeled aminotetralins in rodents. Synapse. 2017 03; 71(3). Mukherjee J, Majji D, Kaur J, Constantinescu CC, Narayanan TK, Shi B, Nour MT, Pan ML. PMID: 27864853; PMCID: PMC5363407.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    30. Synthesis and evaluation of (S)-[(18)F]fesetron in the rat brain as a potential PET imaging agent for serotonin 5-HT3 receptors. Bioorg Med Chem Lett. 2016 Apr 15; 26(8):1919-24. Pithia NK, Liang C, Pan XZ, Pan ML, Mukherjee J. PMID: 26979158; PMCID: PMC5360103.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    31. Evaluation of [11C]TAZA for amyloid β plaque imaging in postmortem human Alzheimer's disease brain region and whole body distribution in rodent PET/CT. Synapse. 2016 Apr; 70(4):163-76. Pan ML, Mukherjee MT, Patel HH, Patel B, Constantinescu CC, Mirbolooki MR, Liang C, Mukherjee J. PMID: 26806100; PMCID: PMC5358321.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    32. Classification of Therapeutic and Experimental Drugs for Brown Adipose Tissue Activation: Potential Treatment Strategies for Diabetes and Obesity. Curr Diabetes Rev. 2016; 12(4):414-428. Mukherjee J, Baranwal A, Schade KN. PMID: 27183844; PMCID: PMC5425649.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    33. Comparative assessment of (18) F-Mefway as a serotonin 5-HT1A receptor PET imaging agent across species: Rodents, nonhuman primates, and humans. J Comp Neurol. 2016 May 01; 524(7):1457-71. Mukherjee J, Bajwa AK, Wooten DW, Hillmer AT, Pan ML, Pandey SK, Saigal N, Christian BT. PMID: 26509362; PMCID: PMC4783179.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    34. Dopamine D3 receptor binding of (18)F-fallypride: Evaluation using in vitro and in vivo PET imaging studies. Synapse. 2015 Dec; 69(12):577-91. Mukherjee J, Constantinescu CC, Hoang AT, Jerjian T, Majji D, Pan ML. PMID: 26422464; PMCID: PMC4624469.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    35. (18)F-Fluorodeoxyglucamines: Reductive amination of hydrophilic (18)F-fluoro-2-deoxyglucose with lipophilic amines for the development of potential PET imaging agents. Bioorg Med Chem Lett. 2015 Aug 01; 25(15):2902-6. Baranwal A, Mukherjee J. PMID: 26048782; PMCID: PMC4469266.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    36. Preliminary evaluation of β3-adrenoceptor agonist-induced 18F-FDG metabolic activity of brown adipose tissue in obese Zucker rat. Nucl Med Biol. 2015 Aug; 42(8):691-4. Schade KN, Baranwal A, Liang C, Mirbolooki MR, Mukherjee J. PMID: 25934347; PMCID: PMC4481135.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    37. Synthesis and Evaluation of Mefway Analogs as Ligands for Serotonin 5HT1A Receptors. Med Chem Res. 2015 Apr; 24(4):1480-1486. Thio JP, Liang C, Bajwa AK, Wooten DW, Christian BT, Mukherjee J. PMID: 25750500; PMCID: PMC4349336.
      View in: PubMed   Mentions: 1  
    38. Initial Assessment of β3-Adrenoceptor-Activated Brown Adipose Tissue in Streptozotocin-Induced Type 1 Diabetes Rodent Model Using [18F]Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography. Mol Imaging. 2015; 14(12):22-33. Baranwal A, Mirbolooki MR, Mukherjee J. PMID: 26637263.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    39. First-in-human evaluation of 18F-mefway, a PET radioligand specific to serotonin-1A receptors. J Nucl Med. 2014 Dec; 55(12):1973-9. Hillmer AT, Wooten DW, Bajwa AK, Higgins AT, Lao PJ, Betthauser TJ, Barnhart TE, Rowley HA, Stone CK, Johnson SC, Mukherjee J, Christian BT. PMID: 25453045; PMCID: PMC4316674.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    40. Enhancement of 18F-fluorodeoxyglucose metabolism in rat brain frontal cortex using a β3 adrenoceptor agonist. Synapse. 2015 Feb; 69(2):96-8. Mirbolooki MR, Schade KN, Constantinescu CC, Pan ML, Mukherjee J. PMID: 25347981; PMCID: PMC4275345.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    41. Initial in vivo PET imaging of 5-HT1A receptors with 3-[(18)F]mefway. Am J Nucl Med Mol Imaging. 2014; 4(5):483-9. Wooten DW, Hillmer AT, Murali D, Barnhart TE, Thio JP, Bajwa AK, Bonab AA, Normandin MD, Schneider ML, Mukherjee J, Christian BT. PMID: 25143866; PMCID: PMC4138142.
      View in: PubMed   Mentions: 2  
    42. Spinal cord dopamine D2/D3 receptors: in vivo and ex vivo imaging in the rat using (18)F/(11)C-fallypride. Nucl Med Biol. 2014 Nov-Dec; 41(10):841-7. Kaur J, Khararjian A, Coleman RA, Constantinescu CC, Pan ML, Mukherjee J. PMID: 25199843; PMCID: PMC4192035.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    43. Synthesis and evaluation of 2-(18)F-fluoro-5-iodo-3-[2-(S)-3,4-dehydropyrrolinylmethoxy]pyridine ((18)F-Niofene) as a potential imaging agent for nicotinic α4β2 receptors. Am J Nucl Med Mol Imaging. 2014; 4(4):354-64. Kuruvilla SA, Hillmer AT, Wooten DW, Patel A, Christian BT, Mukherjee J. PMID: 24982821; PMCID: PMC4074501.
      View in: PubMed   Mentions: 4  
    44. Targeting histone deacetylase in lung cancer for early diagnosis: (18)F-FAHA PET/CT imaging of NNK-treated A/J mice model. Am J Nucl Med Mol Imaging. 2014; 4(4):324-32. Tang W, Kuruvilla SA, Galitovskiy V, Pan ML, Grando SA, Mukherjee J. PMID: 24982818; PMCID: PMC4074498.
      View in: PubMed   Mentions: 4  
    45. Imaging pancreas in healthy and diabetic rodent model using [18F]fallypride positron emission tomography/computed tomography. Diabetes Technol Ther. 2014 Oct; 16(10):640-3. Garcia A, Venugopal A, Pan ML, Mukherjee J. PMID: 24828096; PMCID: PMC4183907.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    46. ¹²⁴I-Epidepride: a PET radiotracer for extended imaging of dopamine D2/D3 receptors. Nucl Med Biol. 2014 May-Jun; 41(5):426-31. Pandey S, Venugopal A, Kant R, Coleman R, Mukherjee J. PMID: 24602412; PMCID: PMC4004701.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    47. 2-deoxy-2-[18F]fluoro-D-mannose positron emission tomography imaging in atherosclerosis. Nat Med. 2014 Feb; 20(2):215-9. Tahara N, Mukherjee J, de Haas HJ, Petrov AD, Tawakol A, Haider N, Tahara A, Constantinescu CC, Zhou J, Boersma HH, Imaizumi T, Nakano M, Finn A, Fayad Z, Virmani R, Fuster V, Bosca L, Narula J. PMID: 24412923.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    48. Multimodality imaging probe for positron emission tomography and fluorescence imaging studies. Mol Imaging. 2014; 13:1-7. Pandey SK, Kaur J, Easwaramoorthy B, Shah A, Coleman R, Mukherjee J. PMID: 24824856.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    49. 18F-Fluorodeoxyglycosylamines: Maillard reaction of 18F-fluorodeoxyglucose with biological amines. J Labelled Comp Radiopharm. 2014 Feb; 57(2):86-91. Baranwal A, Patel HH, Mukherjee J. PMID: 24327460; PMCID: PMC5569313.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    50. Adrenergic pathway activation enhances brown adipose tissue metabolism: a [¹⁸F]FDG PET/CT study in mice. Nucl Med Biol. 2014 Jan; 41(1):10-6. Mirbolooki MR, Upadhyay SK, Constantinescu CC, Pan ML, Mukherjee J. PMID: 24090673; PMCID: PMC3840120.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    51. D2 receptor occupancy following lurasidone treatment in patients with schizophrenia or schizoaffective disorder. CNS Spectr. 2014 Apr; 19(2):176-81. Potkin SG, Keator DB, Kesler-West ML, Nguyen DD, van Erp TG, Mukherjee J, Shah N, Preda A. PMID: 24073841.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    52. PET imaging of acetylcholinesterase inhibitor-induced effects on α4β2 nicotinic acetylcholine receptor binding. Synapse. 2013 Dec; 67(12):882-6. Hillmer AT, Wooten DW, Farhoud M, Higgins AT, Lao PJ, Barnhart TE, Mukherjee J, Christian BT. PMID: 23913347; PMCID: PMC3806056.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    53. Measuring α4β2* nicotinic acetylcholine receptor density in vivo with [(18)F]nifene PET in the nonhuman primate. J Cereb Blood Flow Metab. 2013 Nov; 33(11):1806-14. Hillmer AT, Wooten DW, Slesarev MS, Ahlers EO, Barnhart TE, Schneider ML, Mukherjee J, Christian BT. PMID: 23942367; PMCID: PMC3824181.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    54. Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):E2239-48. Upadhyay SK, Eckel-Mahan KL, Mirbolooki MR, Tjong I, Griffey SM, Schmunk G, Koehne A, Halbout B, Iadonato S, Pedersen B, Borrelli E, Wang PH, Mukherjee J, Sassone-Corsi P, Chandy KG. PMID: 23729813; PMCID: PMC3683782.
      View in: PubMed   Mentions: 44     Fields:    Translation:Animals
    55. Evaluation of serotonin 5-HT(1A) receptors in rodent models using [¹⁸F]mefway PET. Synapse. 2013 Sep; 67(9):596-608. Saigal N, Bajwa AK, Faheem SS, Coleman RA, Pandey SK, Constantinescu CC, Fong V, Mukherjee J. PMID: 23504990; PMCID: PMC3744326.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    56. Synthesis and biological evaluation of 18F-Norfallypride in the rodent brain using PET imaging. Nucl Med Biol. 2013 Jul; 40(5):697-704. Pithia N, Gulati N, Pandey S, Coleman R, Kant R, Mukherjee J. PMID: 23562464; PMCID: PMC3752033.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    57. Evaluation of [18F]Mefway biodistribution and dosimetry based on whole-body PET imaging of mice. Mol Imaging Biol. 2013 Apr; 15(2):222-9. Constantinescu CC, Sevrioukov E, Garcia A, Pan ML, Mukherjee J. PMID: 22833323; PMCID: PMC3808848.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    58. 5-HT1A sex based differences in Bmax, in vivo KD, and BPND in the nonhuman primate. Neuroimage. 2013 Aug 15; 77:125-32. Wooten DW, Hillmer AT, Moirano JM, Tudorascu DL, Ahlers EO, Slesarev MS, Barnhart TE, Mukherjee J, Schneider ML, Christian BT. PMID: 23537936; PMCID: PMC3654069.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    59. The effects of lobeline on α4β2* nicotinic acetylcholine receptor binding and uptake of [(18)F]nifene in rats. J Neurosci Methods. 2013 Apr 15; 214(2):163-9. Hillmer AT, Wooten DW, Farhoud M, Barnhart TE, Mukherjee J, Christian BT. PMID: 23370310; PMCID: PMC3644313.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    60. Evaluation of [18F]Nifene biodistribution and dosimetry based on whole-body PET imaging of mice. Nucl Med Biol. 2013 Feb; 40(2):289-94. Constantinescu CC, Garcia A, Mirbolooki MR, Pan ML, Mukherjee J. PMID: 23265670; PMCID: PMC3557576.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    61. A progressive translational mouse model of human valosin-containing protein disease: the VCP(R155H/+) mouse. Muscle Nerve. 2013 Feb; 47(2):260-70. Nalbandian A, Llewellyn KJ, Badadani M, Yin HZ, Nguyen C, Katheria V, Watts G, Mukherjee J, Vesa J, Caiozzo V, Mozaffar T, Weiss JH, Kimonis VE. PMID: 23169451; PMCID: PMC3556223.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    62. Targeting presynaptic norepinephrine transporter in brown adipose tissue: a novel imaging approach and potential treatment for diabetes and obesity. Synapse. 2013 Feb; 67(2):79-93. Mirbolooki MR, Constantinescu CC, Pan ML, Mukherjee J. PMID: 23080264; PMCID: PMC3808851.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    63. Nicotinic α4β2 receptor imaging agents. Part IV. Synthesis and biological evaluation of 3-(2-(S)-3,4-dehydropyrrolinyl methoxy)-5-(3'-¹⁸F-fluoropropyl)pyridine (¹⁸F-Nifrolene) using PET. Nucl Med Biol. 2013 Jan; 40(1):117-25. Pichika R, Kuruvilla SA, Patel N, Vu K, Sinha S, Easwaramoorthy B, Narayanan TK, Shi B, Christian B, Mukherjee J. PMID: 23141552; PMCID: PMC3514651.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    64. Synthesis and evaluation of 3-¹²³I-iodo-5-[2-(S)-3-pyrrolinylmethoxy]-pyridine (niodene) as a potential nicotinic α4β2 receptor imaging agent. Bioorg Med Chem Lett. 2012 Dec 15; 22(24):7610-4. Pandey SK, Pan S, Kant R, Kuruvilla SA, Pan ML, Mukherjee J. PMID: 23116890; PMCID: PMC3508149.
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    65. The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology. PLoS One. 2012; 7(9):e46308. Nalbandian A, Llewellyn KJ, Kitazawa M, Yin HZ, Badadani M, Khanlou N, Edwards R, Nguyen C, Mukherjee J, Mozaffar T, Watts G, Weiss J, Kimonis VE. PMID: 23029473; PMCID: PMC3460820.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    66. PET imaging of α4β2* nicotinic acetylcholine receptors: quantitative analysis of 18F-nifene kinetics in the nonhuman primate. J Nucl Med. 2012 Sep; 53(9):1471-80. Hillmer AT, Wooten DW, Slesarev MS, Ahlers EO, Barnhart TE, Murali D, Schneider ML, Mukherjee J, Christian BT. PMID: 22851633; PMCID: PMC3580212.
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    67. Measurement of 5-HT(1A) receptor density and in-vivo binding parameters of [(18)F]mefway in the nonhuman primate. J Cereb Blood Flow Metab. 2012 Aug; 32(8):1546-58. Wooten DW, Hillmer AT, Moirano JM, Ahlers EO, Slesarev M, Barnhart TE, Mukherjee J, Schneider ML, Christian BT. PMID: 22472611; PMCID: PMC3421091.
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    68. Nicotinic acetylcholine receptors in rat forebrain that bind ¹⁸F-nifene: relating PET imaging, autoradiography, and behavior. Synapse. 2012 May; 66(5):418-34. Bieszczad KM, Kant R, Constantinescu CC, Pandey SK, Kawai HD, Metherate R, Weinberger NM, Mukherjee J. PMID: 22213342; PMCID: PMC3292694.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    69. Ketoconazole-associated preferential increase in dopamine D2 receptor occupancy in striatum compared to pituitary in vivo: role for drug transporters? J Clin Psychopharmacol. 2012 Feb; 32(1):110-3. Reist C, Wu JC, Lilja Y, Mukherjee J, Gripeos D, Constantinescu C, Raggi MA, Mercolini L, Ozdemir V. PMID: 22198458.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    70. Quantitative assessment of brown adipose tissue metabolic activity and volume using 18F-FDG PET/CT and β3-adrenergic receptor activation. EJNMMI Res. 2011 Dec 01; 1(1):30. Mirbolooki MR, Constantinescu CC, Pan ML, Mukherjee J. PMID: 22214183; PMCID: PMC3250993.
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    71. The multiple faces of valosin-containing protein-associated diseases: inclusion body myopathy with Paget's disease of bone, frontotemporal dementia, and amyotrophic lateral sclerosis. J Mol Neurosci. 2011 Nov; 45(3):522-31. Nalbandian A, Donkervoort S, Dec E, Badadani M, Katheria V, Rana P, Nguyen C, Mukherjee J, Caiozzo V, Martin B, Watts GD, Vesa J, Smith C, Kimonis VE. PMID: 21892620.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimals
    72. Nicotinic α4β2 receptor imaging agents. Part III. Synthesis and biological evaluation of 3-(2-(S)-azetidinylmethoxy)-5-(3'-18F-fluoropropyl)pyridine (18F-nifzetidine). Nucl Med Biol. 2011 Nov; 38(8):1183-92. Pichika R, Easwaramoorthy B, Christian BT, Shi B, Narayanan TK, Collins D, Mukherjee J. PMID: 21831652; PMCID: PMC3217100.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    73. An in vivo comparison of cis- and trans-[18F]mefway in the nonhuman primate. Nucl Med Biol. 2011 Oct; 38(7):925-32. Wooten D, Hillmer A, Murali D, Barnhart T, Schneider ML, Mukherjee J, Christian BT. PMID: 21741252; PMCID: PMC3190069.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    74. 18F-Fallypride PET of pancreatic islets: in vitro and in vivo rodent studies. J Nucl Med. 2011 Jul; 52(7):1125-32. Garcia A, Mirbolooki MR, Constantinescu C, Pan ML, Sevrioukov E, Milne N, Wang PH, Lakey J, Chandy KG, Mukherjee J. PMID: 21680697.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    75. Evaluation of F-nifene binding to α4β2 nicotinic receptors in the rat brain using microPET imaging. EJNMMI Res. 2011 Jun 01; 1. Kant R, Constantinescu CC, Parekh P, Pandey SK, Pan ML, Easwaramoorthy B, Mukherjee J. PMID: 22039577; PMCID: PMC3203019.
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    76. Striatal and extrastriatal microPET imaging of D2/D3 dopamine receptors in rat brain with [¹⁸F]fallypride and [¹⁸F]desmethoxyfallypride. Synapse. 2011 Aug; 65(8):778-87. Constantinescu CC, Coleman RA, Pan ML, Mukherjee J. PMID: 21218455; PMCID: PMC3107916.
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    77. VCP associated inclusion body myopathy and paget disease of bone knock-in mouse model exhibits tissue pathology typical of human disease. PLoS One. 2010 Oct 05; 5(10). Badadani M, Nalbandian A, Watts GD, Vesa J, Kitazawa M, Su H, Tanaja J, Dec E, Wallace DC, Mukherjee J, Caiozzo V, Warman M, Kimonis VE. PMID: 20957154; PMCID: PMC2950155.
      View in: PubMed   Mentions: 66     Fields:    Translation:Animals
    78. (R)-N-Methyl-3-(3'-[F]fluoropropyl)phenoxy)-3-phenylpropanamine (F-MFP3) as a potential PET imaging agent for norepinephrine transporter. J Labelled Comp Radiopharm. 2010 Feb 09; 53(4):172-177. Nguyen VL, Pichika R, Bhakta PH, Kant R, Mukherjee J. PMID: 20495670; PMCID: PMC2873203.
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    79. Striatal dopamine d2/d3 receptor availability is reduced in methamphetamine dependence and is linked to impulsivity. J Neurosci. 2009 Nov 25; 29(47):14734-40. Lee B, London ED, Poldrack RA, Farahi J, Nacca A, Monterosso JR, Mumford JA, Bokarius AV, Dahlbom M, Mukherjee J, Bilder RM, Brody AL, Mandelkern MA. PMID: 19940168; PMCID: PMC2822639.
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    80. Performance evaluation of an Inveon PET preclinical scanner. Phys Med Biol. 2009 May 07; 54(9):2885-99. Constantinescu CC, Mukherjee J. PMID: 19384008; PMCID: PMC2838767.
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    81. [11C]cyclopropyl-FLB 457: a PET radioligand for low densities of dopamine D2 receptors. Bioorg Med Chem. 2008 Jul 01; 16(13):6467-73. Airaksinen AJ, Nag S, Finnema SJ, Mukherjee J, Chattopadhyay S, Gulyás B, Farde L, Halldin C. PMID: 18534857; PMCID: PMC2531229.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    82. 11C-L-methionine positron emission tomography in the clinical management of cerebral gliomas. Mol Imaging Biol. 2008 Jan-Feb; 10(1):1-18. Singhal T, Narayanan TK, Jain V, Mukherjee J, Mantil J. PMID: 17957408.
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    83. Effect of acetylcholinesterase inhibitors on the binding of nicotinic alpha4beta2 receptor PET radiotracer, (18)F-nifene: A measure of acetylcholine competition. Synapse. 2007 Jan; 61(1):29-36. Easwaramoorthy B, Pichika R, Collins D, Potkin SG, Leslie FM, Mukherjee J. PMID: 17068780.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    84. Synthesis and biologic evaluation of a novel serotonin 5-HT1A receptor radioligand, 18F-labeled mefway, in rodents and imaging by PET in a nonhuman primate. J Nucl Med. 2006 Oct; 47(10):1697-706. Saigal N, Pichika R, Easwaramoorthy B, Collins D, Christian BT, Shi B, Narayanan TK, Potkin SG, Mukherjee J. PMID: 17015907.
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    85. D2/D3 dopamine receptor binding with [F-18]fallypride in thalamus and cortex of patients with schizophrenia. Schizophr Res. 2006 Jul; 85(1-3):232-44. Buchsbaum MS, Christian BT, Lehrer DS, Narayanan TK, Shi B, Mantil J, Kemether E, Oakes TR, Mukherjee J. PMID: 16713185.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    86. Nicotinic alpha4beta2 receptor imaging agents: part II. Synthesis and biological evaluation of 2-[18F]fluoro-3-[2-((S)-3-pyrrolinyl)methoxy]pyridine (18F-nifene) in rodents and imaging by PET in nonhuman primate. Nucl Med Biol. 2006 Apr; 33(3):295-304. Pichika R, Easwaramoorthy B, Collins D, Christian BT, Shi B, Narayanan TK, Potkin SG, Mukherjee J. PMID: 16631077.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    87. Positron autoradiography for intravascular imaging: feasibility evaluation. Phys Med Biol. 2006 Feb 21; 51(4):963-79. Shikhaliev PM, Xu T, Ducote JL, Easwaramoorthy B, Mukherjee J, Molloi S. PMID: 16467590.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    88. Moderate-level prenatal alcohol exposure alters striatal dopamine system function in rhesus monkeys. Alcohol Clin Exp Res. 2005 Sep; 29(9):1685-97. Schneider ML, Moore CF, Barnhart TE, Larson JA, DeJesus OT, Mukherjee J, Nickles RJ, Converse AK, Roberts AD, Kraemer GW. PMID: 16205369.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    89. Measurement of d-amphetamine-induced effects on the binding of dopamine D-2/D-3 receptor radioligand, 18F-fallypride in extrastriatal brain regions in non-human primates using PET. Brain Res. 2005 Jan 25; 1032(1-2):77-84. Mukherjee J, Christian BT, Narayanan TK, Shi B, Collins D. PMID: 15680944.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    90. Synthesis and evaluation of nicotine alpha4beta2 receptor radioligand, 5-(3'-18F-fluoropropyl)-3-(2-(S)-pyrrolidinylmethoxy)pyridine, in rodents and PET in nonhuman primate. J Nucl Med. 2005 Jan; 46(1):130-40. Chattopadhyay S, Xue B, Collins D, Pichika R, Bagnera R, Leslie FM, Christian BT, Shi B, Narayanan TK, Potkin SG, Mukherjee J. PMID: 15632043.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    91. Binding characteristics of high-affinity dopamine D2/D3 receptor agonists, 11C-PPHT and 11C-ZYY-339 in rodents and imaging in non-human primates by PET. Synapse. 2004 Nov; 54(2):83-91. Mukherjee J, Narayanan TK, Christian BT, Shi B, Yang ZY. PMID: 15352133.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    92. Synthesis and biological evaluation of the binding of dopamine D2/D3 receptor agonist, (R,S)-5-hydroxy-2-(N-propyl-N-(5'-(18)F-fluoropentyl)aminotetralin ((18)F-5-OH-FPPAT) in rodents and nonhuman primates. Nucl Med Biol. 2004 Apr; 31(3):303-11. Shi B, Narayanan TK, Christian BT, Chattopadhyay S, Mukherjee J. PMID: 15028242.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    93. Measuring the in vivo binding parameters of [18F]-fallypride in monkeys using a PET multiple-injection protocol. J Cereb Blood Flow Metab. 2004 Mar; 24(3):309-22. Christian BT, Narayanan T, Shi B, Morris ED, Mantil J, Mukherjee J. PMID: 15091112.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    94. 11C-Fallypride: radiosynthesis and preliminary evaluation of a novel dopamine D2/D3 receptor PET radiotracer in non-human primate brain. Bioorg Med Chem. 2004 Jan 02; 12(1):95-102. Mukherjee J, Shi B, Christian BT, Chattopadhyay S, Narayanan TK. PMID: 14697774.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    95. A comparative study on the uptake and incorporation of radiolabeled methionine, choline and fluorodeoxyglucose in human astrocytoma. Mol Imaging Biol. 2002 Mar; 4(2):147-56. Narayanan TK, Said S, Mukherjee J, Christian B, Satter M, Dunigan K, Shi B, Jacobs M, Bernstein T, Padma M, Mantil J. PMID: 14537137.
      View in: PubMed   Mentions: 12     Fields:    
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